Incidental Mutation 'R4863:Marf1'
| ID |
374698 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Marf1
|
| Ensembl Gene |
ENSMUSG00000060657 |
| Gene Name |
meiosis regulator and mRNA stability 1 |
| Synonyms |
4921513D23Rik |
| MMRRC Submission |
042473-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.222)
|
| Stock # |
R4863 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
13927030-13977157 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 13950529 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 952
(H952Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000087770
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000090300]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000090300
AA Change: H952Q
PolyPhen 2
Score 0.601 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000087770
Gene: ENSMUSG00000060657
AA Change: H952Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
116 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
290 |
305 |
N/A |
INTRINSIC |
|
Pfam:NYN
|
351 |
492 |
1.5e-21 |
PFAM |
|
RRM
|
511 |
579 |
3.17e-1 |
SMART |
|
low complexity region
|
599 |
610 |
N/A |
INTRINSIC |
|
RRM
|
790 |
864 |
4.47e-3 |
SMART |
|
internal_repeat_2
|
871 |
914 |
1.57e-5 |
PROSPERO |
|
low complexity region
|
944 |
960 |
N/A |
INTRINSIC |
|
Pfam:OST-HTH
|
1096 |
1167 |
1e-11 |
PFAM |
|
low complexity region
|
1181 |
1186 |
N/A |
INTRINSIC |
|
Pfam:OST-HTH
|
1256 |
1328 |
1.2e-10 |
PFAM |
|
Pfam:OST-HTH
|
1332 |
1404 |
2.4e-10 |
PFAM |
|
Pfam:OST-HTH
|
1408 |
1480 |
6.8e-13 |
PFAM |
|
Pfam:OST-HTH
|
1483 |
1555 |
3e-14 |
PFAM |
|
low complexity region
|
1682 |
1701 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183739
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.2%
|
| Validation Efficiency |
99% (105/106) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. In humans, it may be autoantigenic. [provided by RefSeq, Jul 2010]
PHENOTYPE: Mice homozygous for an ENU-induced mutation exhibit female infertility with abnormalities in oogenic processes including meiotic progression, genomic integrity and acquisition of developmental competence. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930578I06Rik |
C |
T |
14: 64,210,658 (GRCm39) |
R190H |
probably benign |
Het |
| Abcc12 |
T |
A |
8: 87,265,005 (GRCm39) |
I647F |
probably damaging |
Het |
| Acnat2 |
C |
A |
4: 49,380,172 (GRCm39) |
W384L |
probably damaging |
Het |
| Acvr1 |
A |
G |
2: 58,367,723 (GRCm39) |
L146P |
possibly damaging |
Het |
| Ankrd16 |
T |
A |
2: 11,789,127 (GRCm39) |
M238K |
probably benign |
Het |
| Clmn |
A |
T |
12: 104,763,353 (GRCm39) |
I91N |
probably damaging |
Het |
| Cog8 |
A |
T |
8: 107,776,806 (GRCm39) |
L523H |
probably damaging |
Het |
| Cpxm2 |
T |
A |
7: 131,661,476 (GRCm39) |
K437M |
probably benign |
Het |
| Dhx57 |
A |
T |
17: 80,560,540 (GRCm39) |
V999E |
probably damaging |
Het |
| Dnpep |
T |
C |
1: 75,285,874 (GRCm39) |
|
probably benign |
Het |
| Dok3 |
G |
A |
13: 55,671,270 (GRCm39) |
R434W |
probably damaging |
Het |
| Dpysl5 |
C |
T |
5: 30,941,687 (GRCm39) |
H275Y |
probably benign |
Het |
| Ednra |
A |
T |
8: 78,394,012 (GRCm39) |
N361K |
probably damaging |
Het |
| Ei24 |
A |
T |
9: 36,695,861 (GRCm39) |
S210R |
probably damaging |
Het |
| Erich3 |
T |
A |
3: 154,470,441 (GRCm39) |
V158E |
unknown |
Het |
| Fam193a |
T |
A |
5: 34,623,549 (GRCm39) |
V1379E |
possibly damaging |
Het |
| Fasn |
A |
G |
11: 120,699,654 (GRCm39) |
V2304A |
probably damaging |
Het |
| Fcgbp |
A |
C |
7: 27,785,769 (GRCm39) |
D402A |
probably benign |
Het |
| Fkbp14 |
T |
C |
6: 54,562,930 (GRCm39) |
|
probably benign |
Het |
| Fnip1 |
G |
A |
11: 54,406,382 (GRCm39) |
V1160I |
possibly damaging |
Het |
| Fsd2 |
T |
C |
7: 81,202,712 (GRCm39) |
K289R |
probably null |
Het |
| Fuca2 |
A |
T |
10: 13,381,651 (GRCm39) |
D188V |
probably damaging |
Het |
| Gfpt2 |
T |
C |
11: 49,701,797 (GRCm39) |
V116A |
probably benign |
Het |
| Gm10770 |
T |
A |
2: 150,020,816 (GRCm39) |
K234* |
probably null |
Het |
| Gm9887 |
A |
G |
12: 69,418,763 (GRCm39) |
|
probably benign |
Het |
| Gtf3c2 |
A |
G |
5: 31,316,577 (GRCm39) |
|
probably benign |
Het |
| H2-M10.3 |
T |
C |
17: 36,677,528 (GRCm39) |
D250G |
probably damaging |
Het |
| Hapln4 |
G |
A |
8: 70,537,142 (GRCm39) |
V26M |
possibly damaging |
Het |
| Hook3 |
G |
A |
8: 26,528,057 (GRCm39) |
A611V |
probably damaging |
Het |
| Hr |
T |
C |
14: 70,809,412 (GRCm39) |
L1141P |
probably damaging |
Het |
| Ifngr1 |
T |
C |
10: 19,485,164 (GRCm39) |
S388P |
probably damaging |
Het |
| Itga3 |
T |
A |
11: 94,952,793 (GRCm39) |
Q326L |
probably damaging |
Het |
| Itgb3 |
T |
A |
11: 104,556,346 (GRCm39) |
I729N |
probably damaging |
Het |
| Kcnab2 |
A |
G |
4: 152,486,403 (GRCm39) |
S132P |
probably damaging |
Het |
| Lama3 |
C |
T |
18: 12,672,850 (GRCm39) |
A2481V |
probably damaging |
Het |
| Lama3 |
T |
C |
18: 12,631,735 (GRCm39) |
|
probably benign |
Het |
| Lce1e |
A |
T |
3: 92,615,178 (GRCm39) |
C56* |
probably null |
Het |
| Lmcd1 |
T |
C |
6: 112,264,832 (GRCm39) |
|
probably benign |
Het |
| Lrrc14 |
T |
A |
15: 76,597,562 (GRCm39) |
|
probably null |
Het |
| Lypd8l |
A |
T |
11: 58,503,338 (GRCm39) |
|
probably null |
Het |
| Map4k5 |
G |
A |
12: 69,865,212 (GRCm39) |
P591L |
probably benign |
Het |
| Mapk13 |
C |
A |
17: 28,995,284 (GRCm39) |
D168E |
probably damaging |
Het |
| Megf6 |
T |
C |
4: 154,338,738 (GRCm39) |
|
probably null |
Het |
| Mical3 |
T |
C |
6: 121,010,748 (GRCm39) |
I411M |
probably damaging |
Het |
| Myo5a |
A |
T |
9: 75,124,789 (GRCm39) |
K1781N |
probably damaging |
Het |
| N4bp2 |
T |
C |
5: 65,965,473 (GRCm39) |
V1174A |
probably benign |
Het |
| Ncdn |
A |
T |
4: 126,644,216 (GRCm39) |
L202Q |
probably damaging |
Het |
| Ncor1 |
T |
A |
11: 62,283,464 (GRCm39) |
M408L |
possibly damaging |
Het |
| Nf1 |
T |
C |
11: 79,300,235 (GRCm39) |
L249P |
probably damaging |
Het |
| Nlrp9b |
T |
A |
7: 19,783,521 (GRCm39) |
|
probably null |
Het |
| Nxpe3 |
A |
T |
16: 55,669,996 (GRCm39) |
Y370N |
probably damaging |
Het |
| P2rx2 |
T |
A |
5: 110,489,434 (GRCm39) |
T167S |
probably benign |
Het |
| Pcdhb19 |
G |
T |
18: 37,632,161 (GRCm39) |
R652L |
probably benign |
Het |
| Pcdhga12 |
T |
C |
18: 37,901,334 (GRCm39) |
L722P |
probably benign |
Het |
| Pde6a |
A |
T |
18: 61,378,663 (GRCm39) |
I329F |
probably damaging |
Het |
| Pdpr |
T |
A |
8: 111,828,583 (GRCm39) |
S29T |
probably benign |
Het |
| Pfkfb3 |
T |
C |
2: 11,491,123 (GRCm39) |
D173G |
probably benign |
Het |
| Plcd4 |
A |
G |
1: 74,604,961 (GRCm39) |
|
probably null |
Het |
| Polr1g |
T |
A |
7: 19,091,684 (GRCm39) |
Q141L |
probably damaging |
Het |
| Pou2f2 |
A |
G |
7: 24,796,533 (GRCm39) |
|
probably benign |
Het |
| Ppp1r14c |
TGGCGGCGGCGGCGGCGG |
TGGCGGCGGCGGCGG |
10: 3,316,702 (GRCm39) |
|
probably benign |
Het |
| Ppp1r42 |
T |
C |
1: 10,073,611 (GRCm39) |
|
probably benign |
Het |
| Ptpre |
C |
T |
7: 135,270,861 (GRCm39) |
H346Y |
probably benign |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Rab12 |
A |
T |
17: 66,805,103 (GRCm39) |
Y142N |
probably damaging |
Het |
| Rai14 |
A |
C |
15: 10,572,556 (GRCm39) |
M857R |
probably damaging |
Het |
| Ranbp2 |
A |
G |
10: 58,328,243 (GRCm39) |
K2753R |
probably damaging |
Het |
| Rasa4 |
A |
T |
5: 136,132,765 (GRCm39) |
K6* |
probably null |
Het |
| Rasgef1a |
A |
G |
6: 118,066,100 (GRCm39) |
M438V |
probably benign |
Het |
| Recql |
T |
G |
6: 142,304,732 (GRCm39) |
|
probably benign |
Het |
| Rftn2 |
A |
G |
1: 55,211,198 (GRCm39) |
V425A |
probably benign |
Het |
| Ror1 |
A |
G |
4: 100,267,001 (GRCm39) |
Y234C |
probably damaging |
Het |
| Sap30l |
T |
A |
11: 57,696,880 (GRCm39) |
L70Q |
probably damaging |
Het |
| Scn4a |
T |
C |
11: 106,210,828 (GRCm39) |
R1730G |
probably damaging |
Het |
| Serinc5 |
T |
G |
13: 92,827,488 (GRCm39) |
I268R |
probably damaging |
Het |
| Sin3b |
G |
A |
8: 73,471,576 (GRCm39) |
V432I |
possibly damaging |
Het |
| Slc30a6 |
T |
C |
17: 74,719,649 (GRCm39) |
M203T |
possibly damaging |
Het |
| Soat1 |
T |
C |
1: 156,259,898 (GRCm39) |
N481S |
probably damaging |
Het |
| Sos2 |
G |
A |
12: 69,686,928 (GRCm39) |
T206I |
probably benign |
Het |
| Sp100 |
G |
T |
1: 85,632,724 (GRCm39) |
A132S |
probably benign |
Het |
| Sp140l1 |
C |
T |
1: 85,066,521 (GRCm39) |
|
probably benign |
Het |
| Spata31d1c |
T |
A |
13: 65,183,604 (GRCm39) |
L382* |
probably null |
Het |
| Stard9 |
T |
A |
2: 120,531,341 (GRCm39) |
W2533R |
probably benign |
Het |
| Tas2r126 |
A |
G |
6: 42,412,324 (GRCm39) |
T286A |
probably benign |
Het |
| Tedc2 |
T |
A |
17: 24,436,910 (GRCm39) |
K275M |
probably damaging |
Het |
| Ten1 |
A |
T |
11: 116,109,057 (GRCm39) |
K242N |
probably benign |
Het |
| Thoc2l |
A |
T |
5: 104,665,616 (GRCm39) |
D46V |
possibly damaging |
Het |
| Tial1 |
C |
T |
7: 128,056,752 (GRCm39) |
V1I |
probably damaging |
Het |
| Tle2 |
G |
A |
10: 81,424,725 (GRCm39) |
R649H |
possibly damaging |
Het |
| Tmem178 |
A |
G |
17: 81,252,374 (GRCm39) |
D86G |
probably benign |
Het |
| Trim29 |
T |
A |
9: 43,240,872 (GRCm39) |
D528E |
possibly damaging |
Het |
| Vmn2r61 |
A |
T |
7: 41,950,132 (GRCm39) |
T851S |
probably benign |
Het |
| Vmn2r72 |
T |
A |
7: 85,399,806 (GRCm39) |
Q414H |
possibly damaging |
Het |
| Yars1 |
A |
T |
4: 129,083,675 (GRCm39) |
|
probably benign |
Het |
| Yipf4 |
A |
G |
17: 74,801,087 (GRCm39) |
Q135R |
probably damaging |
Het |
| Zfp341 |
G |
A |
2: 154,487,786 (GRCm39) |
|
probably benign |
Het |
| Zfp426 |
T |
C |
9: 20,381,334 (GRCm39) |
Y536C |
probably damaging |
Het |
| Zp2 |
T |
G |
7: 119,734,995 (GRCm39) |
Y430S |
probably damaging |
Het |
|
| Other mutations in Marf1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00517:Marf1
|
APN |
16 |
13,933,606 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL00933:Marf1
|
APN |
16 |
13,935,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01101:Marf1
|
APN |
16 |
13,964,600 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02140:Marf1
|
APN |
16 |
13,959,776 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03196:Marf1
|
APN |
16 |
13,958,123 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
PIT4283001:Marf1
|
UTSW |
16 |
13,946,432 (GRCm39) |
missense |
probably benign |
0.22 |
|
R0016:Marf1
|
UTSW |
16 |
13,970,129 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0016:Marf1
|
UTSW |
16 |
13,970,129 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0046:Marf1
|
UTSW |
16 |
13,929,591 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R0046:Marf1
|
UTSW |
16 |
13,929,591 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R0056:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0057:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0058:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0058:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0113:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0115:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0179:Marf1
|
UTSW |
16 |
13,969,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0238:Marf1
|
UTSW |
16 |
13,969,147 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0238:Marf1
|
UTSW |
16 |
13,969,147 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0294:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0295:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0316:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0318:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0375:Marf1
|
UTSW |
16 |
13,969,184 (GRCm39) |
splice site |
probably benign |
|
|
R0383:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0391:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0589:Marf1
|
UTSW |
16 |
13,959,919 (GRCm39) |
splice site |
probably benign |
|
|
R0603:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0610:Marf1
|
UTSW |
16 |
13,960,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1240:Marf1
|
UTSW |
16 |
13,964,626 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1445:Marf1
|
UTSW |
16 |
13,933,688 (GRCm39) |
missense |
probably benign |
|
|
R1716:Marf1
|
UTSW |
16 |
13,960,450 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1921:Marf1
|
UTSW |
16 |
13,946,465 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R2098:Marf1
|
UTSW |
16 |
13,932,064 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2155:Marf1
|
UTSW |
16 |
13,950,293 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2177:Marf1
|
UTSW |
16 |
13,970,471 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2195:Marf1
|
UTSW |
16 |
13,929,563 (GRCm39) |
missense |
probably benign |
|
|
R2410:Marf1
|
UTSW |
16 |
13,933,691 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2999:Marf1
|
UTSW |
16 |
13,960,505 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R3000:Marf1
|
UTSW |
16 |
13,960,505 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R3147:Marf1
|
UTSW |
16 |
13,943,843 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R3148:Marf1
|
UTSW |
16 |
13,943,843 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R3430:Marf1
|
UTSW |
16 |
13,958,041 (GRCm39) |
unclassified |
probably benign |
|
|
R3821:Marf1
|
UTSW |
16 |
13,960,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4383:Marf1
|
UTSW |
16 |
13,960,505 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R4384:Marf1
|
UTSW |
16 |
13,960,505 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R4520:Marf1
|
UTSW |
16 |
13,950,530 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4554:Marf1
|
UTSW |
16 |
13,971,841 (GRCm39) |
start gained |
probably benign |
|
|
R4557:Marf1
|
UTSW |
16 |
13,971,841 (GRCm39) |
start gained |
probably benign |
|
|
R4768:Marf1
|
UTSW |
16 |
13,949,461 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4784:Marf1
|
UTSW |
16 |
13,970,321 (GRCm39) |
missense |
probably benign |
|
|
R4857:Marf1
|
UTSW |
16 |
13,946,475 (GRCm39) |
nonsense |
probably null |
|
|
R4994:Marf1
|
UTSW |
16 |
13,932,095 (GRCm39) |
missense |
probably benign |
|
|
R5191:Marf1
|
UTSW |
16 |
13,963,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5503:Marf1
|
UTSW |
16 |
13,970,095 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5813:Marf1
|
UTSW |
16 |
13,970,449 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5905:Marf1
|
UTSW |
16 |
13,945,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5960:Marf1
|
UTSW |
16 |
13,970,281 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6104:Marf1
|
UTSW |
16 |
13,935,319 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6387:Marf1
|
UTSW |
16 |
13,959,504 (GRCm39) |
makesense |
probably null |
|
|
R6533:Marf1
|
UTSW |
16 |
13,933,663 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6608:Marf1
|
UTSW |
16 |
13,950,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6642:Marf1
|
UTSW |
16 |
13,950,611 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6954:Marf1
|
UTSW |
16 |
13,956,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6994:Marf1
|
UTSW |
16 |
13,946,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7010:Marf1
|
UTSW |
16 |
13,954,865 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7090:Marf1
|
UTSW |
16 |
13,929,566 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7174:Marf1
|
UTSW |
16 |
13,954,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7221:Marf1
|
UTSW |
16 |
13,960,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7247:Marf1
|
UTSW |
16 |
13,944,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7557:Marf1
|
UTSW |
16 |
13,950,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7798:Marf1
|
UTSW |
16 |
13,956,315 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7807:Marf1
|
UTSW |
16 |
13,971,753 (GRCm39) |
nonsense |
probably null |
|
|
R7855:Marf1
|
UTSW |
16 |
13,932,065 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7867:Marf1
|
UTSW |
16 |
13,946,470 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7893:Marf1
|
UTSW |
16 |
13,964,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8291:Marf1
|
UTSW |
16 |
13,950,432 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8746:Marf1
|
UTSW |
16 |
13,935,168 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8842:Marf1
|
UTSW |
16 |
13,935,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9253:Marf1
|
UTSW |
16 |
13,935,172 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9350:Marf1
|
UTSW |
16 |
13,963,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9440:Marf1
|
UTSW |
16 |
13,938,196 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9460:Marf1
|
UTSW |
16 |
13,947,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9658:Marf1
|
UTSW |
16 |
13,958,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9698:Marf1
|
UTSW |
16 |
13,967,077 (GRCm39) |
missense |
probably benign |
0.00 |
|
U24488:Marf1
|
UTSW |
16 |
13,950,230 (GRCm39) |
nonsense |
probably null |
|
|
X0025:Marf1
|
UTSW |
16 |
13,932,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Marf1
|
UTSW |
16 |
13,933,641 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAACAGTGAGCTGACTGACTTC -3'
(R):5'- GGGAAAGCCATTCTGTGTTGTC -3'
Sequencing Primer
(F):5'- CTTCTCAGGAGTGGAAAGCATTC -3'
(R):5'- CTGTGTTGTCTTATTAAACAGGTCAG -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation