Incidental Mutation 'R4770:Myo1c'
| ID |
367428 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo1c
|
| Ensembl Gene |
ENSMUSG00000017774 |
| Gene Name |
myosin IC |
| Synonyms |
myr2, mm1beta, C80397, myosin-Ibeta |
| MMRRC Submission |
042410-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.697)
|
| Stock # |
R4770 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
75541330-75564736 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 75551139 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Stop codon
at position 238
(L238*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104069
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000069057]
[ENSMUST00000102504]
[ENSMUST00000102505]
[ENSMUST00000108431]
[ENSMUST00000136935]
|
| AlphaFold |
Q9WTI7 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000069057
AA Change: L222*
|
| SMART Domains |
Protein: ENSMUSP00000070388
Gene: ENSMUSG00000017774
AA Change: L222*
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
5 |
697 |
N/A |
SMART |
|
IQ
|
698 |
720 |
3.85e-3 |
SMART |
|
IQ
|
721 |
743 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
751 |
780 |
5e-9 |
BLAST |
|
low complexity region
|
804 |
815 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
838 |
1024 |
1.9e-41 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000102504
AA Change: L222*
|
| SMART Domains |
Protein: ENSMUSP00000099562
Gene: ENSMUSG00000017774
AA Change: L222*
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
5 |
697 |
N/A |
SMART |
|
IQ
|
698 |
720 |
3.85e-3 |
SMART |
|
IQ
|
721 |
743 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
751 |
780 |
5e-9 |
BLAST |
|
low complexity region
|
804 |
815 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
838 |
1024 |
1.9e-41 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000102505
AA Change: L257*
|
| SMART Domains |
Protein: ENSMUSP00000099563
Gene: ENSMUSG00000017774
AA Change: L257*
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
40 |
732 |
N/A |
SMART |
|
IQ
|
733 |
755 |
3.85e-3 |
SMART |
|
IQ
|
756 |
778 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
786 |
815 |
6e-9 |
BLAST |
|
low complexity region
|
839 |
850 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
874 |
1052 |
2.9e-29 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000108431
AA Change: L238*
|
| SMART Domains |
Protein: ENSMUSP00000104069
Gene: ENSMUSG00000017774
AA Change: L238*
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
21 |
713 |
N/A |
SMART |
|
IQ
|
714 |
736 |
3.85e-3 |
SMART |
|
IQ
|
737 |
759 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
767 |
796 |
5e-9 |
BLAST |
|
low complexity region
|
820 |
831 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
854 |
1040 |
3.3e-41 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000136935
|
| SMART Domains |
Protein: ENSMUSP00000121267
Gene: ENSMUSG00000017774
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
18 |
N/A |
INTRINSIC |
|
PDB:4BYF|C
|
39 |
80 |
5e-21 |
PDB |
|
Blast:MYSc
|
43 |
80 |
9e-19 |
BLAST |
|
SCOP:d1lkxa_
|
50 |
80 |
3e-7 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000148659
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151174
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.7%
|
| Validation Efficiency |
93% (89/96) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The protein functions in intracellular vesicle transport to the plasma membrane. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-in (Y61G) mutation that sensitizes to N6-modified ADP analogs display altered fast adaption in vestibular hair cells. Mice homozygous for a nuclear isoform-specifc knock-out allele exhibit minor changes in bone marrow density and red blood cells. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8a |
A |
G |
11: 109,962,341 (GRCm39) |
V503A |
possibly damaging |
Het |
| Agps |
T |
A |
2: 75,722,199 (GRCm39) |
F463Y |
possibly damaging |
Het |
| Ajm1 |
G |
A |
2: 25,469,759 (GRCm39) |
R51C |
possibly damaging |
Het |
| Amigo3 |
A |
T |
9: 107,930,734 (GRCm39) |
L52F |
probably damaging |
Het |
| Anapc1 |
T |
C |
2: 128,527,980 (GRCm39) |
|
probably benign |
Het |
| Ankrd36 |
G |
T |
11: 5,540,870 (GRCm39) |
C312F |
possibly damaging |
Het |
| Asic2 |
A |
C |
11: 80,862,318 (GRCm39) |
D226E |
probably benign |
Het |
| Atp8b2 |
T |
A |
3: 89,864,374 (GRCm39) |
Q197L |
probably damaging |
Het |
| C2cd3 |
A |
G |
7: 100,092,642 (GRCm39) |
Y495C |
probably damaging |
Het |
| Ccdc51 |
A |
G |
9: 108,919,978 (GRCm39) |
T125A |
probably benign |
Het |
| Ccser1 |
A |
G |
6: 61,288,485 (GRCm39) |
Y216C |
possibly damaging |
Het |
| Cimap1b |
A |
G |
15: 89,263,326 (GRCm39) |
I19T |
probably damaging |
Het |
| Cntfr |
A |
T |
4: 41,663,282 (GRCm39) |
I175N |
possibly damaging |
Het |
| Cox10 |
G |
A |
11: 63,854,989 (GRCm39) |
R431W |
probably benign |
Het |
| Cubn |
T |
C |
2: 13,319,578 (GRCm39) |
T2881A |
possibly damaging |
Het |
| Cyp2d9 |
T |
A |
15: 82,336,774 (GRCm39) |
V41E |
probably damaging |
Het |
| Dmrtb1 |
C |
T |
4: 107,540,986 (GRCm39) |
G125D |
probably benign |
Het |
| Dscaml1 |
C |
T |
9: 45,581,404 (GRCm39) |
R408C |
probably damaging |
Het |
| Duox2 |
A |
T |
2: 122,115,397 (GRCm39) |
S1052T |
probably benign |
Het |
| Ecm1 |
A |
G |
3: 95,645,273 (GRCm39) |
|
probably benign |
Het |
| Edrf1 |
G |
T |
7: 133,260,339 (GRCm39) |
M83I |
probably damaging |
Het |
| Epb41l1 |
T |
A |
2: 156,371,344 (GRCm39) |
M727K |
probably benign |
Het |
| Exosc9 |
T |
C |
3: 36,607,984 (GRCm39) |
V64A |
probably damaging |
Het |
| Ezh2 |
A |
T |
6: 47,517,630 (GRCm39) |
I564N |
probably damaging |
Het |
| Fam89b |
C |
A |
19: 5,779,482 (GRCm39) |
R25L |
probably damaging |
Het |
| Fgr |
C |
T |
4: 132,714,602 (GRCm39) |
T98M |
probably damaging |
Het |
| Fhip2b |
T |
A |
14: 70,825,727 (GRCm39) |
D351V |
probably damaging |
Het |
| Gapvd1 |
A |
G |
2: 34,581,193 (GRCm39) |
S1089P |
probably damaging |
Het |
| Gbp5 |
A |
T |
3: 142,213,837 (GRCm39) |
I544F |
possibly damaging |
Het |
| Gli2 |
C |
A |
1: 118,910,318 (GRCm39) |
|
probably benign |
Het |
| Gm9934 |
A |
G |
7: 92,702,192 (GRCm39) |
|
noncoding transcript |
Het |
| Greb1 |
A |
T |
12: 16,731,357 (GRCm39) |
D1660E |
probably benign |
Het |
| Gtf2i |
T |
A |
5: 134,272,414 (GRCm39) |
N750I |
possibly damaging |
Het |
| H2-DMb2 |
G |
C |
17: 34,367,698 (GRCm39) |
D171H |
probably damaging |
Het |
| Il11ra1 |
A |
G |
4: 41,768,187 (GRCm39) |
E366G |
probably damaging |
Het |
| Itga2b |
A |
G |
11: 102,351,582 (GRCm39) |
F581S |
probably damaging |
Het |
| Itsn2 |
T |
A |
12: 4,677,892 (GRCm39) |
M83K |
probably damaging |
Het |
| Kif27 |
G |
A |
13: 58,492,191 (GRCm39) |
T316M |
probably damaging |
Het |
| Lad1 |
A |
T |
1: 135,753,531 (GRCm39) |
Q26L |
probably damaging |
Het |
| Lrrn3 |
T |
A |
12: 41,502,442 (GRCm39) |
H625L |
probably benign |
Het |
| Mast1 |
A |
G |
8: 85,655,875 (GRCm39) |
V155A |
probably benign |
Het |
| Mast3 |
G |
A |
8: 71,238,864 (GRCm39) |
T480M |
probably damaging |
Het |
| Mpc1 |
C |
T |
17: 8,512,377 (GRCm39) |
|
probably benign |
Het |
| Mycbp2 |
T |
A |
14: 103,457,380 (GRCm39) |
M1606L |
probably benign |
Het |
| Nanog |
T |
G |
6: 122,688,550 (GRCm39) |
S44A |
possibly damaging |
Het |
| Neb |
T |
C |
2: 52,039,165 (GRCm39) |
Q6958R |
probably benign |
Het |
| Ngef |
C |
T |
1: 87,405,283 (GRCm39) |
R709H |
probably damaging |
Het |
| Nr1d1 |
A |
G |
11: 98,661,471 (GRCm39) |
V265A |
probably benign |
Het |
| Nr3c2 |
A |
G |
8: 77,634,872 (GRCm39) |
|
probably null |
Het |
| Olfm5 |
A |
G |
7: 103,809,685 (GRCm39) |
S164P |
probably benign |
Het |
| Parvb |
T |
C |
15: 84,188,106 (GRCm39) |
|
probably null |
Het |
| Pde4dip |
G |
T |
3: 97,674,400 (GRCm39) |
A172D |
probably damaging |
Het |
| Phf2 |
A |
G |
13: 48,957,079 (GRCm39) |
L1096P |
probably damaging |
Het |
| Pik3r6 |
T |
A |
11: 68,420,720 (GRCm39) |
V155E |
probably damaging |
Het |
| Pinx1 |
T |
G |
14: 64,109,820 (GRCm39) |
V124G |
probably damaging |
Het |
| Poglut1 |
A |
G |
16: 38,355,119 (GRCm39) |
Y236H |
probably damaging |
Het |
| Pou4f2 |
T |
A |
8: 79,163,030 (GRCm39) |
M2L |
unknown |
Het |
| Ppfia2 |
G |
C |
10: 106,597,978 (GRCm39) |
L180F |
probably damaging |
Het |
| Pramel26 |
C |
T |
4: 143,538,519 (GRCm39) |
E151K |
probably damaging |
Het |
| Prkaca |
A |
G |
8: 84,717,499 (GRCm39) |
N209S |
probably benign |
Het |
| Ring1 |
G |
A |
17: 34,242,361 (GRCm39) |
P49S |
probably damaging |
Het |
| Rnf20 |
T |
A |
4: 49,633,412 (GRCm39) |
|
probably null |
Het |
| Rnf25 |
G |
A |
1: 74,633,099 (GRCm39) |
R418C |
probably damaging |
Het |
| Ryr1 |
G |
T |
7: 28,808,707 (GRCm39) |
P462Q |
probably damaging |
Het |
| Serpinb3d |
A |
G |
1: 107,006,008 (GRCm39) |
F360S |
probably damaging |
Het |
| Setd7 |
T |
C |
3: 51,428,843 (GRCm39) |
E329G |
probably damaging |
Het |
| Slco2b1 |
C |
T |
7: 99,320,156 (GRCm39) |
|
probably null |
Het |
| Snap91 |
G |
A |
9: 86,655,654 (GRCm39) |
T844I |
possibly damaging |
Het |
| Snhg5 |
C |
T |
9: 88,404,424 (GRCm39) |
|
noncoding transcript |
Het |
| Son |
T |
A |
16: 91,455,756 (GRCm39) |
V1501E |
probably damaging |
Het |
| Syncrip |
T |
A |
9: 88,361,905 (GRCm39) |
E70V |
probably damaging |
Het |
| Tas2r125 |
A |
G |
6: 132,886,750 (GRCm39) |
D46G |
probably damaging |
Het |
| Tmem115 |
G |
A |
9: 107,412,156 (GRCm39) |
R160Q |
probably benign |
Het |
| Trerf1 |
G |
A |
17: 47,630,581 (GRCm39) |
|
noncoding transcript |
Het |
| Tut7 |
A |
G |
13: 59,920,698 (GRCm39) |
|
probably benign |
Het |
| Uggt2 |
A |
T |
14: 119,266,466 (GRCm39) |
|
probably null |
Het |
| Ush2a |
G |
T |
1: 188,282,076 (GRCm39) |
V1864F |
probably benign |
Het |
| Xkr4 |
A |
T |
1: 3,286,714 (GRCm39) |
V492D |
probably damaging |
Het |
| Zfp646 |
T |
A |
7: 127,482,649 (GRCm39) |
S1609T |
possibly damaging |
Het |
| Zfp65 |
A |
T |
13: 67,856,477 (GRCm39) |
H277Q |
probably damaging |
Het |
| Zfp69 |
A |
G |
4: 120,791,614 (GRCm39) |
S176P |
probably damaging |
Het |
| Zfp747 |
C |
T |
7: 126,974,971 (GRCm39) |
A10T |
probably damaging |
Het |
| Zfp850 |
T |
C |
7: 27,684,411 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Myo1c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01346:Myo1c
|
APN |
11 |
75,563,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02054:Myo1c
|
APN |
11 |
75,551,962 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02115:Myo1c
|
APN |
11 |
75,552,417 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02375:Myo1c
|
APN |
11 |
75,552,400 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02878:Myo1c
|
APN |
11 |
75,559,859 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03008:Myo1c
|
APN |
11 |
75,549,240 (GRCm39) |
missense |
probably benign |
0.13 |
|
Sweeper
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R0070:Myo1c
|
UTSW |
11 |
75,551,076 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0070:Myo1c
|
UTSW |
11 |
75,551,076 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0138:Myo1c
|
UTSW |
11 |
75,551,827 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0200:Myo1c
|
UTSW |
11 |
75,563,008 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0227:Myo1c
|
UTSW |
11 |
75,549,520 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0257:Myo1c
|
UTSW |
11 |
75,556,342 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0513:Myo1c
|
UTSW |
11 |
75,556,657 (GRCm39) |
splice site |
probably null |
|
|
R0587:Myo1c
|
UTSW |
11 |
75,548,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0667:Myo1c
|
UTSW |
11 |
75,559,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Myo1c
|
UTSW |
11 |
75,560,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Myo1c
|
UTSW |
11 |
75,560,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1793:Myo1c
|
UTSW |
11 |
75,548,415 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1922:Myo1c
|
UTSW |
11 |
75,559,055 (GRCm39) |
missense |
probably benign |
|
|
R2000:Myo1c
|
UTSW |
11 |
75,561,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3983:Myo1c
|
UTSW |
11 |
75,552,325 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4583:Myo1c
|
UTSW |
11 |
75,562,688 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4599:Myo1c
|
UTSW |
11 |
75,559,019 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4671:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4682:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4708:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4709:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4742:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4888:Myo1c
|
UTSW |
11 |
75,560,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Myo1c
|
UTSW |
11 |
75,547,135 (GRCm39) |
start codon destroyed |
probably null |
|
|
R4934:Myo1c
|
UTSW |
11 |
75,562,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4971:Myo1c
|
UTSW |
11 |
75,562,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5319:Myo1c
|
UTSW |
11 |
75,552,852 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5589:Myo1c
|
UTSW |
11 |
75,548,414 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R5624:Myo1c
|
UTSW |
11 |
75,553,461 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5756:Myo1c
|
UTSW |
11 |
75,549,240 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5959:Myo1c
|
UTSW |
11 |
75,548,345 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6160:Myo1c
|
UTSW |
11 |
75,541,568 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6559:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6568:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6569:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6574:Myo1c
|
UTSW |
11 |
75,547,124 (GRCm39) |
start gained |
probably benign |
|
|
R6579:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6580:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6583:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6640:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6642:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6643:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6679:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6680:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6687:Myo1c
|
UTSW |
11 |
75,563,027 (GRCm39) |
missense |
probably benign |
|
|
R6695:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6696:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6700:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6712:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6713:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6715:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R7081:Myo1c
|
UTSW |
11 |
75,551,789 (GRCm39) |
missense |
probably benign |
|
|
R7265:Myo1c
|
UTSW |
11 |
75,560,616 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7397:Myo1c
|
UTSW |
11 |
75,562,068 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7586:Myo1c
|
UTSW |
11 |
75,548,345 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7714:Myo1c
|
UTSW |
11 |
75,549,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Myo1c
|
UTSW |
11 |
75,546,942 (GRCm39) |
unclassified |
probably benign |
|
|
R8341:Myo1c
|
UTSW |
11 |
75,562,253 (GRCm39) |
missense |
probably benign |
0.42 |
|
R8466:Myo1c
|
UTSW |
11 |
75,549,213 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8771:Myo1c
|
UTSW |
11 |
75,556,709 (GRCm39) |
missense |
probably benign |
|
|
R8829:Myo1c
|
UTSW |
11 |
75,561,072 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8832:Myo1c
|
UTSW |
11 |
75,561,072 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9243:Myo1c
|
UTSW |
11 |
75,541,437 (GRCm39) |
unclassified |
probably benign |
|
|
R9489:Myo1c
|
UTSW |
11 |
75,559,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9605:Myo1c
|
UTSW |
11 |
75,559,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9744:Myo1c
|
UTSW |
11 |
75,562,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9782:Myo1c
|
UTSW |
11 |
75,549,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGACAGCTTCTTTCCCCTGG -3'
(R):5'- TGAAGTCAATGACGGACAGC -3'
Sequencing Primer
(F):5'- GTCCAGCTGACCATCCCTG -3'
(R):5'- AATGACGGACAGCGCCTTC -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation