Incidental Mutation 'R4840:Chd1'
| ID |
371779 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chd1
|
| Ensembl Gene |
ENSMUSG00000023852 |
| Gene Name |
chromodomain helicase DNA binding protein 1 |
| Synonyms |
4930525N21Rik |
| MMRRC Submission |
042453-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4840 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
15704967-15772610 bp(+) (GRCm38) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to A
at 15768753 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tryptophan to Stop codon
at position 1589
(W1589*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000024627
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000024627]
|
| AlphaFold |
P40201 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000024627
AA Change: W1589*
|
| SMART Domains |
Protein: ENSMUSP00000024627
Gene: ENSMUSG00000023852
AA Change: W1589*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
67 |
N/A |
INTRINSIC |
|
low complexity region
|
105 |
115 |
N/A |
INTRINSIC |
|
low complexity region
|
116 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
175 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
230 |
N/A |
INTRINSIC |
|
CHROMO
|
268 |
355 |
6.43e-20 |
SMART |
|
CHROMO
|
385 |
443 |
1.19e-14 |
SMART |
|
DEXDc
|
475 |
672 |
3.44e-34 |
SMART |
|
Blast:DEXDc
|
692 |
786 |
2e-54 |
BLAST |
|
low complexity region
|
787 |
799 |
N/A |
INTRINSIC |
|
HELICc
|
816 |
900 |
8.48e-25 |
SMART |
|
Blast:DEXDc
|
955 |
1234 |
1e-112 |
BLAST |
|
PDB:4B4C|A
|
1119 |
1320 |
1e-132 |
PDB |
|
low complexity region
|
1325 |
1348 |
N/A |
INTRINSIC |
|
low complexity region
|
1377 |
1388 |
N/A |
INTRINSIC |
|
DUF4208
|
1396 |
1500 |
5.54e-51 |
SMART |
|
low complexity region
|
1507 |
1516 |
N/A |
INTRINSIC |
|
low complexity region
|
1538 |
1549 |
N/A |
INTRINSIC |
|
low complexity region
|
1626 |
1650 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.1%
|
| Validation Efficiency |
97% (114/117) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality associated with arrest of epiblast development due to increased apoptosis and cell cycle defects, abnormal rostral-caudal axis patterning, and failure to gastrulate. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810459M11Rik |
C |
A |
1: 86,046,444 (GRCm38) |
T161K |
probably benign |
Het |
| Actn3 |
G |
A |
19: 4,864,511 (GRCm38) |
R530W |
probably damaging |
Het |
| Alg11 |
C |
T |
8: 22,068,010 (GRCm38) |
A404V |
possibly damaging |
Het |
| Alkbh8 |
T |
A |
9: 3,369,751 (GRCm38) |
V340D |
probably damaging |
Het |
| Arhgef12 |
T |
C |
9: 42,975,068 (GRCm38) |
H1166R |
probably benign |
Het |
| Aspm |
T |
A |
1: 139,470,531 (GRCm38) |
D978E |
possibly damaging |
Het |
| Bod1l |
C |
T |
5: 41,818,472 (GRCm38) |
G1833D |
probably damaging |
Het |
| Brd3 |
A |
G |
2: 27,449,239 (GRCm38) |
V676A |
possibly damaging |
Het |
| Brip1 |
G |
A |
11: 86,146,183 (GRCm38) |
T454I |
possibly damaging |
Het |
| C3ar1 |
T |
C |
6: 122,850,764 (GRCm38) |
I165V |
probably benign |
Het |
| C87977 |
T |
C |
4: 144,208,574 (GRCm38) |
K199R |
probably damaging |
Het |
| Camta1 |
T |
A |
4: 151,144,407 (GRCm38) |
Q656L |
probably benign |
Het |
| Casp14 |
A |
T |
10: 78,713,344 (GRCm38) |
L256* |
probably null |
Het |
| Cdh23 |
G |
T |
10: 60,419,777 (GRCm38) |
H773Q |
possibly damaging |
Het |
| Cldn19 |
A |
G |
4: 119,255,754 (GRCm38) |
Q61R |
probably damaging |
Het |
| Cyp2a22 |
A |
G |
7: 26,932,524 (GRCm38) |
S436P |
probably benign |
Het |
| E130218I03Rik |
A |
G |
4: 134,245,276 (GRCm38) |
|
probably benign |
Het |
| Emc10 |
A |
C |
7: 44,492,627 (GRCm38) |
V124G |
probably damaging |
Het |
| Enam |
A |
T |
5: 88,503,026 (GRCm38) |
D723V |
probably benign |
Het |
| Eps8 |
C |
A |
6: 137,527,130 (GRCm38) |
Q158H |
probably damaging |
Het |
| Ercc6 |
G |
A |
14: 32,541,296 (GRCm38) |
D486N |
probably damaging |
Het |
| Fasn |
T |
C |
11: 120,813,059 (GRCm38) |
E1485G |
possibly damaging |
Het |
| Fat2 |
T |
C |
11: 55,279,018 (GRCm38) |
K2972E |
probably benign |
Het |
| Fbxw28 |
T |
C |
9: 109,339,534 (GRCm38) |
K30R |
probably null |
Het |
| Flot2 |
T |
A |
11: 78,057,513 (GRCm38) |
L164Q |
probably damaging |
Het |
| Fsip2 |
A |
T |
2: 82,949,395 (GRCm38) |
I162L |
probably benign |
Het |
| Fsip2 |
A |
T |
2: 82,985,471 (GRCm38) |
L3849F |
probably benign |
Het |
| Gabrb1 |
C |
G |
5: 71,700,811 (GRCm38) |
P60R |
probably damaging |
Het |
| Galnt14 |
T |
C |
17: 73,504,898 (GRCm38) |
R443G |
probably benign |
Het |
| Gas8 |
C |
T |
8: 123,531,014 (GRCm38) |
T400M |
probably benign |
Het |
| Gfap |
T |
C |
11: 102,894,388 (GRCm38) |
Y254C |
probably damaging |
Het |
| Git2 |
A |
G |
5: 114,745,482 (GRCm38) |
S396P |
probably damaging |
Het |
| Glb1l3 |
A |
T |
9: 26,829,053 (GRCm38) |
M327K |
probably benign |
Het |
| Gm10715 |
A |
C |
9: 3,038,062 (GRCm38) |
|
probably benign |
Het |
| Gm10787 |
G |
A |
10: 77,022,007 (GRCm38) |
|
noncoding transcript |
Het |
| Gm1123 |
T |
A |
9: 99,018,569 (GRCm38) |
D78V |
probably damaging |
Het |
| Gm27013 |
T |
C |
6: 130,678,116 (GRCm38) |
T128A |
probably benign |
Het |
| Gm8979 |
T |
C |
7: 106,081,420 (GRCm38) |
|
noncoding transcript |
Het |
| Gpbp1 |
A |
G |
13: 111,440,630 (GRCm38) |
|
probably null |
Het |
| Gphn |
G |
A |
12: 78,522,955 (GRCm38) |
|
probably null |
Het |
| Gpr157 |
A |
G |
4: 150,102,366 (GRCm38) |
E317G |
probably benign |
Het |
| Gsdmc4 |
T |
A |
15: 63,893,747 (GRCm38) |
M318L |
probably benign |
Het |
| Gtf2f2 |
A |
T |
14: 76,010,691 (GRCm38) |
W19R |
probably damaging |
Het |
| Helb |
A |
G |
10: 120,084,858 (GRCm38) |
V1060A |
probably benign |
Het |
| Igfn1 |
C |
T |
1: 135,968,040 (GRCm38) |
G1596D |
probably benign |
Het |
| Il1rl2 |
T |
C |
1: 40,327,387 (GRCm38) |
I27T |
possibly damaging |
Het |
| Inpp5j |
A |
G |
11: 3,499,676 (GRCm38) |
V702A |
probably damaging |
Het |
| Kmt2d |
A |
C |
15: 98,861,894 (GRCm38) |
V1161G |
unknown |
Het |
| Krtap1-3 |
T |
G |
11: 99,590,889 (GRCm38) |
Y144S |
possibly damaging |
Het |
| Layn |
C |
T |
9: 51,057,382 (GRCm38) |
V354M |
probably damaging |
Het |
| Lrba |
G |
A |
3: 86,619,509 (GRCm38) |
|
probably null |
Het |
| Lrp8 |
T |
A |
4: 107,870,037 (GRCm38) |
L893Q |
possibly damaging |
Het |
| Mrps9 |
T |
A |
1: 42,898,415 (GRCm38) |
|
probably benign |
Het |
| Mug1 |
T |
A |
6: 121,885,854 (GRCm38) |
M1387K |
probably damaging |
Het |
| Myo18b |
A |
C |
5: 112,874,029 (GRCm38) |
V499G |
probably benign |
Het |
| Nbea |
T |
C |
3: 55,710,670 (GRCm38) |
E2321G |
probably benign |
Het |
| Nrsn2 |
C |
T |
2: 152,369,632 (GRCm38) |
V160I |
probably benign |
Het |
| Nup210 |
G |
A |
6: 91,031,668 (GRCm38) |
Q510* |
probably null |
Het |
| Ofcc1 |
G |
A |
13: 40,015,388 (GRCm38) |
T841I |
probably damaging |
Het |
| Olfr693 |
T |
G |
7: 106,678,123 (GRCm38) |
D121A |
probably damaging |
Het |
| P3h3 |
G |
T |
6: 124,850,637 (GRCm38) |
Q479K |
possibly damaging |
Het |
| Paqr9 |
T |
A |
9: 95,560,670 (GRCm38) |
F238I |
probably damaging |
Het |
| Parp3 |
A |
T |
9: 106,473,109 (GRCm38) |
L343H |
probably damaging |
Het |
| Pcdh18 |
A |
C |
3: 49,744,668 (GRCm38) |
M1115R |
probably damaging |
Het |
| Pcdh8 |
A |
G |
14: 79,770,868 (GRCm38) |
V85A |
possibly damaging |
Het |
| Pcdhb4 |
A |
G |
18: 37,308,399 (GRCm38) |
N254S |
possibly damaging |
Het |
| Pld1 |
T |
C |
3: 28,076,551 (GRCm38) |
V500A |
probably benign |
Het |
| Prkg2 |
A |
T |
5: 98,981,143 (GRCm38) |
D311E |
probably benign |
Het |
| Prss42 |
T |
C |
9: 110,799,301 (GRCm38) |
L171P |
probably damaging |
Het |
| Pth2 |
T |
A |
7: 45,181,343 (GRCm38) |
L17H |
probably damaging |
Het |
| Reln |
A |
T |
5: 22,018,846 (GRCm38) |
|
probably null |
Het |
| Rmi2 |
G |
T |
16: 10,839,837 (GRCm38) |
V104L |
probably damaging |
Het |
| Rpusd4 |
T |
A |
9: 35,268,535 (GRCm38) |
V108D |
probably damaging |
Het |
| Rufy4 |
C |
A |
1: 74,129,039 (GRCm38) |
T82K |
possibly damaging |
Het |
| Scimp |
G |
A |
11: 70,791,468 (GRCm38) |
Q141* |
probably null |
Het |
| Sel1l2 |
T |
C |
2: 140,263,470 (GRCm38) |
T267A |
probably benign |
Het |
| Sema5a |
T |
A |
15: 32,550,254 (GRCm38) |
S146R |
possibly damaging |
Het |
| Sh2d3c |
T |
C |
2: 32,721,160 (GRCm38) |
M1T |
probably null |
Het |
| Slc30a6 |
T |
C |
17: 74,405,721 (GRCm38) |
L71P |
probably damaging |
Het |
| Srrm3 |
A |
G |
5: 135,854,595 (GRCm38) |
Y224C |
possibly damaging |
Het |
| Tacr3 |
A |
T |
3: 134,854,854 (GRCm38) |
T185S |
possibly damaging |
Het |
| Tas2r140 |
T |
A |
6: 133,055,565 (GRCm38) |
T77S |
probably benign |
Het |
| Thsd7b |
T |
C |
1: 129,595,844 (GRCm38) |
V128A |
probably benign |
Het |
| Tnfrsf10b |
T |
G |
14: 69,776,159 (GRCm38) |
H179Q |
probably damaging |
Het |
| Tonsl |
A |
G |
15: 76,633,209 (GRCm38) |
V770A |
probably benign |
Het |
| Trim42 |
G |
A |
9: 97,362,929 (GRCm38) |
P606L |
probably benign |
Het |
| Trim45 |
A |
T |
3: 100,925,488 (GRCm38) |
T346S |
possibly damaging |
Het |
| Ttc28 |
C |
A |
5: 111,286,081 (GRCm38) |
S2296Y |
probably damaging |
Het |
| Ttc41 |
C |
T |
10: 86,731,125 (GRCm38) |
R552C |
probably benign |
Het |
| Tube1 |
A |
G |
10: 39,144,846 (GRCm38) |
N243D |
probably benign |
Het |
| Tvp23b |
G |
T |
11: 62,879,598 (GRCm38) |
|
probably null |
Het |
| Ubxn11 |
T |
A |
4: 134,109,608 (GRCm38) |
I49N |
probably damaging |
Het |
| Usp17le |
T |
A |
7: 104,769,770 (GRCm38) |
E55V |
probably benign |
Het |
| Vmn2r114 |
A |
T |
17: 23,291,379 (GRCm38) |
V709D |
probably damaging |
Het |
| Vmn2r23 |
C |
T |
6: 123,713,074 (GRCm38) |
T303M |
probably damaging |
Het |
| Vmn2r60 |
C |
T |
7: 42,135,861 (GRCm38) |
P166S |
probably damaging |
Het |
| Vmn2r83 |
A |
G |
10: 79,477,848 (GRCm38) |
I97V |
possibly damaging |
Het |
| Vmn2r-ps159 |
G |
C |
4: 156,333,438 (GRCm38) |
|
noncoding transcript |
Het |
| Wbp2nl |
A |
T |
15: 82,314,336 (GRCm38) |
K358M |
possibly damaging |
Het |
| Xpo1 |
T |
A |
11: 23,278,183 (GRCm38) |
I150N |
probably damaging |
Het |
| Zfp113 |
G |
A |
5: 138,145,425 (GRCm38) |
L188F |
probably damaging |
Het |
| Zfp189 |
T |
G |
4: 49,529,984 (GRCm38) |
S362R |
probably damaging |
Het |
|
| Other mutations in Chd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00704:Chd1
|
APN |
17 |
15,732,565 (GRCm38) |
missense |
probably benign |
0.37 |
|
IGL01356:Chd1
|
APN |
17 |
15,749,865 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01369:Chd1
|
APN |
17 |
15,754,997 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL01519:Chd1
|
APN |
17 |
17,378,569 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01604:Chd1
|
APN |
17 |
15,770,097 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL01635:Chd1
|
APN |
17 |
17,378,596 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01721:Chd1
|
APN |
17 |
15,770,168 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01959:Chd1
|
APN |
17 |
15,742,173 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02367:Chd1
|
APN |
17 |
17,390,053 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02476:Chd1
|
APN |
17 |
15,734,273 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02756:Chd1
|
APN |
17 |
15,730,807 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02817:Chd1
|
APN |
17 |
15,749,500 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL03084:Chd1
|
APN |
17 |
15,770,298 (GRCm38) |
missense |
probably benign |
0.22 |
|
IGL03108:Chd1
|
APN |
17 |
15,725,281 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
Holly
|
UTSW |
17 |
15,726,283 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R0053:Chd1
|
UTSW |
17 |
15,747,189 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0053:Chd1
|
UTSW |
17 |
15,747,189 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0128:Chd1
|
UTSW |
17 |
17,393,567 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0197:Chd1
|
UTSW |
17 |
15,725,431 (GRCm38) |
missense |
probably benign |
|
|
R0285:Chd1
|
UTSW |
17 |
17,374,680 (GRCm38) |
splice site |
probably benign |
|
|
R0326:Chd1
|
UTSW |
17 |
15,768,568 (GRCm38) |
missense |
probably benign |
|
|
R0326:Chd1
|
UTSW |
17 |
15,768,566 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0372:Chd1
|
UTSW |
17 |
17,387,290 (GRCm38) |
missense |
probably benign |
0.14 |
|
R0391:Chd1
|
UTSW |
17 |
15,749,894 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0486:Chd1
|
UTSW |
17 |
15,734,342 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0637:Chd1
|
UTSW |
17 |
15,742,288 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R0675:Chd1
|
UTSW |
17 |
15,758,261 (GRCm38) |
unclassified |
probably benign |
|
|
R0701:Chd1
|
UTSW |
17 |
15,725,431 (GRCm38) |
missense |
probably benign |
|
|
R0788:Chd1
|
UTSW |
17 |
15,707,114 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R0848:Chd1
|
UTSW |
17 |
15,770,241 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0883:Chd1
|
UTSW |
17 |
15,725,431 (GRCm38) |
missense |
probably benign |
|
|
R1169:Chd1
|
UTSW |
17 |
15,735,732 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1218:Chd1
|
UTSW |
17 |
15,725,312 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1370:Chd1
|
UTSW |
17 |
17,387,480 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1470:Chd1
|
UTSW |
17 |
15,726,283 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R1470:Chd1
|
UTSW |
17 |
15,726,283 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R1478:Chd1
|
UTSW |
17 |
15,739,507 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1752:Chd1
|
UTSW |
17 |
15,743,232 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1759:Chd1
|
UTSW |
17 |
17,387,271 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1767:Chd1
|
UTSW |
17 |
15,770,303 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Chd1
|
UTSW |
17 |
15,762,486 (GRCm38) |
missense |
probably benign |
0.39 |
|
R2007:Chd1
|
UTSW |
17 |
15,731,006 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2069:Chd1
|
UTSW |
17 |
15,742,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3771:Chd1
|
UTSW |
17 |
17,374,651 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3773:Chd1
|
UTSW |
17 |
17,374,651 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3849:Chd1
|
UTSW |
17 |
15,731,871 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4241:Chd1
|
UTSW |
17 |
15,770,027 (GRCm38) |
nonsense |
probably null |
|
|
R4242:Chd1
|
UTSW |
17 |
15,770,027 (GRCm38) |
nonsense |
probably null |
|
|
R4354:Chd1
|
UTSW |
17 |
17,390,001 (GRCm38) |
missense |
probably benign |
0.23 |
|
R4468:Chd1
|
UTSW |
17 |
15,760,395 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4469:Chd1
|
UTSW |
17 |
15,760,395 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4731:Chd1
|
UTSW |
17 |
17,377,817 (GRCm38) |
missense |
probably benign |
0.36 |
|
R4824:Chd1
|
UTSW |
17 |
15,733,124 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4840:Chd1
|
UTSW |
17 |
15,768,754 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4880:Chd1
|
UTSW |
17 |
17,374,654 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4960:Chd1
|
UTSW |
17 |
15,742,231 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5071:Chd1
|
UTSW |
17 |
15,762,405 (GRCm38) |
missense |
probably benign |
|
|
R5078:Chd1
|
UTSW |
17 |
15,726,354 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R5114:Chd1
|
UTSW |
17 |
15,728,198 (GRCm38) |
missense |
probably benign |
0.25 |
|
R5268:Chd1
|
UTSW |
17 |
15,735,743 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5304:Chd1
|
UTSW |
17 |
15,770,268 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R5304:Chd1
|
UTSW |
17 |
15,754,951 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5307:Chd1
|
UTSW |
17 |
15,732,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5458:Chd1
|
UTSW |
17 |
15,738,549 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5553:Chd1
|
UTSW |
17 |
17,385,613 (GRCm38) |
missense |
probably benign |
0.17 |
|
R5623:Chd1
|
UTSW |
17 |
15,754,932 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6022:Chd1
|
UTSW |
17 |
17,377,773 (GRCm38) |
missense |
probably benign |
0.39 |
|
R6137:Chd1
|
UTSW |
17 |
15,758,688 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6257:Chd1
|
UTSW |
17 |
15,730,203 (GRCm38) |
splice site |
probably null |
|
|
R6373:Chd1
|
UTSW |
17 |
15,738,636 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6458:Chd1
|
UTSW |
17 |
15,730,602 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6476:Chd1
|
UTSW |
17 |
17,380,988 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6508:Chd1
|
UTSW |
17 |
15,738,633 (GRCm38) |
missense |
probably benign |
0.31 |
|
R6553:Chd1
|
UTSW |
17 |
15,725,430 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6745:Chd1
|
UTSW |
17 |
17,387,167 (GRCm38) |
missense |
probably benign |
0.08 |
|
R7107:Chd1
|
UTSW |
17 |
15,761,366 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7230:Chd1
|
UTSW |
17 |
15,706,937 (GRCm38) |
splice site |
probably null |
|
|
R7317:Chd1
|
UTSW |
17 |
15,742,274 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R7341:Chd1
|
UTSW |
17 |
15,770,237 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7421:Chd1
|
UTSW |
17 |
15,749,398 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7704:Chd1
|
UTSW |
17 |
15,767,475 (GRCm38) |
missense |
probably benign |
|
|
R7763:Chd1
|
UTSW |
17 |
15,733,041 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8156:Chd1
|
UTSW |
17 |
15,761,404 (GRCm38) |
missense |
probably benign |
|
|
R8194:Chd1
|
UTSW |
17 |
17,374,475 (GRCm38) |
start gained |
probably benign |
|
|
R8261:Chd1
|
UTSW |
17 |
17,387,542 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8338:Chd1
|
UTSW |
17 |
15,769,980 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8401:Chd1
|
UTSW |
17 |
15,743,211 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8411:Chd1
|
UTSW |
17 |
15,762,449 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9067:Chd1
|
UTSW |
17 |
15,730,845 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R9184:Chd1
|
UTSW |
17 |
15,742,289 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R9210:Chd1
|
UTSW |
17 |
15,730,505 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R9212:Chd1
|
UTSW |
17 |
15,730,505 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R9666:Chd1
|
UTSW |
17 |
15,735,714 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9673:Chd1
|
UTSW |
17 |
15,768,761 (GRCm38) |
missense |
probably benign |
0.24 |
|
Z1176:Chd1
|
UTSW |
17 |
15,768,733 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Chd1
|
UTSW |
17 |
15,766,347 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Z1177:Chd1
|
UTSW |
17 |
15,747,801 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGGGCAGGAGTTACTGTTATTA -3'
(R):5'- TTCCACCAACAAGCTGCACT -3'
Sequencing Primer
(F):5'- AGTAGCAGGGACAGCTAT -3'
(R):5'- CCAACAAGCTGCACTATTTAAAATG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation