Incidental Mutation 'R4817:Ccdc88a'
| ID |
369927 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc88a
|
| Ensembl Gene |
ENSMUSG00000032740 |
| Gene Name |
coiled coil domain containing 88A |
| Synonyms |
GIV, Girdin, D130005J21Rik, HkRP1, C330012F17Rik, C130096N06Rik, A430106J12Rik |
| MMRRC Submission |
042435-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4817 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
29323658-29460808 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 29410907 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Asparagine
at position 464
(K464N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000048978
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040182]
[ENSMUST00000155854]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000040182
AA Change: K464N
PolyPhen 2
Score 0.154 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000048978
Gene: ENSMUSG00000032740
AA Change: K464N
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HOOK
|
14 |
590 |
8.1e-36 |
PFAM |
|
low complexity region
|
614 |
625 |
N/A |
INTRINSIC |
|
Blast:BRLZ
|
665 |
719 |
6e-22 |
BLAST |
|
low complexity region
|
826 |
839 |
N/A |
INTRINSIC |
|
low complexity region
|
883 |
895 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
985 |
N/A |
INTRINSIC |
|
low complexity region
|
1093 |
1104 |
N/A |
INTRINSIC |
|
coiled coil region
|
1268 |
1385 |
N/A |
INTRINSIC |
|
low complexity region
|
1437 |
1444 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1576 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1609 |
1702 |
2.38e-6 |
PROSPERO |
|
internal_repeat_1
|
1708 |
1808 |
2.38e-6 |
PROSPERO |
|
low complexity region
|
1811 |
1824 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137227
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155854
|
| SMART Domains |
Protein: ENSMUSP00000115117
Gene: ENSMUSG00000032740
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
75 |
87 |
N/A |
INTRINSIC |
|
low complexity region
|
146 |
176 |
N/A |
INTRINSIC |
|
Blast:BRLZ
|
228 |
283 |
7e-6 |
BLAST |
|
low complexity region
|
284 |
295 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.2125 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
96% (108/112) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal weight loss, reduced angiogenesis, and premature death by P25. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acp2 |
T |
A |
2: 91,033,963 (GRCm39) |
D44E |
probably damaging |
Het |
| Acp5 |
T |
C |
9: 22,038,379 (GRCm39) |
I307M |
probably benign |
Het |
| Ahsa1 |
A |
G |
12: 87,319,940 (GRCm39) |
D245G |
possibly damaging |
Het |
| Ankrd40 |
A |
G |
11: 94,230,459 (GRCm39) |
K316E |
probably benign |
Het |
| Apol9b |
G |
A |
15: 77,620,088 (GRCm39) |
E295K |
possibly damaging |
Het |
| Aqp4 |
C |
A |
18: 15,532,815 (GRCm39) |
G93C |
probably damaging |
Het |
| Arhgap21 |
A |
G |
2: 20,854,967 (GRCm39) |
V1465A |
probably benign |
Het |
| Arhgap5 |
C |
T |
12: 52,565,992 (GRCm39) |
P988S |
possibly damaging |
Het |
| Asxl3 |
A |
C |
18: 22,658,511 (GRCm39) |
K2174Q |
probably damaging |
Het |
| Brf1 |
A |
T |
12: 112,935,921 (GRCm39) |
I250N |
probably damaging |
Het |
| Calm1 |
A |
G |
12: 100,169,832 (GRCm39) |
|
probably null |
Het |
| Ccdc33 |
C |
T |
9: 57,974,818 (GRCm39) |
V352M |
probably damaging |
Het |
| Cdadc1 |
AGACGGA |
AGA |
14: 59,806,440 (GRCm39) |
|
probably null |
Het |
| Cdc25b |
T |
A |
2: 131,035,223 (GRCm39) |
I327N |
probably damaging |
Het |
| Cenpf |
G |
A |
1: 189,414,566 (GRCm39) |
H184Y |
possibly damaging |
Het |
| Cimap1d |
G |
A |
10: 79,475,851 (GRCm39) |
P238S |
probably damaging |
Het |
| Col6a5 |
G |
A |
9: 105,811,497 (GRCm39) |
T674I |
unknown |
Het |
| Creg2 |
A |
T |
1: 39,662,358 (GRCm39) |
M258K |
probably damaging |
Het |
| Csf3r |
T |
A |
4: 125,931,449 (GRCm39) |
Y477* |
probably null |
Het |
| Cyp3a44 |
T |
A |
5: 145,740,565 (GRCm39) |
Y25F |
possibly damaging |
Het |
| Degs2 |
T |
A |
12: 108,655,325 (GRCm39) |
R283* |
probably null |
Het |
| Dido1 |
T |
C |
2: 180,303,209 (GRCm39) |
N1565S |
probably benign |
Het |
| Dnah6 |
A |
T |
6: 72,999,407 (GRCm39) |
M4008K |
probably benign |
Het |
| Dnmbp |
C |
A |
19: 43,838,411 (GRCm39) |
G1138V |
probably benign |
Het |
| Drosha |
A |
C |
15: 12,914,133 (GRCm39) |
H1136P |
probably damaging |
Het |
| Duox2 |
T |
G |
2: 122,126,996 (GRCm39) |
N173T |
probably damaging |
Het |
| Dync1li1 |
T |
G |
9: 114,534,162 (GRCm39) |
I87M |
probably benign |
Het |
| E2f8 |
A |
C |
7: 48,517,494 (GRCm39) |
S770A |
probably benign |
Het |
| Efemp1 |
A |
G |
11: 28,876,241 (GRCm39) |
T469A |
probably damaging |
Het |
| Eif3f |
A |
T |
7: 108,536,982 (GRCm39) |
T136S |
probably damaging |
Het |
| Enpp5 |
T |
C |
17: 44,391,871 (GRCm39) |
*46R |
probably null |
Het |
| Epb41l4b |
A |
G |
4: 57,103,428 (GRCm39) |
V136A |
probably damaging |
Het |
| Fam186a |
A |
C |
15: 99,831,419 (GRCm39) |
|
probably benign |
Het |
| Flt4 |
A |
G |
11: 49,516,242 (GRCm39) |
Y115C |
probably damaging |
Het |
| Gal |
T |
A |
19: 3,461,126 (GRCm39) |
|
probably null |
Het |
| Galnt3 |
C |
T |
2: 65,923,883 (GRCm39) |
V462I |
possibly damaging |
Het |
| Gas2l1 |
A |
G |
11: 5,011,429 (GRCm39) |
S467P |
possibly damaging |
Het |
| Gbx1 |
A |
G |
5: 24,731,204 (GRCm39) |
L204P |
probably damaging |
Het |
| Gle1 |
T |
A |
2: 29,826,223 (GRCm39) |
S101T |
probably benign |
Het |
| Gltpd2 |
A |
C |
11: 70,410,303 (GRCm39) |
Q87P |
probably damaging |
Het |
| Gm12789 |
T |
A |
4: 101,846,079 (GRCm39) |
D113E |
probably damaging |
Het |
| Grin3b |
G |
A |
10: 79,812,732 (GRCm39) |
G936R |
probably benign |
Het |
| Gtf3c2 |
C |
T |
5: 31,331,434 (GRCm39) |
|
probably null |
Het |
| Gvin3 |
T |
A |
7: 106,200,437 (GRCm39) |
|
noncoding transcript |
Het |
| Klhl28 |
T |
C |
12: 65,004,043 (GRCm39) |
T157A |
probably benign |
Het |
| Kmt2a |
A |
G |
9: 44,732,763 (GRCm39) |
|
probably benign |
Het |
| Lamp1 |
A |
G |
8: 13,222,541 (GRCm39) |
T242A |
probably benign |
Het |
| Lhfpl5 |
T |
G |
17: 28,795,300 (GRCm39) |
I109S |
possibly damaging |
Het |
| Lhfpl5 |
T |
A |
17: 28,801,962 (GRCm39) |
*220R |
probably null |
Het |
| Map4k2 |
C |
T |
19: 6,394,459 (GRCm39) |
T313I |
probably damaging |
Het |
| Matn2 |
A |
G |
15: 34,423,945 (GRCm39) |
D601G |
probably damaging |
Het |
| Mcur1 |
C |
T |
13: 43,705,147 (GRCm39) |
V170M |
possibly damaging |
Het |
| Mphosph10 |
T |
C |
7: 64,041,969 (GRCm39) |
|
probably benign |
Het |
| Nat8l |
G |
A |
5: 34,158,387 (GRCm39) |
A266T |
probably benign |
Het |
| Nckap5 |
G |
T |
1: 125,954,952 (GRCm39) |
D469E |
possibly damaging |
Het |
| Nckap5l |
G |
T |
15: 99,321,067 (GRCm39) |
P1238T |
probably damaging |
Het |
| Ngf |
A |
G |
3: 102,417,156 (GRCm39) |
|
probably benign |
Het |
| Ntng1 |
T |
A |
3: 109,842,184 (GRCm39) |
L196F |
probably damaging |
Het |
| Or2q1 |
A |
G |
6: 42,794,896 (GRCm39) |
I164V |
possibly damaging |
Het |
| Or2v2 |
A |
T |
11: 49,004,448 (GRCm39) |
V35D |
probably damaging |
Het |
| Pclo |
A |
T |
5: 14,725,045 (GRCm39) |
Y1301F |
unknown |
Het |
| Pclo |
A |
G |
5: 14,763,139 (GRCm39) |
T3871A |
unknown |
Het |
| Peli3 |
T |
C |
19: 4,982,594 (GRCm39) |
E357G |
probably damaging |
Het |
| Pkd1 |
T |
A |
17: 24,784,348 (GRCm39) |
|
probably null |
Het |
| Pla2g2c |
T |
G |
4: 138,461,645 (GRCm39) |
F38C |
probably damaging |
Het |
| Plekha2 |
T |
A |
8: 25,549,960 (GRCm39) |
T126S |
possibly damaging |
Het |
| Polr3f |
T |
A |
2: 144,376,001 (GRCm39) |
*142K |
probably null |
Het |
| Ppcs |
C |
T |
4: 119,276,343 (GRCm39) |
V81M |
probably benign |
Het |
| Prl7a1 |
A |
G |
13: 27,819,747 (GRCm39) |
I169T |
probably damaging |
Het |
| Rbm19 |
C |
A |
5: 120,271,799 (GRCm39) |
|
probably benign |
Het |
| Rdh7 |
T |
A |
10: 127,721,631 (GRCm39) |
Y215F |
probably benign |
Het |
| Rragd |
T |
G |
4: 32,995,072 (GRCm39) |
S62R |
probably benign |
Het |
| Rtel1 |
T |
C |
2: 180,997,728 (GRCm39) |
S1114P |
possibly damaging |
Het |
| Serpinb5 |
G |
T |
1: 106,800,069 (GRCm39) |
L86F |
probably damaging |
Het |
| Setbp1 |
A |
G |
18: 78,902,015 (GRCm39) |
S551P |
probably damaging |
Het |
| Setd6 |
T |
C |
8: 96,443,683 (GRCm39) |
|
probably benign |
Het |
| Slmap |
A |
C |
14: 26,183,507 (GRCm39) |
M292R |
probably damaging |
Het |
| Srrm4 |
T |
C |
5: 116,615,193 (GRCm39) |
D97G |
unknown |
Het |
| Stk-ps2 |
G |
A |
1: 46,068,125 (GRCm39) |
|
noncoding transcript |
Het |
| Syce1 |
A |
T |
7: 140,358,336 (GRCm39) |
M204K |
probably benign |
Het |
| Syk |
A |
G |
13: 52,765,242 (GRCm39) |
K123R |
probably benign |
Het |
| Tbc1d14 |
A |
T |
5: 36,729,175 (GRCm39) |
S64T |
probably damaging |
Het |
| Tmt1a3 |
A |
T |
15: 100,233,214 (GRCm39) |
D135V |
probably damaging |
Het |
| Traf3ip3 |
T |
C |
1: 192,867,137 (GRCm39) |
K295E |
probably damaging |
Het |
| Trp53bp2 |
T |
C |
1: 182,269,370 (GRCm39) |
|
probably null |
Het |
| Tsc2 |
T |
A |
17: 24,815,716 (GRCm39) |
|
probably null |
Het |
| Tspyl4 |
T |
A |
10: 34,173,734 (GRCm39) |
C75* |
probably null |
Het |
| Uqcc2 |
T |
C |
17: 27,344,133 (GRCm39) |
I52V |
probably benign |
Het |
| Vcp |
T |
A |
4: 42,983,486 (GRCm39) |
T525S |
probably damaging |
Het |
| Vmn2r18 |
A |
T |
5: 151,508,897 (GRCm39) |
|
probably null |
Het |
| Vmp1 |
A |
G |
11: 86,492,879 (GRCm39) |
V310A |
probably benign |
Het |
| Vps13d |
T |
A |
4: 144,795,735 (GRCm39) |
R3671S |
probably damaging |
Het |
| Wdr3 |
T |
C |
3: 100,053,861 (GRCm39) |
T544A |
possibly damaging |
Het |
| Zc3h14 |
C |
G |
12: 98,719,107 (GRCm39) |
D157E |
probably damaging |
Het |
| Zfp541 |
T |
A |
7: 15,824,307 (GRCm39) |
F1010I |
probably damaging |
Het |
| Zfp64 |
T |
C |
2: 168,768,032 (GRCm39) |
T527A |
probably benign |
Het |
| Zyx |
G |
T |
6: 42,333,421 (GRCm39) |
R449M |
probably damaging |
Het |
|
| Other mutations in Ccdc88a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00499:Ccdc88a
|
APN |
11 |
29,449,341 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL00577:Ccdc88a
|
APN |
11 |
29,374,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00766:Ccdc88a
|
APN |
11 |
29,451,046 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01384:Ccdc88a
|
APN |
11 |
29,453,915 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01541:Ccdc88a
|
APN |
11 |
29,350,283 (GRCm39) |
missense |
probably benign |
|
|
IGL01647:Ccdc88a
|
APN |
11 |
29,454,321 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02648:Ccdc88a
|
APN |
11 |
29,451,051 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02885:Ccdc88a
|
APN |
11 |
29,398,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03117:Ccdc88a
|
APN |
11 |
29,324,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03196:Ccdc88a
|
APN |
11 |
29,432,340 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
trailor
|
UTSW |
11 |
29,444,099 (GRCm39) |
splice site |
probably null |
|
|
R0011:Ccdc88a
|
UTSW |
11 |
29,324,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0011:Ccdc88a
|
UTSW |
11 |
29,324,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0083:Ccdc88a
|
UTSW |
11 |
29,453,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0108:Ccdc88a
|
UTSW |
11 |
29,453,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0326:Ccdc88a
|
UTSW |
11 |
29,411,021 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0565:Ccdc88a
|
UTSW |
11 |
29,411,042 (GRCm39) |
unclassified |
probably benign |
|
|
R0631:Ccdc88a
|
UTSW |
11 |
29,443,752 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0632:Ccdc88a
|
UTSW |
11 |
29,432,749 (GRCm39) |
unclassified |
probably benign |
|
|
R0762:Ccdc88a
|
UTSW |
11 |
29,413,112 (GRCm39) |
unclassified |
probably benign |
|
|
R0838:Ccdc88a
|
UTSW |
11 |
29,350,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0946:Ccdc88a
|
UTSW |
11 |
29,406,509 (GRCm39) |
missense |
probably benign |
|
|
R1192:Ccdc88a
|
UTSW |
11 |
29,454,049 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R1500:Ccdc88a
|
UTSW |
11 |
29,432,713 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1701:Ccdc88a
|
UTSW |
11 |
29,427,427 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R1826:Ccdc88a
|
UTSW |
11 |
29,439,637 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1902:Ccdc88a
|
UTSW |
11 |
29,411,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1903:Ccdc88a
|
UTSW |
11 |
29,411,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2021:Ccdc88a
|
UTSW |
11 |
29,453,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2023:Ccdc88a
|
UTSW |
11 |
29,413,546 (GRCm39) |
nonsense |
probably null |
|
|
R2284:Ccdc88a
|
UTSW |
11 |
29,444,099 (GRCm39) |
splice site |
probably null |
|
|
R3236:Ccdc88a
|
UTSW |
11 |
29,397,995 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R3409:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3410:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3411:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3430:Ccdc88a
|
UTSW |
11 |
29,398,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3620:Ccdc88a
|
UTSW |
11 |
29,380,227 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4204:Ccdc88a
|
UTSW |
11 |
29,413,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4515:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4518:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4519:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4693:Ccdc88a
|
UTSW |
11 |
29,432,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4705:Ccdc88a
|
UTSW |
11 |
29,372,586 (GRCm39) |
missense |
probably benign |
|
|
R4707:Ccdc88a
|
UTSW |
11 |
29,397,956 (GRCm39) |
missense |
probably benign |
|
|
R4732:Ccdc88a
|
UTSW |
11 |
29,435,906 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4733:Ccdc88a
|
UTSW |
11 |
29,435,906 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4734:Ccdc88a
|
UTSW |
11 |
29,432,720 (GRCm39) |
missense |
probably benign |
|
|
R4749:Ccdc88a
|
UTSW |
11 |
29,432,720 (GRCm39) |
missense |
probably benign |
|
|
R4828:Ccdc88a
|
UTSW |
11 |
29,413,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4979:Ccdc88a
|
UTSW |
11 |
29,432,133 (GRCm39) |
nonsense |
probably null |
|
|
R5288:Ccdc88a
|
UTSW |
11 |
29,448,416 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5373:Ccdc88a
|
UTSW |
11 |
29,413,409 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5374:Ccdc88a
|
UTSW |
11 |
29,413,409 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5401:Ccdc88a
|
UTSW |
11 |
29,413,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5586:Ccdc88a
|
UTSW |
11 |
29,453,484 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6660:Ccdc88a
|
UTSW |
11 |
29,432,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7116:Ccdc88a
|
UTSW |
11 |
29,454,051 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7353:Ccdc88a
|
UTSW |
11 |
29,413,368 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7538:Ccdc88a
|
UTSW |
11 |
29,413,370 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7663:Ccdc88a
|
UTSW |
11 |
29,448,614 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7769:Ccdc88a
|
UTSW |
11 |
29,432,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7798:Ccdc88a
|
UTSW |
11 |
29,427,348 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7810:Ccdc88a
|
UTSW |
11 |
29,435,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7826:Ccdc88a
|
UTSW |
11 |
29,453,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7956:Ccdc88a
|
UTSW |
11 |
29,413,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Ccdc88a
|
UTSW |
11 |
29,443,934 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8402:Ccdc88a
|
UTSW |
11 |
29,413,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8409:Ccdc88a
|
UTSW |
11 |
29,453,544 (GRCm39) |
missense |
probably benign |
|
|
R8555:Ccdc88a
|
UTSW |
11 |
29,380,169 (GRCm39) |
missense |
probably benign |
|
|
R8676:Ccdc88a
|
UTSW |
11 |
29,410,860 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8846:Ccdc88a
|
UTSW |
11 |
29,414,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8963:Ccdc88a
|
UTSW |
11 |
29,448,416 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8972:Ccdc88a
|
UTSW |
11 |
29,435,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9353:Ccdc88a
|
UTSW |
11 |
29,427,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Ccdc88a
|
UTSW |
11 |
29,453,922 (GRCm39) |
missense |
probably null |
0.55 |
|
R9385:Ccdc88a
|
UTSW |
11 |
29,405,422 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9509:Ccdc88a
|
UTSW |
11 |
29,414,143 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9610:Ccdc88a
|
UTSW |
11 |
29,427,316 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9611:Ccdc88a
|
UTSW |
11 |
29,427,316 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9664:Ccdc88a
|
UTSW |
11 |
29,405,484 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9720:Ccdc88a
|
UTSW |
11 |
29,413,813 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCCATAGAACTAGAACTCTATAGTCTC -3'
(R):5'- ATCTCAAGGCCACAAGGAGG -3'
Sequencing Primer
(F):5'- AGTTGTGTATGTTAGAAGCTCAAC -3'
(R):5'- AGGCAAGTGCTCTACCATTG -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation