Incidental Mutation 'R4831:Cfap65'
| ID |
372779 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cfap65
|
| Ensembl Gene |
ENSMUSG00000047021 |
| Gene Name |
cilia and flagella associated protein 65 |
| Synonyms |
Ccdc108, B230363K08Rik |
| MMRRC Submission |
042447-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.676)
|
| Stock # |
R4831 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
74902071-74935599 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 74917295 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Phenylalanine
at position 1042
(V1042F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000092440
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094844]
|
| AlphaFold |
Q3V0B4 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000094844
AA Change: V1042F
PolyPhen 2
Score 0.927 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000092440
Gene: ENSMUSG00000047021
AA Change: V1042F
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
111 |
133 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
745 |
890 |
9.31e-5 |
PROSPERO |
|
internal_repeat_1
|
1167 |
1322 |
9.31e-5 |
PROSPERO |
|
low complexity region
|
1350 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1574 |
1592 |
N/A |
INTRINSIC |
|
coiled coil region
|
1687 |
1724 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.3%
|
| Validation Efficiency |
99% (96/97) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene has putative coiled-coil domains and may be a transmembrane protein. The chicken ortholog of this gene is involved in the Rose-comb mutation, which is a large chromosome inversion, resulting in altered comb morphology and defects in sperm motility. [provided by RefSeq, Aug 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810408A11Rik |
C |
T |
11: 69,900,577 (GRCm38) |
V59I |
possibly damaging |
Het |
| 4930544M13Rik |
T |
G |
13: 114,607,647 (GRCm38) |
|
noncoding transcript |
Het |
| Abca13 |
A |
T |
11: 9,542,077 (GRCm38) |
K4373* |
probably null |
Het |
| Abtb2 |
A |
T |
2: 103,683,475 (GRCm38) |
T410S |
probably benign |
Het |
| Adamts13 |
T |
C |
2: 26,983,130 (GRCm38) |
|
probably null |
Het |
| Ahnak2 |
C |
G |
12: 112,775,749 (GRCm38) |
D630H |
probably damaging |
Het |
| Aox3 |
T |
C |
1: 58,152,566 (GRCm38) |
S426P |
probably damaging |
Het |
| Atxn10 |
C |
T |
15: 85,387,059 (GRCm38) |
S266F |
probably benign |
Het |
| B4galnt4 |
T |
A |
7: 141,064,557 (GRCm38) |
|
probably null |
Het |
| B4galnt4 |
G |
T |
7: 141,067,721 (GRCm38) |
M407I |
probably damaging |
Het |
| Bclaf1 |
T |
A |
10: 20,322,126 (GRCm38) |
|
probably benign |
Het |
| C4b |
C |
T |
17: 34,736,890 (GRCm38) |
|
probably null |
Het |
| Cdc42bpg |
T |
C |
19: 6,311,335 (GRCm38) |
F297S |
probably damaging |
Het |
| Cdh10 |
A |
T |
15: 19,013,578 (GRCm38) |
T755S |
probably benign |
Het |
| Ceacam12 |
T |
A |
7: 18,077,380 (GRCm38) |
|
probably null |
Het |
| Cfap77 |
T |
C |
2: 28,985,832 (GRCm38) |
I89V |
probably benign |
Het |
| Cfh |
T |
C |
1: 140,086,387 (GRCm38) |
D688G |
probably benign |
Het |
| Clip1 |
C |
G |
5: 123,583,601 (GRCm38) |
A1182P |
probably damaging |
Het |
| Cyp2b10 |
T |
A |
7: 25,915,496 (GRCm38) |
Y309* |
probably null |
Het |
| Dcaf5 |
T |
C |
12: 80,339,084 (GRCm38) |
E756G |
probably benign |
Het |
| Dctn1 |
A |
T |
6: 83,199,771 (GRCm38) |
Q1231L |
possibly damaging |
Het |
| Dennd1c |
T |
A |
17: 57,066,428 (GRCm38) |
R682* |
probably null |
Het |
| Eml6 |
C |
A |
11: 29,777,052 (GRCm38) |
E1319* |
probably null |
Het |
| Erap1 |
T |
C |
13: 74,690,647 (GRCm38) |
I904T |
probably damaging |
Het |
| Eri1 |
A |
T |
8: 35,476,519 (GRCm38) |
I207N |
possibly damaging |
Het |
| Farp1 |
G |
A |
14: 121,277,057 (GRCm38) |
A933T |
probably damaging |
Het |
| Fcna |
T |
A |
2: 25,625,341 (GRCm38) |
Q210L |
probably benign |
Het |
| Fhad1 |
A |
T |
4: 141,916,067 (GRCm38) |
|
probably null |
Het |
| Fut8 |
T |
G |
12: 77,393,829 (GRCm38) |
Y197D |
probably damaging |
Het |
| Garem1 |
G |
A |
18: 21,129,768 (GRCm38) |
T663I |
probably benign |
Het |
| Gfm2 |
T |
C |
13: 97,165,038 (GRCm38) |
S450P |
probably damaging |
Het |
| Gstk1 |
T |
G |
6: 42,246,004 (GRCm38) |
|
probably benign |
Het |
| Helz2 |
C |
T |
2: 181,237,417 (GRCm38) |
A803T |
probably damaging |
Het |
| Igsf9 |
T |
A |
1: 172,491,888 (GRCm38) |
I280N |
probably damaging |
Het |
| Klhl10 |
A |
G |
11: 100,445,843 (GRCm38) |
K219E |
probably benign |
Het |
| L3mbtl4 |
T |
A |
17: 68,461,563 (GRCm38) |
V222D |
probably damaging |
Het |
| Lrrc9 |
A |
T |
12: 72,499,679 (GRCm38) |
N1214Y |
probably damaging |
Het |
| Ltbp2 |
C |
T |
12: 84,793,640 (GRCm38) |
E1051K |
possibly damaging |
Het |
| Mettl17 |
T |
C |
14: 51,884,983 (GRCm38) |
F13S |
probably benign |
Het |
| Mettl24 |
C |
A |
10: 40,683,417 (GRCm38) |
A21D |
possibly damaging |
Het |
| Mfsd6l |
T |
A |
11: 68,556,505 (GRCm38) |
C61S |
probably benign |
Het |
| Mob4 |
T |
G |
1: 55,152,740 (GRCm38) |
D204E |
probably benign |
Het |
| Mtus1 |
C |
G |
8: 41,083,152 (GRCm38) |
R509T |
probably damaging |
Het |
| Nlrp4a |
T |
A |
7: 26,450,419 (GRCm38) |
F484I |
possibly damaging |
Het |
| Nsrp1 |
T |
C |
11: 77,050,618 (GRCm38) |
N88S |
probably benign |
Het |
| Odad2 |
G |
T |
18: 7,222,564 (GRCm38) |
H568Q |
possibly damaging |
Het |
| Or10d5 |
C |
T |
9: 39,950,112 (GRCm38) |
V220I |
probably benign |
Het |
| Or2g25 |
T |
A |
17: 37,660,078 (GRCm38) |
H85L |
probably benign |
Het |
| Or51b6b |
T |
C |
7: 103,660,471 (GRCm38) |
T260A |
probably benign |
Het |
| Or6c2 |
T |
A |
10: 129,526,580 (GRCm38) |
Y118N |
probably damaging |
Het |
| Parg |
A |
G |
14: 32,202,451 (GRCm38) |
N69S |
probably benign |
Het |
| Pcdh9 |
A |
C |
14: 93,887,941 (GRCm38) |
N264K |
probably damaging |
Het |
| Pcdhb22 |
G |
T |
18: 37,520,562 (GRCm38) |
L694F |
probably damaging |
Het |
| Pcnt |
T |
C |
10: 76,412,501 (GRCm38) |
E928G |
probably damaging |
Het |
| Pdzk1 |
G |
A |
3: 96,868,435 (GRCm38) |
G373D |
probably benign |
Het |
| Pea15a |
A |
G |
1: 172,199,173 (GRCm38) |
I89T |
probably damaging |
Het |
| Phc1 |
T |
A |
6: 122,337,005 (GRCm38) |
|
probably benign |
Het |
| Pikfyve |
T |
A |
1: 65,196,741 (GRCm38) |
C191S |
probably damaging |
Het |
| Pitpnm1 |
T |
A |
19: 4,108,130 (GRCm38) |
D573E |
probably damaging |
Het |
| Pld5 |
A |
G |
1: 176,274,884 (GRCm38) |
|
probably benign |
Het |
| Plscr2 |
A |
T |
9: 92,291,077 (GRCm38) |
N89I |
possibly damaging |
Het |
| Pm20d2 |
A |
C |
4: 33,179,293 (GRCm38) |
N315K |
probably damaging |
Het |
| Pnpla1 |
T |
A |
17: 28,878,544 (GRCm38) |
M228K |
probably benign |
Het |
| Prim2 |
T |
C |
1: 33,670,136 (GRCm38) |
|
probably benign |
Het |
| Ralgapa2 |
A |
G |
2: 146,405,067 (GRCm38) |
|
probably benign |
Het |
| Rgs22 |
G |
T |
15: 36,050,148 (GRCm38) |
H719N |
probably benign |
Het |
| Ror2 |
C |
T |
13: 53,118,844 (GRCm38) |
D250N |
probably damaging |
Het |
| Saal1 |
A |
G |
7: 46,699,647 (GRCm38) |
V281A |
probably benign |
Het |
| Selenof |
A |
T |
3: 144,590,650 (GRCm38) |
K94N |
probably damaging |
Het |
| Slamf9 |
T |
A |
1: 172,477,264 (GRCm38) |
C148* |
probably null |
Het |
| Slc4a7 |
T |
C |
14: 14,772,699 (GRCm38) |
|
probably null |
Het |
| Slco1a5 |
A |
G |
6: 142,234,705 (GRCm38) |
I657T |
probably benign |
Het |
| St3gal2 |
A |
T |
8: 110,957,848 (GRCm38) |
H46L |
probably benign |
Het |
| Sucnr1 |
T |
G |
3: 60,086,648 (GRCm38) |
M199R |
probably damaging |
Het |
| Taok1 |
T |
A |
11: 77,553,674 (GRCm38) |
E525V |
probably null |
Het |
| Tbc1d10c |
T |
A |
19: 4,185,446 (GRCm38) |
E298V |
probably damaging |
Het |
| Tll2 |
T |
A |
19: 41,130,512 (GRCm38) |
H259L |
probably damaging |
Het |
| Tpcn1 |
A |
T |
5: 120,553,489 (GRCm38) |
F300Y |
probably damaging |
Het |
| Uba6 |
T |
A |
5: 86,131,338 (GRCm38) |
I642L |
probably benign |
Het |
| Ubqln5 |
T |
A |
7: 104,129,622 (GRCm38) |
|
probably benign |
Het |
| Vmn1r27 |
A |
T |
6: 58,215,842 (GRCm38) |
L9Q |
possibly damaging |
Het |
| Vmn2r100 |
C |
T |
17: 19,521,410 (GRCm38) |
T128I |
probably benign |
Het |
| Vmn2r109 |
C |
T |
17: 20,541,232 (GRCm38) |
G621D |
probably benign |
Het |
| Vmn2r49 |
C |
T |
7: 9,986,425 (GRCm38) |
D380N |
probably benign |
Het |
| Vps13a |
C |
T |
19: 16,677,992 (GRCm38) |
V1891I |
probably benign |
Het |
| Wbp2 |
G |
T |
11: 116,080,637 (GRCm38) |
Y147* |
probably null |
Het |
| Wdr46 |
T |
A |
17: 33,941,836 (GRCm38) |
N191K |
probably benign |
Het |
| Wdr46 |
T |
C |
17: 33,949,399 (GRCm38) |
|
probably benign |
Het |
| Wnt2 |
A |
C |
6: 18,023,286 (GRCm38) |
F121L |
probably benign |
Het |
| Xpnpep1 |
T |
A |
19: 53,014,622 (GRCm38) |
D100V |
probably benign |
Het |
| Xpo4 |
T |
C |
14: 57,590,102 (GRCm38) |
Y879C |
probably damaging |
Het |
| Zswim4 |
A |
T |
8: 84,212,319 (GRCm38) |
V978D |
probably damaging |
Het |
|
| Other mutations in Cfap65 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01107:Cfap65
|
APN |
1 |
74,919,183 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01526:Cfap65
|
APN |
1 |
74,911,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01716:Cfap65
|
APN |
1 |
74,927,194 (GRCm38) |
missense |
probably benign |
|
|
IGL01780:Cfap65
|
APN |
1 |
74,928,348 (GRCm38) |
nonsense |
probably null |
|
|
IGL01993:Cfap65
|
APN |
1 |
74,920,543 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02164:Cfap65
|
APN |
1 |
74,928,145 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
IGL02350:Cfap65
|
APN |
1 |
74,928,348 (GRCm38) |
nonsense |
probably null |
|
|
IGL02357:Cfap65
|
APN |
1 |
74,928,348 (GRCm38) |
nonsense |
probably null |
|
|
IGL02576:Cfap65
|
APN |
1 |
74,903,458 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02756:Cfap65
|
APN |
1 |
74,905,080 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02792:Cfap65
|
APN |
1 |
74,927,178 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02874:Cfap65
|
APN |
1 |
74,911,108 (GRCm38) |
nonsense |
probably null |
|
|
IGL03101:Cfap65
|
APN |
1 |
74,928,433 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
IGL03348:Cfap65
|
APN |
1 |
74,927,619 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03396:Cfap65
|
APN |
1 |
74,904,642 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4131001:Cfap65
|
UTSW |
1 |
74,928,342 (GRCm38) |
missense |
probably benign |
0.05 |
|
R0077:Cfap65
|
UTSW |
1 |
74,931,918 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0227:Cfap65
|
UTSW |
1 |
74,931,958 (GRCm38) |
nonsense |
probably null |
|
|
R0281:Cfap65
|
UTSW |
1 |
74,927,071 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0312:Cfap65
|
UTSW |
1 |
74,904,067 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,929,302 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,929,301 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0347:Cfap65
|
UTSW |
1 |
74,926,444 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0359:Cfap65
|
UTSW |
1 |
74,920,601 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0361:Cfap65
|
UTSW |
1 |
74,925,440 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0465:Cfap65
|
UTSW |
1 |
74,916,884 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0549:Cfap65
|
UTSW |
1 |
74,918,444 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0646:Cfap65
|
UTSW |
1 |
74,902,169 (GRCm38) |
missense |
probably benign |
0.09 |
|
R0734:Cfap65
|
UTSW |
1 |
74,918,887 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0763:Cfap65
|
UTSW |
1 |
74,904,682 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0990:Cfap65
|
UTSW |
1 |
74,921,519 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R1079:Cfap65
|
UTSW |
1 |
74,905,713 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1079:Cfap65
|
UTSW |
1 |
74,902,447 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1083:Cfap65
|
UTSW |
1 |
74,918,504 (GRCm38) |
splice site |
probably benign |
|
|
R1159:Cfap65
|
UTSW |
1 |
74,929,340 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1282:Cfap65
|
UTSW |
1 |
74,925,104 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1644:Cfap65
|
UTSW |
1 |
74,917,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1796:Cfap65
|
UTSW |
1 |
74,918,948 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1950:Cfap65
|
UTSW |
1 |
74,907,660 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2079:Cfap65
|
UTSW |
1 |
74,917,199 (GRCm38) |
missense |
probably benign |
0.30 |
|
R2132:Cfap65
|
UTSW |
1 |
74,907,691 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2136:Cfap65
|
UTSW |
1 |
74,917,273 (GRCm38) |
frame shift |
probably null |
|
|
R2219:Cfap65
|
UTSW |
1 |
74,904,025 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2220:Cfap65
|
UTSW |
1 |
74,904,025 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2291:Cfap65
|
UTSW |
1 |
74,926,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2417:Cfap65
|
UTSW |
1 |
74,927,186 (GRCm38) |
small insertion |
probably benign |
|
|
R3114:Cfap65
|
UTSW |
1 |
74,927,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4202:Cfap65
|
UTSW |
1 |
74,920,542 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4214:Cfap65
|
UTSW |
1 |
74,927,681 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R4254:Cfap65
|
UTSW |
1 |
74,903,358 (GRCm38) |
missense |
probably benign |
0.17 |
|
R4547:Cfap65
|
UTSW |
1 |
74,907,612 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4548:Cfap65
|
UTSW |
1 |
74,907,612 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4588:Cfap65
|
UTSW |
1 |
74,904,056 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4657:Cfap65
|
UTSW |
1 |
74,925,354 (GRCm38) |
intron |
probably benign |
|
|
R4701:Cfap65
|
UTSW |
1 |
74,918,908 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4755:Cfap65
|
UTSW |
1 |
74,928,361 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4820:Cfap65
|
UTSW |
1 |
74,927,632 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4866:Cfap65
|
UTSW |
1 |
74,925,557 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4869:Cfap65
|
UTSW |
1 |
74,919,261 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4881:Cfap65
|
UTSW |
1 |
74,907,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4884:Cfap65
|
UTSW |
1 |
74,903,124 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R4950:Cfap65
|
UTSW |
1 |
74,906,336 (GRCm38) |
nonsense |
probably null |
|
|
R5074:Cfap65
|
UTSW |
1 |
74,922,978 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5083:Cfap65
|
UTSW |
1 |
74,906,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5164:Cfap65
|
UTSW |
1 |
74,926,516 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5268:Cfap65
|
UTSW |
1 |
74,924,902 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5333:Cfap65
|
UTSW |
1 |
74,903,175 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5417:Cfap65
|
UTSW |
1 |
74,925,100 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5582:Cfap65
|
UTSW |
1 |
74,907,518 (GRCm38) |
intron |
probably benign |
|
|
R5669:Cfap65
|
UTSW |
1 |
74,924,968 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6010:Cfap65
|
UTSW |
1 |
74,923,031 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6084:Cfap65
|
UTSW |
1 |
74,920,405 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6112:Cfap65
|
UTSW |
1 |
74,903,139 (GRCm38) |
missense |
probably benign |
0.14 |
|
R6425:Cfap65
|
UTSW |
1 |
74,927,709 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6677:Cfap65
|
UTSW |
1 |
74,904,685 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6693:Cfap65
|
UTSW |
1 |
74,917,286 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6838:Cfap65
|
UTSW |
1 |
74,932,021 (GRCm38) |
missense |
probably benign |
0.06 |
|
R6861:Cfap65
|
UTSW |
1 |
74,925,115 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6958:Cfap65
|
UTSW |
1 |
74,931,899 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R7134:Cfap65
|
UTSW |
1 |
74,926,633 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7320:Cfap65
|
UTSW |
1 |
74,926,604 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7340:Cfap65
|
UTSW |
1 |
74,921,583 (GRCm38) |
missense |
probably benign |
0.07 |
|
R7426:Cfap65
|
UTSW |
1 |
74,920,426 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R7529:Cfap65
|
UTSW |
1 |
74,926,610 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7634:Cfap65
|
UTSW |
1 |
74,902,434 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7654:Cfap65
|
UTSW |
1 |
74,933,144 (GRCm38) |
missense |
probably benign |
0.44 |
|
R7704:Cfap65
|
UTSW |
1 |
74,928,368 (GRCm38) |
missense |
probably benign |
0.19 |
|
R7727:Cfap65
|
UTSW |
1 |
74,926,625 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7895:Cfap65
|
UTSW |
1 |
74,933,162 (GRCm38) |
missense |
probably benign |
0.05 |
|
R8215:Cfap65
|
UTSW |
1 |
74,910,743 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8344:Cfap65
|
UTSW |
1 |
74,928,044 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8345:Cfap65
|
UTSW |
1 |
74,928,044 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8413:Cfap65
|
UTSW |
1 |
74,917,169 (GRCm38) |
nonsense |
probably null |
|
|
R8431:Cfap65
|
UTSW |
1 |
74,928,044 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8432:Cfap65
|
UTSW |
1 |
74,928,044 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8528:Cfap65
|
UTSW |
1 |
74,905,937 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R8809:Cfap65
|
UTSW |
1 |
74,903,223 (GRCm38) |
missense |
probably benign |
0.43 |
|
R8996:Cfap65
|
UTSW |
1 |
74,902,188 (GRCm38) |
missense |
probably benign |
0.11 |
|
R9020:Cfap65
|
UTSW |
1 |
74,920,393 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9043:Cfap65
|
UTSW |
1 |
74,904,688 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R9127:Cfap65
|
UTSW |
1 |
74,919,351 (GRCm38) |
splice site |
probably benign |
|
|
R9187:Cfap65
|
UTSW |
1 |
74,917,358 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9210:Cfap65
|
UTSW |
1 |
74,920,408 (GRCm38) |
missense |
probably benign |
|
|
R9212:Cfap65
|
UTSW |
1 |
74,920,408 (GRCm38) |
missense |
probably benign |
|
|
R9273:Cfap65
|
UTSW |
1 |
74,921,610 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9454:Cfap65
|
UTSW |
1 |
74,905,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9514:Cfap65
|
UTSW |
1 |
74,906,309 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9595:Cfap65
|
UTSW |
1 |
74,907,378 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9721:Cfap65
|
UTSW |
1 |
74,919,342 (GRCm38) |
missense |
probably benign |
0.16 |
|
R9742:Cfap65
|
UTSW |
1 |
74,904,681 (GRCm38) |
missense |
probably benign |
0.08 |
|
RF009:Cfap65
|
UTSW |
1 |
74,905,647 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Cfap65
|
UTSW |
1 |
74,910,747 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCTTCTTGGGAAAGGCCTG -3'
(R):5'- CTGCCATTGGAAATATGCTCAAG -3'
Sequencing Primer
(F):5'- TGTGAGCCTCCCGTGTTGC -3'
(R):5'- TATGCTCAAGATTGAAGCTGAGCC -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation