Incidental Mutation 'R4817:Nckap5'
| ID |
369870 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nckap5
|
| Ensembl Gene |
ENSMUSG00000049690 |
| Gene Name |
NCK-associated protein 5 |
| Synonyms |
LOC380609, D130011D22Rik, E030049G20Rik |
| MMRRC Submission |
042435-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4817 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
125841373-126758529 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 125954952 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 469
(D469E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000062229
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057846]
[ENSMUST00000094609]
[ENSMUST00000094610]
[ENSMUST00000112583]
[ENSMUST00000161954]
[ENSMUST00000162877]
|
| AlphaFold |
E9QAE1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000057846
AA Change: D469E
PolyPhen 2
Score 0.682 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000062229
Gene: ENSMUSG00000049690
AA Change: D469E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
755 |
771 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1181 |
1200 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1298 |
1602 |
1.8e-120 |
PFAM |
|
low complexity region
|
1728 |
1742 |
N/A |
INTRINSIC |
|
low complexity region
|
1757 |
1771 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094609
|
| SMART Domains |
Protein: ENSMUSP00000092192
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
113 |
364 |
3.6e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094610
|
| SMART Domains |
Protein: ENSMUSP00000092193
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
1 |
101 |
8.8e-42 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112583
AA Change: D601E
PolyPhen 2
Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000108202
Gene: ENSMUSG00000049690
AA Change: D601E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
coiled coil region
|
176 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
453 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
887 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1332 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1431 |
1733 |
5.3e-119 |
PFAM |
|
low complexity region
|
1860 |
1874 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1903 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159934
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161954
AA Change: D533E
PolyPhen 2
Score 0.048 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000125624
Gene: ENSMUSG00000049690
AA Change: D533E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
385 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1035 |
N/A |
INTRINSIC |
|
low complexity region
|
1134 |
1149 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1264 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1362 |
1666 |
2.1e-120 |
PFAM |
|
low complexity region
|
1792 |
1806 |
N/A |
INTRINSIC |
|
low complexity region
|
1821 |
1835 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162877
|
| SMART Domains |
Protein: ENSMUSP00000124748
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
9 |
296 |
6e-36 |
PFAM |
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
96% (108/112) |
| Allele List at MGI |
All alleles(1) : Gene trapped(1) |
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acp2 |
T |
A |
2: 91,033,963 (GRCm39) |
D44E |
probably damaging |
Het |
| Acp5 |
T |
C |
9: 22,038,379 (GRCm39) |
I307M |
probably benign |
Het |
| Ahsa1 |
A |
G |
12: 87,319,940 (GRCm39) |
D245G |
possibly damaging |
Het |
| Ankrd40 |
A |
G |
11: 94,230,459 (GRCm39) |
K316E |
probably benign |
Het |
| Apol9b |
G |
A |
15: 77,620,088 (GRCm39) |
E295K |
possibly damaging |
Het |
| Aqp4 |
C |
A |
18: 15,532,815 (GRCm39) |
G93C |
probably damaging |
Het |
| Arhgap21 |
A |
G |
2: 20,854,967 (GRCm39) |
V1465A |
probably benign |
Het |
| Arhgap5 |
C |
T |
12: 52,565,992 (GRCm39) |
P988S |
possibly damaging |
Het |
| Asxl3 |
A |
C |
18: 22,658,511 (GRCm39) |
K2174Q |
probably damaging |
Het |
| Brf1 |
A |
T |
12: 112,935,921 (GRCm39) |
I250N |
probably damaging |
Het |
| Calm1 |
A |
G |
12: 100,169,832 (GRCm39) |
|
probably null |
Het |
| Ccdc33 |
C |
T |
9: 57,974,818 (GRCm39) |
V352M |
probably damaging |
Het |
| Ccdc88a |
G |
T |
11: 29,410,907 (GRCm39) |
K464N |
probably benign |
Het |
| Cdadc1 |
AGACGGA |
AGA |
14: 59,806,440 (GRCm39) |
|
probably null |
Het |
| Cdc25b |
T |
A |
2: 131,035,223 (GRCm39) |
I327N |
probably damaging |
Het |
| Cenpf |
G |
A |
1: 189,414,566 (GRCm39) |
H184Y |
possibly damaging |
Het |
| Cimap1d |
G |
A |
10: 79,475,851 (GRCm39) |
P238S |
probably damaging |
Het |
| Col6a5 |
G |
A |
9: 105,811,497 (GRCm39) |
T674I |
unknown |
Het |
| Creg2 |
A |
T |
1: 39,662,358 (GRCm39) |
M258K |
probably damaging |
Het |
| Csf3r |
T |
A |
4: 125,931,449 (GRCm39) |
Y477* |
probably null |
Het |
| Cyp3a44 |
T |
A |
5: 145,740,565 (GRCm39) |
Y25F |
possibly damaging |
Het |
| Degs2 |
T |
A |
12: 108,655,325 (GRCm39) |
R283* |
probably null |
Het |
| Dido1 |
T |
C |
2: 180,303,209 (GRCm39) |
N1565S |
probably benign |
Het |
| Dnah6 |
A |
T |
6: 72,999,407 (GRCm39) |
M4008K |
probably benign |
Het |
| Dnmbp |
C |
A |
19: 43,838,411 (GRCm39) |
G1138V |
probably benign |
Het |
| Drosha |
A |
C |
15: 12,914,133 (GRCm39) |
H1136P |
probably damaging |
Het |
| Duox2 |
T |
G |
2: 122,126,996 (GRCm39) |
N173T |
probably damaging |
Het |
| Dync1li1 |
T |
G |
9: 114,534,162 (GRCm39) |
I87M |
probably benign |
Het |
| E2f8 |
A |
C |
7: 48,517,494 (GRCm39) |
S770A |
probably benign |
Het |
| Efemp1 |
A |
G |
11: 28,876,241 (GRCm39) |
T469A |
probably damaging |
Het |
| Eif3f |
A |
T |
7: 108,536,982 (GRCm39) |
T136S |
probably damaging |
Het |
| Enpp5 |
T |
C |
17: 44,391,871 (GRCm39) |
*46R |
probably null |
Het |
| Epb41l4b |
A |
G |
4: 57,103,428 (GRCm39) |
V136A |
probably damaging |
Het |
| Fam186a |
A |
C |
15: 99,831,419 (GRCm39) |
|
probably benign |
Het |
| Flt4 |
A |
G |
11: 49,516,242 (GRCm39) |
Y115C |
probably damaging |
Het |
| Gal |
T |
A |
19: 3,461,126 (GRCm39) |
|
probably null |
Het |
| Galnt3 |
C |
T |
2: 65,923,883 (GRCm39) |
V462I |
possibly damaging |
Het |
| Gas2l1 |
A |
G |
11: 5,011,429 (GRCm39) |
S467P |
possibly damaging |
Het |
| Gbx1 |
A |
G |
5: 24,731,204 (GRCm39) |
L204P |
probably damaging |
Het |
| Gle1 |
T |
A |
2: 29,826,223 (GRCm39) |
S101T |
probably benign |
Het |
| Gltpd2 |
A |
C |
11: 70,410,303 (GRCm39) |
Q87P |
probably damaging |
Het |
| Gm12789 |
T |
A |
4: 101,846,079 (GRCm39) |
D113E |
probably damaging |
Het |
| Grin3b |
G |
A |
10: 79,812,732 (GRCm39) |
G936R |
probably benign |
Het |
| Gtf3c2 |
C |
T |
5: 31,331,434 (GRCm39) |
|
probably null |
Het |
| Gvin3 |
T |
A |
7: 106,200,437 (GRCm39) |
|
noncoding transcript |
Het |
| Klhl28 |
T |
C |
12: 65,004,043 (GRCm39) |
T157A |
probably benign |
Het |
| Kmt2a |
A |
G |
9: 44,732,763 (GRCm39) |
|
probably benign |
Het |
| Lamp1 |
A |
G |
8: 13,222,541 (GRCm39) |
T242A |
probably benign |
Het |
| Lhfpl5 |
T |
G |
17: 28,795,300 (GRCm39) |
I109S |
possibly damaging |
Het |
| Lhfpl5 |
T |
A |
17: 28,801,962 (GRCm39) |
*220R |
probably null |
Het |
| Map4k2 |
C |
T |
19: 6,394,459 (GRCm39) |
T313I |
probably damaging |
Het |
| Matn2 |
A |
G |
15: 34,423,945 (GRCm39) |
D601G |
probably damaging |
Het |
| Mcur1 |
C |
T |
13: 43,705,147 (GRCm39) |
V170M |
possibly damaging |
Het |
| Mphosph10 |
T |
C |
7: 64,041,969 (GRCm39) |
|
probably benign |
Het |
| Nat8l |
G |
A |
5: 34,158,387 (GRCm39) |
A266T |
probably benign |
Het |
| Nckap5l |
G |
T |
15: 99,321,067 (GRCm39) |
P1238T |
probably damaging |
Het |
| Ngf |
A |
G |
3: 102,417,156 (GRCm39) |
|
probably benign |
Het |
| Ntng1 |
T |
A |
3: 109,842,184 (GRCm39) |
L196F |
probably damaging |
Het |
| Or2q1 |
A |
G |
6: 42,794,896 (GRCm39) |
I164V |
possibly damaging |
Het |
| Or2v2 |
A |
T |
11: 49,004,448 (GRCm39) |
V35D |
probably damaging |
Het |
| Pclo |
A |
T |
5: 14,725,045 (GRCm39) |
Y1301F |
unknown |
Het |
| Pclo |
A |
G |
5: 14,763,139 (GRCm39) |
T3871A |
unknown |
Het |
| Peli3 |
T |
C |
19: 4,982,594 (GRCm39) |
E357G |
probably damaging |
Het |
| Pkd1 |
T |
A |
17: 24,784,348 (GRCm39) |
|
probably null |
Het |
| Pla2g2c |
T |
G |
4: 138,461,645 (GRCm39) |
F38C |
probably damaging |
Het |
| Plekha2 |
T |
A |
8: 25,549,960 (GRCm39) |
T126S |
possibly damaging |
Het |
| Polr3f |
T |
A |
2: 144,376,001 (GRCm39) |
*142K |
probably null |
Het |
| Ppcs |
C |
T |
4: 119,276,343 (GRCm39) |
V81M |
probably benign |
Het |
| Prl7a1 |
A |
G |
13: 27,819,747 (GRCm39) |
I169T |
probably damaging |
Het |
| Rbm19 |
C |
A |
5: 120,271,799 (GRCm39) |
|
probably benign |
Het |
| Rdh7 |
T |
A |
10: 127,721,631 (GRCm39) |
Y215F |
probably benign |
Het |
| Rragd |
T |
G |
4: 32,995,072 (GRCm39) |
S62R |
probably benign |
Het |
| Rtel1 |
T |
C |
2: 180,997,728 (GRCm39) |
S1114P |
possibly damaging |
Het |
| Serpinb5 |
G |
T |
1: 106,800,069 (GRCm39) |
L86F |
probably damaging |
Het |
| Setbp1 |
A |
G |
18: 78,902,015 (GRCm39) |
S551P |
probably damaging |
Het |
| Setd6 |
T |
C |
8: 96,443,683 (GRCm39) |
|
probably benign |
Het |
| Slmap |
A |
C |
14: 26,183,507 (GRCm39) |
M292R |
probably damaging |
Het |
| Srrm4 |
T |
C |
5: 116,615,193 (GRCm39) |
D97G |
unknown |
Het |
| Stk-ps2 |
G |
A |
1: 46,068,125 (GRCm39) |
|
noncoding transcript |
Het |
| Syce1 |
A |
T |
7: 140,358,336 (GRCm39) |
M204K |
probably benign |
Het |
| Syk |
A |
G |
13: 52,765,242 (GRCm39) |
K123R |
probably benign |
Het |
| Tbc1d14 |
A |
T |
5: 36,729,175 (GRCm39) |
S64T |
probably damaging |
Het |
| Tmt1a3 |
A |
T |
15: 100,233,214 (GRCm39) |
D135V |
probably damaging |
Het |
| Traf3ip3 |
T |
C |
1: 192,867,137 (GRCm39) |
K295E |
probably damaging |
Het |
| Trp53bp2 |
T |
C |
1: 182,269,370 (GRCm39) |
|
probably null |
Het |
| Tsc2 |
T |
A |
17: 24,815,716 (GRCm39) |
|
probably null |
Het |
| Tspyl4 |
T |
A |
10: 34,173,734 (GRCm39) |
C75* |
probably null |
Het |
| Uqcc2 |
T |
C |
17: 27,344,133 (GRCm39) |
I52V |
probably benign |
Het |
| Vcp |
T |
A |
4: 42,983,486 (GRCm39) |
T525S |
probably damaging |
Het |
| Vmn2r18 |
A |
T |
5: 151,508,897 (GRCm39) |
|
probably null |
Het |
| Vmp1 |
A |
G |
11: 86,492,879 (GRCm39) |
V310A |
probably benign |
Het |
| Vps13d |
T |
A |
4: 144,795,735 (GRCm39) |
R3671S |
probably damaging |
Het |
| Wdr3 |
T |
C |
3: 100,053,861 (GRCm39) |
T544A |
possibly damaging |
Het |
| Zc3h14 |
C |
G |
12: 98,719,107 (GRCm39) |
D157E |
probably damaging |
Het |
| Zfp541 |
T |
A |
7: 15,824,307 (GRCm39) |
F1010I |
probably damaging |
Het |
| Zfp64 |
T |
C |
2: 168,768,032 (GRCm39) |
T527A |
probably benign |
Het |
| Zyx |
G |
T |
6: 42,333,421 (GRCm39) |
R449M |
probably damaging |
Het |
|
| Other mutations in Nckap5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00833:Nckap5
|
APN |
1 |
125,954,889 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00956:Nckap5
|
APN |
1 |
125,952,755 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01414:Nckap5
|
APN |
1 |
126,456,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Nckap5
|
APN |
1 |
125,950,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01508:Nckap5
|
APN |
1 |
125,953,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02071:Nckap5
|
APN |
1 |
125,909,305 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02129:Nckap5
|
APN |
1 |
125,955,432 (GRCm39) |
nonsense |
probably null |
|
|
IGL02821:Nckap5
|
APN |
1 |
125,955,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03174:Nckap5
|
APN |
1 |
125,909,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F5493:Nckap5
|
UTSW |
1 |
125,953,564 (GRCm39) |
missense |
probably benign |
|
|
G5030:Nckap5
|
UTSW |
1 |
125,953,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0033:Nckap5
|
UTSW |
1 |
125,867,979 (GRCm39) |
intron |
probably benign |
|
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0349:Nckap5
|
UTSW |
1 |
125,954,171 (GRCm39) |
missense |
probably benign |
|
|
R0482:Nckap5
|
UTSW |
1 |
125,954,102 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0508:Nckap5
|
UTSW |
1 |
125,909,121 (GRCm39) |
splice site |
probably null |
|
|
R0541:Nckap5
|
UTSW |
1 |
126,623,459 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0609:Nckap5
|
UTSW |
1 |
125,955,025 (GRCm39) |
nonsense |
probably null |
|
|
R0701:Nckap5
|
UTSW |
1 |
125,953,094 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0782:Nckap5
|
UTSW |
1 |
125,909,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1389:Nckap5
|
UTSW |
1 |
125,954,447 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1401:Nckap5
|
UTSW |
1 |
125,942,398 (GRCm39) |
splice site |
probably benign |
|
|
R1436:Nckap5
|
UTSW |
1 |
125,953,798 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1506:Nckap5
|
UTSW |
1 |
125,953,650 (GRCm39) |
nonsense |
probably null |
|
|
R1528:Nckap5
|
UTSW |
1 |
125,952,659 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1942:Nckap5
|
UTSW |
1 |
125,952,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Nckap5
|
UTSW |
1 |
125,942,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2055:Nckap5
|
UTSW |
1 |
125,954,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Nckap5
|
UTSW |
1 |
125,954,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2214:Nckap5
|
UTSW |
1 |
125,953,487 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2311:Nckap5
|
UTSW |
1 |
126,456,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2403:Nckap5
|
UTSW |
1 |
125,955,146 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2430:Nckap5
|
UTSW |
1 |
125,842,494 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Nckap5
|
UTSW |
1 |
125,954,274 (GRCm39) |
splice site |
probably null |
|
|
R3782:Nckap5
|
UTSW |
1 |
125,952,811 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4133:Nckap5
|
UTSW |
1 |
126,150,443 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4249:Nckap5
|
UTSW |
1 |
125,955,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4448:Nckap5
|
UTSW |
1 |
125,953,463 (GRCm39) |
nonsense |
probably null |
|
|
R4456:Nckap5
|
UTSW |
1 |
125,842,472 (GRCm39) |
unclassified |
probably benign |
|
|
R4682:Nckap5
|
UTSW |
1 |
126,030,279 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4907:Nckap5
|
UTSW |
1 |
125,953,889 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4908:Nckap5
|
UTSW |
1 |
125,955,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Nckap5
|
UTSW |
1 |
125,954,765 (GRCm39) |
nonsense |
probably null |
|
|
R4926:Nckap5
|
UTSW |
1 |
126,456,378 (GRCm39) |
intron |
probably benign |
|
|
R5032:Nckap5
|
UTSW |
1 |
125,904,786 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5133:Nckap5
|
UTSW |
1 |
125,961,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5197:Nckap5
|
UTSW |
1 |
126,150,410 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5238:Nckap5
|
UTSW |
1 |
125,955,461 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5257:Nckap5
|
UTSW |
1 |
125,952,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5277:Nckap5
|
UTSW |
1 |
125,954,277 (GRCm39) |
nonsense |
probably null |
|
|
R5512:Nckap5
|
UTSW |
1 |
125,955,481 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5700:Nckap5
|
UTSW |
1 |
125,904,662 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5789:Nckap5
|
UTSW |
1 |
125,955,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6029:Nckap5
|
UTSW |
1 |
125,953,523 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6249:Nckap5
|
UTSW |
1 |
125,952,667 (GRCm39) |
missense |
probably benign |
|
|
R6292:Nckap5
|
UTSW |
1 |
125,842,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6521:Nckap5
|
UTSW |
1 |
126,309,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Nckap5
|
UTSW |
1 |
125,950,931 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7017:Nckap5
|
UTSW |
1 |
126,030,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Nckap5
|
UTSW |
1 |
125,952,785 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7054:Nckap5
|
UTSW |
1 |
126,186,449 (GRCm39) |
splice site |
probably null |
|
|
R7204:Nckap5
|
UTSW |
1 |
125,954,104 (GRCm39) |
missense |
probably benign |
|
|
R7336:Nckap5
|
UTSW |
1 |
125,953,786 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7544:Nckap5
|
UTSW |
1 |
125,953,948 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7590:Nckap5
|
UTSW |
1 |
125,954,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7684:Nckap5
|
UTSW |
1 |
125,954,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7749:Nckap5
|
UTSW |
1 |
125,952,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7773:Nckap5
|
UTSW |
1 |
125,954,581 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7813:Nckap5
|
UTSW |
1 |
125,953,163 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7970:Nckap5
|
UTSW |
1 |
125,952,758 (GRCm39) |
nonsense |
probably null |
|
|
R7992:Nckap5
|
UTSW |
1 |
125,954,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8278:Nckap5
|
UTSW |
1 |
125,955,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8373:Nckap5
|
UTSW |
1 |
125,954,032 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8414:Nckap5
|
UTSW |
1 |
125,942,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8755:Nckap5
|
UTSW |
1 |
125,954,279 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9016:Nckap5
|
UTSW |
1 |
126,623,491 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
R9209:Nckap5
|
UTSW |
1 |
125,867,928 (GRCm39) |
missense |
unknown |
|
|
R9214:Nckap5
|
UTSW |
1 |
125,942,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9300:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
nonsense |
probably null |
|
|
R9464:Nckap5
|
UTSW |
1 |
125,952,494 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9572:Nckap5
|
UTSW |
1 |
125,955,454 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9721:Nckap5
|
UTSW |
1 |
125,955,017 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9748:Nckap5
|
UTSW |
1 |
125,953,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Nckap5
|
UTSW |
1 |
125,952,569 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1176:Nckap5
|
UTSW |
1 |
126,456,418 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Nckap5
|
UTSW |
1 |
126,150,396 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGCTGATGGAAATTTCATCCCTGG -3'
(R):5'- CCACACAGCCAAGTTCATGG -3'
Sequencing Primer
(F):5'- TGGTGACAGTGACGACTCCAG -3'
(R):5'- CAAGTTCATGGCCATGTGC -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation