Incidental Mutation 'R4869:Cfap65'
| ID |
376377 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cfap65
|
| Ensembl Gene |
ENSMUSG00000047021 |
| Gene Name |
cilia and flagella associated protein 65 |
| Synonyms |
Ccdc108, B230363K08Rik |
| MMRRC Submission |
042479-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.720)
|
| Stock # |
R4869 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
74941230-74974758 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 74958420 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 896
(S896P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000092440
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094844]
|
| AlphaFold |
Q3V0B4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094844
AA Change: S896P
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000092440
Gene: ENSMUSG00000047021
AA Change: S896P
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
111 |
133 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
745 |
890 |
9.31e-5 |
PROSPERO |
|
internal_repeat_1
|
1167 |
1322 |
9.31e-5 |
PROSPERO |
|
low complexity region
|
1350 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1574 |
1592 |
N/A |
INTRINSIC |
|
coiled coil region
|
1687 |
1724 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000130489
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139950
|
| Meta Mutation Damage Score |
0.0751 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.3%
|
| Validation Efficiency |
99% (102/103) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene has putative coiled-coil domains and may be a transmembrane protein. The chicken ortholog of this gene is involved in the Rose-comb mutation, which is a large chromosome inversion, resulting in altered comb morphology and defects in sperm motility. [provided by RefSeq, Aug 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017B05Rik |
C |
A |
9: 57,161,488 (GRCm39) |
K943N |
probably damaging |
Het |
| Abca13 |
G |
A |
11: 9,265,434 (GRCm39) |
|
probably null |
Het |
| Ankub1 |
A |
G |
3: 57,597,751 (GRCm39) |
L73P |
probably damaging |
Het |
| Birc6 |
A |
G |
17: 74,893,007 (GRCm39) |
I982V |
probably benign |
Het |
| Cabyr |
G |
T |
18: 12,884,875 (GRCm39) |
*454L |
probably null |
Het |
| Ccdc57 |
C |
T |
11: 120,794,344 (GRCm39) |
|
probably null |
Het |
| Cd209c |
A |
G |
8: 3,994,077 (GRCm39) |
F128L |
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,212,713 (GRCm39) |
I1566N |
probably damaging |
Het |
| Cdon |
T |
C |
9: 35,364,200 (GRCm39) |
V106A |
possibly damaging |
Het |
| Cebpa |
G |
T |
7: 34,819,246 (GRCm39) |
G135C |
probably damaging |
Het |
| Ciz1 |
T |
C |
2: 32,254,247 (GRCm39) |
S63P |
probably damaging |
Het |
| Clybl |
G |
A |
14: 122,621,618 (GRCm39) |
V269M |
probably damaging |
Het |
| Ctnnb1 |
G |
T |
9: 120,782,060 (GRCm39) |
V358L |
possibly damaging |
Het |
| Cwh43 |
G |
T |
5: 73,586,016 (GRCm39) |
|
probably null |
Het |
| Cyp2d10 |
G |
A |
15: 82,287,967 (GRCm39) |
R379C |
probably benign |
Het |
| Dab2ip |
C |
A |
2: 35,610,049 (GRCm39) |
R727S |
probably damaging |
Het |
| Dmrt1 |
T |
A |
19: 25,483,219 (GRCm39) |
M1K |
probably null |
Het |
| Dock1 |
A |
T |
7: 134,335,800 (GRCm39) |
I65F |
probably damaging |
Het |
| Ercc2 |
T |
C |
7: 19,120,732 (GRCm39) |
V155A |
probably damaging |
Het |
| Exph5 |
A |
C |
9: 53,287,539 (GRCm39) |
D1540A |
possibly damaging |
Het |
| Fat3 |
T |
A |
9: 16,288,773 (GRCm39) |
H250L |
probably damaging |
Het |
| Fbxw10 |
C |
A |
11: 62,753,557 (GRCm39) |
A517E |
probably damaging |
Het |
| Furin |
A |
T |
7: 80,046,727 (GRCm39) |
N176K |
probably damaging |
Het |
| Gabrb3 |
A |
G |
7: 57,442,207 (GRCm39) |
|
probably benign |
Het |
| Gabrg2 |
A |
T |
11: 41,811,231 (GRCm39) |
S305T |
probably damaging |
Het |
| Gas6 |
G |
T |
8: 13,525,086 (GRCm39) |
S299R |
possibly damaging |
Het |
| Gga3 |
G |
T |
11: 115,477,111 (GRCm39) |
|
probably benign |
Het |
| Gle1 |
A |
G |
2: 29,826,032 (GRCm39) |
E37G |
possibly damaging |
Het |
| Gm7964 |
A |
G |
7: 83,405,350 (GRCm39) |
D80G |
possibly damaging |
Het |
| Gne |
C |
T |
4: 44,055,204 (GRCm39) |
|
probably null |
Het |
| Grid2 |
G |
T |
6: 64,406,724 (GRCm39) |
G695W |
probably damaging |
Het |
| H2-M10.6 |
A |
T |
17: 37,123,425 (GRCm39) |
M40L |
probably benign |
Het |
| Hectd4 |
G |
T |
5: 121,460,735 (GRCm39) |
V905L |
possibly damaging |
Het |
| Isyna1 |
C |
A |
8: 71,049,412 (GRCm39) |
S441R |
possibly damaging |
Het |
| Kcnh3 |
C |
T |
15: 99,139,913 (GRCm39) |
S933L |
probably benign |
Het |
| Knl1 |
T |
C |
2: 118,902,832 (GRCm39) |
I1511T |
possibly damaging |
Het |
| Krt73 |
T |
C |
15: 101,704,833 (GRCm39) |
E351G |
probably damaging |
Het |
| Lipo4 |
C |
T |
19: 33,478,953 (GRCm39) |
|
probably null |
Het |
| Llgl1 |
T |
A |
11: 60,598,036 (GRCm39) |
L360* |
probably null |
Het |
| Map2k5 |
G |
A |
9: 63,229,525 (GRCm39) |
R169* |
probably null |
Het |
| Muc19 |
A |
T |
15: 91,781,910 (GRCm39) |
|
noncoding transcript |
Het |
| Muc4 |
G |
A |
16: 32,754,836 (GRCm38) |
|
probably benign |
Het |
| Myh4 |
A |
G |
11: 67,143,490 (GRCm39) |
E1074G |
probably damaging |
Het |
| Naip5 |
C |
T |
13: 100,381,639 (GRCm39) |
G210E |
probably damaging |
Het |
| Nalcn |
A |
G |
14: 123,837,296 (GRCm39) |
S23P |
probably benign |
Het |
| Nepro |
T |
A |
16: 44,550,536 (GRCm39) |
M176K |
probably damaging |
Het |
| Nlrp6 |
G |
A |
7: 140,504,006 (GRCm39) |
C704Y |
probably damaging |
Het |
| Notch1 |
A |
G |
2: 26,361,191 (GRCm39) |
S1100P |
probably benign |
Het |
| Nrxn3 |
A |
G |
12: 88,762,352 (GRCm39) |
E133G |
possibly damaging |
Het |
| Obi1 |
A |
G |
14: 104,716,252 (GRCm39) |
I707T |
probably damaging |
Het |
| Parp9 |
T |
C |
16: 35,777,274 (GRCm39) |
L406S |
probably damaging |
Het |
| Peak1 |
G |
T |
9: 56,134,876 (GRCm39) |
A155D |
probably benign |
Het |
| Piezo1 |
G |
A |
8: 123,214,284 (GRCm39) |
H1628Y |
probably benign |
Het |
| Piwil2 |
A |
G |
14: 70,632,811 (GRCm39) |
V587A |
probably benign |
Het |
| Pkn2 |
A |
G |
3: 142,509,379 (GRCm39) |
Y722H |
probably damaging |
Het |
| Plch2 |
A |
T |
4: 155,073,885 (GRCm39) |
I834K |
probably benign |
Het |
| Pld1 |
A |
G |
3: 28,163,951 (GRCm39) |
T795A |
possibly damaging |
Het |
| Plekhh1 |
A |
G |
12: 79,097,160 (GRCm39) |
S103G |
probably benign |
Het |
| Ppl |
T |
C |
16: 4,922,753 (GRCm39) |
Y246C |
probably damaging |
Het |
| Prpf40b |
G |
A |
15: 99,207,726 (GRCm39) |
|
probably benign |
Het |
| Prr14l |
A |
G |
5: 32,986,177 (GRCm39) |
L1106P |
probably damaging |
Het |
| Ptbp3 |
T |
A |
4: 59,524,443 (GRCm39) |
I28F |
possibly damaging |
Het |
| Ptrh2 |
A |
T |
11: 86,580,631 (GRCm39) |
K83* |
probably null |
Het |
| Rai1 |
T |
C |
11: 60,077,588 (GRCm39) |
S551P |
probably damaging |
Het |
| Rapgefl1 |
A |
T |
11: 98,741,935 (GRCm39) |
Q633L |
probably damaging |
Het |
| Rb1cc1 |
T |
C |
1: 6,285,245 (GRCm39) |
|
probably benign |
Het |
| Rif1 |
T |
A |
2: 51,983,623 (GRCm39) |
|
probably benign |
Het |
| Rnf141 |
A |
G |
7: 110,424,557 (GRCm39) |
Y101H |
probably damaging |
Het |
| Rttn |
T |
A |
18: 89,061,138 (GRCm39) |
L1102* |
probably null |
Het |
| Sall4 |
G |
A |
2: 168,597,637 (GRCm39) |
S401F |
probably damaging |
Het |
| Saxo5 |
G |
A |
8: 3,537,148 (GRCm39) |
S498N |
probably damaging |
Het |
| Sec11c |
T |
C |
18: 65,934,541 (GRCm39) |
I36T |
probably benign |
Het |
| Sel1l |
A |
G |
12: 91,780,828 (GRCm39) |
|
probably benign |
Het |
| Setd1a |
T |
C |
7: 127,396,776 (GRCm39) |
|
probably benign |
Het |
| Sez6l2 |
C |
T |
7: 126,561,014 (GRCm39) |
P433L |
probably benign |
Het |
| Sgf29 |
T |
C |
7: 126,248,547 (GRCm39) |
|
probably benign |
Het |
| Slc47a1 |
A |
G |
11: 61,253,520 (GRCm39) |
V305A |
probably benign |
Het |
| Slco1a8 |
T |
C |
6: 141,933,492 (GRCm39) |
D431G |
probably damaging |
Het |
| Sun2 |
T |
C |
15: 79,612,587 (GRCm39) |
|
probably benign |
Het |
| Tecta |
T |
C |
9: 42,286,830 (GRCm39) |
S609G |
probably benign |
Het |
| Tmprss6 |
T |
A |
15: 78,327,880 (GRCm39) |
|
probably null |
Het |
| Tns1 |
T |
C |
1: 73,991,774 (GRCm39) |
H968R |
probably benign |
Het |
| Tomm34 |
G |
A |
2: 163,896,637 (GRCm39) |
A270V |
probably damaging |
Het |
| Tpo |
T |
C |
12: 30,153,364 (GRCm39) |
K330R |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,542,837 (GRCm39) |
Y33383F |
probably damaging |
Het |
| Unc13c |
G |
T |
9: 73,587,716 (GRCm39) |
A1439D |
probably benign |
Het |
| Vcp |
C |
T |
4: 42,993,691 (GRCm39) |
R147H |
probably benign |
Het |
| Vps13d |
A |
G |
4: 144,854,612 (GRCm39) |
L2272P |
probably damaging |
Het |
| Wdfy3 |
A |
G |
5: 102,042,787 (GRCm39) |
L1988P |
probably damaging |
Het |
| Wwc2 |
A |
G |
8: 48,373,713 (GRCm39) |
F51S |
probably damaging |
Het |
| Zfp454 |
C |
T |
11: 50,763,980 (GRCm39) |
C373Y |
probably damaging |
Het |
| Zfp853 |
A |
T |
5: 143,274,048 (GRCm39) |
V473E |
probably damaging |
Het |
| Zfp959 |
A |
T |
17: 56,204,228 (GRCm39) |
R85S |
possibly damaging |
Het |
|
| Other mutations in Cfap65 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01107:Cfap65
|
APN |
1 |
74,958,342 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01526:Cfap65
|
APN |
1 |
74,950,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01716:Cfap65
|
APN |
1 |
74,966,353 (GRCm39) |
missense |
probably benign |
|
|
IGL01780:Cfap65
|
APN |
1 |
74,967,507 (GRCm39) |
nonsense |
probably null |
|
|
IGL01993:Cfap65
|
APN |
1 |
74,959,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02164:Cfap65
|
APN |
1 |
74,967,304 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02350:Cfap65
|
APN |
1 |
74,967,507 (GRCm39) |
nonsense |
probably null |
|
|
IGL02357:Cfap65
|
APN |
1 |
74,967,507 (GRCm39) |
nonsense |
probably null |
|
|
IGL02576:Cfap65
|
APN |
1 |
74,942,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02756:Cfap65
|
APN |
1 |
74,944,239 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02792:Cfap65
|
APN |
1 |
74,966,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02874:Cfap65
|
APN |
1 |
74,950,267 (GRCm39) |
nonsense |
probably null |
|
|
IGL03101:Cfap65
|
APN |
1 |
74,967,592 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL03348:Cfap65
|
APN |
1 |
74,966,778 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03396:Cfap65
|
APN |
1 |
74,943,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4131001:Cfap65
|
UTSW |
1 |
74,967,501 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0077:Cfap65
|
UTSW |
1 |
74,971,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0227:Cfap65
|
UTSW |
1 |
74,971,117 (GRCm39) |
nonsense |
probably null |
|
|
R0281:Cfap65
|
UTSW |
1 |
74,966,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0312:Cfap65
|
UTSW |
1 |
74,943,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,968,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,968,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0347:Cfap65
|
UTSW |
1 |
74,965,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0359:Cfap65
|
UTSW |
1 |
74,959,760 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0361:Cfap65
|
UTSW |
1 |
74,964,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Cfap65
|
UTSW |
1 |
74,956,043 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0549:Cfap65
|
UTSW |
1 |
74,957,603 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0646:Cfap65
|
UTSW |
1 |
74,941,328 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0734:Cfap65
|
UTSW |
1 |
74,958,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0763:Cfap65
|
UTSW |
1 |
74,943,841 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0990:Cfap65
|
UTSW |
1 |
74,960,678 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R1079:Cfap65
|
UTSW |
1 |
74,944,872 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1079:Cfap65
|
UTSW |
1 |
74,941,606 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1083:Cfap65
|
UTSW |
1 |
74,957,663 (GRCm39) |
splice site |
probably benign |
|
|
R1159:Cfap65
|
UTSW |
1 |
74,968,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1282:Cfap65
|
UTSW |
1 |
74,964,263 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1644:Cfap65
|
UTSW |
1 |
74,956,334 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1796:Cfap65
|
UTSW |
1 |
74,958,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1950:Cfap65
|
UTSW |
1 |
74,946,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2079:Cfap65
|
UTSW |
1 |
74,956,358 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2132:Cfap65
|
UTSW |
1 |
74,946,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2136:Cfap65
|
UTSW |
1 |
74,956,432 (GRCm39) |
frame shift |
probably null |
|
|
R2219:Cfap65
|
UTSW |
1 |
74,943,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2220:Cfap65
|
UTSW |
1 |
74,943,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2291:Cfap65
|
UTSW |
1 |
74,965,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2417:Cfap65
|
UTSW |
1 |
74,966,345 (GRCm39) |
small insertion |
probably benign |
|
|
R3114:Cfap65
|
UTSW |
1 |
74,966,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4202:Cfap65
|
UTSW |
1 |
74,959,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4214:Cfap65
|
UTSW |
1 |
74,966,840 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4254:Cfap65
|
UTSW |
1 |
74,942,517 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4547:Cfap65
|
UTSW |
1 |
74,946,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4548:Cfap65
|
UTSW |
1 |
74,946,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4588:Cfap65
|
UTSW |
1 |
74,943,215 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4657:Cfap65
|
UTSW |
1 |
74,964,513 (GRCm39) |
intron |
probably benign |
|
|
R4701:Cfap65
|
UTSW |
1 |
74,958,067 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4755:Cfap65
|
UTSW |
1 |
74,967,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4820:Cfap65
|
UTSW |
1 |
74,966,791 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4831:Cfap65
|
UTSW |
1 |
74,956,454 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4866:Cfap65
|
UTSW |
1 |
74,964,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4881:Cfap65
|
UTSW |
1 |
74,946,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4884:Cfap65
|
UTSW |
1 |
74,942,283 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R4950:Cfap65
|
UTSW |
1 |
74,945,495 (GRCm39) |
nonsense |
probably null |
|
|
R5074:Cfap65
|
UTSW |
1 |
74,962,137 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5083:Cfap65
|
UTSW |
1 |
74,945,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5164:Cfap65
|
UTSW |
1 |
74,965,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5268:Cfap65
|
UTSW |
1 |
74,964,061 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5333:Cfap65
|
UTSW |
1 |
74,942,334 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5417:Cfap65
|
UTSW |
1 |
74,964,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5582:Cfap65
|
UTSW |
1 |
74,946,677 (GRCm39) |
intron |
probably benign |
|
|
R5669:Cfap65
|
UTSW |
1 |
74,964,127 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6010:Cfap65
|
UTSW |
1 |
74,962,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6084:Cfap65
|
UTSW |
1 |
74,959,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6112:Cfap65
|
UTSW |
1 |
74,942,298 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6425:Cfap65
|
UTSW |
1 |
74,966,868 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6677:Cfap65
|
UTSW |
1 |
74,943,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6693:Cfap65
|
UTSW |
1 |
74,956,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6838:Cfap65
|
UTSW |
1 |
74,971,180 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6861:Cfap65
|
UTSW |
1 |
74,964,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6958:Cfap65
|
UTSW |
1 |
74,971,058 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R7134:Cfap65
|
UTSW |
1 |
74,965,792 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7320:Cfap65
|
UTSW |
1 |
74,965,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7340:Cfap65
|
UTSW |
1 |
74,960,742 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7426:Cfap65
|
UTSW |
1 |
74,959,585 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7529:Cfap65
|
UTSW |
1 |
74,965,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7634:Cfap65
|
UTSW |
1 |
74,941,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7654:Cfap65
|
UTSW |
1 |
74,972,303 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7704:Cfap65
|
UTSW |
1 |
74,967,527 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7727:Cfap65
|
UTSW |
1 |
74,965,784 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7895:Cfap65
|
UTSW |
1 |
74,972,321 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8215:Cfap65
|
UTSW |
1 |
74,949,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8344:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8345:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8413:Cfap65
|
UTSW |
1 |
74,956,328 (GRCm39) |
nonsense |
probably null |
|
|
R8431:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8432:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8528:Cfap65
|
UTSW |
1 |
74,945,096 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8809:Cfap65
|
UTSW |
1 |
74,942,382 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8996:Cfap65
|
UTSW |
1 |
74,941,347 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9020:Cfap65
|
UTSW |
1 |
74,959,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9043:Cfap65
|
UTSW |
1 |
74,943,847 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9127:Cfap65
|
UTSW |
1 |
74,958,510 (GRCm39) |
splice site |
probably benign |
|
|
R9187:Cfap65
|
UTSW |
1 |
74,956,517 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9210:Cfap65
|
UTSW |
1 |
74,959,567 (GRCm39) |
missense |
probably benign |
|
|
R9212:Cfap65
|
UTSW |
1 |
74,959,567 (GRCm39) |
missense |
probably benign |
|
|
R9273:Cfap65
|
UTSW |
1 |
74,960,769 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9454:Cfap65
|
UTSW |
1 |
74,944,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9514:Cfap65
|
UTSW |
1 |
74,945,468 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9595:Cfap65
|
UTSW |
1 |
74,946,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9721:Cfap65
|
UTSW |
1 |
74,958,501 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9742:Cfap65
|
UTSW |
1 |
74,943,840 (GRCm39) |
missense |
probably benign |
0.08 |
|
RF009:Cfap65
|
UTSW |
1 |
74,944,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Cfap65
|
UTSW |
1 |
74,949,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACAGCCAACTAGCTTCTGGG -3'
(R):5'- GCAAGCATTTGTAACAGGACC -3'
Sequencing Primer
(F):5'- GTGCAAGGATCCGTATCTTGTCC -3'
(R):5'- GCATTTGTAACAGGACCTCCCC -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation