Incidental Mutation 'R4773:Plxnb2'
| ID |
367716 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb2
|
| Ensembl Gene |
ENSMUSG00000036606 |
| Gene Name |
plexin B2 |
| Synonyms |
1110007H23Rik, Debt |
| MMRRC Submission |
042411-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.943)
|
| Stock # |
R4773 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
89039752-89064960 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 89051150 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 356
(H356Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104955
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000060808]
[ENSMUST00000109331]
|
| AlphaFold |
B2RXS4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000060808
AA Change: H356Q
PolyPhen 2
Score 0.059 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000051731
Gene: ENSMUSG00000036606
AA Change: H356Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
34 |
452 |
8.87e-92 |
SMART |
|
PSI
|
470 |
521 |
1.94e-10 |
SMART |
|
PSI
|
616 |
669 |
4.09e-1 |
SMART |
|
PSI
|
761 |
804 |
7.02e-8 |
SMART |
|
IPT
|
805 |
896 |
8.14e-19 |
SMART |
|
IPT
|
897 |
983 |
1.1e-15 |
SMART |
|
IPT
|
985 |
1096 |
5.06e-6 |
SMART |
|
Pfam:Plexin_cytopl
|
1275 |
1809 |
1.6e-225 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109331
AA Change: H356Q
PolyPhen 2
Score 0.059 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000104955
Gene: ENSMUSG00000036606
AA Change: H356Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
34 |
452 |
8.87e-92 |
SMART |
|
PSI
|
470 |
521 |
1.94e-10 |
SMART |
|
PSI
|
616 |
669 |
4.09e-1 |
SMART |
|
PSI
|
761 |
804 |
7.02e-8 |
SMART |
|
IPT
|
805 |
896 |
8.14e-19 |
SMART |
|
IPT
|
897 |
983 |
1.1e-15 |
SMART |
|
IPT
|
985 |
1096 |
5.06e-6 |
SMART |
|
Pfam:Plexin_cytopl
|
1274 |
1809 |
4.4e-251 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000131062
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197760
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.2%
|
| Validation Efficiency |
100% (89/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Homozygotes for a targeted mutation of this gene die perinatally of exencephaly or survive and seem normal despite severe abnormalities in cerebellar layering and foliation; the external granule cell layer is disorganized due to continued proliferation and migration of differentiated granule cells. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9230009I02Rik |
A |
G |
11: 50,982,089 (GRCm39) |
|
noncoding transcript |
Het |
| Actl7b |
T |
C |
4: 56,740,972 (GRCm39) |
I129V |
probably benign |
Het |
| Adipor2 |
A |
G |
6: 119,336,047 (GRCm39) |
L225P |
probably benign |
Het |
| Arhgap25 |
A |
G |
6: 87,473,053 (GRCm39) |
F35L |
probably benign |
Het |
| Asah2 |
A |
T |
19: 32,030,258 (GRCm39) |
M138K |
probably damaging |
Het |
| Asxl1 |
T |
A |
2: 153,243,905 (GRCm39) |
M1486K |
probably damaging |
Het |
| B4galt4 |
T |
A |
16: 38,572,658 (GRCm39) |
S114R |
probably benign |
Het |
| Brpf3 |
T |
G |
17: 29,040,233 (GRCm39) |
S885A |
probably benign |
Het |
| Cacna1g |
G |
T |
11: 94,302,298 (GRCm39) |
H1944N |
possibly damaging |
Het |
| Cby2 |
T |
A |
14: 75,820,546 (GRCm39) |
Y393F |
probably damaging |
Het |
| Ccdc110 |
G |
A |
8: 46,396,245 (GRCm39) |
C712Y |
probably damaging |
Het |
| Ccdc175 |
A |
T |
12: 72,182,822 (GRCm39) |
I399N |
probably damaging |
Het |
| Cct8l1 |
A |
T |
5: 25,722,754 (GRCm39) |
T490S |
probably benign |
Het |
| Cd109 |
CATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
9: 78,619,782 (GRCm39) |
|
probably benign |
Het |
| Copa |
A |
G |
1: 171,932,787 (GRCm39) |
N371D |
probably damaging |
Het |
| Cpeb1 |
A |
T |
7: 81,005,695 (GRCm39) |
H381Q |
probably benign |
Het |
| Cyp2d40 |
T |
A |
15: 82,645,763 (GRCm39) |
I81F |
possibly damaging |
Het |
| Dscc1 |
A |
T |
15: 54,943,654 (GRCm39) |
D405E |
probably benign |
Het |
| Ece1 |
A |
G |
4: 137,672,464 (GRCm39) |
D369G |
probably benign |
Het |
| Exd2 |
T |
C |
12: 80,522,592 (GRCm39) |
V17A |
possibly damaging |
Het |
| Fam111a |
A |
T |
19: 12,565,772 (GRCm39) |
N507I |
possibly damaging |
Het |
| Flnc |
T |
C |
6: 29,445,038 (GRCm39) |
V719A |
possibly damaging |
Het |
| Fscb |
C |
T |
12: 64,520,464 (GRCm39) |
G334D |
probably damaging |
Het |
| Glud1 |
T |
C |
14: 34,043,782 (GRCm39) |
|
probably null |
Het |
| Gm8126 |
T |
A |
14: 43,119,072 (GRCm39) |
Y180* |
probably null |
Het |
| Grip2 |
G |
A |
6: 91,759,413 (GRCm39) |
P347L |
possibly damaging |
Het |
| H1f3 |
T |
C |
13: 23,739,576 (GRCm39) |
S105P |
probably damaging |
Het |
| H60b |
C |
T |
10: 22,164,644 (GRCm39) |
|
probably benign |
Het |
| Iqca1l |
A |
G |
5: 24,755,596 (GRCm39) |
|
probably null |
Het |
| Itga6 |
T |
C |
2: 71,652,788 (GRCm39) |
V217A |
probably benign |
Het |
| Kndc1 |
G |
A |
7: 139,503,946 (GRCm39) |
W1083* |
probably null |
Het |
| Limch1 |
A |
T |
5: 67,184,850 (GRCm39) |
D613V |
probably damaging |
Het |
| Lpl |
T |
A |
8: 69,349,403 (GRCm39) |
C310S |
probably damaging |
Het |
| Marchf1 |
T |
A |
8: 66,839,876 (GRCm39) |
C220S |
probably benign |
Het |
| Mbd5 |
A |
C |
2: 49,164,623 (GRCm39) |
H308P |
probably damaging |
Het |
| Med13 |
T |
C |
11: 86,167,746 (GRCm39) |
D2003G |
probably damaging |
Het |
| Mettl16 |
T |
A |
11: 74,708,127 (GRCm39) |
V442D |
possibly damaging |
Het |
| Mstn |
A |
T |
1: 53,101,267 (GRCm39) |
T115S |
probably benign |
Het |
| Mtcl2 |
G |
T |
2: 156,872,489 (GRCm39) |
Q953K |
probably benign |
Het |
| Nfil3 |
A |
G |
13: 53,122,050 (GRCm39) |
S285P |
probably damaging |
Het |
| Odad4 |
C |
A |
11: 100,440,742 (GRCm39) |
N74K |
probably benign |
Het |
| Or10j3 |
A |
C |
1: 173,031,796 (GRCm39) |
Y291S |
probably damaging |
Het |
| Or51a24 |
A |
G |
7: 103,733,502 (GRCm39) |
S262P |
probably damaging |
Het |
| Otof |
A |
G |
5: 30,552,026 (GRCm39) |
V321A |
probably benign |
Het |
| Pcdha8 |
G |
T |
18: 37,127,626 (GRCm39) |
A703S |
probably damaging |
Het |
| Pcdhb18 |
A |
G |
18: 37,623,507 (GRCm39) |
Y279C |
probably damaging |
Het |
| Pdgfa |
T |
C |
5: 138,979,051 (GRCm39) |
D51G |
probably benign |
Het |
| Pdzd8 |
A |
G |
19: 59,289,292 (GRCm39) |
Y703H |
probably damaging |
Het |
| Pecr |
G |
T |
1: 72,306,594 (GRCm39) |
P229Q |
probably damaging |
Het |
| Phkg1 |
G |
T |
5: 129,902,114 (GRCm39) |
|
probably null |
Het |
| Polr1b |
T |
C |
2: 128,947,248 (GRCm39) |
I191T |
probably benign |
Het |
| Ppp4r3a |
A |
G |
12: 101,049,026 (GRCm39) |
L35P |
possibly damaging |
Het |
| Rasa2 |
C |
T |
9: 96,426,470 (GRCm39) |
G792D |
probably benign |
Het |
| Rps11-ps4 |
T |
C |
12: 51,344,406 (GRCm39) |
|
noncoding transcript |
Het |
| Sema3g |
A |
G |
14: 30,942,666 (GRCm39) |
D89G |
probably benign |
Het |
| Shroom3 |
G |
T |
5: 93,090,945 (GRCm39) |
V1151F |
probably damaging |
Het |
| Slfn8 |
A |
G |
11: 82,908,219 (GRCm39) |
V108A |
probably damaging |
Het |
| Smg9 |
T |
A |
7: 24,107,019 (GRCm39) |
M221K |
possibly damaging |
Het |
| Sos1 |
A |
G |
17: 80,705,660 (GRCm39) |
S1304P |
probably damaging |
Het |
| Sqle |
C |
A |
15: 59,189,688 (GRCm39) |
A110E |
possibly damaging |
Het |
| Stab2 |
G |
A |
10: 86,743,235 (GRCm39) |
Q1154* |
probably null |
Het |
| Taf4b |
A |
G |
18: 14,937,577 (GRCm39) |
T217A |
probably benign |
Het |
| Tex15 |
T |
C |
8: 34,072,760 (GRCm39) |
V2769A |
probably benign |
Het |
| Tmem156 |
A |
T |
5: 65,237,502 (GRCm39) |
C53S |
probably damaging |
Het |
| Tmtc3 |
T |
A |
10: 100,293,001 (GRCm39) |
K452N |
possibly damaging |
Het |
| Tns2 |
C |
T |
15: 102,017,369 (GRCm39) |
R281C |
probably damaging |
Het |
| Tph1 |
T |
C |
7: 46,306,376 (GRCm39) |
E195G |
probably damaging |
Het |
| Trpc6 |
T |
A |
9: 8,609,852 (GRCm39) |
Y107N |
possibly damaging |
Het |
| Tsga10 |
G |
A |
1: 37,874,606 (GRCm39) |
T93I |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,571,778 (GRCm39) |
N26372Y |
probably damaging |
Het |
| Tubd1 |
T |
C |
11: 86,446,128 (GRCm39) |
L256P |
possibly damaging |
Het |
| Txnrd2 |
C |
G |
16: 18,259,569 (GRCm39) |
A126G |
probably benign |
Het |
| Vmn1r210 |
T |
G |
13: 23,011,374 (GRCm39) |
K304T |
probably benign |
Het |
| Vps25 |
T |
C |
11: 101,149,655 (GRCm39) |
S160P |
probably benign |
Het |
| Vrk3 |
T |
A |
7: 44,424,900 (GRCm39) |
D438E |
probably benign |
Het |
| Vwa5b1 |
A |
G |
4: 138,309,066 (GRCm39) |
L708P |
probably benign |
Het |
| Washc3 |
C |
T |
10: 88,055,124 (GRCm39) |
Q105* |
probably null |
Het |
| Wdr83os |
T |
A |
8: 85,807,410 (GRCm39) |
|
probably benign |
Het |
| Wwc1 |
T |
C |
11: 35,758,123 (GRCm39) |
H741R |
probably benign |
Het |
| Zan |
T |
C |
5: 137,434,575 (GRCm39) |
|
probably benign |
Het |
| Zdhhc4 |
A |
T |
5: 143,311,931 (GRCm39) |
L14I |
possibly damaging |
Het |
| Zfp568 |
T |
A |
7: 29,697,195 (GRCm39) |
D38E |
probably damaging |
Het |
|
| Other mutations in Plxnb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00546:Plxnb2
|
APN |
15 |
89,046,569 (GRCm39) |
splice site |
probably benign |
|
|
IGL01574:Plxnb2
|
APN |
15 |
89,046,886 (GRCm39) |
splice site |
probably null |
|
|
IGL01695:Plxnb2
|
APN |
15 |
89,041,417 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01763:Plxnb2
|
APN |
15 |
89,046,184 (GRCm39) |
splice site |
probably null |
|
|
IGL01921:Plxnb2
|
APN |
15 |
89,048,474 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02129:Plxnb2
|
APN |
15 |
89,044,613 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02153:Plxnb2
|
APN |
15 |
89,050,016 (GRCm39) |
nonsense |
probably null |
|
|
IGL02637:Plxnb2
|
APN |
15 |
89,048,260 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL02892:Plxnb2
|
APN |
15 |
89,045,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03108:Plxnb2
|
APN |
15 |
89,042,234 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03115:Plxnb2
|
APN |
15 |
89,046,641 (GRCm39) |
splice site |
probably benign |
|
|
P0040:Plxnb2
|
UTSW |
15 |
89,047,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0022:Plxnb2
|
UTSW |
15 |
89,047,479 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0095:Plxnb2
|
UTSW |
15 |
89,049,534 (GRCm39) |
missense |
probably benign |
|
|
R0103:Plxnb2
|
UTSW |
15 |
89,045,972 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0544:Plxnb2
|
UTSW |
15 |
89,042,816 (GRCm39) |
splice site |
probably benign |
|
|
R0671:Plxnb2
|
UTSW |
15 |
89,042,184 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1279:Plxnb2
|
UTSW |
15 |
89,046,524 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1530:Plxnb2
|
UTSW |
15 |
89,051,395 (GRCm39) |
missense |
probably benign |
|
|
R1542:Plxnb2
|
UTSW |
15 |
89,050,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1610:Plxnb2
|
UTSW |
15 |
89,042,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1686:Plxnb2
|
UTSW |
15 |
89,046,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1702:Plxnb2
|
UTSW |
15 |
89,046,187 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1996:Plxnb2
|
UTSW |
15 |
89,042,971 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1997:Plxnb2
|
UTSW |
15 |
89,042,971 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2031:Plxnb2
|
UTSW |
15 |
89,047,013 (GRCm39) |
nonsense |
probably null |
|
|
R2049:Plxnb2
|
UTSW |
15 |
89,043,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2072:Plxnb2
|
UTSW |
15 |
89,042,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2076:Plxnb2
|
UTSW |
15 |
89,042,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Plxnb2
|
UTSW |
15 |
89,040,765 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2418:Plxnb2
|
UTSW |
15 |
89,045,272 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2419:Plxnb2
|
UTSW |
15 |
89,045,272 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R3752:Plxnb2
|
UTSW |
15 |
89,041,458 (GRCm39) |
splice site |
probably benign |
|
|
R3825:Plxnb2
|
UTSW |
15 |
89,050,602 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4154:Plxnb2
|
UTSW |
15 |
89,043,845 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4197:Plxnb2
|
UTSW |
15 |
89,041,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4385:Plxnb2
|
UTSW |
15 |
89,044,826 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4434:Plxnb2
|
UTSW |
15 |
89,047,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4678:Plxnb2
|
UTSW |
15 |
89,045,131 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4717:Plxnb2
|
UTSW |
15 |
89,041,622 (GRCm39) |
nonsense |
probably null |
|
|
R4905:Plxnb2
|
UTSW |
15 |
89,041,614 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5368:Plxnb2
|
UTSW |
15 |
89,043,796 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5418:Plxnb2
|
UTSW |
15 |
89,050,694 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5484:Plxnb2
|
UTSW |
15 |
89,048,412 (GRCm39) |
splice site |
probably null |
|
|
R5520:Plxnb2
|
UTSW |
15 |
89,051,746 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5566:Plxnb2
|
UTSW |
15 |
89,048,223 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5568:Plxnb2
|
UTSW |
15 |
89,041,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5619:Plxnb2
|
UTSW |
15 |
89,047,012 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5685:Plxnb2
|
UTSW |
15 |
89,051,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5688:Plxnb2
|
UTSW |
15 |
89,042,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5809:Plxnb2
|
UTSW |
15 |
89,051,774 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R5813:Plxnb2
|
UTSW |
15 |
89,044,962 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5866:Plxnb2
|
UTSW |
15 |
89,051,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6016:Plxnb2
|
UTSW |
15 |
89,045,225 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R6117:Plxnb2
|
UTSW |
15 |
89,042,203 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6187:Plxnb2
|
UTSW |
15 |
89,051,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6260:Plxnb2
|
UTSW |
15 |
89,049,494 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6263:Plxnb2
|
UTSW |
15 |
89,046,189 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6269:Plxnb2
|
UTSW |
15 |
89,044,916 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6351:Plxnb2
|
UTSW |
15 |
89,041,973 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6522:Plxnb2
|
UTSW |
15 |
89,048,629 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6856:Plxnb2
|
UTSW |
15 |
89,048,523 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6930:Plxnb2
|
UTSW |
15 |
89,044,592 (GRCm39) |
missense |
probably benign |
|
|
R7354:Plxnb2
|
UTSW |
15 |
89,049,928 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7513:Plxnb2
|
UTSW |
15 |
89,042,525 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7522:Plxnb2
|
UTSW |
15 |
89,045,977 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7730:Plxnb2
|
UTSW |
15 |
89,046,533 (GRCm39) |
missense |
probably benign |
|
|
R7766:Plxnb2
|
UTSW |
15 |
89,045,474 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7781:Plxnb2
|
UTSW |
15 |
89,041,225 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8126:Plxnb2
|
UTSW |
15 |
89,047,506 (GRCm39) |
missense |
probably benign |
|
|
R8131:Plxnb2
|
UTSW |
15 |
89,042,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8372:Plxnb2
|
UTSW |
15 |
89,042,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8736:Plxnb2
|
UTSW |
15 |
89,046,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8772:Plxnb2
|
UTSW |
15 |
89,046,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9022:Plxnb2
|
UTSW |
15 |
89,048,471 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9044:Plxnb2
|
UTSW |
15 |
89,044,566 (GRCm39) |
splice site |
probably benign |
|
|
R9253:Plxnb2
|
UTSW |
15 |
89,052,015 (GRCm39) |
missense |
probably benign |
|
|
R9398:Plxnb2
|
UTSW |
15 |
89,045,122 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9562:Plxnb2
|
UTSW |
15 |
89,050,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9568:Plxnb2
|
UTSW |
15 |
89,045,160 (GRCm39) |
nonsense |
probably null |
|
|
R9613:Plxnb2
|
UTSW |
15 |
89,048,496 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0027:Plxnb2
|
UTSW |
15 |
89,044,916 (GRCm39) |
missense |
probably benign |
0.18 |
|
Z1177:Plxnb2
|
UTSW |
15 |
89,043,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCACGACTGCCCAGTGGATAG -3'
(R):5'- TGTCTTCAGCAGAGATGGC -3'
Sequencing Primer
(F):5'- TGGCACCCTGTGGATCAC -3'
(R):5'- CTTCAGCAGAGATGGCCGGAG -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation