Mutagenetix > Incidental Mutation

Incidental Mutation 'R4871:Stab2'

376600

Institutional Source

Beutler Lab

Gene Symbol

Stab2

Ensembl Gene

ENSMUSG00000035459

Gene Name

stabilin 2

Synonyms

FEEL-2, STAB-2

MMRRC Submission

042481-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4871 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

86677062-86843889 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 86778099 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 743 (D743G)

Ref Sequence

ENSEMBL: ENSMUSP00000048309 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000035288]

AlphaFold

Q8R4U0

Predicted Effect

probably damaging
Transcript: ENSMUST00000035288
AA Change: D743G

PolyPhen 2 Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000048309
Gene: ENSMUSG00000035459
AA Change: D743G

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
EGF	119	156	1.85e0	SMART
EGF	167	201	2.43e1	SMART
EGF	206	244	1.43e-1	SMART
EGF	248	284	3.82e-2	SMART
EGF	333	370	2.02e-1	SMART
FAS1	414	515	1.06e-8	SMART
FAS1	561	662	3.54e-19	SMART
EGF	746	783	6.76e-3	SMART
EGF	836	873	1.31e0	SMART
EGF	877	917	2.99e-4	SMART
EGF	921	960	3.51e-1	SMART
EGF	964	1002	1.99e0	SMART
FAS1	1038	1138	1.73e-13	SMART
FAS1	1181	1276	1.83e-12	SMART
EGF	1354	1391	6.92e0	SMART
EGF	1401	1435	1.11e1	SMART
EGF	1442	1477	3.01e0	SMART
EGF	1481	1519	1.64e-1	SMART
EGF	1523	1561	1.14e0	SMART
EGF	1565	1603	5.62e0	SMART
FAS1	1638	1734	2.23e-25	SMART
FAS1	1785	1891	6.92e-22	SMART
EGF	1966	2006	1.95e1	SMART
EGF_like	1977	2017	2.46e-1	SMART
EGF	2016	2050	1.14e0	SMART
EGF	2058	2089	1.56e1	SMART
EGF	2093	2130	1.36e1	SMART
EGF	2134	2173	2.13e0	SMART
LINK	2204	2298	2.08e-29	SMART
FAS1	2363	2455	3.19e-12	SMART
transmembrane domain	2467	2489	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000160580

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000218408

Meta Mutation Damage Score

0.2447

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.5%
20x: 93.1%

Validation Efficiency

93% (99/107)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for knock-out alleles exhibit no gross abnormaities. Mice homozygous for one null allele display elevated serum hyaluronic acid levels and decreased metastasis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 92 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adcyap1r1	A	G	6: 55,457,078 (GRCm39)	T270A	probably null	Het
Adgrv1	A	T	13: 81,681,241 (GRCm39)		probably benign	Het
Aldh1b1	A	T	4: 45,803,383 (GRCm39)	D307V	probably benign	Het
Aldh3a2	A	T	11: 61,153,065 (GRCm39)	C220*	probably null	Het
Ank2	T	C	3: 126,753,444 (GRCm39)	Y279C	probably damaging	Het
Anks1	T	C	17: 28,210,351 (GRCm39)	Y444H	probably benign	Het
Asph	G	T	4: 9,531,968 (GRCm39)	T383K	probably benign	Het
Asphd1	G	T	7: 126,547,747 (GRCm39)	S185R	possibly damaging	Het
Bcl2a1d	T	A	9: 88,613,748 (GRCm39)	I9F	probably damaging	Het
Bcl2l11	T	C	2: 127,970,961 (GRCm39)		probably benign	Het
C2cd3	T	G	7: 100,062,581 (GRCm39)	S656A	possibly damaging	Het
Cd5l	T	C	3: 87,274,929 (GRCm39)	V156A	probably damaging	Het
Cdh8	G	C	8: 99,757,536 (GRCm39)	N687K	probably damaging	Het
Cdk19	A	G	10: 40,352,232 (GRCm39)	D338G	probably benign	Het
Cenpf	A	G	1: 189,390,728 (GRCm39)	C1035R	probably damaging	Het
Cep290	A	G	10: 100,384,776 (GRCm39)	R1845G	probably benign	Het
Cep295nl	G	T	11: 118,224,650 (GRCm39)	Q65K	probably damaging	Het
Ciz1	T	C	2: 32,262,300 (GRCm39)		probably benign	Het
Clasrp	T	C	7: 19,324,173 (GRCm39)	D234G	possibly damaging	Het
Dctd	C	T	8: 48,590,449 (GRCm39)		probably benign	Het
Ddr2	A	G	1: 169,832,340 (GRCm39)	V150A	probably benign	Het
Dennd10	A	G	19: 60,819,252 (GRCm39)	E120G	probably damaging	Het
Dnah7b	T	C	1: 46,120,604 (GRCm39)	S74P	probably benign	Het
Dnttip2	C	A	3: 122,078,750 (GRCm39)	A743E	probably damaging	Het
Dysf	A	T	6: 84,044,005 (GRCm39)	Q281L	possibly damaging	Het
Ece2	A	G	16: 20,462,905 (GRCm39)	E610G	probably damaging	Het
Edem3	T	G	1: 151,679,982 (GRCm39)		probably null	Het
Ext1	G	T	15: 52,955,773 (GRCm39)	N441K	probably benign	Het
Fam118a	A	G	15: 84,942,969 (GRCm39)	R333G	probably damaging	Het
Fat4	C	T	3: 38,945,754 (GRCm39)	T1549I	probably damaging	Het
Fbxo4	A	G	15: 4,005,394 (GRCm39)	V162A	probably damaging	Het
Fgd2	A	G	17: 29,592,223 (GRCm39)	H385R	possibly damaging	Het
Garnl3	A	T	2: 32,977,100 (GRCm39)	M1K	probably null	Het
Gm37267	T	G	1: 180,338,083 (GRCm39)		noncoding transcript	Het
Gpbar1	C	T	1: 74,318,702 (GRCm39)	A315V	probably damaging	Het
Grm2	T	C	9: 106,524,844 (GRCm39)	I624V	probably benign	Het
Hmcn1	T	C	1: 150,468,836 (GRCm39)	I5042V	probably benign	Het
Hnf4g	T	C	3: 3,716,448 (GRCm39)	Y291H	possibly damaging	Het
Ighm	A	G	12: 113,385,241 (GRCm39)	S240P	unknown	Het
Igkv4-91	A	G	6: 68,745,604 (GRCm39)	I98T	probably damaging	Het
Krt72	T	C	15: 101,694,469 (GRCm39)	N142S	probably damaging	Het
Kynu	T	A	2: 43,569,830 (GRCm39)	Y371N	possibly damaging	Het
Ly9	G	T	1: 171,434,898 (GRCm39)		probably benign	Het
Man1a2	C	A	3: 100,524,372 (GRCm39)	V359F	probably damaging	Het
Mast1	T	C	8: 85,647,287 (GRCm39)	I623M	probably damaging	Het
Mb	A	G	15: 76,906,687 (GRCm39)		probably null	Het
Mcm4	A	C	16: 15,452,374 (GRCm39)	L113*	probably null	Het
Mcub	C	T	3: 129,710,685 (GRCm39)	W249*	probably null	Het
Mme	T	A	3: 63,247,453 (GRCm39)	V246E	probably benign	Het
Mplkipl1	C	T	19: 61,164,364 (GRCm39)	G24R	unknown	Het
Mrpl38	A	G	11: 116,025,098 (GRCm39)	Y232H	probably damaging	Het
Myh7b	T	A	2: 155,455,420 (GRCm39)	M89K	probably benign	Het
Notch4	A	G	17: 34,796,536 (GRCm39)	S892G	possibly damaging	Het
Nt5dc3	A	G	10: 86,652,941 (GRCm39)	Y245C	probably damaging	Het
Ntn1	CCTTCTTCT	CCTTCT	11: 68,103,852 (GRCm39)		probably benign	Het
Or12d12	T	A	17: 37,611,095 (GRCm39)	T73S	probably benign	Het
Or12d14-ps1	A	T	17: 37,673,337 (GRCm39)	I107L	probably benign	Het
Or14a259	A	T	7: 86,012,692 (GRCm39)	N284K	probably damaging	Het
Or5m12	T	A	2: 85,734,715 (GRCm39)	I228F	probably benign	Het
Or8b36	G	T	9: 37,937,822 (GRCm39)	C240F	probably damaging	Het
Or8k28	A	T	2: 86,286,153 (GRCm39)	I154N	possibly damaging	Het
Palld	A	T	8: 62,002,815 (GRCm39)		probably benign	Het
Pcdhga10	T	C	18: 37,881,253 (GRCm39)	V338A	probably damaging	Het
Pcdhga11	A	G	18: 37,890,459 (GRCm39)	Y489C	probably damaging	Het
Pgm2	T	C	5: 64,261,237 (GRCm39)	Y244H	probably benign	Het
Phactr4	A	T	4: 132,105,759 (GRCm39)	S102R	probably damaging	Het
Plekha5	A	G	6: 140,471,636 (GRCm39)	Y20C	probably damaging	Het
Rdh19	A	G	10: 127,696,013 (GRCm39)	D255G	probably benign	Het
Rgs3	T	C	4: 62,549,532 (GRCm39)	V438A	probably benign	Het
Rnf186	A	G	4: 138,695,254 (GRCm39)	T265A	probably benign	Het
Ror1	T	C	4: 100,283,195 (GRCm39)	F420S	probably benign	Het
Rtkn2	A	G	10: 67,841,463 (GRCm39)	K204E	probably damaging	Het
Rundc1	A	G	11: 101,324,874 (GRCm39)	T527A	probably benign	Het
Samd4	T	C	14: 47,303,920 (GRCm39)	S301P	probably damaging	Het
Scaf1	G	A	7: 44,655,303 (GRCm39)		probably benign	Het
Srgap2	A	G	1: 131,217,210 (GRCm39)	V1034A	probably benign	Het
Stim1	A	T	7: 102,003,779 (GRCm39)	I71F	probably damaging	Het
Stk17b	T	C	1: 53,796,693 (GRCm39)	D358G	probably benign	Het
Sun2	A	G	15: 79,611,765 (GRCm39)	Y551H	probably damaging	Het
Tas2r110	A	T	6: 132,845,091 (GRCm39)	T41S	probably benign	Het
Tead3	T	A	17: 28,552,589 (GRCm39)	E268V	probably damaging	Het
Tead3	A	G	17: 28,553,962 (GRCm39)	S131P	probably benign	Het
Tepsin	A	T	11: 119,982,351 (GRCm39)	M505K	possibly damaging	Het
Trbv28	A	G	6: 41,248,668 (GRCm39)	Y66C	possibly damaging	Het
Ttc6	A	G	12: 57,749,142 (GRCm39)	Q1358R	probably damaging	Het
Ttll2	C	T	17: 7,618,998 (GRCm39)	V310I	probably benign	Het
Uaca	T	C	9: 60,753,283 (GRCm39)	V76A	probably damaging	Het
Vwf	A	T	6: 125,663,425 (GRCm39)	T2789S	probably benign	Het
Yipf4	T	C	17: 74,801,089 (GRCm39)	F136L	probably benign	Het
Zdhhc1	CGGGGG	CGGGGGG	8: 106,210,376 (GRCm39)		probably null	Het
Zfp804b	A	T	5: 6,926,479 (GRCm39)	D51E	probably damaging	Het
Zfyve9	C	T	4: 108,538,183 (GRCm39)	G969R	probably damaging	Het

Other mutations in Stab2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00091:Stab2	APN	10	86,705,070 (GRCm39)	splice site	probably null
IGL00809:Stab2	APN	10	86,684,038 (GRCm39)	splice site	probably benign
IGL00911:Stab2	APN	10	86,805,617 (GRCm39)	missense	probably damaging	1.00
IGL01347:Stab2	APN	10	86,737,567 (GRCm39)	splice site	probably null
IGL01411:Stab2	APN	10	86,815,872 (GRCm39)	splice site	probably benign
IGL01503:Stab2	APN	10	86,776,477 (GRCm39)	splice site	probably benign
IGL01599:Stab2	APN	10	86,758,759 (GRCm39)	missense	probably damaging	1.00
IGL01635:Stab2	APN	10	86,816,992 (GRCm39)	missense	probably benign	0.04
IGL01640:Stab2	APN	10	86,790,035 (GRCm39)	missense	probably benign	0.09
IGL01671:Stab2	APN	10	86,805,141 (GRCm39)	missense	possibly damaging	0.80
IGL02023:Stab2	APN	10	86,707,695 (GRCm39)	missense	possibly damaging	0.67
IGL02075:Stab2	APN	10	86,803,514 (GRCm39)	missense	possibly damaging	0.71
IGL02174:Stab2	APN	10	86,695,606 (GRCm39)	splice site	probably null
IGL02600:Stab2	APN	10	86,790,123 (GRCm39)	missense	probably damaging	1.00
IGL02666:Stab2	APN	10	86,686,766 (GRCm39)	missense	possibly damaging	0.67
IGL02668:Stab2	APN	10	86,682,027 (GRCm39)	splice site	probably benign
IGL02709:Stab2	APN	10	86,682,029 (GRCm39)	splice site	probably benign
IGL02728:Stab2	APN	10	86,692,420 (GRCm39)	missense	possibly damaging	0.95
IGL02803:Stab2	APN	10	86,786,133 (GRCm39)	splice site	probably benign
IGL02938:Stab2	APN	10	86,707,785 (GRCm39)	missense	possibly damaging	0.77
IGL03033:Stab2	APN	10	86,832,667 (GRCm39)	critical splice donor site	probably null
IGL03238:Stab2	APN	10	86,690,985 (GRCm39)	missense	probably damaging	1.00
IGL03402:Stab2	APN	10	86,805,165 (GRCm39)	missense	probably benign	0.03
prospector	UTSW	10	86,737,431 (GRCm39)	splice site	probably null
songbird	UTSW	10	86,694,016 (GRCm39)	missense	probably damaging	1.00
3-1:Stab2	UTSW	10	86,705,041 (GRCm39)	missense	probably damaging	0.96
F6893:Stab2	UTSW	10	86,691,035 (GRCm39)	missense	probably damaging	1.00
K7371:Stab2	UTSW	10	86,779,153 (GRCm39)	critical splice donor site	probably null
PIT4142001:Stab2	UTSW	10	86,703,039 (GRCm39)	missense	possibly damaging	0.94
PIT4362001:Stab2	UTSW	10	86,697,299 (GRCm39)	nonsense	probably null
R0015:Stab2	UTSW	10	86,679,481 (GRCm39)	missense	probably benign
R0254:Stab2	UTSW	10	86,733,824 (GRCm39)	missense	probably benign
R0310:Stab2	UTSW	10	86,803,477 (GRCm39)	splice site	probably benign
R0333:Stab2	UTSW	10	86,677,491 (GRCm39)	missense	probably benign
R0391:Stab2	UTSW	10	86,783,008 (GRCm39)	missense	probably benign	0.27
R0400:Stab2	UTSW	10	86,708,474 (GRCm39)	missense	probably damaging	1.00
R0433:Stab2	UTSW	10	86,679,355 (GRCm39)	splice site	probably benign
R0440:Stab2	UTSW	10	86,785,792 (GRCm39)	missense	probably benign	0.23
R0743:Stab2	UTSW	10	86,723,759 (GRCm39)	missense	probably damaging	1.00
R0847:Stab2	UTSW	10	86,805,735 (GRCm39)	missense	probably benign	0.00
R0883:Stab2	UTSW	10	86,760,314 (GRCm39)	splice site	probably benign
R1078:Stab2	UTSW	10	86,742,997 (GRCm39)	splice site	probably null
R1118:Stab2	UTSW	10	86,721,582 (GRCm39)	splice site	probably null
R1119:Stab2	UTSW	10	86,695,619 (GRCm39)	missense	possibly damaging	0.51
R1179:Stab2	UTSW	10	86,786,165 (GRCm39)	missense	probably damaging	0.98
R1440:Stab2	UTSW	10	86,697,231 (GRCm39)	splice site	probably null
R1550:Stab2	UTSW	10	86,714,790 (GRCm39)	missense	probably benign	0.01
R1616:Stab2	UTSW	10	86,721,582 (GRCm39)	splice site	probably null
R1728:Stab2	UTSW	10	86,773,903 (GRCm39)	missense	probably benign	0.41
R1768:Stab2	UTSW	10	86,838,872 (GRCm39)	missense	probably damaging	1.00
R1772:Stab2	UTSW	10	86,790,098 (GRCm39)	missense	probably benign	0.06
R1776:Stab2	UTSW	10	86,793,680 (GRCm39)	missense	possibly damaging	0.92
R1784:Stab2	UTSW	10	86,773,903 (GRCm39)	missense	probably benign	0.41
R1892:Stab2	UTSW	10	86,773,913 (GRCm39)	missense	probably damaging	0.99
R1957:Stab2	UTSW	10	86,697,334 (GRCm39)	missense	probably benign	0.13
R1972:Stab2	UTSW	10	86,796,180 (GRCm39)	missense	probably damaging	0.99
R1975:Stab2	UTSW	10	86,732,360 (GRCm39)	critical splice donor site	probably null
R1976:Stab2	UTSW	10	86,732,360 (GRCm39)	critical splice donor site	probably null
R1996:Stab2	UTSW	10	86,838,895 (GRCm39)	missense	probably damaging	1.00
R2085:Stab2	UTSW	10	86,790,023 (GRCm39)	missense	probably damaging	1.00
R2149:Stab2	UTSW	10	86,700,904 (GRCm39)	nonsense	probably null
R2169:Stab2	UTSW	10	86,723,726 (GRCm39)	missense	probably damaging	1.00
R2201:Stab2	UTSW	10	86,776,503 (GRCm39)	missense	probably benign	0.22
R2296:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2297:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2298:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2326:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2434:Stab2	UTSW	10	86,805,183 (GRCm39)	missense	possibly damaging	0.78
R2519:Stab2	UTSW	10	86,770,704 (GRCm39)	splice site	probably benign
R2696:Stab2	UTSW	10	86,697,363 (GRCm39)	missense	probably benign	0.45
R2883:Stab2	UTSW	10	86,803,550 (GRCm39)	missense	possibly damaging	0.92
R2923:Stab2	UTSW	10	86,697,325 (GRCm39)	missense	probably damaging	1.00
R3711:Stab2	UTSW	10	86,702,572 (GRCm39)	missense	probably damaging	1.00
R3787:Stab2	UTSW	10	86,805,141 (GRCm39)	missense	possibly damaging	0.50
R3834:Stab2	UTSW	10	86,785,776 (GRCm39)	missense	possibly damaging	0.87
R3970:Stab2	UTSW	10	86,714,750 (GRCm39)	missense	probably damaging	0.97
R3979:Stab2	UTSW	10	86,699,320 (GRCm39)	missense	possibly damaging	0.56
R4003:Stab2	UTSW	10	86,693,988 (GRCm39)	missense	probably damaging	1.00
R4088:Stab2	UTSW	10	86,758,049 (GRCm39)	missense	probably damaging	1.00
R4151:Stab2	UTSW	10	86,838,847 (GRCm39)	missense	probably benign	0.12
R4190:Stab2	UTSW	10	86,714,808 (GRCm39)	missense	probably damaging	0.98
R4556:Stab2	UTSW	10	86,803,543 (GRCm39)	missense	possibly damaging	0.95
R4773:Stab2	UTSW	10	86,743,235 (GRCm39)	nonsense	probably null
R4825:Stab2	UTSW	10	86,783,011 (GRCm39)	missense	probably benign	0.08
R4865:Stab2	UTSW	10	86,679,364 (GRCm39)	splice site	probably null
R4943:Stab2	UTSW	10	86,790,026 (GRCm39)	missense	probably damaging	0.99
R4981:Stab2	UTSW	10	86,796,087 (GRCm39)	missense	probably benign
R4994:Stab2	UTSW	10	86,785,771 (GRCm39)	missense	probably benign
R4999:Stab2	UTSW	10	86,773,773 (GRCm39)	missense	probably damaging	0.97
R5061:Stab2	UTSW	10	86,743,249 (GRCm39)	missense	probably damaging	1.00
R5072:Stab2	UTSW	10	86,699,422 (GRCm39)	missense	probably benign	0.23
R5073:Stab2	UTSW	10	86,699,422 (GRCm39)	missense	probably benign	0.23
R5074:Stab2	UTSW	10	86,699,422 (GRCm39)	missense	probably benign	0.23
R5134:Stab2	UTSW	10	86,707,674 (GRCm39)	splice site	probably null
R5213:Stab2	UTSW	10	86,743,061 (GRCm39)	missense	probably damaging	0.99
R5508:Stab2	UTSW	10	86,796,143 (GRCm39)	missense	probably benign	0.01
R5530:Stab2	UTSW	10	86,783,026 (GRCm39)	missense	probably benign	0.04
R5540:Stab2	UTSW	10	86,683,989 (GRCm39)	missense	probably benign	0.30
R5839:Stab2	UTSW	10	86,708,555 (GRCm39)	missense	probably damaging	0.97
R5949:Stab2	UTSW	10	86,805,713 (GRCm39)	missense	possibly damaging	0.87
R6015:Stab2	UTSW	10	86,773,906 (GRCm39)	missense	probably damaging	0.99
R6019:Stab2	UTSW	10	86,838,886 (GRCm39)	missense	probably benign	0.00
R6116:Stab2	UTSW	10	86,743,054 (GRCm39)	missense	probably damaging	1.00
R6131:Stab2	UTSW	10	86,719,642 (GRCm39)	splice site	probably null
R6209:Stab2	UTSW	10	86,758,867 (GRCm39)	missense	possibly damaging	0.94
R6243:Stab2	UTSW	10	86,743,025 (GRCm39)	missense	probably damaging	1.00
R6433:Stab2	UTSW	10	86,737,431 (GRCm39)	splice site	probably null
R6787:Stab2	UTSW	10	86,754,948 (GRCm39)	missense	probably benign	0.07
R6841:Stab2	UTSW	10	86,778,054 (GRCm39)	missense	probably damaging	1.00
R6873:Stab2	UTSW	10	86,697,230 (GRCm39)	critical splice donor site	probably null
R7025:Stab2	UTSW	10	86,686,701 (GRCm39)	missense	probably damaging	1.00
R7043:Stab2	UTSW	10	86,706,110 (GRCm39)	missense	probably damaging	0.99
R7047:Stab2	UTSW	10	86,694,016 (GRCm39)	missense	probably damaging	1.00
R7107:Stab2	UTSW	10	86,741,456 (GRCm39)	missense	possibly damaging	0.96
R7214:Stab2	UTSW	10	86,735,705 (GRCm39)	missense	probably damaging	0.99
R7271:Stab2	UTSW	10	86,838,972 (GRCm39)	splice site	probably null
R7291:Stab2	UTSW	10	86,782,084 (GRCm39)	missense	probably damaging	0.96
R7336:Stab2	UTSW	10	86,805,049 (GRCm39)	nonsense	probably null
R7432:Stab2	UTSW	10	86,721,547 (GRCm39)	missense	probably damaging	0.99
R7580:Stab2	UTSW	10	86,705,028 (GRCm39)	missense	probably benign	0.00
R7622:Stab2	UTSW	10	86,709,766 (GRCm39)	missense	possibly damaging	0.65
R7629:Stab2	UTSW	10	86,719,646 (GRCm39)	critical splice donor site	probably null
R7658:Stab2	UTSW	10	86,816,999 (GRCm39)	missense	probably benign	0.12
R7798:Stab2	UTSW	10	86,793,776 (GRCm39)	missense	probably damaging	0.98
R7835:Stab2	UTSW	10	86,708,483 (GRCm39)	missense	probably benign	0.06
R7845:Stab2	UTSW	10	86,832,758 (GRCm39)	missense	probably benign	0.09
R7863:Stab2	UTSW	10	86,808,745 (GRCm39)	missense	probably benign	0.30
R7885:Stab2	UTSW	10	86,714,776 (GRCm39)	missense	probably benign	0.03
R7904:Stab2	UTSW	10	86,790,056 (GRCm39)	nonsense	probably null
R7947:Stab2	UTSW	10	86,681,897 (GRCm39)	missense	probably benign	0.31
R7963:Stab2	UTSW	10	86,683,887 (GRCm39)	critical splice donor site	probably null
R8014:Stab2	UTSW	10	86,686,767 (GRCm39)	missense	possibly damaging	0.78
R8021:Stab2	UTSW	10	86,741,403 (GRCm39)	missense	possibly damaging	0.69
R8024:Stab2	UTSW	10	86,681,916 (GRCm39)	missense	probably benign	0.34
R8097:Stab2	UTSW	10	86,704,959 (GRCm39)	missense	possibly damaging	0.86
R8281:Stab2	UTSW	10	86,709,728 (GRCm39)	missense	probably damaging	0.98
R8462:Stab2	UTSW	10	86,803,598 (GRCm39)	missense	possibly damaging	0.79
R8670:Stab2	UTSW	10	86,776,587 (GRCm39)	missense	probably damaging	1.00
R8692:Stab2	UTSW	10	86,808,794 (GRCm39)	missense	probably damaging	0.99
R8744:Stab2	UTSW	10	86,805,213 (GRCm39)	missense	probably benign	0.32
R8745:Stab2	UTSW	10	86,805,213 (GRCm39)	missense	probably benign	0.32
R8782:Stab2	UTSW	10	86,735,685 (GRCm39)	missense	probably benign	0.00
R8875:Stab2	UTSW	10	86,832,728 (GRCm39)	missense	probably damaging	1.00
R8978:Stab2	UTSW	10	86,785,782 (GRCm39)	missense	possibly damaging	0.64
R9141:Stab2	UTSW	10	86,704,911 (GRCm39)	missense	probably damaging	1.00
R9248:Stab2	UTSW	10	86,727,481 (GRCm39)	missense	probably damaging	0.98
R9326:Stab2	UTSW	10	86,791,010 (GRCm39)	missense	probably damaging	1.00
R9426:Stab2	UTSW	10	86,704,911 (GRCm39)	missense	probably damaging	1.00
R9568:Stab2	UTSW	10	86,699,420 (GRCm39)	missense	probably damaging	1.00
R9627:Stab2	UTSW	10	86,793,704 (GRCm39)	missense	probably damaging	0.98
R9635:Stab2	UTSW	10	86,686,651 (GRCm39)	nonsense	probably null
R9648:Stab2	UTSW	10	86,692,561 (GRCm39)	frame shift	probably null
R9649:Stab2	UTSW	10	86,692,561 (GRCm39)	frame shift	probably null
R9650:Stab2	UTSW	10	86,692,561 (GRCm39)	frame shift	probably null
R9726:Stab2	UTSW	10	86,790,095 (GRCm39)	missense	probably benign	0.00
R9756:Stab2	UTSW	10	86,803,553 (GRCm39)	missense	possibly damaging	0.50
R9786:Stab2	UTSW	10	86,757,997 (GRCm39)	missense	probably benign	0.03
RF061:Stab2	UTSW	10	86,702,622 (GRCm39)	critical splice acceptor site	probably benign
X0023:Stab2	UTSW	10	86,758,062 (GRCm39)	critical splice acceptor site	probably null
X0025:Stab2	UTSW	10	86,723,680 (GRCm39)	missense	probably damaging	1.00
Z1176:Stab2	UTSW	10	86,785,778 (GRCm39)	missense	probably damaging	0.99
Z1177:Stab2	UTSW	10	86,732,460 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGACTCCTCTGCTGCAGATATTC -3'
(R):5'- CCGACAGATTGGTGGTAATGTG -3'

Sequencing Primer
(F):5'- CAGACACAATTATTTGGCTTCCTGGG -3'
(R):5'- TGTGCTAGCCAGTTCATCAGAAG -3'

Posted On

2016-03-17