Incidental Mutation 'R4810:Cfap44'
| ID |
371036 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cfap44
|
| Ensembl Gene |
ENSMUSG00000071550 |
| Gene Name |
cilia and flagella associated protein 44 |
| Synonyms |
Wdr52, 6330444M21Rik, D16Ertd642e |
| MMRRC Submission |
042429-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4810 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
44215159-44302791 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 44271898 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 1217
(I1217T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113908
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099742]
[ENSMUST00000120049]
|
| AlphaFold |
E9Q5M6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000099742
AA Change: I1217T
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000097331
Gene: ENSMUSG00000071550
AA Change: I1217T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
Blast:WD40
|
161 |
201 |
1e-7 |
BLAST |
|
WD40
|
204 |
246 |
4.58e1 |
SMART |
|
WD40
|
249 |
288 |
4.62e-1 |
SMART |
|
Blast:WD40
|
292 |
337 |
2e-15 |
BLAST |
|
WD40
|
342 |
381 |
4.8e-2 |
SMART |
|
WD40
|
447 |
486 |
4.95e-4 |
SMART |
|
WD40
|
491 |
532 |
2.64e2 |
SMART |
|
WD40
|
552 |
591 |
2.98e-7 |
SMART |
|
Blast:WD40
|
595 |
634 |
1e-19 |
BLAST |
|
coiled coil region
|
669 |
711 |
N/A |
INTRINSIC |
|
WD40
|
780 |
820 |
3.82e1 |
SMART |
|
WD40
|
830 |
872 |
2.4e-2 |
SMART |
|
coiled coil region
|
907 |
955 |
N/A |
INTRINSIC |
|
coiled coil region
|
1101 |
1122 |
N/A |
INTRINSIC |
|
low complexity region
|
1266 |
1295 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1325 |
N/A |
INTRINSIC |
|
coiled coil region
|
1402 |
1459 |
N/A |
INTRINSIC |
|
low complexity region
|
1476 |
1488 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1523 |
N/A |
INTRINSIC |
|
coiled coil region
|
1543 |
1607 |
N/A |
INTRINSIC |
|
coiled coil region
|
1630 |
1731 |
N/A |
INTRINSIC |
|
coiled coil region
|
1795 |
1822 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000120049
AA Change: I1217T
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000113908
Gene: ENSMUSG00000071550
AA Change: I1217T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
Blast:WD40
|
161 |
201 |
1e-7 |
BLAST |
|
WD40
|
204 |
246 |
4.58e1 |
SMART |
|
WD40
|
249 |
288 |
4.62e-1 |
SMART |
|
Blast:WD40
|
292 |
337 |
2e-15 |
BLAST |
|
WD40
|
342 |
381 |
4.8e-2 |
SMART |
|
WD40
|
447 |
486 |
4.95e-4 |
SMART |
|
WD40
|
491 |
532 |
2.64e2 |
SMART |
|
WD40
|
552 |
591 |
2.98e-7 |
SMART |
|
Blast:WD40
|
595 |
634 |
1e-19 |
BLAST |
|
coiled coil region
|
669 |
711 |
N/A |
INTRINSIC |
|
WD40
|
780 |
820 |
3.82e1 |
SMART |
|
WD40
|
830 |
872 |
2.4e-2 |
SMART |
|
coiled coil region
|
907 |
955 |
N/A |
INTRINSIC |
|
coiled coil region
|
1101 |
1122 |
N/A |
INTRINSIC |
|
low complexity region
|
1266 |
1295 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1325 |
N/A |
INTRINSIC |
|
coiled coil region
|
1402 |
1459 |
N/A |
INTRINSIC |
|
low complexity region
|
1476 |
1488 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1523 |
N/A |
INTRINSIC |
|
coiled coil region
|
1543 |
1607 |
N/A |
INTRINSIC |
|
coiled coil region
|
1630 |
1731 |
N/A |
INTRINSIC |
|
coiled coil region
|
1795 |
1822 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.2868 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.1%
|
| Validation Efficiency |
99% (93/94) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete male sterility, asthenozoospermia, and teratozoospermia characterized by multiple sperm axonemal defects. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
T |
C |
12: 71,236,216 (GRCm39) |
V1189A |
possibly damaging |
Het |
| A3galt2 |
T |
C |
4: 128,649,356 (GRCm39) |
|
probably null |
Het |
| Abca12 |
T |
C |
1: 71,342,771 (GRCm39) |
D903G |
probably benign |
Het |
| Abcc12 |
T |
C |
8: 87,287,471 (GRCm39) |
M125V |
probably damaging |
Het |
| Adad1 |
A |
G |
3: 37,146,183 (GRCm39) |
N517S |
probably damaging |
Het |
| Ankrd44 |
A |
G |
1: 54,774,302 (GRCm39) |
|
probably benign |
Het |
| Armc7 |
A |
G |
11: 115,379,787 (GRCm39) |
I162V |
probably benign |
Het |
| Art3 |
T |
A |
5: 92,562,108 (GRCm39) |
V343D |
possibly damaging |
Het |
| Bcl9l |
A |
G |
9: 44,419,650 (GRCm39) |
T1106A |
probably damaging |
Het |
| Ccdc141 |
T |
C |
2: 76,876,099 (GRCm39) |
N644D |
possibly damaging |
Het |
| Ccdc154 |
T |
C |
17: 25,382,472 (GRCm39) |
L98S |
probably damaging |
Het |
| Ccne1 |
A |
G |
7: 37,799,018 (GRCm39) |
W237R |
probably damaging |
Het |
| Cd33 |
T |
C |
7: 43,182,134 (GRCm39) |
I104V |
probably damaging |
Het |
| Ceacam1 |
A |
T |
7: 25,173,945 (GRCm39) |
*237K |
probably null |
Het |
| Ces1e |
T |
A |
8: 93,935,259 (GRCm39) |
I398F |
probably benign |
Het |
| Clns1a |
T |
C |
7: 97,363,224 (GRCm39) |
S199P |
probably benign |
Het |
| Cntn4 |
C |
A |
6: 106,632,572 (GRCm39) |
T532K |
probably benign |
Het |
| Col11a2 |
C |
T |
17: 34,276,086 (GRCm39) |
S470L |
probably damaging |
Het |
| Cst5 |
A |
T |
2: 149,247,463 (GRCm39) |
R60* |
probably null |
Het |
| Cxcr6 |
A |
T |
9: 123,639,227 (GRCm39) |
D83V |
probably damaging |
Het |
| Dis3l2 |
T |
C |
1: 86,975,296 (GRCm39) |
V774A |
probably damaging |
Het |
| Dusp15 |
A |
G |
2: 152,787,374 (GRCm39) |
L79P |
probably damaging |
Het |
| Elapor1 |
T |
A |
3: 108,377,327 (GRCm39) |
|
probably benign |
Het |
| Eml6 |
A |
T |
11: 29,705,011 (GRCm39) |
V1511E |
possibly damaging |
Het |
| Epha5 |
C |
T |
5: 84,253,750 (GRCm39) |
D548N |
possibly damaging |
Het |
| Fam227b |
A |
G |
2: 125,829,859 (GRCm39) |
F450L |
probably benign |
Het |
| Fam91a1 |
T |
A |
15: 58,306,589 (GRCm39) |
L452Q |
probably damaging |
Het |
| Fbxo44 |
T |
C |
4: 148,240,903 (GRCm39) |
Y199C |
probably damaging |
Het |
| Fgd3 |
A |
G |
13: 49,443,126 (GRCm39) |
S149P |
probably benign |
Het |
| Gabra4 |
T |
C |
5: 71,781,325 (GRCm39) |
E362G |
probably damaging |
Het |
| Galnt14 |
T |
C |
17: 73,819,116 (GRCm39) |
I325V |
probably damaging |
Het |
| Gas2l3 |
CACTCGTCATACT |
CACT |
10: 89,266,820 (GRCm39) |
|
probably benign |
Het |
| Gm10088 |
G |
T |
16: 18,847,081 (GRCm39) |
|
noncoding transcript |
Het |
| Grik5 |
T |
C |
7: 24,714,922 (GRCm39) |
N691D |
probably damaging |
Het |
| Grm1 |
C |
G |
10: 10,658,438 (GRCm39) |
D351H |
probably damaging |
Het |
| Grm8 |
T |
C |
6: 27,761,295 (GRCm39) |
S310G |
possibly damaging |
Het |
| Gtf2h2 |
A |
G |
13: 100,617,510 (GRCm39) |
|
probably null |
Het |
| Hhex |
G |
T |
19: 37,428,103 (GRCm39) |
L49F |
probably damaging |
Het |
| Hkdc1 |
T |
A |
10: 62,247,304 (GRCm39) |
R159S |
probably benign |
Het |
| Iqcm |
A |
G |
8: 76,615,281 (GRCm39) |
Y454C |
probably damaging |
Het |
| Kcnh8 |
G |
A |
17: 53,212,248 (GRCm39) |
|
probably null |
Het |
| Larp4b |
A |
G |
13: 9,208,627 (GRCm39) |
T427A |
probably benign |
Het |
| Mtmr3 |
A |
T |
11: 4,448,046 (GRCm39) |
N297K |
probably benign |
Het |
| Nek8 |
G |
A |
11: 78,058,629 (GRCm39) |
T557I |
probably benign |
Het |
| Nlrp9c |
A |
C |
7: 26,077,602 (GRCm39) |
|
probably null |
Het |
| Nmrk1 |
T |
A |
19: 18,617,273 (GRCm39) |
D48E |
probably benign |
Het |
| Npepps |
G |
A |
11: 97,131,759 (GRCm39) |
T365I |
probably damaging |
Het |
| Obscn |
G |
A |
11: 58,922,417 (GRCm39) |
T5921M |
possibly damaging |
Het |
| Or8b44 |
C |
A |
9: 38,410,620 (GRCm39) |
Y218* |
probably null |
Het |
| Or8c9 |
A |
G |
9: 38,241,690 (GRCm39) |
E269G |
probably benign |
Het |
| Otud7b |
C |
T |
3: 96,043,918 (GRCm39) |
A23V |
probably damaging |
Het |
| Pcdhga9 |
G |
A |
18: 37,871,601 (GRCm39) |
A477T |
possibly damaging |
Het |
| Plekha7 |
A |
T |
7: 115,744,173 (GRCm39) |
I663N |
probably damaging |
Het |
| Plscr1l1 |
A |
G |
9: 92,236,683 (GRCm39) |
D190G |
probably damaging |
Het |
| Polk |
A |
T |
13: 96,620,003 (GRCm39) |
S732R |
possibly damaging |
Het |
| Ppfia2 |
A |
G |
10: 106,751,551 (GRCm39) |
I1166V |
probably benign |
Het |
| Ppp2r5a |
C |
T |
1: 191,088,589 (GRCm39) |
|
probably benign |
Het |
| Prkaa2 |
T |
C |
4: 104,897,011 (GRCm39) |
K401E |
probably damaging |
Het |
| Ptpn23 |
A |
G |
9: 110,218,204 (GRCm39) |
Y611H |
possibly damaging |
Het |
| Rab31 |
C |
T |
17: 66,028,998 (GRCm39) |
|
probably null |
Het |
| Rad51ap2 |
T |
A |
12: 11,507,406 (GRCm39) |
C443S |
probably damaging |
Het |
| Ralgapa1 |
A |
G |
12: 55,841,778 (GRCm39) |
|
probably null |
Het |
| Rev3l |
T |
C |
10: 39,699,721 (GRCm39) |
L1406P |
probably benign |
Het |
| Rnaset2b |
T |
A |
17: 7,259,167 (GRCm39) |
D48E |
probably benign |
Het |
| Rnf13 |
G |
T |
3: 57,703,693 (GRCm39) |
M105I |
probably damaging |
Het |
| Rnf150 |
T |
C |
8: 83,716,991 (GRCm39) |
V166A |
possibly damaging |
Het |
| Rps6kc1 |
C |
A |
1: 190,541,160 (GRCm39) |
R381L |
probably damaging |
Het |
| Rspo2 |
C |
T |
15: 43,033,216 (GRCm39) |
R2H |
probably benign |
Het |
| Septin8 |
A |
G |
11: 53,425,416 (GRCm39) |
D103G |
probably damaging |
Het |
| Sirt4 |
A |
G |
5: 115,618,508 (GRCm39) |
W189R |
probably damaging |
Het |
| Slco6d1 |
T |
C |
1: 98,350,979 (GRCm39) |
V110A |
possibly damaging |
Het |
| Sncaip |
C |
A |
18: 53,040,271 (GRCm39) |
Q822K |
possibly damaging |
Het |
| Spg11 |
A |
C |
2: 121,890,277 (GRCm39) |
F2070V |
probably damaging |
Het |
| Sptb |
A |
T |
12: 76,669,971 (GRCm39) |
Y452* |
probably null |
Het |
| Srsf4 |
C |
T |
4: 131,627,413 (GRCm39) |
|
probably benign |
Het |
| Tead1 |
C |
A |
7: 112,441,073 (GRCm39) |
|
probably null |
Het |
| Tmem156 |
G |
T |
5: 65,248,790 (GRCm39) |
|
probably benign |
Het |
| Tmem169 |
A |
G |
1: 72,337,311 (GRCm39) |
D82G |
probably benign |
Het |
| Tmem260 |
A |
G |
14: 48,709,930 (GRCm39) |
E51G |
probably damaging |
Het |
| Trim36 |
G |
T |
18: 46,305,536 (GRCm39) |
N470K |
probably benign |
Het |
| Trps1 |
T |
A |
15: 50,685,692 (GRCm39) |
T158S |
probably benign |
Het |
| Ube2c |
A |
G |
2: 164,614,482 (GRCm39) |
*180W |
probably null |
Het |
| Ube2i |
T |
C |
17: 25,484,121 (GRCm39) |
D45G |
probably benign |
Het |
| Uggt2 |
A |
C |
14: 119,250,933 (GRCm39) |
L1188R |
probably damaging |
Het |
| Uroc1 |
T |
C |
6: 90,340,135 (GRCm39) |
I680T |
probably damaging |
Het |
| Vmn2r2 |
T |
A |
3: 64,044,883 (GRCm39) |
M88L |
probably damaging |
Het |
| Zfp248 |
G |
A |
6: 118,406,807 (GRCm39) |
R261C |
possibly damaging |
Het |
| Zfp418 |
G |
T |
7: 7,185,846 (GRCm39) |
R603L |
possibly damaging |
Het |
| Zmpste24 |
T |
A |
4: 120,918,251 (GRCm39) |
Y457F |
probably damaging |
Het |
|
| Other mutations in Cfap44 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Cfap44
|
APN |
16 |
44,227,767 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00952:Cfap44
|
APN |
16 |
44,241,638 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL01340:Cfap44
|
APN |
16 |
44,224,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01530:Cfap44
|
APN |
16 |
44,269,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02083:Cfap44
|
APN |
16 |
44,257,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02088:Cfap44
|
APN |
16 |
44,271,991 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02142:Cfap44
|
APN |
16 |
44,241,507 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02311:Cfap44
|
APN |
16 |
44,225,134 (GRCm39) |
splice site |
probably benign |
|
|
IGL02574:Cfap44
|
APN |
16 |
44,301,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02893:Cfap44
|
APN |
16 |
44,237,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02959:Cfap44
|
APN |
16 |
44,291,230 (GRCm39) |
splice site |
probably benign |
|
|
IGL03291:Cfap44
|
APN |
16 |
44,227,674 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
feldgrau
|
UTSW |
16 |
44,254,029 (GRCm39) |
nonsense |
probably null |
|
|
I2288:Cfap44
|
UTSW |
16 |
44,269,501 (GRCm39) |
nonsense |
probably null |
|
|
R0023:Cfap44
|
UTSW |
16 |
44,241,583 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0023:Cfap44
|
UTSW |
16 |
44,241,583 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0036:Cfap44
|
UTSW |
16 |
44,259,432 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R0139:Cfap44
|
UTSW |
16 |
44,253,785 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0145:Cfap44
|
UTSW |
16 |
44,288,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0193:Cfap44
|
UTSW |
16 |
44,269,573 (GRCm39) |
splice site |
probably null |
|
|
R0238:Cfap44
|
UTSW |
16 |
44,242,681 (GRCm39) |
missense |
probably benign |
|
|
R0238:Cfap44
|
UTSW |
16 |
44,242,681 (GRCm39) |
missense |
probably benign |
|
|
R0288:Cfap44
|
UTSW |
16 |
44,236,257 (GRCm39) |
splice site |
probably benign |
|
|
R0367:Cfap44
|
UTSW |
16 |
44,253,839 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0452:Cfap44
|
UTSW |
16 |
44,252,308 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0531:Cfap44
|
UTSW |
16 |
44,221,789 (GRCm39) |
start codon destroyed |
probably benign |
0.01 |
|
R0722:Cfap44
|
UTSW |
16 |
44,225,039 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0801:Cfap44
|
UTSW |
16 |
44,242,849 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1209:Cfap44
|
UTSW |
16 |
44,242,780 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1215:Cfap44
|
UTSW |
16 |
44,239,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1385:Cfap44
|
UTSW |
16 |
44,291,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1400:Cfap44
|
UTSW |
16 |
44,241,575 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1415:Cfap44
|
UTSW |
16 |
44,301,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1475:Cfap44
|
UTSW |
16 |
44,254,175 (GRCm39) |
splice site |
probably benign |
|
|
R1901:Cfap44
|
UTSW |
16 |
44,242,737 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1902:Cfap44
|
UTSW |
16 |
44,242,737 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1903:Cfap44
|
UTSW |
16 |
44,242,737 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2023:Cfap44
|
UTSW |
16 |
44,236,375 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2126:Cfap44
|
UTSW |
16 |
44,230,838 (GRCm39) |
missense |
probably benign |
0.40 |
|
R2147:Cfap44
|
UTSW |
16 |
44,272,047 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2233:Cfap44
|
UTSW |
16 |
44,271,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2439:Cfap44
|
UTSW |
16 |
44,301,609 (GRCm39) |
unclassified |
probably benign |
|
|
R3015:Cfap44
|
UTSW |
16 |
44,230,832 (GRCm39) |
missense |
probably benign |
0.40 |
|
R4178:Cfap44
|
UTSW |
16 |
44,272,216 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4421:Cfap44
|
UTSW |
16 |
44,242,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4516:Cfap44
|
UTSW |
16 |
44,294,227 (GRCm39) |
nonsense |
probably null |
|
|
R4742:Cfap44
|
UTSW |
16 |
44,269,615 (GRCm39) |
splice site |
probably null |
|
|
R4766:Cfap44
|
UTSW |
16 |
44,236,246 (GRCm39) |
splice site |
probably null |
|
|
R4955:Cfap44
|
UTSW |
16 |
44,295,640 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5058:Cfap44
|
UTSW |
16 |
44,240,567 (GRCm39) |
splice site |
probably null |
|
|
R5164:Cfap44
|
UTSW |
16 |
44,301,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5172:Cfap44
|
UTSW |
16 |
44,269,556 (GRCm39) |
missense |
probably benign |
|
|
R5344:Cfap44
|
UTSW |
16 |
44,236,763 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5519:Cfap44
|
UTSW |
16 |
44,224,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5572:Cfap44
|
UTSW |
16 |
44,301,668 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5601:Cfap44
|
UTSW |
16 |
44,280,549 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5625:Cfap44
|
UTSW |
16 |
44,280,710 (GRCm39) |
splice site |
probably null |
|
|
R5638:Cfap44
|
UTSW |
16 |
44,275,894 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5727:Cfap44
|
UTSW |
16 |
44,255,805 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5950:Cfap44
|
UTSW |
16 |
44,300,210 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6057:Cfap44
|
UTSW |
16 |
44,269,460 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6063:Cfap44
|
UTSW |
16 |
44,250,255 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6221:Cfap44
|
UTSW |
16 |
44,257,549 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6277:Cfap44
|
UTSW |
16 |
44,257,669 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6322:Cfap44
|
UTSW |
16 |
44,254,029 (GRCm39) |
nonsense |
probably null |
|
|
R6836:Cfap44
|
UTSW |
16 |
44,224,442 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6854:Cfap44
|
UTSW |
16 |
44,269,391 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6889:Cfap44
|
UTSW |
16 |
44,224,495 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7233:Cfap44
|
UTSW |
16 |
44,242,771 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7294:Cfap44
|
UTSW |
16 |
44,225,256 (GRCm39) |
intron |
probably benign |
|
|
R7298:Cfap44
|
UTSW |
16 |
44,301,775 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7332:Cfap44
|
UTSW |
16 |
44,250,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7410:Cfap44
|
UTSW |
16 |
44,288,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7455:Cfap44
|
UTSW |
16 |
44,225,147 (GRCm39) |
intron |
probably benign |
|
|
R7456:Cfap44
|
UTSW |
16 |
44,252,305 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7491:Cfap44
|
UTSW |
16 |
44,291,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7587:Cfap44
|
UTSW |
16 |
44,224,469 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7698:Cfap44
|
UTSW |
16 |
44,254,149 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7717:Cfap44
|
UTSW |
16 |
44,250,298 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7953:Cfap44
|
UTSW |
16 |
44,234,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7994:Cfap44
|
UTSW |
16 |
44,252,501 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8043:Cfap44
|
UTSW |
16 |
44,234,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8238:Cfap44
|
UTSW |
16 |
44,235,668 (GRCm39) |
splice site |
probably null |
|
|
R8338:Cfap44
|
UTSW |
16 |
44,239,698 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8678:Cfap44
|
UTSW |
16 |
44,295,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Cfap44
|
UTSW |
16 |
44,225,085 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8785:Cfap44
|
UTSW |
16 |
44,275,895 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8922:Cfap44
|
UTSW |
16 |
44,272,030 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9005:Cfap44
|
UTSW |
16 |
44,280,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9020:Cfap44
|
UTSW |
16 |
44,257,522 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9110:Cfap44
|
UTSW |
16 |
44,255,923 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9111:Cfap44
|
UTSW |
16 |
44,252,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9126:Cfap44
|
UTSW |
16 |
44,295,619 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9187:Cfap44
|
UTSW |
16 |
44,225,144 (GRCm39) |
intron |
probably benign |
|
|
R9194:Cfap44
|
UTSW |
16 |
44,288,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9251:Cfap44
|
UTSW |
16 |
44,229,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9334:Cfap44
|
UTSW |
16 |
44,239,654 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9336:Cfap44
|
UTSW |
16 |
44,242,807 (GRCm39) |
missense |
probably damaging |
0.97 |
|
V1662:Cfap44
|
UTSW |
16 |
44,269,501 (GRCm39) |
nonsense |
probably null |
|
|
X0060:Cfap44
|
UTSW |
16 |
44,269,437 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1088:Cfap44
|
UTSW |
16 |
44,221,829 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Cfap44
|
UTSW |
16 |
44,252,407 (GRCm39) |
missense |
probably benign |
0.04 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCGCCAGTCCAAAGGTAGAG -3'
(R):5'- GTTTGAGGAACCCTACTAGCC -3'
Sequencing Primer
(F):5'- CAGTCCAAAGGTAGAGGGTTAATAAC -3'
(R):5'- GAGCCCCCAGATCCTGTTC -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation