Mutagenetix > Incidental Mutation

Incidental Mutation 'R4772:Baz2b'

367578

Institutional Source

Beutler Lab

Gene Symbol

Baz2b

Ensembl Gene

ENSMUSG00000026987

Gene Name

bromodomain adjacent to zinc finger domain, 2B

Synonyms

D2Ertd794e, 5830435C13Rik

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.321) question?

Stock #

R4772 (G1)

Quality Score

219

Status

Validated

Chromosome

Chromosomal Location

59899363-60209839 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 59958451 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Serine at position 697 (R697S)

Ref Sequence

ENSEMBL: ENSMUSP00000108169 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090925] [ENSMUST00000112550]

AlphaFold

A2AUY4

Predicted Effect

probably damaging
Transcript: ENSMUST00000090925
AA Change: R697S

PolyPhen 2 Score 0.961 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000088443
Gene: ENSMUSG00000026987
AA Change: R697S

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	742	1e-12	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000112550
AA Change: R697S

PolyPhen 2 Score 0.961 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000108169
Gene: ENSMUSG00000026987
AA Change: R697S

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	741	3.4e-13	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Pfam:WHIM3	1638	1676	5.1e-14	PFAM
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000135722

Meta Mutation Damage Score

0.3104

Coding Region Coverage

1x: 99.1%
3x: 98.5%
10x: 96.8%
20x: 94.1%

Validation Efficiency

95% (74/78)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 74 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca13	T	A	11: 9,315,339 (GRCm38)		probably null	Het
Adamts19	A	G	18: 58,837,776 (GRCm38)	Q144R	possibly damaging	Het
Adgrb3	C	A	1: 25,531,875 (GRCm38)	C507F	probably damaging	Het
Atg9b	T	C	5: 24,385,239 (GRCm38)	*923W	probably null	Het
Atp13a4	T	C	16: 29,420,835 (GRCm38)		probably benign	Het
Bicdl1	A	G	5: 115,661,478 (GRCm38)	I184T	probably benign	Het
Bpifb4	C	T	2: 153,942,983 (GRCm38)	L204F	possibly damaging	Het
Cep120	C	T	18: 53,718,489 (GRCm38)	R577Q	probably damaging	Het
Cplx4	T	C	18: 65,969,977 (GRCm38)	E24G	possibly damaging	Het
Dcxr	T	C	11: 120,726,097 (GRCm38)	T147A	probably benign	Het
Dnajc10	C	A	2: 80,340,526 (GRCm38)	H454N	probably damaging	Het
Dsp	G	T	13: 38,167,528 (GRCm38)	G108*	probably null	Het
Entpd6	T	A	2: 150,767,094 (GRCm38)	I366K	probably damaging	Het
Fam111a	A	G	19: 12,587,693 (GRCm38)	K269E	probably benign	Het
Grid2ip	T	G	5: 143,375,700 (GRCm38)	V222G	possibly damaging	Het
Hmcn2	T	G	2: 31,445,314 (GRCm38)	V4421G	probably benign	Het
Ifi207	T	C	1: 173,727,687 (GRCm38)	T817A	probably damaging	Het
Irak2	A	T	6: 113,693,722 (GRCm38)	E533V	probably damaging	Het
Katnip	A	G	7: 125,865,351 (GRCm38)	S1297G	probably damaging	Het
Kbtbd6	T	C	14: 79,452,156 (GRCm38)	F97S	probably damaging	Het
Kctd14	A	T	7: 97,457,676 (GRCm38)	E99V	probably damaging	Het
Klhl10	A	T	11: 100,447,731 (GRCm38)	Y432F	probably benign	Het
Lrrc49	T	C	9: 60,685,052 (GRCm38)	N53S	possibly damaging	Het
Mief2	T	A	11: 60,730,462 (GRCm38)		probably benign	Het
Mog	A	T	17: 37,023,157 (GRCm38)	S15T	unknown	Het
Mpi	T	C	9: 57,544,898 (GRCm38)	D365G	probably damaging	Het
Mpp7	A	G	18: 7,379,983 (GRCm38)		probably null	Het
Nes	A	G	3: 87,976,179 (GRCm38)	T582A	probably benign	Het
Nlrp14	A	G	7: 107,181,186 (GRCm38)	D5G	probably benign	Het
Nr1i3	C	T	1: 171,217,150 (GRCm38)	T218I	probably damaging	Het
Nup43	C	T	10: 7,678,669 (GRCm38)	R339*	probably null	Het
Nup58	T	A	14: 60,220,022 (GRCm38)	R577S	probably benign	Het
Olfr908	C	T	9: 38,516,601 (GRCm38)		probably benign	Het
Or4l15	AAATTTGAA	AAA	14: 49,960,995 (GRCm38)		probably benign	Het
Or52n4b	T	A	7: 108,544,885 (GRCm38)	M120K	probably damaging	Het
Or5d35	T	A	2: 88,024,863 (GRCm38)	I47K	probably damaging	Het
Or6c38	A	T	10: 129,093,668 (GRCm38)	V102D	possibly damaging	Het
Or9g20	G	A	2: 85,799,994 (GRCm38)	S92F	probably damaging	Het
Orc1	T	C	4: 108,579,568 (GRCm38)		probably benign	Het
Pax6	C	A	2: 105,696,502 (GRCm38)	P251Q	probably benign	Het
Phactr3	C	T	2: 178,283,936 (GRCm38)	R330W	probably damaging	Het
Phldb1	G	A	9: 44,711,027 (GRCm38)	R81W	probably damaging	Het
Pip5k1c	C	T	10: 81,315,940 (GRCm38)	P656L	probably benign	Het
Pkn3	T	G	2: 30,084,680 (GRCm38)		probably null	Het
Plcb2	T	A	2: 118,713,134 (GRCm38)	H752L	probably benign	Het
Plch1	G	A	3: 63,753,325 (GRCm38)	T291M	probably damaging	Het
Plekhg1	A	T	10: 3,873,127 (GRCm38)	M32L	probably benign	Het
Plekhg1	A	T	10: 3,873,130 (GRCm38)	T33S	probably damaging	Het
Plk4	A	G	3: 40,805,190 (GRCm38)	T174A	probably damaging	Het
Ppip5k2	C	A	1: 97,721,067 (GRCm38)		probably benign	Het
Prl2a1	G	A	13: 27,804,978 (GRCm38)	V29M	probably benign	Het
R3hcc1l	T	C	19: 42,583,557 (GRCm38)		probably benign	Het
Rasa3	C	T	8: 13,598,289 (GRCm38)	G125D	probably damaging	Het
Sema3f	A	T	9: 107,689,720 (GRCm38)	Y136*	probably null	Het
Slc13a5	T	A	11: 72,250,846 (GRCm38)		probably null	Het
Slc16a1	T	C	3: 104,653,564 (GRCm38)	V395A	possibly damaging	Het
Sparcl1	C	T	5: 104,088,490 (GRCm38)	A466T	probably benign	Het
Srrm1	G	A	4: 135,342,379 (GRCm38)		probably benign	Het
Styxl1	G	A	5: 135,768,901 (GRCm38)	R50*	probably null	Het
Tex264	T	A	9: 106,673,702 (GRCm38)	I99F	possibly damaging	Het
Tgtp2	T	C	11: 49,058,984 (GRCm38)	T254A	probably damaging	Het
Tmem245	A	C	4: 56,937,989 (GRCm38)		probably null	Het
Tnik	A	T	3: 28,607,210 (GRCm38)	T587S	probably benign	Het
Tpr	T	G	1: 150,413,113 (GRCm38)	S648A	possibly damaging	Het
Ttn	T	C	2: 76,765,969 (GRCm38)	E18454G	probably damaging	Het
Utp20	A	C	10: 88,809,935 (GRCm38)	H527Q	probably benign	Het
Vmn1r1	A	T	1: 182,157,546 (GRCm38)	S185T	probably benign	Het
Vps54	C	T	11: 21,312,952 (GRCm38)	H680Y	probably damaging	Het
Vwa5b2	A	G	16: 20,600,803 (GRCm38)		probably null	Het
Wscd1	T	C	11: 71,771,976 (GRCm38)		probably null	Het
Zbtb41	C	T	1: 139,447,414 (GRCm38)	P871S	probably damaging	Het
Zcchc4	T	C	5: 52,796,207 (GRCm38)	L186P	possibly damaging	Het
Zdhhc13	A	G	7: 48,799,873 (GRCm38)	Y73C	probably benign	Het
Zfp12	A	G	5: 143,240,000 (GRCm38)	E21G	probably damaging	Het

Other mutations in Baz2b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00430:Baz2b	APN	2	59,912,795 (GRCm38)	missense	probably benign	0.02
IGL00476:Baz2b	APN	2	59,913,739 (GRCm38)	missense	probably benign	0.06
IGL00489:Baz2b	APN	2	59,957,675 (GRCm38)	nonsense	probably null
IGL00514:Baz2b	APN	2	59,962,477 (GRCm38)	missense	probably benign	0.11
IGL00678:Baz2b	APN	2	60,006,183 (GRCm38)	missense	unknown
IGL01348:Baz2b	APN	2	59,933,687 (GRCm38)	missense	possibly damaging	0.95
IGL01354:Baz2b	APN	2	59,968,889 (GRCm38)	missense	probably benign	0.18
IGL01924:Baz2b	APN	2	59,935,271 (GRCm38)	missense	probably damaging	1.00
IGL02125:Baz2b	APN	2	59,968,640 (GRCm38)	missense	probably benign	0.12
IGL02314:Baz2b	APN	2	59,962,227 (GRCm38)	missense	probably benign
IGL02370:Baz2b	APN	2	59,923,589 (GRCm38)	missense	possibly damaging	0.77
IGL02473:Baz2b	APN	2	59,960,063 (GRCm38)	missense	probably benign	0.40
IGL02499:Baz2b	APN	2	59,901,496 (GRCm38)	missense	possibly damaging	0.60
IGL02609:Baz2b	APN	2	59,917,369 (GRCm38)	missense	possibly damaging	0.77
IGL02705:Baz2b	APN	2	59,948,260 (GRCm38)	missense	possibly damaging	0.92
IGL02711:Baz2b	APN	2	59,917,505 (GRCm38)	unclassified	probably benign
IGL02716:Baz2b	APN	2	59,962,524 (GRCm38)	missense	possibly damaging	0.53
IGL02724:Baz2b	APN	2	59,977,374 (GRCm38)	missense	possibly damaging	0.70
IGL02750:Baz2b	APN	2	59,968,658 (GRCm38)	missense	possibly damaging	0.73
IGL02869:Baz2b	APN	2	59,977,528 (GRCm38)	missense	probably benign	0.00
IGL02886:Baz2b	APN	2	59,957,743 (GRCm38)	splice site	probably null
IGL02892:Baz2b	APN	2	59,900,736 (GRCm38)	missense	probably damaging	1.00
IGL03132:Baz2b	APN	2	59,907,753 (GRCm38)	splice site	probably benign
IGL03183:Baz2b	APN	2	59,903,296 (GRCm38)	missense	probably benign	0.10
IGL03197:Baz2b	APN	2	59,901,554 (GRCm38)	missense	possibly damaging	0.74
R0054:Baz2b	UTSW	2	59,932,166 (GRCm38)	missense	probably damaging	1.00
R0054:Baz2b	UTSW	2	59,932,166 (GRCm38)	missense	probably damaging	1.00
R0122:Baz2b	UTSW	2	59,913,619 (GRCm38)	splice site	probably null
R0136:Baz2b	UTSW	2	59,901,954 (GRCm38)	missense	probably benign	0.22
R0144:Baz2b	UTSW	2	59,907,495 (GRCm38)	missense	probably damaging	0.98
R0403:Baz2b	UTSW	2	59,969,377 (GRCm38)	missense	possibly damaging	0.70
R0498:Baz2b	UTSW	2	59,901,996 (GRCm38)	unclassified	probably benign
R0528:Baz2b	UTSW	2	59,936,739 (GRCm38)	missense	probably damaging	1.00
R1025:Baz2b	UTSW	2	59,962,482 (GRCm38)	missense	probably benign	0.06
R1470:Baz2b	UTSW	2	59,978,546 (GRCm38)	missense	possibly damaging	0.53
R1470:Baz2b	UTSW	2	59,978,546 (GRCm38)	missense	possibly damaging	0.53
R1510:Baz2b	UTSW	2	59,922,209 (GRCm38)	missense	probably damaging	1.00
R1511:Baz2b	UTSW	2	59,962,024 (GRCm38)	missense	probably benign	0.12
R1514:Baz2b	UTSW	2	59,962,326 (GRCm38)	missense	probably benign	0.13
R1519:Baz2b	UTSW	2	59,948,254 (GRCm38)	missense	possibly damaging	0.50
R1523:Baz2b	UTSW	2	59,968,637 (GRCm38)	missense	possibly damaging	0.47
R1630:Baz2b	UTSW	2	60,006,130 (GRCm38)	missense	unknown
R1641:Baz2b	UTSW	2	59,912,890 (GRCm38)	missense	probably damaging	0.99
R1674:Baz2b	UTSW	2	59,912,992 (GRCm38)	missense	possibly damaging	0.53
R1778:Baz2b	UTSW	2	60,006,136 (GRCm38)	missense	unknown
R1826:Baz2b	UTSW	2	59,968,733 (GRCm38)	missense	probably benign	0.12
R1835:Baz2b	UTSW	2	59,901,819 (GRCm38)	missense	probably benign	0.02
R1954:Baz2b	UTSW	2	59,968,743 (GRCm38)	missense	probably benign	0.12
R1981:Baz2b	UTSW	2	59,923,680 (GRCm38)	missense	possibly damaging	0.95
R2029:Baz2b	UTSW	2	59,912,723 (GRCm38)	unclassified	probably benign
R2567:Baz2b	UTSW	2	59,913,911 (GRCm38)	missense	possibly damaging	0.82
R2842:Baz2b	UTSW	2	59,913,004 (GRCm38)	missense	probably benign	0.27
R2848:Baz2b	UTSW	2	59,924,666 (GRCm38)	missense	possibly damaging	0.64
R3809:Baz2b	UTSW	2	59,968,896 (GRCm38)	missense	probably benign	0.12
R3935:Baz2b	UTSW	2	59,912,761 (GRCm38)	missense	possibly damaging	0.81
R3936:Baz2b	UTSW	2	59,912,761 (GRCm38)	missense	possibly damaging	0.81
R4072:Baz2b	UTSW	2	59,912,573 (GRCm38)	splice site	probably null
R4182:Baz2b	UTSW	2	60,098,457 (GRCm38)	intron	probably benign
R4255:Baz2b	UTSW	2	59,920,572 (GRCm38)	unclassified	probably benign
R4359:Baz2b	UTSW	2	59,901,613 (GRCm38)	missense	possibly damaging	0.87
R4716:Baz2b	UTSW	2	59,969,255 (GRCm38)	missense	probably benign	0.06
R4743:Baz2b	UTSW	2	59,913,911 (GRCm38)	missense	probably benign	0.01
R4858:Baz2b	UTSW	2	59,907,743 (GRCm38)	missense	probably benign
R4868:Baz2b	UTSW	2	59,924,882 (GRCm38)	missense	possibly damaging	0.65
R4872:Baz2b	UTSW	2	59,942,759 (GRCm38)	splice site	probably null
R4889:Baz2b	UTSW	2	59,936,726 (GRCm38)	missense	probably damaging	1.00
R4890:Baz2b	UTSW	2	59,926,039 (GRCm38)	missense	probably damaging	0.99
R4914:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R4915:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R4918:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R5027:Baz2b	UTSW	2	60,098,644 (GRCm38)	intron	probably benign
R5031:Baz2b	UTSW	2	59,912,807 (GRCm38)	missense	probably benign	0.00
R5082:Baz2b	UTSW	2	59,901,491 (GRCm38)	nonsense	probably null
R5133:Baz2b	UTSW	2	59,962,024 (GRCm38)	missense	probably benign	0.12
R5276:Baz2b	UTSW	2	59,962,614 (GRCm38)	missense	probably benign	0.40
R5279:Baz2b	UTSW	2	59,932,152 (GRCm38)	missense	probably damaging	1.00
R5294:Baz2b	UTSW	2	59,978,602 (GRCm38)	missense	probably benign	0.11
R5447:Baz2b	UTSW	2	59,913,988 (GRCm38)	missense	probably damaging	0.99
R5903:Baz2b	UTSW	2	59,959,889 (GRCm38)	missense	probably damaging	0.99
R5910:Baz2b	UTSW	2	59,977,426 (GRCm38)	missense	possibly damaging	0.88
R6140:Baz2b	UTSW	2	59,912,527 (GRCm38)	missense	probably damaging	0.99
R6195:Baz2b	UTSW	2	59,907,511 (GRCm38)	missense	possibly damaging	0.89
R6199:Baz2b	UTSW	2	59,978,675 (GRCm38)	missense	probably benign	0.00
R6208:Baz2b	UTSW	2	59,924,806 (GRCm38)	missense	probably damaging	1.00
R6233:Baz2b	UTSW	2	59,907,511 (GRCm38)	missense	possibly damaging	0.89
R6276:Baz2b	UTSW	2	59,948,223 (GRCm38)	missense	probably damaging	1.00
R6324:Baz2b	UTSW	2	59,906,948 (GRCm38)	missense	probably damaging	1.00
R6490:Baz2b	UTSW	2	59,901,729 (GRCm38)	missense	probably damaging	1.00
R6578:Baz2b	UTSW	2	59,969,279 (GRCm38)	missense	possibly damaging	0.47
R6720:Baz2b	UTSW	2	59,924,890 (GRCm38)	missense	probably damaging	1.00
R6760:Baz2b	UTSW	2	59,962,432 (GRCm38)	missense	probably benign	0.40
R6836:Baz2b	UTSW	2	59,917,425 (GRCm38)	missense	probably damaging	1.00
R6859:Baz2b	UTSW	2	59,901,530 (GRCm38)	missense	probably benign	0.01
R6880:Baz2b	UTSW	2	59,912,939 (GRCm38)	missense	probably damaging	0.99
R6916:Baz2b	UTSW	2	59,968,776 (GRCm38)	missense	probably benign
R6978:Baz2b	UTSW	2	59,907,715 (GRCm38)	missense	possibly damaging	0.84
R7037:Baz2b	UTSW	2	59,933,670 (GRCm38)	critical splice donor site	probably null
R7112:Baz2b	UTSW	2	59,962,184 (GRCm38)	missense	possibly damaging	0.53
R7117:Baz2b	UTSW	2	59,912,497 (GRCm38)	missense
R7198:Baz2b	UTSW	2	59,962,206 (GRCm38)	missense	probably benign	0.00
R7270:Baz2b	UTSW	2	59,962,492 (GRCm38)	missense	possibly damaging	0.96
R7282:Baz2b	UTSW	2	59,920,437 (GRCm38)	missense	probably benign	0.17
R7464:Baz2b	UTSW	2	59,977,448 (GRCm38)	missense	possibly damaging	0.53
R7609:Baz2b	UTSW	2	59,962,473 (GRCm38)	missense	probably benign	0.40
R7703:Baz2b	UTSW	2	59,917,425 (GRCm38)	missense	probably damaging	1.00
R7850:Baz2b	UTSW	2	59,936,716 (GRCm38)	missense	probably damaging	0.98
R7851:Baz2b	UTSW	2	59,936,716 (GRCm38)	missense	probably damaging	0.98
R7988:Baz2b	UTSW	2	59,962,141 (GRCm38)	missense	possibly damaging	0.53
R8079:Baz2b	UTSW	2	59,900,768 (GRCm38)	missense	probably damaging	1.00
R8084:Baz2b	UTSW	2	59,962,236 (GRCm38)	missense	probably benign
R8343:Baz2b	UTSW	2	59,901,514 (GRCm38)	missense	probably damaging	1.00
R8348:Baz2b	UTSW	2	59,911,793 (GRCm38)	missense
R8438:Baz2b	UTSW	2	59,917,484 (GRCm38)	nonsense	probably null
R8448:Baz2b	UTSW	2	59,911,793 (GRCm38)	missense
R8511:Baz2b	UTSW	2	59,901,814 (GRCm38)	missense	probably benign
R8893:Baz2b	UTSW	2	59,924,805 (GRCm38)	missense	probably damaging	0.96
R8947:Baz2b	UTSW	2	59,948,239 (GRCm38)	missense	probably benign	0.06
R8998:Baz2b	UTSW	2	59,969,264 (GRCm38)	missense	probably benign	0.02
R9241:Baz2b	UTSW	2	59,913,649 (GRCm38)	missense	probably benign	0.01
R9245:Baz2b	UTSW	2	59,912,987 (GRCm38)	missense	probably benign
R9577:Baz2b	UTSW	2	59,978,687 (GRCm38)	missense	probably benign	0.06
R9581:Baz2b	UTSW	2	59,968,956 (GRCm38)	missense	probably benign
R9601:Baz2b	UTSW	2	59,901,503 (GRCm38)	missense	possibly damaging	0.66
R9613:Baz2b	UTSW	2	59,901,480 (GRCm38)	missense	probably benign	0.09
R9639:Baz2b	UTSW	2	59,901,484 (GRCm38)	missense	probably benign	0.01
X0011:Baz2b	UTSW	2	59,977,361 (GRCm38)	missense	possibly damaging	0.53
X0053:Baz2b	UTSW	2	59,900,675 (GRCm38)	missense	probably damaging	1.00
X0064:Baz2b	UTSW	2	59,969,282 (GRCm38)	missense	probably benign
Z1088:Baz2b	UTSW	2	59,960,015 (GRCm38)	missense	probably damaging	1.00
Z1177:Baz2b	UTSW	2	59,977,520 (GRCm38)	missense	probably benign	0.01
Z1188:Baz2b	UTSW	2	59,977,405 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- TCTCTGAACCCTGCATCAAC -3'
(R):5'- GTGTCTGTCATAGGCCAGAAG -3'

Sequencing Primer
(F):5'- TGAACCCTGCATCAACTTCATC -3'
(R):5'- ACGTATCTTATGTAGTATGCTCAGC -3'

Posted On

2015-12-29