Mutagenetix > Incidental Mutation

Incidental Mutation 'R4112:Vmn2r129'

368261

Institutional Source

Beutler Lab

Gene Symbol

Vmn2r129

Ensembl Gene

ENSMUSG00000057021

Gene Name

vomeronasal 2, receptor 129

Synonyms

Vmn2r-ps160, Vmn2r-ps159, V2r9, V2r8

MMRRC Submission

040989-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.701) question?

Stock #

R4112 (G1)

Quality Score

Status

Validated

Chromosome

Chromosomal Location

156683398-156691794 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

G to T at 156686692 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

A0A3Q4EIC8

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000074107

SMART Domains

Protein: ENSMUSP00000128975
Gene: ENSMUSG00000057021

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Pfam:ANF_receptor	76	423	1.4e-32	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000096792

SMART Domains

Protein: ENSMUSP00000094554
Gene: ENSMUSG00000057021

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Pfam:ANF_receptor	76	441	3.7e-31	PFAM
Pfam:NCD3G	510	563	1.4e-20	PFAM
Pfam:7tm_3	596	831	1.9e-56	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000189559

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.2%
3x: 98.7%
10x: 97.6%
20x: 96.3%

Validation Efficiency

97% (56/58)

Allele List at MGI

Other mutations in this stock

Total: 52 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700012B07Rik	G	T	11: 109,684,980 (GRCm39)	C172*	probably null	Het
Aamp	A	G	1: 74,320,386 (GRCm39)		probably benign	Het
Abcb4	A	G	5: 8,986,783 (GRCm39)		probably null	Het
Adam6b	T	A	12: 113,453,256 (GRCm39)	F24L	possibly damaging	Het
Alms1	G	A	6: 85,597,870 (GRCm39)	V1368I	probably benign	Het
Angpt2	T	A	8: 18,749,139 (GRCm39)	Q326L	probably damaging	Het
Armc9	T	A	1: 86,116,661 (GRCm39)	I327N	possibly damaging	Het
Bace2	A	G	16: 97,237,856 (GRCm39)	T436A	probably benign	Het
Ccdc162	T	A	10: 41,532,324 (GRCm39)	E450V	possibly damaging	Het
Ccdc7b	G	T	8: 129,811,708 (GRCm39)		probably benign	Het
Cdh17	T	C	4: 11,814,628 (GRCm39)	S728P	probably damaging	Het
Chia1	T	C	3: 106,035,844 (GRCm39)	L168P	probably damaging	Het
Cnot1	A	C	8: 96,500,246 (GRCm39)	L111V	probably damaging	Het
Col14a1	A	T	15: 55,226,955 (GRCm39)	N235I	unknown	Het
Col2a1	A	C	15: 97,881,582 (GRCm39)	L787R	probably benign	Het
Cyp3a25	A	T	5: 145,939,841 (GRCm39)	D55E	probably benign	Het
Dennd6a	A	T	14: 26,349,673 (GRCm39)		probably benign	Het
Dnajc28	G	A	16: 91,413,755 (GRCm39)	T187M	probably damaging	Het
Etfbkmt	T	C	6: 149,046,089 (GRCm39)		probably benign	Het
Etfrf1	T	C	6: 145,161,098 (GRCm39)	Y23H	probably damaging	Het
Gemin4	T	A	11: 76,103,645 (GRCm39)	E372V	probably damaging	Het
Glyr1	T	C	16: 4,836,350 (GRCm39)	K500E	possibly damaging	Het
Gm10271	A	T	10: 116,803,943 (GRCm39)		probably benign	Het
Gm20775	A	T	Y: 10,641,878 (GRCm39)		noncoding transcript	Het
Gm5578	A	G	6: 112,583,466 (GRCm39)		noncoding transcript	Het
Gxylt2	A	G	6: 100,760,167 (GRCm39)	N234S	probably damaging	Het
Kcna6	G	C	6: 126,716,737 (GRCm39)	R51G	probably damaging	Het
Klf17	A	G	4: 117,617,898 (GRCm39)	V153A	possibly damaging	Het
L3mbtl2	T	C	15: 81,566,170 (GRCm39)	V331A	possibly damaging	Het
Med1	A	T	11: 98,070,913 (GRCm39)	V110E	probably damaging	Het
Nsmaf	A	C	4: 6,417,188 (GRCm39)	Y535*	probably null	Het
Pcdh10	G	A	3: 45,336,055 (GRCm39)	V790M	probably damaging	Het
Phlpp1	A	G	1: 106,292,068 (GRCm39)	T976A	probably damaging	Het
Prelid3a	T	C	18: 67,605,967 (GRCm39)	Y25H	probably damaging	Het
Ptprk	T	A	10: 28,351,284 (GRCm39)		probably null	Het
Rbm5	A	T	9: 107,642,796 (GRCm39)	D79E	probably damaging	Het
Rhox3f	G	T	X: 36,763,672 (GRCm39)	E140*	probably null	Het
Rnd3	T	A	2: 51,038,242 (GRCm39)	T78S	possibly damaging	Het
Scart2	G	T	7: 139,878,281 (GRCm39)	G1003*	probably null	Het
Sgca	T	C	11: 94,863,396 (GRCm39)	T27A	possibly damaging	Het
Slc10a2	C	T	8: 5,155,135 (GRCm39)	D17N	probably benign	Het
Snap23	C	T	2: 120,414,856 (GRCm39)		probably benign	Het
Sptb	T	A	12: 76,644,553 (GRCm39)	T2098S	probably damaging	Het
Src	T	A	2: 157,304,946 (GRCm39)	L165H	probably damaging	Het
Srr	G	T	11: 74,803,898 (GRCm39)	Q20K	probably benign	Het
Stt3b	A	T	9: 115,095,206 (GRCm39)	F275Y	probably damaging	Het
Sucnr1	C	G	3: 59,994,215 (GRCm39)	R248G	probably damaging	Het
Thsd7b	A	T	1: 130,044,356 (GRCm39)	D1112V	probably benign	Het
Tmem80	A	G	7: 140,913,692 (GRCm39)		probably benign	Het
Top2a	C	A	11: 98,913,786 (GRCm39)	K18N	probably damaging	Het
Ttc24	T	A	3: 87,981,946 (GRCm39)	D40V	probably damaging	Het
Zfp3	T	A	11: 70,662,333 (GRCm39)	S97R	probably benign	Het

Other mutations in Vmn2r129

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL00977:Vmn2r129	APN	4	156,686,491 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,686,692 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,686,558 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,690,755 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,690,730 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,690,441 (GRCm39)	splice site	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,690,779 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,686,857 (GRCm39)	exon	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,687,885 (GRCm39)	intron	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,686,558 (GRCm39)	exon	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,690,730 (GRCm39)	exon	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,690,441 (GRCm39)	splice site	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,686,900 (GRCm39)	exon	noncoding transcript
IGL01829:Vmn2r129	APN	4	156,685,614 (GRCm39)	intron	noncoding transcript
IGL01863:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01864:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01865:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01866:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01868:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01869:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01872:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01873:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01876:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01877:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01878:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01879:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01880:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01884:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01885:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01886:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01887:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01888:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01890:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01891:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01893:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01894:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01896:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01897:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01898:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01899:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01901:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01902:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01903:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01904:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01905:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01906:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01907:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01908:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01909:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01913:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01915:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01916:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01917:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01918:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01919:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01920:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01921:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01922:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01923:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01927:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01928:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01929:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01930:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01931:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01932:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01935:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01937:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01939:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01941:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01942:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01944:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01945:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01946:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01949:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01953:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01954:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01956:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01957:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL02270:Vmn2r129	APN	4	156,686,950 (GRCm39)	exon	noncoding transcript
R1746:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R1870:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R2147:Vmn2r129	UTSW	4	156,687,014 (GRCm39)	critical splice donor site	noncoding transcript
R2168:Vmn2r129	UTSW	4	156,690,673 (GRCm39)	exon	noncoding transcript
R2345:Vmn2r129	UTSW	4	156,689,334 (GRCm39)	splice site	noncoding transcript
R2510:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R2899:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3106:Vmn2r129	UTSW	4	156,685,730 (GRCm39)	intron	noncoding transcript
R3122:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3405:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3430:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3732:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3751:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R4108:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R4120:Vmn2r129	UTSW	4	156,686,778 (GRCm39)	exon	noncoding transcript
R4135:Vmn2r129	UTSW	4	156,691,085 (GRCm39)	exon	noncoding transcript
R4302:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R4475:Vmn2r129	UTSW	4	156,691,085 (GRCm39)	exon	noncoding transcript
R4840:Vmn2r129	UTSW	4	156,685,733 (GRCm39)	intron	noncoding transcript
R4872:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R5144:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R5271:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R5625:Vmn2r129	UTSW	4	156,686,505 (GRCm39)	exon	noncoding transcript
R5775:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- ATGCAGATATACATGACAAGGGCTAC -3'
(R):5'- GCAGTGATGTCCATTCCAAGG -3'

Sequencing Primer
(F):5'- ATGACATCTTCAGCAAAGGTTG -3'
(R):5'- CAGTGATGTCCATTCCAAGGTGTTG -3'

Posted On

2016-01-15