Incidental Mutation 'R4770:Itsn2'
| ID |
367433 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Itsn2
|
| Ensembl Gene |
ENSMUSG00000020640 |
| Gene Name |
intersectin 2 |
| Synonyms |
Sh3d1B, Sh3p18, Ese2, Eh domain, SH3 domain regulator of endocytosis 2 |
| MMRRC Submission |
042410-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4770 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
4642792-4763952 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 4677892 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 83
(M83K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000151663
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000062580]
[ENSMUST00000218402]
[ENSMUST00000219007]
[ENSMUST00000220311]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
unknown
Transcript: ENSMUST00000062580
AA Change: M83K
|
| SMART Domains |
Protein: ENSMUSP00000052758
Gene: ENSMUSG00000020640
AA Change: M83K
| Domain | Start | End | E-Value | Type |
|---|
|
EH
|
15 |
109 |
8.44e-41 |
SMART |
|
EFh
|
58 |
86 |
7.18e-3 |
SMART |
|
low complexity region
|
156 |
169 |
N/A |
INTRINSIC |
|
low complexity region
|
215 |
231 |
N/A |
INTRINSIC |
|
EH
|
238 |
333 |
4.06e-43 |
SMART |
|
EFh
|
282 |
310 |
6.16e-2 |
SMART |
|
coiled coil region
|
366 |
462 |
N/A |
INTRINSIC |
|
coiled coil region
|
516 |
556 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
715 |
N/A |
INTRINSIC |
|
SH3
|
721 |
778 |
2.65e-21 |
SMART |
|
low complexity region
|
791 |
811 |
N/A |
INTRINSIC |
|
SH3
|
855 |
909 |
8.83e-18 |
SMART |
|
SH3
|
945 |
999 |
9.1e-20 |
SMART |
|
SH3
|
1017 |
1077 |
1.55e-13 |
SMART |
|
SH3
|
1091 |
1146 |
7.22e-23 |
SMART |
|
RhoGEF
|
1174 |
1355 |
1.93e-56 |
SMART |
|
PH
|
1396 |
1507 |
1.16e-9 |
SMART |
|
C2
|
1531 |
1628 |
3.96e-19 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000217882
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000217942
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000217981
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218072
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000218402
AA Change: M83K
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000219007
AA Change: M83K
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000220311
AA Change: M83K
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219832
|
| Meta Mutation Damage Score |
0.9090 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.7%
|
| Validation Efficiency |
93% (89/96) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. [provided by RefSeq, Jan 2017]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal brain morphology and function and behavior. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8a |
A |
G |
11: 109,962,341 (GRCm39) |
V503A |
possibly damaging |
Het |
| Agps |
T |
A |
2: 75,722,199 (GRCm39) |
F463Y |
possibly damaging |
Het |
| Ajm1 |
G |
A |
2: 25,469,759 (GRCm39) |
R51C |
possibly damaging |
Het |
| Amigo3 |
A |
T |
9: 107,930,734 (GRCm39) |
L52F |
probably damaging |
Het |
| Anapc1 |
T |
C |
2: 128,527,980 (GRCm39) |
|
probably benign |
Het |
| Ankrd36 |
G |
T |
11: 5,540,870 (GRCm39) |
C312F |
possibly damaging |
Het |
| Asic2 |
A |
C |
11: 80,862,318 (GRCm39) |
D226E |
probably benign |
Het |
| Atp8b2 |
T |
A |
3: 89,864,374 (GRCm39) |
Q197L |
probably damaging |
Het |
| C2cd3 |
A |
G |
7: 100,092,642 (GRCm39) |
Y495C |
probably damaging |
Het |
| Ccdc51 |
A |
G |
9: 108,919,978 (GRCm39) |
T125A |
probably benign |
Het |
| Ccser1 |
A |
G |
6: 61,288,485 (GRCm39) |
Y216C |
possibly damaging |
Het |
| Cimap1b |
A |
G |
15: 89,263,326 (GRCm39) |
I19T |
probably damaging |
Het |
| Cntfr |
A |
T |
4: 41,663,282 (GRCm39) |
I175N |
possibly damaging |
Het |
| Cox10 |
G |
A |
11: 63,854,989 (GRCm39) |
R431W |
probably benign |
Het |
| Cubn |
T |
C |
2: 13,319,578 (GRCm39) |
T2881A |
possibly damaging |
Het |
| Cyp2d9 |
T |
A |
15: 82,336,774 (GRCm39) |
V41E |
probably damaging |
Het |
| Dmrtb1 |
C |
T |
4: 107,540,986 (GRCm39) |
G125D |
probably benign |
Het |
| Dscaml1 |
C |
T |
9: 45,581,404 (GRCm39) |
R408C |
probably damaging |
Het |
| Duox2 |
A |
T |
2: 122,115,397 (GRCm39) |
S1052T |
probably benign |
Het |
| Ecm1 |
A |
G |
3: 95,645,273 (GRCm39) |
|
probably benign |
Het |
| Edrf1 |
G |
T |
7: 133,260,339 (GRCm39) |
M83I |
probably damaging |
Het |
| Epb41l1 |
T |
A |
2: 156,371,344 (GRCm39) |
M727K |
probably benign |
Het |
| Exosc9 |
T |
C |
3: 36,607,984 (GRCm39) |
V64A |
probably damaging |
Het |
| Ezh2 |
A |
T |
6: 47,517,630 (GRCm39) |
I564N |
probably damaging |
Het |
| Fam89b |
C |
A |
19: 5,779,482 (GRCm39) |
R25L |
probably damaging |
Het |
| Fgr |
C |
T |
4: 132,714,602 (GRCm39) |
T98M |
probably damaging |
Het |
| Fhip2b |
T |
A |
14: 70,825,727 (GRCm39) |
D351V |
probably damaging |
Het |
| Gapvd1 |
A |
G |
2: 34,581,193 (GRCm39) |
S1089P |
probably damaging |
Het |
| Gbp5 |
A |
T |
3: 142,213,837 (GRCm39) |
I544F |
possibly damaging |
Het |
| Gli2 |
C |
A |
1: 118,910,318 (GRCm39) |
|
probably benign |
Het |
| Gm9934 |
A |
G |
7: 92,702,192 (GRCm39) |
|
noncoding transcript |
Het |
| Greb1 |
A |
T |
12: 16,731,357 (GRCm39) |
D1660E |
probably benign |
Het |
| Gtf2i |
T |
A |
5: 134,272,414 (GRCm39) |
N750I |
possibly damaging |
Het |
| H2-DMb2 |
G |
C |
17: 34,367,698 (GRCm39) |
D171H |
probably damaging |
Het |
| Il11ra1 |
A |
G |
4: 41,768,187 (GRCm39) |
E366G |
probably damaging |
Het |
| Itga2b |
A |
G |
11: 102,351,582 (GRCm39) |
F581S |
probably damaging |
Het |
| Kif27 |
G |
A |
13: 58,492,191 (GRCm39) |
T316M |
probably damaging |
Het |
| Lad1 |
A |
T |
1: 135,753,531 (GRCm39) |
Q26L |
probably damaging |
Het |
| Lrrn3 |
T |
A |
12: 41,502,442 (GRCm39) |
H625L |
probably benign |
Het |
| Mast1 |
A |
G |
8: 85,655,875 (GRCm39) |
V155A |
probably benign |
Het |
| Mast3 |
G |
A |
8: 71,238,864 (GRCm39) |
T480M |
probably damaging |
Het |
| Mpc1 |
C |
T |
17: 8,512,377 (GRCm39) |
|
probably benign |
Het |
| Mycbp2 |
T |
A |
14: 103,457,380 (GRCm39) |
M1606L |
probably benign |
Het |
| Myo1c |
T |
A |
11: 75,551,139 (GRCm39) |
L238* |
probably null |
Het |
| Nanog |
T |
G |
6: 122,688,550 (GRCm39) |
S44A |
possibly damaging |
Het |
| Neb |
T |
C |
2: 52,039,165 (GRCm39) |
Q6958R |
probably benign |
Het |
| Ngef |
C |
T |
1: 87,405,283 (GRCm39) |
R709H |
probably damaging |
Het |
| Nr1d1 |
A |
G |
11: 98,661,471 (GRCm39) |
V265A |
probably benign |
Het |
| Nr3c2 |
A |
G |
8: 77,634,872 (GRCm39) |
|
probably null |
Het |
| Olfm5 |
A |
G |
7: 103,809,685 (GRCm39) |
S164P |
probably benign |
Het |
| Parvb |
T |
C |
15: 84,188,106 (GRCm39) |
|
probably null |
Het |
| Pde4dip |
G |
T |
3: 97,674,400 (GRCm39) |
A172D |
probably damaging |
Het |
| Phf2 |
A |
G |
13: 48,957,079 (GRCm39) |
L1096P |
probably damaging |
Het |
| Pik3r6 |
T |
A |
11: 68,420,720 (GRCm39) |
V155E |
probably damaging |
Het |
| Pinx1 |
T |
G |
14: 64,109,820 (GRCm39) |
V124G |
probably damaging |
Het |
| Poglut1 |
A |
G |
16: 38,355,119 (GRCm39) |
Y236H |
probably damaging |
Het |
| Pou4f2 |
T |
A |
8: 79,163,030 (GRCm39) |
M2L |
unknown |
Het |
| Ppfia2 |
G |
C |
10: 106,597,978 (GRCm39) |
L180F |
probably damaging |
Het |
| Pramel26 |
C |
T |
4: 143,538,519 (GRCm39) |
E151K |
probably damaging |
Het |
| Prkaca |
A |
G |
8: 84,717,499 (GRCm39) |
N209S |
probably benign |
Het |
| Ring1 |
G |
A |
17: 34,242,361 (GRCm39) |
P49S |
probably damaging |
Het |
| Rnf20 |
T |
A |
4: 49,633,412 (GRCm39) |
|
probably null |
Het |
| Rnf25 |
G |
A |
1: 74,633,099 (GRCm39) |
R418C |
probably damaging |
Het |
| Ryr1 |
G |
T |
7: 28,808,707 (GRCm39) |
P462Q |
probably damaging |
Het |
| Serpinb3d |
A |
G |
1: 107,006,008 (GRCm39) |
F360S |
probably damaging |
Het |
| Setd7 |
T |
C |
3: 51,428,843 (GRCm39) |
E329G |
probably damaging |
Het |
| Slco2b1 |
C |
T |
7: 99,320,156 (GRCm39) |
|
probably null |
Het |
| Snap91 |
G |
A |
9: 86,655,654 (GRCm39) |
T844I |
possibly damaging |
Het |
| Snhg5 |
C |
T |
9: 88,404,424 (GRCm39) |
|
noncoding transcript |
Het |
| Son |
T |
A |
16: 91,455,756 (GRCm39) |
V1501E |
probably damaging |
Het |
| Syncrip |
T |
A |
9: 88,361,905 (GRCm39) |
E70V |
probably damaging |
Het |
| Tas2r125 |
A |
G |
6: 132,886,750 (GRCm39) |
D46G |
probably damaging |
Het |
| Tmem115 |
G |
A |
9: 107,412,156 (GRCm39) |
R160Q |
probably benign |
Het |
| Trerf1 |
G |
A |
17: 47,630,581 (GRCm39) |
|
noncoding transcript |
Het |
| Tut7 |
A |
G |
13: 59,920,698 (GRCm39) |
|
probably benign |
Het |
| Uggt2 |
A |
T |
14: 119,266,466 (GRCm39) |
|
probably null |
Het |
| Ush2a |
G |
T |
1: 188,282,076 (GRCm39) |
V1864F |
probably benign |
Het |
| Xkr4 |
A |
T |
1: 3,286,714 (GRCm39) |
V492D |
probably damaging |
Het |
| Zfp646 |
T |
A |
7: 127,482,649 (GRCm39) |
S1609T |
possibly damaging |
Het |
| Zfp65 |
A |
T |
13: 67,856,477 (GRCm39) |
H277Q |
probably damaging |
Het |
| Zfp69 |
A |
G |
4: 120,791,614 (GRCm39) |
S176P |
probably damaging |
Het |
| Zfp747 |
C |
T |
7: 126,974,971 (GRCm39) |
A10T |
probably damaging |
Het |
| Zfp850 |
T |
C |
7: 27,684,411 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Itsn2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00341:Itsn2
|
APN |
12 |
4,708,027 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL00647:Itsn2
|
APN |
12 |
4,663,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL00933:Itsn2
|
APN |
12 |
4,757,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01686:Itsn2
|
APN |
12 |
4,686,693 (GRCm39) |
splice site |
probably benign |
|
|
IGL01873:Itsn2
|
APN |
12 |
4,682,366 (GRCm39) |
splice site |
probably benign |
|
|
IGL02200:Itsn2
|
APN |
12 |
4,686,632 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02280:Itsn2
|
APN |
12 |
4,758,961 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02388:Itsn2
|
APN |
12 |
4,679,557 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02938:Itsn2
|
APN |
12 |
4,747,216 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Gopher
|
UTSW |
12 |
4,756,983 (GRCm39) |
nonsense |
probably null |
|
|
inversus
|
UTSW |
12 |
4,689,670 (GRCm39) |
nonsense |
probably null |
|
|
Liberator
|
UTSW |
12 |
4,716,176 (GRCm39) |
nonsense |
probably null |
|
|
rolled
|
UTSW |
12 |
4,684,792 (GRCm39) |
nonsense |
probably null |
|
|
Stratofortress
|
UTSW |
12 |
4,674,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Underground
|
UTSW |
12 |
4,751,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Vole
|
UTSW |
12 |
4,723,420 (GRCm39) |
nonsense |
probably null |
|
|
R0101:Itsn2
|
UTSW |
12 |
4,683,058 (GRCm39) |
unclassified |
probably benign |
|
|
R0268:Itsn2
|
UTSW |
12 |
4,750,333 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0584:Itsn2
|
UTSW |
12 |
4,747,180 (GRCm39) |
missense |
probably benign |
|
|
R0604:Itsn2
|
UTSW |
12 |
4,708,189 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0639:Itsn2
|
UTSW |
12 |
4,762,556 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0738:Itsn2
|
UTSW |
12 |
4,685,681 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1132:Itsn2
|
UTSW |
12 |
4,708,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1163:Itsn2
|
UTSW |
12 |
4,762,009 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1169:Itsn2
|
UTSW |
12 |
4,689,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1258:Itsn2
|
UTSW |
12 |
4,723,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1297:Itsn2
|
UTSW |
12 |
4,750,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1423:Itsn2
|
UTSW |
12 |
4,723,572 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1572:Itsn2
|
UTSW |
12 |
4,700,044 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1601:Itsn2
|
UTSW |
12 |
4,708,452 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1628:Itsn2
|
UTSW |
12 |
4,679,652 (GRCm39) |
missense |
probably benign |
|
|
R1650:Itsn2
|
UTSW |
12 |
4,687,767 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1752:Itsn2
|
UTSW |
12 |
4,761,950 (GRCm39) |
splice site |
probably null |
|
|
R1758:Itsn2
|
UTSW |
12 |
4,708,160 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1942:Itsn2
|
UTSW |
12 |
4,689,670 (GRCm39) |
nonsense |
probably null |
|
|
R1976:Itsn2
|
UTSW |
12 |
4,722,733 (GRCm39) |
splice site |
probably benign |
|
|
R2000:Itsn2
|
UTSW |
12 |
4,716,176 (GRCm39) |
nonsense |
probably null |
|
|
R2060:Itsn2
|
UTSW |
12 |
4,677,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2119:Itsn2
|
UTSW |
12 |
4,757,025 (GRCm39) |
missense |
probably benign |
0.32 |
|
R2168:Itsn2
|
UTSW |
12 |
4,683,044 (GRCm39) |
unclassified |
probably benign |
|
|
R2394:Itsn2
|
UTSW |
12 |
4,757,005 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R2860:Itsn2
|
UTSW |
12 |
4,750,315 (GRCm39) |
splice site |
probably benign |
|
|
R2861:Itsn2
|
UTSW |
12 |
4,750,315 (GRCm39) |
splice site |
probably benign |
|
|
R2900:Itsn2
|
UTSW |
12 |
4,680,713 (GRCm39) |
unclassified |
probably benign |
|
|
R2991:Itsn2
|
UTSW |
12 |
4,708,474 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3087:Itsn2
|
UTSW |
12 |
4,716,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3881:Itsn2
|
UTSW |
12 |
4,684,546 (GRCm39) |
unclassified |
probably benign |
|
|
R4022:Itsn2
|
UTSW |
12 |
4,674,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4332:Itsn2
|
UTSW |
12 |
4,762,611 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4657:Itsn2
|
UTSW |
12 |
4,763,197 (GRCm39) |
makesense |
probably null |
|
|
R4727:Itsn2
|
UTSW |
12 |
4,757,660 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4745:Itsn2
|
UTSW |
12 |
4,711,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4905:Itsn2
|
UTSW |
12 |
4,684,583 (GRCm39) |
unclassified |
probably benign |
|
|
R5269:Itsn2
|
UTSW |
12 |
4,683,553 (GRCm39) |
unclassified |
probably benign |
|
|
R5314:Itsn2
|
UTSW |
12 |
4,677,960 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5345:Itsn2
|
UTSW |
12 |
4,722,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5399:Itsn2
|
UTSW |
12 |
4,703,535 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5566:Itsn2
|
UTSW |
12 |
4,676,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5725:Itsn2
|
UTSW |
12 |
4,680,767 (GRCm39) |
unclassified |
probably benign |
|
|
R5773:Itsn2
|
UTSW |
12 |
4,757,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6116:Itsn2
|
UTSW |
12 |
4,679,939 (GRCm39) |
unclassified |
probably benign |
|
|
R6254:Itsn2
|
UTSW |
12 |
4,674,982 (GRCm39) |
splice site |
probably null |
|
|
R6325:Itsn2
|
UTSW |
12 |
4,756,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6361:Itsn2
|
UTSW |
12 |
4,679,655 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6456:Itsn2
|
UTSW |
12 |
4,679,923 (GRCm39) |
unclassified |
probably benign |
|
|
R6494:Itsn2
|
UTSW |
12 |
4,684,792 (GRCm39) |
nonsense |
probably null |
|
|
R6854:Itsn2
|
UTSW |
12 |
4,702,382 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6941:Itsn2
|
UTSW |
12 |
4,679,641 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6961:Itsn2
|
UTSW |
12 |
4,723,420 (GRCm39) |
nonsense |
probably null |
|
|
R7326:Itsn2
|
UTSW |
12 |
4,682,985 (GRCm39) |
missense |
unknown |
|
|
R7387:Itsn2
|
UTSW |
12 |
4,689,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7465:Itsn2
|
UTSW |
12 |
4,756,983 (GRCm39) |
nonsense |
probably null |
|
|
R7471:Itsn2
|
UTSW |
12 |
4,758,198 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7814:Itsn2
|
UTSW |
12 |
4,708,561 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7854:Itsn2
|
UTSW |
12 |
4,751,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7879:Itsn2
|
UTSW |
12 |
4,751,265 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7990:Itsn2
|
UTSW |
12 |
4,685,629 (GRCm39) |
missense |
unknown |
|
|
R8009:Itsn2
|
UTSW |
12 |
4,714,553 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8115:Itsn2
|
UTSW |
12 |
4,723,602 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8143:Itsn2
|
UTSW |
12 |
4,683,003 (GRCm39) |
missense |
unknown |
|
|
R8248:Itsn2
|
UTSW |
12 |
4,712,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8735:Itsn2
|
UTSW |
12 |
4,721,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8748:Itsn2
|
UTSW |
12 |
4,751,337 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9018:Itsn2
|
UTSW |
12 |
4,708,091 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9386:Itsn2
|
UTSW |
12 |
4,679,730 (GRCm39) |
missense |
unknown |
|
|
R9681:Itsn2
|
UTSW |
12 |
4,683,499 (GRCm39) |
missense |
unknown |
|
|
Z1088:Itsn2
|
UTSW |
12 |
4,762,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTCTACATGTGAATGCTTTGCC -3'
(R):5'- CCAGACAGGGACACTTAGCTATG -3'
Sequencing Primer
(F):5'- CATGTGAATGCTTTGCCATTGTTTTC -3'
(R):5'- AACTTGGAAGTCTAGGGATTGTC -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation