Incidental Mutation 'R4835:Plxnb1'
| ID |
373165 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb1
|
| Ensembl Gene |
ENSMUSG00000053646 |
| Gene Name |
plexin B1 |
| Synonyms |
2900002G15Rik |
| MMRRC Submission |
042450-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4835 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
108924457-108948985 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 108934442 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 890
(D890G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071966
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072093]
[ENSMUST00000130366]
[ENSMUST00000131462]
|
| AlphaFold |
Q8CJH3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000072093
AA Change: D890G
PolyPhen 2
Score 0.959 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000071966
Gene: ENSMUSG00000053646
AA Change: D890G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
35 |
463 |
5.84e-101 |
SMART |
|
PSI
|
481 |
534 |
1.17e-13 |
SMART |
|
PSI
|
628 |
678 |
6.97e-3 |
SMART |
|
low complexity region
|
691 |
706 |
N/A |
INTRINSIC |
|
low complexity region
|
752 |
771 |
N/A |
INTRINSIC |
|
PSI
|
1019 |
1066 |
2.06e-5 |
SMART |
|
IPT
|
1067 |
1158 |
7.48e-18 |
SMART |
|
IPT
|
1159 |
1247 |
3.97e-22 |
SMART |
|
IPT
|
1249 |
1359 |
6.09e-9 |
SMART |
|
low complexity region
|
1483 |
1494 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1546 |
2086 |
6.5e-230 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000130366
|
| SMART Domains |
Protein: ENSMUSP00000114358
Gene: ENSMUSG00000053646
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:Sema
|
35 |
138 |
7.5e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131462
|
| SMART Domains |
Protein: ENSMUSP00000115265
Gene: ENSMUSG00000053646
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:Sema
|
35 |
138 |
7.5e-11 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192117
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192988
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194734
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195364
|
| Meta Mutation Damage Score |
0.1432 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.8%
|
| Validation Efficiency |
98% (96/98) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930432E11Rik |
A |
T |
7: 29,274,326 (GRCm39) |
|
noncoding transcript |
Het |
| 4933434E20Rik |
A |
G |
3: 89,970,516 (GRCm39) |
N17D |
probably benign |
Het |
| A1bg |
T |
C |
15: 60,792,100 (GRCm39) |
D176G |
probably benign |
Het |
| Abcg5 |
A |
T |
17: 84,966,076 (GRCm39) |
M428K |
possibly damaging |
Het |
| Adam1a |
A |
T |
5: 121,657,752 (GRCm39) |
C514S |
probably damaging |
Het |
| Angptl3 |
A |
G |
4: 98,925,649 (GRCm39) |
Q325R |
probably benign |
Het |
| Ankrd26 |
C |
T |
6: 118,525,811 (GRCm39) |
W378* |
probably null |
Het |
| Apob |
T |
C |
12: 8,065,391 (GRCm39) |
V4087A |
possibly damaging |
Het |
| Auts2 |
A |
G |
5: 131,494,931 (GRCm39) |
I117T |
probably damaging |
Het |
| AW146154 |
T |
A |
7: 41,129,892 (GRCm39) |
E408V |
probably damaging |
Het |
| Bicd1 |
A |
T |
6: 149,385,588 (GRCm39) |
N107I |
probably benign |
Het |
| Blm |
T |
C |
7: 80,159,294 (GRCm39) |
S281G |
probably benign |
Het |
| Btaf1 |
T |
A |
19: 36,979,858 (GRCm39) |
D1542E |
probably benign |
Het |
| C2cd2l |
A |
G |
9: 44,226,442 (GRCm39) |
|
probably null |
Het |
| Capn8 |
C |
A |
1: 182,432,116 (GRCm39) |
N362K |
probably damaging |
Het |
| Ccdc14 |
T |
G |
16: 34,525,408 (GRCm39) |
S186A |
probably damaging |
Het |
| Cdca4 |
A |
G |
12: 112,785,167 (GRCm39) |
L187P |
probably damaging |
Het |
| Chil6 |
T |
A |
3: 106,313,290 (GRCm39) |
K20* |
probably null |
Het |
| Cmss1 |
A |
T |
16: 57,136,545 (GRCm39) |
L109* |
probably null |
Het |
| Cmtm6 |
G |
T |
9: 114,560,410 (GRCm39) |
W36L |
probably benign |
Het |
| Cnksr3 |
T |
G |
10: 7,110,757 (GRCm39) |
I35L |
possibly damaging |
Het |
| Col4a2 |
G |
T |
8: 11,473,570 (GRCm39) |
G534* |
probably null |
Het |
| Col5a1 |
T |
G |
2: 27,915,656 (GRCm39) |
V180G |
probably damaging |
Het |
| Ctnna3 |
T |
C |
10: 63,417,723 (GRCm39) |
F154L |
probably benign |
Het |
| Fabp7 |
G |
A |
10: 57,661,676 (GRCm39) |
V50M |
possibly damaging |
Het |
| Fam170a |
T |
A |
18: 50,415,050 (GRCm39) |
V232D |
probably damaging |
Het |
| Fam186a |
T |
G |
15: 99,843,689 (GRCm39) |
T852P |
unknown |
Het |
| Fam20a |
T |
C |
11: 109,564,389 (GRCm39) |
I455V |
probably benign |
Het |
| Fbxl6 |
C |
T |
15: 76,421,004 (GRCm39) |
V324M |
probably damaging |
Het |
| Galnt18 |
T |
C |
7: 111,378,730 (GRCm39) |
T9A |
probably damaging |
Het |
| Golgb1 |
T |
A |
16: 36,711,769 (GRCm39) |
M191K |
possibly damaging |
Het |
| Gpld1 |
A |
G |
13: 25,166,699 (GRCm39) |
T650A |
probably benign |
Het |
| Gprc5d |
A |
G |
6: 135,093,515 (GRCm39) |
F131L |
probably benign |
Het |
| H2az2 |
C |
T |
11: 6,389,437 (GRCm39) |
G7E |
unknown |
Het |
| Haus4 |
A |
T |
14: 54,783,292 (GRCm39) |
|
probably null |
Het |
| Helq |
A |
G |
5: 100,922,029 (GRCm39) |
I725T |
possibly damaging |
Het |
| Igsf23 |
T |
A |
7: 19,675,755 (GRCm39) |
D117V |
possibly damaging |
Het |
| Kiz |
A |
T |
2: 146,784,008 (GRCm39) |
S514C |
probably damaging |
Het |
| Klhl6 |
A |
T |
16: 19,775,783 (GRCm39) |
N258K |
probably benign |
Het |
| Krt72 |
G |
C |
15: 101,689,508 (GRCm39) |
|
probably null |
Het |
| Large1 |
A |
T |
8: 73,774,975 (GRCm39) |
I245N |
probably damaging |
Het |
| Lrrc31 |
T |
C |
3: 30,733,306 (GRCm39) |
I469M |
probably damaging |
Het |
| Lypd4 |
T |
A |
7: 24,566,121 (GRCm39) |
I68F |
probably benign |
Het |
| Mast1 |
A |
G |
8: 85,650,408 (GRCm39) |
S442P |
probably damaging |
Het |
| Mmp20 |
T |
A |
9: 7,645,300 (GRCm39) |
H283Q |
probably benign |
Het |
| Mrps5 |
G |
A |
2: 127,445,627 (GRCm39) |
V385M |
possibly damaging |
Het |
| Ms4a15 |
T |
C |
19: 10,956,590 (GRCm39) |
K241E |
possibly damaging |
Het |
| Myt1 |
A |
G |
2: 181,439,255 (GRCm39) |
E259G |
probably damaging |
Het |
| Myt1l |
C |
A |
12: 29,945,304 (GRCm39) |
T1023K |
unknown |
Het |
| Ncapd3 |
T |
C |
9: 26,997,342 (GRCm39) |
L1221P |
probably damaging |
Het |
| Ncoa6 |
A |
G |
2: 155,249,053 (GRCm39) |
V1417A |
possibly damaging |
Het |
| Nmnat1 |
A |
G |
4: 149,557,802 (GRCm39) |
V80A |
possibly damaging |
Het |
| Nwd2 |
A |
G |
5: 63,965,189 (GRCm39) |
E1591G |
probably benign |
Het |
| Or10ac1 |
A |
G |
6: 42,515,770 (GRCm39) |
F62S |
probably damaging |
Het |
| Or8j3b |
A |
G |
2: 86,204,853 (GRCm39) |
L301S |
possibly damaging |
Het |
| Osbpl1a |
A |
T |
18: 12,901,593 (GRCm39) |
|
probably null |
Het |
| Papln |
T |
C |
12: 83,821,194 (GRCm39) |
I204T |
probably damaging |
Het |
| Phf1 |
A |
G |
17: 27,153,652 (GRCm39) |
T97A |
probably benign |
Het |
| Ppp1r12b |
G |
T |
1: 134,883,471 (GRCm39) |
A17E |
probably benign |
Het |
| Ptgir |
A |
G |
7: 16,640,794 (GRCm39) |
M29V |
possibly damaging |
Het |
| Rbp2 |
G |
A |
9: 98,389,876 (GRCm39) |
C96Y |
probably damaging |
Het |
| Rgmb |
A |
T |
17: 16,027,624 (GRCm39) |
M365K |
possibly damaging |
Het |
| Ric1 |
A |
G |
19: 29,572,936 (GRCm39) |
N792S |
possibly damaging |
Het |
| Ruvbl1 |
T |
C |
6: 88,474,211 (GRCm39) |
Y405H |
possibly damaging |
Het |
| Scaf4 |
A |
G |
16: 90,047,195 (GRCm39) |
M394T |
unknown |
Het |
| Siglech |
T |
A |
7: 55,418,177 (GRCm39) |
C48* |
probably null |
Het |
| Skic2 |
A |
G |
17: 35,061,897 (GRCm39) |
V695A |
possibly damaging |
Het |
| Slc2a5 |
A |
G |
4: 150,224,462 (GRCm39) |
T320A |
probably benign |
Het |
| Slc6a7 |
T |
C |
18: 61,135,277 (GRCm39) |
Y417C |
probably benign |
Het |
| Sox21 |
A |
G |
14: 118,472,336 (GRCm39) |
C238R |
possibly damaging |
Het |
| Tbata |
A |
T |
10: 61,019,132 (GRCm39) |
K109N |
probably damaging |
Het |
| Tecpr2 |
T |
G |
12: 110,921,164 (GRCm39) |
S1246A |
probably benign |
Het |
| Tekt3 |
A |
G |
11: 62,972,085 (GRCm39) |
D247G |
probably benign |
Het |
| Tenm3 |
A |
T |
8: 48,766,271 (GRCm39) |
|
probably null |
Het |
| Thada |
A |
T |
17: 84,748,532 (GRCm39) |
|
probably null |
Het |
| Tpcn2 |
C |
T |
7: 144,826,088 (GRCm39) |
G204R |
probably damaging |
Het |
| Tpm2 |
T |
C |
4: 43,519,220 (GRCm39) |
|
probably null |
Het |
| Trbv24 |
T |
C |
6: 41,195,026 (GRCm39) |
|
probably benign |
Het |
| Tyw1 |
A |
G |
5: 130,305,899 (GRCm39) |
R341G |
probably benign |
Het |
| Vmn1r183 |
T |
G |
7: 23,754,564 (GRCm39) |
N122K |
probably benign |
Het |
| Vmn2r61 |
T |
A |
7: 41,916,459 (GRCm39) |
H357Q |
possibly damaging |
Het |
| Vps13b |
C |
T |
15: 35,869,518 (GRCm39) |
T2674I |
probably damaging |
Het |
| Vps13b |
T |
C |
15: 35,910,439 (GRCm39) |
L3401P |
probably benign |
Het |
| Vps16 |
T |
G |
2: 130,280,220 (GRCm39) |
|
probably benign |
Het |
| Vrtn |
T |
A |
12: 84,696,468 (GRCm39) |
I406N |
probably damaging |
Het |
| Vwa8 |
A |
T |
14: 79,172,053 (GRCm39) |
Y278F |
probably benign |
Het |
| Washc4 |
A |
T |
10: 83,415,376 (GRCm39) |
I789F |
possibly damaging |
Het |
| Zbtb20 |
C |
A |
16: 43,438,761 (GRCm39) |
T627K |
probably damaging |
Het |
| Zfyve16 |
A |
T |
13: 92,658,693 (GRCm39) |
I406K |
probably benign |
Het |
| Zfyve9 |
A |
C |
4: 108,575,195 (GRCm39) |
S629A |
possibly damaging |
Het |
| Zpld1 |
A |
T |
16: 55,068,618 (GRCm39) |
N164K |
probably damaging |
Het |
|
| Other mutations in Plxnb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00593:Plxnb1
|
APN |
9 |
108,942,936 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01014:Plxnb1
|
APN |
9 |
108,935,102 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01142:Plxnb1
|
APN |
9 |
108,931,765 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01454:Plxnb1
|
APN |
9 |
108,942,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01469:Plxnb1
|
APN |
9 |
108,934,483 (GRCm39) |
intron |
probably benign |
|
|
IGL01530:Plxnb1
|
APN |
9 |
108,939,473 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01599:Plxnb1
|
APN |
9 |
108,939,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01968:Plxnb1
|
APN |
9 |
108,930,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02175:Plxnb1
|
APN |
9 |
108,929,914 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02216:Plxnb1
|
APN |
9 |
108,929,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Plxnb1
|
APN |
9 |
108,941,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02311:Plxnb1
|
APN |
9 |
108,930,190 (GRCm39) |
missense |
probably benign |
|
|
IGL02645:Plxnb1
|
APN |
9 |
108,943,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL03076:Plxnb1
|
APN |
9 |
108,935,970 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03107:Plxnb1
|
APN |
9 |
108,934,054 (GRCm39) |
missense |
probably benign |
|
|
IGL03343:Plxnb1
|
APN |
9 |
108,943,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4431001:Plxnb1
|
UTSW |
9 |
108,929,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0117:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0843:Plxnb1
|
UTSW |
9 |
108,942,769 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0970:Plxnb1
|
UTSW |
9 |
108,932,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Plxnb1
|
UTSW |
9 |
108,931,210 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1342:Plxnb1
|
UTSW |
9 |
108,929,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1386:Plxnb1
|
UTSW |
9 |
108,930,091 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1419:Plxnb1
|
UTSW |
9 |
108,943,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1445:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
probably null |
|
|
R1548:Plxnb1
|
UTSW |
9 |
108,929,968 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1621:Plxnb1
|
UTSW |
9 |
108,935,873 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1658:Plxnb1
|
UTSW |
9 |
108,931,939 (GRCm39) |
nonsense |
probably null |
|
|
R1727:Plxnb1
|
UTSW |
9 |
108,930,125 (GRCm39) |
splice site |
probably null |
|
|
R1750:Plxnb1
|
UTSW |
9 |
108,940,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1795:Plxnb1
|
UTSW |
9 |
108,929,813 (GRCm39) |
missense |
probably benign |
|
|
R1929:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R1935:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1936:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2014:Plxnb1
|
UTSW |
9 |
108,935,687 (GRCm39) |
splice site |
probably benign |
|
|
R2057:Plxnb1
|
UTSW |
9 |
108,938,294 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2102:Plxnb1
|
UTSW |
9 |
108,944,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R2422:Plxnb1
|
UTSW |
9 |
108,937,506 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2881:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3409:Plxnb1
|
UTSW |
9 |
108,935,681 (GRCm39) |
splice site |
probably null |
|
|
R3417:Plxnb1
|
UTSW |
9 |
108,929,828 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3756:Plxnb1
|
UTSW |
9 |
108,942,526 (GRCm39) |
unclassified |
probably benign |
|
|
R3788:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3789:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4042:Plxnb1
|
UTSW |
9 |
108,934,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4289:Plxnb1
|
UTSW |
9 |
108,943,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4396:Plxnb1
|
UTSW |
9 |
108,929,291 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4564:Plxnb1
|
UTSW |
9 |
108,942,488 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4676:Plxnb1
|
UTSW |
9 |
108,939,503 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4706:Plxnb1
|
UTSW |
9 |
108,941,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Plxnb1
|
UTSW |
9 |
108,939,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4796:Plxnb1
|
UTSW |
9 |
108,943,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4901:Plxnb1
|
UTSW |
9 |
108,934,027 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4952:Plxnb1
|
UTSW |
9 |
108,943,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Plxnb1
|
UTSW |
9 |
108,935,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5015:Plxnb1
|
UTSW |
9 |
108,929,498 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5029:Plxnb1
|
UTSW |
9 |
108,943,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Plxnb1
|
UTSW |
9 |
108,940,761 (GRCm39) |
splice site |
probably null |
|
|
R5256:Plxnb1
|
UTSW |
9 |
108,943,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5285:Plxnb1
|
UTSW |
9 |
108,937,527 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5431:Plxnb1
|
UTSW |
9 |
108,929,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5444:Plxnb1
|
UTSW |
9 |
108,935,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5546:Plxnb1
|
UTSW |
9 |
108,929,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5852:Plxnb1
|
UTSW |
9 |
108,935,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5892:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6020:Plxnb1
|
UTSW |
9 |
108,945,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6177:Plxnb1
|
UTSW |
9 |
108,931,993 (GRCm39) |
splice site |
probably null |
|
|
R6193:Plxnb1
|
UTSW |
9 |
108,933,971 (GRCm39) |
missense |
probably benign |
|
|
R6274:Plxnb1
|
UTSW |
9 |
108,941,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6310:Plxnb1
|
UTSW |
9 |
108,938,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6404:Plxnb1
|
UTSW |
9 |
108,945,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6422:Plxnb1
|
UTSW |
9 |
108,937,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6479:Plxnb1
|
UTSW |
9 |
108,940,733 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6555:Plxnb1
|
UTSW |
9 |
108,937,473 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6646:Plxnb1
|
UTSW |
9 |
108,937,895 (GRCm39) |
missense |
probably benign |
|
|
R6648:Plxnb1
|
UTSW |
9 |
108,933,398 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6661:Plxnb1
|
UTSW |
9 |
108,933,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6674:Plxnb1
|
UTSW |
9 |
108,937,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6734:Plxnb1
|
UTSW |
9 |
108,937,988 (GRCm39) |
nonsense |
probably null |
|
|
R6859:Plxnb1
|
UTSW |
9 |
108,935,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6948:Plxnb1
|
UTSW |
9 |
108,945,702 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7030:Plxnb1
|
UTSW |
9 |
108,941,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Plxnb1
|
UTSW |
9 |
108,929,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7204:Plxnb1
|
UTSW |
9 |
108,929,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7428:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7443:Plxnb1
|
UTSW |
9 |
108,943,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7527:Plxnb1
|
UTSW |
9 |
108,929,929 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7645:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7680:Plxnb1
|
UTSW |
9 |
108,929,571 (GRCm39) |
nonsense |
probably null |
|
|
R7866:Plxnb1
|
UTSW |
9 |
108,929,525 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7898:Plxnb1
|
UTSW |
9 |
108,943,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7905:Plxnb1
|
UTSW |
9 |
108,938,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8092:Plxnb1
|
UTSW |
9 |
108,929,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Plxnb1
|
UTSW |
9 |
108,941,146 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8286:Plxnb1
|
UTSW |
9 |
108,935,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Plxnb1
|
UTSW |
9 |
108,938,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8987:Plxnb1
|
UTSW |
9 |
108,937,178 (GRCm39) |
splice site |
probably benign |
|
|
R9176:Plxnb1
|
UTSW |
9 |
108,941,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9698:Plxnb1
|
UTSW |
9 |
108,925,251 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGAAGCCCGTTCTGGATTGG -3'
(R):5'- AGGAGCTCACCCTCTGATTC -3'
Sequencing Primer
(F):5'- TGGCTCACCAAAGGAGGC -3'
(R):5'- CCAAGGGTGAGGCAGTCTGTG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation