Mutagenetix > Incidental Mutation

Incidental Mutation 'R4801:Vps13c'

370402

Institutional Source

Beutler Lab

Gene Symbol

Vps13c

Ensembl Gene

ENSMUSG00000035284

Gene Name

vacuolar protein sorting 13C

Synonyms

C230055H22Rik

MMRRC Submission

042423-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4801 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

67840396-67995638 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 67964282 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Leucine at position 3244 (F3244L)

Ref Sequence

ENSEMBL: ENSMUSP00000077040 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000077879]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000077879
AA Change: F3244L

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000077040
Gene: ENSMUSG00000035284
AA Change: F3244L

Domain	Start	End	E-Value	Type
Pfam:Chorein_N	3	117	1.3e-39	PFAM
low complexity region	151	165	N/A	INTRINSIC
Pfam:VPS13	182	414	7.9e-70	PFAM
coiled coil region	422	443	N/A	INTRINSIC
low complexity region	479	490	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	611	832	7.8e-71	PFAM
low complexity region	867	885	N/A	INTRINSIC
low complexity region	1020	1036	N/A	INTRINSIC
low complexity region	1112	1123	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	1172	1369	2.1e-14	PFAM
low complexity region	1552	1573	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	1685	1883	2.8e-13	PFAM
Blast:INB	2128	2403	2e-48	BLAST
Pfam:SHR-BD	2759	3013	9.9e-32	PFAM
Pfam:VPS13_C	3317	3495	5.7e-65	PFAM
Pfam:ATG_C	3498	3588	7.9e-12	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000213168
AA Change: F377L

Meta Mutation Damage Score

0.2739

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.1%
20x: 94.8%

Validation Efficiency

99% (88/89)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the vacuolar protein sorting-associated 13 gene family. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]

Allele List at MGI

All alleles(13) : Targeted, other(2) Gene trapped(11)

Other mutations in this stock

Total: 164 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310057J18Rik	A	G	10: 28,983,926 (GRCm38)		probably null	Het
Aadacl3	A	G	4: 144,456,232 (GRCm38)	I222T	probably damaging	Het
Abca13	G	T	11: 9,522,341 (GRCm38)	G4249V	possibly damaging	Het
Abcb10	A	G	8: 123,966,527 (GRCm38)	V346A	probably benign	Het
Abcc2	A	T	19: 43,819,361 (GRCm38)	I814F	probably damaging	Het
AF366264	T	A	8: 13,836,970 (GRCm38)	I374F	possibly damaging	Het
Alkbh2	C	T	5: 114,124,226 (GRCm38)	E148K	probably damaging	Het
Ankrd28	A	C	14: 31,736,830 (GRCm38)	D335E	probably damaging	Het
Ankrd44	T	C	1: 54,762,316 (GRCm38)	H284R	probably damaging	Het
Arfgef3	G	T	10: 18,591,906 (GRCm38)	Q1849K	probably benign	Het
Atp2c2	T	C	8: 119,747,687 (GRCm38)	M490T	probably damaging	Het
Bach1	T	A	16: 87,722,452 (GRCm38)	D543E	probably damaging	Het
Bahcc1	G	A	11: 120,282,225 (GRCm38)	V1558I	probably benign	Het
Bbs5	T	A	2: 69,655,614 (GRCm38)	W168R	probably damaging	Het
Bcar3	A	T	3: 122,529,594 (GRCm38)	D766V	probably benign	Het
C1ra	A	G	6: 124,513,768 (GRCm38)	D40G	probably benign	Het
Ccdc138	G	A	10: 58,573,643 (GRCm38)	C598Y	probably damaging	Het
Cd200r3	T	A	16: 44,957,825 (GRCm38)	N197K	possibly damaging	Het
Cenpf	T	A	1: 189,651,220 (GRCm38)	E2634D	probably damaging	Het
Cisd2	T	C	3: 135,411,141 (GRCm38)	K63R	probably damaging	Het
Clca3a2	A	T	3: 144,807,351 (GRCm38)	S478T	possibly damaging	Het
Clptm1l	T	C	13: 73,607,862 (GRCm38)	M199T	possibly damaging	Het
Cntnap4	T	A	8: 112,773,590 (GRCm38)	S505T	possibly damaging	Het
Cr2	C	T	1: 195,163,311 (GRCm38)	G112D	probably damaging	Het
Crb2	T	A	2: 37,793,756 (GRCm38)	I1090N	probably benign	Het
Csmd3	G	T	15: 47,621,292 (GRCm38)	P3057Q	probably damaging	Het
Ctso	G	A	3: 81,954,240 (GRCm38)	V307I	probably damaging	Het
Cyp3a41b	T	A	5: 145,573,651 (GRCm38)	T138S	probably benign	Het
Dctn3	G	T	4: 41,719,904 (GRCm38)	Y67*	probably null	Het
Dennd4c	C	A	4: 86,819,884 (GRCm38)	Y918*	probably null	Het
Dlg5	C	T	14: 24,154,689 (GRCm38)	G1262D	probably damaging	Het
Dnaaf1	G	A	8: 119,577,361 (GRCm38)	G46D	probably benign	Het
Dnah6	A	G	6: 73,089,698 (GRCm38)	V2563A	probably damaging	Het
Dnajc13	A	G	9: 104,175,727 (GRCm38)	Y1679H	probably benign	Het
Eif2ak3	T	C	6: 70,887,893 (GRCm38)	Y578H	probably benign	Het
Endod1	C	T	9: 14,357,023 (GRCm38)	V389M	probably benign	Het
Ephb4	T	C	5: 137,365,506 (GRCm38)	L582P	probably damaging	Het
Eps15	T	C	4: 109,324,217 (GRCm38)	L316S	possibly damaging	Het
Erbb4	G	T	1: 68,330,246 (GRCm38)	T412K	probably damaging	Het
Fam117a	T	A	11: 95,364,070 (GRCm38)	F90I	probably damaging	Het
Fam187b	T	G	7: 30,977,090 (GRCm38)	V8G	possibly damaging	Het
Fam84b	C	A	15: 60,823,944 (GRCm38)		probably benign	Het
Far1	T	A	7: 113,539,453 (GRCm38)	I59N	possibly damaging	Het
Fbxo34	T	A	14: 47,530,869 (GRCm38)	L562Q	probably damaging	Het
Frem1	T	A	4: 82,916,628 (GRCm38)		probably benign	Het
Gfra3	G	T	18: 34,720,192 (GRCm38)	P10Q	probably damaging	Het
Gm10698	A	G	9: 33,728,772 (GRCm38)		noncoding transcript	Het
Gm11487	C	T	4: 73,401,267 (GRCm38)	W80*	probably null	Het
Gm19965	T	A	1: 116,821,896 (GRCm38)	Y436N	probably benign	Het
Gm21818	T	A	13: 120,173,222 (GRCm38)	S13R	probably benign	Het
Gm5767	A	G	16: 8,683,345 (GRCm38)	T22A	unknown	Het
Gm5799	A	T	14: 43,544,548 (GRCm38)	H59L	probably damaging	Het
Gmppb	T	A	9: 108,050,217 (GRCm38)	V121E	probably benign	Het
Ighv7-4	G	C	12: 114,223,279 (GRCm38)		probably benign	Het
Ipo4	A	G	14: 55,631,214 (GRCm38)	S446P	probably damaging	Het
Itpr2	T	C	6: 146,371,331 (GRCm38)	T855A	probably damaging	Het
Jaml	T	C	9: 45,101,064 (GRCm38)	I283T	possibly damaging	Het
Kcnn2	T	C	18: 45,685,267 (GRCm38)		probably benign	Het
Klhl32	T	C	4: 24,649,698 (GRCm38)	Y399C	possibly damaging	Het
Lrriq1	G	A	10: 103,221,318 (GRCm38)	T207I	probably benign	Het
Lrriq3	A	T	3: 155,187,970 (GRCm38)	H436L	probably benign	Het
Mad2l1bp	T	C	17: 46,148,263 (GRCm38)	K114E	possibly damaging	Het
Mamstr	T	C	7: 45,642,418 (GRCm38)	V64A	possibly damaging	Het
Map4	T	A	9: 110,035,257 (GRCm38)	S517T	probably benign	Het
Matn1	A	T	4: 130,950,025 (GRCm38)	I182F	possibly damaging	Het
Mcm3	A	G	1: 20,810,156 (GRCm38)	I484T	probably damaging	Het
Med13	T	A	11: 86,278,773 (GRCm38)	I1922F	probably damaging	Het
Metap2	A	G	10: 93,868,895 (GRCm38)	V137A	probably damaging	Het
Mex3d	A	G	10: 80,386,954 (GRCm38)	V156A	possibly damaging	Het
Mfsd6	G	A	1: 52,709,596 (GRCm38)	P37S	probably benign	Het
Mkl1	T	C	15: 81,104,799 (GRCm38)	E7G	probably benign	Het
Mrgprx1	A	C	7: 48,021,211 (GRCm38)	S263A	possibly damaging	Het
Msl1	C	T	11: 98,803,969 (GRCm38)	R505*	probably null	Het
Mta2	T	C	19: 8,945,851 (GRCm38)	S96P	probably damaging	Het
Mtr	A	T	13: 12,195,251 (GRCm38)	N986K	probably benign	Het
Mut	A	G	17: 40,937,351 (GRCm38)	T90A	probably benign	Het
Mutyh	C	T	4: 116,817,029 (GRCm38)	T259I	probably benign	Het
Myof	T	C	19: 37,945,738 (GRCm38)	T908A	probably benign	Het
Nav2	A	T	7: 49,545,852 (GRCm38)	D992V	possibly damaging	Het
Neb	T	C	2: 52,200,703 (GRCm38)	T1352A	possibly damaging	Het
Nfix	CAAAAA	CAAAA	8: 84,716,247 (GRCm38)		probably null	Het
Nudt6	G	A	3: 37,405,354 (GRCm38)	R161C	probably benign	Het
Olfr1122	T	A	2: 87,388,209 (GRCm38)	V168E	probably benign	Het
Olfr1173	T	A	2: 88,274,879 (GRCm38)	M57L	probably damaging	Het
Olfr125	T	C	17: 37,835,349 (GRCm38)	Y117H	probably damaging	Het
Olfr1276	T	A	2: 111,257,152 (GRCm38)	F12L	probably damaging	Het
Olfr1411	T	A	1: 92,596,998 (GRCm38)	C160S	probably benign	Het
Olfr154	T	A	2: 85,664,278 (GRCm38)	D52V	probably damaging	Het
Olfr23	T	A	11: 73,940,870 (GRCm38)	I208K	possibly damaging	Het
Olfr319	T	C	11: 58,701,791 (GRCm38)	V30A	probably benign	Het
Olfr456	A	T	6: 42,486,679 (GRCm38)	N171K	probably benign	Het
Olfr744	A	G	14: 50,619,022 (GRCm38)	T267A	probably benign	Het
Olfr959	T	G	9: 39,572,858 (GRCm38)	M134L	probably benign	Het
Olr1	A	G	6: 129,488,090 (GRCm38)	F141S	possibly damaging	Het
Oprl1	G	T	2: 181,719,253 (GRCm38)	M340I	probably benign	Het
Otogl	A	C	10: 107,901,336 (GRCm38)	C72W	probably damaging	Het
Pcdha11	T	A	18: 37,005,465 (GRCm38)	I49N	probably damaging	Het
Pcdha4	T	A	18: 36,953,955 (GRCm38)	L397*	probably null	Het
Pcdhb14	A	G	18: 37,448,278 (GRCm38)	S146G	probably benign	Het
Pclo	T	A	5: 14,675,815 (GRCm38)	H1562Q	unknown	Het
Pcsk9	T	C	4: 106,447,569 (GRCm38)	E434G	probably benign	Het
Phc2	A	G	4: 128,751,598 (GRCm38)	K833E	probably damaging	Het
Pja2	A	T	17: 64,292,862 (GRCm38)	S480R	probably damaging	Het
Pkd1	G	A	17: 24,578,096 (GRCm38)	G2493D	probably damaging	Het
Plk5	G	A	10: 80,359,304 (GRCm38)	V179M	possibly damaging	Het
Polr1a	G	A	6: 71,976,070 (GRCm38)	V1541I	probably benign	Het
Ppard	C	G	17: 28,286,374 (GRCm38)	R12G	unknown	Het
Ppp1r14a	A	G	7: 29,291,526 (GRCm38)	D73G	probably damaging	Het
Psd3	C	T	8: 68,121,148 (GRCm38)	R127H	probably benign	Het
Pten	G	T	19: 32,758,503 (GRCm38)	G20V	possibly damaging	Het
Ptprg	T	C	14: 11,554,233 (GRCm38)		probably benign	Het
Rad54l	T	C	4: 116,122,924 (GRCm38)	D21G	probably null	Het
Rgs14	T	C	13: 55,380,957 (GRCm38)	Y304H	probably damaging	Het
Rgs9	T	C	11: 109,240,868 (GRCm38)	K346R	probably damaging	Het
Rnf169	C	G	7: 99,926,446 (GRCm38)	G314A	probably damaging	Het
Rpgrip1l	T	A	8: 91,270,177 (GRCm38)	T692S	probably damaging	Het
Rtf1	T	C	2: 119,675,228 (GRCm38)	V54A	possibly damaging	Het
Rtn4	T	C	11: 29,708,660 (GRCm38)	V938A	probably benign	Het
Ryr2	T	C	13: 11,708,227 (GRCm38)	T2509A	probably damaging	Het
Ryr2	T	A	13: 11,687,932 (GRCm38)	D2890V	probably damaging	Het
Scel	A	C	14: 103,583,100 (GRCm38)	T348P	probably benign	Het
Scgb1b2	G	T	7: 31,291,573 (GRCm38)	L37I	possibly damaging	Het
Sdf4	A	G	4: 156,000,721 (GRCm38)	H171R	possibly damaging	Het
Sec31a	A	G	5: 100,393,363 (GRCm38)	V295A	probably damaging	Het
Setx	T	A	2: 29,146,373 (GRCm38)	S957T	probably benign	Het
Shroom3	G	T	5: 92,943,086 (GRCm38)	V1151F	probably damaging	Het
Six5	A	G	7: 19,096,969 (GRCm38)	N507S	probably benign	Het
Slc12a7	T	C	13: 73,763,892 (GRCm38)		probably null	Het
Slc1a7	T	A	4: 107,993,040 (GRCm38)	V116E	probably damaging	Het
Slc22a1	A	G	17: 12,675,535 (GRCm38)	L42P	probably damaging	Het
Slc25a31	A	T	3: 40,721,545 (GRCm38)	I174F	probably damaging	Het
Slc31a2	A	T	4: 62,292,632 (GRCm38)	M3L	probably damaging	Het
Slco1a4	T	A	6: 141,845,497 (GRCm38)		probably benign	Het
Smcr8	C	T	11: 60,778,610 (GRCm38)		probably null	Het
Smg5	G	T	3: 88,355,692 (GRCm38)	E801*	probably null	Het
Smgc	C	A	15: 91,854,616 (GRCm38)	H492Q	probably benign	Het
Smyd4	G	T	11: 75,403,184 (GRCm38)	G694V	probably damaging	Het
Sorcs3	A	G	19: 48,398,744 (GRCm38)	T223A	possibly damaging	Het
Stab1	G	T	14: 31,141,371 (GRCm38)	C2119*	probably null	Het
Taar9	A	G	10: 24,108,843 (GRCm38)	I231T	probably damaging	Het
Tacr2	A	G	10: 62,261,548 (GRCm38)	Y269C	probably damaging	Het
Taf3	T	G	2: 9,951,123 (GRCm38)	K744N	possibly damaging	Het
Tenm4	T	A	7: 96,906,245 (GRCm38)	V2682E	probably damaging	Het
Tet1	A	C	10: 62,822,663 (GRCm38)	L1468R	probably damaging	Het
Tgds	T	C	14: 118,117,033 (GRCm38)		probably benign	Het
Tgfb2	A	T	1: 186,628,913 (GRCm38)	Y380*	probably null	Het
Tgm5	T	G	2: 121,052,472 (GRCm38)	K435Q	probably damaging	Het
Themis	A	G	10: 28,761,511 (GRCm38)	T204A	probably benign	Het
Tm4sf1	T	C	3: 57,294,679 (GRCm38)	Y37C	probably damaging	Het
Tnn	T	C	1: 160,145,033 (GRCm38)	N333S	possibly damaging	Het
Tppp2	A	G	14: 51,919,348 (GRCm38)	N61D	probably benign	Het
Treml2	A	G	17: 48,309,159 (GRCm38)	T276A	probably benign	Het
Trit1	T	C	4: 123,016,638 (GRCm38)	V10A	probably benign	Het
Uba1y	T	G	Y: 825,890 (GRCm38)		probably null	Het
Uqcc1	T	C	2: 155,858,106 (GRCm38)		probably benign	Het
Vcam1	C	G	3: 116,115,935 (GRCm38)	G581A	probably damaging	Het
Vmn1r16	G	A	6: 57,323,190 (GRCm38)	T149I	probably benign	Het
Vmn1r209	T	C	13: 22,805,656 (GRCm38)	D288G	probably damaging	Het
Vmn1r78	T	A	7: 12,152,964 (GRCm38)	Y167*	probably null	Het
Vmn2r103	T	A	17: 19,795,076 (GRCm38)	S493T	probably benign	Het
Vmn2r105	T	A	17: 20,227,294 (GRCm38)	M423L	probably benign	Het
Zfp119b	A	T	17: 55,939,642 (GRCm38)	D149E	probably damaging	Het
Zfp345	T	C	2: 150,473,308 (GRCm38)	Y103C	possibly damaging	Het
Zmym6	C	T	4: 127,123,216 (GRCm38)	T930I	probably benign	Het

Other mutations in Vps13c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00159:Vps13c	APN	9	67,945,999 (GRCm38)	missense	probably benign	0.20
IGL00336:Vps13c	APN	9	67,945,942 (GRCm38)	missense	probably benign	0.01
IGL00418:Vps13c	APN	9	67,876,262 (GRCm38)	missense	probably damaging	1.00
IGL00481:Vps13c	APN	9	67,860,865 (GRCm38)	missense	probably damaging	1.00
IGL00491:Vps13c	APN	9	67,893,136 (GRCm38)	missense	probably damaging	1.00
IGL00558:Vps13c	APN	9	67,937,857 (GRCm38)	missense	possibly damaging	0.52
IGL00811:Vps13c	APN	9	67,948,181 (GRCm38)	missense	probably damaging	0.99
IGL01011:Vps13c	APN	9	67,926,955 (GRCm38)	missense	probably damaging	0.98
IGL01094:Vps13c	APN	9	67,886,284 (GRCm38)	missense	probably damaging	1.00
IGL01330:Vps13c	APN	9	67,964,108 (GRCm38)	missense	probably damaging	1.00
IGL01402:Vps13c	APN	9	67,913,204 (GRCm38)	critical splice acceptor site	probably null
IGL01404:Vps13c	APN	9	67,913,204 (GRCm38)	critical splice acceptor site	probably null
IGL01470:Vps13c	APN	9	67,912,927 (GRCm38)	splice site	probably benign
IGL01615:Vps13c	APN	9	67,955,781 (GRCm38)	missense	probably benign	0.01
IGL01694:Vps13c	APN	9	67,895,349 (GRCm38)	missense	probably damaging	1.00
IGL01752:Vps13c	APN	9	67,948,228 (GRCm38)	missense	probably damaging	1.00
IGL01810:Vps13c	APN	9	67,955,780 (GRCm38)	missense	probably benign
IGL01954:Vps13c	APN	9	67,969,298 (GRCm38)	missense	probably damaging	0.98
IGL01978:Vps13c	APN	9	67,930,643 (GRCm38)	missense	probably benign	0.03
IGL01998:Vps13c	APN	9	67,955,068 (GRCm38)	splice site	probably null
IGL02201:Vps13c	APN	9	67,967,136 (GRCm38)	missense	probably damaging	1.00
IGL02205:Vps13c	APN	9	67,883,454 (GRCm38)	missense	probably damaging	1.00
IGL02303:Vps13c	APN	9	67,945,481 (GRCm38)	splice site	probably benign
IGL02322:Vps13c	APN	9	67,937,901 (GRCm38)	missense	probably benign	0.02
IGL02456:Vps13c	APN	9	67,952,976 (GRCm38)	missense	probably damaging	1.00
IGL02474:Vps13c	APN	9	67,937,876 (GRCm38)	missense	probably benign	0.00
IGL02547:Vps13c	APN	9	67,908,019 (GRCm38)	missense	possibly damaging	0.83
IGL02640:Vps13c	APN	9	67,886,248 (GRCm38)	splice site	probably benign
IGL02673:Vps13c	APN	9	67,878,098 (GRCm38)	missense	probably damaging	1.00
IGL02721:Vps13c	APN	9	67,964,149 (GRCm38)	splice site	probably benign
IGL02834:Vps13c	APN	9	67,937,855 (GRCm38)	missense	probably benign
IGL02838:Vps13c	APN	9	67,975,851 (GRCm38)	missense	probably damaging	1.00
IGL03136:Vps13c	APN	9	67,950,310 (GRCm38)	missense	probably damaging	1.00
IGL03137:Vps13c	APN	9	67,890,380 (GRCm38)	missense	probably damaging	1.00
IGL03214:Vps13c	APN	9	67,897,195 (GRCm38)	missense	probably null	0.81
IGL03240:Vps13c	APN	9	67,955,047 (GRCm38)	missense	probably benign
IGL03303:Vps13c	APN	9	67,934,504 (GRCm38)	missense	probably benign	0.27
IGL03336:Vps13c	APN	9	67,951,642 (GRCm38)	missense	possibly damaging	0.76
IGL03366:Vps13c	APN	9	67,946,026 (GRCm38)	missense	probably benign	0.00
Derivative	UTSW	9	67,930,622 (GRCm38)	missense	possibly damaging	0.79
diversion	UTSW	9	67,910,233 (GRCm38)	missense	possibly damaging	0.93
introversion	UTSW	9	67,944,046 (GRCm38)	missense	probably damaging	0.98
Inversion	UTSW	9	67,902,839 (GRCm38)	critical splice acceptor site	probably null
subversion	UTSW	9	67,908,052 (GRCm38)	missense	probably damaging	1.00
Transversion	UTSW	9	67,934,501 (GRCm38)	missense	probably damaging	0.98
3-1:Vps13c	UTSW	9	67,936,373 (GRCm38)	missense	probably benign	0.00
IGL02991:Vps13c	UTSW	9	67,913,877 (GRCm38)	missense	probably damaging	1.00
PIT4802001:Vps13c	UTSW	9	67,937,786 (GRCm38)	missense	probably damaging	1.00
R0008:Vps13c	UTSW	9	67,919,262 (GRCm38)	missense	probably benign
R0206:Vps13c	UTSW	9	67,939,162 (GRCm38)	splice site	probably benign
R0288:Vps13c	UTSW	9	67,927,366 (GRCm38)	missense	probably damaging	0.99
R0324:Vps13c	UTSW	9	67,964,309 (GRCm38)	missense	possibly damaging	0.95
R0347:Vps13c	UTSW	9	67,910,233 (GRCm38)	missense	possibly damaging	0.93
R0374:Vps13c	UTSW	9	67,886,246 (GRCm38)	splice site	probably benign
R0388:Vps13c	UTSW	9	67,922,915 (GRCm38)	splice site	probably benign
R0409:Vps13c	UTSW	9	67,951,644 (GRCm38)	missense	probably benign	0.00
R0440:Vps13c	UTSW	9	67,972,861 (GRCm38)	missense	probably damaging	1.00
R0513:Vps13c	UTSW	9	67,930,735 (GRCm38)	missense	probably benign	0.02
R0520:Vps13c	UTSW	9	67,945,851 (GRCm38)	missense	possibly damaging	0.88
R0569:Vps13c	UTSW	9	67,973,719 (GRCm38)	missense	probably damaging	0.98
R0601:Vps13c	UTSW	9	67,927,472 (GRCm38)	missense	probably benign	0.12
R0659:Vps13c	UTSW	9	67,920,935 (GRCm38)	missense	probably benign	0.11
R0667:Vps13c	UTSW	9	67,951,573 (GRCm38)	nonsense	probably null
R0670:Vps13c	UTSW	9	67,925,857 (GRCm38)	missense	probably benign	0.35
R0698:Vps13c	UTSW	9	67,889,723 (GRCm38)	missense	probably benign	0.45
R0729:Vps13c	UTSW	9	67,961,649 (GRCm38)	missense	probably damaging	1.00
R0781:Vps13c	UTSW	9	67,972,003 (GRCm38)	missense	probably damaging	1.00
R0811:Vps13c	UTSW	9	67,934,476 (GRCm38)	missense	probably benign	0.06
R0812:Vps13c	UTSW	9	67,934,476 (GRCm38)	missense	probably benign	0.06
R0839:Vps13c	UTSW	9	67,898,738 (GRCm38)	missense	probably benign
R1373:Vps13c	UTSW	9	67,927,511 (GRCm38)	missense	probably damaging	0.99
R1396:Vps13c	UTSW	9	67,955,022 (GRCm38)	missense	probably benign	0.00
R1499:Vps13c	UTSW	9	67,957,505 (GRCm38)	missense	probably benign	0.00
R1556:Vps13c	UTSW	9	67,930,711 (GRCm38)	missense	probably damaging	0.98
R1560:Vps13c	UTSW	9	67,936,463 (GRCm38)	critical splice donor site	probably null
R1584:Vps13c	UTSW	9	67,893,112 (GRCm38)	missense	possibly damaging	0.74
R1654:Vps13c	UTSW	9	67,951,687 (GRCm38)	missense	probably damaging	1.00
R1674:Vps13c	UTSW	9	67,853,703 (GRCm38)	nonsense	probably null
R1676:Vps13c	UTSW	9	67,926,962 (GRCm38)	missense	probably benign	0.20
R1695:Vps13c	UTSW	9	67,972,075 (GRCm38)	nonsense	probably null
R1710:Vps13c	UTSW	9	67,911,529 (GRCm38)	missense	probably benign	0.00
R1769:Vps13c	UTSW	9	67,965,721 (GRCm38)	missense	probably benign	0.00
R1775:Vps13c	UTSW	9	67,881,447 (GRCm38)	missense	probably damaging	1.00
R1795:Vps13c	UTSW	9	67,893,985 (GRCm38)	nonsense	probably null
R1799:Vps13c	UTSW	9	67,944,117 (GRCm38)	missense	probably damaging	0.98
R1835:Vps13c	UTSW	9	67,993,013 (GRCm38)	missense	probably benign	0.08
R1848:Vps13c	UTSW	9	67,936,340 (GRCm38)	missense	probably benign
R1903:Vps13c	UTSW	9	67,894,052 (GRCm38)	missense	probably damaging	1.00
R1944:Vps13c	UTSW	9	67,886,276 (GRCm38)	missense	probably damaging	1.00
R1945:Vps13c	UTSW	9	67,886,276 (GRCm38)	missense	probably damaging	1.00
R1951:Vps13c	UTSW	9	67,973,759 (GRCm38)	critical splice donor site	probably null
R1993:Vps13c	UTSW	9	67,975,856 (GRCm38)	missense	probably damaging	1.00
R2023:Vps13c	UTSW	9	67,936,285 (GRCm38)	splice site	probably benign
R2059:Vps13c	UTSW	9	67,860,833 (GRCm38)	missense	probably damaging	1.00
R2086:Vps13c	UTSW	9	67,950,289 (GRCm38)	missense	probably benign	0.29
R2120:Vps13c	UTSW	9	67,919,334 (GRCm38)	missense	possibly damaging	0.92
R2249:Vps13c	UTSW	9	67,988,053 (GRCm38)	critical splice donor site	probably null
R2257:Vps13c	UTSW	9	67,952,946 (GRCm38)	missense	possibly damaging	0.87
R2258:Vps13c	UTSW	9	67,953,860 (GRCm38)	missense	probably benign	0.01
R2259:Vps13c	UTSW	9	67,953,860 (GRCm38)	missense	probably benign	0.01
R2260:Vps13c	UTSW	9	67,953,860 (GRCm38)	missense	probably benign	0.01
R2265:Vps13c	UTSW	9	67,920,947 (GRCm38)	missense	possibly damaging	0.82
R2266:Vps13c	UTSW	9	67,920,947 (GRCm38)	missense	possibly damaging	0.82
R2269:Vps13c	UTSW	9	67,920,947 (GRCm38)	missense	possibly damaging	0.82
R2278:Vps13c	UTSW	9	67,939,072 (GRCm38)	missense	probably benign
R2306:Vps13c	UTSW	9	67,987,993 (GRCm38)	missense	probably damaging	0.99
R2327:Vps13c	UTSW	9	67,913,820 (GRCm38)	missense	probably damaging	0.98
R2349:Vps13c	UTSW	9	67,957,526 (GRCm38)	missense	possibly damaging	0.89
R2483:Vps13c	UTSW	9	67,975,907 (GRCm38)	critical splice donor site	probably null
R3031:Vps13c	UTSW	9	67,923,770 (GRCm38)	missense	probably benign	0.00
R3623:Vps13c	UTSW	9	67,975,907 (GRCm38)	critical splice donor site	probably null
R3870:Vps13c	UTSW	9	67,884,726 (GRCm38)	missense	probably benign	0.00
R4173:Vps13c	UTSW	9	67,936,313 (GRCm38)	missense	probably benign	0.00
R4445:Vps13c	UTSW	9	67,982,495 (GRCm38)	splice site	probably null
R4491:Vps13c	UTSW	9	67,910,193 (GRCm38)	missense	probably benign
R4505:Vps13c	UTSW	9	67,939,034 (GRCm38)	missense	probably benign	0.02
R4574:Vps13c	UTSW	9	67,951,683 (GRCm38)	missense	probably damaging	1.00
R4691:Vps13c	UTSW	9	67,952,935 (GRCm38)	missense	possibly damaging	0.95
R4766:Vps13c	UTSW	9	67,878,224 (GRCm38)	splice site	probably null
R4771:Vps13c	UTSW	9	67,929,539 (GRCm38)	missense	probably benign
R4802:Vps13c	UTSW	9	67,964,282 (GRCm38)	missense	probably damaging	1.00
R4962:Vps13c	UTSW	9	67,873,891 (GRCm38)	missense	probably damaging	1.00
R4995:Vps13c	UTSW	9	67,919,321 (GRCm38)	missense	probably benign	0.00
R5010:Vps13c	UTSW	9	67,916,379 (GRCm38)	missense	probably benign	0.19
R5183:Vps13c	UTSW	9	67,908,052 (GRCm38)	missense	probably damaging	1.00
R5226:Vps13c	UTSW	9	67,945,553 (GRCm38)	missense	probably benign	0.17
R5297:Vps13c	UTSW	9	67,878,131 (GRCm38)	missense	probably damaging	1.00
R5456:Vps13c	UTSW	9	67,927,447 (GRCm38)	missense	possibly damaging	0.53
R5494:Vps13c	UTSW	9	67,948,146 (GRCm38)	missense	probably benign	0.00
R5521:Vps13c	UTSW	9	67,951,439 (GRCm38)	missense	probably benign	0.08
R5524:Vps13c	UTSW	9	67,957,556 (GRCm38)	missense	probably damaging	1.00
R5685:Vps13c	UTSW	9	67,963,173 (GRCm38)	missense	possibly damaging	0.64
R5731:Vps13c	UTSW	9	67,895,379 (GRCm38)	missense	probably damaging	1.00
R5812:Vps13c	UTSW	9	67,982,495 (GRCm38)	splice site	probably benign
R5867:Vps13c	UTSW	9	67,982,622 (GRCm38)	splice site	probably null
R5893:Vps13c	UTSW	9	67,902,839 (GRCm38)	critical splice acceptor site	probably null
R5902:Vps13c	UTSW	9	67,934,447 (GRCm38)	missense	probably benign	0.00
R5957:Vps13c	UTSW	9	67,954,971 (GRCm38)	missense	probably damaging	1.00
R6076:Vps13c	UTSW	9	67,911,602 (GRCm38)	missense	probably damaging	1.00
R6187:Vps13c	UTSW	9	67,915,657 (GRCm38)	missense	probably damaging	1.00
R6268:Vps13c	UTSW	9	67,951,449 (GRCm38)	missense	probably benign	0.10
R6547:Vps13c	UTSW	9	67,973,365 (GRCm38)	missense	probably damaging	1.00
R6716:Vps13c	UTSW	9	67,951,467 (GRCm38)	missense	probably benign	0.00
R6837:Vps13c	UTSW	9	67,910,222 (GRCm38)	missense	probably benign
R6919:Vps13c	UTSW	9	67,927,452 (GRCm38)	missense	probably damaging	0.97
R7039:Vps13c	UTSW	9	67,937,763 (GRCm38)	missense	probably damaging	1.00
R7058:Vps13c	UTSW	9	67,923,828 (GRCm38)	missense	probably benign	0.39
R7082:Vps13c	UTSW	9	67,883,453 (GRCm38)	missense	probably damaging	1.00
R7195:Vps13c	UTSW	9	67,945,825 (GRCm38)	missense	possibly damaging	0.95
R7244:Vps13c	UTSW	9	67,889,804 (GRCm38)	missense	probably benign	0.00
R7300:Vps13c	UTSW	9	67,940,544 (GRCm38)	missense	probably benign	0.20
R7314:Vps13c	UTSW	9	67,943,340 (GRCm38)	splice site	probably null
R7352:Vps13c	UTSW	9	67,840,446 (GRCm38)	missense	possibly damaging	0.94
R7368:Vps13c	UTSW	9	67,914,073 (GRCm38)	missense	probably benign	0.23
R7411:Vps13c	UTSW	9	67,972,001 (GRCm38)	missense	probably damaging	0.98
R7497:Vps13c	UTSW	9	67,840,479 (GRCm38)	missense	probably damaging	1.00
R7516:Vps13c	UTSW	9	67,955,007 (GRCm38)	missense	possibly damaging	0.89
R7638:Vps13c	UTSW	9	67,945,509 (GRCm38)	missense	probably damaging	1.00
R7732:Vps13c	UTSW	9	67,940,516 (GRCm38)	missense	probably damaging	0.97
R7748:Vps13c	UTSW	9	67,963,089 (GRCm38)	missense	probably benign	0.03
R7779:Vps13c	UTSW	9	67,881,422 (GRCm38)	missense	probably damaging	1.00
R7788:Vps13c	UTSW	9	67,940,483 (GRCm38)	missense	probably benign	0.01
R7894:Vps13c	UTSW	9	67,926,983 (GRCm38)	missense	probably damaging	0.99
R8163:Vps13c	UTSW	9	67,950,438 (GRCm38)	missense	probably benign	0.08
R8165:Vps13c	UTSW	9	67,858,790 (GRCm38)	missense	probably benign	0.00
R8202:Vps13c	UTSW	9	67,944,046 (GRCm38)	missense	probably damaging	0.98
R8235:Vps13c	UTSW	9	67,955,781 (GRCm38)	missense	probably benign	0.01
R8235:Vps13c	UTSW	9	67,927,396 (GRCm38)	missense	probably damaging	1.00
R8253:Vps13c	UTSW	9	67,943,488 (GRCm38)	nonsense	probably null
R8261:Vps13c	UTSW	9	67,954,980 (GRCm38)	missense	probably damaging	1.00
R8348:Vps13c	UTSW	9	67,879,103 (GRCm38)	missense	possibly damaging	0.79
R8547:Vps13c	UTSW	9	67,945,566 (GRCm38)	missense	probably damaging	1.00
R8734:Vps13c	UTSW	9	67,973,403 (GRCm38)	missense	probably damaging	1.00
R8806:Vps13c	UTSW	9	67,945,828 (GRCm38)	missense	probably damaging	1.00
R8807:Vps13c	UTSW	9	67,858,840 (GRCm38)	missense	probably damaging	0.99
R8813:Vps13c	UTSW	9	67,871,284 (GRCm38)	missense	probably damaging	1.00
R8883:Vps13c	UTSW	9	67,948,197 (GRCm38)	missense	probably benign	0.10
R8885:Vps13c	UTSW	9	67,943,454 (GRCm38)	missense	probably benign
R8899:Vps13c	UTSW	9	67,934,501 (GRCm38)	missense	probably damaging	0.98
R8970:Vps13c	UTSW	9	67,945,521 (GRCm38)	missense	probably benign	0.11
R9007:Vps13c	UTSW	9	67,937,724 (GRCm38)	missense	probably benign	0.00
R9026:Vps13c	UTSW	9	67,954,581 (GRCm38)	missense	probably damaging	1.00
R9029:Vps13c	UTSW	9	67,948,147 (GRCm38)	missense	probably damaging	0.98
R9057:Vps13c	UTSW	9	67,920,927 (GRCm38)	missense	probably benign	0.00
R9105:Vps13c	UTSW	9	67,870,799 (GRCm38)	intron	probably benign
R9130:Vps13c	UTSW	9	67,929,523 (GRCm38)	missense	probably damaging	1.00
R9286:Vps13c	UTSW	9	67,972,921 (GRCm38)	missense	probably benign	0.00
R9338:Vps13c	UTSW	9	67,951,695 (GRCm38)	missense	probably damaging	1.00
R9432:Vps13c	UTSW	9	67,922,855 (GRCm38)	missense	probably benign	0.02
R9460:Vps13c	UTSW	9	67,930,622 (GRCm38)	missense	possibly damaging	0.79
R9464:Vps13c	UTSW	9	67,951,392 (GRCm38)	missense	probably damaging	1.00
R9561:Vps13c	UTSW	9	67,965,512 (GRCm38)	missense	probably damaging	1.00
R9609:Vps13c	UTSW	9	67,934,549 (GRCm38)	missense	probably damaging	1.00
R9622:Vps13c	UTSW	9	67,949,433 (GRCm38)	missense	probably damaging	1.00
R9665:Vps13c	UTSW	9	67,955,743 (GRCm38)	nonsense	probably null
R9731:Vps13c	UTSW	9	67,919,244 (GRCm38)	missense	probably benign
R9763:Vps13c	UTSW	9	67,911,578 (GRCm38)	missense	probably benign	0.00
R9774:Vps13c	UTSW	9	67,884,591 (GRCm38)	missense	possibly damaging	0.85
R9798:Vps13c	UTSW	9	67,919,364 (GRCm38)	missense	probably damaging	1.00
U24488:Vps13c	UTSW	9	67,905,916 (GRCm38)	missense	probably benign	0.13
X0021:Vps13c	UTSW	9	67,937,781 (GRCm38)	missense	probably damaging	0.99
X0058:Vps13c	UTSW	9	67,927,419 (GRCm38)	missense	probably damaging	1.00
X0065:Vps13c	UTSW	9	67,873,863 (GRCm38)	missense	probably damaging	1.00
Z1088:Vps13c	UTSW	9	67,913,975 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TCGATAATCAGTTACCAGGCAC -3'
(R):5'- AAGTTCACCAGCCCAATAGTTTAG -3'

Sequencing Primer
(F):5'- AGGCACAATGTTCCCAGTTG -3'
(R):5'- GATTTTGTACAGAAGCCACT -3'

Posted On

2016-02-04