Incidental Mutation 'R4838:St18'
| ID |
371480 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
St18
|
| Ensembl Gene |
ENSMUSG00000033740 |
| Gene Name |
suppression of tumorigenicity 18 |
| Synonyms |
Nzf3, Myt3 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4838 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
6487231-6860940 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 6802905 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Lysine
at position 288
(T288K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131417
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043578]
[ENSMUST00000131494]
[ENSMUST00000139838]
[ENSMUST00000140079]
[ENSMUST00000150761]
[ENSMUST00000151281]
[ENSMUST00000163727]
|
| AlphaFold |
Q80TY4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043578
AA Change: T288K
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000042056
Gene: ENSMUSG00000033740
AA Change: T288K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131494
AA Change: T288K
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000117789
Gene: ENSMUSG00000033740
AA Change: T288K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000132207
AA Change: T38K
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139838
|
| SMART Domains |
Protein: ENSMUSP00000118129
Gene: ENSMUSG00000033740
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140079
AA Change: T288K
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000118322
Gene: ENSMUSG00000033740
AA Change: T288K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150761
AA Change: T288K
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000120298
Gene: ENSMUSG00000033740
AA Change: T288K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151281
AA Change: T288K
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000122055
Gene: ENSMUSG00000033740
AA Change: T288K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163727
AA Change: T288K
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000131417
Gene: ENSMUSG00000033740
AA Change: T288K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9530077C05Rik |
A |
T |
9: 22,424,377 (GRCm38) |
D97V |
probably damaging |
Het |
| Abca15 |
T |
C |
7: 120,345,300 (GRCm38) |
V386A |
probably benign |
Het |
| Adk |
G |
A |
14: 21,369,086 (GRCm38) |
A247T |
probably damaging |
Het |
| Ankrd27 |
T |
A |
7: 35,591,806 (GRCm38) |
L9Q |
possibly damaging |
Het |
| Atad2 |
A |
G |
15: 58,103,283 (GRCm38) |
L638P |
probably damaging |
Het |
| Atf7ip |
T |
A |
6: 136,596,491 (GRCm38) |
D1009E |
probably benign |
Het |
| Bend7 |
A |
T |
2: 4,744,322 (GRCm38) |
K83N |
probably damaging |
Het |
| Bicc1 |
C |
T |
10: 70,945,316 (GRCm38) |
D562N |
possibly damaging |
Het |
| Calcrl |
T |
A |
2: 84,351,205 (GRCm38) |
N200Y |
probably damaging |
Het |
| Ccdc125 |
C |
A |
13: 100,677,945 (GRCm38) |
A11E |
possibly damaging |
Het |
| Cd5l |
A |
G |
3: 87,365,951 (GRCm38) |
T76A |
probably benign |
Het |
| Cdhr5 |
A |
T |
7: 141,273,731 (GRCm38) |
I2N |
probably damaging |
Het |
| Cdk10 |
C |
T |
8: 123,230,614 (GRCm38) |
A230V |
probably damaging |
Het |
| Cep128 |
T |
C |
12: 90,999,545 (GRCm38) |
|
probably benign |
Het |
| Cep131 |
T |
C |
11: 120,076,156 (GRCm38) |
N186D |
probably damaging |
Het |
| Cog7 |
G |
T |
7: 121,971,381 (GRCm38) |
P168Q |
probably damaging |
Het |
| Col28a1 |
T |
A |
6: 8,014,559 (GRCm38) |
M949L |
probably benign |
Het |
| Coq8b |
T |
A |
7: 27,250,591 (GRCm38) |
M365K |
probably damaging |
Het |
| Cpa1 |
A |
G |
6: 30,639,516 (GRCm38) |
E18G |
possibly damaging |
Het |
| Csmd2 |
A |
G |
4: 128,517,749 (GRCm38) |
H2520R |
probably benign |
Het |
| Cyp2c69 |
T |
C |
19: 39,877,594 (GRCm38) |
N185S |
probably benign |
Het |
| Dpm1 |
G |
A |
2: 168,210,536 (GRCm38) |
T260I |
probably damaging |
Het |
| Dtx3 |
A |
T |
10: 127,191,307 (GRCm38) |
|
probably null |
Het |
| Eepd1 |
T |
C |
9: 25,589,460 (GRCm38) |
V401A |
possibly damaging |
Het |
| Ehhadh |
A |
G |
16: 21,763,202 (GRCm38) |
S347P |
possibly damaging |
Het |
| Elp3 |
A |
G |
14: 65,547,864 (GRCm38) |
|
probably null |
Het |
| Enam |
C |
T |
5: 88,493,108 (GRCm38) |
Q210* |
probably null |
Het |
| Epha1 |
C |
T |
6: 42,363,816 (GRCm38) |
R607H |
probably benign |
Het |
| Erich6 |
A |
G |
3: 58,636,830 (GRCm38) |
I112T |
probably benign |
Het |
| F830045P16Rik |
A |
G |
2: 129,460,550 (GRCm38) |
V374A |
possibly damaging |
Het |
| Fam171a2 |
C |
A |
11: 102,438,685 (GRCm38) |
R416L |
possibly damaging |
Het |
| Fam35a |
A |
G |
14: 34,268,625 (GRCm38) |
V108A |
probably benign |
Het |
| Fbn1 |
T |
C |
2: 125,372,399 (GRCm38) |
N764S |
probably benign |
Het |
| Fip1l1 |
C |
T |
5: 74,591,939 (GRCm38) |
T469I |
probably damaging |
Het |
| Flad1 |
G |
A |
3: 89,405,910 (GRCm38) |
R342C |
probably damaging |
Het |
| Fzd3 |
A |
G |
14: 65,239,820 (GRCm38) |
V95A |
probably benign |
Het |
| Garem1 |
T |
C |
18: 21,147,893 (GRCm38) |
T469A |
probably benign |
Het |
| Gm13084 |
G |
A |
4: 143,810,805 (GRCm38) |
Q319* |
probably null |
Het |
| Gm17093 |
A |
G |
14: 44,518,348 (GRCm38) |
Y24C |
unknown |
Het |
| Gm4788 |
T |
A |
1: 139,733,443 (GRCm38) |
D556V |
probably damaging |
Het |
| Gm7534 |
A |
G |
4: 134,193,099 (GRCm38) |
V585A |
probably benign |
Het |
| Grap2 |
T |
C |
15: 80,638,561 (GRCm38) |
V96A |
possibly damaging |
Het |
| Greb1 |
A |
T |
12: 16,684,360 (GRCm38) |
|
probably null |
Het |
| Grid2ip |
A |
T |
5: 143,388,775 (GRCm38) |
K913* |
probably null |
Het |
| Gzmk |
T |
C |
13: 113,173,021 (GRCm38) |
D126G |
probably damaging |
Het |
| Hibch |
A |
G |
1: 52,885,178 (GRCm38) |
I171V |
possibly damaging |
Het |
| Hipk2 |
G |
T |
6: 38,818,404 (GRCm38) |
T310K |
possibly damaging |
Het |
| Hk3 |
T |
C |
13: 55,006,418 (GRCm38) |
Y815C |
probably damaging |
Het |
| Hps5 |
A |
T |
7: 46,788,354 (GRCm38) |
V99E |
probably damaging |
Het |
| Hspg2 |
A |
G |
4: 137,541,666 (GRCm38) |
H2203R |
possibly damaging |
Het |
| Il12rb2 |
A |
G |
6: 67,309,137 (GRCm38) |
V108A |
probably damaging |
Het |
| Il6st |
C |
T |
13: 112,490,510 (GRCm38) |
R279* |
probably null |
Het |
| Kdm2a |
A |
C |
19: 4,325,026 (GRCm38) |
S692R |
probably benign |
Het |
| Kif13a |
T |
C |
13: 46,826,748 (GRCm38) |
K176R |
probably damaging |
Het |
| Kif5b |
T |
C |
18: 6,216,869 (GRCm38) |
K485E |
probably damaging |
Het |
| Ktn1 |
C |
T |
14: 47,725,956 (GRCm38) |
R1111* |
probably null |
Het |
| Lrrc23 |
A |
T |
6: 124,778,189 (GRCm38) |
N128K |
probably benign |
Het |
| Mad1l1 |
G |
A |
5: 140,300,262 (GRCm38) |
Q293* |
probably null |
Het |
| Man1b1 |
A |
T |
2: 25,345,475 (GRCm38) |
I338F |
possibly damaging |
Het |
| March1 |
G |
T |
8: 66,468,363 (GRCm38) |
V225L |
probably damaging |
Het |
| Mrpl3 |
A |
G |
9: 105,057,032 (GRCm38) |
D118G |
probably damaging |
Het |
| Nomo1 |
A |
T |
7: 46,083,715 (GRCm38) |
Q1209L |
unknown |
Het |
| Nrcam |
A |
G |
12: 44,574,019 (GRCm38) |
E949G |
probably damaging |
Het |
| Olfm5 |
T |
G |
7: 104,154,365 (GRCm38) |
N297T |
probably damaging |
Het |
| Olfr573-ps1 |
T |
A |
7: 102,942,246 (GRCm38) |
L110F |
probably damaging |
Het |
| Pcdh7 |
A |
T |
5: 57,720,804 (GRCm38) |
N567I |
probably damaging |
Het |
| Pkn1 |
A |
G |
8: 83,677,966 (GRCm38) |
L495P |
probably damaging |
Het |
| Pkp1 |
T |
C |
1: 135,882,588 (GRCm38) |
S415G |
probably damaging |
Het |
| Pou2f1 |
T |
A |
1: 165,916,923 (GRCm38) |
Q53L |
probably null |
Het |
| Prkce |
A |
G |
17: 86,630,083 (GRCm38) |
K648R |
probably benign |
Het |
| Ptprh |
G |
A |
7: 4,573,430 (GRCm38) |
T277I |
possibly damaging |
Het |
| Rpl31 |
C |
T |
1: 39,370,967 (GRCm38) |
R83C |
probably benign |
Het |
| Rpusd3 |
G |
A |
6: 113,416,876 (GRCm38) |
Q194* |
probably null |
Het |
| Sgsm1 |
T |
A |
5: 113,282,626 (GRCm38) |
N298Y |
probably damaging |
Het |
| She |
G |
A |
3: 89,851,639 (GRCm38) |
G355D |
probably benign |
Het |
| Snx11 |
C |
T |
11: 96,774,458 (GRCm38) |
E9K |
possibly damaging |
Het |
| Soat1 |
C |
A |
1: 156,432,937 (GRCm38) |
A444S |
probably benign |
Het |
| Sox6 |
T |
C |
7: 115,486,662 (GRCm38) |
Y690C |
probably damaging |
Het |
| Spata13 |
T |
A |
14: 60,733,179 (GRCm38) |
F10I |
probably benign |
Het |
| Tifa |
C |
T |
3: 127,796,586 (GRCm38) |
S2F |
probably damaging |
Het |
| Tmem232 |
A |
T |
17: 65,430,888 (GRCm38) |
S392R |
probably benign |
Het |
| Tmtc3 |
T |
C |
10: 100,466,220 (GRCm38) |
N289S |
probably damaging |
Het |
| Tpo |
A |
G |
12: 30,092,634 (GRCm38) |
F697S |
probably damaging |
Het |
| Trp53 |
A |
G |
11: 69,587,630 (GRCm38) |
T122A |
probably damaging |
Het |
| Trps1 |
A |
C |
15: 50,827,316 (GRCm38) |
I10S |
probably benign |
Het |
| Tubgcp5 |
C |
T |
7: 55,794,185 (GRCm38) |
|
probably benign |
Het |
| Unc13c |
T |
G |
9: 73,932,072 (GRCm38) |
Y499S |
possibly damaging |
Het |
| Unc45a |
C |
A |
7: 80,333,035 (GRCm38) |
D381Y |
probably damaging |
Het |
| Upf1 |
G |
C |
8: 70,339,368 (GRCm38) |
H402Q |
probably benign |
Het |
| Uroc1 |
A |
T |
6: 90,349,192 (GRCm38) |
I510F |
possibly damaging |
Het |
| Usp15 |
A |
G |
10: 123,127,757 (GRCm38) |
F589L |
probably damaging |
Het |
| Vmn2r76 |
T |
C |
7: 86,225,525 (GRCm38) |
Y748C |
probably damaging |
Het |
| Wwp1 |
T |
C |
4: 19,662,143 (GRCm38) |
N151D |
probably benign |
Het |
| Zbtb40 |
A |
T |
4: 137,001,216 (GRCm38) |
S439T |
probably benign |
Het |
| Zbtb6 |
A |
T |
2: 37,428,716 (GRCm38) |
L400* |
probably null |
Het |
| Zfp125 |
C |
T |
12: 20,899,960 (GRCm38) |
|
noncoding transcript |
Het |
| Zmynd8 |
A |
C |
2: 165,840,034 (GRCm38) |
Y183* |
probably null |
Het |
|
| Other mutations in St18 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:St18
|
APN |
1 |
6,802,572 (GRCm38) |
missense |
probably benign |
0.07 |
|
IGL00840:St18
|
APN |
1 |
6,833,594 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01016:St18
|
APN |
1 |
6,844,323 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01116:St18
|
APN |
1 |
6,802,632 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01719:St18
|
APN |
1 |
6,845,796 (GRCm38) |
splice site |
probably benign |
|
|
IGL01885:St18
|
APN |
1 |
6,844,372 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02486:St18
|
APN |
1 |
6,820,083 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02611:St18
|
APN |
1 |
6,768,890 (GRCm38) |
splice site |
probably benign |
|
|
IGL02742:St18
|
APN |
1 |
6,802,316 (GRCm38) |
splice site |
probably benign |
|
|
IGL02953:St18
|
APN |
1 |
6,844,113 (GRCm38) |
splice site |
probably benign |
|
|
IGL02999:St18
|
APN |
1 |
6,817,605 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03092:St18
|
APN |
1 |
6,768,894 (GRCm38) |
splice site |
probably benign |
|
|
Smallish
|
UTSW |
1 |
6,855,473 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL03055:St18
|
UTSW |
1 |
6,802,735 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0089:St18
|
UTSW |
1 |
6,848,948 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0257:St18
|
UTSW |
1 |
6,819,962 (GRCm38) |
missense |
probably benign |
0.04 |
|
R0383:St18
|
UTSW |
1 |
6,803,024 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0588:St18
|
UTSW |
1 |
6,817,738 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0989:St18
|
UTSW |
1 |
6,827,881 (GRCm38) |
missense |
probably benign |
0.04 |
|
R1068:St18
|
UTSW |
1 |
6,795,562 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1311:St18
|
UTSW |
1 |
6,845,644 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1530:St18
|
UTSW |
1 |
6,845,569 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R1723:St18
|
UTSW |
1 |
6,810,685 (GRCm38) |
splice site |
probably benign |
|
|
R1926:St18
|
UTSW |
1 |
6,802,689 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1927:St18
|
UTSW |
1 |
6,802,712 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2035:St18
|
UTSW |
1 |
6,802,328 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2091:St18
|
UTSW |
1 |
6,827,971 (GRCm38) |
missense |
probably benign |
0.08 |
|
R2139:St18
|
UTSW |
1 |
6,810,615 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R2261:St18
|
UTSW |
1 |
6,845,572 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R2300:St18
|
UTSW |
1 |
6,855,402 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2322:St18
|
UTSW |
1 |
6,844,124 (GRCm38) |
nonsense |
probably null |
|
|
R2846:St18
|
UTSW |
1 |
6,845,587 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3738:St18
|
UTSW |
1 |
6,855,473 (GRCm38) |
critical splice donor site |
probably null |
|
|
R3739:St18
|
UTSW |
1 |
6,855,473 (GRCm38) |
critical splice donor site |
probably null |
|
|
R3772:St18
|
UTSW |
1 |
6,844,329 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3805:St18
|
UTSW |
1 |
6,802,353 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:St18
|
UTSW |
1 |
6,802,893 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4034:St18
|
UTSW |
1 |
6,855,473 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4036:St18
|
UTSW |
1 |
6,827,786 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4407:St18
|
UTSW |
1 |
6,827,837 (GRCm38) |
missense |
probably benign |
0.29 |
|
R4527:St18
|
UTSW |
1 |
6,855,423 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4740:St18
|
UTSW |
1 |
6,817,604 (GRCm38) |
missense |
probably benign |
|
|
R5182:St18
|
UTSW |
1 |
6,817,653 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5186:St18
|
UTSW |
1 |
6,802,317 (GRCm38) |
splice site |
probably null |
|
|
R5354:St18
|
UTSW |
1 |
6,844,171 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5423:St18
|
UTSW |
1 |
6,802,616 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5724:St18
|
UTSW |
1 |
6,770,950 (GRCm38) |
missense |
probably benign |
0.13 |
|
R6182:St18
|
UTSW |
1 |
6,844,118 (GRCm38) |
splice site |
probably null |
|
|
R6491:St18
|
UTSW |
1 |
6,827,985 (GRCm38) |
nonsense |
probably null |
|
|
R6503:St18
|
UTSW |
1 |
6,795,397 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7037:St18
|
UTSW |
1 |
6,803,036 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R7098:St18
|
UTSW |
1 |
6,827,842 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7132:St18
|
UTSW |
1 |
6,859,127 (GRCm38) |
missense |
|
|
|
R7144:St18
|
UTSW |
1 |
6,833,594 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7150:St18
|
UTSW |
1 |
6,803,019 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7334:St18
|
UTSW |
1 |
6,802,559 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7502:St18
|
UTSW |
1 |
6,827,970 (GRCm38) |
missense |
probably benign |
0.09 |
|
R7729:St18
|
UTSW |
1 |
6,802,537 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7848:St18
|
UTSW |
1 |
6,857,445 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8088:St18
|
UTSW |
1 |
6,828,005 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8299:St18
|
UTSW |
1 |
6,802,992 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8338:St18
|
UTSW |
1 |
6,809,292 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8690:St18
|
UTSW |
1 |
6,802,564 (GRCm38) |
missense |
probably benign |
|
|
R8753:St18
|
UTSW |
1 |
6,845,791 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8808:St18
|
UTSW |
1 |
6,810,602 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8880:St18
|
UTSW |
1 |
6,795,395 (GRCm38) |
nonsense |
probably null |
|
|
R9055:St18
|
UTSW |
1 |
6,802,982 (GRCm38) |
nonsense |
probably null |
|
|
R9292:St18
|
UTSW |
1 |
6,827,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R9322:St18
|
UTSW |
1 |
6,795,523 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9530:St18
|
UTSW |
1 |
6,802,773 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9603:St18
|
UTSW |
1 |
6,845,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9611:St18
|
UTSW |
1 |
6,802,923 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9639:St18
|
UTSW |
1 |
6,859,022 (GRCm38) |
missense |
|
|
|
R9644:St18
|
UTSW |
1 |
6,859,052 (GRCm38) |
missense |
|
|
|
R9740:St18
|
UTSW |
1 |
6,803,063 (GRCm38) |
nonsense |
probably null |
|
|
R9750:St18
|
UTSW |
1 |
6,802,992 (GRCm38) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGCTCCAACTCATCAGAAG -3'
(R):5'- ATCAGTAACTCTAGGTTGCCTCC -3'
Sequencing Primer
(F):5'- AAGGACCTGTTGGAAGTTCC -3'
(R):5'- CGTTCCCTTGCCAGGTG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation