Incidental Mutation 'R4799:Cul9'
| ID |
369392 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cul9
|
| Ensembl Gene |
ENSMUSG00000040327 |
| Gene Name |
cullin 9 |
| Synonyms |
Parc, 1810035I07Rik |
| MMRRC Submission |
041997-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.227)
|
| Stock # |
R4799 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
46811535-46857314 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46811770 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 2486
(D2486G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138418
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046497]
[ENSMUST00000066026]
[ENSMUST00000182485]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000046497
|
| SMART Domains |
Protein: ENSMUSP00000045283
Gene: ENSMUSG00000040658
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nuc_deoxyrib_tr
|
12 |
144 |
3.8e-21 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000066026
AA Change: D2476G
PolyPhen 2
Score 0.481 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000067736
Gene: ENSMUSG00000040327
AA Change: D2476G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
46 |
61 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
131 |
N/A |
INTRINSIC |
|
low complexity region
|
345 |
357 |
N/A |
INTRINSIC |
|
Pfam:Cul7
|
367 |
441 |
1e-35 |
PFAM |
|
low complexity region
|
447 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
525 |
540 |
N/A |
INTRINSIC |
|
low complexity region
|
845 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
873 |
880 |
N/A |
INTRINSIC |
|
APC10
|
1166 |
1325 |
1.97e-56 |
SMART |
|
low complexity region
|
1437 |
1450 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1578 |
N/A |
INTRINSIC |
|
low complexity region
|
1646 |
1671 |
N/A |
INTRINSIC |
|
Cullin_Nedd8
|
1867 |
1950 |
7.55e-6 |
SMART |
|
Blast:RING
|
2074 |
2122 |
2e-13 |
BLAST |
|
IBR
|
2144 |
2207 |
8.99e-14 |
SMART |
|
IBR
|
2228 |
2283 |
4.66e-2 |
SMART |
|
low complexity region
|
2503 |
2520 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000181301
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182315
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000182485
AA Change: D2486G
PolyPhen 2
Score 0.787 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000138418
Gene: ENSMUSG00000040327
AA Change: D2486G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
46 |
61 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
131 |
N/A |
INTRINSIC |
|
low complexity region
|
345 |
357 |
N/A |
INTRINSIC |
|
Pfam:Cul7
|
367 |
442 |
1.4e-33 |
PFAM |
|
low complexity region
|
447 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
525 |
540 |
N/A |
INTRINSIC |
|
low complexity region
|
845 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
873 |
880 |
N/A |
INTRINSIC |
|
APC10
|
1166 |
1325 |
1.97e-56 |
SMART |
|
low complexity region
|
1437 |
1450 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1578 |
N/A |
INTRINSIC |
|
low complexity region
|
1646 |
1671 |
N/A |
INTRINSIC |
|
Cullin_Nedd8
|
1867 |
1950 |
7.55e-6 |
SMART |
|
Blast:RING
|
2074 |
2122 |
3e-13 |
BLAST |
|
IBR
|
2144 |
2207 |
8.99e-14 |
SMART |
|
IBR
|
2228 |
2283 |
4.66e-2 |
SMART |
|
coiled coil region
|
2461 |
2497 |
N/A |
INTRINSIC |
|
low complexity region
|
2513 |
2530 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182530
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183078
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183312
|
| Meta Mutation Damage Score |
0.0742 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 92.6%
|
| Validation Efficiency |
97% (122/126) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body weight, increased incidence of tumors, and decreased cellular sensitivity to radiation-induced apoptosis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 119 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abhd12b |
C |
G |
12: 70,215,838 (GRCm39) |
S170C |
probably damaging |
Het |
| Acads |
T |
A |
5: 115,251,149 (GRCm39) |
T112S |
probably benign |
Het |
| Adgrl1 |
A |
G |
8: 84,662,202 (GRCm39) |
H1021R |
probably benign |
Het |
| Ago3 |
A |
T |
4: 126,241,665 (GRCm39) |
|
probably null |
Het |
| Ap5m1 |
A |
G |
14: 49,318,527 (GRCm39) |
K412E |
probably benign |
Het |
| Arid1b |
C |
T |
17: 5,389,496 (GRCm39) |
P1681S |
probably damaging |
Het |
| Atxn10 |
T |
C |
15: 85,260,909 (GRCm39) |
|
probably null |
Het |
| AU040320 |
A |
G |
4: 126,733,462 (GRCm39) |
T661A |
probably benign |
Het |
| Bhmt1b |
C |
A |
18: 87,774,573 (GRCm39) |
A32E |
probably damaging |
Het |
| Capn7 |
T |
C |
14: 31,082,514 (GRCm39) |
I455M |
probably benign |
Het |
| Capzb |
A |
G |
4: 138,920,310 (GRCm39) |
|
probably benign |
Het |
| Car10 |
G |
A |
11: 93,469,492 (GRCm39) |
V156I |
possibly damaging |
Het |
| Cbs |
T |
A |
17: 31,851,826 (GRCm39) |
D59V |
probably damaging |
Het |
| Ccar2 |
T |
C |
14: 70,377,003 (GRCm39) |
E819G |
probably damaging |
Het |
| Cdc73 |
T |
A |
1: 143,503,613 (GRCm39) |
Q346L |
probably benign |
Het |
| Cdhr4 |
T |
C |
9: 107,875,898 (GRCm39) |
|
probably benign |
Het |
| Cfap251 |
C |
T |
5: 123,440,835 (GRCm39) |
H1131Y |
probably benign |
Het |
| Chd2 |
A |
T |
7: 73,134,184 (GRCm39) |
M721K |
possibly damaging |
Het |
| Cntnap5b |
G |
A |
1: 100,286,450 (GRCm39) |
G402R |
probably benign |
Het |
| Cps1 |
T |
C |
1: 67,182,145 (GRCm39) |
Y120H |
probably damaging |
Het |
| Csf2 |
T |
C |
11: 54,140,306 (GRCm39) |
D44G |
probably benign |
Het |
| Cubn |
T |
A |
2: 13,291,835 (GRCm39) |
Q3330L |
possibly damaging |
Het |
| Cubn |
A |
G |
2: 13,355,869 (GRCm39) |
S1788P |
probably damaging |
Het |
| Cyp2c40 |
A |
T |
19: 39,762,293 (GRCm39) |
S451R |
probably damaging |
Het |
| Cyp51 |
T |
A |
5: 4,133,256 (GRCm39) |
T461S |
probably damaging |
Het |
| Cyth1 |
T |
C |
11: 118,074,768 (GRCm39) |
M164V |
probably damaging |
Het |
| D130043K22Rik |
T |
C |
13: 25,062,023 (GRCm39) |
I664T |
probably damaging |
Het |
| Ddc |
T |
C |
11: 11,796,632 (GRCm39) |
|
probably null |
Het |
| Ddx21 |
A |
T |
10: 62,423,900 (GRCm39) |
D589E |
probably damaging |
Het |
| Dgkb |
C |
T |
12: 38,164,567 (GRCm39) |
R113C |
possibly damaging |
Het |
| Dglucy |
A |
T |
12: 100,816,602 (GRCm39) |
M415L |
probably benign |
Het |
| Efnb2 |
A |
T |
8: 8,673,104 (GRCm39) |
|
probably null |
Het |
| Elp4 |
T |
A |
2: 105,639,612 (GRCm39) |
Q189L |
probably damaging |
Het |
| Enpp2 |
T |
C |
15: 54,773,490 (GRCm39) |
N77S |
probably damaging |
Het |
| Eps15 |
G |
A |
4: 109,223,727 (GRCm39) |
|
probably benign |
Het |
| F2rl1 |
G |
A |
13: 95,650,477 (GRCm39) |
S135F |
possibly damaging |
Het |
| Fam133b |
T |
C |
5: 3,607,815 (GRCm39) |
M65T |
probably damaging |
Het |
| Fanca |
A |
G |
8: 124,014,941 (GRCm39) |
V689A |
probably damaging |
Het |
| Fbh1 |
C |
T |
2: 11,760,558 (GRCm39) |
C79Y |
probably damaging |
Het |
| Fbxw7 |
C |
T |
3: 84,811,168 (GRCm39) |
Q98* |
probably null |
Het |
| Flrt3 |
T |
C |
2: 140,502,086 (GRCm39) |
N514S |
probably damaging |
Het |
| Foxj3 |
A |
T |
4: 119,478,857 (GRCm39) |
S438C |
unknown |
Het |
| Gcm2 |
T |
C |
13: 41,256,970 (GRCm39) |
K260E |
possibly damaging |
Het |
| Gm12863 |
C |
T |
4: 118,811,685 (GRCm39) |
|
noncoding transcript |
Het |
| Gpnmb |
G |
T |
6: 49,022,417 (GRCm39) |
|
probably null |
Het |
| Gsap |
C |
A |
5: 21,455,941 (GRCm39) |
N379K |
probably benign |
Het |
| Hsd3b1 |
T |
A |
3: 98,760,181 (GRCm39) |
Y270F |
probably benign |
Het |
| Ift70a2 |
T |
A |
2: 75,807,729 (GRCm39) |
Y261F |
probably benign |
Het |
| Il22 |
C |
A |
10: 118,041,058 (GRCm39) |
R55S |
probably damaging |
Het |
| Kcnd3 |
C |
T |
3: 105,566,082 (GRCm39) |
A421V |
probably damaging |
Het |
| Klhdc3 |
T |
C |
17: 46,988,226 (GRCm39) |
R180G |
possibly damaging |
Het |
| Lmbrd1 |
G |
A |
1: 24,784,056 (GRCm39) |
|
probably null |
Het |
| Lrrcc1 |
C |
T |
3: 14,601,156 (GRCm39) |
R63* |
probably null |
Het |
| Lyar |
A |
G |
5: 38,382,123 (GRCm39) |
D35G |
probably damaging |
Het |
| Mbd4 |
C |
T |
6: 115,822,283 (GRCm39) |
R442Q |
probably benign |
Het |
| Mib2 |
G |
T |
4: 155,744,229 (GRCm39) |
S144R |
probably benign |
Het |
| Mms22l |
A |
T |
4: 24,580,052 (GRCm39) |
|
probably null |
Het |
| Mtmr3 |
G |
A |
11: 4,437,764 (GRCm39) |
H897Y |
probably benign |
Het |
| Muc5b |
T |
A |
7: 141,401,453 (GRCm39) |
C566* |
probably null |
Het |
| Nap1l4 |
A |
T |
7: 143,088,200 (GRCm39) |
|
probably null |
Het |
| Ncor2 |
A |
T |
5: 125,114,124 (GRCm39) |
|
probably null |
Het |
| Ndufa7 |
T |
C |
17: 34,057,187 (GRCm39) |
|
probably benign |
Het |
| Ndufs1 |
C |
A |
1: 63,200,108 (GRCm39) |
G268V |
probably damaging |
Het |
| Nfs1 |
A |
G |
2: 155,976,369 (GRCm39) |
V175A |
possibly damaging |
Het |
| Obsl1 |
C |
A |
1: 75,466,145 (GRCm39) |
A1528S |
possibly damaging |
Het |
| Or2z8 |
A |
G |
8: 72,811,938 (GRCm39) |
N138S |
probably benign |
Het |
| Or4a79 |
C |
T |
2: 89,551,706 (GRCm39) |
V250I |
probably benign |
Het |
| Or52z1 |
A |
T |
7: 103,436,688 (GRCm39) |
F265L |
possibly damaging |
Het |
| Or7a42 |
T |
G |
10: 78,791,931 (GRCm39) |
D297E |
probably null |
Het |
| Or8k39 |
C |
T |
2: 86,563,018 (GRCm39) |
|
probably null |
Het |
| Pcdhb8 |
A |
G |
18: 37,488,706 (GRCm39) |
D128G |
probably damaging |
Het |
| Pkp4 |
A |
T |
2: 59,172,449 (GRCm39) |
I522F |
probably damaging |
Het |
| Plod3 |
G |
A |
5: 137,019,654 (GRCm39) |
A398T |
probably benign |
Het |
| Pou4f3 |
A |
G |
18: 42,529,052 (GRCm39) |
M332V |
possibly damaging |
Het |
| Prox1 |
A |
G |
1: 189,885,669 (GRCm39) |
F593L |
probably damaging |
Het |
| Prrc2a |
G |
A |
17: 35,369,018 (GRCm39) |
P2006L |
probably damaging |
Het |
| Prss50 |
A |
G |
9: 110,692,864 (GRCm39) |
D328G |
probably damaging |
Het |
| Psmd6 |
C |
T |
14: 14,120,126 (GRCm38) |
S71N |
probably benign |
Het |
| Ptprd |
A |
G |
4: 76,009,769 (GRCm39) |
I764T |
probably benign |
Het |
| Ptprr |
C |
T |
10: 115,884,123 (GRCm39) |
A60V |
probably benign |
Het |
| Raet1e |
T |
A |
10: 22,057,199 (GRCm39) |
D174E |
probably damaging |
Het |
| Rbfox2 |
T |
C |
15: 76,976,018 (GRCm39) |
I308M |
probably benign |
Het |
| Rnf20 |
G |
C |
4: 49,649,962 (GRCm39) |
|
probably null |
Het |
| Rpap2 |
A |
T |
5: 107,768,113 (GRCm39) |
H317L |
probably benign |
Het |
| Rsph6a |
T |
A |
7: 18,799,783 (GRCm39) |
Y471* |
probably null |
Het |
| Sdhb |
A |
G |
4: 140,704,777 (GRCm39) |
H246R |
possibly damaging |
Het |
| Sh3bp5 |
C |
A |
14: 31,099,452 (GRCm39) |
R265L |
probably benign |
Het |
| Sin3b |
A |
C |
8: 73,452,271 (GRCm39) |
I126L |
probably benign |
Het |
| Skint2 |
G |
A |
4: 112,509,305 (GRCm39) |
A363T |
probably benign |
Het |
| Slc22a30 |
A |
G |
19: 8,321,768 (GRCm39) |
I432T |
probably benign |
Het |
| Slc2a2 |
G |
A |
3: 28,771,681 (GRCm39) |
|
probably null |
Het |
| Slco1a5 |
T |
C |
6: 142,194,533 (GRCm39) |
Y370C |
possibly damaging |
Het |
| Sltm |
A |
G |
9: 70,496,339 (GRCm39) |
H958R |
probably damaging |
Het |
| Smpdl3a |
C |
T |
10: 57,684,111 (GRCm39) |
H290Y |
probably damaging |
Het |
| Snrnp40 |
A |
G |
4: 130,256,549 (GRCm39) |
I91M |
probably damaging |
Het |
| Spag9 |
T |
A |
11: 93,939,343 (GRCm39) |
F91I |
probably damaging |
Het |
| Spag9 |
A |
T |
11: 93,939,342 (GRCm39) |
K90N |
possibly damaging |
Het |
| Stox1 |
A |
C |
10: 62,501,516 (GRCm39) |
I348S |
probably damaging |
Het |
| Sult1e1 |
A |
G |
5: 87,738,027 (GRCm39) |
V18A |
possibly damaging |
Het |
| Syne2 |
A |
G |
12: 75,945,941 (GRCm39) |
M338V |
probably benign |
Het |
| Tbc1d23 |
T |
A |
16: 57,012,991 (GRCm39) |
Q327L |
probably benign |
Het |
| Terf2 |
G |
T |
8: 107,803,307 (GRCm39) |
H425Q |
probably benign |
Het |
| Timd2 |
A |
T |
11: 46,568,094 (GRCm39) |
Y233* |
probably null |
Het |
| Tmem39a |
A |
G |
16: 38,411,524 (GRCm39) |
|
probably benign |
Het |
| Trappc10 |
T |
C |
10: 78,037,424 (GRCm39) |
D793G |
possibly damaging |
Het |
| Ugt1a10 |
TAAAAAAAAA |
TAAAAAAA |
1: 88,143,650 (GRCm39) |
|
probably benign |
Het |
| Unc93a |
T |
C |
17: 13,339,782 (GRCm39) |
|
probably null |
Het |
| Utrn |
T |
C |
10: 12,625,813 (GRCm39) |
T123A |
probably damaging |
Het |
| Vmn1r171 |
T |
C |
7: 23,332,369 (GRCm39) |
I198T |
probably benign |
Het |
| Vmn1r213 |
T |
A |
13: 23,196,016 (GRCm39) |
S200T |
probably damaging |
Het |
| Vmn2r108 |
T |
A |
17: 20,682,891 (GRCm39) |
D771V |
probably damaging |
Het |
| Wls |
C |
T |
3: 159,603,082 (GRCm39) |
T165I |
probably benign |
Het |
| Zc3h13 |
G |
A |
14: 75,576,863 (GRCm39) |
C1657Y |
probably damaging |
Het |
| Zdhhc5 |
T |
C |
2: 84,523,775 (GRCm39) |
K224E |
probably damaging |
Het |
| Zfp54 |
T |
A |
17: 21,654,402 (GRCm39) |
Y299N |
probably damaging |
Het |
| Zfp820 |
A |
T |
17: 22,037,966 (GRCm39) |
L454Q |
probably benign |
Het |
| Zfp960 |
T |
A |
17: 17,308,698 (GRCm39) |
F471I |
probably damaging |
Het |
| Zswim5 |
A |
G |
4: 116,830,169 (GRCm39) |
I515V |
probably benign |
Het |
| Zzef1 |
G |
T |
11: 72,750,449 (GRCm39) |
S919I |
probably benign |
Het |
|
| Other mutations in Cul9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00087:Cul9
|
APN |
17 |
46,836,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00330:Cul9
|
APN |
17 |
46,821,767 (GRCm39) |
splice site |
probably benign |
|
|
IGL00726:Cul9
|
APN |
17 |
46,839,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01020:Cul9
|
APN |
17 |
46,849,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01358:Cul9
|
APN |
17 |
46,849,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Cul9
|
APN |
17 |
46,839,572 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01781:Cul9
|
APN |
17 |
46,850,230 (GRCm39) |
missense |
probably benign |
|
|
IGL01873:Cul9
|
APN |
17 |
46,813,378 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02117:Cul9
|
APN |
17 |
46,851,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02300:Cul9
|
APN |
17 |
46,831,958 (GRCm39) |
splice site |
probably benign |
|
|
IGL02426:Cul9
|
APN |
17 |
46,834,184 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02427:Cul9
|
APN |
17 |
46,813,558 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02496:Cul9
|
APN |
17 |
46,851,302 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL03008:Cul9
|
APN |
17 |
46,813,623 (GRCm39) |
splice site |
probably benign |
|
|
IGL03059:Cul9
|
APN |
17 |
46,849,913 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03302:Cul9
|
APN |
17 |
46,837,566 (GRCm39) |
missense |
probably damaging |
0.98 |
|
bottlenose
|
UTSW |
17 |
46,811,770 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
flipper
|
UTSW |
17 |
46,836,818 (GRCm39) |
missense |
probably benign |
0.05 |
|
orca
|
UTSW |
17 |
46,836,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4340:Cul9
|
UTSW |
17 |
46,811,779 (GRCm39) |
small insertion |
probably benign |
|
|
FR4449:Cul9
|
UTSW |
17 |
46,811,782 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Cul9
|
UTSW |
17 |
46,811,784 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Cul9
|
UTSW |
17 |
46,811,772 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Cul9
|
UTSW |
17 |
46,811,779 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Cul9
|
UTSW |
17 |
46,811,776 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Cul9
|
UTSW |
17 |
46,811,774 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Cul9
|
UTSW |
17 |
46,811,782 (GRCm39) |
small insertion |
probably benign |
|
|
R0012:Cul9
|
UTSW |
17 |
46,849,436 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0079:Cul9
|
UTSW |
17 |
46,848,589 (GRCm39) |
nonsense |
probably null |
|
|
R0143:Cul9
|
UTSW |
17 |
46,837,336 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R0390:Cul9
|
UTSW |
17 |
46,839,515 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0401:Cul9
|
UTSW |
17 |
46,852,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0529:Cul9
|
UTSW |
17 |
46,831,394 (GRCm39) |
splice site |
probably benign |
|
|
R0815:Cul9
|
UTSW |
17 |
46,848,748 (GRCm39) |
splice site |
probably null |
|
|
R0863:Cul9
|
UTSW |
17 |
46,848,748 (GRCm39) |
splice site |
probably null |
|
|
R0972:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1173:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1216:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1217:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1261:Cul9
|
UTSW |
17 |
46,836,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1278:Cul9
|
UTSW |
17 |
46,811,775 (GRCm39) |
small deletion |
probably benign |
|
|
R1281:Cul9
|
UTSW |
17 |
46,822,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1349:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1372:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1403:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1403:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1467:Cul9
|
UTSW |
17 |
46,836,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1467:Cul9
|
UTSW |
17 |
46,836,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1482:Cul9
|
UTSW |
17 |
46,819,473 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1491:Cul9
|
UTSW |
17 |
46,849,490 (GRCm39) |
nonsense |
probably null |
|
|
R1618:Cul9
|
UTSW |
17 |
46,836,818 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1641:Cul9
|
UTSW |
17 |
46,854,486 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1679:Cul9
|
UTSW |
17 |
46,832,082 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1771:Cul9
|
UTSW |
17 |
46,848,738 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1803:Cul9
|
UTSW |
17 |
46,814,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Cul9
|
UTSW |
17 |
46,833,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2046:Cul9
|
UTSW |
17 |
46,854,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2056:Cul9
|
UTSW |
17 |
46,854,298 (GRCm39) |
missense |
probably benign |
|
|
R2088:Cul9
|
UTSW |
17 |
46,837,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2415:Cul9
|
UTSW |
17 |
46,854,364 (GRCm39) |
missense |
probably benign |
|
|
R2925:Cul9
|
UTSW |
17 |
46,821,907 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2964:Cul9
|
UTSW |
17 |
46,813,154 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2965:Cul9
|
UTSW |
17 |
46,813,154 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3690:Cul9
|
UTSW |
17 |
46,814,957 (GRCm39) |
splice site |
probably null |
|
|
R3847:Cul9
|
UTSW |
17 |
46,836,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4437:Cul9
|
UTSW |
17 |
46,813,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Cul9
|
UTSW |
17 |
46,849,262 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4540:Cul9
|
UTSW |
17 |
46,814,015 (GRCm39) |
missense |
probably null |
0.98 |
|
R4555:Cul9
|
UTSW |
17 |
46,812,755 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4604:Cul9
|
UTSW |
17 |
46,841,072 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4646:Cul9
|
UTSW |
17 |
46,849,943 (GRCm39) |
nonsense |
probably null |
|
|
R4822:Cul9
|
UTSW |
17 |
46,840,977 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4964:Cul9
|
UTSW |
17 |
46,849,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4965:Cul9
|
UTSW |
17 |
46,849,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5027:Cul9
|
UTSW |
17 |
46,811,708 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5185:Cul9
|
UTSW |
17 |
46,836,758 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5237:Cul9
|
UTSW |
17 |
46,854,393 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5278:Cul9
|
UTSW |
17 |
46,821,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5361:Cul9
|
UTSW |
17 |
46,811,775 (GRCm39) |
small deletion |
probably benign |
|
|
R5455:Cul9
|
UTSW |
17 |
46,821,772 (GRCm39) |
splice site |
probably null |
|
|
R5592:Cul9
|
UTSW |
17 |
46,831,517 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5597:Cul9
|
UTSW |
17 |
46,813,591 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R5613:Cul9
|
UTSW |
17 |
46,814,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6122:Cul9
|
UTSW |
17 |
46,832,854 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6135:Cul9
|
UTSW |
17 |
46,832,379 (GRCm39) |
missense |
probably benign |
|
|
R6352:Cul9
|
UTSW |
17 |
46,822,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6376:Cul9
|
UTSW |
17 |
46,819,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6868:Cul9
|
UTSW |
17 |
46,833,109 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6898:Cul9
|
UTSW |
17 |
46,821,952 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7090:Cul9
|
UTSW |
17 |
46,811,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7193:Cul9
|
UTSW |
17 |
46,849,423 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7221:Cul9
|
UTSW |
17 |
46,839,491 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7291:Cul9
|
UTSW |
17 |
46,851,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7320:Cul9
|
UTSW |
17 |
46,821,835 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7348:Cul9
|
UTSW |
17 |
46,821,919 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7463:Cul9
|
UTSW |
17 |
46,831,402 (GRCm39) |
splice site |
probably null |
|
|
R7480:Cul9
|
UTSW |
17 |
46,848,738 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7573:Cul9
|
UTSW |
17 |
46,830,836 (GRCm39) |
missense |
probably benign |
|
|
R7582:Cul9
|
UTSW |
17 |
46,821,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7605:Cul9
|
UTSW |
17 |
46,852,658 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7684:Cul9
|
UTSW |
17 |
46,820,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7830:Cul9
|
UTSW |
17 |
46,851,237 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7834:Cul9
|
UTSW |
17 |
46,836,630 (GRCm39) |
splice site |
probably null |
|
|
R8131:Cul9
|
UTSW |
17 |
46,822,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8192:Cul9
|
UTSW |
17 |
46,849,273 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8231:Cul9
|
UTSW |
17 |
46,831,427 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8248:Cul9
|
UTSW |
17 |
46,840,940 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8504:Cul9
|
UTSW |
17 |
46,814,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8550:Cul9
|
UTSW |
17 |
46,830,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8716:Cul9
|
UTSW |
17 |
46,838,840 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8769:Cul9
|
UTSW |
17 |
46,832,828 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8893:Cul9
|
UTSW |
17 |
46,811,775 (GRCm39) |
small deletion |
probably benign |
|
|
R8904:Cul9
|
UTSW |
17 |
46,831,427 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8936:Cul9
|
UTSW |
17 |
46,839,528 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8972:Cul9
|
UTSW |
17 |
46,854,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9003:Cul9
|
UTSW |
17 |
46,836,001 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9012:Cul9
|
UTSW |
17 |
46,854,447 (GRCm39) |
missense |
probably benign |
|
|
R9056:Cul9
|
UTSW |
17 |
46,854,696 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9071:Cul9
|
UTSW |
17 |
46,837,379 (GRCm39) |
missense |
probably benign |
|
|
R9162:Cul9
|
UTSW |
17 |
46,837,529 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9476:Cul9
|
UTSW |
17 |
46,821,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9526:Cul9
|
UTSW |
17 |
46,841,026 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9563:Cul9
|
UTSW |
17 |
46,820,897 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9568:Cul9
|
UTSW |
17 |
46,831,044 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9610:Cul9
|
UTSW |
17 |
46,830,823 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9611:Cul9
|
UTSW |
17 |
46,830,823 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9705:Cul9
|
UTSW |
17 |
46,854,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Cul9
|
UTSW |
17 |
46,850,224 (GRCm39) |
missense |
probably benign |
0.18 |
|
RF011:Cul9
|
UTSW |
17 |
46,811,774 (GRCm39) |
small insertion |
probably benign |
|
|
RF016:Cul9
|
UTSW |
17 |
46,811,789 (GRCm39) |
nonsense |
probably null |
|
|
RF026:Cul9
|
UTSW |
17 |
46,811,795 (GRCm39) |
nonsense |
probably null |
|
|
RF027:Cul9
|
UTSW |
17 |
46,811,774 (GRCm39) |
small insertion |
probably benign |
|
|
RF030:Cul9
|
UTSW |
17 |
46,811,795 (GRCm39) |
small insertion |
probably benign |
|
|
RF033:Cul9
|
UTSW |
17 |
46,811,780 (GRCm39) |
small insertion |
probably benign |
|
|
RF039:Cul9
|
UTSW |
17 |
46,811,780 (GRCm39) |
small insertion |
probably benign |
|
|
RF041:Cul9
|
UTSW |
17 |
46,811,780 (GRCm39) |
nonsense |
probably null |
|
|
RF042:Cul9
|
UTSW |
17 |
46,851,541 (GRCm39) |
frame shift |
probably null |
|
|
RF057:Cul9
|
UTSW |
17 |
46,811,789 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Cul9
|
UTSW |
17 |
46,831,511 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Cul9
|
UTSW |
17 |
46,831,502 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Cul9
|
UTSW |
17 |
46,848,723 (GRCm39) |
missense |
probably benign |
0.14 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTCAGACACTGGGAATCCC -3'
(R):5'- TGCAGAGTCCCTCAGTAGAG -3'
Sequencing Primer
(F):5'- GGAATCCCCTCTCCCATGAC -3'
(R):5'- TCCAACGTGCCCAGTGATCAG -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation