Incidental Mutation 'R4835:Ncoa6'
| ID |
373130 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ncoa6
|
| Ensembl Gene |
ENSMUSG00000038369 |
| Gene Name |
nuclear receptor coactivator 6 |
| Synonyms |
ASC-2, RAP250, NRC, AIB3, ASC2, PRIP |
| MMRRC Submission |
042450-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4835 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
155232585-155315741 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 155249053 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1417
(V1417A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118113
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043126]
[ENSMUST00000109670]
[ENSMUST00000123293]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000043126
AA Change: V1417A
PolyPhen 2
Score 0.459 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000045386
Gene: ENSMUSG00000038369
AA Change: V1417A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
47 |
190 |
3.3e-55 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
450 |
597 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
636 |
793 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
low complexity region
|
1543 |
1564 |
N/A |
INTRINSIC |
|
low complexity region
|
1578 |
1599 |
N/A |
INTRINSIC |
|
low complexity region
|
1607 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1808 |
1825 |
N/A |
INTRINSIC |
|
low complexity region
|
1894 |
1908 |
N/A |
INTRINSIC |
|
low complexity region
|
2043 |
2053 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000109670
AA Change: V1417A
PolyPhen 2
Score 0.459 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000105295
Gene: ENSMUSG00000038369
AA Change: V1417A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
45 |
195 |
3.6e-60 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
450 |
597 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
636 |
793 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
low complexity region
|
1543 |
1564 |
N/A |
INTRINSIC |
|
low complexity region
|
1578 |
1599 |
N/A |
INTRINSIC |
|
low complexity region
|
1607 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1808 |
1825 |
N/A |
INTRINSIC |
|
low complexity region
|
1894 |
1908 |
N/A |
INTRINSIC |
|
low complexity region
|
2043 |
2053 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000123293
AA Change: V1417A
PolyPhen 2
Score 0.459 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000118113
Gene: ENSMUSG00000038369
AA Change: V1417A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
45 |
195 |
2.4e-60 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
564 |
573 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146942
|
| Meta Mutation Damage Score |
0.0596 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.8%
|
| Validation Efficiency |
98% (96/98) |
| MGI Phenotype |
PHENOTYPE: Homozygotes for targeted null mutations exhibit retarded embryonic growth and defects of the placenta, heart, liver, and nervous system. Mutants die around midgestation. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930432E11Rik |
A |
T |
7: 29,274,326 (GRCm39) |
|
noncoding transcript |
Het |
| 4933434E20Rik |
A |
G |
3: 89,970,516 (GRCm39) |
N17D |
probably benign |
Het |
| A1bg |
T |
C |
15: 60,792,100 (GRCm39) |
D176G |
probably benign |
Het |
| Abcg5 |
A |
T |
17: 84,966,076 (GRCm39) |
M428K |
possibly damaging |
Het |
| Adam1a |
A |
T |
5: 121,657,752 (GRCm39) |
C514S |
probably damaging |
Het |
| Angptl3 |
A |
G |
4: 98,925,649 (GRCm39) |
Q325R |
probably benign |
Het |
| Ankrd26 |
C |
T |
6: 118,525,811 (GRCm39) |
W378* |
probably null |
Het |
| Apob |
T |
C |
12: 8,065,391 (GRCm39) |
V4087A |
possibly damaging |
Het |
| Auts2 |
A |
G |
5: 131,494,931 (GRCm39) |
I117T |
probably damaging |
Het |
| AW146154 |
T |
A |
7: 41,129,892 (GRCm39) |
E408V |
probably damaging |
Het |
| Bicd1 |
A |
T |
6: 149,385,588 (GRCm39) |
N107I |
probably benign |
Het |
| Blm |
T |
C |
7: 80,159,294 (GRCm39) |
S281G |
probably benign |
Het |
| Btaf1 |
T |
A |
19: 36,979,858 (GRCm39) |
D1542E |
probably benign |
Het |
| C2cd2l |
A |
G |
9: 44,226,442 (GRCm39) |
|
probably null |
Het |
| Capn8 |
C |
A |
1: 182,432,116 (GRCm39) |
N362K |
probably damaging |
Het |
| Ccdc14 |
T |
G |
16: 34,525,408 (GRCm39) |
S186A |
probably damaging |
Het |
| Cdca4 |
A |
G |
12: 112,785,167 (GRCm39) |
L187P |
probably damaging |
Het |
| Chil6 |
T |
A |
3: 106,313,290 (GRCm39) |
K20* |
probably null |
Het |
| Cmss1 |
A |
T |
16: 57,136,545 (GRCm39) |
L109* |
probably null |
Het |
| Cmtm6 |
G |
T |
9: 114,560,410 (GRCm39) |
W36L |
probably benign |
Het |
| Cnksr3 |
T |
G |
10: 7,110,757 (GRCm39) |
I35L |
possibly damaging |
Het |
| Col4a2 |
G |
T |
8: 11,473,570 (GRCm39) |
G534* |
probably null |
Het |
| Col5a1 |
T |
G |
2: 27,915,656 (GRCm39) |
V180G |
probably damaging |
Het |
| Ctnna3 |
T |
C |
10: 63,417,723 (GRCm39) |
F154L |
probably benign |
Het |
| Fabp7 |
G |
A |
10: 57,661,676 (GRCm39) |
V50M |
possibly damaging |
Het |
| Fam170a |
T |
A |
18: 50,415,050 (GRCm39) |
V232D |
probably damaging |
Het |
| Fam186a |
T |
G |
15: 99,843,689 (GRCm39) |
T852P |
unknown |
Het |
| Fam20a |
T |
C |
11: 109,564,389 (GRCm39) |
I455V |
probably benign |
Het |
| Fbxl6 |
C |
T |
15: 76,421,004 (GRCm39) |
V324M |
probably damaging |
Het |
| Galnt18 |
T |
C |
7: 111,378,730 (GRCm39) |
T9A |
probably damaging |
Het |
| Golgb1 |
T |
A |
16: 36,711,769 (GRCm39) |
M191K |
possibly damaging |
Het |
| Gpld1 |
A |
G |
13: 25,166,699 (GRCm39) |
T650A |
probably benign |
Het |
| Gprc5d |
A |
G |
6: 135,093,515 (GRCm39) |
F131L |
probably benign |
Het |
| H2az2 |
C |
T |
11: 6,389,437 (GRCm39) |
G7E |
unknown |
Het |
| Haus4 |
A |
T |
14: 54,783,292 (GRCm39) |
|
probably null |
Het |
| Helq |
A |
G |
5: 100,922,029 (GRCm39) |
I725T |
possibly damaging |
Het |
| Igsf23 |
T |
A |
7: 19,675,755 (GRCm39) |
D117V |
possibly damaging |
Het |
| Kiz |
A |
T |
2: 146,784,008 (GRCm39) |
S514C |
probably damaging |
Het |
| Klhl6 |
A |
T |
16: 19,775,783 (GRCm39) |
N258K |
probably benign |
Het |
| Krt72 |
G |
C |
15: 101,689,508 (GRCm39) |
|
probably null |
Het |
| Large1 |
A |
T |
8: 73,774,975 (GRCm39) |
I245N |
probably damaging |
Het |
| Lrrc31 |
T |
C |
3: 30,733,306 (GRCm39) |
I469M |
probably damaging |
Het |
| Lypd4 |
T |
A |
7: 24,566,121 (GRCm39) |
I68F |
probably benign |
Het |
| Mast1 |
A |
G |
8: 85,650,408 (GRCm39) |
S442P |
probably damaging |
Het |
| Mmp20 |
T |
A |
9: 7,645,300 (GRCm39) |
H283Q |
probably benign |
Het |
| Mrps5 |
G |
A |
2: 127,445,627 (GRCm39) |
V385M |
possibly damaging |
Het |
| Ms4a15 |
T |
C |
19: 10,956,590 (GRCm39) |
K241E |
possibly damaging |
Het |
| Myt1 |
A |
G |
2: 181,439,255 (GRCm39) |
E259G |
probably damaging |
Het |
| Myt1l |
C |
A |
12: 29,945,304 (GRCm39) |
T1023K |
unknown |
Het |
| Ncapd3 |
T |
C |
9: 26,997,342 (GRCm39) |
L1221P |
probably damaging |
Het |
| Nmnat1 |
A |
G |
4: 149,557,802 (GRCm39) |
V80A |
possibly damaging |
Het |
| Nwd2 |
A |
G |
5: 63,965,189 (GRCm39) |
E1591G |
probably benign |
Het |
| Or10ac1 |
A |
G |
6: 42,515,770 (GRCm39) |
F62S |
probably damaging |
Het |
| Or8j3b |
A |
G |
2: 86,204,853 (GRCm39) |
L301S |
possibly damaging |
Het |
| Osbpl1a |
A |
T |
18: 12,901,593 (GRCm39) |
|
probably null |
Het |
| Papln |
T |
C |
12: 83,821,194 (GRCm39) |
I204T |
probably damaging |
Het |
| Phf1 |
A |
G |
17: 27,153,652 (GRCm39) |
T97A |
probably benign |
Het |
| Plxnb1 |
A |
G |
9: 108,934,442 (GRCm39) |
D890G |
probably damaging |
Het |
| Ppp1r12b |
G |
T |
1: 134,883,471 (GRCm39) |
A17E |
probably benign |
Het |
| Ptgir |
A |
G |
7: 16,640,794 (GRCm39) |
M29V |
possibly damaging |
Het |
| Rbp2 |
G |
A |
9: 98,389,876 (GRCm39) |
C96Y |
probably damaging |
Het |
| Rgmb |
A |
T |
17: 16,027,624 (GRCm39) |
M365K |
possibly damaging |
Het |
| Ric1 |
A |
G |
19: 29,572,936 (GRCm39) |
N792S |
possibly damaging |
Het |
| Ruvbl1 |
T |
C |
6: 88,474,211 (GRCm39) |
Y405H |
possibly damaging |
Het |
| Scaf4 |
A |
G |
16: 90,047,195 (GRCm39) |
M394T |
unknown |
Het |
| Siglech |
T |
A |
7: 55,418,177 (GRCm39) |
C48* |
probably null |
Het |
| Skic2 |
A |
G |
17: 35,061,897 (GRCm39) |
V695A |
possibly damaging |
Het |
| Slc2a5 |
A |
G |
4: 150,224,462 (GRCm39) |
T320A |
probably benign |
Het |
| Slc6a7 |
T |
C |
18: 61,135,277 (GRCm39) |
Y417C |
probably benign |
Het |
| Sox21 |
A |
G |
14: 118,472,336 (GRCm39) |
C238R |
possibly damaging |
Het |
| Tbata |
A |
T |
10: 61,019,132 (GRCm39) |
K109N |
probably damaging |
Het |
| Tecpr2 |
T |
G |
12: 110,921,164 (GRCm39) |
S1246A |
probably benign |
Het |
| Tekt3 |
A |
G |
11: 62,972,085 (GRCm39) |
D247G |
probably benign |
Het |
| Tenm3 |
A |
T |
8: 48,766,271 (GRCm39) |
|
probably null |
Het |
| Thada |
A |
T |
17: 84,748,532 (GRCm39) |
|
probably null |
Het |
| Tpcn2 |
C |
T |
7: 144,826,088 (GRCm39) |
G204R |
probably damaging |
Het |
| Tpm2 |
T |
C |
4: 43,519,220 (GRCm39) |
|
probably null |
Het |
| Trbv24 |
T |
C |
6: 41,195,026 (GRCm39) |
|
probably benign |
Het |
| Tyw1 |
A |
G |
5: 130,305,899 (GRCm39) |
R341G |
probably benign |
Het |
| Vmn1r183 |
T |
G |
7: 23,754,564 (GRCm39) |
N122K |
probably benign |
Het |
| Vmn2r61 |
T |
A |
7: 41,916,459 (GRCm39) |
H357Q |
possibly damaging |
Het |
| Vps13b |
C |
T |
15: 35,869,518 (GRCm39) |
T2674I |
probably damaging |
Het |
| Vps13b |
T |
C |
15: 35,910,439 (GRCm39) |
L3401P |
probably benign |
Het |
| Vps16 |
T |
G |
2: 130,280,220 (GRCm39) |
|
probably benign |
Het |
| Vrtn |
T |
A |
12: 84,696,468 (GRCm39) |
I406N |
probably damaging |
Het |
| Vwa8 |
A |
T |
14: 79,172,053 (GRCm39) |
Y278F |
probably benign |
Het |
| Washc4 |
A |
T |
10: 83,415,376 (GRCm39) |
I789F |
possibly damaging |
Het |
| Zbtb20 |
C |
A |
16: 43,438,761 (GRCm39) |
T627K |
probably damaging |
Het |
| Zfyve16 |
A |
T |
13: 92,658,693 (GRCm39) |
I406K |
probably benign |
Het |
| Zfyve9 |
A |
C |
4: 108,575,195 (GRCm39) |
S629A |
possibly damaging |
Het |
| Zpld1 |
A |
T |
16: 55,068,618 (GRCm39) |
N164K |
probably damaging |
Het |
|
| Other mutations in Ncoa6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:Ncoa6
|
APN |
2 |
155,248,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00849:Ncoa6
|
APN |
2 |
155,263,608 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL00933:Ncoa6
|
APN |
2 |
155,257,317 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00981:Ncoa6
|
APN |
2 |
155,248,099 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01420:Ncoa6
|
APN |
2 |
155,249,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02160:Ncoa6
|
APN |
2 |
155,263,003 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL03049:Ncoa6
|
APN |
2 |
155,260,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03194:Ncoa6
|
APN |
2 |
155,257,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03269:Ncoa6
|
APN |
2 |
155,248,409 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03299:Ncoa6
|
APN |
2 |
155,249,207 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03306:Ncoa6
|
APN |
2 |
155,247,427 (GRCm39) |
missense |
probably benign |
0.30 |
|
alcoa
|
UTSW |
2 |
155,244,584 (GRCm39) |
unclassified |
probably benign |
|
|
Aluminum
|
UTSW |
2 |
155,241,613 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
balboa
|
UTSW |
2 |
155,248,869 (GRCm39) |
missense |
probably benign |
0.05 |
|
mauna_loa
|
UTSW |
2 |
155,257,147 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4466001:Ncoa6
|
UTSW |
2 |
155,247,577 (GRCm39) |
missense |
probably benign |
|
|
R0011:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0014:Ncoa6
|
UTSW |
2 |
155,279,963 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0079:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0080:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0081:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0164:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0166:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0172:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0173:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0245:Ncoa6
|
UTSW |
2 |
155,233,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0284:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0285:Ncoa6
|
UTSW |
2 |
155,257,621 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0285:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0288:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0539:Ncoa6
|
UTSW |
2 |
155,257,617 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0652:Ncoa6
|
UTSW |
2 |
155,233,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0781:Ncoa6
|
UTSW |
2 |
155,253,440 (GRCm39) |
splice site |
probably benign |
|
|
R1053:Ncoa6
|
UTSW |
2 |
155,275,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1110:Ncoa6
|
UTSW |
2 |
155,253,440 (GRCm39) |
splice site |
probably benign |
|
|
R1420:Ncoa6
|
UTSW |
2 |
155,263,073 (GRCm39) |
nonsense |
probably null |
|
|
R1521:Ncoa6
|
UTSW |
2 |
155,257,142 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1541:Ncoa6
|
UTSW |
2 |
155,257,224 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1677:Ncoa6
|
UTSW |
2 |
155,244,584 (GRCm39) |
unclassified |
probably benign |
|
|
R1858:Ncoa6
|
UTSW |
2 |
155,263,559 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1954:Ncoa6
|
UTSW |
2 |
155,248,741 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1955:Ncoa6
|
UTSW |
2 |
155,248,741 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2040:Ncoa6
|
UTSW |
2 |
155,248,000 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2087:Ncoa6
|
UTSW |
2 |
155,248,079 (GRCm39) |
nonsense |
probably null |
|
|
R2159:Ncoa6
|
UTSW |
2 |
155,249,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2278:Ncoa6
|
UTSW |
2 |
155,249,570 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2696:Ncoa6
|
UTSW |
2 |
155,279,935 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2891:Ncoa6
|
UTSW |
2 |
155,279,881 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3618:Ncoa6
|
UTSW |
2 |
155,249,709 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3747:Ncoa6
|
UTSW |
2 |
155,253,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3778:Ncoa6
|
UTSW |
2 |
155,263,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3784:Ncoa6
|
UTSW |
2 |
155,249,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3802:Ncoa6
|
UTSW |
2 |
155,247,484 (GRCm39) |
missense |
probably benign |
|
|
R3820:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3821:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3822:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3870:Ncoa6
|
UTSW |
2 |
155,257,477 (GRCm39) |
splice site |
probably null |
|
|
R4037:Ncoa6
|
UTSW |
2 |
155,249,290 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4488:Ncoa6
|
UTSW |
2 |
155,249,396 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4719:Ncoa6
|
UTSW |
2 |
155,233,081 (GRCm39) |
unclassified |
probably benign |
|
|
R4732:Ncoa6
|
UTSW |
2 |
155,263,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Ncoa6
|
UTSW |
2 |
155,263,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4829:Ncoa6
|
UTSW |
2 |
155,257,147 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Ncoa6
|
UTSW |
2 |
155,248,687 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4967:Ncoa6
|
UTSW |
2 |
155,263,252 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5021:Ncoa6
|
UTSW |
2 |
155,248,869 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5234:Ncoa6
|
UTSW |
2 |
155,279,933 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5356:Ncoa6
|
UTSW |
2 |
155,263,112 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5358:Ncoa6
|
UTSW |
2 |
155,248,907 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5375:Ncoa6
|
UTSW |
2 |
155,275,915 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5412:Ncoa6
|
UTSW |
2 |
155,249,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5579:Ncoa6
|
UTSW |
2 |
155,248,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5618:Ncoa6
|
UTSW |
2 |
155,279,817 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5641:Ncoa6
|
UTSW |
2 |
155,263,756 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5757:Ncoa6
|
UTSW |
2 |
155,253,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Ncoa6
|
UTSW |
2 |
155,250,061 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5778:Ncoa6
|
UTSW |
2 |
155,248,688 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5852:Ncoa6
|
UTSW |
2 |
155,247,419 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5940:Ncoa6
|
UTSW |
2 |
155,257,785 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6155:Ncoa6
|
UTSW |
2 |
155,249,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6374:Ncoa6
|
UTSW |
2 |
155,263,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6389:Ncoa6
|
UTSW |
2 |
155,237,736 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6669:Ncoa6
|
UTSW |
2 |
155,241,613 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7097:Ncoa6
|
UTSW |
2 |
155,279,983 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7385:Ncoa6
|
UTSW |
2 |
155,249,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7963:Ncoa6
|
UTSW |
2 |
155,247,916 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8356:Ncoa6
|
UTSW |
2 |
155,248,172 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8698:Ncoa6
|
UTSW |
2 |
155,257,041 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8859:Ncoa6
|
UTSW |
2 |
155,248,388 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R8870:Ncoa6
|
UTSW |
2 |
155,263,078 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9041:Ncoa6
|
UTSW |
2 |
155,257,450 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9062:Ncoa6
|
UTSW |
2 |
155,263,348 (GRCm39) |
missense |
probably benign |
0.42 |
|
R9088:Ncoa6
|
UTSW |
2 |
155,249,726 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9225:Ncoa6
|
UTSW |
2 |
155,249,441 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9445:Ncoa6
|
UTSW |
2 |
155,250,063 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9497:Ncoa6
|
UTSW |
2 |
155,248,238 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9514:Ncoa6
|
UTSW |
2 |
155,248,133 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9656:Ncoa6
|
UTSW |
2 |
155,274,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9720:Ncoa6
|
UTSW |
2 |
155,250,304 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9732:Ncoa6
|
UTSW |
2 |
155,244,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF033:Ncoa6
|
UTSW |
2 |
155,263,651 (GRCm39) |
small deletion |
probably benign |
|
|
RF040:Ncoa6
|
UTSW |
2 |
155,263,651 (GRCm39) |
small deletion |
probably benign |
|
|
RF048:Ncoa6
|
UTSW |
2 |
155,263,632 (GRCm39) |
small deletion |
probably benign |
|
|
X0017:Ncoa6
|
UTSW |
2 |
155,248,460 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1176:Ncoa6
|
UTSW |
2 |
155,263,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Ncoa6
|
UTSW |
2 |
155,263,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ncoa6
|
UTSW |
2 |
155,248,062 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTCTTCAACACTGGGGAGTTTG -3'
(R):5'- AAGTCCTGGAAGGCAAAACTC -3'
Sequencing Primer
(F):5'- GTTAGGATCCAATGGTTGCCC -3'
(R):5'- AAGCTCCTAAACTTACTCTGGC -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation