Incidental Mutation 'R4863:N4bp2'
| ID |
374638 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
N4bp2
|
| Ensembl Gene |
ENSMUSG00000037795 |
| Gene Name |
NEDD4 binding protein 2 |
| Synonyms |
B3bp, LOC333789, LOC386488 |
| MMRRC Submission |
042473-MU
|
| Accession Numbers |
Genbank: NM_001024917.1; Ensembl: ENSMUST00000113738
|
| Essential gene? |
Probably non essential
(E-score: 0.140)
|
| Stock # |
R4863 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
65763521-65830108 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 65808130 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1174
(V1174A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144278
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087264]
[ENSMUST00000201489]
[ENSMUST00000201615]
|
| AlphaFold |
F8VQG7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000087264
AA Change: V1174A
PolyPhen 2
Score 0.225 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000084519
Gene: ENSMUSG00000037795
AA Change: V1174A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1.1e-15 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200843
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201489
AA Change: V1174A
PolyPhen 2
Score 0.225 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000143807
Gene: ENSMUSG00000037795
AA Change: V1174A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201615
AA Change: V1174A
PolyPhen 2
Score 0.225 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000144278
Gene: ENSMUSG00000037795
AA Change: V1174A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1.2e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
8e-10 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202411
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.2%
|
| Validation Efficiency |
99% (105/106) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
|
| Allele List at MGI |
All alleles(9) : Targeted, other(2) Gene trapped(7)
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210407C18Rik |
A |
T |
11: 58,612,512 |
|
probably null |
Het |
| 4930578I06Rik |
C |
T |
14: 63,973,209 |
R190H |
probably benign |
Het |
| A530032D15Rik |
C |
T |
1: 85,088,800 |
|
probably benign |
Het |
| Abcc12 |
T |
A |
8: 86,538,376 |
I647F |
probably damaging |
Het |
| Acnat2 |
C |
A |
4: 49,380,172 |
W384L |
probably damaging |
Het |
| Acvr1 |
A |
G |
2: 58,477,711 |
L146P |
possibly damaging |
Het |
| Ankrd16 |
T |
A |
2: 11,784,316 |
M238K |
probably benign |
Het |
| BC005561 |
A |
T |
5: 104,517,750 |
D46V |
possibly damaging |
Het |
| Cd3eap |
T |
A |
7: 19,357,759 |
Q141L |
probably damaging |
Het |
| Clmn |
A |
T |
12: 104,797,094 |
I91N |
probably damaging |
Het |
| Cog8 |
A |
T |
8: 107,050,174 |
L523H |
probably damaging |
Het |
| Cpxm2 |
T |
A |
7: 132,059,747 |
K437M |
probably benign |
Het |
| Dhx57 |
A |
T |
17: 80,253,111 |
V999E |
probably damaging |
Het |
| Dnpep |
T |
C |
1: 75,309,230 |
|
probably benign |
Het |
| Dok3 |
G |
A |
13: 55,523,457 |
R434W |
probably damaging |
Het |
| Dpysl5 |
C |
T |
5: 30,784,343 |
H275Y |
probably benign |
Het |
| Ednra |
A |
T |
8: 77,667,383 |
N361K |
probably damaging |
Het |
| Ei24 |
A |
T |
9: 36,784,565 |
S210R |
probably damaging |
Het |
| Erich3 |
T |
A |
3: 154,764,804 |
V158E |
unknown |
Het |
| Fam193a |
T |
A |
5: 34,466,205 |
V1379E |
possibly damaging |
Het |
| Fasn |
A |
G |
11: 120,808,828 |
V2304A |
probably damaging |
Het |
| Fcgbp |
A |
C |
7: 28,086,344 |
D402A |
probably benign |
Het |
| Fkbp14 |
T |
C |
6: 54,585,945 |
|
probably benign |
Het |
| Fnip1 |
G |
A |
11: 54,515,556 |
V1160I |
possibly damaging |
Het |
| Fsd2 |
T |
C |
7: 81,552,964 |
K289R |
probably null |
Het |
| Fuca2 |
A |
T |
10: 13,505,907 |
D188V |
probably damaging |
Het |
| Gfpt2 |
T |
C |
11: 49,810,970 |
V116A |
probably benign |
Het |
| Gm10770 |
T |
A |
2: 150,178,896 |
K234* |
probably null |
Het |
| Gm9887 |
A |
G |
12: 69,371,989 |
|
probably benign |
Het |
| Gtf3c2 |
A |
G |
5: 31,159,233 |
|
probably benign |
Het |
| H2-M10.3 |
T |
C |
17: 36,366,636 |
D250G |
probably damaging |
Het |
| Hapln4 |
G |
A |
8: 70,084,492 |
V26M |
possibly damaging |
Het |
| Hook3 |
G |
A |
8: 26,038,029 |
A611V |
probably damaging |
Het |
| Hr |
T |
C |
14: 70,571,972 |
L1141P |
probably damaging |
Het |
| Ifngr1 |
T |
C |
10: 19,609,416 |
S388P |
probably damaging |
Het |
| Itga3 |
T |
A |
11: 95,061,967 |
Q326L |
probably damaging |
Het |
| Itgb3 |
T |
A |
11: 104,665,520 |
I729N |
probably damaging |
Het |
| Kcnab2 |
A |
G |
4: 152,401,946 |
S132P |
probably damaging |
Het |
| Lama3 |
T |
C |
18: 12,498,678 |
|
probably benign |
Het |
| Lama3 |
C |
T |
18: 12,539,793 |
A2481V |
probably damaging |
Het |
| Lce1e |
A |
T |
3: 92,707,871 |
C56* |
probably null |
Het |
| Lmcd1 |
T |
C |
6: 112,287,871 |
|
probably benign |
Het |
| Lrrc14 |
T |
A |
15: 76,713,362 |
|
probably null |
Het |
| Map4k5 |
G |
A |
12: 69,818,438 |
P591L |
probably benign |
Het |
| Mapk13 |
C |
A |
17: 28,776,310 |
D168E |
probably damaging |
Het |
| Marf1 |
A |
C |
16: 14,132,665 |
H952Q |
possibly damaging |
Het |
| Megf6 |
T |
C |
4: 154,254,281 |
|
probably null |
Het |
| Mical3 |
T |
C |
6: 121,033,787 |
I411M |
probably damaging |
Het |
| Myo5a |
A |
T |
9: 75,217,507 |
K1781N |
probably damaging |
Het |
| Ncdn |
A |
T |
4: 126,750,423 |
L202Q |
probably damaging |
Het |
| Ncor1 |
T |
A |
11: 62,392,638 |
M408L |
possibly damaging |
Het |
| Nf1 |
T |
C |
11: 79,409,409 |
L249P |
probably damaging |
Het |
| Nlrp9b |
T |
A |
7: 20,049,596 |
|
probably null |
Het |
| Nxpe3 |
A |
T |
16: 55,849,633 |
Y370N |
probably damaging |
Het |
| P2rx2 |
T |
A |
5: 110,341,568 |
T167S |
probably benign |
Het |
| Pcdhb19 |
G |
T |
18: 37,499,108 |
R652L |
probably benign |
Het |
| Pcdhga12 |
T |
C |
18: 37,768,281 |
L722P |
probably benign |
Het |
| Pde6a |
A |
T |
18: 61,245,592 |
I329F |
probably damaging |
Het |
| Pdpr |
T |
A |
8: 111,101,951 |
S29T |
probably benign |
Het |
| Pfkfb3 |
T |
C |
2: 11,486,312 |
D173G |
probably benign |
Het |
| Plcd4 |
A |
G |
1: 74,565,802 |
|
probably null |
Het |
| Pou2f2 |
A |
G |
7: 25,097,108 |
|
probably benign |
Het |
| Ppp1r14c |
TGGCGGCGGCGGCGGCGG |
TGGCGGCGGCGGCGG |
10: 3,366,702 |
|
probably benign |
Het |
| Ppp1r42 |
T |
C |
1: 10,003,386 |
|
probably benign |
Het |
| Ptpre |
C |
T |
7: 135,669,132 |
H346Y |
probably benign |
Het |
| Ptpro |
T |
A |
6: 137,443,594 |
V1007D |
probably damaging |
Het |
| Rab12 |
A |
T |
17: 66,498,108 |
Y142N |
probably damaging |
Het |
| Rai14 |
A |
C |
15: 10,572,470 |
M857R |
probably damaging |
Het |
| Ranbp2 |
A |
G |
10: 58,492,421 |
K2753R |
probably damaging |
Het |
| Rasa4 |
A |
T |
5: 136,103,911 |
K6* |
probably null |
Het |
| Rasgef1a |
A |
G |
6: 118,089,139 |
M438V |
probably benign |
Het |
| Recql |
T |
G |
6: 142,359,006 |
|
probably benign |
Het |
| Rftn2 |
A |
G |
1: 55,172,039 |
V425A |
probably benign |
Het |
| Ror1 |
A |
G |
4: 100,409,804 |
Y234C |
probably damaging |
Het |
| Sap30l |
T |
A |
11: 57,806,054 |
L70Q |
probably damaging |
Het |
| Scn4a |
T |
C |
11: 106,320,002 |
R1730G |
probably damaging |
Het |
| Serinc5 |
T |
G |
13: 92,690,980 |
I268R |
probably damaging |
Het |
| Sin3b |
G |
A |
8: 72,744,948 |
V432I |
possibly damaging |
Het |
| Slc30a6 |
T |
C |
17: 74,412,654 |
M203T |
possibly damaging |
Het |
| Soat1 |
T |
C |
1: 156,432,328 |
N481S |
probably damaging |
Het |
| Sos2 |
G |
A |
12: 69,640,154 |
T206I |
probably benign |
Het |
| Sp100 |
G |
T |
1: 85,705,003 |
A132S |
probably benign |
Het |
| Spata31d1c |
T |
A |
13: 65,035,790 |
L382* |
probably null |
Het |
| Stard9 |
T |
A |
2: 120,700,860 |
W2533R |
probably benign |
Het |
| Tas2r126 |
A |
G |
6: 42,435,390 |
T286A |
probably benign |
Het |
| Tedc2 |
T |
A |
17: 24,217,936 |
K275M |
probably damaging |
Het |
| Ten1 |
A |
T |
11: 116,218,231 |
K242N |
probably benign |
Het |
| Tial1 |
C |
T |
7: 128,455,028 |
V1I |
probably damaging |
Het |
| Tle2 |
G |
A |
10: 81,588,891 |
R649H |
possibly damaging |
Het |
| Tmem178 |
A |
G |
17: 80,944,945 |
D86G |
probably benign |
Het |
| Trim29 |
T |
A |
9: 43,329,575 |
D528E |
possibly damaging |
Het |
| Vmn2r61 |
A |
T |
7: 42,300,708 |
T851S |
probably benign |
Het |
| Vmn2r72 |
T |
A |
7: 85,750,598 |
Q414H |
possibly damaging |
Het |
| Yars |
A |
T |
4: 129,189,882 |
|
probably benign |
Het |
| Yipf4 |
A |
G |
17: 74,494,092 |
Q135R |
probably damaging |
Het |
| Zfp341 |
G |
A |
2: 154,645,866 |
|
probably benign |
Het |
| Zfp426 |
T |
C |
9: 20,470,038 |
Y536C |
probably damaging |
Het |
| Zp2 |
T |
G |
7: 120,135,772 |
Y430S |
probably damaging |
Het |
|
| Other mutations in N4bp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:N4bp2
|
APN |
5 |
65,807,524 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01503:N4bp2
|
APN |
5 |
65,803,547 (GRCm38) |
nonsense |
probably null |
0.00 |
|
IGL01621:N4bp2
|
APN |
5 |
65,790,924 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02109:N4bp2
|
APN |
5 |
65,798,134 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02286:N4bp2
|
APN |
5 |
65,803,552 (GRCm38) |
missense |
probably damaging |
1.00 |
|
1mM(1):N4bp2
|
UTSW |
5 |
65,807,677 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03046:N4bp2
|
UTSW |
5 |
65,790,960 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0164:N4bp2
|
UTSW |
5 |
65,803,573 (GRCm38) |
splice site |
probably benign |
|
|
R0285:N4bp2
|
UTSW |
5 |
65,806,559 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0366:N4bp2
|
UTSW |
5 |
65,806,396 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R0548:N4bp2
|
UTSW |
5 |
65,808,153 (GRCm38) |
missense |
probably benign |
0.39 |
|
R0551:N4bp2
|
UTSW |
5 |
65,820,341 (GRCm38) |
splice site |
probably null |
|
|
R0671:N4bp2
|
UTSW |
5 |
65,807,437 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1136:N4bp2
|
UTSW |
5 |
65,808,472 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1515:N4bp2
|
UTSW |
5 |
65,790,498 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1597:N4bp2
|
UTSW |
5 |
65,807,140 (GRCm38) |
missense |
probably benign |
0.45 |
|
R1628:N4bp2
|
UTSW |
5 |
65,803,572 (GRCm38) |
splice site |
probably null |
|
|
R1722:N4bp2
|
UTSW |
5 |
65,806,882 (GRCm38) |
missense |
probably benign |
0.08 |
|
R1735:N4bp2
|
UTSW |
5 |
65,808,316 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1745:N4bp2
|
UTSW |
5 |
65,790,822 (GRCm38) |
missense |
probably benign |
0.12 |
|
R1759:N4bp2
|
UTSW |
5 |
65,826,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1799:N4bp2
|
UTSW |
5 |
65,806,825 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R1846:N4bp2
|
UTSW |
5 |
65,808,519 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1872:N4bp2
|
UTSW |
5 |
65,794,518 (GRCm38) |
splice site |
probably benign |
|
|
R2042:N4bp2
|
UTSW |
5 |
65,826,621 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2082:N4bp2
|
UTSW |
5 |
65,807,565 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2101:N4bp2
|
UTSW |
5 |
65,790,881 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2147:N4bp2
|
UTSW |
5 |
65,809,200 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2251:N4bp2
|
UTSW |
5 |
65,806,728 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2507:N4bp2
|
UTSW |
5 |
65,790,061 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2508:N4bp2
|
UTSW |
5 |
65,790,061 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2919:N4bp2
|
UTSW |
5 |
65,807,098 (GRCm38) |
missense |
probably benign |
0.22 |
|
R3086:N4bp2
|
UTSW |
5 |
65,791,053 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4092:N4bp2
|
UTSW |
5 |
65,790,456 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4177:N4bp2
|
UTSW |
5 |
65,798,170 (GRCm38) |
splice site |
probably null |
|
|
R4718:N4bp2
|
UTSW |
5 |
65,803,463 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4859:N4bp2
|
UTSW |
5 |
65,825,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4915:N4bp2
|
UTSW |
5 |
65,803,504 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4949:N4bp2
|
UTSW |
5 |
65,821,799 (GRCm38) |
splice site |
probably null |
|
|
R4978:N4bp2
|
UTSW |
5 |
65,790,240 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5029:N4bp2
|
UTSW |
5 |
65,814,780 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5079:N4bp2
|
UTSW |
5 |
65,811,977 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5097:N4bp2
|
UTSW |
5 |
65,817,218 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5158:N4bp2
|
UTSW |
5 |
65,808,462 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5228:N4bp2
|
UTSW |
5 |
65,807,518 (GRCm38) |
missense |
probably benign |
|
|
R5322:N4bp2
|
UTSW |
5 |
65,790,457 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R5554:N4bp2
|
UTSW |
5 |
65,808,114 (GRCm38) |
missense |
probably benign |
0.44 |
|
R5731:N4bp2
|
UTSW |
5 |
65,809,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5840:N4bp2
|
UTSW |
5 |
65,808,094 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6393:N4bp2
|
UTSW |
5 |
65,791,001 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R6767:N4bp2
|
UTSW |
5 |
65,817,187 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7103:N4bp2
|
UTSW |
5 |
65,806,846 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7112:N4bp2
|
UTSW |
5 |
65,790,707 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R7171:N4bp2
|
UTSW |
5 |
65,808,022 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7177:N4bp2
|
UTSW |
5 |
65,807,548 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7240:N4bp2
|
UTSW |
5 |
65,794,545 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7353:N4bp2
|
UTSW |
5 |
65,806,371 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7450:N4bp2
|
UTSW |
5 |
65,825,300 (GRCm38) |
nonsense |
probably null |
|
|
R7560:N4bp2
|
UTSW |
5 |
65,791,115 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7698:N4bp2
|
UTSW |
5 |
65,808,157 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7743:N4bp2
|
UTSW |
5 |
65,808,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7871:N4bp2
|
UTSW |
5 |
65,807,103 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7981:N4bp2
|
UTSW |
5 |
65,812,142 (GRCm38) |
missense |
probably benign |
0.41 |
|
R8065:N4bp2
|
UTSW |
5 |
65,807,296 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8067:N4bp2
|
UTSW |
5 |
65,807,296 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8164:N4bp2
|
UTSW |
5 |
65,809,223 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8166:N4bp2
|
UTSW |
5 |
65,820,312 (GRCm38) |
missense |
probably benign |
0.39 |
|
R8331:N4bp2
|
UTSW |
5 |
65,807,600 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8559:N4bp2
|
UTSW |
5 |
65,825,285 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R8806:N4bp2
|
UTSW |
5 |
65,808,208 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R9287:N4bp2
|
UTSW |
5 |
65,803,512 (GRCm38) |
missense |
probably benign |
0.38 |
|
R9369:N4bp2
|
UTSW |
5 |
65,806,916 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9460:N4bp2
|
UTSW |
5 |
65,806,543 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9462:N4bp2
|
UTSW |
5 |
65,790,555 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9605:N4bp2
|
UTSW |
5 |
65,806,536 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9641:N4bp2
|
UTSW |
5 |
65,790,692 (GRCm38) |
missense |
probably benign |
0.15 |
|
Z1177:N4bp2
|
UTSW |
5 |
65,807,637 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTATGAATCCTGAAAACCCTG -3'
(R):5'- CCAACCACTTCCTGGCATTAG -3'
Sequencing Primer
(F):5'- GCTGCTGTAAAGGTCAAG -3'
(R):5'- AACCACTTCCTGGCATTAGATTTTTC -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation