Incidental Mutation 'R4770:Nr3c2'
ID |
367414 |
Institutional Source |
Beutler Lab
|
Gene Symbol |
Nr3c2
|
Ensembl Gene |
ENSMUSG00000031618 |
Gene Name |
nuclear receptor subfamily 3, group C, member 2 |
Synonyms |
mineralocorticoid receptor, MR, aldosterone receptor, Mlr |
MMRRC Submission |
042410-MU
|
Accession Numbers |
|
Essential gene? |
Essential
(E-score: 1.000)
|
Stock # |
R4770 (G1)
|
Quality Score |
225 |
Status
|
Validated
|
Chromosome |
8 |
Chromosomal Location |
77626070-77971641 bp(+) (GRCm39) |
Type of Mutation |
splice site |
DNA Base Change (assembly) |
A to G
at 77634872 bp (GRCm39)
|
Zygosity |
Heterozygous |
Amino Acid Change |
|
Ref Sequence |
ENSEMBL: ENSMUSP00000122959
(fasta)
|
Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000034031]
[ENSMUST00000109911]
[ENSMUST00000109911]
[ENSMUST00000109912]
[ENSMUST00000109912]
[ENSMUST00000109913]
[ENSMUST00000109913]
[ENSMUST00000128862]
[ENSMUST00000128862]
[ENSMUST00000143284]
[ENSMUST00000143284]
[ENSMUST00000148106]
|
AlphaFold |
no structure available at present |
Predicted Effect |
probably null
Transcript: ENSMUST00000034031
|
SMART Domains |
Protein: ENSMUSP00000034031 Gene: ENSMUSG00000031618
Domain | Start | End | E-Value | Type |
low complexity region
|
212 |
222 |
N/A |
INTRINSIC |
low complexity region
|
259 |
277 |
N/A |
INTRINSIC |
low complexity region
|
280 |
300 |
N/A |
INTRINSIC |
low complexity region
|
346 |
354 |
N/A |
INTRINSIC |
low complexity region
|
584 |
598 |
N/A |
INTRINSIC |
ZnF_C4
|
600 |
675 |
1.89e-31 |
SMART |
low complexity region
|
690 |
706 |
N/A |
INTRINSIC |
HOLI
|
771 |
935 |
7.78e-33 |
SMART |
|
Predicted Effect |
probably null
Transcript: ENSMUST00000109911
|
SMART Domains |
Protein: ENSMUSP00000105537 Gene: ENSMUSG00000031618
Domain | Start | End | E-Value | Type |
low complexity region
|
212 |
222 |
N/A |
INTRINSIC |
low complexity region
|
259 |
277 |
N/A |
INTRINSIC |
low complexity region
|
280 |
300 |
N/A |
INTRINSIC |
low complexity region
|
346 |
354 |
N/A |
INTRINSIC |
low complexity region
|
584 |
598 |
N/A |
INTRINSIC |
ZnF_C4
|
600 |
671 |
5.29e-35 |
SMART |
HOLI
|
658 |
818 |
1.1e-23 |
SMART |
|
Predicted Effect |
probably null
Transcript: ENSMUST00000109911
|
SMART Domains |
Protein: ENSMUSP00000105537 Gene: ENSMUSG00000031618
Domain | Start | End | E-Value | Type |
low complexity region
|
212 |
222 |
N/A |
INTRINSIC |
low complexity region
|
259 |
277 |
N/A |
INTRINSIC |
low complexity region
|
280 |
300 |
N/A |
INTRINSIC |
low complexity region
|
346 |
354 |
N/A |
INTRINSIC |
low complexity region
|
584 |
598 |
N/A |
INTRINSIC |
ZnF_C4
|
600 |
671 |
5.29e-35 |
SMART |
HOLI
|
658 |
818 |
1.1e-23 |
SMART |
|
Predicted Effect |
probably null
Transcript: ENSMUST00000109912
|
SMART Domains |
Protein: ENSMUSP00000105538 Gene: ENSMUSG00000031618
Domain | Start | End | E-Value | Type |
low complexity region
|
212 |
222 |
N/A |
INTRINSIC |
low complexity region
|
259 |
277 |
N/A |
INTRINSIC |
low complexity region
|
280 |
300 |
N/A |
INTRINSIC |
low complexity region
|
346 |
354 |
N/A |
INTRINSIC |
low complexity region
|
584 |
598 |
N/A |
INTRINSIC |
ZnF_C4
|
600 |
671 |
5.29e-35 |
SMART |
low complexity region
|
686 |
702 |
N/A |
INTRINSIC |
HOLI
|
767 |
931 |
7.78e-33 |
SMART |
|
Predicted Effect |
probably null
Transcript: ENSMUST00000109912
|
SMART Domains |
Protein: ENSMUSP00000105538 Gene: ENSMUSG00000031618
Domain | Start | End | E-Value | Type |
low complexity region
|
212 |
222 |
N/A |
INTRINSIC |
low complexity region
|
259 |
277 |
N/A |
INTRINSIC |
low complexity region
|
280 |
300 |
N/A |
INTRINSIC |
low complexity region
|
346 |
354 |
N/A |
INTRINSIC |
low complexity region
|
584 |
598 |
N/A |
INTRINSIC |
ZnF_C4
|
600 |
671 |
5.29e-35 |
SMART |
low complexity region
|
686 |
702 |
N/A |
INTRINSIC |
HOLI
|
767 |
931 |
7.78e-33 |
SMART |
|
Predicted Effect |
probably null
Transcript: ENSMUST00000109913
|
SMART Domains |
Protein: ENSMUSP00000105539 Gene: ENSMUSG00000031618
Domain | Start | End | E-Value | Type |
low complexity region
|
212 |
222 |
N/A |
INTRINSIC |
low complexity region
|
259 |
277 |
N/A |
INTRINSIC |
low complexity region
|
280 |
300 |
N/A |
INTRINSIC |
low complexity region
|
346 |
354 |
N/A |
INTRINSIC |
low complexity region
|
584 |
598 |
N/A |
INTRINSIC |
ZnF_C4
|
600 |
671 |
5.29e-35 |
SMART |
low complexity region
|
686 |
702 |
N/A |
INTRINSIC |
HOLI
|
767 |
931 |
7.78e-33 |
SMART |
|
Predicted Effect |
probably null
Transcript: ENSMUST00000109913
|
SMART Domains |
Protein: ENSMUSP00000105539 Gene: ENSMUSG00000031618
Domain | Start | End | E-Value | Type |
low complexity region
|
212 |
222 |
N/A |
INTRINSIC |
low complexity region
|
259 |
277 |
N/A |
INTRINSIC |
low complexity region
|
280 |
300 |
N/A |
INTRINSIC |
low complexity region
|
346 |
354 |
N/A |
INTRINSIC |
low complexity region
|
584 |
598 |
N/A |
INTRINSIC |
ZnF_C4
|
600 |
671 |
5.29e-35 |
SMART |
low complexity region
|
686 |
702 |
N/A |
INTRINSIC |
HOLI
|
767 |
931 |
7.78e-33 |
SMART |
|
Predicted Effect |
probably null
Transcript: ENSMUST00000128862
|
Predicted Effect |
probably null
Transcript: ENSMUST00000128862
|
Predicted Effect |
probably null
Transcript: ENSMUST00000143284
|
Predicted Effect |
probably null
Transcript: ENSMUST00000143284
|
Predicted Effect |
probably benign
Transcript: ENSMUST00000148106
|
SMART Domains |
Protein: ENSMUSP00000118222 Gene: ENSMUSG00000031618
Domain | Start | End | E-Value | Type |
low complexity region
|
212 |
222 |
N/A |
INTRINSIC |
low complexity region
|
259 |
277 |
N/A |
INTRINSIC |
low complexity region
|
280 |
300 |
N/A |
INTRINSIC |
low complexity region
|
346 |
354 |
N/A |
INTRINSIC |
low complexity region
|
584 |
598 |
N/A |
INTRINSIC |
ZnF_C4
|
600 |
671 |
5.29e-35 |
SMART |
|
Meta Mutation Damage Score |
0.9755 |
Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.7%
|
Validation Efficiency |
93% (89/96) |
MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] PHENOTYPE: Mice homozygous for a targeted null mutation exhibit weight loss and symptoms of pseudohypoaldosteronism, and eventually die at around day 10 after birth from renal salt wasting and dehydration. [provided by MGI curators]
|
Allele List at MGI |
|
Other mutations in this stock |
Total: 83 list
Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
Abca8a |
A |
G |
11: 109,962,341 (GRCm39) |
V503A |
possibly damaging |
Het |
Agps |
T |
A |
2: 75,722,199 (GRCm39) |
F463Y |
possibly damaging |
Het |
Ajm1 |
G |
A |
2: 25,469,759 (GRCm39) |
R51C |
possibly damaging |
Het |
Amigo3 |
A |
T |
9: 107,930,734 (GRCm39) |
L52F |
probably damaging |
Het |
Anapc1 |
T |
C |
2: 128,527,980 (GRCm39) |
|
probably benign |
Het |
Ankrd36 |
G |
T |
11: 5,540,870 (GRCm39) |
C312F |
possibly damaging |
Het |
Asic2 |
A |
C |
11: 80,862,318 (GRCm39) |
D226E |
probably benign |
Het |
Atp8b2 |
T |
A |
3: 89,864,374 (GRCm39) |
Q197L |
probably damaging |
Het |
C2cd3 |
A |
G |
7: 100,092,642 (GRCm39) |
Y495C |
probably damaging |
Het |
Ccdc51 |
A |
G |
9: 108,919,978 (GRCm39) |
T125A |
probably benign |
Het |
Ccser1 |
A |
G |
6: 61,288,485 (GRCm39) |
Y216C |
possibly damaging |
Het |
Cimap1b |
A |
G |
15: 89,263,326 (GRCm39) |
I19T |
probably damaging |
Het |
Cntfr |
A |
T |
4: 41,663,282 (GRCm39) |
I175N |
possibly damaging |
Het |
Cox10 |
G |
A |
11: 63,854,989 (GRCm39) |
R431W |
probably benign |
Het |
Cubn |
T |
C |
2: 13,319,578 (GRCm39) |
T2881A |
possibly damaging |
Het |
Cyp2d9 |
T |
A |
15: 82,336,774 (GRCm39) |
V41E |
probably damaging |
Het |
Dmrtb1 |
C |
T |
4: 107,540,986 (GRCm39) |
G125D |
probably benign |
Het |
Dscaml1 |
C |
T |
9: 45,581,404 (GRCm39) |
R408C |
probably damaging |
Het |
Duox2 |
A |
T |
2: 122,115,397 (GRCm39) |
S1052T |
probably benign |
Het |
Ecm1 |
A |
G |
3: 95,645,273 (GRCm39) |
|
probably benign |
Het |
Edrf1 |
G |
T |
7: 133,260,339 (GRCm39) |
M83I |
probably damaging |
Het |
Epb41l1 |
T |
A |
2: 156,371,344 (GRCm39) |
M727K |
probably benign |
Het |
Exosc9 |
T |
C |
3: 36,607,984 (GRCm39) |
V64A |
probably damaging |
Het |
Ezh2 |
A |
T |
6: 47,517,630 (GRCm39) |
I564N |
probably damaging |
Het |
Fam89b |
C |
A |
19: 5,779,482 (GRCm39) |
R25L |
probably damaging |
Het |
Fgr |
C |
T |
4: 132,714,602 (GRCm39) |
T98M |
probably damaging |
Het |
Fhip2b |
T |
A |
14: 70,825,727 (GRCm39) |
D351V |
probably damaging |
Het |
Gapvd1 |
A |
G |
2: 34,581,193 (GRCm39) |
S1089P |
probably damaging |
Het |
Gbp5 |
A |
T |
3: 142,213,837 (GRCm39) |
I544F |
possibly damaging |
Het |
Gli2 |
C |
A |
1: 118,910,318 (GRCm39) |
|
probably benign |
Het |
Gm9934 |
A |
G |
7: 92,702,192 (GRCm39) |
|
noncoding transcript |
Het |
Greb1 |
A |
T |
12: 16,731,357 (GRCm39) |
D1660E |
probably benign |
Het |
Gtf2i |
T |
A |
5: 134,272,414 (GRCm39) |
N750I |
possibly damaging |
Het |
H2-DMb2 |
G |
C |
17: 34,367,698 (GRCm39) |
D171H |
probably damaging |
Het |
Il11ra1 |
A |
G |
4: 41,768,187 (GRCm39) |
E366G |
probably damaging |
Het |
Itga2b |
A |
G |
11: 102,351,582 (GRCm39) |
F581S |
probably damaging |
Het |
Itsn2 |
T |
A |
12: 4,677,892 (GRCm39) |
M83K |
probably damaging |
Het |
Kif27 |
G |
A |
13: 58,492,191 (GRCm39) |
T316M |
probably damaging |
Het |
Lad1 |
A |
T |
1: 135,753,531 (GRCm39) |
Q26L |
probably damaging |
Het |
Lrrn3 |
T |
A |
12: 41,502,442 (GRCm39) |
H625L |
probably benign |
Het |
Mast1 |
A |
G |
8: 85,655,875 (GRCm39) |
V155A |
probably benign |
Het |
Mast3 |
G |
A |
8: 71,238,864 (GRCm39) |
T480M |
probably damaging |
Het |
Mpc1 |
C |
T |
17: 8,512,377 (GRCm39) |
|
probably benign |
Het |
Mycbp2 |
T |
A |
14: 103,457,380 (GRCm39) |
M1606L |
probably benign |
Het |
Myo1c |
T |
A |
11: 75,551,139 (GRCm39) |
L238* |
probably null |
Het |
Nanog |
T |
G |
6: 122,688,550 (GRCm39) |
S44A |
possibly damaging |
Het |
Neb |
T |
C |
2: 52,039,165 (GRCm39) |
Q6958R |
probably benign |
Het |
Ngef |
C |
T |
1: 87,405,283 (GRCm39) |
R709H |
probably damaging |
Het |
Nr1d1 |
A |
G |
11: 98,661,471 (GRCm39) |
V265A |
probably benign |
Het |
Olfm5 |
A |
G |
7: 103,809,685 (GRCm39) |
S164P |
probably benign |
Het |
Parvb |
T |
C |
15: 84,188,106 (GRCm39) |
|
probably null |
Het |
Pde4dip |
G |
T |
3: 97,674,400 (GRCm39) |
A172D |
probably damaging |
Het |
Phf2 |
A |
G |
13: 48,957,079 (GRCm39) |
L1096P |
probably damaging |
Het |
Pik3r6 |
T |
A |
11: 68,420,720 (GRCm39) |
V155E |
probably damaging |
Het |
Pinx1 |
T |
G |
14: 64,109,820 (GRCm39) |
V124G |
probably damaging |
Het |
Poglut1 |
A |
G |
16: 38,355,119 (GRCm39) |
Y236H |
probably damaging |
Het |
Pou4f2 |
T |
A |
8: 79,163,030 (GRCm39) |
M2L |
unknown |
Het |
Ppfia2 |
G |
C |
10: 106,597,978 (GRCm39) |
L180F |
probably damaging |
Het |
Pramel26 |
C |
T |
4: 143,538,519 (GRCm39) |
E151K |
probably damaging |
Het |
Prkaca |
A |
G |
8: 84,717,499 (GRCm39) |
N209S |
probably benign |
Het |
Ring1 |
G |
A |
17: 34,242,361 (GRCm39) |
P49S |
probably damaging |
Het |
Rnf20 |
T |
A |
4: 49,633,412 (GRCm39) |
|
probably null |
Het |
Rnf25 |
G |
A |
1: 74,633,099 (GRCm39) |
R418C |
probably damaging |
Het |
Ryr1 |
G |
T |
7: 28,808,707 (GRCm39) |
P462Q |
probably damaging |
Het |
Serpinb3d |
A |
G |
1: 107,006,008 (GRCm39) |
F360S |
probably damaging |
Het |
Setd7 |
T |
C |
3: 51,428,843 (GRCm39) |
E329G |
probably damaging |
Het |
Slco2b1 |
C |
T |
7: 99,320,156 (GRCm39) |
|
probably null |
Het |
Snap91 |
G |
A |
9: 86,655,654 (GRCm39) |
T844I |
possibly damaging |
Het |
Snhg5 |
C |
T |
9: 88,404,424 (GRCm39) |
|
noncoding transcript |
Het |
Son |
T |
A |
16: 91,455,756 (GRCm39) |
V1501E |
probably damaging |
Het |
Syncrip |
T |
A |
9: 88,361,905 (GRCm39) |
E70V |
probably damaging |
Het |
Tas2r125 |
A |
G |
6: 132,886,750 (GRCm39) |
D46G |
probably damaging |
Het |
Tmem115 |
G |
A |
9: 107,412,156 (GRCm39) |
R160Q |
probably benign |
Het |
Trerf1 |
G |
A |
17: 47,630,581 (GRCm39) |
|
noncoding transcript |
Het |
Tut7 |
A |
G |
13: 59,920,698 (GRCm39) |
|
probably benign |
Het |
Uggt2 |
A |
T |
14: 119,266,466 (GRCm39) |
|
probably null |
Het |
Ush2a |
G |
T |
1: 188,282,076 (GRCm39) |
V1864F |
probably benign |
Het |
Xkr4 |
A |
T |
1: 3,286,714 (GRCm39) |
V492D |
probably damaging |
Het |
Zfp646 |
T |
A |
7: 127,482,649 (GRCm39) |
S1609T |
possibly damaging |
Het |
Zfp65 |
A |
T |
13: 67,856,477 (GRCm39) |
H277Q |
probably damaging |
Het |
Zfp69 |
A |
G |
4: 120,791,614 (GRCm39) |
S176P |
probably damaging |
Het |
Zfp747 |
C |
T |
7: 126,974,971 (GRCm39) |
A10T |
probably damaging |
Het |
Zfp850 |
T |
C |
7: 27,684,411 (GRCm39) |
|
probably null |
Het |
|
Other mutations in Nr3c2 |
Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
IGL00691:Nr3c2
|
APN |
8 |
77,636,219 (GRCm39) |
missense |
possibly damaging |
0.82 |
IGL01019:Nr3c2
|
APN |
8 |
77,635,843 (GRCm39) |
missense |
probably damaging |
0.99 |
IGL01085:Nr3c2
|
APN |
8 |
77,634,983 (GRCm39) |
missense |
probably benign |
0.02 |
IGL01395:Nr3c2
|
APN |
8 |
77,635,477 (GRCm39) |
missense |
possibly damaging |
0.73 |
IGL01505:Nr3c2
|
APN |
8 |
77,635,816 (GRCm39) |
missense |
probably damaging |
1.00 |
IGL01656:Nr3c2
|
APN |
8 |
77,914,166 (GRCm39) |
missense |
probably damaging |
1.00 |
IGL01802:Nr3c2
|
APN |
8 |
77,635,224 (GRCm39) |
nonsense |
probably null |
|
IGL02147:Nr3c2
|
APN |
8 |
77,635,696 (GRCm39) |
missense |
probably damaging |
0.98 |
IGL02502:Nr3c2
|
APN |
8 |
77,969,143 (GRCm39) |
missense |
probably damaging |
1.00 |
IGL02706:Nr3c2
|
APN |
8 |
77,635,045 (GRCm39) |
splice site |
probably null |
|
IGL02945:Nr3c2
|
APN |
8 |
77,636,288 (GRCm39) |
missense |
probably damaging |
1.00 |
IGL03034:Nr3c2
|
APN |
8 |
77,914,267 (GRCm39) |
nonsense |
probably null |
|
IGL03162:Nr3c2
|
APN |
8 |
77,944,213 (GRCm39) |
missense |
probably damaging |
0.99 |
devalued
|
UTSW |
8 |
77,969,092 (GRCm39) |
missense |
probably damaging |
1.00 |
naughty
|
UTSW |
8 |
77,635,297 (GRCm39) |
splice site |
probably null |
|
R0141:Nr3c2
|
UTSW |
8 |
77,635,037 (GRCm39) |
missense |
probably damaging |
0.99 |
R0422:Nr3c2
|
UTSW |
8 |
77,912,596 (GRCm39) |
missense |
probably benign |
|
R0458:Nr3c2
|
UTSW |
8 |
77,636,167 (GRCm39) |
missense |
probably damaging |
1.00 |
R0595:Nr3c2
|
UTSW |
8 |
77,636,233 (GRCm39) |
missense |
possibly damaging |
0.93 |
R0615:Nr3c2
|
UTSW |
8 |
77,912,518 (GRCm39) |
missense |
probably benign |
0.05 |
R0964:Nr3c2
|
UTSW |
8 |
77,635,297 (GRCm39) |
splice site |
probably null |
|
R0989:Nr3c2
|
UTSW |
8 |
77,914,193 (GRCm39) |
missense |
probably damaging |
0.97 |
R1532:Nr3c2
|
UTSW |
8 |
77,635,733 (GRCm39) |
missense |
probably damaging |
0.99 |
R1624:Nr3c2
|
UTSW |
8 |
77,636,573 (GRCm39) |
missense |
probably damaging |
1.00 |
R1737:Nr3c2
|
UTSW |
8 |
77,634,958 (GRCm39) |
missense |
probably benign |
0.16 |
R1965:Nr3c2
|
UTSW |
8 |
77,636,092 (GRCm39) |
missense |
probably damaging |
0.99 |
R2011:Nr3c2
|
UTSW |
8 |
77,636,422 (GRCm39) |
missense |
possibly damaging |
0.53 |
R2110:Nr3c2
|
UTSW |
8 |
77,635,156 (GRCm39) |
missense |
possibly damaging |
0.75 |
R2281:Nr3c2
|
UTSW |
8 |
77,636,536 (GRCm39) |
missense |
probably damaging |
0.99 |
R3782:Nr3c2
|
UTSW |
8 |
77,812,313 (GRCm39) |
splice site |
probably null |
|
R3808:Nr3c2
|
UTSW |
8 |
77,635,343 (GRCm39) |
missense |
probably damaging |
1.00 |
R4133:Nr3c2
|
UTSW |
8 |
77,636,378 (GRCm39) |
missense |
probably damaging |
1.00 |
R4433:Nr3c2
|
UTSW |
8 |
77,944,096 (GRCm39) |
missense |
probably damaging |
1.00 |
R4738:Nr3c2
|
UTSW |
8 |
77,635,936 (GRCm39) |
missense |
possibly damaging |
0.94 |
R4884:Nr3c2
|
UTSW |
8 |
77,635,438 (GRCm39) |
missense |
possibly damaging |
0.53 |
R5169:Nr3c2
|
UTSW |
8 |
77,635,666 (GRCm39) |
missense |
probably damaging |
1.00 |
R5347:Nr3c2
|
UTSW |
8 |
77,937,377 (GRCm39) |
missense |
possibly damaging |
0.92 |
R5857:Nr3c2
|
UTSW |
8 |
77,635,496 (GRCm39) |
missense |
possibly damaging |
0.53 |
R5878:Nr3c2
|
UTSW |
8 |
77,634,897 (GRCm39) |
critical splice acceptor site |
probably null |
|
R6262:Nr3c2
|
UTSW |
8 |
77,635,262 (GRCm39) |
missense |
possibly damaging |
0.65 |
R6547:Nr3c2
|
UTSW |
8 |
77,635,438 (GRCm39) |
missense |
possibly damaging |
0.53 |
R6820:Nr3c2
|
UTSW |
8 |
77,969,086 (GRCm39) |
missense |
probably damaging |
0.98 |
R7180:Nr3c2
|
UTSW |
8 |
77,635,592 (GRCm39) |
missense |
probably damaging |
0.99 |
R7672:Nr3c2
|
UTSW |
8 |
77,635,838 (GRCm39) |
missense |
probably damaging |
1.00 |
R7741:Nr3c2
|
UTSW |
8 |
77,937,275 (GRCm39) |
missense |
probably damaging |
0.97 |
R7776:Nr3c2
|
UTSW |
8 |
77,636,174 (GRCm39) |
missense |
possibly damaging |
0.77 |
R7800:Nr3c2
|
UTSW |
8 |
77,636,621 (GRCm39) |
missense |
probably damaging |
1.00 |
R8742:Nr3c2
|
UTSW |
8 |
77,635,210 (GRCm39) |
missense |
probably damaging |
0.98 |
R8743:Nr3c2
|
UTSW |
8 |
77,636,387 (GRCm39) |
missense |
probably damaging |
1.00 |
R8806:Nr3c2
|
UTSW |
8 |
77,969,092 (GRCm39) |
missense |
probably damaging |
1.00 |
R8964:Nr3c2
|
UTSW |
8 |
77,881,941 (GRCm39) |
missense |
probably damaging |
1.00 |
R9265:Nr3c2
|
UTSW |
8 |
77,636,236 (GRCm39) |
missense |
probably benign |
|
R9280:Nr3c2
|
UTSW |
8 |
77,635,973 (GRCm39) |
missense |
probably benign |
0.00 |
Z1088:Nr3c2
|
UTSW |
8 |
77,635,261 (GRCm39) |
missense |
possibly damaging |
0.48 |
Z1176:Nr3c2
|
UTSW |
8 |
77,636,329 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Predicted Primers |
PCR Primer
(F):5'- TGCCAAGGCCCTATTATAGTGAG -3'
(R):5'- GACGTTGACAATCTCCATGTAGC -3'
Sequencing Primer
(F):5'- CACAAAATTGCAATTGGTTCTTCTGG -3'
(R):5'- GTTGACAATCTCCATGTAGCTGTTC -3'
|
Posted On |
2015-12-29 |