Incidental Mutation 'R4835:Osbpl1a'
| ID |
373199 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Osbpl1a
|
| Ensembl Gene |
ENSMUSG00000044252 |
| Gene Name |
oxysterol binding protein-like 1A |
| Synonyms |
G430090F17Rik, LOC328902 |
| MMRRC Submission |
042450-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.095)
|
| Stock # |
R4835 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
12888371-13074898 bp(-) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
A to T
at 12901593 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000122967
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074352]
[ENSMUST00000117361]
[ENSMUST00000118313]
[ENSMUST00000119043]
[ENSMUST00000119512]
[ENSMUST00000121774]
[ENSMUST00000121808]
[ENSMUST00000143077]
[ENSMUST00000121888]
[ENSMUST00000155650]
|
| AlphaFold |
Q91XL9 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000074352
|
| SMART Domains |
Protein: ENSMUSP00000073957
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
47 |
76 |
2.05e-6 |
SMART |
|
ANK
|
80 |
109 |
1.29e-3 |
SMART |
|
low complexity region
|
141 |
153 |
N/A |
INTRINSIC |
|
ANK
|
175 |
204 |
1.31e-4 |
SMART |
|
PH
|
236 |
336 |
6.02e-8 |
SMART |
|
low complexity region
|
345 |
354 |
N/A |
INTRINSIC |
|
coiled coil region
|
430 |
463 |
N/A |
INTRINSIC |
|
Pfam:Oxysterol_BP
|
548 |
940 |
6.7e-149 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000117361
|
| SMART Domains |
Protein: ENSMUSP00000112681
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000118313
|
| SMART Domains |
Protein: ENSMUSP00000113735
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000119043
|
| SMART Domains |
Protein: ENSMUSP00000113357
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000119512
|
| SMART Domains |
Protein: ENSMUSP00000113914
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
38 |
71 |
N/A |
INTRINSIC |
|
Pfam:Oxysterol_BP
|
156 |
549 |
1.2e-149 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000121774
|
| SMART Domains |
Protein: ENSMUSP00000113268
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
8 |
401 |
4e-150 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000121808
|
| SMART Domains |
Protein: ENSMUSP00000113841
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154614
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000143077
|
| SMART Domains |
Protein: ENSMUSP00000122967
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
184 |
3.5e-69 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000121888
|
| SMART Domains |
Protein: ENSMUSP00000112895
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145777
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155650
|
| SMART Domains |
Protein: ENSMUSP00000120439
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
13 |
46 |
N/A |
INTRINSIC |
|
Pfam:Oxysterol_BP
|
131 |
187 |
1.3e-23 |
PFAM |
|
| Meta Mutation Damage Score |
0.9493 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.8%
|
| Validation Efficiency |
98% (96/98) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930432E11Rik |
A |
T |
7: 29,274,326 (GRCm39) |
|
noncoding transcript |
Het |
| 4933434E20Rik |
A |
G |
3: 89,970,516 (GRCm39) |
N17D |
probably benign |
Het |
| A1bg |
T |
C |
15: 60,792,100 (GRCm39) |
D176G |
probably benign |
Het |
| Abcg5 |
A |
T |
17: 84,966,076 (GRCm39) |
M428K |
possibly damaging |
Het |
| Adam1a |
A |
T |
5: 121,657,752 (GRCm39) |
C514S |
probably damaging |
Het |
| Angptl3 |
A |
G |
4: 98,925,649 (GRCm39) |
Q325R |
probably benign |
Het |
| Ankrd26 |
C |
T |
6: 118,525,811 (GRCm39) |
W378* |
probably null |
Het |
| Apob |
T |
C |
12: 8,065,391 (GRCm39) |
V4087A |
possibly damaging |
Het |
| Auts2 |
A |
G |
5: 131,494,931 (GRCm39) |
I117T |
probably damaging |
Het |
| AW146154 |
T |
A |
7: 41,129,892 (GRCm39) |
E408V |
probably damaging |
Het |
| Bicd1 |
A |
T |
6: 149,385,588 (GRCm39) |
N107I |
probably benign |
Het |
| Blm |
T |
C |
7: 80,159,294 (GRCm39) |
S281G |
probably benign |
Het |
| Btaf1 |
T |
A |
19: 36,979,858 (GRCm39) |
D1542E |
probably benign |
Het |
| C2cd2l |
A |
G |
9: 44,226,442 (GRCm39) |
|
probably null |
Het |
| Capn8 |
C |
A |
1: 182,432,116 (GRCm39) |
N362K |
probably damaging |
Het |
| Ccdc14 |
T |
G |
16: 34,525,408 (GRCm39) |
S186A |
probably damaging |
Het |
| Cdca4 |
A |
G |
12: 112,785,167 (GRCm39) |
L187P |
probably damaging |
Het |
| Chil6 |
T |
A |
3: 106,313,290 (GRCm39) |
K20* |
probably null |
Het |
| Cmss1 |
A |
T |
16: 57,136,545 (GRCm39) |
L109* |
probably null |
Het |
| Cmtm6 |
G |
T |
9: 114,560,410 (GRCm39) |
W36L |
probably benign |
Het |
| Cnksr3 |
T |
G |
10: 7,110,757 (GRCm39) |
I35L |
possibly damaging |
Het |
| Col4a2 |
G |
T |
8: 11,473,570 (GRCm39) |
G534* |
probably null |
Het |
| Col5a1 |
T |
G |
2: 27,915,656 (GRCm39) |
V180G |
probably damaging |
Het |
| Ctnna3 |
T |
C |
10: 63,417,723 (GRCm39) |
F154L |
probably benign |
Het |
| Fabp7 |
G |
A |
10: 57,661,676 (GRCm39) |
V50M |
possibly damaging |
Het |
| Fam170a |
T |
A |
18: 50,415,050 (GRCm39) |
V232D |
probably damaging |
Het |
| Fam186a |
T |
G |
15: 99,843,689 (GRCm39) |
T852P |
unknown |
Het |
| Fam20a |
T |
C |
11: 109,564,389 (GRCm39) |
I455V |
probably benign |
Het |
| Fbxl6 |
C |
T |
15: 76,421,004 (GRCm39) |
V324M |
probably damaging |
Het |
| Galnt18 |
T |
C |
7: 111,378,730 (GRCm39) |
T9A |
probably damaging |
Het |
| Golgb1 |
T |
A |
16: 36,711,769 (GRCm39) |
M191K |
possibly damaging |
Het |
| Gpld1 |
A |
G |
13: 25,166,699 (GRCm39) |
T650A |
probably benign |
Het |
| Gprc5d |
A |
G |
6: 135,093,515 (GRCm39) |
F131L |
probably benign |
Het |
| H2az2 |
C |
T |
11: 6,389,437 (GRCm39) |
G7E |
unknown |
Het |
| Haus4 |
A |
T |
14: 54,783,292 (GRCm39) |
|
probably null |
Het |
| Helq |
A |
G |
5: 100,922,029 (GRCm39) |
I725T |
possibly damaging |
Het |
| Igsf23 |
T |
A |
7: 19,675,755 (GRCm39) |
D117V |
possibly damaging |
Het |
| Kiz |
A |
T |
2: 146,784,008 (GRCm39) |
S514C |
probably damaging |
Het |
| Klhl6 |
A |
T |
16: 19,775,783 (GRCm39) |
N258K |
probably benign |
Het |
| Krt72 |
G |
C |
15: 101,689,508 (GRCm39) |
|
probably null |
Het |
| Large1 |
A |
T |
8: 73,774,975 (GRCm39) |
I245N |
probably damaging |
Het |
| Lrrc31 |
T |
C |
3: 30,733,306 (GRCm39) |
I469M |
probably damaging |
Het |
| Lypd4 |
T |
A |
7: 24,566,121 (GRCm39) |
I68F |
probably benign |
Het |
| Mast1 |
A |
G |
8: 85,650,408 (GRCm39) |
S442P |
probably damaging |
Het |
| Mmp20 |
T |
A |
9: 7,645,300 (GRCm39) |
H283Q |
probably benign |
Het |
| Mrps5 |
G |
A |
2: 127,445,627 (GRCm39) |
V385M |
possibly damaging |
Het |
| Ms4a15 |
T |
C |
19: 10,956,590 (GRCm39) |
K241E |
possibly damaging |
Het |
| Myt1 |
A |
G |
2: 181,439,255 (GRCm39) |
E259G |
probably damaging |
Het |
| Myt1l |
C |
A |
12: 29,945,304 (GRCm39) |
T1023K |
unknown |
Het |
| Ncapd3 |
T |
C |
9: 26,997,342 (GRCm39) |
L1221P |
probably damaging |
Het |
| Ncoa6 |
A |
G |
2: 155,249,053 (GRCm39) |
V1417A |
possibly damaging |
Het |
| Nmnat1 |
A |
G |
4: 149,557,802 (GRCm39) |
V80A |
possibly damaging |
Het |
| Nwd2 |
A |
G |
5: 63,965,189 (GRCm39) |
E1591G |
probably benign |
Het |
| Or10ac1 |
A |
G |
6: 42,515,770 (GRCm39) |
F62S |
probably damaging |
Het |
| Or8j3b |
A |
G |
2: 86,204,853 (GRCm39) |
L301S |
possibly damaging |
Het |
| Papln |
T |
C |
12: 83,821,194 (GRCm39) |
I204T |
probably damaging |
Het |
| Phf1 |
A |
G |
17: 27,153,652 (GRCm39) |
T97A |
probably benign |
Het |
| Plxnb1 |
A |
G |
9: 108,934,442 (GRCm39) |
D890G |
probably damaging |
Het |
| Ppp1r12b |
G |
T |
1: 134,883,471 (GRCm39) |
A17E |
probably benign |
Het |
| Ptgir |
A |
G |
7: 16,640,794 (GRCm39) |
M29V |
possibly damaging |
Het |
| Rbp2 |
G |
A |
9: 98,389,876 (GRCm39) |
C96Y |
probably damaging |
Het |
| Rgmb |
A |
T |
17: 16,027,624 (GRCm39) |
M365K |
possibly damaging |
Het |
| Ric1 |
A |
G |
19: 29,572,936 (GRCm39) |
N792S |
possibly damaging |
Het |
| Ruvbl1 |
T |
C |
6: 88,474,211 (GRCm39) |
Y405H |
possibly damaging |
Het |
| Scaf4 |
A |
G |
16: 90,047,195 (GRCm39) |
M394T |
unknown |
Het |
| Siglech |
T |
A |
7: 55,418,177 (GRCm39) |
C48* |
probably null |
Het |
| Skic2 |
A |
G |
17: 35,061,897 (GRCm39) |
V695A |
possibly damaging |
Het |
| Slc2a5 |
A |
G |
4: 150,224,462 (GRCm39) |
T320A |
probably benign |
Het |
| Slc6a7 |
T |
C |
18: 61,135,277 (GRCm39) |
Y417C |
probably benign |
Het |
| Sox21 |
A |
G |
14: 118,472,336 (GRCm39) |
C238R |
possibly damaging |
Het |
| Tbata |
A |
T |
10: 61,019,132 (GRCm39) |
K109N |
probably damaging |
Het |
| Tecpr2 |
T |
G |
12: 110,921,164 (GRCm39) |
S1246A |
probably benign |
Het |
| Tekt3 |
A |
G |
11: 62,972,085 (GRCm39) |
D247G |
probably benign |
Het |
| Tenm3 |
A |
T |
8: 48,766,271 (GRCm39) |
|
probably null |
Het |
| Thada |
A |
T |
17: 84,748,532 (GRCm39) |
|
probably null |
Het |
| Tpcn2 |
C |
T |
7: 144,826,088 (GRCm39) |
G204R |
probably damaging |
Het |
| Tpm2 |
T |
C |
4: 43,519,220 (GRCm39) |
|
probably null |
Het |
| Trbv24 |
T |
C |
6: 41,195,026 (GRCm39) |
|
probably benign |
Het |
| Tyw1 |
A |
G |
5: 130,305,899 (GRCm39) |
R341G |
probably benign |
Het |
| Vmn1r183 |
T |
G |
7: 23,754,564 (GRCm39) |
N122K |
probably benign |
Het |
| Vmn2r61 |
T |
A |
7: 41,916,459 (GRCm39) |
H357Q |
possibly damaging |
Het |
| Vps13b |
C |
T |
15: 35,869,518 (GRCm39) |
T2674I |
probably damaging |
Het |
| Vps13b |
T |
C |
15: 35,910,439 (GRCm39) |
L3401P |
probably benign |
Het |
| Vps16 |
T |
G |
2: 130,280,220 (GRCm39) |
|
probably benign |
Het |
| Vrtn |
T |
A |
12: 84,696,468 (GRCm39) |
I406N |
probably damaging |
Het |
| Vwa8 |
A |
T |
14: 79,172,053 (GRCm39) |
Y278F |
probably benign |
Het |
| Washc4 |
A |
T |
10: 83,415,376 (GRCm39) |
I789F |
possibly damaging |
Het |
| Zbtb20 |
C |
A |
16: 43,438,761 (GRCm39) |
T627K |
probably damaging |
Het |
| Zfyve16 |
A |
T |
13: 92,658,693 (GRCm39) |
I406K |
probably benign |
Het |
| Zfyve9 |
A |
C |
4: 108,575,195 (GRCm39) |
S629A |
possibly damaging |
Het |
| Zpld1 |
A |
T |
16: 55,068,618 (GRCm39) |
N164K |
probably damaging |
Het |
|
| Other mutations in Osbpl1a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00585:Osbpl1a
|
APN |
18 |
12,890,683 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01062:Osbpl1a
|
APN |
18 |
13,038,132 (GRCm39) |
missense |
probably benign |
|
|
IGL01450:Osbpl1a
|
APN |
18 |
13,004,152 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01531:Osbpl1a
|
APN |
18 |
13,066,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01548:Osbpl1a
|
APN |
18 |
12,896,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01606:Osbpl1a
|
APN |
18 |
12,889,271 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01672:Osbpl1a
|
APN |
18 |
12,899,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02372:Osbpl1a
|
APN |
18 |
12,974,370 (GRCm39) |
nonsense |
probably null |
|
|
IGL02451:Osbpl1a
|
APN |
18 |
13,047,550 (GRCm39) |
splice site |
probably benign |
|
|
IGL02490:Osbpl1a
|
APN |
18 |
13,015,341 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02884:Osbpl1a
|
APN |
18 |
12,952,635 (GRCm39) |
nonsense |
probably null |
|
|
R0084:Osbpl1a
|
UTSW |
18 |
12,890,669 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0266:Osbpl1a
|
UTSW |
18 |
13,004,220 (GRCm39) |
splice site |
probably null |
|
|
R0565:Osbpl1a
|
UTSW |
18 |
12,892,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0605:Osbpl1a
|
UTSW |
18 |
13,015,336 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0899:Osbpl1a
|
UTSW |
18 |
12,890,747 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1330:Osbpl1a
|
UTSW |
18 |
13,015,251 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1464:Osbpl1a
|
UTSW |
18 |
13,047,615 (GRCm39) |
missense |
probably benign |
|
|
R1464:Osbpl1a
|
UTSW |
18 |
13,047,615 (GRCm39) |
missense |
probably benign |
|
|
R1475:Osbpl1a
|
UTSW |
18 |
12,890,737 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1495:Osbpl1a
|
UTSW |
18 |
12,891,896 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1734:Osbpl1a
|
UTSW |
18 |
12,921,373 (GRCm39) |
splice site |
probably null |
|
|
R1930:Osbpl1a
|
UTSW |
18 |
13,038,251 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1931:Osbpl1a
|
UTSW |
18 |
13,038,251 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2109:Osbpl1a
|
UTSW |
18 |
12,892,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2144:Osbpl1a
|
UTSW |
18 |
13,004,230 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2504:Osbpl1a
|
UTSW |
18 |
13,038,088 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2762:Osbpl1a
|
UTSW |
18 |
12,899,956 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R2907:Osbpl1a
|
UTSW |
18 |
13,004,129 (GRCm39) |
unclassified |
probably benign |
|
|
R4306:Osbpl1a
|
UTSW |
18 |
12,952,652 (GRCm39) |
missense |
probably benign |
|
|
R5097:Osbpl1a
|
UTSW |
18 |
12,896,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5173:Osbpl1a
|
UTSW |
18 |
12,895,697 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5224:Osbpl1a
|
UTSW |
18 |
13,066,753 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5245:Osbpl1a
|
UTSW |
18 |
12,891,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5579:Osbpl1a
|
UTSW |
18 |
13,025,319 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5579:Osbpl1a
|
UTSW |
18 |
12,974,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5833:Osbpl1a
|
UTSW |
18 |
12,921,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5986:Osbpl1a
|
UTSW |
18 |
13,038,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6267:Osbpl1a
|
UTSW |
18 |
12,952,560 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6296:Osbpl1a
|
UTSW |
18 |
12,952,560 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6477:Osbpl1a
|
UTSW |
18 |
12,889,318 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6997:Osbpl1a
|
UTSW |
18 |
12,889,281 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7105:Osbpl1a
|
UTSW |
18 |
12,900,020 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7107:Osbpl1a
|
UTSW |
18 |
12,974,310 (GRCm39) |
nonsense |
probably null |
|
|
R7154:Osbpl1a
|
UTSW |
18 |
12,901,649 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7459:Osbpl1a
|
UTSW |
18 |
13,066,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7757:Osbpl1a
|
UTSW |
18 |
13,066,657 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7797:Osbpl1a
|
UTSW |
18 |
13,015,321 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8029:Osbpl1a
|
UTSW |
18 |
13,047,578 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8084:Osbpl1a
|
UTSW |
18 |
13,038,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8506:Osbpl1a
|
UTSW |
18 |
12,901,643 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8947:Osbpl1a
|
UTSW |
18 |
12,899,858 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9069:Osbpl1a
|
UTSW |
18 |
13,002,074 (GRCm39) |
intron |
probably benign |
|
|
R9085:Osbpl1a
|
UTSW |
18 |
13,062,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9288:Osbpl1a
|
UTSW |
18 |
12,904,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9443:Osbpl1a
|
UTSW |
18 |
13,031,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9517:Osbpl1a
|
UTSW |
18 |
13,042,965 (GRCm39) |
missense |
probably benign |
|
|
R9600:Osbpl1a
|
UTSW |
18 |
13,015,277 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9658:Osbpl1a
|
UTSW |
18 |
12,889,269 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9694:Osbpl1a
|
UTSW |
18 |
12,952,565 (GRCm39) |
missense |
probably benign |
0.03 |
|
X0027:Osbpl1a
|
UTSW |
18 |
12,892,560 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
Z1177:Osbpl1a
|
UTSW |
18 |
13,039,980 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCTAGAAGGGTGGGAACTG -3'
(R):5'- ATCCAAACTGATCGAGCCTC -3'
Sequencing Primer
(F):5'- TGGGAACTGAAACACTTGTAATGTG -3'
(R):5'- ACTGATCGAGCCTCTCAATAATCTTG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation