Incidental Mutation 'R4809:Dock9'
| ID |
370943 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dock9
|
| Ensembl Gene |
ENSMUSG00000025558 |
| Gene Name |
dedicator of cytokinesis 9 |
| Synonyms |
D14Wsu89e, Zizimin1, B230309H04Rik |
| MMRRC Submission |
042428-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4809 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
121542046-121797837 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 121546596 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Asparagine
at position 1989
(Y1989N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000148834
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040700]
[ENSMUST00000100299]
[ENSMUST00000212181]
[ENSMUST00000212376]
[ENSMUST00000212416]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000040700
AA Change: Y2014N
PolyPhen 2
Score 0.232 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000047881
Gene: ENSMUSG00000025558
AA Change: Y2014N
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
151 |
5.6e-36 |
PFAM |
|
PH
|
172 |
280 |
1.38e-16 |
SMART |
|
Blast:PH
|
297 |
372 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
631 |
822 |
5.3e-51 |
PFAM |
|
Pfam:DHR-2
|
1523 |
2068 |
2.1e-212 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100299
AA Change: Y1959N
PolyPhen 2
Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000097872
Gene: ENSMUSG00000025558
AA Change: Y1959N
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
153 |
1.5e-32 |
PFAM |
|
PH
|
174 |
282 |
1.38e-16 |
SMART |
|
Blast:PH
|
299 |
374 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
632 |
825 |
1.3e-59 |
PFAM |
|
low complexity region
|
1752 |
1763 |
N/A |
INTRINSIC |
|
Pfam:Ded_cyto
|
1836 |
2013 |
2.4e-69 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000211803
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212181
AA Change: Y1989N
PolyPhen 2
Score 0.365 (Sensitivity: 0.90; Specificity: 0.89)
|
| Predicted Effect |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212376
AA Change: Y1981N
PolyPhen 2
Score 0.057 (Sensitivity: 0.94; Specificity: 0.84)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212416
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
96% (96/100) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
A |
G |
14: 32,662,631 (GRCm38) |
V459A |
probably benign |
Het |
| Abca12 |
C |
T |
1: 71,278,856 (GRCm38) |
A1840T |
probably benign |
Het |
| Abhd6 |
T |
G |
14: 8,039,771 (GRCm38) |
M1R |
probably null |
Het |
| Abl1 |
T |
C |
2: 31,800,242 (GRCm38) |
L572P |
probably damaging |
Het |
| Adamts2 |
C |
A |
11: 50,803,690 (GRCm38) |
S1101R |
probably benign |
Het |
| Adgra2 |
G |
A |
8: 27,110,479 (GRCm38) |
W200* |
probably null |
Het |
| AI661453 |
C |
A |
17: 47,467,187 (GRCm38) |
|
probably benign |
Het |
| Aldh1l2 |
A |
G |
10: 83,506,632 (GRCm38) |
F438S |
probably damaging |
Het |
| Ankrd49 |
G |
A |
9: 14,781,214 (GRCm38) |
T218I |
possibly damaging |
Het |
| Ano7 |
T |
C |
1: 93,394,566 (GRCm38) |
F410L |
probably benign |
Het |
| Aox4 |
T |
A |
1: 58,266,649 (GRCm38) |
F1271I |
probably damaging |
Het |
| Aqr |
T |
C |
2: 114,175,214 (GRCm38) |
|
probably benign |
Het |
| Arhgap42 |
A |
G |
9: 9,180,117 (GRCm38) |
S54P |
probably damaging |
Het |
| Aunip |
C |
A |
4: 134,511,139 (GRCm38) |
D16E |
possibly damaging |
Het |
| Btbd7 |
A |
G |
12: 102,793,744 (GRCm38) |
|
probably null |
Het |
| Cabp4 |
T |
C |
19: 4,139,291 (GRCm38) |
H89R |
probably benign |
Het |
| Ccni |
AAA |
AAACTAA |
5: 93,187,570 (GRCm38) |
|
probably benign |
Het |
| Chfr |
C |
T |
5: 110,158,834 (GRCm38) |
H410Y |
probably damaging |
Het |
| Churc1 |
C |
A |
12: 76,782,897 (GRCm38) |
L111M |
probably damaging |
Het |
| Clasp1 |
C |
T |
1: 118,461,250 (GRCm38) |
T113I |
probably benign |
Het |
| Col12a1 |
T |
A |
9: 79,693,567 (GRCm38) |
Q745L |
probably benign |
Het |
| Col20a1 |
T |
C |
2: 180,998,661 (GRCm38) |
L537P |
probably damaging |
Het |
| Creb5 |
A |
T |
6: 53,610,426 (GRCm38) |
E47V |
probably null |
Het |
| Csnk1d |
A |
T |
11: 120,963,842 (GRCm38) |
|
probably benign |
Het |
| Cts6 |
A |
T |
13: 61,202,181 (GRCm38) |
W29R |
probably damaging |
Het |
| Dbt |
T |
A |
3: 116,546,343 (GRCm38) |
I420N |
probably damaging |
Het |
| Det1 |
C |
A |
7: 78,843,807 (GRCm38) |
D150Y |
probably damaging |
Het |
| Dlk2 |
A |
G |
17: 46,299,014 (GRCm38) |
|
probably null |
Het |
| Dnmt3a |
A |
T |
12: 3,900,352 (GRCm38) |
I639F |
probably damaging |
Het |
| Dsg4 |
A |
T |
18: 20,466,621 (GRCm38) |
T765S |
possibly damaging |
Het |
| Epha5 |
C |
T |
5: 84,105,891 (GRCm38) |
D548N |
possibly damaging |
Het |
| Fam189a1 |
G |
A |
7: 64,776,740 (GRCm38) |
T159I |
probably damaging |
Het |
| Fam227b |
T |
A |
2: 126,116,125 (GRCm38) |
Y240F |
possibly damaging |
Het |
| Fbxw21 |
C |
T |
9: 109,143,390 (GRCm38) |
V395I |
probably damaging |
Het |
| Fn1 |
C |
A |
1: 71,652,800 (GRCm38) |
|
probably benign |
Het |
| Fpr-rs3 |
A |
T |
17: 20,624,421 (GRCm38) |
S153T |
probably benign |
Het |
| Frem2 |
A |
G |
3: 53,653,895 (GRCm38) |
F1064L |
probably benign |
Het |
| Gas2l3 |
CACTCGTCATACT |
CACT |
10: 89,430,958 (GRCm38) |
|
probably benign |
Het |
| Gjd2 |
C |
T |
2: 114,011,541 (GRCm38) |
G152R |
probably damaging |
Het |
| Gpr75 |
T |
C |
11: 30,892,154 (GRCm38) |
I353T |
possibly damaging |
Het |
| Grb7 |
T |
C |
11: 98,451,436 (GRCm38) |
V145A |
possibly damaging |
Het |
| Igkv4-73 |
G |
A |
6: 69,197,823 (GRCm38) |
R40W |
unknown |
Het |
| Kif1c |
C |
T |
11: 70,726,357 (GRCm38) |
A839V |
probably benign |
Het |
| Krt31 |
G |
A |
11: 100,049,922 (GRCm38) |
A125V |
possibly damaging |
Het |
| Lamb1 |
A |
G |
12: 31,278,526 (GRCm38) |
Y163C |
probably damaging |
Het |
| Mars |
G |
T |
10: 127,300,215 (GRCm38) |
T535K |
probably damaging |
Het |
| Mdc1 |
T |
C |
17: 35,849,101 (GRCm38) |
|
probably null |
Het |
| Micu1 |
C |
T |
10: 59,740,822 (GRCm38) |
H167Y |
probably benign |
Het |
| Minos1 |
C |
G |
4: 139,130,957 (GRCm38) |
W10S |
probably damaging |
Het |
| Mrgprb1 |
C |
T |
7: 48,447,991 (GRCm38) |
V58I |
possibly damaging |
Het |
| Ncoa7 |
T |
A |
10: 30,771,762 (GRCm38) |
E6V |
possibly damaging |
Het |
| Nectin3 |
A |
C |
16: 46,448,160 (GRCm38) |
|
probably benign |
Het |
| Olfr1085 |
T |
A |
2: 86,657,685 (GRCm38) |
M258L |
possibly damaging |
Het |
| Olfr1294 |
C |
T |
2: 111,537,611 (GRCm38) |
C226Y |
probably benign |
Het |
| Olfr46 |
A |
G |
7: 140,611,074 (GRCm38) |
K295E |
probably damaging |
Het |
| Olfr598 |
T |
A |
7: 103,328,523 (GRCm38) |
Y12* |
probably null |
Het |
| Pex16 |
T |
C |
2: 92,376,638 (GRCm38) |
S54P |
probably damaging |
Het |
| Pik3cg |
A |
T |
12: 32,204,081 (GRCm38) |
S636T |
possibly damaging |
Het |
| Plin5 |
A |
G |
17: 56,116,855 (GRCm38) |
S27P |
probably benign |
Het |
| Ptch1 |
A |
T |
13: 63,513,708 (GRCm38) |
D1068E |
probably damaging |
Het |
| Ptprq |
T |
C |
10: 107,563,175 (GRCm38) |
T1960A |
probably damaging |
Het |
| Rap1gap2 |
T |
C |
11: 74,407,974 (GRCm38) |
|
probably benign |
Het |
| Rcc2 |
G |
A |
4: 140,717,042 (GRCm38) |
R348Q |
probably damaging |
Het |
| Rhbdd3 |
C |
A |
11: 5,105,949 (GRCm38) |
A377D |
probably damaging |
Het |
| Rpl7 |
T |
G |
1: 16,101,965 (GRCm38) |
|
probably benign |
Het |
| Scn11a |
G |
T |
9: 119,819,870 (GRCm38) |
D42E |
probably benign |
Het |
| Scube3 |
C |
T |
17: 28,165,173 (GRCm38) |
R549W |
probably damaging |
Het |
| Sil1 |
A |
T |
18: 35,325,375 (GRCm38) |
M189K |
probably damaging |
Het |
| Slc39a6 |
G |
A |
18: 24,585,474 (GRCm38) |
Q225* |
probably null |
Het |
| Slc7a15 |
A |
T |
12: 8,539,002 (GRCm38) |
C182S |
probably benign |
Het |
| Spata21 |
G |
A |
4: 141,097,120 (GRCm38) |
|
probably null |
Het |
| Stim2 |
T |
C |
5: 54,110,613 (GRCm38) |
V417A |
probably damaging |
Het |
| Szt2 |
T |
C |
4: 118,388,985 (GRCm38) |
D993G |
probably damaging |
Het |
| Tet3 |
A |
G |
6: 83,402,946 (GRCm38) |
S747P |
probably benign |
Het |
| Tmem86a |
C |
G |
7: 47,052,930 (GRCm38) |
S34R |
possibly damaging |
Het |
| Top2b |
T |
A |
14: 16,383,125 (GRCm38) |
S38T |
probably benign |
Het |
| Trim33 |
A |
T |
3: 103,329,256 (GRCm38) |
T561S |
possibly damaging |
Het |
| Ttc39a |
C |
T |
4: 109,416,021 (GRCm38) |
Q25* |
probably null |
Het |
| Urb1 |
A |
G |
16: 90,759,842 (GRCm38) |
I1816T |
possibly damaging |
Het |
| Usp24 |
T |
C |
4: 106,413,676 (GRCm38) |
|
probably null |
Het |
| Usp36 |
A |
C |
11: 118,263,070 (GRCm38) |
L840R |
probably damaging |
Het |
| Usp50 |
C |
A |
2: 126,777,853 (GRCm38) |
|
probably benign |
Het |
| Vangl2 |
A |
G |
1: 172,009,663 (GRCm38) |
V193A |
possibly damaging |
Het |
| Vmn1r62 |
T |
A |
7: 5,675,867 (GRCm38) |
H182Q |
probably benign |
Het |
| Vmn2r124 |
A |
T |
17: 18,073,745 (GRCm38) |
Y698F |
probably benign |
Het |
| Wls |
C |
T |
3: 159,897,445 (GRCm38) |
T165I |
probably benign |
Het |
| Zfp808 |
G |
T |
13: 62,171,292 (GRCm38) |
E112* |
probably null |
Het |
|
| Other mutations in Dock9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Dock9
|
APN |
14 |
121,668,468 (GRCm38) |
missense |
probably benign |
0.12 |
|
IGL00817:Dock9
|
APN |
14 |
121,698,291 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL00923:Dock9
|
APN |
14 |
121,607,092 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01385:Dock9
|
APN |
14 |
121,580,583 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01567:Dock9
|
APN |
14 |
121,653,084 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01767:Dock9
|
APN |
14 |
121,622,870 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL01811:Dock9
|
APN |
14 |
121,559,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02512:Dock9
|
APN |
14 |
121,619,538 (GRCm38) |
splice site |
probably benign |
|
|
IGL02525:Dock9
|
APN |
14 |
121,640,126 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02550:Dock9
|
APN |
14 |
121,698,312 (GRCm38) |
start codon destroyed |
probably null |
0.07 |
|
IGL02559:Dock9
|
APN |
14 |
121,625,147 (GRCm38) |
splice site |
probably benign |
|
|
IGL02666:Dock9
|
APN |
14 |
121,580,699 (GRCm38) |
missense |
probably benign |
0.42 |
|
IGL02674:Dock9
|
APN |
14 |
121,595,611 (GRCm38) |
splice site |
probably null |
|
|
IGL02795:Dock9
|
APN |
14 |
121,639,978 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL03074:Dock9
|
APN |
14 |
121,607,270 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL03095:Dock9
|
APN |
14 |
121,639,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03294:Dock9
|
APN |
14 |
121,641,623 (GRCm38) |
splice site |
probably benign |
|
|
R0036:Dock9
|
UTSW |
14 |
121,622,853 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0050:Dock9
|
UTSW |
14 |
121,607,225 (GRCm38) |
missense |
probably benign |
0.43 |
|
R0050:Dock9
|
UTSW |
14 |
121,607,225 (GRCm38) |
missense |
probably benign |
0.43 |
|
R0164:Dock9
|
UTSW |
14 |
121,597,665 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0164:Dock9
|
UTSW |
14 |
121,597,665 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0270:Dock9
|
UTSW |
14 |
121,575,999 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0494:Dock9
|
UTSW |
14 |
121,662,584 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R0726:Dock9
|
UTSW |
14 |
121,651,768 (GRCm38) |
nonsense |
probably null |
|
|
R1029:Dock9
|
UTSW |
14 |
121,599,684 (GRCm38) |
splice site |
probably null |
|
|
R1214:Dock9
|
UTSW |
14 |
121,586,316 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1231:Dock9
|
UTSW |
14 |
121,575,950 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R1535:Dock9
|
UTSW |
14 |
121,546,064 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1629:Dock9
|
UTSW |
14 |
121,543,574 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R1637:Dock9
|
UTSW |
14 |
121,651,775 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R1733:Dock9
|
UTSW |
14 |
121,626,880 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1772:Dock9
|
UTSW |
14 |
121,609,798 (GRCm38) |
missense |
probably benign |
0.07 |
|
R1855:Dock9
|
UTSW |
14 |
121,640,159 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1888:Dock9
|
UTSW |
14 |
121,625,205 (GRCm38) |
missense |
probably benign |
0.18 |
|
R1888:Dock9
|
UTSW |
14 |
121,625,205 (GRCm38) |
missense |
probably benign |
0.18 |
|
R1901:Dock9
|
UTSW |
14 |
121,625,153 (GRCm38) |
splice site |
probably null |
|
|
R1920:Dock9
|
UTSW |
14 |
121,583,380 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1987:Dock9
|
UTSW |
14 |
121,591,830 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3035:Dock9
|
UTSW |
14 |
121,606,837 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R3851:Dock9
|
UTSW |
14 |
121,629,086 (GRCm38) |
splice site |
probably null |
|
|
R4020:Dock9
|
UTSW |
14 |
121,606,855 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4021:Dock9
|
UTSW |
14 |
121,626,912 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R4089:Dock9
|
UTSW |
14 |
121,583,471 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4258:Dock9
|
UTSW |
14 |
121,581,442 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4423:Dock9
|
UTSW |
14 |
121,562,053 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4561:Dock9
|
UTSW |
14 |
121,559,007 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4604:Dock9
|
UTSW |
14 |
121,668,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4646:Dock9
|
UTSW |
14 |
121,586,246 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4647:Dock9
|
UTSW |
14 |
121,586,246 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4776:Dock9
|
UTSW |
14 |
121,610,097 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R4865:Dock9
|
UTSW |
14 |
121,543,505 (GRCm38) |
makesense |
probably null |
|
|
R4951:Dock9
|
UTSW |
14 |
121,653,135 (GRCm38) |
missense |
probably benign |
0.35 |
|
R5151:Dock9
|
UTSW |
14 |
121,578,170 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5359:Dock9
|
UTSW |
14 |
121,653,060 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R5366:Dock9
|
UTSW |
14 |
121,578,203 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5502:Dock9
|
UTSW |
14 |
121,610,182 (GRCm38) |
splice site |
probably null |
|
|
R5579:Dock9
|
UTSW |
14 |
121,599,695 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5753:Dock9
|
UTSW |
14 |
121,634,625 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5836:Dock9
|
UTSW |
14 |
121,681,351 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5858:Dock9
|
UTSW |
14 |
121,628,792 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5890:Dock9
|
UTSW |
14 |
121,668,408 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6075:Dock9
|
UTSW |
14 |
121,545,973 (GRCm38) |
missense |
probably benign |
|
|
R6298:Dock9
|
UTSW |
14 |
121,634,594 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6306:Dock9
|
UTSW |
14 |
121,562,080 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6321:Dock9
|
UTSW |
14 |
121,546,021 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6330:Dock9
|
UTSW |
14 |
121,605,243 (GRCm38) |
start codon destroyed |
probably null |
0.00 |
|
R6719:Dock9
|
UTSW |
14 |
121,610,027 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6784:Dock9
|
UTSW |
14 |
121,543,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6826:Dock9
|
UTSW |
14 |
121,622,918 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6830:Dock9
|
UTSW |
14 |
121,622,918 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6838:Dock9
|
UTSW |
14 |
121,546,596 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R6868:Dock9
|
UTSW |
14 |
121,586,264 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6919:Dock9
|
UTSW |
14 |
121,643,152 (GRCm38) |
missense |
probably benign |
0.42 |
|
R6989:Dock9
|
UTSW |
14 |
121,627,379 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7539:Dock9
|
UTSW |
14 |
121,581,436 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7645:Dock9
|
UTSW |
14 |
121,597,663 (GRCm38) |
missense |
probably benign |
0.44 |
|
R7875:Dock9
|
UTSW |
14 |
121,625,984 (GRCm38) |
nonsense |
probably null |
|
|
R7900:Dock9
|
UTSW |
14 |
121,546,079 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R8040:Dock9
|
UTSW |
14 |
121,651,794 (GRCm38) |
missense |
probably benign |
0.06 |
|
R8420:Dock9
|
UTSW |
14 |
121,546,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,681,435 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,627,389 (GRCm38) |
missense |
probably benign |
0.40 |
|
R8514:Dock9
|
UTSW |
14 |
121,658,787 (GRCm38) |
missense |
probably benign |
0.25 |
|
R8691:Dock9
|
UTSW |
14 |
121,640,105 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R8804:Dock9
|
UTSW |
14 |
121,605,183 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8894:Dock9
|
UTSW |
14 |
121,622,961 (GRCm38) |
missense |
probably benign |
0.10 |
|
R8900:Dock9
|
UTSW |
14 |
121,580,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9069:Dock9
|
UTSW |
14 |
121,628,912 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9218:Dock9
|
UTSW |
14 |
121,668,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9233:Dock9
|
UTSW |
14 |
121,583,369 (GRCm38) |
missense |
probably benign |
0.09 |
|
R9236:Dock9
|
UTSW |
14 |
121,639,558 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9285:Dock9
|
UTSW |
14 |
121,595,600 (GRCm38) |
missense |
probably benign |
|
|
R9451:Dock9
|
UTSW |
14 |
121,550,189 (GRCm38) |
splice site |
probably benign |
|
|
R9461:Dock9
|
UTSW |
14 |
121,605,189 (GRCm38) |
missense |
probably benign |
0.05 |
|
R9484:Dock9
|
UTSW |
14 |
121,581,432 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9517:Dock9
|
UTSW |
14 |
121,591,824 (GRCm38) |
missense |
probably benign |
0.07 |
|
R9542:Dock9
|
UTSW |
14 |
121,627,363 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9694:Dock9
|
UTSW |
14 |
121,581,379 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9701:Dock9
|
UTSW |
14 |
121,639,571 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9703:Dock9
|
UTSW |
14 |
121,544,577 (GRCm38) |
makesense |
probably null |
|
|
R9726:Dock9
|
UTSW |
14 |
121,597,737 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R9741:Dock9
|
UTSW |
14 |
121,640,104 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Dock9
|
UTSW |
14 |
121,555,275 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Dock9
|
UTSW |
14 |
121,651,782 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCTGTCTCTTGAACCAGAACAG -3'
(R):5'- TGATCCTGACTGACTTGCTTAAAC -3'
Sequencing Primer
(F):5'- CTCTTGAACCAGAACAGTGCTATGG -3'
(R):5'- TAAACAGCCTTTGGACTCCATGG -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation