Mutagenetix > Incidental Mutation

Incidental Mutation 'R4806:Dnah10'

370670

Institutional Source

Beutler Lab

Gene Symbol

Dnah10

Ensembl Gene

ENSMUSG00000038011

Gene Name

dynein, axonemal, heavy chain 10

Synonyms

Dnahc10

MMRRC Submission

042425-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4806 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

124802149-124911372 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 124896408 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 3591 (T3591A)

Ref Sequence

ENSEMBL: ENSMUSP00000114593 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058440] [ENSMUST00000141137]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000058440
AA Change: T3648A

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000062995
Gene: ENSMUSG00000038011
AA Change: T3648A

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	305	878	9.1e-154	PFAM
coiled coil region	1191	1218	N/A	INTRINSIC
coiled coil region	1337	1360	N/A	INTRINSIC
Pfam:DHC_N2	1374	1782	1.7e-142	PFAM
AAA	1946	2082	2.51e-1	SMART
AAA	2225	2373	6.91e-1	SMART
low complexity region	2444	2464	N/A	INTRINSIC
AAA	2567	2720	2.29e-2	SMART
Pfam:AAA_8	2886	3153	9.8e-87	PFAM
Pfam:MT	3165	3502	9.1e-53	PFAM
Pfam:AAA_9	3522	3747	2.3e-90	PFAM
Pfam:Dynein_heavy	3884	4588	7.6e-240	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000141137
AA Change: T3591A

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000114593
Gene: ENSMUSG00000038011
AA Change: T3591A

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	304	607	4.3e-57	PFAM
Pfam:DHC_N1	598	823	1.2e-39	PFAM
coiled coil region	1134	1161	N/A	INTRINSIC
coiled coil region	1280	1303	N/A	INTRINSIC
Pfam:DHC_N2	1315	1727	7.3e-135	PFAM
AAA	1889	2025	4e-3	SMART
AAA	2168	2316	1.1e-2	SMART
low complexity region	2387	2407	N/A	INTRINSIC
AAA	2510	2663	3.6e-4	SMART
Pfam:AAA_8	2829	3096	2.5e-83	PFAM
Pfam:MT	3108	3445	1.2e-50	PFAM
Pfam:AAA_9	3461	3691	6.7e-59	PFAM
Pfam:Dynein_heavy	3821	4532	1.9e-231	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000196708

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000197269

Meta Mutation Damage Score

0.3532

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.7%
20x: 93.5%

Validation Efficiency

100% (66/66)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH10 is an inner arm dynein heavy chain (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar 2008]

Allele List at MGI

All alleles(2) : Gene trapped(2)

Other mutations in this stock

Total: 61 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310022A10Rik	A	G	7: 27,265,070 (GRCm39)		probably null	Het
2410137M14Rik	T	A	17: 37,289,746 (GRCm39)	H28L	probably benign	Het
4930562C15Rik	T	C	16: 4,667,536 (GRCm39)	F309S	unknown	Het
Acd	A	G	8: 106,424,922 (GRCm39)	V406A	possibly damaging	Het
Acin1	A	T	14: 54,916,685 (GRCm39)		probably benign	Het
Agbl4	T	C	4: 110,812,834 (GRCm39)	V118A	probably damaging	Het
Arhgap5	A	G	12: 52,565,486 (GRCm39)	D819G	probably damaging	Het
BC049715	A	T	6: 136,816,927 (GRCm39)	I56F	possibly damaging	Het
C1rb	A	T	6: 124,551,908 (GRCm39)	Q270L	probably benign	Het
Cadps2	C	T	6: 23,688,859 (GRCm39)	R121Q	probably damaging	Het
Cd84	A	G	1: 171,679,688 (GRCm39)	Y122C	probably benign	Het
Cklf	C	A	8: 104,984,067 (GRCm39)	P77T	probably damaging	Het
Clrn2	T	C	5: 45,611,346 (GRCm39)	L65P	probably damaging	Het
Csde1	TCCTCGACCT	TCCT	3: 102,963,685 (GRCm39)		probably benign	Het
Csf2rb2	T	C	15: 78,169,490 (GRCm39)	D446G	probably benign	Het
Csmd3	T	C	15: 48,177,464 (GRCm39)	E358G	probably benign	Het
Dmkn	C	T	7: 30,470,667 (GRCm39)	T385I	possibly damaging	Het
Dpp9	A	G	17: 56,497,030 (GRCm39)	L734P	probably damaging	Het
Edem2	A	G	2: 155,570,913 (GRCm39)	V39A	possibly damaging	Het
Glmp	A	C	3: 88,233,320 (GRCm39)		probably benign	Het
Gm20775	T	C	Y: 10,641,885 (GRCm39)		noncoding transcript	Het
Gpr179	T	G	11: 97,240,610 (GRCm39)	D271A	possibly damaging	Het
Gtf2ird1	A	G	5: 134,412,750 (GRCm39)	V587A	probably damaging	Het
Igfn1	T	A	1: 135,895,095 (GRCm39)	T1824S	probably benign	Het
Ighmbp2	A	T	19: 3,311,589 (GRCm39)	I942N	probably damaging	Het
Ints2	A	G	11: 86,147,035 (GRCm39)	L37P	probably benign	Het
Irgq	T	A	7: 24,233,470 (GRCm39)	L437Q	probably damaging	Het
Kcnq4	A	T	4: 120,570,291 (GRCm39)	W351R	probably damaging	Het
Kif3b	G	A	2: 153,162,288 (GRCm39)	A500T	probably damaging	Het
Lpp	A	G	16: 24,480,430 (GRCm39)	D66G	probably damaging	Het
Mapkap1	G	A	2: 34,487,434 (GRCm39)		probably null	Het
Mc4r	T	A	18: 66,992,559 (GRCm39)	I185F	probably damaging	Het
Mdga1	T	C	17: 30,061,128 (GRCm39)	D621G	probably benign	Het
Med13	A	G	11: 86,189,403 (GRCm39)	S1169P	probably benign	Het
Myh11	A	T	16: 14,018,947 (GRCm39)		probably null	Het
Naip1	G	A	13: 100,562,129 (GRCm39)	A1012V	probably benign	Het
Ntn4	C	T	10: 93,480,362 (GRCm39)	R29C	probably damaging	Het
Plb1	G	A	5: 32,447,196 (GRCm39)	G321D	probably damaging	Het
Plxnd1	A	G	6: 115,937,816 (GRCm39)	V1510A	probably damaging	Het
Polr1e	T	A	4: 45,024,482 (GRCm39)	M131K	probably benign	Het
Prdm10	T	A	9: 31,241,237 (GRCm39)	*342R	probably null	Het
Prex2	T	C	1: 11,138,244 (GRCm39)	F108L	probably damaging	Het
Psmg2	T	A	18: 67,781,992 (GRCm39)	I186N	probably benign	Het
Ros1	T	A	10: 51,972,271 (GRCm39)	E1614D	probably damaging	Het
Sin3a	G	A	9: 56,994,026 (GRCm39)	V44M	probably damaging	Het
Slco1a1	G	A	6: 141,854,735 (GRCm39)	L639F	possibly damaging	Het
Smr2	T	G	5: 88,246,289 (GRCm39)	L101*	probably null	Het
Spata31d1b	C	T	13: 59,863,535 (GRCm39)	P228S	probably benign	Het
Stat5b	G	T	11: 100,681,623 (GRCm39)	H544N	probably benign	Het
Syk	A	T	13: 52,786,963 (GRCm39)	Y319F	probably benign	Het
Tln2	G	T	9: 67,239,015 (GRCm39)	T1087K	probably benign	Het
Tsc22d1	A	G	14: 76,654,428 (GRCm39)		probably null	Het
Vmn2r52	T	A	7: 9,893,169 (GRCm39)	T657S	probably damaging	Het
Vmn2r63	A	T	7: 42,576,314 (GRCm39)	S500T	probably benign	Het
Vps45	A	C	3: 95,953,725 (GRCm39)	V209G	probably benign	Het
Xrcc1	C	A	7: 24,269,905 (GRCm39)	A442E	probably benign	Het
Ythdc1	T	A	5: 86,970,704 (GRCm39)	V430E	probably damaging	Het
Zfp341	G	A	2: 154,487,786 (GRCm39)		probably benign	Het
Zfp422	A	T	6: 116,603,623 (GRCm39)	N125K	probably damaging	Het
Zfp53	T	A	17: 21,725,263 (GRCm39)	D58E	possibly damaging	Het
Zfp707	C	T	15: 75,845,000 (GRCm39)	Q66*	probably null	Het

Other mutations in Dnah10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dnah10	APN	5	124,905,667 (GRCm39)	missense	probably damaging	1.00
IGL00089:Dnah10	APN	5	124,823,680 (GRCm39)	missense	probably benign	0.01
IGL00471:Dnah10	APN	5	124,871,405 (GRCm39)	missense	probably damaging	1.00
IGL01336:Dnah10	APN	5	124,852,576 (GRCm39)	missense	probably damaging	1.00
IGL01339:Dnah10	APN	5	124,854,276 (GRCm39)	missense	probably damaging	1.00
IGL01372:Dnah10	APN	5	124,856,218 (GRCm39)	missense	probably damaging	1.00
IGL01572:Dnah10	APN	5	124,861,010 (GRCm39)	missense	probably damaging	1.00
IGL01634:Dnah10	APN	5	124,898,405 (GRCm39)	missense	probably damaging	0.98
IGL01649:Dnah10	APN	5	124,809,553 (GRCm39)	missense	probably damaging	0.97
IGL01676:Dnah10	APN	5	124,880,392 (GRCm39)	missense	possibly damaging	0.65
IGL01729:Dnah10	APN	5	124,864,529 (GRCm39)	missense	probably benign	0.10
IGL01757:Dnah10	APN	5	124,845,991 (GRCm39)	missense	probably benign	0.37
IGL01759:Dnah10	APN	5	124,832,850 (GRCm39)	missense	probably benign
IGL01767:Dnah10	APN	5	124,820,801 (GRCm39)	splice site	probably benign
IGL01769:Dnah10	APN	5	124,842,008 (GRCm39)	missense	possibly damaging	0.63
IGL01805:Dnah10	APN	5	124,860,985 (GRCm39)	missense	probably damaging	1.00
IGL02090:Dnah10	APN	5	124,866,876 (GRCm39)	missense	probably damaging	1.00
IGL02162:Dnah10	APN	5	124,881,810 (GRCm39)	missense	probably damaging	1.00
IGL02312:Dnah10	APN	5	124,896,430 (GRCm39)	missense	probably damaging	1.00
IGL02347:Dnah10	APN	5	124,910,487 (GRCm39)	critical splice acceptor site	probably null
IGL02378:Dnah10	APN	5	124,850,131 (GRCm39)	missense	probably damaging	1.00
IGL02440:Dnah10	APN	5	124,850,883 (GRCm39)	missense	probably damaging	1.00
IGL02457:Dnah10	APN	5	124,866,860 (GRCm39)	missense	probably damaging	1.00
IGL02487:Dnah10	APN	5	124,870,916 (GRCm39)	missense	possibly damaging	0.90
IGL02502:Dnah10	APN	5	124,898,351 (GRCm39)	missense	probably damaging	1.00
IGL02516:Dnah10	APN	5	124,864,395 (GRCm39)	missense	probably damaging	1.00
IGL02544:Dnah10	APN	5	124,876,069 (GRCm39)	missense	probably benign	0.26
IGL02709:Dnah10	APN	5	124,850,809 (GRCm39)	nonsense	probably null
IGL02740:Dnah10	APN	5	124,903,927 (GRCm39)	splice site	probably benign
IGL02746:Dnah10	APN	5	124,807,150 (GRCm39)	missense	possibly damaging	0.55
IGL02803:Dnah10	APN	5	124,875,078 (GRCm39)	missense	probably damaging	0.99
IGL02900:Dnah10	APN	5	124,878,886 (GRCm39)	missense	probably damaging	1.00
IGL02957:Dnah10	APN	5	124,840,197 (GRCm39)	missense	probably benign	0.07
IGL03076:Dnah10	APN	5	124,807,226 (GRCm39)	critical splice donor site	probably null
IGL03109:Dnah10	APN	5	124,841,950 (GRCm39)	missense	probably benign	0.10
IGL03181:Dnah10	APN	5	124,825,521 (GRCm39)	missense	probably damaging	0.99
IGL03185:Dnah10	APN	5	124,894,707 (GRCm39)	missense	probably damaging	1.00
IGL03199:Dnah10	APN	5	124,894,761 (GRCm39)	missense	probably benign	0.00
IGL03328:Dnah10	APN	5	124,831,354 (GRCm39)	missense	probably benign	0.06
frosty	UTSW	5	124,905,201 (GRCm39)	missense	probably damaging	1.00
H8562:Dnah10	UTSW	5	124,906,593 (GRCm39)	missense	probably damaging	1.00
I2288:Dnah10	UTSW	5	124,807,164 (GRCm39)	missense	probably benign
P0019:Dnah10	UTSW	5	124,840,130 (GRCm39)	missense	probably benign
P0037:Dnah10	UTSW	5	124,895,056 (GRCm39)	nonsense	probably null
PIT4366001:Dnah10	UTSW	5	124,852,588 (GRCm39)	missense	possibly damaging	0.95
R0004:Dnah10	UTSW	5	124,803,966 (GRCm39)	missense	probably benign
R0032:Dnah10	UTSW	5	124,877,955 (GRCm39)	missense	possibly damaging	0.94
R0032:Dnah10	UTSW	5	124,877,955 (GRCm39)	missense	possibly damaging	0.94
R0050:Dnah10	UTSW	5	124,907,808 (GRCm39)	missense	probably benign	0.00
R0066:Dnah10	UTSW	5	124,840,140 (GRCm39)	missense	probably benign	0.01
R0164:Dnah10	UTSW	5	124,860,898 (GRCm39)	missense	probably damaging	1.00
R0164:Dnah10	UTSW	5	124,860,898 (GRCm39)	missense	probably damaging	1.00
R0196:Dnah10	UTSW	5	124,911,139 (GRCm39)	missense	possibly damaging	0.80
R0312:Dnah10	UTSW	5	124,873,433 (GRCm39)	splice site	probably benign
R0321:Dnah10	UTSW	5	124,900,416 (GRCm39)	missense	probably benign	0.29
R0410:Dnah10	UTSW	5	124,832,799 (GRCm39)	missense	probably benign
R0480:Dnah10	UTSW	5	124,885,915 (GRCm39)	missense	probably damaging	1.00
R0531:Dnah10	UTSW	5	124,889,787 (GRCm39)	critical splice donor site	probably null
R0533:Dnah10	UTSW	5	124,852,314 (GRCm39)	splice site	probably null
R0599:Dnah10	UTSW	5	124,878,017 (GRCm39)	missense	probably damaging	1.00
R0686:Dnah10	UTSW	5	124,824,782 (GRCm39)	missense	possibly damaging	0.95
R0688:Dnah10	UTSW	5	124,824,782 (GRCm39)	missense	possibly damaging	0.95
R0780:Dnah10	UTSW	5	124,827,876 (GRCm39)	missense	possibly damaging	0.87
R0968:Dnah10	UTSW	5	124,906,641 (GRCm39)	missense	probably damaging	0.99
R0989:Dnah10	UTSW	5	124,875,002 (GRCm39)	missense	probably benign	0.00
R1203:Dnah10	UTSW	5	124,837,078 (GRCm39)	splice site	probably null
R1248:Dnah10	UTSW	5	124,832,887 (GRCm39)	splice site	probably benign
R1366:Dnah10	UTSW	5	124,830,390 (GRCm39)	missense	probably benign	0.41
R1434:Dnah10	UTSW	5	124,852,050 (GRCm39)	missense	probably benign	0.03
R1436:Dnah10	UTSW	5	124,839,285 (GRCm39)	missense	probably benign	0.00
R1438:Dnah10	UTSW	5	124,876,009 (GRCm39)	missense	probably benign	0.25
R1446:Dnah10	UTSW	5	124,866,860 (GRCm39)	missense	probably damaging	1.00
R1459:Dnah10	UTSW	5	124,820,750 (GRCm39)	missense	possibly damaging	0.90
R1466:Dnah10	UTSW	5	124,840,160 (GRCm39)	missense	probably benign
R1466:Dnah10	UTSW	5	124,840,160 (GRCm39)	missense	probably benign
R1479:Dnah10	UTSW	5	124,854,953 (GRCm39)	missense	possibly damaging	0.71
R1505:Dnah10	UTSW	5	124,831,303 (GRCm39)	missense	possibly damaging	0.82
R1519:Dnah10	UTSW	5	124,838,016 (GRCm39)	missense	probably damaging	0.98
R1565:Dnah10	UTSW	5	124,906,678 (GRCm39)	missense	probably damaging	1.00
R1668:Dnah10	UTSW	5	124,842,626 (GRCm39)	missense	probably benign	0.00
R1709:Dnah10	UTSW	5	124,837,155 (GRCm39)	missense	probably damaging	0.99
R1740:Dnah10	UTSW	5	124,850,254 (GRCm39)	splice site	probably null
R1828:Dnah10	UTSW	5	124,838,343 (GRCm39)	missense	probably benign	0.00
R1854:Dnah10	UTSW	5	124,881,753 (GRCm39)	missense	probably damaging	0.99
R1865:Dnah10	UTSW	5	124,909,590 (GRCm39)	splice site	probably null
R1893:Dnah10	UTSW	5	124,831,381 (GRCm39)	missense	probably benign	0.13
R1895:Dnah10	UTSW	5	124,835,494 (GRCm39)	missense	probably benign	0.00
R1906:Dnah10	UTSW	5	124,878,048 (GRCm39)	missense	probably damaging	1.00
R1953:Dnah10	UTSW	5	124,859,332 (GRCm39)	missense	probably benign	0.00
R1965:Dnah10	UTSW	5	124,852,267 (GRCm39)	missense	probably damaging	1.00
R2002:Dnah10	UTSW	5	124,911,052 (GRCm39)	missense	probably damaging	1.00
R2006:Dnah10	UTSW	5	124,906,651 (GRCm39)	missense	possibly damaging	0.58
R2037:Dnah10	UTSW	5	124,823,768 (GRCm39)	missense	probably benign	0.30
R2046:Dnah10	UTSW	5	124,873,405 (GRCm39)	missense	probably benign	0.25
R2074:Dnah10	UTSW	5	124,891,738 (GRCm39)	missense	probably damaging	1.00
R2081:Dnah10	UTSW	5	124,852,045 (GRCm39)	missense	possibly damaging	0.88
R2257:Dnah10	UTSW	5	124,838,301 (GRCm39)	missense	probably damaging	1.00
R2272:Dnah10	UTSW	5	124,808,530 (GRCm39)	missense	probably benign	0.00
R2293:Dnah10	UTSW	5	124,896,285 (GRCm39)	missense	probably damaging	0.97
R2323:Dnah10	UTSW	5	124,819,064 (GRCm39)	missense	probably damaging	1.00
R2435:Dnah10	UTSW	5	124,839,929 (GRCm39)	critical splice donor site	probably null
R2571:Dnah10	UTSW	5	124,852,542 (GRCm39)	missense	probably damaging	1.00
R2898:Dnah10	UTSW	5	124,894,734 (GRCm39)	missense	probably damaging	1.00
R2937:Dnah10	UTSW	5	124,896,476 (GRCm39)	critical splice donor site	probably null
R3439:Dnah10	UTSW	5	124,873,322 (GRCm39)	missense	possibly damaging	0.91
R3548:Dnah10	UTSW	5	124,824,694 (GRCm39)	missense	possibly damaging	0.50
R3881:Dnah10	UTSW	5	124,850,095 (GRCm39)	missense	probably benign	0.37
R4015:Dnah10	UTSW	5	124,854,990 (GRCm39)	missense	probably benign	0.25
R4261:Dnah10	UTSW	5	124,807,201 (GRCm39)	missense	possibly damaging	0.95
R4277:Dnah10	UTSW	5	124,809,394 (GRCm39)	missense	probably benign	0.28
R4299:Dnah10	UTSW	5	124,896,989 (GRCm39)	missense	probably damaging	1.00
R4613:Dnah10	UTSW	5	124,839,933 (GRCm39)	splice site	probably null
R4651:Dnah10	UTSW	5	124,806,207 (GRCm39)	missense	probably benign	0.20
R4652:Dnah10	UTSW	5	124,806,207 (GRCm39)	missense	probably benign	0.20
R4664:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4665:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4666:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4691:Dnah10	UTSW	5	124,852,581 (GRCm39)	missense	probably damaging	1.00
R4755:Dnah10	UTSW	5	124,824,809 (GRCm39)	missense	probably benign	0.01
R4839:Dnah10	UTSW	5	124,850,196 (GRCm39)	missense	probably damaging	1.00
R4903:Dnah10	UTSW	5	124,894,812 (GRCm39)	missense	probably damaging	1.00
R5018:Dnah10	UTSW	5	124,839,260 (GRCm39)	missense	possibly damaging	0.79
R5101:Dnah10	UTSW	5	124,909,577 (GRCm39)	missense	possibly damaging	0.51
R5105:Dnah10	UTSW	5	124,888,546 (GRCm39)	missense	probably benign	0.01
R5119:Dnah10	UTSW	5	124,856,322 (GRCm39)	missense	probably damaging	1.00
R5139:Dnah10	UTSW	5	124,876,024 (GRCm39)	missense	probably damaging	0.99
R5242:Dnah10	UTSW	5	124,864,484 (GRCm39)	missense	probably benign	0.00
R5262:Dnah10	UTSW	5	124,862,220 (GRCm39)	missense	probably damaging	1.00
R5277:Dnah10	UTSW	5	124,905,201 (GRCm39)	missense	probably damaging	1.00
R5293:Dnah10	UTSW	5	124,868,851 (GRCm39)	missense	probably benign	0.01
R5322:Dnah10	UTSW	5	124,850,630 (GRCm39)	missense	probably damaging	1.00
R5371:Dnah10	UTSW	5	124,820,693 (GRCm39)	missense	probably benign	0.16
R5468:Dnah10	UTSW	5	124,907,557 (GRCm39)	missense	probably damaging	1.00
R5470:Dnah10	UTSW	5	124,830,232 (GRCm39)	missense	probably benign
R5587:Dnah10	UTSW	5	124,870,977 (GRCm39)	missense	probably benign	0.10
R5724:Dnah10	UTSW	5	124,819,090 (GRCm39)	missense	probably benign	0.27
R5797:Dnah10	UTSW	5	124,898,450 (GRCm39)	missense	probably benign	0.00
R5812:Dnah10	UTSW	5	124,824,810 (GRCm39)	missense	probably benign	0.01
R5846:Dnah10	UTSW	5	124,900,437 (GRCm39)	missense	possibly damaging	0.80
R5930:Dnah10	UTSW	5	124,868,855 (GRCm39)	critical splice donor site	probably null
R5961:Dnah10	UTSW	5	124,888,546 (GRCm39)	missense	probably benign	0.01
R5970:Dnah10	UTSW	5	124,885,793 (GRCm39)	missense	probably benign
R6021:Dnah10	UTSW	5	124,814,048 (GRCm39)	missense	probably damaging	1.00
R6043:Dnah10	UTSW	5	124,878,924 (GRCm39)	missense	probably damaging	1.00
R6073:Dnah10	UTSW	5	124,896,274 (GRCm39)	missense	probably benign	0.09
R6080:Dnah10	UTSW	5	124,882,961 (GRCm39)	missense	possibly damaging	0.71
R6093:Dnah10	UTSW	5	124,830,238 (GRCm39)	missense	probably benign	0.18
R6155:Dnah10	UTSW	5	124,862,239 (GRCm39)	missense	probably damaging	1.00
R6155:Dnah10	UTSW	5	124,847,663 (GRCm39)	missense	probably damaging	1.00
R6162:Dnah10	UTSW	5	124,900,382 (GRCm39)	missense	probably benign	0.02
R6238:Dnah10	UTSW	5	124,820,743 (GRCm39)	missense	probably damaging	0.97
R6248:Dnah10	UTSW	5	124,871,283 (GRCm39)	splice site	probably null
R6275:Dnah10	UTSW	5	124,862,248 (GRCm39)	missense	probably damaging	1.00
R6297:Dnah10	UTSW	5	124,852,144 (GRCm39)	missense	possibly damaging	0.55
R6388:Dnah10	UTSW	5	124,906,710 (GRCm39)	missense	probably benign	0.00
R6458:Dnah10	UTSW	5	124,886,333 (GRCm39)	missense	probably damaging	1.00
R6504:Dnah10	UTSW	5	124,839,846 (GRCm39)	missense	possibly damaging	0.50
R6518:Dnah10	UTSW	5	124,835,419 (GRCm39)	missense	probably damaging	0.99
R6627:Dnah10	UTSW	5	124,907,097 (GRCm39)	missense	probably damaging	1.00
R6701:Dnah10	UTSW	5	124,837,223 (GRCm39)	missense	probably benign	0.45
R6702:Dnah10	UTSW	5	124,882,869 (GRCm39)	missense	probably damaging	1.00
R6745:Dnah10	UTSW	5	124,885,876 (GRCm39)	missense	probably damaging	1.00
R6784:Dnah10	UTSW	5	124,854,890 (GRCm39)	missense	probably damaging	0.99
R6807:Dnah10	UTSW	5	124,867,064 (GRCm39)	splice site	probably null
R6932:Dnah10	UTSW	5	124,898,514 (GRCm39)	missense	possibly damaging	0.75
R7007:Dnah10	UTSW	5	124,864,490 (GRCm39)	missense	probably damaging	1.00
R7091:Dnah10	UTSW	5	124,893,206 (GRCm39)	missense	probably benign	0.37
R7138:Dnah10	UTSW	5	124,900,009 (GRCm39)	missense	probably damaging	1.00
R7144:Dnah10	UTSW	5	124,900,006 (GRCm39)	missense	probably damaging	0.98
R7231:Dnah10	UTSW	5	124,890,892 (GRCm39)	missense	probably benign	0.19
R7278:Dnah10	UTSW	5	124,868,855 (GRCm39)	critical splice donor site	probably null
R7284:Dnah10	UTSW	5	124,909,662 (GRCm39)	missense	probably benign	0.37
R7322:Dnah10	UTSW	5	124,898,333 (GRCm39)	missense	probably benign	0.08
R7523:Dnah10	UTSW	5	124,824,803 (GRCm39)	missense	probably damaging	0.97
R7565:Dnah10	UTSW	5	124,876,095 (GRCm39)	missense	probably damaging	1.00
R7593:Dnah10	UTSW	5	124,823,608 (GRCm39)	missense	probably benign	0.21
R7606:Dnah10	UTSW	5	124,894,776 (GRCm39)	missense	probably benign	0.00
R7835:Dnah10	UTSW	5	124,854,298 (GRCm39)	missense	probably damaging	1.00
R7898:Dnah10	UTSW	5	124,859,425 (GRCm39)	missense	probably damaging	1.00
R7972:Dnah10	UTSW	5	124,803,949 (GRCm39)	missense	probably benign
R7999:Dnah10	UTSW	5	124,802,322 (GRCm39)	missense	probably benign	0.06
R8017:Dnah10	UTSW	5	124,877,949 (GRCm39)	missense	probably benign	0.03
R8032:Dnah10	UTSW	5	124,823,676 (GRCm39)	missense	probably damaging	0.98
R8052:Dnah10	UTSW	5	124,905,575 (GRCm39)	missense	probably benign	0.00
R8088:Dnah10	UTSW	5	124,831,330 (GRCm39)	missense	probably benign	0.00
R8169:Dnah10	UTSW	5	124,877,946 (GRCm39)	missense	probably damaging	1.00
R8178:Dnah10	UTSW	5	124,832,790 (GRCm39)	missense	probably benign	0.11
R8200:Dnah10	UTSW	5	124,905,524 (GRCm39)	missense	probably damaging	1.00
R8210:Dnah10	UTSW	5	124,827,858 (GRCm39)	missense	probably benign	0.29
R8294:Dnah10	UTSW	5	124,859,410 (GRCm39)	missense	probably damaging	1.00
R8338:Dnah10	UTSW	5	124,909,566 (GRCm39)	missense	probably damaging	1.00
R8404:Dnah10	UTSW	5	124,850,606 (GRCm39)	missense	probably damaging	1.00
R8469:Dnah10	UTSW	5	124,813,895 (GRCm39)	missense	probably damaging	1.00
R8537:Dnah10	UTSW	5	124,893,164 (GRCm39)	missense	probably damaging	0.97
R8701:Dnah10	UTSW	5	124,803,911 (GRCm39)	missense	probably benign	0.00
R8723:Dnah10	UTSW	5	124,891,685 (GRCm39)	missense	probably damaging	0.99
R8770:Dnah10	UTSW	5	124,852,410 (GRCm39)	missense	possibly damaging	0.94
R8838:Dnah10	UTSW	5	124,842,614 (GRCm39)	missense	probably benign	0.09
R8879:Dnah10	UTSW	5	124,895,181 (GRCm39)	missense	probably damaging	1.00
R8928:Dnah10	UTSW	5	124,866,828 (GRCm39)	missense	probably damaging	0.98
R8932:Dnah10	UTSW	5	124,878,015 (GRCm39)	missense	possibly damaging	0.96
R8945:Dnah10	UTSW	5	124,891,006 (GRCm39)	missense	probably damaging	0.99
R8990:Dnah10	UTSW	5	124,814,057 (GRCm39)	missense
R9001:Dnah10	UTSW	5	124,852,515 (GRCm39)	missense	probably damaging	1.00
R9006:Dnah10	UTSW	5	124,820,783 (GRCm39)	missense	probably benign	0.23
R9060:Dnah10	UTSW	5	124,905,141 (GRCm39)	missense	probably damaging	1.00
R9085:Dnah10	UTSW	5	124,839,237 (GRCm39)	missense
R9133:Dnah10	UTSW	5	124,859,423 (GRCm39)	missense	probably damaging	1.00
R9155:Dnah10	UTSW	5	124,907,475 (GRCm39)	missense	probably damaging	0.99
R9220:Dnah10	UTSW	5	124,871,437 (GRCm39)	missense	probably benign	0.05
R9234:Dnah10	UTSW	5	124,818,989 (GRCm39)	missense	possibly damaging	0.94
R9264:Dnah10	UTSW	5	124,813,900 (GRCm39)	missense	probably damaging	1.00
R9266:Dnah10	UTSW	5	124,845,990 (GRCm39)	missense	probably benign	0.00
R9386:Dnah10	UTSW	5	124,871,507 (GRCm39)	critical splice donor site	probably null
R9446:Dnah10	UTSW	5	124,823,677 (GRCm39)	missense	probably damaging	1.00
R9484:Dnah10	UTSW	5	124,900,508 (GRCm39)	missense	probably damaging	1.00
R9594:Dnah10	UTSW	5	124,907,107 (GRCm39)	missense	probably damaging	1.00
R9691:Dnah10	UTSW	5	124,852,249 (GRCm39)	missense	probably damaging	0.98
RF015:Dnah10	UTSW	5	124,895,141 (GRCm39)	missense	probably damaging	1.00
RF021:Dnah10	UTSW	5	124,854,971 (GRCm39)	missense	probably damaging	1.00
T0975:Dnah10	UTSW	5	124,840,130 (GRCm39)	missense	probably benign
U24488:Dnah10	UTSW	5	124,891,044 (GRCm39)	missense	probably damaging	1.00
X0017:Dnah10	UTSW	5	124,842,761 (GRCm39)	missense	probably benign	0.22
Z1176:Dnah10	UTSW	5	124,852,419 (GRCm39)	missense	probably benign	0.11
Z1177:Dnah10	UTSW	5	124,819,019 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah10	UTSW	5	124,895,052 (GRCm39)	critical splice acceptor site	probably null
Z1177:Dnah10	UTSW	5	124,824,683 (GRCm39)	missense	possibly damaging	0.64

Predicted Primers

PCR Primer
(F):5'- CCAAATTAGTGGTCTCCAGTTTTG -3'
(R):5'- TTCCATGGAGAGACTGGAGC -3'

Sequencing Primer
(F):5'- TTCCTGAAGCAGCTCGAGATGTC -3'
(R):5'- GCCACCAGGGATCAAGATGC -3'

Posted On

2016-02-04