Incidental Mutation 'R4849:Sphkap'
| ID |
373354 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sphkap
|
| Ensembl Gene |
ENSMUSG00000026163 |
| Gene Name |
SPHK1 interactor, AKAP domain containing |
| Synonyms |
SKIP, A930009L15Rik, 4930544G21Rik |
| MMRRC Submission |
042461-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.074)
|
| Stock # |
R4849 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
83233163-83385853 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 83255105 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 881
(E881D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124872
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000159078]
[ENSMUST00000160953]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000053075
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159078
AA Change: E594D
PolyPhen 2
Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000124384
Gene: ENSMUSG00000026163
AA Change: E594D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
303 |
314 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
382 |
462 |
5e-3 |
SMART |
|
low complexity region
|
809 |
819 |
N/A |
INTRINSIC |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1221 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1254 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1281 |
1398 |
7.5e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160953
AA Change: E881D
PolyPhen 2
Score 0.033 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000124872
Gene: ENSMUSG00000026163
AA Change: E881D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
590 |
601 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
669 |
749 |
6e-3 |
SMART |
|
low complexity region
|
1096 |
1106 |
N/A |
INTRINSIC |
|
low complexity region
|
1141 |
1152 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1508 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1540 |
1655 |
6.4e-12 |
PFAM |
|
| Meta Mutation Damage Score |
0.1152 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.2%
|
| Validation Efficiency |
98% (90/92) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acp7 |
G |
T |
7: 28,314,877 (GRCm39) |
R239S |
possibly damaging |
Het |
| Angptl1 |
C |
A |
1: 156,684,735 (GRCm39) |
N301K |
probably benign |
Het |
| Ankrd26 |
T |
A |
6: 118,509,257 (GRCm39) |
T603S |
probably benign |
Het |
| App |
T |
C |
16: 84,853,322 (GRCm39) |
D252G |
unknown |
Het |
| Atxn3 |
A |
G |
12: 101,900,627 (GRCm39) |
S219P |
probably benign |
Het |
| Birc6 |
T |
C |
17: 74,954,383 (GRCm39) |
S3397P |
probably damaging |
Het |
| Bivm |
A |
G |
1: 44,182,033 (GRCm39) |
I414V |
possibly damaging |
Het |
| Cemip |
A |
G |
7: 83,584,945 (GRCm39) |
F1324L |
possibly damaging |
Het |
| Ckap5 |
T |
A |
2: 91,445,616 (GRCm39) |
N1724K |
probably damaging |
Het |
| Corin |
T |
A |
5: 72,460,178 (GRCm39) |
M1035L |
probably damaging |
Het |
| Ctnna3 |
T |
C |
10: 64,709,094 (GRCm39) |
I711T |
probably damaging |
Het |
| Cts6 |
A |
T |
13: 61,349,415 (GRCm39) |
W98R |
probably null |
Het |
| Dip2a |
A |
G |
10: 76,130,367 (GRCm39) |
S580P |
probably damaging |
Het |
| Dock6 |
A |
G |
9: 21,723,068 (GRCm39) |
|
probably null |
Het |
| Dusp15 |
T |
A |
2: 152,791,002 (GRCm39) |
T32S |
probably damaging |
Het |
| Eogt |
T |
A |
6: 97,093,016 (GRCm39) |
N387I |
probably damaging |
Het |
| Evx2 |
T |
C |
2: 74,489,675 (GRCm39) |
D29G |
probably benign |
Het |
| Fat1 |
A |
G |
8: 45,466,007 (GRCm39) |
N1422S |
probably benign |
Het |
| Fat2 |
T |
C |
11: 55,201,463 (GRCm39) |
D537G |
probably damaging |
Het |
| Fat3 |
A |
C |
9: 16,289,244 (GRCm39) |
I93S |
probably benign |
Het |
| Fem1b |
T |
C |
9: 62,704,576 (GRCm39) |
E228G |
probably damaging |
Het |
| Fh1 |
A |
G |
1: 175,448,072 (GRCm39) |
T25A |
probably benign |
Het |
| Fndc3b |
A |
G |
3: 27,514,097 (GRCm39) |
W695R |
probably damaging |
Het |
| Gaa |
G |
A |
11: 119,163,813 (GRCm39) |
V222I |
possibly damaging |
Het |
| Ggnbp1 |
T |
C |
17: 27,251,947 (GRCm39) |
|
probably null |
Het |
| Gipc1 |
A |
G |
8: 84,388,756 (GRCm39) |
Y154C |
probably benign |
Het |
| Gm5356 |
G |
T |
8: 89,913,670 (GRCm39) |
|
noncoding transcript |
Het |
| Gnl1 |
T |
A |
17: 36,298,603 (GRCm39) |
|
probably null |
Het |
| Gpcpd1 |
C |
T |
2: 132,376,019 (GRCm39) |
G605R |
probably damaging |
Het |
| Guca1a |
T |
C |
17: 47,705,662 (GRCm39) |
T177A |
possibly damaging |
Het |
| Ifit1bl1 |
T |
C |
19: 34,572,076 (GRCm39) |
E127G |
probably damaging |
Het |
| Ift81 |
A |
T |
5: 122,729,282 (GRCm39) |
I350N |
probably damaging |
Het |
| Ikbke |
GCC |
G |
1: 131,203,004 (GRCm39) |
|
probably null |
Het |
| Ing4 |
A |
G |
6: 125,020,946 (GRCm39) |
R23G |
probably damaging |
Het |
| Ins1 |
A |
G |
19: 52,253,384 (GRCm39) |
N108S |
probably damaging |
Het |
| Iqce |
A |
T |
5: 140,679,214 (GRCm39) |
M72K |
possibly damaging |
Het |
| Itga3 |
C |
A |
11: 94,967,097 (GRCm39) |
M22I |
probably benign |
Het |
| Kctd18 |
T |
C |
1: 58,001,152 (GRCm39) |
E201G |
probably damaging |
Het |
| Klc1 |
A |
G |
12: 111,748,129 (GRCm39) |
N344S |
probably damaging |
Het |
| Klrb1f |
A |
T |
6: 129,033,347 (GRCm39) |
I192F |
probably damaging |
Het |
| Klrg2 |
A |
T |
6: 38,607,214 (GRCm39) |
|
probably null |
Het |
| Kntc1 |
A |
C |
5: 123,897,128 (GRCm39) |
I164L |
probably benign |
Het |
| Ltf |
T |
A |
9: 110,855,058 (GRCm39) |
I357K |
probably benign |
Het |
| Mr1 |
T |
C |
1: 155,006,436 (GRCm39) |
T304A |
probably benign |
Het |
| Msh6 |
C |
T |
17: 88,290,947 (GRCm39) |
R178C |
possibly damaging |
Het |
| Mtch1 |
T |
C |
17: 29,566,565 (GRCm39) |
D66G |
probably benign |
Het |
| Mtmr7 |
A |
G |
8: 41,062,040 (GRCm39) |
V15A |
probably benign |
Het |
| Mtss2 |
A |
T |
8: 111,452,875 (GRCm39) |
H40L |
possibly damaging |
Het |
| Mxra8 |
A |
G |
4: 155,925,331 (GRCm39) |
|
probably benign |
Het |
| Myo3b |
T |
C |
2: 70,075,253 (GRCm39) |
L535P |
probably damaging |
Het |
| Neurl2 |
T |
A |
2: 164,674,739 (GRCm39) |
|
probably null |
Het |
| Nfia |
A |
C |
4: 97,970,048 (GRCm39) |
T503P |
probably damaging |
Het |
| Noa1 |
T |
C |
5: 77,454,179 (GRCm39) |
E487G |
possibly damaging |
Het |
| Nuak1 |
A |
T |
10: 84,211,143 (GRCm39) |
V315D |
probably damaging |
Het |
| Nup205 |
A |
G |
6: 35,207,505 (GRCm39) |
N1519S |
possibly damaging |
Het |
| Or10x1 |
T |
A |
1: 174,196,966 (GRCm39) |
I161K |
probably damaging |
Het |
| Or1l4b |
T |
C |
2: 37,036,266 (GRCm39) |
L14P |
probably damaging |
Het |
| Or1o1 |
T |
C |
17: 37,716,589 (GRCm39) |
V50A |
probably benign |
Het |
| Or51f1e |
A |
G |
7: 102,747,526 (GRCm39) |
I193V |
possibly damaging |
Het |
| Or6b13 |
G |
T |
7: 139,782,340 (GRCm39) |
C114* |
probably null |
Het |
| Or9s18 |
G |
A |
13: 65,300,493 (GRCm39) |
V152M |
possibly damaging |
Het |
| Peli1 |
T |
A |
11: 21,098,528 (GRCm39) |
|
probably benign |
Het |
| Ppp6r1 |
A |
G |
7: 4,646,206 (GRCm39) |
L175P |
probably damaging |
Het |
| Prkcd |
A |
G |
14: 30,321,700 (GRCm39) |
L498P |
probably damaging |
Het |
| Prss30 |
T |
A |
17: 24,191,769 (GRCm39) |
I251F |
probably benign |
Het |
| Psme3 |
A |
T |
11: 101,207,907 (GRCm39) |
N21Y |
probably benign |
Het |
| Ptpra |
T |
C |
2: 130,374,081 (GRCm39) |
Y271H |
probably damaging |
Het |
| Ralgapa1 |
T |
A |
12: 55,745,588 (GRCm39) |
N1303Y |
probably damaging |
Het |
| Rims4 |
T |
C |
2: 163,707,463 (GRCm39) |
I121V |
probably benign |
Het |
| Rnf123 |
A |
T |
9: 107,933,290 (GRCm39) |
L1149Q |
probably damaging |
Het |
| Ryr3 |
T |
A |
2: 112,738,807 (GRCm39) |
L593F |
probably damaging |
Het |
| Sec23b |
T |
C |
2: 144,427,519 (GRCm39) |
F582S |
probably damaging |
Het |
| Sgpl1 |
T |
C |
10: 60,940,297 (GRCm39) |
K335R |
probably benign |
Het |
| Sirpa |
C |
T |
2: 129,451,163 (GRCm39) |
T141I |
probably damaging |
Het |
| Slit1 |
G |
T |
19: 41,637,983 (GRCm39) |
A270E |
probably benign |
Het |
| Snap91 |
T |
C |
9: 86,674,613 (GRCm39) |
T533A |
possibly damaging |
Het |
| Sptan1 |
C |
A |
2: 29,901,054 (GRCm39) |
R1407S |
probably damaging |
Het |
| Tfdp1 |
A |
G |
8: 13,423,895 (GRCm39) |
T353A |
probably benign |
Het |
| Ttyh1 |
A |
G |
7: 4,125,533 (GRCm39) |
I62V |
possibly damaging |
Het |
| Vwde |
A |
T |
6: 13,196,047 (GRCm39) |
V326D |
possibly damaging |
Het |
| Zfp398 |
T |
C |
6: 47,836,446 (GRCm39) |
I82T |
possibly damaging |
Het |
| Zp1 |
A |
G |
19: 10,896,198 (GRCm39) |
Y176H |
possibly damaging |
Het |
|
| Other mutations in Sphkap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00332:Sphkap
|
APN |
1 |
83,258,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00337:Sphkap
|
APN |
1 |
83,317,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00470:Sphkap
|
APN |
1 |
83,255,631 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL00577:Sphkap
|
APN |
1 |
83,256,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00657:Sphkap
|
APN |
1 |
83,254,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01868:Sphkap
|
APN |
1 |
83,258,120 (GRCm39) |
splice site |
probably null |
|
|
IGL02101:Sphkap
|
APN |
1 |
83,268,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02471:Sphkap
|
APN |
1 |
83,253,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02945:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03008:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03031:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03059:Sphkap
|
APN |
1 |
83,234,963 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03085:Sphkap
|
APN |
1 |
83,258,075 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03355:Sphkap
|
APN |
1 |
83,258,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03356:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03368:Sphkap
|
APN |
1 |
83,253,397 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0294:Sphkap
|
UTSW |
1 |
83,255,966 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0308:Sphkap
|
UTSW |
1 |
83,254,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0478:Sphkap
|
UTSW |
1 |
83,256,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Sphkap
|
UTSW |
1 |
83,258,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0678:Sphkap
|
UTSW |
1 |
83,256,349 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1216:Sphkap
|
UTSW |
1 |
83,268,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1253:Sphkap
|
UTSW |
1 |
83,256,619 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1532:Sphkap
|
UTSW |
1 |
83,234,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Sphkap
|
UTSW |
1 |
83,256,121 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1655:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1657:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1700:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1701:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1734:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1736:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1743:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1744:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1760:Sphkap
|
UTSW |
1 |
83,255,265 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1893:Sphkap
|
UTSW |
1 |
83,256,687 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1937:Sphkap
|
UTSW |
1 |
83,245,162 (GRCm39) |
nonsense |
probably null |
|
|
R1986:Sphkap
|
UTSW |
1 |
83,255,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1993:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1995:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R2001:Sphkap
|
UTSW |
1 |
83,254,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2004:Sphkap
|
UTSW |
1 |
83,255,632 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2111:Sphkap
|
UTSW |
1 |
83,253,602 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2112:Sphkap
|
UTSW |
1 |
83,253,602 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2156:Sphkap
|
UTSW |
1 |
83,255,710 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2182:Sphkap
|
UTSW |
1 |
83,254,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Sphkap
|
UTSW |
1 |
83,234,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Sphkap
|
UTSW |
1 |
83,254,833 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3919:Sphkap
|
UTSW |
1 |
83,254,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3980:Sphkap
|
UTSW |
1 |
83,245,215 (GRCm39) |
splice site |
probably null |
|
|
R4130:Sphkap
|
UTSW |
1 |
83,255,619 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4539:Sphkap
|
UTSW |
1 |
83,255,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4602:Sphkap
|
UTSW |
1 |
83,256,782 (GRCm39) |
nonsense |
probably null |
|
|
R4735:Sphkap
|
UTSW |
1 |
83,256,838 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4793:Sphkap
|
UTSW |
1 |
83,255,805 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4880:Sphkap
|
UTSW |
1 |
83,266,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5213:Sphkap
|
UTSW |
1 |
83,258,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5277:Sphkap
|
UTSW |
1 |
83,253,885 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5331:Sphkap
|
UTSW |
1 |
83,254,503 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5632:Sphkap
|
UTSW |
1 |
83,256,006 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5647:Sphkap
|
UTSW |
1 |
83,385,720 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5751:Sphkap
|
UTSW |
1 |
83,253,618 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5935:Sphkap
|
UTSW |
1 |
83,317,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5999:Sphkap
|
UTSW |
1 |
83,245,126 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6232:Sphkap
|
UTSW |
1 |
83,258,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Sphkap
|
UTSW |
1 |
83,256,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Sphkap
|
UTSW |
1 |
83,256,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6602:Sphkap
|
UTSW |
1 |
83,253,479 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6674:Sphkap
|
UTSW |
1 |
83,255,555 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6716:Sphkap
|
UTSW |
1 |
83,339,949 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6803:Sphkap
|
UTSW |
1 |
83,258,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6880:Sphkap
|
UTSW |
1 |
83,234,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6941:Sphkap
|
UTSW |
1 |
83,385,811 (GRCm39) |
start gained |
probably benign |
|
|
R7170:Sphkap
|
UTSW |
1 |
83,243,706 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7263:Sphkap
|
UTSW |
1 |
83,254,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7422:Sphkap
|
UTSW |
1 |
83,241,547 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7640:Sphkap
|
UTSW |
1 |
83,256,649 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7722:Sphkap
|
UTSW |
1 |
83,256,642 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7810:Sphkap
|
UTSW |
1 |
83,254,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7887:Sphkap
|
UTSW |
1 |
83,255,133 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7974:Sphkap
|
UTSW |
1 |
83,256,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7990:Sphkap
|
UTSW |
1 |
83,245,066 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8096:Sphkap
|
UTSW |
1 |
83,255,279 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8110:Sphkap
|
UTSW |
1 |
83,256,492 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8125:Sphkap
|
UTSW |
1 |
83,241,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Sphkap
|
UTSW |
1 |
83,255,730 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8245:Sphkap
|
UTSW |
1 |
83,256,492 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8394:Sphkap
|
UTSW |
1 |
83,253,797 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8443:Sphkap
|
UTSW |
1 |
83,255,953 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8508:Sphkap
|
UTSW |
1 |
83,254,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8531:Sphkap
|
UTSW |
1 |
83,254,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Sphkap
|
UTSW |
1 |
83,253,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8674:Sphkap
|
UTSW |
1 |
83,255,565 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8682:Sphkap
|
UTSW |
1 |
83,256,997 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8837:Sphkap
|
UTSW |
1 |
83,253,384 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8857:Sphkap
|
UTSW |
1 |
83,258,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8902:Sphkap
|
UTSW |
1 |
83,256,685 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8916:Sphkap
|
UTSW |
1 |
83,255,108 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8944:Sphkap
|
UTSW |
1 |
83,256,927 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9154:Sphkap
|
UTSW |
1 |
83,234,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9579:Sphkap
|
UTSW |
1 |
83,255,295 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9616:Sphkap
|
UTSW |
1 |
83,254,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9781:Sphkap
|
UTSW |
1 |
83,255,772 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,256,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,254,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,258,163 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,253,754 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Sphkap
|
UTSW |
1 |
83,254,152 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATTGGAGTTGTCAAGGCAG -3'
(R):5'- CTGCTAAGTCATTCCCCAAGG -3'
Sequencing Primer
(F):5'- CAGATTGCTGCAATTTCAGTTG -3'
(R):5'- TCCCCAAGGAAATATATCTGAAAGG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation