Mutagenetix > Incidental Mutation

Incidental Mutation 'R4825:Ehmt2'

371467

Institutional Source

Beutler Lab

Gene Symbol

Ehmt2

Ensembl Gene

ENSMUSG00000013787

Gene Name

euchromatic histone lysine N-methyltransferase 2

Synonyms

KMT1C, D17Ertd710e, NG36, G9a, Bat8

MMRRC Submission

042441-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R4825 (G1)

Quality Score

213

Status

Not validated

Chromosome

Chromosomal Location

35117445-35133028 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to G at 35125940 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Proline to Arginine at position 211 (P211R)

Ref Sequence

ENSEMBL: ENSMUSP00000121838 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000013931] [ENSMUST00000078061] [ENSMUST00000097342] [ENSMUST00000114033] [ENSMUST00000124846] [ENSMUST00000137071]

AlphaFold

Q9Z148

Predicted Effect

probably benign
Transcript: ENSMUST00000013931

SMART Domains

Protein: ENSMUSP00000013931
Gene: ENSMUSG00000013787

Domain	Start	End	E-Value	Type
low complexity region	2	47	N/A	INTRINSIC
coiled coil region	336	385	N/A	INTRINSIC
low complexity region	407	424	N/A	INTRINSIC
low complexity region	604	627	N/A	INTRINSIC
ANK	737	766	2.52e-6	SMART
ANK	770	799	1.19e-2	SMART
ANK	803	833	4.71e-6	SMART
ANK	837	866	2.9e-6	SMART
ANK	870	899	1e0	SMART
ANK	903	932	1.53e-5	SMART
PreSET	976	1075	2.44e-40	SMART
SET	1091	1214	4.08e-46	SMART
PostSET	1217	1233	2.84e-1	SMART
low complexity region	1245	1260	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000078061

SMART Domains

Protein: ENSMUSP00000077208
Gene: ENSMUSG00000013787

Domain	Start	End	E-Value	Type
low complexity region	2	23	N/A	INTRINSIC
coiled coil region	279	328	N/A	INTRINSIC
low complexity region	350	367	N/A	INTRINSIC
low complexity region	513	536	N/A	INTRINSIC
ANK	646	675	2.52e-6	SMART
ANK	679	708	1.19e-2	SMART
ANK	712	742	4.71e-6	SMART
ANK	746	775	2.9e-6	SMART
ANK	779	808	1e0	SMART
ANK	812	841	1.53e-5	SMART
PreSET	885	984	2.44e-40	SMART
SET	1000	1123	4.08e-46	SMART
PostSET	1126	1142	2.84e-1	SMART
low complexity region	1154	1169	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000097342

SMART Domains

Protein: ENSMUSP00000094955
Gene: ENSMUSG00000013787

Domain	Start	End	E-Value	Type
low complexity region	2	47	N/A	INTRINSIC
coiled coil region	336	385	N/A	INTRINSIC
low complexity region	407	424	N/A	INTRINSIC
low complexity region	570	593	N/A	INTRINSIC
ANK	703	732	2.52e-6	SMART
ANK	736	765	1.19e-2	SMART
ANK	769	799	4.71e-6	SMART
ANK	803	832	2.9e-6	SMART
ANK	836	865	1e0	SMART
ANK	869	898	1.53e-5	SMART
PreSET	942	1041	2.44e-40	SMART
SET	1057	1180	4.08e-46	SMART
PostSET	1183	1199	2.84e-1	SMART
low complexity region	1211	1226	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000114033

SMART Domains

Protein: ENSMUSP00000109667
Gene: ENSMUSG00000013787

Domain	Start	End	E-Value	Type
low complexity region	2	23	N/A	INTRINSIC
coiled coil region	279	328	N/A	INTRINSIC
low complexity region	350	367	N/A	INTRINSIC
low complexity region	547	570	N/A	INTRINSIC
ANK	680	709	2.52e-6	SMART
ANK	713	742	1.19e-2	SMART
ANK	746	776	4.71e-6	SMART
ANK	780	809	2.9e-6	SMART
ANK	813	842	1e0	SMART
ANK	846	875	1.53e-5	SMART
PreSET	919	1018	2.44e-40	SMART
SET	1034	1157	4.08e-46	SMART
PostSET	1160	1176	2.84e-1	SMART
low complexity region	1188	1203	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124002

Predicted Effect

probably benign
Transcript: ENSMUST00000124846
AA Change: P211R

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000121838
Gene: ENSMUSG00000013787
AA Change: P211R

Domain	Start	End	E-Value	Type
low complexity region	115	138	N/A	INTRINSIC
low complexity region	204	215	N/A	INTRINSIC
ANK	258	287	2.52e-6	SMART
ANK	291	320	1.19e-2	SMART
ANK	324	354	4.71e-6	SMART
ANK	358	387	2.9e-6	SMART
ANK	391	420	1e0	SMART
Pfam:Ank	424	442	3.4e-4	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000131915

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000145201

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000146418

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000138500

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150786

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000145624

Predicted Effect

probably benign
Transcript: ENSMUST00000137071

SMART Domains

Protein: ENSMUSP00000134749
Gene: ENSMUSG00000013787

Domain	Start	End	E-Value	Type
ANK	23	52	1.19e-2	SMART
ANK	56	86	4.71e-6	SMART
ANK	90	119	2.9e-6	SMART
low complexity region	143	154	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000172921

SMART Domains

Protein: ENSMUSP00000134089
Gene: ENSMUSG00000013787

Domain	Start	End	E-Value	Type
ANK	24	53	1.19e-2	SMART
ANK	57	87	4.71e-6	SMART
ANK	89	118	1e0	SMART
ANK	122	151	1.53e-5	SMART

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.8%
20x: 93.8%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality around E9.5-E12.5. Mutant embryos are developmentally delayed. Conditional deletion in germ cells results in infertility and arrest of meiosis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 130 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700012B07Rik	C	A	11: 109,682,498 (GRCm39)	L229F	probably benign	Het
A930002H24Rik	A	C	17: 64,170,603 (GRCm39)	S62A	unknown	Het
Abca12	T	A	1: 71,341,844 (GRCm39)	Q1039L	possibly damaging	Het
Adgrg5	T	A	8: 95,668,362 (GRCm39)	F476I	possibly damaging	Het
Alms1	A	G	6: 85,655,227 (GRCm39)	K2789E	probably damaging	Het
Arrdc2	G	A	8: 71,291,921 (GRCm39)		probably null	Het
Atp2b1	T	A	10: 98,845,426 (GRCm39)	I743K	probably damaging	Het
Atp6v1c2	C	T	12: 17,339,061 (GRCm39)	G230D	probably benign	Het
AU040320	G	A	4: 126,685,586 (GRCm39)	C54Y	probably damaging	Het
BC024139	C	T	15: 76,004,517 (GRCm39)	V680I	possibly damaging	Het
Bckdhb	A	G	9: 83,870,958 (GRCm39)	D156G	probably damaging	Het
Bltp3a	G	A	17: 28,096,368 (GRCm39)	A107T	probably damaging	Het
Canx	T	A	11: 50,199,636 (GRCm39)	D143V	probably benign	Het
Ccdc180	T	A	4: 45,912,794 (GRCm39)	V591E	possibly damaging	Het
Ccno	T	C	13: 113,124,633 (GRCm39)	S68P	probably benign	Het
Cdc45	C	T	16: 18,603,613 (GRCm39)	E527K	probably damaging	Het
Cep290	T	A	10: 100,324,210 (GRCm39)	D14E	probably damaging	Het
Cgnl1	A	G	9: 71,537,806 (GRCm39)	V1238A	probably benign	Het
Ciz1	C	T	2: 32,261,753 (GRCm39)	A455V	probably damaging	Het
Coro2b	T	A	9: 62,361,905 (GRCm39)	Y86F	probably benign	Het
Csf2ra	C	T	19: 61,214,990 (GRCm39)	R158Q	probably benign	Het
Cubn	A	T	2: 13,330,036 (GRCm39)	I2615N	probably damaging	Het
Dhx8	C	T	11: 101,628,996 (GRCm39)	R129*	probably null	Het
Disc1	T	A	8: 125,862,041 (GRCm39)	M471K	possibly damaging	Het
Dmxl2	G	T	9: 54,311,325 (GRCm39)	L1799I	probably benign	Het
Dnah2	A	G	11: 69,314,031 (GRCm39)	S4108P	probably damaging	Het
Ecpas	G	A	4: 58,850,911 (GRCm39)	L421F	probably damaging	Het
Eif4g3	A	G	4: 137,921,392 (GRCm39)	D1557G	probably benign	Het
Epha5	T	C	5: 84,381,699 (GRCm39)	D384G	probably damaging	Het
Etl4	A	G	2: 20,811,738 (GRCm39)	I1274V	probably damaging	Het
Fhip1a	G	A	3: 85,580,739 (GRCm39)	P489S	possibly damaging	Het
Fip1l1	G	A	5: 74,748,866 (GRCm39)		probably null	Het
Fubp1	T	C	3: 151,923,527 (GRCm39)		probably null	Het
Glul	T	C	1: 153,778,790 (GRCm39)	V33A	probably benign	Het
Gm4846	A	G	1: 166,319,237 (GRCm39)	F167S	probably damaging	Het
Heatr6	T	A	11: 83,649,148 (GRCm39)	L168M	probably damaging	Het
Hif1a	T	A	12: 73,979,175 (GRCm39)	I233N	probably damaging	Het
Hivep2	T	A	10: 14,007,063 (GRCm39)	H1220Q	possibly damaging	Het
Igkv8-21	T	C	6: 70,292,410 (GRCm39)	I9M	probably benign	Het
Izumo1	T	A	7: 45,274,411 (GRCm39)	C62*	probably null	Het
Jakmip3	G	A	7: 138,628,495 (GRCm39)	E424K	probably damaging	Het
Klhl2	A	G	8: 65,205,847 (GRCm39)	V358A	probably damaging	Het
Klk10	C	G	7: 43,433,022 (GRCm39)	D139E	probably damaging	Het
Klk14	T	C	7: 43,341,500 (GRCm39)	C51R	probably damaging	Het
Klk1b5	T	G	7: 43,494,814 (GRCm39)	I99S	probably damaging	Het
L3hypdh	T	C	12: 72,124,167 (GRCm39)	T258A	probably benign	Het
Lrp5	A	G	19: 3,664,292 (GRCm39)	Y812H	probably damaging	Het
Lrrc40	T	A	3: 157,766,967 (GRCm39)	L474*	probably null	Het
Mkks	A	T	2: 136,722,575 (GRCm39)	M194K	probably benign	Het
Mmp20	A	G	9: 7,654,121 (GRCm39)	D347G	probably damaging	Het
Mmp27	A	G	9: 7,581,195 (GRCm39)	E460G	probably damaging	Het
Mms22l	T	C	4: 24,536,226 (GRCm39)	F605S	probably damaging	Het
Mpzl3	A	G	9: 44,979,627 (GRCm39)	S193G	probably benign	Het
Muc4	A	T	16: 32,570,565 (GRCm39)	T542S	probably benign	Het
Muc5b	T	C	7: 141,422,202 (GRCm39)	L4446P	possibly damaging	Het
Mxi1	C	A	19: 53,358,769 (GRCm39)	S131*	probably null	Het
Nanog	G	T	6: 122,690,299 (GRCm39)	A210S	probably benign	Het
Nrcam	C	T	12: 44,622,769 (GRCm39)	Q988*	probably null	Het
Nsg1	C	A	5: 38,316,391 (GRCm39)		probably benign	Het
Ogfod3	G	A	11: 121,086,027 (GRCm39)	A189V	probably benign	Het
Or10g9b	A	T	9: 39,918,038 (GRCm39)	M69K	possibly damaging	Het
Or12e9	T	A	2: 87,202,432 (GRCm39)	C185*	probably null	Het
Or4a68	A	G	2: 89,270,209 (GRCm39)	V138A	probably benign	Het
Or4c122	T	C	2: 89,079,034 (GRCm39)		probably null	Het
Or4c35	G	A	2: 89,808,497 (GRCm39)	C125Y	probably damaging	Het
Or51ai2	T	C	7: 103,586,710 (GRCm39)	V41A	probably benign	Het
Or52b4i	T	A	7: 102,191,587 (GRCm39)	V148E	possibly damaging	Het
Or5b111	A	T	19: 13,291,684 (GRCm39)		probably null	Het
Or7e165	T	G	9: 19,694,872 (GRCm39)	S148A	possibly damaging	Het
Or8b53	A	T	9: 38,667,703 (GRCm39)	T240S	probably damaging	Het
Orc3	A	T	4: 34,571,774 (GRCm39)	M665K	possibly damaging	Het
Pabpc1	A	G	15: 36,597,255 (GRCm39)	S591P	probably damaging	Het
Pacc1	A	T	1: 191,073,040 (GRCm39)	I154F	probably damaging	Het
Parp6	T	A	9: 59,531,645 (GRCm39)		probably null	Het
Pcdh1	T	C	18: 38,322,912 (GRCm39)	M974V	possibly damaging	Het
Pcdhb22	T	A	18: 37,653,713 (GRCm39)	V727E	possibly damaging	Het
Pex5l	T	C	3: 33,047,134 (GRCm39)	E272G	probably damaging	Het
Pglyrp2	G	T	17: 32,637,235 (GRCm39)	N264K	probably benign	Het
Phxr4	T	A	9: 13,342,882 (GRCm39)		probably benign	Het
Piezo2	A	G	18: 63,278,025 (GRCm39)	F293S	probably damaging	Het
Pkhd1	T	C	1: 20,607,625 (GRCm39)	D1077G	probably damaging	Het
Plekhs1	A	G	19: 56,461,700 (GRCm39)		probably null	Het
Prex1	G	T	2: 166,427,777 (GRCm39)	C788*	probably null	Het
Prrt3	A	T	6: 113,475,099 (GRCm39)	M41K	probably benign	Het
Ptgir	T	C	7: 16,642,768 (GRCm39)	V326A	probably damaging	Het
Ptprg	T	A	14: 12,220,654 (GRCm38)	D455E	probably damaging	Het
Ptpru	T	A	4: 131,526,914 (GRCm39)	Q686L	probably benign	Het
Pxdc1	G	T	13: 34,814,343 (GRCm39)	T190K	probably benign	Het
Rap1b	A	T	10: 117,654,487 (GRCm39)	C118S	probably benign	Het
Rapgef2	T	C	3: 78,990,534 (GRCm39)	M915V	probably benign	Het
Rnd2	C	T	11: 101,359,825 (GRCm39)	L57F	probably damaging	Het
Rpe65	C	T	3: 159,330,318 (GRCm39)	A495V	probably benign	Het
Samd15	A	G	12: 87,247,608 (GRCm39)	T98A	possibly damaging	Het
Sdk1	T	G	5: 141,568,049 (GRCm39)	D82E	probably benign	Het
Slc26a7	T	C	4: 14,546,309 (GRCm39)	D340G	probably benign	Het
Slc6a15	T	A	10: 103,253,921 (GRCm39)	M619K	probably benign	Het
Slc7a4	C	A	16: 17,392,385 (GRCm39)	D350Y	probably damaging	Het
Slk	T	G	19: 47,608,395 (GRCm39)	N449K	probably benign	Het
Spta1	A	T	1: 174,071,608 (GRCm39)		probably null	Het
Sptbn5	A	T	2: 119,886,374 (GRCm39)		probably benign	Het
Srd5a2	A	T	17: 74,354,800 (GRCm39)	V8D	probably benign	Het
Srgap3	G	A	6: 112,704,271 (GRCm39)	A906V	probably benign	Het
Stab2	A	T	10: 86,783,011 (GRCm39)	M679K	probably benign	Het
Stk3	T	C	15: 35,000,054 (GRCm39)	I291V	probably benign	Het
Supt6	T	A	11: 78,098,960 (GRCm39)	Q1637L	possibly damaging	Het
Svil	T	C	18: 5,114,564 (GRCm39)	F2047S	probably damaging	Het
Swsap1	A	G	9: 21,867,284 (GRCm39)	E76G	probably benign	Het
Syndig1	G	T	2: 149,741,473 (GRCm39)	G20C	probably damaging	Het
Synj2bp	A	T	12: 81,548,926 (GRCm39)	N104K	probably damaging	Het
Synpo2	T	A	3: 122,908,068 (GRCm39)	D416V	probably damaging	Het
Tacc3	G	T	5: 33,829,357 (GRCm39)	C620F	probably damaging	Het
Tanc1	A	G	2: 59,529,766 (GRCm39)	E19G	probably damaging	Het
Tars3	C	T	7: 65,297,302 (GRCm39)	A139V	probably benign	Het
Tbc1d22a	T	A	15: 86,235,935 (GRCm39)	C365S	probably damaging	Het
Tdpoz2	T	C	3: 93,559,381 (GRCm39)	H197R	possibly damaging	Het
Tha1	A	T	11: 117,760,205 (GRCm39)	N300K	probably damaging	Het
Tm6sf1	T	A	7: 81,515,008 (GRCm39)	F70L	probably damaging	Het
Tmem132b	T	A	5: 125,860,497 (GRCm39)	S581T	probably benign	Het
Tnfsf13	G	T	11: 69,576,075 (GRCm39)	S4*	probably null	Het
Tonsl	G	A	15: 76,517,448 (GRCm39)	S757L	probably benign	Het
Trem2	G	T	17: 48,658,719 (GRCm39)	R161S	possibly damaging	Het
Trpm2	A	T	10: 77,777,007 (GRCm39)	V430E	probably damaging	Het
Ttc14	T	A	3: 33,855,518 (GRCm39)	D154E	possibly damaging	Het
Ugt2b37	T	C	5: 87,398,498 (GRCm39)	M313V	possibly damaging	Het
Vmn2r24	A	G	6: 123,792,739 (GRCm39)	I689V	probably benign	Het
Wdr76	A	G	2: 121,372,975 (GRCm39)	T601A	probably benign	Het
Xirp1	T	C	9: 119,846,069 (GRCm39)	D938G	possibly damaging	Het
Zfp608	A	T	18: 55,031,041 (GRCm39)	D966E	probably benign	Het
Zfp957	A	G	14: 79,451,796 (GRCm39)	M1T	probably null	Het
Zkscan16	A	T	4: 58,957,809 (GRCm39)	H697L	possibly damaging	Het

Other mutations in Ehmt2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00973:Ehmt2	APN	17	35,129,791 (GRCm39)	missense	probably damaging	1.00
IGL02398:Ehmt2	APN	17	35,127,455 (GRCm39)	missense	probably damaging	1.00
IGL02878:Ehmt2	APN	17	35,129,743 (GRCm39)	missense	probably damaging	1.00
IGL02928:Ehmt2	APN	17	35,129,798 (GRCm39)	missense	probably damaging	1.00
IGL03117:Ehmt2	APN	17	35,125,787 (GRCm39)	missense	possibly damaging	0.54
R0630:Ehmt2	UTSW	17	35,118,818 (GRCm39)	missense	probably benign	0.02
R0778:Ehmt2	UTSW	17	35,124,394 (GRCm39)	missense	probably damaging	0.99
R0909:Ehmt2	UTSW	17	35,125,480 (GRCm39)	missense	possibly damaging	0.95
R1402:Ehmt2	UTSW	17	35,125,757 (GRCm39)	missense	probably benign	0.21
R1402:Ehmt2	UTSW	17	35,125,757 (GRCm39)	missense	probably benign	0.21
R1405:Ehmt2	UTSW	17	35,125,553 (GRCm39)	missense	probably benign
R1405:Ehmt2	UTSW	17	35,125,553 (GRCm39)	missense	probably benign
R1693:Ehmt2	UTSW	17	35,125,386 (GRCm39)	missense	possibly damaging	0.88
R1855:Ehmt2	UTSW	17	35,129,752 (GRCm39)	missense	probably damaging	1.00
R2212:Ehmt2	UTSW	17	35,118,341 (GRCm39)	missense	probably benign
R2275:Ehmt2	UTSW	17	35,129,691 (GRCm39)	missense	possibly damaging	0.95
R3761:Ehmt2	UTSW	17	35,132,707 (GRCm39)	missense	probably damaging	0.97
R3827:Ehmt2	UTSW	17	35,125,741 (GRCm39)	missense	possibly damaging	0.95
R3915:Ehmt2	UTSW	17	35,122,443 (GRCm39)	missense	probably damaging	0.99
R4303:Ehmt2	UTSW	17	35,127,724 (GRCm39)	missense	possibly damaging	0.92
R4529:Ehmt2	UTSW	17	35,132,707 (GRCm39)	missense	probably damaging	0.97
R4651:Ehmt2	UTSW	17	35,132,790 (GRCm39)	missense	probably damaging	1.00
R5061:Ehmt2	UTSW	17	35,118,067 (GRCm39)	nonsense	probably null
R5158:Ehmt2	UTSW	17	35,130,640 (GRCm39)	missense	probably damaging	1.00
R5298:Ehmt2	UTSW	17	35,118,067 (GRCm39)	nonsense	probably null
R5299:Ehmt2	UTSW	17	35,118,067 (GRCm39)	nonsense	probably null
R5523:Ehmt2	UTSW	17	35,118,067 (GRCm39)	nonsense	probably null
R5524:Ehmt2	UTSW	17	35,118,067 (GRCm39)	nonsense	probably null
R5727:Ehmt2	UTSW	17	35,125,008 (GRCm39)	missense	possibly damaging	0.75
R5755:Ehmt2	UTSW	17	35,127,214 (GRCm39)	missense	probably benign	0.05
R5786:Ehmt2	UTSW	17	35,129,719 (GRCm39)	missense	probably damaging	1.00
R5951:Ehmt2	UTSW	17	35,118,357 (GRCm39)	missense	probably benign
R6036:Ehmt2	UTSW	17	35,118,067 (GRCm39)	nonsense	probably null
R6162:Ehmt2	UTSW	17	35,118,067 (GRCm39)	nonsense	probably null
R6708:Ehmt2	UTSW	17	35,118,875 (GRCm39)	nonsense	probably null
R6889:Ehmt2	UTSW	17	35,131,748 (GRCm39)	missense	probably damaging	1.00
R6943:Ehmt2	UTSW	17	35,130,406 (GRCm39)	missense	probably damaging	1.00
R7470:Ehmt2	UTSW	17	35,118,372 (GRCm39)	missense	possibly damaging	0.67
R8061:Ehmt2	UTSW	17	35,124,903 (GRCm39)	missense	possibly damaging	0.66
R8095:Ehmt2	UTSW	17	35,126,745 (GRCm39)	missense	probably damaging	1.00
R8169:Ehmt2	UTSW	17	35,122,339 (GRCm39)	missense	probably benign
R8175:Ehmt2	UTSW	17	35,130,396 (GRCm39)	missense	probably damaging	1.00
R8244:Ehmt2	UTSW	17	35,124,238 (GRCm39)	missense	probably damaging	1.00
R8350:Ehmt2	UTSW	17	35,127,667 (GRCm39)	missense	probably damaging	1.00
R8357:Ehmt2	UTSW	17	35,124,137 (GRCm39)	small deletion	probably benign
R8809:Ehmt2	UTSW	17	35,127,489 (GRCm39)	missense	probably damaging	1.00
R8947:Ehmt2	UTSW	17	35,127,280 (GRCm39)	missense	possibly damaging	0.72
R9034:Ehmt2	UTSW	17	35,122,417 (GRCm39)	missense	probably benign	0.00
R9594:Ehmt2	UTSW	17	35,118,740 (GRCm39)	missense	possibly damaging	0.77

Predicted Primers

PCR Primer
(F):5'- CACTGACTCTGCCTAATGGG -3'
(R):5'- GCTTATAAGTTGTGCACTGGATC -3'

Sequencing Primer
(F):5'- TAATGGGGGCTGCCTCTC -3'
(R):5'- ACTGGATCAGTGCCCATTAC -3'

Posted On

2016-03-01