Incidental Mutation 'R4831:Nlrp4a'
| ID |
372808 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrp4a
|
| Ensembl Gene |
ENSMUSG00000040601 |
| Gene Name |
NLR family, pyrin domain containing 4A |
| Synonyms |
E330028A19Rik, Nalp-eta, Nalp4a |
| MMRRC Submission |
042447-MU
|
| Accession Numbers |
Genbank: NM_172896; MGI: 2443697
|
| Essential gene? |
Probably non essential
(E-score: 0.090)
|
| Stock # |
R4831 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
26435113-26476142 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 26450419 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Isoleucine
at position 484
(F484I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000146044
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068767]
[ENSMUST00000119386]
[ENSMUST00000146907]
|
| AlphaFold |
Q8BU40 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000068767
AA Change: F484I
PolyPhen 2
Score 0.822 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000066841
Gene: ENSMUSG00000040601
AA Change: F484I
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
6 |
89 |
6.48e-34 |
SMART |
|
Pfam:NACHT
|
148 |
317 |
4.9e-37 |
PFAM |
|
Blast:LRR
|
634 |
661 |
4e-6 |
BLAST |
|
low complexity region
|
666 |
677 |
N/A |
INTRINSIC |
|
LRR
|
689 |
716 |
5.96e0 |
SMART |
|
LRR
|
718 |
745 |
1.99e1 |
SMART |
|
LRR
|
746 |
772 |
1.02e0 |
SMART |
|
LRR
|
774 |
801 |
4.66e1 |
SMART |
|
LRR
|
802 |
829 |
1.18e-2 |
SMART |
|
LRR
|
831 |
858 |
2.2e-2 |
SMART |
|
LRR
|
859 |
886 |
5.59e-4 |
SMART |
|
LRR
|
888 |
915 |
9.41e0 |
SMART |
|
LRR
|
916 |
943 |
8.94e1 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000119386
AA Change: F484I
PolyPhen 2
Score 0.822 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000112441
Gene: ENSMUSG00000040601
AA Change: F484I
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
6 |
89 |
6.48e-34 |
SMART |
|
Pfam:NACHT
|
148 |
317 |
1.3e-37 |
PFAM |
|
Blast:LRR
|
634 |
661 |
4e-6 |
BLAST |
|
low complexity region
|
666 |
677 |
N/A |
INTRINSIC |
|
LRR
|
689 |
716 |
5.96e0 |
SMART |
|
LRR
|
718 |
745 |
1.99e1 |
SMART |
|
LRR
|
746 |
772 |
1.02e0 |
SMART |
|
LRR
|
774 |
801 |
4.66e1 |
SMART |
|
LRR
|
802 |
829 |
1.18e-2 |
SMART |
|
LRR
|
831 |
858 |
2.2e-2 |
SMART |
|
LRR
|
859 |
886 |
5.59e-4 |
SMART |
|
LRR
|
888 |
915 |
9.41e0 |
SMART |
|
LRR
|
916 |
943 |
8.94e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146534
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000146907
AA Change: F484I
PolyPhen 2
Score 0.918 (Sensitivity: 0.81; Specificity: 0.94)
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.3%
|
| Validation Efficiency |
99% (96/97) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810408A11Rik |
C |
T |
11: 69,900,577 (GRCm38) |
V59I |
possibly damaging |
Het |
| 4930544M13Rik |
T |
G |
13: 114,607,647 (GRCm38) |
|
noncoding transcript |
Het |
| Abca13 |
A |
T |
11: 9,542,077 (GRCm38) |
K4373* |
probably null |
Het |
| Abtb2 |
A |
T |
2: 103,683,475 (GRCm38) |
T410S |
probably benign |
Het |
| Adamts13 |
T |
C |
2: 26,983,130 (GRCm38) |
|
probably null |
Het |
| Ahnak2 |
C |
G |
12: 112,775,749 (GRCm38) |
D630H |
probably damaging |
Het |
| Aox3 |
T |
C |
1: 58,152,566 (GRCm38) |
S426P |
probably damaging |
Het |
| Armc4 |
G |
T |
18: 7,222,564 (GRCm38) |
H568Q |
possibly damaging |
Het |
| Atxn10 |
C |
T |
15: 85,387,059 (GRCm38) |
S266F |
probably benign |
Het |
| B4galnt4 |
T |
A |
7: 141,064,557 (GRCm38) |
|
probably null |
Het |
| B4galnt4 |
G |
T |
7: 141,067,721 (GRCm38) |
M407I |
probably damaging |
Het |
| Bclaf1 |
T |
A |
10: 20,322,126 (GRCm38) |
|
probably benign |
Het |
| C4b |
C |
T |
17: 34,736,890 (GRCm38) |
|
probably null |
Het |
| Cdc42bpg |
T |
C |
19: 6,311,335 (GRCm38) |
F297S |
probably damaging |
Het |
| Cdh10 |
A |
T |
15: 19,013,578 (GRCm38) |
T755S |
probably benign |
Het |
| Ceacam12 |
T |
A |
7: 18,077,380 (GRCm38) |
|
probably null |
Het |
| Cfap65 |
C |
A |
1: 74,917,295 (GRCm38) |
V1042F |
possibly damaging |
Het |
| Cfap77 |
T |
C |
2: 28,985,832 (GRCm38) |
I89V |
probably benign |
Het |
| Cfh |
T |
C |
1: 140,086,387 (GRCm38) |
D688G |
probably benign |
Het |
| Clip1 |
C |
G |
5: 123,583,601 (GRCm38) |
A1182P |
probably damaging |
Het |
| Cyp2b10 |
T |
A |
7: 25,915,496 (GRCm38) |
Y309* |
probably null |
Het |
| Dcaf5 |
T |
C |
12: 80,339,084 (GRCm38) |
E756G |
probably benign |
Het |
| Dctn1 |
A |
T |
6: 83,199,771 (GRCm38) |
Q1231L |
possibly damaging |
Het |
| Dennd1c |
T |
A |
17: 57,066,428 (GRCm38) |
R682* |
probably null |
Het |
| Eml6 |
C |
A |
11: 29,777,052 (GRCm38) |
E1319* |
probably null |
Het |
| Erap1 |
T |
C |
13: 74,690,647 (GRCm38) |
I904T |
probably damaging |
Het |
| Eri1 |
A |
T |
8: 35,476,519 (GRCm38) |
I207N |
possibly damaging |
Het |
| Farp1 |
G |
A |
14: 121,277,057 (GRCm38) |
A933T |
probably damaging |
Het |
| Fcna |
T |
A |
2: 25,625,341 (GRCm38) |
Q210L |
probably benign |
Het |
| Fhad1 |
A |
T |
4: 141,916,067 (GRCm38) |
|
probably null |
Het |
| Fut8 |
T |
G |
12: 77,393,829 (GRCm38) |
Y197D |
probably damaging |
Het |
| Garem1 |
G |
A |
18: 21,129,768 (GRCm38) |
T663I |
probably benign |
Het |
| Gfm2 |
T |
C |
13: 97,165,038 (GRCm38) |
S450P |
probably damaging |
Het |
| Gstk1 |
T |
G |
6: 42,246,004 (GRCm38) |
|
probably benign |
Het |
| Helz2 |
C |
T |
2: 181,237,417 (GRCm38) |
A803T |
probably damaging |
Het |
| Igsf9 |
T |
A |
1: 172,491,888 (GRCm38) |
I280N |
probably damaging |
Het |
| Klhl10 |
A |
G |
11: 100,445,843 (GRCm38) |
K219E |
probably benign |
Het |
| L3mbtl4 |
T |
A |
17: 68,461,563 (GRCm38) |
V222D |
probably damaging |
Het |
| Lrrc9 |
A |
T |
12: 72,499,679 (GRCm38) |
N1214Y |
probably damaging |
Het |
| Ltbp2 |
C |
T |
12: 84,793,640 (GRCm38) |
E1051K |
possibly damaging |
Het |
| Mettl17 |
T |
C |
14: 51,884,983 (GRCm38) |
F13S |
probably benign |
Het |
| Mettl24 |
C |
A |
10: 40,683,417 (GRCm38) |
A21D |
possibly damaging |
Het |
| Mfsd6l |
T |
A |
11: 68,556,505 (GRCm38) |
C61S |
probably benign |
Het |
| Mob4 |
T |
G |
1: 55,152,740 (GRCm38) |
D204E |
probably benign |
Het |
| Mtus1 |
C |
G |
8: 41,083,152 (GRCm38) |
R509T |
probably damaging |
Het |
| Nsrp1 |
T |
C |
11: 77,050,618 (GRCm38) |
N88S |
probably benign |
Het |
| Olfr117 |
T |
A |
17: 37,660,078 (GRCm38) |
H85L |
probably benign |
Het |
| Olfr623 |
T |
C |
7: 103,660,471 (GRCm38) |
T260A |
probably benign |
Het |
| Olfr791 |
T |
A |
10: 129,526,580 (GRCm38) |
Y118N |
probably damaging |
Het |
| Olfr975 |
C |
T |
9: 39,950,112 (GRCm38) |
V220I |
probably benign |
Het |
| Parg |
A |
G |
14: 32,202,451 (GRCm38) |
N69S |
probably benign |
Het |
| Pcdh9 |
A |
C |
14: 93,887,941 (GRCm38) |
N264K |
probably damaging |
Het |
| Pcdhb22 |
G |
T |
18: 37,520,562 (GRCm38) |
L694F |
probably damaging |
Het |
| Pcnt |
T |
C |
10: 76,412,501 (GRCm38) |
E928G |
probably damaging |
Het |
| Pdzk1 |
G |
A |
3: 96,868,435 (GRCm38) |
G373D |
probably benign |
Het |
| Pea15a |
A |
G |
1: 172,199,173 (GRCm38) |
I89T |
probably damaging |
Het |
| Phc1 |
T |
A |
6: 122,337,005 (GRCm38) |
|
probably benign |
Het |
| Pikfyve |
T |
A |
1: 65,196,741 (GRCm38) |
C191S |
probably damaging |
Het |
| Pitpnm1 |
T |
A |
19: 4,108,130 (GRCm38) |
D573E |
probably damaging |
Het |
| Pld5 |
A |
G |
1: 176,274,884 (GRCm38) |
|
probably benign |
Het |
| Plscr2 |
A |
T |
9: 92,291,077 (GRCm38) |
N89I |
possibly damaging |
Het |
| Pm20d2 |
A |
C |
4: 33,179,293 (GRCm38) |
N315K |
probably damaging |
Het |
| Pnpla1 |
T |
A |
17: 28,878,544 (GRCm38) |
M228K |
probably benign |
Het |
| Prim2 |
T |
C |
1: 33,670,136 (GRCm38) |
|
probably benign |
Het |
| Ralgapa2 |
A |
G |
2: 146,405,067 (GRCm38) |
|
probably benign |
Het |
| Rgs22 |
G |
T |
15: 36,050,148 (GRCm38) |
H719N |
probably benign |
Het |
| Ror2 |
C |
T |
13: 53,118,844 (GRCm38) |
D250N |
probably damaging |
Het |
| Saal1 |
A |
G |
7: 46,699,647 (GRCm38) |
V281A |
probably benign |
Het |
| Selenof |
A |
T |
3: 144,590,650 (GRCm38) |
K94N |
probably damaging |
Het |
| Slamf9 |
T |
A |
1: 172,477,264 (GRCm38) |
C148* |
probably null |
Het |
| Slc4a7 |
T |
C |
14: 14,772,699 (GRCm38) |
|
probably null |
Het |
| Slco1a5 |
A |
G |
6: 142,234,705 (GRCm38) |
I657T |
probably benign |
Het |
| St3gal2 |
A |
T |
8: 110,957,848 (GRCm38) |
H46L |
probably benign |
Het |
| Sucnr1 |
T |
G |
3: 60,086,648 (GRCm38) |
M199R |
probably damaging |
Het |
| Taok1 |
T |
A |
11: 77,553,674 (GRCm38) |
E525V |
probably null |
Het |
| Tbc1d10c |
T |
A |
19: 4,185,446 (GRCm38) |
E298V |
probably damaging |
Het |
| Tll2 |
T |
A |
19: 41,130,512 (GRCm38) |
H259L |
probably damaging |
Het |
| Tpcn1 |
A |
T |
5: 120,553,489 (GRCm38) |
F300Y |
probably damaging |
Het |
| Uba6 |
T |
A |
5: 86,131,338 (GRCm38) |
I642L |
probably benign |
Het |
| Ubqln5 |
T |
A |
7: 104,129,622 (GRCm38) |
|
probably benign |
Het |
| Vmn1r27 |
A |
T |
6: 58,215,842 (GRCm38) |
L9Q |
possibly damaging |
Het |
| Vmn2r100 |
C |
T |
17: 19,521,410 (GRCm38) |
T128I |
probably benign |
Het |
| Vmn2r109 |
C |
T |
17: 20,541,232 (GRCm38) |
G621D |
probably benign |
Het |
| Vmn2r49 |
C |
T |
7: 9,986,425 (GRCm38) |
D380N |
probably benign |
Het |
| Vps13a |
C |
T |
19: 16,677,992 (GRCm38) |
V1891I |
probably benign |
Het |
| Wbp2 |
G |
T |
11: 116,080,637 (GRCm38) |
Y147* |
probably null |
Het |
| Wdr46 |
T |
A |
17: 33,941,836 (GRCm38) |
N191K |
probably benign |
Het |
| Wdr46 |
T |
C |
17: 33,949,399 (GRCm38) |
|
probably benign |
Het |
| Wnt2 |
A |
C |
6: 18,023,286 (GRCm38) |
F121L |
probably benign |
Het |
| Xpnpep1 |
T |
A |
19: 53,014,622 (GRCm38) |
D100V |
probably benign |
Het |
| Xpo4 |
T |
C |
14: 57,590,102 (GRCm38) |
Y879C |
probably damaging |
Het |
| Zswim4 |
A |
T |
8: 84,212,319 (GRCm38) |
V978D |
probably damaging |
Het |
|
| Other mutations in Nlrp4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00487:Nlrp4a
|
APN |
7 |
26,449,985 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
IGL00972:Nlrp4a
|
APN |
7 |
26,457,048 (GRCm38) |
missense |
probably benign |
|
|
IGL01081:Nlrp4a
|
APN |
7 |
26,449,829 (GRCm38) |
missense |
probably benign |
0.06 |
|
IGL01788:Nlrp4a
|
APN |
7 |
26,454,067 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL02001:Nlrp4a
|
APN |
7 |
26,449,969 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02070:Nlrp4a
|
APN |
7 |
26,449,278 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
IGL02175:Nlrp4a
|
APN |
7 |
26,475,097 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02193:Nlrp4a
|
APN |
7 |
26,449,278 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
IGL02193:Nlrp4a
|
APN |
7 |
26,459,692 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02197:Nlrp4a
|
APN |
7 |
26,449,278 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
IGL02200:Nlrp4a
|
APN |
7 |
26,449,278 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
IGL02202:Nlrp4a
|
APN |
7 |
26,449,278 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
IGL02207:Nlrp4a
|
APN |
7 |
26,449,278 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
IGL02237:Nlrp4a
|
APN |
7 |
26,449,278 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
IGL02240:Nlrp4a
|
APN |
7 |
26,449,278 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
IGL02658:Nlrp4a
|
APN |
7 |
26,449,713 (GRCm38) |
missense |
probably benign |
0.43 |
|
IGL02743:Nlrp4a
|
APN |
7 |
26,459,815 (GRCm38) |
splice site |
probably benign |
|
|
IGL02960:Nlrp4a
|
APN |
7 |
26,449,730 (GRCm38) |
missense |
probably benign |
0.05 |
|
IGL03064:Nlrp4a
|
APN |
7 |
26,449,509 (GRCm38) |
missense |
probably benign |
0.23 |
|
IGL03276:Nlrp4a
|
APN |
7 |
26,464,190 (GRCm38) |
missense |
probably damaging |
1.00 |
|
BB002:Nlrp4a
|
UTSW |
7 |
26,450,586 (GRCm38) |
missense |
probably benign |
0.10 |
|
BB012:Nlrp4a
|
UTSW |
7 |
26,450,586 (GRCm38) |
missense |
probably benign |
0.10 |
|
D3080:Nlrp4a
|
UTSW |
7 |
26,444,341 (GRCm38) |
missense |
probably benign |
0.22 |
|
P0019:Nlrp4a
|
UTSW |
7 |
26,449,637 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0020:Nlrp4a
|
UTSW |
7 |
26,450,372 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0240:Nlrp4a
|
UTSW |
7 |
26,462,516 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0240:Nlrp4a
|
UTSW |
7 |
26,462,516 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0372:Nlrp4a
|
UTSW |
7 |
26,449,232 (GRCm38) |
splice site |
probably benign |
|
|
R0466:Nlrp4a
|
UTSW |
7 |
26,462,620 (GRCm38) |
splice site |
probably benign |
|
|
R0544:Nlrp4a
|
UTSW |
7 |
26,457,130 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1006:Nlrp4a
|
UTSW |
7 |
26,453,467 (GRCm38) |
missense |
probably benign |
0.30 |
|
R1072:Nlrp4a
|
UTSW |
7 |
26,444,435 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1432:Nlrp4a
|
UTSW |
7 |
26,464,197 (GRCm38) |
frame shift |
probably null |
|
|
R1655:Nlrp4a
|
UTSW |
7 |
26,449,651 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R1696:Nlrp4a
|
UTSW |
7 |
26,450,534 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2041:Nlrp4a
|
UTSW |
7 |
26,450,186 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R2091:Nlrp4a
|
UTSW |
7 |
26,450,153 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2163:Nlrp4a
|
UTSW |
7 |
26,453,397 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2174:Nlrp4a
|
UTSW |
7 |
26,449,424 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2319:Nlrp4a
|
UTSW |
7 |
26,449,894 (GRCm38) |
missense |
probably benign |
0.10 |
|
R2358:Nlrp4a
|
UTSW |
7 |
26,464,198 (GRCm38) |
missense |
probably benign |
0.03 |
|
R2680:Nlrp4a
|
UTSW |
7 |
26,449,230 (GRCm38) |
splice site |
probably null |
|
|
R3812:Nlrp4a
|
UTSW |
7 |
26,449,693 (GRCm38) |
missense |
probably benign |
|
|
R4114:Nlrp4a
|
UTSW |
7 |
26,449,940 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4664:Nlrp4a
|
UTSW |
7 |
26,449,518 (GRCm38) |
nonsense |
probably null |
|
|
R4676:Nlrp4a
|
UTSW |
7 |
26,450,229 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4708:Nlrp4a
|
UTSW |
7 |
26,464,108 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4728:Nlrp4a
|
UTSW |
7 |
26,475,090 (GRCm38) |
missense |
probably benign |
0.24 |
|
R4815:Nlrp4a
|
UTSW |
7 |
26,450,808 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5007:Nlrp4a
|
UTSW |
7 |
26,462,480 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5253:Nlrp4a
|
UTSW |
7 |
26,450,492 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5262:Nlrp4a
|
UTSW |
7 |
26,459,811 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5441:Nlrp4a
|
UTSW |
7 |
26,454,153 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5639:Nlrp4a
|
UTSW |
7 |
26,457,030 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5641:Nlrp4a
|
UTSW |
7 |
26,450,164 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5771:Nlrp4a
|
UTSW |
7 |
26,453,389 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6312:Nlrp4a
|
UTSW |
7 |
26,449,396 (GRCm38) |
missense |
probably benign |
0.11 |
|
R7131:Nlrp4a
|
UTSW |
7 |
26,449,833 (GRCm38) |
missense |
probably benign |
0.21 |
|
R7149:Nlrp4a
|
UTSW |
7 |
26,450,438 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7348:Nlrp4a
|
UTSW |
7 |
26,444,273 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7384:Nlrp4a
|
UTSW |
7 |
26,449,538 (GRCm38) |
missense |
not run |
|
|
R7548:Nlrp4a
|
UTSW |
7 |
26,450,179 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7566:Nlrp4a
|
UTSW |
7 |
26,449,245 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7646:Nlrp4a
|
UTSW |
7 |
26,449,562 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7692:Nlrp4a
|
UTSW |
7 |
26,449,265 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7902:Nlrp4a
|
UTSW |
7 |
26,450,057 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R7925:Nlrp4a
|
UTSW |
7 |
26,450,586 (GRCm38) |
missense |
probably benign |
0.10 |
|
R7937:Nlrp4a
|
UTSW |
7 |
26,464,146 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7992:Nlrp4a
|
UTSW |
7 |
26,450,645 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8205:Nlrp4a
|
UTSW |
7 |
26,450,794 (GRCm38) |
missense |
probably benign |
|
|
R8477:Nlrp4a
|
UTSW |
7 |
26,459,794 (GRCm38) |
missense |
probably benign |
|
|
R8704:Nlrp4a
|
UTSW |
7 |
26,457,138 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8791:Nlrp4a
|
UTSW |
7 |
26,444,136 (GRCm38) |
splice site |
probably benign |
|
|
R9220:Nlrp4a
|
UTSW |
7 |
26,450,098 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9332:Nlrp4a
|
UTSW |
7 |
26,459,652 (GRCm38) |
missense |
probably damaging |
0.99 |
|
T0975:Nlrp4a
|
UTSW |
7 |
26,449,637 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0022:Nlrp4a
|
UTSW |
7 |
26,444,342 (GRCm38) |
missense |
probably damaging |
0.99 |
|
Z1088:Nlrp4a
|
UTSW |
7 |
26,454,163 (GRCm38) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGACATCCCCATACTACTGGAC -3'
(R):5'- GGTGTCATCGTCCATCTCAAAC -3'
Sequencing Primer
(F):5'- TCCCCATACTACTGGACATTGGAATG -3'
(R):5'- AAACAGCTTCATGCCATCTATCTG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation