Incidental Mutation 'R4863:Dhx57'
| ID |
374705 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dhx57
|
| Ensembl Gene |
ENSMUSG00000035051 |
| Gene Name |
DExH-box helicase 57 |
| Synonyms |
|
| MMRRC Submission |
042473-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.171)
|
| Stock # |
R4863 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
80545733-80597620 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 80560540 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 999
(V999E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000083742
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038166]
[ENSMUST00000086555]
|
| AlphaFold |
Q6P5D3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000038166
AA Change: V946E
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000041069
Gene: ENSMUSG00000035051
AA Change: V946E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
116 |
125 |
N/A |
INTRINSIC |
|
UBA
|
129 |
166 |
1.04e-3 |
SMART |
|
ZnF_C3H1
|
246 |
272 |
4.07e-6 |
SMART |
|
low complexity region
|
357 |
368 |
N/A |
INTRINSIC |
|
low complexity region
|
381 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
423 |
432 |
N/A |
INTRINSIC |
|
DEXDc
|
490 |
678 |
1.27e-28 |
SMART |
|
Blast:DEXDc
|
688 |
752 |
2e-28 |
BLAST |
|
HELICc
|
810 |
918 |
3.22e-16 |
SMART |
|
HA2
|
984 |
1074 |
1.64e-24 |
SMART |
|
Pfam:OB_NTP_bind
|
1113 |
1262 |
1.5e-20 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000086555
AA Change: V999E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000083742
Gene: ENSMUSG00000035051
AA Change: V999E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
178 |
N/A |
INTRINSIC |
|
UBA
|
182 |
219 |
1.04e-3 |
SMART |
|
ZnF_C3H1
|
299 |
325 |
4.07e-6 |
SMART |
|
low complexity region
|
410 |
421 |
N/A |
INTRINSIC |
|
low complexity region
|
434 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
476 |
485 |
N/A |
INTRINSIC |
|
DEXDc
|
543 |
731 |
1.27e-28 |
SMART |
|
Blast:DEXDc
|
741 |
805 |
1e-28 |
BLAST |
|
HELICc
|
863 |
971 |
3.22e-16 |
SMART |
|
HA2
|
1037 |
1127 |
1.64e-24 |
SMART |
|
Pfam:OB_NTP_bind
|
1166 |
1315 |
8.5e-25 |
PFAM |
|
| Meta Mutation Damage Score |
0.6027 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.2%
|
| Validation Efficiency |
99% (105/106) |
| Allele List at MGI |
All alleles(25) : Gene trapped(25)
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930578I06Rik |
C |
T |
14: 64,210,658 (GRCm39) |
R190H |
probably benign |
Het |
| Abcc12 |
T |
A |
8: 87,265,005 (GRCm39) |
I647F |
probably damaging |
Het |
| Acnat2 |
C |
A |
4: 49,380,172 (GRCm39) |
W384L |
probably damaging |
Het |
| Acvr1 |
A |
G |
2: 58,367,723 (GRCm39) |
L146P |
possibly damaging |
Het |
| Ankrd16 |
T |
A |
2: 11,789,127 (GRCm39) |
M238K |
probably benign |
Het |
| Clmn |
A |
T |
12: 104,763,353 (GRCm39) |
I91N |
probably damaging |
Het |
| Cog8 |
A |
T |
8: 107,776,806 (GRCm39) |
L523H |
probably damaging |
Het |
| Cpxm2 |
T |
A |
7: 131,661,476 (GRCm39) |
K437M |
probably benign |
Het |
| Dnpep |
T |
C |
1: 75,285,874 (GRCm39) |
|
probably benign |
Het |
| Dok3 |
G |
A |
13: 55,671,270 (GRCm39) |
R434W |
probably damaging |
Het |
| Dpysl5 |
C |
T |
5: 30,941,687 (GRCm39) |
H275Y |
probably benign |
Het |
| Ednra |
A |
T |
8: 78,394,012 (GRCm39) |
N361K |
probably damaging |
Het |
| Ei24 |
A |
T |
9: 36,695,861 (GRCm39) |
S210R |
probably damaging |
Het |
| Erich3 |
T |
A |
3: 154,470,441 (GRCm39) |
V158E |
unknown |
Het |
| Fam193a |
T |
A |
5: 34,623,549 (GRCm39) |
V1379E |
possibly damaging |
Het |
| Fasn |
A |
G |
11: 120,699,654 (GRCm39) |
V2304A |
probably damaging |
Het |
| Fcgbp |
A |
C |
7: 27,785,769 (GRCm39) |
D402A |
probably benign |
Het |
| Fkbp14 |
T |
C |
6: 54,562,930 (GRCm39) |
|
probably benign |
Het |
| Fnip1 |
G |
A |
11: 54,406,382 (GRCm39) |
V1160I |
possibly damaging |
Het |
| Fsd2 |
T |
C |
7: 81,202,712 (GRCm39) |
K289R |
probably null |
Het |
| Fuca2 |
A |
T |
10: 13,381,651 (GRCm39) |
D188V |
probably damaging |
Het |
| Gfpt2 |
T |
C |
11: 49,701,797 (GRCm39) |
V116A |
probably benign |
Het |
| Gm10770 |
T |
A |
2: 150,020,816 (GRCm39) |
K234* |
probably null |
Het |
| Gm9887 |
A |
G |
12: 69,418,763 (GRCm39) |
|
probably benign |
Het |
| Gtf3c2 |
A |
G |
5: 31,316,577 (GRCm39) |
|
probably benign |
Het |
| H2-M10.3 |
T |
C |
17: 36,677,528 (GRCm39) |
D250G |
probably damaging |
Het |
| Hapln4 |
G |
A |
8: 70,537,142 (GRCm39) |
V26M |
possibly damaging |
Het |
| Hook3 |
G |
A |
8: 26,528,057 (GRCm39) |
A611V |
probably damaging |
Het |
| Hr |
T |
C |
14: 70,809,412 (GRCm39) |
L1141P |
probably damaging |
Het |
| Ifngr1 |
T |
C |
10: 19,485,164 (GRCm39) |
S388P |
probably damaging |
Het |
| Itga3 |
T |
A |
11: 94,952,793 (GRCm39) |
Q326L |
probably damaging |
Het |
| Itgb3 |
T |
A |
11: 104,556,346 (GRCm39) |
I729N |
probably damaging |
Het |
| Kcnab2 |
A |
G |
4: 152,486,403 (GRCm39) |
S132P |
probably damaging |
Het |
| Lama3 |
C |
T |
18: 12,672,850 (GRCm39) |
A2481V |
probably damaging |
Het |
| Lama3 |
T |
C |
18: 12,631,735 (GRCm39) |
|
probably benign |
Het |
| Lce1e |
A |
T |
3: 92,615,178 (GRCm39) |
C56* |
probably null |
Het |
| Lmcd1 |
T |
C |
6: 112,264,832 (GRCm39) |
|
probably benign |
Het |
| Lrrc14 |
T |
A |
15: 76,597,562 (GRCm39) |
|
probably null |
Het |
| Lypd8l |
A |
T |
11: 58,503,338 (GRCm39) |
|
probably null |
Het |
| Map4k5 |
G |
A |
12: 69,865,212 (GRCm39) |
P591L |
probably benign |
Het |
| Mapk13 |
C |
A |
17: 28,995,284 (GRCm39) |
D168E |
probably damaging |
Het |
| Marf1 |
A |
C |
16: 13,950,529 (GRCm39) |
H952Q |
possibly damaging |
Het |
| Megf6 |
T |
C |
4: 154,338,738 (GRCm39) |
|
probably null |
Het |
| Mical3 |
T |
C |
6: 121,010,748 (GRCm39) |
I411M |
probably damaging |
Het |
| Myo5a |
A |
T |
9: 75,124,789 (GRCm39) |
K1781N |
probably damaging |
Het |
| N4bp2 |
T |
C |
5: 65,965,473 (GRCm39) |
V1174A |
probably benign |
Het |
| Ncdn |
A |
T |
4: 126,644,216 (GRCm39) |
L202Q |
probably damaging |
Het |
| Ncor1 |
T |
A |
11: 62,283,464 (GRCm39) |
M408L |
possibly damaging |
Het |
| Nf1 |
T |
C |
11: 79,300,235 (GRCm39) |
L249P |
probably damaging |
Het |
| Nlrp9b |
T |
A |
7: 19,783,521 (GRCm39) |
|
probably null |
Het |
| Nxpe3 |
A |
T |
16: 55,669,996 (GRCm39) |
Y370N |
probably damaging |
Het |
| P2rx2 |
T |
A |
5: 110,489,434 (GRCm39) |
T167S |
probably benign |
Het |
| Pcdhb19 |
G |
T |
18: 37,632,161 (GRCm39) |
R652L |
probably benign |
Het |
| Pcdhga12 |
T |
C |
18: 37,901,334 (GRCm39) |
L722P |
probably benign |
Het |
| Pde6a |
A |
T |
18: 61,378,663 (GRCm39) |
I329F |
probably damaging |
Het |
| Pdpr |
T |
A |
8: 111,828,583 (GRCm39) |
S29T |
probably benign |
Het |
| Pfkfb3 |
T |
C |
2: 11,491,123 (GRCm39) |
D173G |
probably benign |
Het |
| Plcd4 |
A |
G |
1: 74,604,961 (GRCm39) |
|
probably null |
Het |
| Polr1g |
T |
A |
7: 19,091,684 (GRCm39) |
Q141L |
probably damaging |
Het |
| Pou2f2 |
A |
G |
7: 24,796,533 (GRCm39) |
|
probably benign |
Het |
| Ppp1r14c |
TGGCGGCGGCGGCGGCGG |
TGGCGGCGGCGGCGG |
10: 3,316,702 (GRCm39) |
|
probably benign |
Het |
| Ppp1r42 |
T |
C |
1: 10,073,611 (GRCm39) |
|
probably benign |
Het |
| Ptpre |
C |
T |
7: 135,270,861 (GRCm39) |
H346Y |
probably benign |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Rab12 |
A |
T |
17: 66,805,103 (GRCm39) |
Y142N |
probably damaging |
Het |
| Rai14 |
A |
C |
15: 10,572,556 (GRCm39) |
M857R |
probably damaging |
Het |
| Ranbp2 |
A |
G |
10: 58,328,243 (GRCm39) |
K2753R |
probably damaging |
Het |
| Rasa4 |
A |
T |
5: 136,132,765 (GRCm39) |
K6* |
probably null |
Het |
| Rasgef1a |
A |
G |
6: 118,066,100 (GRCm39) |
M438V |
probably benign |
Het |
| Recql |
T |
G |
6: 142,304,732 (GRCm39) |
|
probably benign |
Het |
| Rftn2 |
A |
G |
1: 55,211,198 (GRCm39) |
V425A |
probably benign |
Het |
| Ror1 |
A |
G |
4: 100,267,001 (GRCm39) |
Y234C |
probably damaging |
Het |
| Sap30l |
T |
A |
11: 57,696,880 (GRCm39) |
L70Q |
probably damaging |
Het |
| Scn4a |
T |
C |
11: 106,210,828 (GRCm39) |
R1730G |
probably damaging |
Het |
| Serinc5 |
T |
G |
13: 92,827,488 (GRCm39) |
I268R |
probably damaging |
Het |
| Sin3b |
G |
A |
8: 73,471,576 (GRCm39) |
V432I |
possibly damaging |
Het |
| Slc30a6 |
T |
C |
17: 74,719,649 (GRCm39) |
M203T |
possibly damaging |
Het |
| Soat1 |
T |
C |
1: 156,259,898 (GRCm39) |
N481S |
probably damaging |
Het |
| Sos2 |
G |
A |
12: 69,686,928 (GRCm39) |
T206I |
probably benign |
Het |
| Sp100 |
G |
T |
1: 85,632,724 (GRCm39) |
A132S |
probably benign |
Het |
| Sp140l1 |
C |
T |
1: 85,066,521 (GRCm39) |
|
probably benign |
Het |
| Spata31d1c |
T |
A |
13: 65,183,604 (GRCm39) |
L382* |
probably null |
Het |
| Stard9 |
T |
A |
2: 120,531,341 (GRCm39) |
W2533R |
probably benign |
Het |
| Tas2r126 |
A |
G |
6: 42,412,324 (GRCm39) |
T286A |
probably benign |
Het |
| Tedc2 |
T |
A |
17: 24,436,910 (GRCm39) |
K275M |
probably damaging |
Het |
| Ten1 |
A |
T |
11: 116,109,057 (GRCm39) |
K242N |
probably benign |
Het |
| Thoc2l |
A |
T |
5: 104,665,616 (GRCm39) |
D46V |
possibly damaging |
Het |
| Tial1 |
C |
T |
7: 128,056,752 (GRCm39) |
V1I |
probably damaging |
Het |
| Tle2 |
G |
A |
10: 81,424,725 (GRCm39) |
R649H |
possibly damaging |
Het |
| Tmem178 |
A |
G |
17: 81,252,374 (GRCm39) |
D86G |
probably benign |
Het |
| Trim29 |
T |
A |
9: 43,240,872 (GRCm39) |
D528E |
possibly damaging |
Het |
| Vmn2r61 |
A |
T |
7: 41,950,132 (GRCm39) |
T851S |
probably benign |
Het |
| Vmn2r72 |
T |
A |
7: 85,399,806 (GRCm39) |
Q414H |
possibly damaging |
Het |
| Yars1 |
A |
T |
4: 129,083,675 (GRCm39) |
|
probably benign |
Het |
| Yipf4 |
A |
G |
17: 74,801,087 (GRCm39) |
Q135R |
probably damaging |
Het |
| Zfp341 |
G |
A |
2: 154,487,786 (GRCm39) |
|
probably benign |
Het |
| Zfp426 |
T |
C |
9: 20,381,334 (GRCm39) |
Y536C |
probably damaging |
Het |
| Zp2 |
T |
G |
7: 119,734,995 (GRCm39) |
Y430S |
probably damaging |
Het |
|
| Other mutations in Dhx57 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00642:Dhx57
|
APN |
17 |
80,582,405 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00811:Dhx57
|
APN |
17 |
80,560,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01389:Dhx57
|
APN |
17 |
80,588,652 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL01468:Dhx57
|
APN |
17 |
80,563,039 (GRCm39) |
nonsense |
probably null |
|
|
IGL01908:Dhx57
|
APN |
17 |
80,558,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01965:Dhx57
|
APN |
17 |
80,576,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02147:Dhx57
|
APN |
17 |
80,567,752 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02275:Dhx57
|
APN |
17 |
80,582,268 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02349:Dhx57
|
APN |
17 |
80,563,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02405:Dhx57
|
APN |
17 |
80,562,979 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02588:Dhx57
|
APN |
17 |
80,576,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02673:Dhx57
|
APN |
17 |
80,574,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02836:Dhx57
|
APN |
17 |
80,574,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02889:Dhx57
|
APN |
17 |
80,554,581 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL03085:Dhx57
|
APN |
17 |
80,565,526 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
P0014:Dhx57
|
UTSW |
17 |
80,582,620 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4377001:Dhx57
|
UTSW |
17 |
80,571,404 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0100:Dhx57
|
UTSW |
17 |
80,582,585 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0100:Dhx57
|
UTSW |
17 |
80,582,585 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0129:Dhx57
|
UTSW |
17 |
80,546,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0200:Dhx57
|
UTSW |
17 |
80,558,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0309:Dhx57
|
UTSW |
17 |
80,582,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0375:Dhx57
|
UTSW |
17 |
80,565,550 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0396:Dhx57
|
UTSW |
17 |
80,582,226 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0520:Dhx57
|
UTSW |
17 |
80,565,604 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0554:Dhx57
|
UTSW |
17 |
80,567,665 (GRCm39) |
nonsense |
probably null |
|
|
R0661:Dhx57
|
UTSW |
17 |
80,576,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0883:Dhx57
|
UTSW |
17 |
80,577,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0900:Dhx57
|
UTSW |
17 |
80,583,011 (GRCm39) |
missense |
probably benign |
|
|
R0963:Dhx57
|
UTSW |
17 |
80,582,956 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1469:Dhx57
|
UTSW |
17 |
80,561,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Dhx57
|
UTSW |
17 |
80,561,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1660:Dhx57
|
UTSW |
17 |
80,553,157 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1707:Dhx57
|
UTSW |
17 |
80,582,655 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1822:Dhx57
|
UTSW |
17 |
80,560,514 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1853:Dhx57
|
UTSW |
17 |
80,582,308 (GRCm39) |
nonsense |
probably null |
|
|
R1942:Dhx57
|
UTSW |
17 |
80,572,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2043:Dhx57
|
UTSW |
17 |
80,560,509 (GRCm39) |
splice site |
probably benign |
|
|
R2106:Dhx57
|
UTSW |
17 |
80,582,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2127:Dhx57
|
UTSW |
17 |
80,580,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2183:Dhx57
|
UTSW |
17 |
80,582,760 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2249:Dhx57
|
UTSW |
17 |
80,588,663 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2400:Dhx57
|
UTSW |
17 |
80,567,845 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2404:Dhx57
|
UTSW |
17 |
80,561,733 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2513:Dhx57
|
UTSW |
17 |
80,549,378 (GRCm39) |
splice site |
probably null |
|
|
R2869:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2869:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2870:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2870:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2871:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2871:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2874:Dhx57
|
UTSW |
17 |
80,558,805 (GRCm39) |
missense |
probably benign |
0.22 |
|
R3819:Dhx57
|
UTSW |
17 |
80,572,503 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3964:Dhx57
|
UTSW |
17 |
80,572,541 (GRCm39) |
nonsense |
probably null |
|
|
R4535:Dhx57
|
UTSW |
17 |
80,582,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4666:Dhx57
|
UTSW |
17 |
80,582,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4788:Dhx57
|
UTSW |
17 |
80,582,760 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4822:Dhx57
|
UTSW |
17 |
80,549,596 (GRCm39) |
splice site |
probably null |
|
|
R4988:Dhx57
|
UTSW |
17 |
80,558,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5391:Dhx57
|
UTSW |
17 |
80,582,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5559:Dhx57
|
UTSW |
17 |
80,561,808 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5644:Dhx57
|
UTSW |
17 |
80,546,302 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5997:Dhx57
|
UTSW |
17 |
80,553,235 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6090:Dhx57
|
UTSW |
17 |
80,571,375 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6177:Dhx57
|
UTSW |
17 |
80,580,395 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6283:Dhx57
|
UTSW |
17 |
80,582,234 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6802:Dhx57
|
UTSW |
17 |
80,582,750 (GRCm39) |
missense |
probably benign |
0.43 |
|
R6924:Dhx57
|
UTSW |
17 |
80,546,244 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7151:Dhx57
|
UTSW |
17 |
80,580,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7386:Dhx57
|
UTSW |
17 |
80,575,006 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7393:Dhx57
|
UTSW |
17 |
80,563,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7451:Dhx57
|
UTSW |
17 |
80,554,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7602:Dhx57
|
UTSW |
17 |
80,582,290 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7733:Dhx57
|
UTSW |
17 |
80,572,503 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7748:Dhx57
|
UTSW |
17 |
80,572,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7749:Dhx57
|
UTSW |
17 |
80,546,287 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7772:Dhx57
|
UTSW |
17 |
80,580,507 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8213:Dhx57
|
UTSW |
17 |
80,582,585 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8370:Dhx57
|
UTSW |
17 |
80,553,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8371:Dhx57
|
UTSW |
17 |
80,582,919 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8403:Dhx57
|
UTSW |
17 |
80,585,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8467:Dhx57
|
UTSW |
17 |
80,561,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8690:Dhx57
|
UTSW |
17 |
80,577,794 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R9210:Dhx57
|
UTSW |
17 |
80,576,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9212:Dhx57
|
UTSW |
17 |
80,576,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9447:Dhx57
|
UTSW |
17 |
80,549,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9562:Dhx57
|
UTSW |
17 |
80,561,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9669:Dhx57
|
UTSW |
17 |
80,553,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9717:Dhx57
|
UTSW |
17 |
80,582,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dhx57
|
UTSW |
17 |
80,558,777 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dhx57
|
UTSW |
17 |
80,553,234 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCTGGCAAGTCAAGTTACTTTC -3'
(R):5'- TTTCCAGATACGACGCAGGC -3'
Sequencing Primer
(F):5'- AATGTCTTCTTGAGGATGTGAAAGTC -3'
(R):5'- TACGACGCAGGCAAAGG -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation