Incidental Mutation 'R4816:Cep152'
| ID |
369768 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cep152
|
| Ensembl Gene |
ENSMUSG00000068394 |
| Gene Name |
centrosomal protein 152 |
| Synonyms |
|
| MMRRC Submission |
042434-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4816 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
125405008-125467033 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 125405674 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Arginine
at position 1619
(S1619R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000087208
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000089776]
|
| AlphaFold |
A2AUM9 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000089776
AA Change: S1619R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000087208
Gene: ENSMUSG00000068394
AA Change: S1619R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
106 |
124 |
N/A |
INTRINSIC |
|
coiled coil region
|
228 |
481 |
N/A |
INTRINSIC |
|
low complexity region
|
582 |
593 |
N/A |
INTRINSIC |
|
coiled coil region
|
602 |
651 |
N/A |
INTRINSIC |
|
coiled coil region
|
692 |
770 |
N/A |
INTRINSIC |
|
low complexity region
|
780 |
793 |
N/A |
INTRINSIC |
|
coiled coil region
|
835 |
868 |
N/A |
INTRINSIC |
|
coiled coil region
|
954 |
1038 |
N/A |
INTRINSIC |
|
coiled coil region
|
1205 |
1277 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.3511 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.0%
|
| Validation Efficiency |
97% (113/116) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
PHENOTYPE: Embryos homozygous for a null allele exhibit reduced numbers of centrosomes and cilia, increased apoptosis, and midgestation lethality. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 107 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc8 |
C |
A |
7: 45,754,131 (GRCm39) |
A1562S |
probably benign |
Het |
| Adam30 |
C |
A |
3: 98,070,061 (GRCm39) |
D631E |
possibly damaging |
Het |
| Adgrv1 |
T |
C |
13: 81,676,793 (GRCm39) |
T2013A |
probably damaging |
Het |
| Ark2n |
A |
T |
18: 77,740,995 (GRCm39) |
|
probably null |
Het |
| Baiap3 |
T |
A |
17: 25,466,269 (GRCm39) |
|
probably benign |
Het |
| Bicra |
T |
C |
7: 15,722,831 (GRCm39) |
T229A |
possibly damaging |
Het |
| C1qbp |
A |
G |
11: 70,873,190 (GRCm39) |
|
probably benign |
Het |
| C2cd3 |
C |
A |
7: 100,040,226 (GRCm39) |
T265K |
probably benign |
Het |
| Cacna1s |
T |
A |
1: 136,043,007 (GRCm39) |
I1331K |
possibly damaging |
Het |
| Cdadc1 |
AGACGGA |
AGA |
14: 59,806,440 (GRCm39) |
|
probably null |
Het |
| Cdcp2 |
A |
G |
4: 106,963,969 (GRCm39) |
Y273C |
probably damaging |
Het |
| Cdh23 |
A |
C |
10: 60,244,856 (GRCm39) |
V1013G |
possibly damaging |
Het |
| Celf3 |
T |
A |
3: 94,386,529 (GRCm39) |
I39N |
probably damaging |
Het |
| Cfap36 |
A |
G |
11: 29,195,108 (GRCm39) |
I42T |
probably damaging |
Het |
| Cfap61 |
G |
T |
2: 145,985,020 (GRCm39) |
V955L |
probably damaging |
Het |
| Cit |
G |
A |
5: 116,046,750 (GRCm39) |
D388N |
probably damaging |
Het |
| Clca3a2 |
T |
C |
3: 144,516,613 (GRCm39) |
M328V |
probably benign |
Het |
| Cntn4 |
A |
T |
6: 106,527,458 (GRCm39) |
I447L |
probably benign |
Het |
| Csmd3 |
T |
C |
15: 47,721,330 (GRCm39) |
T1538A |
possibly damaging |
Het |
| Cstf1 |
A |
G |
2: 172,214,905 (GRCm39) |
K9E |
probably damaging |
Het |
| Dip2c |
T |
A |
13: 9,625,186 (GRCm39) |
M560K |
probably benign |
Het |
| Dsg1a |
A |
T |
18: 20,466,779 (GRCm39) |
T550S |
probably benign |
Het |
| Dtnb |
A |
G |
12: 3,799,505 (GRCm39) |
E460G |
probably damaging |
Het |
| Dus1l |
GAGGTAAG |
GAG |
11: 120,680,584 (GRCm39) |
|
probably benign |
Het |
| Efl1 |
T |
A |
7: 82,320,927 (GRCm39) |
V120E |
probably damaging |
Het |
| Fbxl13 |
T |
C |
5: 21,689,001 (GRCm39) |
Y769C |
probably benign |
Het |
| Fcho2 |
T |
C |
13: 98,942,874 (GRCm39) |
Y22C |
probably damaging |
Het |
| Flacc1 |
G |
A |
1: 58,709,567 (GRCm39) |
A196V |
probably benign |
Het |
| Gbp3 |
T |
C |
3: 142,273,335 (GRCm39) |
V294A |
probably damaging |
Het |
| Gls |
A |
G |
1: 52,239,104 (GRCm39) |
|
probably benign |
Het |
| Gm15130 |
A |
T |
2: 110,965,714 (GRCm39) |
|
probably benign |
Het |
| Gm6185 |
A |
T |
1: 161,040,728 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr171 |
T |
A |
3: 59,005,517 (GRCm39) |
H86L |
probably damaging |
Het |
| Gpr179 |
T |
C |
11: 97,230,074 (GRCm39) |
T694A |
probably damaging |
Het |
| H2-Aa |
A |
T |
17: 34,502,794 (GRCm39) |
V124E |
probably damaging |
Het |
| H2bc13 |
A |
G |
13: 21,900,135 (GRCm39) |
M60T |
probably benign |
Het |
| H2-M5 |
A |
G |
17: 37,300,309 (GRCm39) |
|
probably benign |
Het |
| Igf2r |
A |
T |
17: 12,902,984 (GRCm39) |
N2355K |
probably damaging |
Het |
| Il9r |
A |
C |
11: 32,142,654 (GRCm39) |
S295A |
possibly damaging |
Het |
| Ipo9 |
T |
C |
1: 135,334,288 (GRCm39) |
T313A |
probably benign |
Het |
| Kalrn |
C |
T |
16: 34,334,389 (GRCm39) |
|
probably benign |
Het |
| Lama3 |
G |
A |
18: 12,610,661 (GRCm39) |
V1175M |
possibly damaging |
Het |
| Lhpp |
T |
A |
7: 132,272,104 (GRCm39) |
C242* |
probably null |
Het |
| Lipe |
A |
G |
7: 25,079,568 (GRCm39) |
S1013P |
probably damaging |
Het |
| Lrrc25 |
C |
T |
8: 71,070,726 (GRCm39) |
T169I |
probably benign |
Het |
| Lrrc39 |
T |
C |
3: 116,362,515 (GRCm39) |
|
probably null |
Het |
| Lrrd1 |
T |
A |
5: 3,901,126 (GRCm39) |
L477* |
probably null |
Het |
| Lrriq4 |
A |
G |
3: 30,714,196 (GRCm39) |
I515V |
possibly damaging |
Het |
| Magel2 |
A |
G |
7: 62,030,840 (GRCm39) |
Y1248C |
unknown |
Het |
| Maml1 |
G |
T |
11: 50,149,162 (GRCm39) |
N859K |
possibly damaging |
Het |
| Mdm1 |
A |
T |
10: 117,982,782 (GRCm39) |
H139L |
possibly damaging |
Het |
| Mef2d |
C |
T |
3: 88,075,397 (GRCm39) |
P420S |
possibly damaging |
Het |
| Mgat4b |
A |
G |
11: 50,101,848 (GRCm39) |
K38E |
probably benign |
Het |
| Mtmr4 |
T |
C |
11: 87,494,923 (GRCm39) |
V405A |
probably damaging |
Het |
| Naip5 |
G |
A |
13: 100,356,195 (GRCm39) |
T1140M |
probably benign |
Het |
| Naip5 |
T |
C |
13: 100,356,204 (GRCm39) |
Q1137R |
probably benign |
Het |
| Naip5 |
G |
A |
13: 100,356,189 (GRCm39) |
S1142F |
probably benign |
Het |
| Nfe2l3 |
T |
C |
6: 51,433,604 (GRCm39) |
S239P |
probably damaging |
Het |
| Nlrp3 |
A |
G |
11: 59,439,127 (GRCm39) |
I235V |
probably benign |
Het |
| Nyap2 |
T |
A |
1: 81,219,028 (GRCm39) |
L318Q |
probably damaging |
Het |
| Nynrin |
G |
A |
14: 56,109,458 (GRCm39) |
V1522M |
probably damaging |
Het |
| Oog3 |
A |
G |
4: 143,885,731 (GRCm39) |
L289P |
probably damaging |
Het |
| Or52n20 |
C |
T |
7: 104,319,942 (GRCm39) |
P11L |
probably benign |
Het |
| Or5b107 |
A |
G |
19: 13,142,488 (GRCm39) |
I37V |
probably benign |
Het |
| Or6c69b |
T |
C |
10: 129,627,308 (GRCm39) |
D50G |
probably damaging |
Het |
| Or8b12b |
T |
A |
9: 37,684,726 (GRCm39) |
M257K |
possibly damaging |
Het |
| Or9g20 |
A |
T |
2: 85,630,391 (GRCm39) |
N74K |
probably benign |
Het |
| Pax6 |
T |
C |
2: 105,514,129 (GRCm39) |
|
probably benign |
Het |
| Pbrm1 |
G |
A |
14: 30,832,405 (GRCm39) |
R1441K |
probably benign |
Het |
| Pcdha9 |
C |
T |
18: 37,132,511 (GRCm39) |
R527W |
probably damaging |
Het |
| Pcdhb17 |
T |
C |
18: 37,620,450 (GRCm39) |
S747P |
probably benign |
Het |
| Pcnx3 |
A |
C |
19: 5,738,023 (GRCm39) |
|
probably null |
Het |
| Pds5a |
A |
T |
5: 65,808,632 (GRCm39) |
V413E |
probably damaging |
Het |
| Phpt1 |
G |
T |
2: 25,464,332 (GRCm39) |
|
probably benign |
Het |
| Phykpl |
A |
G |
11: 51,483,780 (GRCm39) |
E220G |
probably benign |
Het |
| Pias2 |
T |
C |
18: 77,193,587 (GRCm39) |
|
probably null |
Het |
| Pkhd1 |
T |
A |
1: 20,269,639 (GRCm39) |
I3302L |
probably damaging |
Het |
| Poli |
A |
G |
18: 70,655,822 (GRCm39) |
L241P |
probably damaging |
Het |
| Ppm1h |
T |
A |
10: 122,515,284 (GRCm39) |
I65N |
possibly damaging |
Het |
| Ptpn14 |
T |
C |
1: 189,588,997 (GRCm39) |
L954P |
probably damaging |
Het |
| Pxk |
T |
G |
14: 8,136,893 (GRCm38) |
M138R |
probably damaging |
Het |
| Rasl11b |
G |
T |
5: 74,359,058 (GRCm39) |
D188Y |
probably damaging |
Het |
| Rtraf |
A |
G |
14: 19,872,644 (GRCm39) |
F59S |
probably benign |
Het |
| Sanbr |
A |
C |
11: 23,565,243 (GRCm39) |
I248S |
possibly damaging |
Het |
| Serpinb5 |
G |
T |
1: 106,800,069 (GRCm39) |
L86F |
probably damaging |
Het |
| Setdb2 |
G |
A |
14: 59,651,095 (GRCm39) |
T412I |
probably benign |
Het |
| Shank2 |
C |
A |
7: 143,606,043 (GRCm39) |
N75K |
probably damaging |
Het |
| Shank3 |
T |
A |
15: 89,427,318 (GRCm39) |
I791N |
probably damaging |
Het |
| Slc25a13 |
T |
A |
6: 6,114,274 (GRCm39) |
M213L |
possibly damaging |
Het |
| Slc25a21 |
T |
C |
12: 56,760,623 (GRCm39) |
Y298C |
probably damaging |
Het |
| Slc34a2 |
A |
G |
5: 53,226,362 (GRCm39) |
N495S |
probably damaging |
Het |
| Smc2 |
A |
G |
4: 52,451,231 (GRCm39) |
T292A |
probably benign |
Het |
| Spag9 |
T |
C |
11: 93,939,425 (GRCm39) |
|
probably benign |
Het |
| Tas2r113 |
C |
T |
6: 132,870,745 (GRCm39) |
P258S |
probably benign |
Het |
| Tbkbp1 |
T |
C |
11: 97,029,567 (GRCm39) |
S530G |
probably benign |
Het |
| Tenm2 |
A |
G |
11: 35,918,117 (GRCm39) |
V1881A |
probably damaging |
Het |
| Tm9sf1 |
C |
T |
14: 55,878,606 (GRCm39) |
R262Q |
possibly damaging |
Het |
| Tmcc3 |
G |
T |
10: 94,414,646 (GRCm39) |
G147V |
possibly damaging |
Het |
| Trim38 |
A |
T |
13: 23,972,264 (GRCm39) |
E195V |
probably damaging |
Het |
| Try5 |
T |
C |
6: 41,290,349 (GRCm39) |
Y45C |
probably benign |
Het |
| Umad1 |
A |
C |
6: 8,457,462 (GRCm39) |
|
probably benign |
Het |
| Vmn2r105 |
T |
C |
17: 20,428,953 (GRCm39) |
I708V |
probably benign |
Het |
| Zc3h12d |
A |
T |
10: 7,743,711 (GRCm39) |
S494C |
probably damaging |
Het |
| Zeb2 |
A |
G |
2: 44,887,780 (GRCm39) |
S382P |
probably damaging |
Het |
| Zfc3h1 |
A |
G |
10: 115,251,599 (GRCm39) |
S1304G |
probably benign |
Het |
| Zfp287 |
G |
T |
11: 62,605,074 (GRCm39) |
T611K |
probably damaging |
Het |
| Zfp534 |
G |
A |
4: 147,758,743 (GRCm39) |
T642I |
possibly damaging |
Het |
|
| Other mutations in Cep152 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00155:Cep152
|
APN |
2 |
125,405,808 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00561:Cep152
|
APN |
2 |
125,405,643 (GRCm39) |
nonsense |
probably null |
|
|
IGL01082:Cep152
|
APN |
2 |
125,411,465 (GRCm39) |
splice site |
probably benign |
|
|
IGL01420:Cep152
|
APN |
2 |
125,405,572 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL01832:Cep152
|
APN |
2 |
125,460,414 (GRCm39) |
nonsense |
probably null |
|
|
IGL02106:Cep152
|
APN |
2 |
125,444,856 (GRCm39) |
splice site |
probably null |
|
|
IGL02124:Cep152
|
APN |
2 |
125,405,381 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL02349:Cep152
|
APN |
2 |
125,436,876 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02541:Cep152
|
APN |
2 |
125,447,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02659:Cep152
|
APN |
2 |
125,421,469 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02711:Cep152
|
APN |
2 |
125,405,862 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02737:Cep152
|
APN |
2 |
125,428,394 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL03060:Cep152
|
APN |
2 |
125,461,907 (GRCm39) |
splice site |
probably benign |
|
|
IGL03095:Cep152
|
APN |
2 |
125,460,371 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03186:Cep152
|
APN |
2 |
125,405,895 (GRCm39) |
missense |
probably benign |
|
|
IGL03306:Cep152
|
APN |
2 |
125,447,328 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0034:Cep152
|
UTSW |
2 |
125,425,813 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0034:Cep152
|
UTSW |
2 |
125,425,813 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0079:Cep152
|
UTSW |
2 |
125,460,373 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0244:Cep152
|
UTSW |
2 |
125,406,134 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0390:Cep152
|
UTSW |
2 |
125,418,789 (GRCm39) |
splice site |
probably benign |
|
|
R0462:Cep152
|
UTSW |
2 |
125,425,854 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0480:Cep152
|
UTSW |
2 |
125,423,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0595:Cep152
|
UTSW |
2 |
125,436,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0973:Cep152
|
UTSW |
2 |
125,436,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0973:Cep152
|
UTSW |
2 |
125,436,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1634:Cep152
|
UTSW |
2 |
125,425,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1664:Cep152
|
UTSW |
2 |
125,408,174 (GRCm39) |
missense |
probably benign |
0.38 |
|
R1693:Cep152
|
UTSW |
2 |
125,408,174 (GRCm39) |
missense |
probably benign |
0.38 |
|
R1887:Cep152
|
UTSW |
2 |
125,462,225 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1930:Cep152
|
UTSW |
2 |
125,460,291 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2178:Cep152
|
UTSW |
2 |
125,421,954 (GRCm39) |
splice site |
probably null |
|
|
R2225:Cep152
|
UTSW |
2 |
125,423,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2324:Cep152
|
UTSW |
2 |
125,405,382 (GRCm39) |
missense |
probably benign |
0.38 |
|
R2416:Cep152
|
UTSW |
2 |
125,406,092 (GRCm39) |
nonsense |
probably null |
|
|
R2845:Cep152
|
UTSW |
2 |
125,429,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3753:Cep152
|
UTSW |
2 |
125,466,972 (GRCm39) |
unclassified |
probably benign |
|
|
R4212:Cep152
|
UTSW |
2 |
125,461,921 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4304:Cep152
|
UTSW |
2 |
125,405,643 (GRCm39) |
nonsense |
probably null |
|
|
R4371:Cep152
|
UTSW |
2 |
125,454,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4399:Cep152
|
UTSW |
2 |
125,429,900 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4536:Cep152
|
UTSW |
2 |
125,444,867 (GRCm39) |
splice site |
probably null |
|
|
R4713:Cep152
|
UTSW |
2 |
125,429,868 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R4777:Cep152
|
UTSW |
2 |
125,406,015 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4779:Cep152
|
UTSW |
2 |
125,410,812 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4785:Cep152
|
UTSW |
2 |
125,428,249 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4847:Cep152
|
UTSW |
2 |
125,460,394 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R4898:Cep152
|
UTSW |
2 |
125,428,301 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4934:Cep152
|
UTSW |
2 |
125,453,016 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4997:Cep152
|
UTSW |
2 |
125,428,271 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5068:Cep152
|
UTSW |
2 |
125,413,736 (GRCm39) |
missense |
probably benign |
0.25 |
|
R5183:Cep152
|
UTSW |
2 |
125,408,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5198:Cep152
|
UTSW |
2 |
125,429,544 (GRCm39) |
missense |
probably benign |
|
|
R5261:Cep152
|
UTSW |
2 |
125,406,125 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5272:Cep152
|
UTSW |
2 |
125,452,950 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5284:Cep152
|
UTSW |
2 |
125,421,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6029:Cep152
|
UTSW |
2 |
125,405,552 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6155:Cep152
|
UTSW |
2 |
125,423,620 (GRCm39) |
missense |
probably benign |
|
|
R6239:Cep152
|
UTSW |
2 |
125,421,332 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6590:Cep152
|
UTSW |
2 |
125,406,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6690:Cep152
|
UTSW |
2 |
125,406,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6754:Cep152
|
UTSW |
2 |
125,429,588 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6798:Cep152
|
UTSW |
2 |
125,408,447 (GRCm39) |
splice site |
probably null |
|
|
R6816:Cep152
|
UTSW |
2 |
125,436,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6977:Cep152
|
UTSW |
2 |
125,410,742 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7125:Cep152
|
UTSW |
2 |
125,408,593 (GRCm39) |
nonsense |
probably null |
|
|
R7146:Cep152
|
UTSW |
2 |
125,456,325 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7588:Cep152
|
UTSW |
2 |
125,411,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7852:Cep152
|
UTSW |
2 |
125,432,033 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7883:Cep152
|
UTSW |
2 |
125,454,978 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8047:Cep152
|
UTSW |
2 |
125,406,247 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8082:Cep152
|
UTSW |
2 |
125,428,313 (GRCm39) |
missense |
probably benign |
|
|
R8680:Cep152
|
UTSW |
2 |
125,406,131 (GRCm39) |
nonsense |
probably null |
|
|
R8739:Cep152
|
UTSW |
2 |
125,461,975 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8744:Cep152
|
UTSW |
2 |
125,436,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8896:Cep152
|
UTSW |
2 |
125,408,155 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8924:Cep152
|
UTSW |
2 |
125,444,778 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8971:Cep152
|
UTSW |
2 |
125,421,770 (GRCm39) |
nonsense |
probably null |
|
|
R9004:Cep152
|
UTSW |
2 |
125,453,020 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9149:Cep152
|
UTSW |
2 |
125,463,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9149:Cep152
|
UTSW |
2 |
125,461,803 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9161:Cep152
|
UTSW |
2 |
125,408,574 (GRCm39) |
nonsense |
probably null |
|
|
R9239:Cep152
|
UTSW |
2 |
125,425,830 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9249:Cep152
|
UTSW |
2 |
125,405,904 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9258:Cep152
|
UTSW |
2 |
125,421,356 (GRCm39) |
nonsense |
probably null |
|
|
R9619:Cep152
|
UTSW |
2 |
125,436,827 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9643:Cep152
|
UTSW |
2 |
125,406,150 (GRCm39) |
nonsense |
probably null |
|
|
R9775:Cep152
|
UTSW |
2 |
125,423,660 (GRCm39) |
nonsense |
probably null |
|
|
X0009:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0010:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0011:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0014:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0017:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0021:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0022:Cep152
|
UTSW |
2 |
125,461,983 (GRCm39) |
missense |
probably benign |
0.07 |
|
X0023:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0028:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0033:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0064:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0067:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Cep152
|
UTSW |
2 |
125,425,891 (GRCm39) |
missense |
probably benign |
0.23 |
|
Z1177:Cep152
|
UTSW |
2 |
125,461,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Cep152
|
UTSW |
2 |
125,456,244 (GRCm39) |
missense |
probably benign |
0.33 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGAGTTGCACCCATCTTCC -3'
(R):5'- ATCTCAGAGTCCAGGCACAC -3'
Sequencing Primer
(F):5'- CCTTGTTGGGAATGCAGGG -3'
(R):5'- CCCTGAGAAGTCCCAGTGAAATG -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation