Incidental Mutation 'R4852:Atp4a'
| ID |
373625 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atp4a
|
| Ensembl Gene |
ENSMUSG00000005553 |
| Gene Name |
ATPase, H+/K+ exchanging, gastric, alpha polypeptide |
| Synonyms |
H+K+-transporting alpha 1, H+/K+-ATPase alpha |
| MMRRC Submission |
042464-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.098)
|
| Stock # |
R4852 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
30411634-30424959 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 30423693 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Threonine
at position 933
(A933T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131964
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000005692]
[ENSMUST00000006478]
[ENSMUST00000170371]
[ENSMUST00000171014]
[ENSMUST00000207263]
[ENSMUST00000207296]
[ENSMUST00000209065]
[ENSMUST00000208169]
[ENSMUST00000207779]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000005692
AA Change: A942T
PolyPhen 2
Score 0.103 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000005692
Gene: ENSMUSG00000005553
AA Change: A942T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:H-K_ATPase_N
|
2 |
42 |
5.4e-23 |
PFAM |
|
Cation_ATPase_N
|
52 |
126 |
2.26e-18 |
SMART |
|
Pfam:E1-E2_ATPase
|
144 |
375 |
1.1e-57 |
PFAM |
|
Pfam:Hydrolase
|
380 |
739 |
5.3e-16 |
PFAM |
|
Pfam:HAD
|
383 |
736 |
1.9e-18 |
PFAM |
|
Pfam:Cation_ATPase
|
436 |
531 |
1.6e-24 |
PFAM |
|
Pfam:Cation_ATPase_C
|
809 |
1019 |
4.8e-43 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000006478
|
| SMART Domains |
Protein: ENSMUSP00000006478
Gene: ENSMUSG00000006315
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2053
|
2 |
158 |
3.1e-69 |
PFAM |
|
transmembrane domain
|
168 |
190 |
N/A |
INTRINSIC |
|
transmembrane domain
|
197 |
219 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000165410
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000167761
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170371
AA Change: A933T
PolyPhen 2
Score 0.103 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000131964
Gene: ENSMUSG00000005553
AA Change: A933T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:H-K_ATPase_N
|
2 |
42 |
4.9e-28 |
PFAM |
|
Cation_ATPase_N
|
52 |
126 |
2.26e-18 |
SMART |
|
Pfam:E1-E2_ATPase
|
145 |
376 |
1e-62 |
PFAM |
|
Pfam:Hydrolase
|
380 |
730 |
9.3e-25 |
PFAM |
|
Pfam:HAD
|
383 |
727 |
2.1e-15 |
PFAM |
|
Pfam:Hydrolase_like2
|
436 |
531 |
4e-25 |
PFAM |
|
Pfam:Cation_ATPase_C
|
800 |
1010 |
1.5e-42 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171014
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207263
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207296
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000209065
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208169
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207779
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000207955
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.2%
- 20x: 92.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous mutation of this gene results in achlorhydria, hypergastrinemia, and abnormalities of the parietal cells. Mice homozygous for an ENU-induced allele exhibit iron-deficiency anemia. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(3) : Targeted, knock-out(1) Targeted, other(2) |
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
G |
T |
12: 71,211,320 (GRCm39) |
E685* |
probably null |
Het |
| 2700049A03Rik |
A |
T |
12: 71,211,321 (GRCm39) |
E685V |
possibly damaging |
Het |
| 4921524L21Rik |
C |
G |
18: 6,623,487 (GRCm39) |
L66V |
possibly damaging |
Het |
| 4921524L21Rik |
T |
A |
18: 6,623,488 (GRCm39) |
L66Q |
probably damaging |
Het |
| Abca6 |
A |
G |
11: 110,135,029 (GRCm39) |
V252A |
probably benign |
Het |
| Ablim2 |
C |
T |
5: 35,959,766 (GRCm39) |
R73C |
possibly damaging |
Het |
| Acap1 |
C |
T |
11: 69,775,202 (GRCm39) |
V354M |
probably benign |
Het |
| Accs |
T |
C |
2: 93,674,605 (GRCm39) |
D99G |
probably damaging |
Het |
| Adam9 |
T |
C |
8: 25,493,317 (GRCm39) |
Y97C |
probably damaging |
Het |
| Akap6 |
T |
C |
12: 53,151,458 (GRCm39) |
V1174A |
probably damaging |
Het |
| Aknad1 |
C |
A |
3: 108,659,056 (GRCm39) |
D23E |
probably damaging |
Het |
| Ano2 |
T |
C |
6: 125,959,886 (GRCm39) |
C666R |
possibly damaging |
Het |
| Atxn2 |
T |
C |
5: 121,952,474 (GRCm39) |
L224P |
probably damaging |
Het |
| Bin2 |
T |
C |
15: 100,543,169 (GRCm39) |
E338G |
probably damaging |
Het |
| Bloc1s5 |
T |
C |
13: 38,818,960 (GRCm39) |
K20E |
probably damaging |
Het |
| Bst1 |
A |
T |
5: 43,977,867 (GRCm39) |
D72V |
probably benign |
Het |
| Cacna1i |
T |
C |
15: 80,272,680 (GRCm39) |
F1631L |
probably damaging |
Het |
| Capn13 |
GCA |
G |
17: 73,658,501 (GRCm39) |
|
probably null |
Het |
| Cfap43 |
A |
G |
19: 47,885,550 (GRCm39) |
I355T |
possibly damaging |
Het |
| Chuk |
A |
T |
19: 44,077,197 (GRCm39) |
M383K |
possibly damaging |
Het |
| Cnga4 |
A |
G |
7: 105,054,937 (GRCm39) |
I174V |
probably benign |
Het |
| Cpd |
T |
C |
11: 76,675,976 (GRCm39) |
K1226E |
probably benign |
Het |
| Crip2 |
T |
C |
12: 113,104,204 (GRCm39) |
C5R |
probably damaging |
Het |
| Cyp3a11 |
T |
A |
5: 145,797,305 (GRCm39) |
D358V |
probably damaging |
Het |
| Ebag9 |
T |
C |
15: 44,487,915 (GRCm39) |
F21S |
probably damaging |
Het |
| Ercc1 |
A |
T |
7: 19,084,629 (GRCm39) |
H70L |
probably damaging |
Het |
| Exoc3 |
G |
A |
13: 74,347,764 (GRCm39) |
R69C |
probably damaging |
Het |
| Fgfr4 |
A |
T |
13: 55,308,969 (GRCm39) |
R363S |
possibly damaging |
Het |
| Gas2l3 |
CACTCGTCATACT |
CACT |
10: 89,266,820 (GRCm39) |
|
probably benign |
Het |
| Gm7489 |
T |
A |
15: 53,749,434 (GRCm39) |
|
probably benign |
Het |
| Gphn |
G |
A |
12: 78,673,984 (GRCm39) |
V526M |
probably damaging |
Het |
| Gpr152 |
G |
A |
19: 4,193,790 (GRCm39) |
V444I |
probably benign |
Het |
| Gss |
T |
C |
2: 155,406,785 (GRCm39) |
E330G |
probably benign |
Het |
| Hbs1l |
A |
G |
10: 21,234,287 (GRCm39) |
D556G |
possibly damaging |
Het |
| Helz2 |
T |
C |
2: 180,871,913 (GRCm39) |
T2619A |
probably damaging |
Het |
| Hk3 |
A |
G |
13: 55,160,409 (GRCm39) |
F304L |
probably damaging |
Het |
| Itgad |
A |
T |
7: 127,797,702 (GRCm39) |
N906Y |
probably damaging |
Het |
| Jakmip2 |
T |
C |
18: 43,710,465 (GRCm39) |
E246G |
probably damaging |
Het |
| L3mbtl4 |
A |
T |
17: 68,866,748 (GRCm39) |
H329L |
probably damaging |
Het |
| Mau2 |
A |
G |
8: 70,485,827 (GRCm39) |
|
probably null |
Het |
| Myo16 |
T |
C |
8: 10,423,474 (GRCm39) |
L270P |
probably damaging |
Het |
| Naa25 |
T |
C |
5: 121,568,755 (GRCm39) |
S606P |
probably damaging |
Het |
| Nags |
T |
A |
11: 102,037,447 (GRCm39) |
C179* |
probably null |
Het |
| Naip2 |
A |
G |
13: 100,298,044 (GRCm39) |
M664T |
probably benign |
Het |
| Ndufv3 |
T |
C |
17: 31,747,043 (GRCm39) |
I311T |
probably benign |
Het |
| Nipsnap1 |
G |
T |
11: 4,841,468 (GRCm39) |
E258* |
probably null |
Het |
| Nudc |
A |
G |
4: 133,261,660 (GRCm39) |
L208P |
probably damaging |
Het |
| Or1e32 |
T |
C |
11: 73,705,074 (GRCm39) |
Y278C |
probably benign |
Het |
| Or51a39 |
A |
T |
7: 102,362,750 (GRCm39) |
V290E |
probably damaging |
Het |
| Oscp1 |
A |
G |
4: 125,970,652 (GRCm39) |
D137G |
possibly damaging |
Het |
| Pcdhb5 |
C |
T |
18: 37,455,524 (GRCm39) |
P635S |
probably benign |
Het |
| Pcdhgb2 |
T |
A |
18: 37,825,103 (GRCm39) |
I698N |
probably damaging |
Het |
| Pde4b |
A |
G |
4: 102,454,967 (GRCm39) |
Y399C |
probably damaging |
Het |
| Pdf |
A |
T |
8: 107,774,812 (GRCm39) |
V140E |
probably damaging |
Het |
| Pglyrp2 |
T |
C |
17: 32,634,823 (GRCm39) |
N513S |
probably benign |
Het |
| Ranbp2 |
T |
A |
10: 58,312,878 (GRCm39) |
D1199E |
possibly damaging |
Het |
| Rell2 |
G |
T |
18: 38,089,621 (GRCm39) |
|
probably null |
Het |
| Rgl2 |
A |
G |
17: 34,156,147 (GRCm39) |
H745R |
probably benign |
Het |
| Rnf121 |
A |
G |
7: 101,672,592 (GRCm39) |
C264R |
probably damaging |
Het |
| Rnf181 |
A |
G |
6: 72,338,499 (GRCm39) |
F3S |
probably damaging |
Het |
| Rsrc1 |
T |
A |
3: 67,262,935 (GRCm39) |
D296E |
probably damaging |
Het |
| Rubcn |
A |
T |
16: 32,663,678 (GRCm39) |
D319E |
probably damaging |
Het |
| Scaf8 |
T |
C |
17: 3,228,494 (GRCm39) |
S431P |
unknown |
Het |
| Septin11 |
T |
A |
5: 93,310,112 (GRCm39) |
M305K |
possibly damaging |
Het |
| Serpinb12 |
A |
G |
1: 106,884,132 (GRCm39) |
K293E |
probably benign |
Het |
| Sh3bp1 |
T |
A |
15: 78,788,538 (GRCm39) |
H229Q |
probably benign |
Het |
| Slco4c1 |
G |
A |
1: 96,768,953 (GRCm39) |
P303L |
probably damaging |
Het |
| Specc1 |
T |
A |
11: 62,102,510 (GRCm39) |
V952E |
probably damaging |
Het |
| Spint2 |
G |
A |
7: 28,956,211 (GRCm39) |
T158I |
probably benign |
Het |
| St8sia4 |
A |
T |
1: 95,588,623 (GRCm39) |
W71R |
probably damaging |
Het |
| Tex48 |
C |
T |
4: 63,530,151 (GRCm39) |
V23I |
possibly damaging |
Het |
| Tmc5 |
G |
A |
7: 118,244,562 (GRCm39) |
G480D |
probably benign |
Het |
| Tmem8b |
T |
A |
4: 43,689,713 (GRCm39) |
M330K |
probably damaging |
Het |
| Tnrc18 |
C |
T |
5: 142,717,095 (GRCm39) |
R2453Q |
probably damaging |
Het |
| Trank1 |
A |
T |
9: 111,220,963 (GRCm39) |
N2567Y |
possibly damaging |
Het |
| Trps1 |
T |
C |
15: 50,709,705 (GRCm39) |
D211G |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,555,503 (GRCm39) |
R30501G |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,573,247 (GRCm39) |
Y25882F |
probably damaging |
Het |
| Unc79 |
T |
A |
12: 103,139,725 (GRCm39) |
V2495E |
probably damaging |
Het |
| Uqcr10 |
T |
A |
11: 4,652,198 (GRCm39) |
H58L |
possibly damaging |
Het |
| Usp7 |
A |
T |
16: 8,574,708 (GRCm39) |
C58* |
probably null |
Het |
| Vmn1r36 |
A |
T |
6: 66,693,872 (GRCm39) |
M1K |
probably null |
Het |
| Wdr7 |
T |
A |
18: 63,911,020 (GRCm39) |
M804K |
probably damaging |
Het |
| Zfp131 |
A |
C |
13: 120,250,394 (GRCm39) |
|
probably null |
Het |
| Zfp507 |
A |
G |
7: 35,493,480 (GRCm39) |
V521A |
probably benign |
Het |
|
| Other mutations in Atp4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00339:Atp4a
|
APN |
7 |
30,412,629 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01327:Atp4a
|
APN |
7 |
30,412,675 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01510:Atp4a
|
APN |
7 |
30,420,216 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01763:Atp4a
|
APN |
7 |
30,414,943 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL02061:Atp4a
|
APN |
7 |
30,414,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02435:Atp4a
|
APN |
7 |
30,416,482 (GRCm39) |
missense |
probably benign |
|
|
IGL02903:Atp4a
|
APN |
7 |
30,415,344 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03181:Atp4a
|
APN |
7 |
30,424,129 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03350:Atp4a
|
APN |
7 |
30,420,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
atypical
|
UTSW |
7 |
30,414,781 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
sublytic
|
UTSW |
7 |
30,415,225 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03097:Atp4a
|
UTSW |
7 |
30,422,462 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0095:Atp4a
|
UTSW |
7 |
30,420,160 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0121:Atp4a
|
UTSW |
7 |
30,419,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0140:Atp4a
|
UTSW |
7 |
30,419,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0241:Atp4a
|
UTSW |
7 |
30,416,560 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0437:Atp4a
|
UTSW |
7 |
30,419,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0624:Atp4a
|
UTSW |
7 |
30,418,424 (GRCm39) |
missense |
probably benign |
|
|
R1164:Atp4a
|
UTSW |
7 |
30,417,117 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2105:Atp4a
|
UTSW |
7 |
30,419,793 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2272:Atp4a
|
UTSW |
7 |
30,414,925 (GRCm39) |
nonsense |
probably null |
|
|
R2327:Atp4a
|
UTSW |
7 |
30,419,666 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2881:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2990:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2992:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2993:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3123:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3125:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3441:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3442:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3686:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3687:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3845:Atp4a
|
UTSW |
7 |
30,416,540 (GRCm39) |
missense |
probably null |
0.99 |
|
R4027:Atp4a
|
UTSW |
7 |
30,424,377 (GRCm39) |
splice site |
probably null |
|
|
R4072:Atp4a
|
UTSW |
7 |
30,414,757 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4433:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4454:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4457:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4458:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4510:Atp4a
|
UTSW |
7 |
30,423,678 (GRCm39) |
nonsense |
probably null |
|
|
R4511:Atp4a
|
UTSW |
7 |
30,423,678 (GRCm39) |
nonsense |
probably null |
|
|
R4576:Atp4a
|
UTSW |
7 |
30,417,147 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4656:Atp4a
|
UTSW |
7 |
30,419,373 (GRCm39) |
intron |
probably benign |
|
|
R4661:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4662:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4892:Atp4a
|
UTSW |
7 |
30,411,899 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4907:Atp4a
|
UTSW |
7 |
30,418,517 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5024:Atp4a
|
UTSW |
7 |
30,415,289 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5254:Atp4a
|
UTSW |
7 |
30,414,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5318:Atp4a
|
UTSW |
7 |
30,414,754 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5340:Atp4a
|
UTSW |
7 |
30,420,231 (GRCm39) |
missense |
probably benign |
|
|
R5484:Atp4a
|
UTSW |
7 |
30,420,097 (GRCm39) |
unclassified |
probably benign |
|
|
R5729:Atp4a
|
UTSW |
7 |
30,411,851 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5762:Atp4a
|
UTSW |
7 |
30,418,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5797:Atp4a
|
UTSW |
7 |
30,412,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Atp4a
|
UTSW |
7 |
30,421,941 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6030:Atp4a
|
UTSW |
7 |
30,421,941 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6077:Atp4a
|
UTSW |
7 |
30,415,344 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6243:Atp4a
|
UTSW |
7 |
30,415,382 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6346:Atp4a
|
UTSW |
7 |
30,414,781 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6459:Atp4a
|
UTSW |
7 |
30,411,887 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6515:Atp4a
|
UTSW |
7 |
30,411,903 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6773:Atp4a
|
UTSW |
7 |
30,414,802 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6854:Atp4a
|
UTSW |
7 |
30,414,433 (GRCm39) |
missense |
probably benign |
0.29 |
|
R7215:Atp4a
|
UTSW |
7 |
30,416,785 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7271:Atp4a
|
UTSW |
7 |
30,421,944 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7340:Atp4a
|
UTSW |
7 |
30,416,155 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7457:Atp4a
|
UTSW |
7 |
30,420,192 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7593:Atp4a
|
UTSW |
7 |
30,424,105 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7712:Atp4a
|
UTSW |
7 |
30,414,978 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7762:Atp4a
|
UTSW |
7 |
30,419,461 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8714:Atp4a
|
UTSW |
7 |
30,420,013 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9324:Atp4a
|
UTSW |
7 |
30,415,207 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Atp4a
|
UTSW |
7 |
30,417,265 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
Z1186:Atp4a
|
UTSW |
7 |
30,416,782 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TAAGCCCCTCTAAATGCTGGG -3'
(R):5'- AGGCCATATTTCCATGGTTTGTAAC -3'
Sequencing Primer
(F):5'- CCTCTAAATGCTGGGGTCCTG -3'
(R):5'- GTTTGTAACCAGCTCACAACATG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation