Incidental Mutation 'R4820:Mmrn1'
| ID |
370123 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mmrn1
|
| Ensembl Gene |
ENSMUSG00000054641 |
| Gene Name |
multimerin 1 |
| Synonyms |
Emilin4, 4921530G03Rik |
| MMRRC Submission |
042436-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4820 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
60921301-60966362 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 60950027 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 326
(V326I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000145156
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000129603]
[ENSMUST00000204333]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129603
AA Change: V326I
PolyPhen 2
Score 0.044 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000119609
Gene: ENSMUSG00000054641
AA Change: V326I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
80 |
92 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
193 |
262 |
3.3e-12 |
PFAM |
|
coiled coil region
|
303 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
981 |
992 |
N/A |
INTRINSIC |
|
EGF
|
1026 |
1059 |
1.62e-5 |
SMART |
|
C1Q
|
1076 |
1210 |
6.74e-49 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000204333
AA Change: V326I
PolyPhen 2
Score 0.044 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000145156
Gene: ENSMUSG00000054641
AA Change: V326I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
80 |
92 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
193 |
262 |
7.7e-13 |
PFAM |
|
coiled coil region
|
303 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
981 |
992 |
N/A |
INTRINSIC |
|
EGF
|
1025 |
1058 |
1.62e-5 |
SMART |
|
C1Q
|
1075 |
1209 |
6.74e-49 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.3%
- 10x: 96.5%
- 20x: 92.9%
|
| Validation Efficiency |
96% (104/108) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930488N24Rik |
T |
C |
17: 14,326,481 (GRCm39) |
|
noncoding transcript |
Het |
| 5730455P16Rik |
A |
T |
11: 80,266,346 (GRCm39) |
S132T |
possibly damaging |
Het |
| Aadacl3 |
T |
A |
4: 144,184,527 (GRCm39) |
H77L |
probably damaging |
Het |
| Actr5 |
T |
A |
2: 158,467,426 (GRCm39) |
V122D |
probably damaging |
Het |
| Adamts7 |
A |
G |
9: 90,071,739 (GRCm39) |
D678G |
possibly damaging |
Het |
| Alpk1 |
T |
A |
3: 127,464,708 (GRCm39) |
D1190V |
probably benign |
Het |
| Apbb1ip |
A |
T |
2: 22,765,265 (GRCm39) |
N649Y |
unknown |
Het |
| Atp6v0a1 |
A |
G |
11: 100,933,776 (GRCm39) |
I522V |
probably benign |
Het |
| Brd10 |
T |
C |
19: 29,695,809 (GRCm39) |
N1228S |
possibly damaging |
Het |
| Cars1 |
T |
C |
7: 143,124,301 (GRCm39) |
D375G |
probably damaging |
Het |
| Catspere1 |
A |
T |
1: 177,687,441 (GRCm39) |
|
noncoding transcript |
Het |
| Ccdc87 |
A |
G |
19: 4,890,579 (GRCm39) |
D357G |
probably damaging |
Het |
| Cd101 |
A |
T |
3: 100,929,471 (GRCm39) |
S8T |
probably benign |
Het |
| Cfap65 |
C |
T |
1: 74,966,791 (GRCm39) |
A299T |
probably benign |
Het |
| Cic |
T |
C |
7: 24,971,157 (GRCm39) |
V296A |
possibly damaging |
Het |
| Col7a1 |
T |
A |
9: 108,797,675 (GRCm39) |
S1686T |
possibly damaging |
Het |
| Ctbp2 |
A |
C |
7: 132,615,423 (GRCm39) |
L504R |
probably damaging |
Het |
| Cttnbp2nl |
T |
C |
3: 104,918,640 (GRCm39) |
K67E |
probably benign |
Het |
| Cyp2c50 |
C |
T |
19: 40,102,024 (GRCm39) |
P480S |
probably damaging |
Het |
| Dcdc5 |
A |
C |
2: 106,166,420 (GRCm39) |
|
noncoding transcript |
Het |
| Defb2 |
G |
T |
8: 22,333,317 (GRCm39) |
E31* |
probably null |
Het |
| Dhrs1 |
T |
A |
14: 55,977,083 (GRCm39) |
N244I |
possibly damaging |
Het |
| Dop1b |
A |
G |
16: 93,589,978 (GRCm39) |
I134V |
probably benign |
Het |
| Eif1ad11 |
A |
T |
12: 87,994,158 (GRCm39) |
I129F |
unknown |
Het |
| Etl4 |
A |
G |
2: 20,811,496 (GRCm39) |
D1193G |
possibly damaging |
Het |
| Ezh1 |
A |
C |
11: 101,094,594 (GRCm39) |
S399R |
probably damaging |
Het |
| Fam161a |
T |
C |
11: 22,970,076 (GRCm39) |
S26P |
probably damaging |
Het |
| Fcgbp |
C |
A |
7: 27,813,383 (GRCm39) |
S2306Y |
probably damaging |
Het |
| Fras1 |
T |
C |
5: 96,876,512 (GRCm39) |
I2415T |
probably benign |
Het |
| Gas2l3 |
A |
G |
10: 89,252,907 (GRCm39) |
L246P |
probably damaging |
Het |
| Gdf15 |
C |
T |
8: 71,082,246 (GRCm39) |
V287M |
probably damaging |
Het |
| Gm7742 |
T |
C |
17: 21,420,235 (GRCm39) |
|
noncoding transcript |
Het |
| Grin2d |
T |
C |
7: 45,507,363 (GRCm39) |
D446G |
probably damaging |
Het |
| Hemk1 |
A |
G |
9: 107,205,385 (GRCm39) |
F107L |
probably benign |
Het |
| Hmgcr |
C |
T |
13: 96,796,700 (GRCm39) |
G197S |
probably damaging |
Het |
| Ift52 |
G |
A |
2: 162,873,108 (GRCm39) |
G207D |
probably benign |
Het |
| Il17re |
A |
G |
6: 113,442,816 (GRCm39) |
T275A |
probably benign |
Het |
| Iqcf3 |
T |
C |
9: 106,430,788 (GRCm39) |
|
probably benign |
Het |
| Kcna1 |
A |
G |
6: 126,619,099 (GRCm39) |
I407T |
probably damaging |
Het |
| Kcnrg |
T |
A |
14: 61,845,386 (GRCm39) |
M142K |
probably benign |
Het |
| Lhx9 |
C |
A |
1: 138,766,105 (GRCm39) |
V237L |
probably benign |
Het |
| Lipo3 |
A |
C |
19: 33,560,497 (GRCm39) |
I56S |
probably damaging |
Het |
| Loxhd1 |
C |
G |
18: 77,472,663 (GRCm39) |
P1060R |
probably damaging |
Het |
| Map2k4 |
A |
C |
11: 65,587,201 (GRCm39) |
|
probably benign |
Het |
| Methig1 |
A |
G |
15: 100,251,416 (GRCm39) |
K109R |
possibly damaging |
Het |
| Myo15a |
G |
A |
11: 60,367,741 (GRCm39) |
R167H |
probably damaging |
Het |
| Ncoa7 |
G |
A |
10: 30,524,472 (GRCm39) |
T142M |
probably damaging |
Het |
| Nfkb2 |
C |
A |
19: 46,296,493 (GRCm39) |
Q254K |
probably damaging |
Het |
| Nherf1 |
A |
G |
11: 115,070,918 (GRCm39) |
E290G |
probably benign |
Het |
| Nol6 |
G |
T |
4: 41,121,508 (GRCm39) |
P278Q |
probably damaging |
Het |
| Nptxr |
T |
A |
15: 79,677,027 (GRCm39) |
D285V |
probably damaging |
Het |
| Oosp3 |
T |
C |
19: 11,688,997 (GRCm39) |
W82R |
probably damaging |
Het |
| Or6b3 |
A |
T |
1: 92,438,812 (GRCm39) |
*313K |
probably null |
Het |
| Or6n1 |
A |
G |
1: 173,916,742 (GRCm39) |
I45M |
possibly damaging |
Het |
| Pa2g4 |
G |
T |
10: 128,395,199 (GRCm39) |
T322K |
probably damaging |
Het |
| Parp16 |
C |
A |
9: 65,145,175 (GRCm39) |
F291L |
probably damaging |
Het |
| Pdzd9 |
A |
T |
7: 120,267,619 (GRCm39) |
D65E |
probably damaging |
Het |
| Pgap3 |
A |
G |
11: 98,281,300 (GRCm39) |
W238R |
probably damaging |
Het |
| Pgf |
G |
A |
12: 85,218,538 (GRCm39) |
H67Y |
probably benign |
Het |
| Pik3cb |
T |
C |
9: 98,955,679 (GRCm39) |
T413A |
probably benign |
Het |
| Plcxd2 |
A |
T |
16: 45,800,700 (GRCm39) |
C175S |
probably benign |
Het |
| Pou2f1 |
A |
T |
1: 165,719,517 (GRCm39) |
|
probably benign |
Het |
| Ppfia1 |
T |
G |
7: 144,052,106 (GRCm39) |
N846T |
probably benign |
Het |
| Ppid |
T |
A |
3: 79,502,504 (GRCm39) |
|
probably null |
Het |
| Prkcq |
G |
A |
2: 11,231,797 (GRCm39) |
|
probably null |
Het |
| Ptgds |
T |
C |
2: 25,359,058 (GRCm39) |
K66E |
probably benign |
Het |
| Ptpmt1 |
A |
G |
2: 90,748,283 (GRCm39) |
|
noncoding transcript |
Het |
| Rab3il1 |
G |
A |
19: 10,004,034 (GRCm39) |
G51D |
probably benign |
Het |
| Rdx |
T |
C |
9: 51,974,891 (GRCm39) |
V9A |
probably damaging |
Het |
| Rpl7l1 |
T |
C |
17: 47,089,014 (GRCm39) |
N239S |
probably benign |
Het |
| Rrbp1 |
C |
A |
2: 143,806,685 (GRCm39) |
A978S |
possibly damaging |
Het |
| Rsf1 |
GCGGCGGCG |
GCGGCGGCGCCGGCGGCG |
7: 97,229,126 (GRCm39) |
|
probably benign |
Het |
| Scn3a |
A |
T |
2: 65,291,622 (GRCm39) |
I1708N |
probably damaging |
Het |
| Serinc1 |
A |
G |
10: 57,401,466 (GRCm39) |
I109T |
possibly damaging |
Het |
| Shroom1 |
G |
A |
11: 53,355,966 (GRCm39) |
V339I |
probably benign |
Het |
| Slc30a8 |
T |
A |
15: 52,169,880 (GRCm39) |
C36S |
probably benign |
Het |
| Slco1b2 |
A |
G |
6: 141,631,158 (GRCm39) |
I597M |
probably benign |
Het |
| Snx27 |
A |
G |
3: 94,427,518 (GRCm39) |
F228S |
probably damaging |
Het |
| Spata31f1a |
T |
A |
4: 42,851,815 (GRCm39) |
I114F |
probably damaging |
Het |
| Speer4e2 |
G |
T |
5: 15,026,225 (GRCm39) |
T144K |
probably benign |
Het |
| Stim1 |
T |
A |
7: 102,064,571 (GRCm39) |
F214I |
probably damaging |
Het |
| Svep1 |
T |
C |
4: 58,082,664 (GRCm39) |
T1987A |
probably benign |
Het |
| Tamm41 |
A |
G |
6: 115,002,378 (GRCm39) |
I18T |
possibly damaging |
Het |
| Tmem150b |
T |
A |
7: 4,726,871 (GRCm39) |
D79V |
probably damaging |
Het |
| Tmem167 |
T |
A |
13: 90,252,548 (GRCm39) |
I68N |
probably benign |
Het |
| Traf3 |
A |
G |
12: 111,227,204 (GRCm39) |
E339G |
possibly damaging |
Het |
| Tspan12 |
G |
A |
6: 21,795,660 (GRCm39) |
P177S |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,783,562 (GRCm39) |
I810T |
probably benign |
Het |
| Ulk1 |
T |
C |
5: 110,939,996 (GRCm39) |
T407A |
probably benign |
Het |
| Uroc1 |
G |
A |
6: 90,334,600 (GRCm39) |
|
probably null |
Het |
| Vmn2r-ps69 |
T |
C |
7: 84,959,584 (GRCm39) |
|
noncoding transcript |
Het |
| Wdr59 |
T |
C |
8: 112,207,446 (GRCm39) |
N476S |
probably benign |
Het |
| Zfp472 |
A |
G |
17: 33,196,416 (GRCm39) |
M164V |
probably benign |
Het |
| Zfp608 |
T |
C |
18: 55,120,756 (GRCm39) |
N277S |
probably benign |
Het |
| Zfp831 |
T |
C |
2: 174,547,097 (GRCm39) |
C1427R |
possibly damaging |
Het |
|
| Other mutations in Mmrn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00640:Mmrn1
|
APN |
6 |
60,954,497 (GRCm39) |
missense |
probably benign |
|
|
IGL00742:Mmrn1
|
APN |
6 |
60,935,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00917:Mmrn1
|
APN |
6 |
60,952,894 (GRCm39) |
nonsense |
probably null |
|
|
IGL01121:Mmrn1
|
APN |
6 |
60,952,928 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01393:Mmrn1
|
APN |
6 |
60,937,692 (GRCm39) |
splice site |
probably benign |
|
|
IGL01697:Mmrn1
|
APN |
6 |
60,953,477 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01737:Mmrn1
|
APN |
6 |
60,954,145 (GRCm39) |
missense |
probably benign |
|
|
IGL01944:Mmrn1
|
APN |
6 |
60,948,167 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01987:Mmrn1
|
APN |
6 |
60,921,557 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02005:Mmrn1
|
APN |
6 |
60,937,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02190:Mmrn1
|
APN |
6 |
60,964,177 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02335:Mmrn1
|
APN |
6 |
60,954,131 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL02421:Mmrn1
|
APN |
6 |
60,921,806 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02530:Mmrn1
|
APN |
6 |
60,935,160 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02709:Mmrn1
|
APN |
6 |
60,950,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03139:Mmrn1
|
APN |
6 |
60,953,324 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03228:Mmrn1
|
APN |
6 |
60,921,876 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03272:Mmrn1
|
APN |
6 |
60,965,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03410:Mmrn1
|
APN |
6 |
60,952,819 (GRCm39) |
missense |
probably benign |
0.36 |
|
H8562:Mmrn1
|
UTSW |
6 |
60,935,164 (GRCm39) |
missense |
probably damaging |
0.98 |
|
K2124:Mmrn1
|
UTSW |
6 |
60,953,017 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0145:Mmrn1
|
UTSW |
6 |
60,949,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0164:Mmrn1
|
UTSW |
6 |
60,952,799 (GRCm39) |
splice site |
probably benign |
|
|
R0352:Mmrn1
|
UTSW |
6 |
60,921,955 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0400:Mmrn1
|
UTSW |
6 |
60,954,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0538:Mmrn1
|
UTSW |
6 |
60,953,453 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0907:Mmrn1
|
UTSW |
6 |
60,950,103 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1117:Mmrn1
|
UTSW |
6 |
60,953,309 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1383:Mmrn1
|
UTSW |
6 |
60,953,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mmrn1
|
UTSW |
6 |
60,922,102 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1591:Mmrn1
|
UTSW |
6 |
60,921,755 (GRCm39) |
nonsense |
probably null |
|
|
R1599:Mmrn1
|
UTSW |
6 |
60,922,021 (GRCm39) |
missense |
probably benign |
|
|
R1733:Mmrn1
|
UTSW |
6 |
60,954,085 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2005:Mmrn1
|
UTSW |
6 |
60,953,068 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2056:Mmrn1
|
UTSW |
6 |
60,921,789 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2144:Mmrn1
|
UTSW |
6 |
60,922,059 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R2299:Mmrn1
|
UTSW |
6 |
60,953,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3836:Mmrn1
|
UTSW |
6 |
60,921,831 (GRCm39) |
missense |
probably benign |
|
|
R3837:Mmrn1
|
UTSW |
6 |
60,921,831 (GRCm39) |
missense |
probably benign |
|
|
R4206:Mmrn1
|
UTSW |
6 |
60,935,164 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4414:Mmrn1
|
UTSW |
6 |
60,921,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4590:Mmrn1
|
UTSW |
6 |
60,937,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Mmrn1
|
UTSW |
6 |
60,965,457 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4880:Mmrn1
|
UTSW |
6 |
60,953,423 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5166:Mmrn1
|
UTSW |
6 |
60,953,474 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5324:Mmrn1
|
UTSW |
6 |
60,953,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5887:Mmrn1
|
UTSW |
6 |
60,964,058 (GRCm39) |
missense |
probably benign |
|
|
R5917:Mmrn1
|
UTSW |
6 |
60,950,134 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6108:Mmrn1
|
UTSW |
6 |
60,952,960 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6539:Mmrn1
|
UTSW |
6 |
60,964,168 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6996:Mmrn1
|
UTSW |
6 |
60,954,367 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7064:Mmrn1
|
UTSW |
6 |
60,965,524 (GRCm39) |
nonsense |
probably null |
|
|
R7073:Mmrn1
|
UTSW |
6 |
60,965,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7213:Mmrn1
|
UTSW |
6 |
60,921,527 (GRCm39) |
start gained |
probably benign |
|
|
R7256:Mmrn1
|
UTSW |
6 |
60,953,098 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7324:Mmrn1
|
UTSW |
6 |
60,921,917 (GRCm39) |
nonsense |
probably null |
|
|
R7350:Mmrn1
|
UTSW |
6 |
60,953,320 (GRCm39) |
nonsense |
probably null |
|
|
R7388:Mmrn1
|
UTSW |
6 |
60,953,236 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7652:Mmrn1
|
UTSW |
6 |
60,954,490 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7664:Mmrn1
|
UTSW |
6 |
60,953,689 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7810:Mmrn1
|
UTSW |
6 |
60,953,309 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7832:Mmrn1
|
UTSW |
6 |
60,964,044 (GRCm39) |
splice site |
probably null |
|
|
R7979:Mmrn1
|
UTSW |
6 |
60,952,961 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8071:Mmrn1
|
UTSW |
6 |
60,921,508 (GRCm39) |
start gained |
probably benign |
|
|
R8130:Mmrn1
|
UTSW |
6 |
60,937,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8277:Mmrn1
|
UTSW |
6 |
60,954,220 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8353:Mmrn1
|
UTSW |
6 |
60,965,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8453:Mmrn1
|
UTSW |
6 |
60,965,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8472:Mmrn1
|
UTSW |
6 |
60,965,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8758:Mmrn1
|
UTSW |
6 |
60,964,193 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8803:Mmrn1
|
UTSW |
6 |
60,965,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8879:Mmrn1
|
UTSW |
6 |
60,953,513 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8907:Mmrn1
|
UTSW |
6 |
60,953,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8983:Mmrn1
|
UTSW |
6 |
60,953,042 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9200:Mmrn1
|
UTSW |
6 |
60,953,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9287:Mmrn1
|
UTSW |
6 |
60,952,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9387:Mmrn1
|
UTSW |
6 |
60,935,176 (GRCm39) |
nonsense |
probably null |
|
|
R9612:Mmrn1
|
UTSW |
6 |
60,953,408 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9674:Mmrn1
|
UTSW |
6 |
60,948,072 (GRCm39) |
nonsense |
probably null |
|
|
X0026:Mmrn1
|
UTSW |
6 |
60,952,997 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1176:Mmrn1
|
UTSW |
6 |
60,922,018 (GRCm39) |
missense |
probably benign |
0.37 |
|
Z1177:Mmrn1
|
UTSW |
6 |
60,964,082 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATGTTGCCACTCACCTGTAAC -3'
(R):5'- CAAATGACAGGAGACAATGTCACTG -3'
Sequencing Primer
(F):5'- GTTGAATGGTCCCAACTC -3'
(R):5'- AGACAATGTCACTGAGGAATTTG -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation