Incidental Mutation 'R4869:Pld1'
| ID |
376389 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pld1
|
| Ensembl Gene |
ENSMUSG00000027695 |
| Gene Name |
phospholipase D1 |
| Synonyms |
Pld1a, Pld1b |
| MMRRC Submission |
042479-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4869 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
27992844-28187511 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 28163951 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 795
(T795A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113810
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000067757]
[ENSMUST00000120834]
[ENSMUST00000123539]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000067757
AA Change: T795A
PolyPhen 2
Score 0.842 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000064694
Gene: ENSMUSG00000027695
AA Change: T795A
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
79 |
209 |
7.97e-25 |
SMART |
|
PH
|
220 |
330 |
5.71e-9 |
SMART |
|
PLDc
|
459 |
486 |
6.6e-6 |
SMART |
|
low complexity region
|
503 |
517 |
N/A |
INTRINSIC |
|
low complexity region
|
575 |
589 |
N/A |
INTRINSIC |
|
PLDc
|
853 |
880 |
1.34e-6 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000120834
AA Change: T795A
PolyPhen 2
Score 0.842 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000113810
Gene: ENSMUSG00000027695
AA Change: T795A
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
79 |
209 |
7.97e-25 |
SMART |
|
PH
|
220 |
330 |
5.71e-9 |
SMART |
|
PLDc
|
459 |
486 |
6.6e-6 |
SMART |
|
low complexity region
|
503 |
517 |
N/A |
INTRINSIC |
|
low complexity region
|
575 |
589 |
N/A |
INTRINSIC |
|
PLDc
|
853 |
880 |
1.34e-6 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000123539
AA Change: T833A
|
| SMART Domains |
Protein: ENSMUSP00000118727
Gene: ENSMUSG00000027695
AA Change: T833A
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
79 |
209 |
7.97e-25 |
SMART |
|
PH
|
220 |
330 |
5.71e-9 |
SMART |
|
PLDc
|
459 |
486 |
6.6e-6 |
SMART |
|
low complexity region
|
503 |
517 |
N/A |
INTRINSIC |
|
low complexity region
|
575 |
586 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000126594
AA Change: T15A
|
| SMART Domains |
Protein: ENSMUSP00000121569
Gene: ENSMUSG00000027695
AA Change: T15A
| Domain | Start | End | E-Value | Type |
|---|
|
PLDc
|
74 |
101 |
1.34e-6 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000148827
AA Change: T606A
|
| SMART Domains |
Protein: ENSMUSP00000120273
Gene: ENSMUSG00000027695
AA Change: T606A
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
32 |
142 |
5.71e-9 |
SMART |
|
PLDc
|
271 |
298 |
6.6e-6 |
SMART |
|
low complexity region
|
315 |
329 |
N/A |
INTRINSIC |
|
low complexity region
|
387 |
401 |
N/A |
INTRINSIC |
|
PLDc
|
665 |
715 |
2.5e1 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.3%
|
| Validation Efficiency |
99% (102/103) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011]
PHENOTYPE: Homozygotes for a null allele show reduced tumor growth and angiogenesis. Homozygotes for a second null allele show abnormal hepatic autophagy after food restriction. Homozygotes for a third null allele show altered platelet activation and protection from thrombosis and ischemic brain injury. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(3) : Targeted, other(2) Gene trapped(1) |
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017B05Rik |
C |
A |
9: 57,161,488 (GRCm39) |
K943N |
probably damaging |
Het |
| Abca13 |
G |
A |
11: 9,265,434 (GRCm39) |
|
probably null |
Het |
| Ankub1 |
A |
G |
3: 57,597,751 (GRCm39) |
L73P |
probably damaging |
Het |
| Birc6 |
A |
G |
17: 74,893,007 (GRCm39) |
I982V |
probably benign |
Het |
| Cabyr |
G |
T |
18: 12,884,875 (GRCm39) |
*454L |
probably null |
Het |
| Ccdc57 |
C |
T |
11: 120,794,344 (GRCm39) |
|
probably null |
Het |
| Cd209c |
A |
G |
8: 3,994,077 (GRCm39) |
F128L |
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,212,713 (GRCm39) |
I1566N |
probably damaging |
Het |
| Cdon |
T |
C |
9: 35,364,200 (GRCm39) |
V106A |
possibly damaging |
Het |
| Cebpa |
G |
T |
7: 34,819,246 (GRCm39) |
G135C |
probably damaging |
Het |
| Cfap65 |
A |
G |
1: 74,958,420 (GRCm39) |
S896P |
probably benign |
Het |
| Ciz1 |
T |
C |
2: 32,254,247 (GRCm39) |
S63P |
probably damaging |
Het |
| Clybl |
G |
A |
14: 122,621,618 (GRCm39) |
V269M |
probably damaging |
Het |
| Ctnnb1 |
G |
T |
9: 120,782,060 (GRCm39) |
V358L |
possibly damaging |
Het |
| Cwh43 |
G |
T |
5: 73,586,016 (GRCm39) |
|
probably null |
Het |
| Cyp2d10 |
G |
A |
15: 82,287,967 (GRCm39) |
R379C |
probably benign |
Het |
| Dab2ip |
C |
A |
2: 35,610,049 (GRCm39) |
R727S |
probably damaging |
Het |
| Dmrt1 |
T |
A |
19: 25,483,219 (GRCm39) |
M1K |
probably null |
Het |
| Dock1 |
A |
T |
7: 134,335,800 (GRCm39) |
I65F |
probably damaging |
Het |
| Ercc2 |
T |
C |
7: 19,120,732 (GRCm39) |
V155A |
probably damaging |
Het |
| Exph5 |
A |
C |
9: 53,287,539 (GRCm39) |
D1540A |
possibly damaging |
Het |
| Fat3 |
T |
A |
9: 16,288,773 (GRCm39) |
H250L |
probably damaging |
Het |
| Fbxw10 |
C |
A |
11: 62,753,557 (GRCm39) |
A517E |
probably damaging |
Het |
| Furin |
A |
T |
7: 80,046,727 (GRCm39) |
N176K |
probably damaging |
Het |
| Gabrb3 |
A |
G |
7: 57,442,207 (GRCm39) |
|
probably benign |
Het |
| Gabrg2 |
A |
T |
11: 41,811,231 (GRCm39) |
S305T |
probably damaging |
Het |
| Gas6 |
G |
T |
8: 13,525,086 (GRCm39) |
S299R |
possibly damaging |
Het |
| Gga3 |
G |
T |
11: 115,477,111 (GRCm39) |
|
probably benign |
Het |
| Gle1 |
A |
G |
2: 29,826,032 (GRCm39) |
E37G |
possibly damaging |
Het |
| Gm7964 |
A |
G |
7: 83,405,350 (GRCm39) |
D80G |
possibly damaging |
Het |
| Gne |
C |
T |
4: 44,055,204 (GRCm39) |
|
probably null |
Het |
| Grid2 |
G |
T |
6: 64,406,724 (GRCm39) |
G695W |
probably damaging |
Het |
| H2-M10.6 |
A |
T |
17: 37,123,425 (GRCm39) |
M40L |
probably benign |
Het |
| Hectd4 |
G |
T |
5: 121,460,735 (GRCm39) |
V905L |
possibly damaging |
Het |
| Isyna1 |
C |
A |
8: 71,049,412 (GRCm39) |
S441R |
possibly damaging |
Het |
| Kcnh3 |
C |
T |
15: 99,139,913 (GRCm39) |
S933L |
probably benign |
Het |
| Knl1 |
T |
C |
2: 118,902,832 (GRCm39) |
I1511T |
possibly damaging |
Het |
| Krt73 |
T |
C |
15: 101,704,833 (GRCm39) |
E351G |
probably damaging |
Het |
| Lipo4 |
C |
T |
19: 33,478,953 (GRCm39) |
|
probably null |
Het |
| Llgl1 |
T |
A |
11: 60,598,036 (GRCm39) |
L360* |
probably null |
Het |
| Map2k5 |
G |
A |
9: 63,229,525 (GRCm39) |
R169* |
probably null |
Het |
| Muc19 |
A |
T |
15: 91,781,910 (GRCm39) |
|
noncoding transcript |
Het |
| Muc4 |
G |
A |
16: 32,754,836 (GRCm38) |
|
probably benign |
Het |
| Myh4 |
A |
G |
11: 67,143,490 (GRCm39) |
E1074G |
probably damaging |
Het |
| Naip5 |
C |
T |
13: 100,381,639 (GRCm39) |
G210E |
probably damaging |
Het |
| Nalcn |
A |
G |
14: 123,837,296 (GRCm39) |
S23P |
probably benign |
Het |
| Nepro |
T |
A |
16: 44,550,536 (GRCm39) |
M176K |
probably damaging |
Het |
| Nlrp6 |
G |
A |
7: 140,504,006 (GRCm39) |
C704Y |
probably damaging |
Het |
| Notch1 |
A |
G |
2: 26,361,191 (GRCm39) |
S1100P |
probably benign |
Het |
| Nrxn3 |
A |
G |
12: 88,762,352 (GRCm39) |
E133G |
possibly damaging |
Het |
| Obi1 |
A |
G |
14: 104,716,252 (GRCm39) |
I707T |
probably damaging |
Het |
| Parp9 |
T |
C |
16: 35,777,274 (GRCm39) |
L406S |
probably damaging |
Het |
| Peak1 |
G |
T |
9: 56,134,876 (GRCm39) |
A155D |
probably benign |
Het |
| Piezo1 |
G |
A |
8: 123,214,284 (GRCm39) |
H1628Y |
probably benign |
Het |
| Piwil2 |
A |
G |
14: 70,632,811 (GRCm39) |
V587A |
probably benign |
Het |
| Pkn2 |
A |
G |
3: 142,509,379 (GRCm39) |
Y722H |
probably damaging |
Het |
| Plch2 |
A |
T |
4: 155,073,885 (GRCm39) |
I834K |
probably benign |
Het |
| Plekhh1 |
A |
G |
12: 79,097,160 (GRCm39) |
S103G |
probably benign |
Het |
| Ppl |
T |
C |
16: 4,922,753 (GRCm39) |
Y246C |
probably damaging |
Het |
| Prpf40b |
G |
A |
15: 99,207,726 (GRCm39) |
|
probably benign |
Het |
| Prr14l |
A |
G |
5: 32,986,177 (GRCm39) |
L1106P |
probably damaging |
Het |
| Ptbp3 |
T |
A |
4: 59,524,443 (GRCm39) |
I28F |
possibly damaging |
Het |
| Ptrh2 |
A |
T |
11: 86,580,631 (GRCm39) |
K83* |
probably null |
Het |
| Rai1 |
T |
C |
11: 60,077,588 (GRCm39) |
S551P |
probably damaging |
Het |
| Rapgefl1 |
A |
T |
11: 98,741,935 (GRCm39) |
Q633L |
probably damaging |
Het |
| Rb1cc1 |
T |
C |
1: 6,285,245 (GRCm39) |
|
probably benign |
Het |
| Rif1 |
T |
A |
2: 51,983,623 (GRCm39) |
|
probably benign |
Het |
| Rnf141 |
A |
G |
7: 110,424,557 (GRCm39) |
Y101H |
probably damaging |
Het |
| Rttn |
T |
A |
18: 89,061,138 (GRCm39) |
L1102* |
probably null |
Het |
| Sall4 |
G |
A |
2: 168,597,637 (GRCm39) |
S401F |
probably damaging |
Het |
| Saxo5 |
G |
A |
8: 3,537,148 (GRCm39) |
S498N |
probably damaging |
Het |
| Sec11c |
T |
C |
18: 65,934,541 (GRCm39) |
I36T |
probably benign |
Het |
| Sel1l |
A |
G |
12: 91,780,828 (GRCm39) |
|
probably benign |
Het |
| Setd1a |
T |
C |
7: 127,396,776 (GRCm39) |
|
probably benign |
Het |
| Sez6l2 |
C |
T |
7: 126,561,014 (GRCm39) |
P433L |
probably benign |
Het |
| Sgf29 |
T |
C |
7: 126,248,547 (GRCm39) |
|
probably benign |
Het |
| Slc47a1 |
A |
G |
11: 61,253,520 (GRCm39) |
V305A |
probably benign |
Het |
| Slco1a8 |
T |
C |
6: 141,933,492 (GRCm39) |
D431G |
probably damaging |
Het |
| Sun2 |
T |
C |
15: 79,612,587 (GRCm39) |
|
probably benign |
Het |
| Tecta |
T |
C |
9: 42,286,830 (GRCm39) |
S609G |
probably benign |
Het |
| Tmprss6 |
T |
A |
15: 78,327,880 (GRCm39) |
|
probably null |
Het |
| Tns1 |
T |
C |
1: 73,991,774 (GRCm39) |
H968R |
probably benign |
Het |
| Tomm34 |
G |
A |
2: 163,896,637 (GRCm39) |
A270V |
probably damaging |
Het |
| Tpo |
T |
C |
12: 30,153,364 (GRCm39) |
K330R |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,542,837 (GRCm39) |
Y33383F |
probably damaging |
Het |
| Unc13c |
G |
T |
9: 73,587,716 (GRCm39) |
A1439D |
probably benign |
Het |
| Vcp |
C |
T |
4: 42,993,691 (GRCm39) |
R147H |
probably benign |
Het |
| Vps13d |
A |
G |
4: 144,854,612 (GRCm39) |
L2272P |
probably damaging |
Het |
| Wdfy3 |
A |
G |
5: 102,042,787 (GRCm39) |
L1988P |
probably damaging |
Het |
| Wwc2 |
A |
G |
8: 48,373,713 (GRCm39) |
F51S |
probably damaging |
Het |
| Zfp454 |
C |
T |
11: 50,763,980 (GRCm39) |
C373Y |
probably damaging |
Het |
| Zfp853 |
A |
T |
5: 143,274,048 (GRCm39) |
V473E |
probably damaging |
Het |
| Zfp959 |
A |
T |
17: 56,204,228 (GRCm39) |
R85S |
possibly damaging |
Het |
|
| Other mutations in Pld1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Pld1
|
APN |
3 |
28,099,247 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01090:Pld1
|
APN |
3 |
28,142,816 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01140:Pld1
|
APN |
3 |
28,132,386 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01646:Pld1
|
APN |
3 |
28,153,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01830:Pld1
|
APN |
3 |
28,102,153 (GRCm39) |
splice site |
probably benign |
|
|
IGL01946:Pld1
|
APN |
3 |
28,178,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02139:Pld1
|
APN |
3 |
28,174,961 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02189:Pld1
|
APN |
3 |
28,174,932 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02476:Pld1
|
APN |
3 |
28,102,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Pld1
|
APN |
3 |
28,083,309 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02649:Pld1
|
APN |
3 |
28,141,378 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02720:Pld1
|
APN |
3 |
28,141,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02831:Pld1
|
APN |
3 |
28,130,574 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02953:Pld1
|
APN |
3 |
28,166,396 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL03005:Pld1
|
APN |
3 |
28,141,402 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL03251:Pld1
|
APN |
3 |
28,142,814 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03331:Pld1
|
APN |
3 |
28,139,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
A9681:Pld1
|
UTSW |
3 |
28,139,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03134:Pld1
|
UTSW |
3 |
28,083,316 (GRCm39) |
missense |
probably benign |
0.01 |
|
P0023:Pld1
|
UTSW |
3 |
28,102,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0054:Pld1
|
UTSW |
3 |
28,150,033 (GRCm39) |
splice site |
probably benign |
|
|
R0054:Pld1
|
UTSW |
3 |
28,150,033 (GRCm39) |
splice site |
probably benign |
|
|
R0282:Pld1
|
UTSW |
3 |
28,132,422 (GRCm39) |
missense |
probably benign |
|
|
R0372:Pld1
|
UTSW |
3 |
28,142,787 (GRCm39) |
splice site |
probably null |
|
|
R0454:Pld1
|
UTSW |
3 |
28,178,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0492:Pld1
|
UTSW |
3 |
28,163,966 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0505:Pld1
|
UTSW |
3 |
28,174,971 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0667:Pld1
|
UTSW |
3 |
28,133,327 (GRCm39) |
splice site |
probably null |
|
|
R0678:Pld1
|
UTSW |
3 |
28,174,933 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0980:Pld1
|
UTSW |
3 |
28,178,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1200:Pld1
|
UTSW |
3 |
28,103,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1235:Pld1
|
UTSW |
3 |
28,082,883 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1657:Pld1
|
UTSW |
3 |
28,125,336 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1670:Pld1
|
UTSW |
3 |
28,103,389 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1705:Pld1
|
UTSW |
3 |
28,125,426 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1815:Pld1
|
UTSW |
3 |
28,163,917 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2215:Pld1
|
UTSW |
3 |
28,132,542 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3435:Pld1
|
UTSW |
3 |
28,178,772 (GRCm39) |
missense |
probably benign |
0.13 |
|
R3522:Pld1
|
UTSW |
3 |
28,085,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4206:Pld1
|
UTSW |
3 |
28,174,932 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4553:Pld1
|
UTSW |
3 |
28,178,851 (GRCm39) |
missense |
probably benign |
|
|
R4612:Pld1
|
UTSW |
3 |
28,185,882 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4623:Pld1
|
UTSW |
3 |
28,083,393 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4840:Pld1
|
UTSW |
3 |
28,130,700 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4982:Pld1
|
UTSW |
3 |
28,085,447 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5087:Pld1
|
UTSW |
3 |
28,178,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5182:Pld1
|
UTSW |
3 |
28,099,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5384:Pld1
|
UTSW |
3 |
28,079,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6243:Pld1
|
UTSW |
3 |
28,149,954 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6345:Pld1
|
UTSW |
3 |
28,184,896 (GRCm39) |
intron |
probably benign |
|
|
R6692:Pld1
|
UTSW |
3 |
28,095,348 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6881:Pld1
|
UTSW |
3 |
28,132,563 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7197:Pld1
|
UTSW |
3 |
28,078,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7267:Pld1
|
UTSW |
3 |
28,130,550 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7284:Pld1
|
UTSW |
3 |
28,185,882 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7293:Pld1
|
UTSW |
3 |
28,141,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7440:Pld1
|
UTSW |
3 |
28,095,419 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7524:Pld1
|
UTSW |
3 |
28,078,470 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7747:Pld1
|
UTSW |
3 |
28,141,338 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7882:Pld1
|
UTSW |
3 |
28,099,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7936:Pld1
|
UTSW |
3 |
28,130,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8033:Pld1
|
UTSW |
3 |
28,083,359 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8269:Pld1
|
UTSW |
3 |
28,079,388 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8316:Pld1
|
UTSW |
3 |
28,078,361 (GRCm39) |
missense |
probably benign |
|
|
R8427:Pld1
|
UTSW |
3 |
28,142,795 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8523:Pld1
|
UTSW |
3 |
28,140,025 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8832:Pld1
|
UTSW |
3 |
28,177,846 (GRCm39) |
missense |
|
|
|
R8850:Pld1
|
UTSW |
3 |
28,166,439 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9143:Pld1
|
UTSW |
3 |
28,132,643 (GRCm39) |
intron |
probably benign |
|
|
R9549:Pld1
|
UTSW |
3 |
28,125,381 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9648:Pld1
|
UTSW |
3 |
28,174,900 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1088:Pld1
|
UTSW |
3 |
28,083,392 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Pld1
|
UTSW |
3 |
28,185,726 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Pld1
|
UTSW |
3 |
28,130,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCATAGCGCTCAGATCCCATAG -3'
(R):5'- CAGAGCCACCATGGATAACTG -3'
Sequencing Primer
(F):5'- CTCAGATCCCATAGTGATAGCTGG -3'
(R):5'- CCATGGATAACTGCGACATCTG -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation