Incidental Mutation 'R4779:Arap1'
| ID |
368151 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap1
|
| Ensembl Gene |
ENSMUSG00000032812 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| Synonyms |
Centd2, 2410002L19Rik |
| MMRRC Submission |
045240-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4779 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
100997296-101061793 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 101053574 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Serine
at position 1301
(F1301S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102624
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000084895]
[ENSMUST00000084896]
[ENSMUST00000098243]
[ENSMUST00000107010]
|
| AlphaFold |
Q4LDD4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000084895
AA Change: F1053S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000081957
Gene: ENSMUSG00000032812
AA Change: F1053S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
37 |
N/A |
INTRINSIC |
|
PH
|
82 |
175 |
2.62e-17 |
SMART |
|
PH
|
195 |
285 |
3.6e-6 |
SMART |
|
ArfGap
|
289 |
415 |
2.4e-22 |
SMART |
|
PH
|
498 |
606 |
1.23e-13 |
SMART |
|
PH
|
616 |
710 |
1.08e0 |
SMART |
|
RhoGAP
|
722 |
904 |
1.35e-63 |
SMART |
|
Pfam:RA
|
926 |
1015 |
1.5e-10 |
PFAM |
|
PH
|
1029 |
1141 |
8.58e-13 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000084896
AA Change: F1301S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000081958
Gene: ENSMUSG00000032812
AA Change: F1301S
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
1.72e-7 |
SMART |
|
low complexity region
|
92 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
135 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
167 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
227 |
N/A |
INTRINSIC |
|
low complexity region
|
267 |
285 |
N/A |
INTRINSIC |
|
PH
|
330 |
423 |
2.62e-17 |
SMART |
|
PH
|
443 |
533 |
3.6e-6 |
SMART |
|
ArfGap
|
537 |
663 |
2.4e-22 |
SMART |
|
PH
|
746 |
854 |
1.23e-13 |
SMART |
|
PH
|
864 |
958 |
1.08e0 |
SMART |
|
RhoGAP
|
970 |
1152 |
1.35e-63 |
SMART |
|
Pfam:RA
|
1174 |
1263 |
6.6e-13 |
PFAM |
|
PH
|
1277 |
1400 |
8e-13 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000098243
AA Change: F587S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000095844
Gene: ENSMUSG00000032812
AA Change: F587S
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
32 |
140 |
1.23e-13 |
SMART |
|
PH
|
150 |
244 |
1.08e0 |
SMART |
|
RhoGAP
|
256 |
438 |
1.35e-63 |
SMART |
|
Pfam:RA
|
460 |
549 |
1.2e-11 |
PFAM |
|
PH
|
563 |
675 |
8.58e-13 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107010
AA Change: F1301S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000102624
Gene: ENSMUSG00000032812
AA Change: F1301S
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
1.72e-7 |
SMART |
|
low complexity region
|
92 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
135 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
167 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
227 |
N/A |
INTRINSIC |
|
low complexity region
|
267 |
285 |
N/A |
INTRINSIC |
|
PH
|
330 |
423 |
2.62e-17 |
SMART |
|
PH
|
443 |
533 |
3.6e-6 |
SMART |
|
ArfGap
|
537 |
663 |
2.4e-22 |
SMART |
|
PH
|
746 |
854 |
1.23e-13 |
SMART |
|
PH
|
864 |
958 |
1.08e0 |
SMART |
|
RhoGAP
|
970 |
1152 |
1.35e-63 |
SMART |
|
Pfam:RA
|
1174 |
1263 |
1.9e-10 |
PFAM |
|
PH
|
1277 |
1389 |
8.58e-13 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124637
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125284
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156017
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000210162
|
| Meta Mutation Damage Score |
0.9308 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.8%
|
| Validation Efficiency |
98% (95/97) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930562C15Rik |
T |
A |
16: 4,667,613 (GRCm39) |
S335T |
unknown |
Het |
| 4933421I07Rik |
T |
A |
7: 42,097,455 (GRCm39) |
H13L |
possibly damaging |
Het |
| 6030468B19Rik |
A |
G |
11: 117,696,834 (GRCm39) |
T185A |
probably benign |
Het |
| Abcc1 |
T |
A |
16: 14,228,635 (GRCm39) |
V294E |
probably benign |
Het |
| Abhd16b |
A |
G |
2: 181,135,253 (GRCm39) |
T52A |
possibly damaging |
Het |
| Actl7a |
A |
T |
4: 56,743,632 (GRCm39) |
N53I |
probably benign |
Het |
| Ankmy1 |
T |
C |
1: 92,814,445 (GRCm39) |
E354G |
probably benign |
Het |
| Arfgef1 |
A |
T |
1: 10,223,958 (GRCm39) |
W1447R |
probably damaging |
Het |
| Atoh7 |
ATGGCGCT |
AT |
10: 62,936,187 (GRCm39) |
|
probably benign |
Het |
| Ccl24 |
T |
A |
5: 135,601,811 (GRCm39) |
T6S |
possibly damaging |
Het |
| Cep152 |
G |
T |
2: 125,410,812 (GRCm39) |
P1292Q |
possibly damaging |
Het |
| Cfap46 |
T |
C |
7: 139,239,731 (GRCm39) |
|
probably benign |
Het |
| Chd6 |
A |
T |
2: 160,791,477 (GRCm39) |
S2627T |
probably damaging |
Het |
| Chd8 |
A |
T |
14: 52,468,963 (GRCm39) |
S552T |
probably damaging |
Het |
| Ciita |
C |
A |
16: 10,329,230 (GRCm39) |
L502M |
probably damaging |
Het |
| Clic1 |
T |
C |
17: 35,271,463 (GRCm39) |
F31S |
probably damaging |
Het |
| Cntnap1 |
T |
A |
11: 101,068,898 (GRCm39) |
I147N |
possibly damaging |
Het |
| Cplane1 |
T |
C |
15: 8,248,322 (GRCm39) |
S1624P |
probably benign |
Het |
| Crispld1 |
T |
A |
1: 17,819,831 (GRCm39) |
D276E |
probably benign |
Het |
| Cspg4 |
A |
T |
9: 56,793,092 (GRCm39) |
N276Y |
probably damaging |
Het |
| Cspg4b |
A |
T |
13: 113,504,870 (GRCm39) |
N2000Y |
possibly damaging |
Het |
| Cwf19l2 |
A |
G |
9: 3,410,035 (GRCm39) |
M55V |
possibly damaging |
Het |
| Cyp2c69 |
T |
C |
19: 39,866,038 (GRCm39) |
N185S |
probably benign |
Het |
| Dop1b |
T |
C |
16: 93,553,969 (GRCm39) |
I301T |
probably damaging |
Het |
| Epg5 |
T |
C |
18: 78,034,580 (GRCm39) |
V1443A |
probably benign |
Het |
| Ephb4 |
T |
C |
5: 137,363,964 (GRCm39) |
V612A |
probably benign |
Het |
| Fcgbp |
T |
A |
7: 27,794,362 (GRCm39) |
C1189S |
probably damaging |
Het |
| Fgfr2 |
T |
G |
7: 129,786,923 (GRCm39) |
|
probably benign |
Het |
| Fmn2 |
A |
G |
1: 174,437,461 (GRCm39) |
E1144G |
probably damaging |
Het |
| Fmo3 |
T |
C |
1: 162,796,407 (GRCm39) |
Y55C |
probably damaging |
Het |
| Frmpd1 |
A |
G |
4: 45,229,865 (GRCm39) |
T11A |
probably damaging |
Het |
| Ghdc |
G |
T |
11: 100,660,929 (GRCm39) |
Q79K |
possibly damaging |
Het |
| Gm11677 |
C |
T |
11: 111,615,537 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5591 |
T |
C |
7: 38,221,680 (GRCm39) |
T130A |
probably damaging |
Het |
| Heg1 |
T |
G |
16: 33,540,142 (GRCm39) |
D367E |
probably benign |
Het |
| Igkv13-84 |
C |
T |
6: 68,916,894 (GRCm39) |
P64S |
probably damaging |
Het |
| Il10rb |
T |
A |
16: 91,211,545 (GRCm39) |
S128T |
possibly damaging |
Het |
| Il15ra |
T |
A |
2: 11,723,117 (GRCm39) |
I47N |
probably damaging |
Het |
| Il33 |
C |
A |
19: 29,936,311 (GRCm39) |
S207* |
probably null |
Het |
| Itgb7 |
A |
G |
15: 102,132,848 (GRCm39) |
Y155H |
possibly damaging |
Het |
| Kdm5a |
A |
G |
6: 120,346,060 (GRCm39) |
|
probably benign |
Het |
| Kif11 |
G |
A |
19: 37,406,397 (GRCm39) |
V987I |
probably benign |
Het |
| Krtap19-2 |
G |
A |
16: 88,670,762 (GRCm39) |
|
probably benign |
Het |
| Krtap24-1 |
T |
A |
16: 88,408,417 (GRCm39) |
R236S |
probably damaging |
Het |
| L3mbtl2 |
A |
G |
15: 81,566,813 (GRCm39) |
I406V |
probably benign |
Het |
| Lrp2 |
A |
T |
2: 69,290,059 (GRCm39) |
H3593Q |
possibly damaging |
Het |
| Mavs |
G |
T |
2: 131,082,285 (GRCm39) |
W56C |
probably damaging |
Het |
| Mn1 |
C |
T |
5: 111,567,526 (GRCm39) |
P499S |
probably damaging |
Het |
| Ntn5 |
T |
A |
7: 45,340,895 (GRCm39) |
C178S |
probably damaging |
Het |
| Nufip2 |
A |
G |
11: 77,577,154 (GRCm39) |
H34R |
unknown |
Het |
| Or5p51 |
T |
A |
7: 107,444,755 (GRCm39) |
M62L |
possibly damaging |
Het |
| Or6f2 |
T |
A |
7: 139,756,363 (GRCm39) |
L110Q |
probably damaging |
Het |
| Osbpl10 |
C |
T |
9: 114,938,598 (GRCm39) |
S86L |
probably damaging |
Het |
| Pitpna |
T |
A |
11: 75,511,153 (GRCm39) |
M242K |
possibly damaging |
Het |
| Pnpla6 |
T |
C |
8: 3,572,838 (GRCm39) |
V345A |
probably benign |
Het |
| Polk |
A |
G |
13: 96,632,999 (GRCm39) |
|
probably null |
Het |
| Polr3k |
A |
G |
2: 181,506,340 (GRCm39) |
Y30C |
probably damaging |
Het |
| Pramel6 |
A |
G |
2: 87,339,941 (GRCm39) |
H235R |
probably benign |
Het |
| Ptpra |
G |
A |
2: 130,379,537 (GRCm39) |
V364I |
probably damaging |
Het |
| Recql |
A |
G |
6: 142,309,426 (GRCm39) |
|
probably benign |
Het |
| Ring1 |
T |
C |
17: 34,241,263 (GRCm39) |
|
probably benign |
Het |
| Rufy4 |
T |
C |
1: 74,186,822 (GRCm39) |
C537R |
probably damaging |
Het |
| Samsn1 |
C |
A |
16: 75,744,177 (GRCm39) |
|
noncoding transcript |
Het |
| Scara5 |
A |
G |
14: 65,968,198 (GRCm39) |
H157R |
probably benign |
Het |
| Sdc3 |
C |
T |
4: 130,546,376 (GRCm39) |
P245L |
probably damaging |
Het |
| Slc18b1 |
T |
A |
10: 23,696,767 (GRCm39) |
M318K |
possibly damaging |
Het |
| Slc26a10 |
C |
T |
10: 127,009,224 (GRCm39) |
A638T |
possibly damaging |
Het |
| Slc35f2 |
T |
A |
9: 53,717,013 (GRCm39) |
W259R |
possibly damaging |
Het |
| Spata13 |
G |
A |
14: 60,991,356 (GRCm39) |
W366* |
probably null |
Het |
| Sptlc3 |
A |
G |
2: 139,431,509 (GRCm39) |
T344A |
probably benign |
Het |
| Tap1 |
T |
C |
17: 34,412,865 (GRCm39) |
V560A |
probably damaging |
Het |
| Tbc1d1 |
T |
C |
5: 64,435,389 (GRCm39) |
|
probably null |
Het |
| Tlr11 |
A |
G |
14: 50,598,707 (GRCm39) |
Y231C |
possibly damaging |
Het |
| Tmem245 |
A |
T |
4: 56,936,468 (GRCm39) |
S230T |
possibly damaging |
Het |
| Tnnt3 |
C |
T |
7: 142,068,020 (GRCm39) |
|
probably benign |
Het |
| Traf7 |
C |
G |
17: 24,729,412 (GRCm39) |
|
probably benign |
Het |
| Tshz2 |
A |
G |
2: 169,804,601 (GRCm39) |
|
probably benign |
Het |
| Tshz3 |
T |
C |
7: 36,468,397 (GRCm39) |
S129P |
probably damaging |
Het |
| Ttc6 |
A |
T |
12: 57,776,237 (GRCm39) |
N1727I |
probably damaging |
Het |
| Ttc7b |
A |
G |
12: 100,369,621 (GRCm39) |
S383P |
probably damaging |
Het |
| Tulp3 |
T |
A |
6: 128,300,083 (GRCm39) |
I448F |
probably damaging |
Het |
| Ube3b |
T |
C |
5: 114,542,778 (GRCm39) |
|
probably null |
Het |
| Vav1 |
G |
A |
17: 57,603,552 (GRCm39) |
V84I |
probably damaging |
Het |
| Vav3 |
A |
T |
3: 109,416,110 (GRCm39) |
K243I |
possibly damaging |
Het |
| Vmn1r25 |
T |
A |
6: 57,956,011 (GRCm39) |
I93F |
probably damaging |
Het |
| Vmn2r73 |
C |
T |
7: 85,520,923 (GRCm39) |
W348* |
probably null |
Het |
| Zdbf2 |
A |
G |
1: 63,342,397 (GRCm39) |
R259G |
possibly damaging |
Het |
|
| Other mutations in Arap1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00517:Arap1
|
APN |
7 |
101,037,256 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01311:Arap1
|
APN |
7 |
101,037,343 (GRCm39) |
nonsense |
probably null |
|
|
IGL01349:Arap1
|
APN |
7 |
101,036,359 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL01521:Arap1
|
APN |
7 |
101,049,812 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01869:Arap1
|
APN |
7 |
101,049,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02156:Arap1
|
APN |
7 |
101,037,937 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02320:Arap1
|
APN |
7 |
101,034,236 (GRCm39) |
missense |
probably benign |
|
|
IGL02478:Arap1
|
APN |
7 |
101,049,332 (GRCm39) |
splice site |
probably null |
|
|
R0133:Arap1
|
UTSW |
7 |
101,035,436 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0233:Arap1
|
UTSW |
7 |
101,049,448 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R0233:Arap1
|
UTSW |
7 |
101,049,448 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R0412:Arap1
|
UTSW |
7 |
101,039,429 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0616:Arap1
|
UTSW |
7 |
101,050,857 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0838:Arap1
|
UTSW |
7 |
101,049,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0962:Arap1
|
UTSW |
7 |
101,034,121 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1186:Arap1
|
UTSW |
7 |
101,053,476 (GRCm39) |
splice site |
probably benign |
|
|
R1405:Arap1
|
UTSW |
7 |
101,047,643 (GRCm39) |
splice site |
probably null |
|
|
R1405:Arap1
|
UTSW |
7 |
101,047,643 (GRCm39) |
splice site |
probably null |
|
|
R1724:Arap1
|
UTSW |
7 |
101,049,733 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1793:Arap1
|
UTSW |
7 |
101,037,829 (GRCm39) |
missense |
probably benign |
|
|
R1959:Arap1
|
UTSW |
7 |
101,022,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1960:Arap1
|
UTSW |
7 |
101,022,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Arap1
|
UTSW |
7 |
101,050,725 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2128:Arap1
|
UTSW |
7 |
101,058,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3737:Arap1
|
UTSW |
7 |
101,049,484 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3851:Arap1
|
UTSW |
7 |
101,039,372 (GRCm39) |
nonsense |
probably null |
|
|
R4034:Arap1
|
UTSW |
7 |
101,049,484 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4386:Arap1
|
UTSW |
7 |
101,034,778 (GRCm39) |
missense |
probably benign |
|
|
R4435:Arap1
|
UTSW |
7 |
101,039,461 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4786:Arap1
|
UTSW |
7 |
101,034,212 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4850:Arap1
|
UTSW |
7 |
101,047,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Arap1
|
UTSW |
7 |
101,051,009 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5253:Arap1
|
UTSW |
7 |
101,037,851 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5342:Arap1
|
UTSW |
7 |
101,054,167 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5367:Arap1
|
UTSW |
7 |
101,058,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5397:Arap1
|
UTSW |
7 |
101,034,119 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5968:Arap1
|
UTSW |
7 |
101,043,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6052:Arap1
|
UTSW |
7 |
101,053,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6574:Arap1
|
UTSW |
7 |
101,053,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6645:Arap1
|
UTSW |
7 |
101,057,318 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R7060:Arap1
|
UTSW |
7 |
101,058,564 (GRCm39) |
splice site |
probably null |
|
|
R7191:Arap1
|
UTSW |
7 |
101,034,199 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7323:Arap1
|
UTSW |
7 |
101,049,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7349:Arap1
|
UTSW |
7 |
101,039,435 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7516:Arap1
|
UTSW |
7 |
101,058,538 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7922:Arap1
|
UTSW |
7 |
101,053,621 (GRCm39) |
nonsense |
probably null |
|
|
R8034:Arap1
|
UTSW |
7 |
101,043,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8293:Arap1
|
UTSW |
7 |
101,050,141 (GRCm39) |
missense |
probably benign |
|
|
R8493:Arap1
|
UTSW |
7 |
101,035,725 (GRCm39) |
nonsense |
probably null |
|
|
R8810:Arap1
|
UTSW |
7 |
101,053,585 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8811:Arap1
|
UTSW |
7 |
101,036,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8928:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8930:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8931:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8941:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9014:Arap1
|
UTSW |
7 |
101,053,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9144:Arap1
|
UTSW |
7 |
101,047,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9164:Arap1
|
UTSW |
7 |
101,041,090 (GRCm39) |
nonsense |
probably null |
|
|
R9215:Arap1
|
UTSW |
7 |
101,049,214 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9340:Arap1
|
UTSW |
7 |
101,037,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9519:Arap1
|
UTSW |
7 |
101,043,946 (GRCm39) |
start gained |
probably benign |
|
|
R9790:Arap1
|
UTSW |
7 |
101,037,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9791:Arap1
|
UTSW |
7 |
101,037,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCATCTACAAGCAGGGTGG -3'
(R):5'- TCATCAGTCATGGTGCTGCC -3'
Sequencing Primer
(F):5'- TGGGAGCTGGTGGCAAC -3'
(R):5'- AGTCATGGTGCTGCCGAGAC -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation