Incidental Mutation 'R4776:Il1rap'
| ID |
367971 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Il1rap
|
| Ensembl Gene |
ENSMUSG00000022514 |
| Gene Name |
interleukin 1 receptor accessory protein |
| Synonyms |
IL-1RAcP, 6430709H04Rik, IL-1R AcP |
| MMRRC Submission |
042413-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4776 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
26400454-26548867 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 26511549 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 198
(S198G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133904
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000023156]
[ENSMUST00000096129]
[ENSMUST00000166294]
[ENSMUST00000174171]
[ENSMUST00000174202]
|
| AlphaFold |
Q61730 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000023156
AA Change: S198G
PolyPhen 2
Score 0.301 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000023156
Gene: ENSMUSG00000022514
AA Change: S198G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
IG
|
251 |
350 |
1.46e-5 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
TIR
|
404 |
549 |
5.29e-36 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000096129
AA Change: S198G
PolyPhen 2
Score 0.301 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000093843
Gene: ENSMUSG00000022514
AA Change: S198G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
IG
|
251 |
350 |
1.46e-5 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
TIR
|
404 |
547 |
1.38e-25 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166294
AA Change: S198G
PolyPhen 2
Score 0.353 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000128100
Gene: ENSMUSG00000022514
AA Change: S198G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
IG
|
251 |
350 |
1.46e-5 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
TIR
|
404 |
547 |
1.38e-25 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000174171
AA Change: S198G
PolyPhen 2
Score 0.568 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000133904
Gene: ENSMUSG00000022514
AA Change: S198G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
Blast:IG
|
251 |
312 |
1e-28 |
BLAST |
|
low complexity region
|
316 |
332 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174202
AA Change: S198G
PolyPhen 2
Score 0.301 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000134202
Gene: ENSMUSG00000022514
AA Change: S198G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
IG
|
251 |
350 |
1.46e-5 |
SMART |
|
| Meta Mutation Damage Score |
0.1606 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.9%
|
| Validation Efficiency |
98% (94/96) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009]
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal but show no biological response to IL-1. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610028H24Rik |
A |
T |
10: 76,293,346 (GRCm39) |
M156L |
probably benign |
Het |
| 4930470P17Rik |
C |
T |
2: 170,421,644 (GRCm39) |
A79T |
unknown |
Het |
| 4930522L14Rik |
A |
G |
5: 109,884,739 (GRCm39) |
I373T |
probably benign |
Het |
| Amotl1 |
G |
A |
9: 14,504,669 (GRCm39) |
Q217* |
probably null |
Het |
| Ankrd28 |
A |
T |
14: 31,454,011 (GRCm39) |
C254S |
probably damaging |
Het |
| Ap2a1 |
A |
G |
7: 44,550,970 (GRCm39) |
|
probably benign |
Het |
| Arfgef3 |
A |
T |
10: 18,529,995 (GRCm39) |
S245T |
probably benign |
Het |
| Atp1b2 |
A |
T |
11: 69,492,387 (GRCm39) |
D224E |
probably damaging |
Het |
| Bmal1 |
A |
T |
7: 112,884,244 (GRCm39) |
K94I |
probably damaging |
Het |
| Boc |
G |
A |
16: 44,308,084 (GRCm39) |
R924W |
probably damaging |
Het |
| Btbd8 |
C |
A |
5: 107,658,317 (GRCm39) |
A1117E |
probably damaging |
Het |
| Car14 |
C |
T |
3: 95,806,185 (GRCm39) |
G292D |
probably benign |
Het |
| Cenpb |
T |
C |
2: 131,020,103 (GRCm39) |
|
probably benign |
Het |
| Ces1b |
A |
T |
8: 93,789,658 (GRCm39) |
D423E |
possibly damaging |
Het |
| Cfap54 |
T |
A |
10: 92,808,556 (GRCm39) |
N1373I |
possibly damaging |
Het |
| Chrdl2 |
T |
C |
7: 99,655,748 (GRCm39) |
|
probably benign |
Het |
| Cic |
T |
G |
7: 24,982,308 (GRCm39) |
S12A |
possibly damaging |
Het |
| Csmd2 |
A |
T |
4: 128,336,685 (GRCm39) |
Q1421L |
probably benign |
Het |
| D630039A03Rik |
T |
C |
4: 57,910,452 (GRCm39) |
H120R |
possibly damaging |
Het |
| Dicer1 |
T |
A |
12: 104,658,705 (GRCm39) |
D1779V |
probably damaging |
Het |
| Dock9 |
G |
T |
14: 121,847,509 (GRCm39) |
H1016N |
possibly damaging |
Het |
| Dxo |
T |
C |
17: 35,057,974 (GRCm39) |
L352P |
probably damaging |
Het |
| Eif2b5 |
T |
A |
16: 20,318,983 (GRCm39) |
F78I |
probably damaging |
Het |
| Eri2 |
A |
G |
7: 119,384,169 (GRCm39) |
|
probably benign |
Het |
| Fbxw7 |
T |
G |
3: 84,832,996 (GRCm39) |
L13V |
possibly damaging |
Het |
| Fgf7 |
T |
A |
2: 125,877,703 (GRCm39) |
C23* |
probably null |
Het |
| Fubp1 |
T |
A |
3: 151,927,705 (GRCm39) |
|
probably null |
Het |
| Gm2663 |
A |
T |
6: 40,972,887 (GRCm39) |
I240N |
probably damaging |
Het |
| Gnb1l |
C |
T |
16: 18,366,846 (GRCm39) |
Q140* |
probably null |
Het |
| Gnptab |
G |
A |
10: 88,272,390 (GRCm39) |
R1010Q |
probably damaging |
Het |
| Gtf2h1 |
G |
A |
7: 46,472,302 (GRCm39) |
W544* |
probably null |
Het |
| Gucy2c |
C |
T |
6: 136,699,512 (GRCm39) |
E586K |
probably damaging |
Het |
| Hc |
T |
A |
2: 34,929,746 (GRCm39) |
E232V |
probably benign |
Het |
| Ifi207 |
T |
A |
1: 173,557,622 (GRCm39) |
D372V |
unknown |
Het |
| Igkv8-28 |
A |
T |
6: 70,121,102 (GRCm39) |
V15E |
probably benign |
Het |
| Lct |
A |
G |
1: 128,228,124 (GRCm39) |
I1123T |
probably damaging |
Het |
| Lhcgr |
T |
C |
17: 89,050,125 (GRCm39) |
E467G |
probably damaging |
Het |
| Macf1 |
C |
T |
4: 123,369,808 (GRCm39) |
R86K |
probably benign |
Het |
| Maml3 |
T |
A |
3: 51,763,953 (GRCm39) |
Q337L |
probably benign |
Het |
| Marchf10 |
T |
A |
11: 105,280,863 (GRCm39) |
D474V |
probably benign |
Het |
| Marchf2 |
G |
T |
17: 33,928,890 (GRCm39) |
T2K |
probably damaging |
Het |
| Mast1 |
A |
G |
8: 85,663,822 (GRCm39) |
|
probably null |
Het |
| Med12l |
T |
C |
3: 59,140,633 (GRCm39) |
I868T |
probably damaging |
Het |
| Msrb1 |
T |
C |
17: 24,959,147 (GRCm39) |
S100P |
probably damaging |
Het |
| Nlrp4c |
T |
C |
7: 6,069,125 (GRCm39) |
L342P |
probably benign |
Het |
| Nrxn3 |
T |
A |
12: 90,298,730 (GRCm39) |
V417E |
possibly damaging |
Het |
| Ntng1 |
T |
A |
3: 109,842,029 (GRCm39) |
D248V |
probably damaging |
Het |
| Oaz3 |
T |
C |
3: 94,342,305 (GRCm39) |
Q117R |
probably benign |
Het |
| Or2a56 |
A |
G |
6: 42,932,455 (GRCm39) |
I8V |
probably benign |
Het |
| Or4f58 |
A |
G |
2: 111,851,276 (GRCm39) |
Y308H |
probably benign |
Het |
| Or52e2 |
A |
G |
7: 102,804,621 (GRCm39) |
L111P |
probably benign |
Het |
| Osbpl3 |
A |
C |
6: 50,277,953 (GRCm39) |
S767A |
probably benign |
Het |
| Pafah1b1 |
A |
T |
11: 74,576,697 (GRCm39) |
|
probably benign |
Het |
| Pard6b |
A |
G |
2: 167,940,708 (GRCm39) |
T232A |
probably damaging |
Het |
| Paxip1 |
A |
T |
5: 27,970,204 (GRCm39) |
C596S |
probably damaging |
Het |
| Pnpla6 |
T |
C |
8: 3,573,818 (GRCm39) |
V422A |
probably benign |
Het |
| Psmd6 |
A |
T |
14: 14,120,932 (GRCm38) |
|
probably benign |
Het |
| Relch |
T |
A |
1: 105,647,260 (GRCm39) |
Y683* |
probably null |
Het |
| Rock2 |
T |
A |
12: 17,027,741 (GRCm39) |
C1353S |
probably damaging |
Het |
| Rpl31-ps17 |
C |
T |
12: 54,748,397 (GRCm39) |
|
noncoding transcript |
Het |
| Sel1l |
T |
A |
12: 91,780,667 (GRCm39) |
H658L |
probably damaging |
Het |
| Sh3yl1 |
T |
A |
12: 30,990,313 (GRCm39) |
L105Q |
probably damaging |
Het |
| Shroom3 |
G |
T |
5: 93,090,945 (GRCm39) |
V1151F |
probably damaging |
Het |
| Sirt1 |
T |
C |
10: 63,171,501 (GRCm39) |
K227E |
probably benign |
Het |
| Slc25a34 |
A |
T |
4: 141,350,899 (GRCm39) |
F37I |
possibly damaging |
Het |
| Slc39a5 |
T |
A |
10: 128,232,918 (GRCm39) |
I378F |
probably damaging |
Het |
| Smarcad1 |
A |
T |
6: 65,075,808 (GRCm39) |
D731V |
probably null |
Het |
| Sox6 |
T |
G |
7: 115,140,905 (GRCm39) |
K483N |
probably damaging |
Het |
| Sp140 |
T |
A |
1: 85,538,549 (GRCm39) |
D95E |
possibly damaging |
Het |
| Srgap1 |
G |
T |
10: 121,628,256 (GRCm39) |
D882E |
probably benign |
Het |
| Syne4 |
T |
C |
7: 30,016,258 (GRCm39) |
|
probably benign |
Het |
| Tasor2 |
A |
G |
13: 3,620,391 (GRCm39) |
F2170S |
probably damaging |
Het |
| Tec |
T |
C |
5: 72,926,119 (GRCm39) |
Y289C |
probably benign |
Het |
| Tmem102 |
A |
T |
11: 69,695,628 (GRCm39) |
Y115N |
probably damaging |
Het |
| Tns2 |
C |
T |
15: 102,017,369 (GRCm39) |
R281C |
probably damaging |
Het |
| Trav17 |
T |
A |
14: 54,044,097 (GRCm39) |
M1K |
probably null |
Het |
| Trdn |
T |
A |
10: 33,275,078 (GRCm39) |
|
probably null |
Het |
| Trp53 |
A |
T |
11: 69,477,747 (GRCm39) |
I8F |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,585,006 (GRCm39) |
D22064V |
probably damaging |
Het |
| Ube3c |
G |
A |
5: 29,837,836 (GRCm39) |
|
probably null |
Het |
| Ulk1 |
C |
T |
5: 110,936,813 (GRCm39) |
|
probably null |
Het |
| Upp1 |
T |
C |
11: 9,085,976 (GRCm39) |
V271A |
probably damaging |
Het |
| Vmn2r4 |
T |
C |
3: 64,296,082 (GRCm39) |
E901G |
probably damaging |
Het |
| Vmn2r96 |
G |
A |
17: 18,817,770 (GRCm39) |
G449D |
probably damaging |
Het |
| Vps37b |
T |
C |
5: 124,144,675 (GRCm39) |
K165E |
probably damaging |
Het |
| Vwf |
A |
T |
6: 125,543,268 (GRCm39) |
I185F |
possibly damaging |
Het |
| Wasf2 |
A |
G |
4: 132,912,315 (GRCm39) |
T56A |
probably benign |
Het |
| Zdhhc23 |
C |
G |
16: 43,793,952 (GRCm39) |
D241H |
possibly damaging |
Het |
| Zfp276 |
T |
C |
8: 123,981,623 (GRCm39) |
S57P |
probably benign |
Het |
| Zxdc |
A |
G |
6: 90,347,500 (GRCm39) |
H287R |
probably damaging |
Het |
|
| Other mutations in Il1rap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00402:Il1rap
|
APN |
16 |
26,541,151 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL00976:Il1rap
|
APN |
16 |
26,517,589 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01075:Il1rap
|
APN |
16 |
26,498,987 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01665:Il1rap
|
APN |
16 |
26,541,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01962:Il1rap
|
APN |
16 |
26,529,318 (GRCm39) |
nonsense |
probably null |
|
|
IGL02101:Il1rap
|
APN |
16 |
26,442,932 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL02411:Il1rap
|
APN |
16 |
26,529,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03132:Il1rap
|
APN |
16 |
26,498,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
bacchus
|
UTSW |
16 |
26,529,382 (GRCm39) |
critical splice donor site |
probably null |
|
|
I1329:Il1rap
|
UTSW |
16 |
26,511,600 (GRCm39) |
missense |
probably benign |
0.07 |
|
LCD18:Il1rap
|
UTSW |
16 |
26,450,343 (GRCm39) |
intron |
probably benign |
|
|
PIT1430001:Il1rap
|
UTSW |
16 |
26,529,343 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0302:Il1rap
|
UTSW |
16 |
26,511,544 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0454:Il1rap
|
UTSW |
16 |
26,517,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0481:Il1rap
|
UTSW |
16 |
26,511,585 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0612:Il1rap
|
UTSW |
16 |
26,519,855 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R0765:Il1rap
|
UTSW |
16 |
26,529,382 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1552:Il1rap
|
UTSW |
16 |
26,541,184 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1801:Il1rap
|
UTSW |
16 |
26,517,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1867:Il1rap
|
UTSW |
16 |
26,541,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1942:Il1rap
|
UTSW |
16 |
26,541,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1996:Il1rap
|
UTSW |
16 |
26,541,243 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2118:Il1rap
|
UTSW |
16 |
26,529,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Il1rap
|
UTSW |
16 |
26,529,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2124:Il1rap
|
UTSW |
16 |
26,529,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3104:Il1rap
|
UTSW |
16 |
26,541,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3105:Il1rap
|
UTSW |
16 |
26,541,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3106:Il1rap
|
UTSW |
16 |
26,541,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3891:Il1rap
|
UTSW |
16 |
26,495,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4133:Il1rap
|
UTSW |
16 |
26,541,636 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4409:Il1rap
|
UTSW |
16 |
26,531,015 (GRCm39) |
splice site |
probably null |
|
|
R4610:Il1rap
|
UTSW |
16 |
26,533,526 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4755:Il1rap
|
UTSW |
16 |
26,541,532 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4793:Il1rap
|
UTSW |
16 |
26,513,984 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4811:Il1rap
|
UTSW |
16 |
26,519,988 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4834:Il1rap
|
UTSW |
16 |
26,495,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5119:Il1rap
|
UTSW |
16 |
26,442,949 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5744:Il1rap
|
UTSW |
16 |
26,498,974 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6108:Il1rap
|
UTSW |
16 |
26,541,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6149:Il1rap
|
UTSW |
16 |
26,530,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Il1rap
|
UTSW |
16 |
26,529,256 (GRCm39) |
missense |
probably benign |
0.24 |
|
R6246:Il1rap
|
UTSW |
16 |
26,533,631 (GRCm39) |
missense |
probably benign |
|
|
R6249:Il1rap
|
UTSW |
16 |
26,511,598 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6254:Il1rap
|
UTSW |
16 |
26,514,020 (GRCm39) |
missense |
probably benign |
|
|
R6748:Il1rap
|
UTSW |
16 |
26,541,106 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7151:Il1rap
|
UTSW |
16 |
26,530,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7794:Il1rap
|
UTSW |
16 |
26,541,658 (GRCm39) |
missense |
probably benign |
|
|
R7818:Il1rap
|
UTSW |
16 |
26,517,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7819:Il1rap
|
UTSW |
16 |
26,541,151 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7863:Il1rap
|
UTSW |
16 |
26,495,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8240:Il1rap
|
UTSW |
16 |
26,520,001 (GRCm39) |
missense |
probably benign |
|
|
R8559:Il1rap
|
UTSW |
16 |
26,530,884 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8934:Il1rap
|
UTSW |
16 |
26,495,734 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8986:Il1rap
|
UTSW |
16 |
26,533,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9261:Il1rap
|
UTSW |
16 |
26,541,724 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9286:Il1rap
|
UTSW |
16 |
26,517,604 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9326:Il1rap
|
UTSW |
16 |
26,495,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9408:Il1rap
|
UTSW |
16 |
26,533,675 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9493:Il1rap
|
UTSW |
16 |
26,541,702 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9723:Il1rap
|
UTSW |
16 |
26,442,907 (GRCm39) |
start codon destroyed |
probably null |
0.97 |
|
X0027:Il1rap
|
UTSW |
16 |
26,519,897 (GRCm39) |
missense |
probably benign |
0.20 |
|
X0028:Il1rap
|
UTSW |
16 |
26,495,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Il1rap
|
UTSW |
16 |
26,541,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCCTCATATCTCTGAAACCAAGG -3'
(R):5'- AGCCTGAACAAACTGGGTATCC -3'
Sequencing Primer
(F):5'- CAAAGAAATATCGTCCAGAGTCTTG -3'
(R):5'- CCTGAACAAACTGGGTATCCTTGTG -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation