Incidental Mutation 'R4887:Umodl1'
| ID |
377021 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
041979-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4887 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
31173614-31229684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 31227639 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Histidine
at position 1324
(R1324H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000110202
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000066554
AA Change: R1324H
PolyPhen 2
Score 0.056 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: R1324H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000066981
AA Change: R1209H
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: R1209H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114555
AA Change: R1324H
PolyPhen 2
Score 0.056 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: R1324H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310009B15Rik |
A |
C |
1: 138,779,903 (GRCm39) |
Y116* |
probably null |
Het |
| Abtb3 |
C |
T |
10: 85,223,242 (GRCm39) |
T17M |
unknown |
Het |
| Acer3 |
T |
C |
7: 97,906,908 (GRCm39) |
T91A |
possibly damaging |
Het |
| Acsbg3 |
A |
T |
17: 57,183,324 (GRCm39) |
I22F |
possibly damaging |
Het |
| Adam12 |
T |
C |
7: 133,774,550 (GRCm39) |
K20E |
possibly damaging |
Het |
| Adamtsl3 |
T |
C |
7: 82,223,822 (GRCm39) |
V275A |
possibly damaging |
Het |
| Afg1l |
C |
T |
10: 42,330,374 (GRCm39) |
V98I |
probably benign |
Het |
| Ajm1 |
G |
A |
2: 25,469,759 (GRCm39) |
R51C |
possibly damaging |
Het |
| Alpk1 |
C |
T |
3: 127,467,124 (GRCm39) |
G1052R |
probably damaging |
Het |
| Anln |
A |
T |
9: 22,291,484 (GRCm39) |
S115T |
possibly damaging |
Het |
| Apob |
T |
A |
12: 8,063,099 (GRCm39) |
N3827K |
probably damaging |
Het |
| Aqr |
G |
A |
2: 113,980,990 (GRCm39) |
L264F |
probably damaging |
Het |
| Arhgap33 |
T |
C |
7: 30,231,617 (GRCm39) |
S123G |
probably damaging |
Het |
| Arvcf |
C |
T |
16: 18,216,863 (GRCm39) |
R333* |
probably null |
Het |
| Brca2 |
T |
A |
5: 150,480,402 (GRCm39) |
L2724Q |
probably damaging |
Het |
| C2cd6 |
T |
A |
1: 59,133,893 (GRCm39) |
T43S |
probably benign |
Het |
| Cacna1h |
A |
G |
17: 25,596,261 (GRCm39) |
V1920A |
possibly damaging |
Het |
| Capsl |
A |
T |
15: 9,457,858 (GRCm39) |
I26F |
possibly damaging |
Het |
| Card10 |
A |
T |
15: 78,665,724 (GRCm39) |
V673E |
possibly damaging |
Het |
| Catspere2 |
A |
G |
1: 177,931,515 (GRCm39) |
Y478C |
unknown |
Het |
| Ccar1 |
A |
G |
10: 62,588,997 (GRCm39) |
S829P |
unknown |
Het |
| Ccdc121 |
A |
G |
5: 31,643,596 (GRCm39) |
I109V |
probably benign |
Het |
| Cdc42bpa |
T |
C |
1: 179,972,200 (GRCm39) |
M1334T |
possibly damaging |
Het |
| Ceacam2 |
C |
T |
7: 25,220,257 (GRCm39) |
C267Y |
probably benign |
Het |
| Cep68 |
G |
A |
11: 20,189,239 (GRCm39) |
T591M |
probably benign |
Het |
| Chil4 |
T |
C |
3: 106,111,460 (GRCm39) |
K218R |
probably benign |
Het |
| Cldn14 |
G |
T |
16: 93,716,747 (GRCm39) |
T33K |
possibly damaging |
Het |
| Copa |
T |
A |
1: 171,919,843 (GRCm39) |
C140S |
probably benign |
Het |
| Coq6 |
T |
C |
12: 84,419,070 (GRCm39) |
L358P |
probably damaging |
Het |
| Cyfip1 |
C |
T |
7: 55,521,816 (GRCm39) |
P40L |
probably damaging |
Het |
| Dennd2a |
A |
C |
6: 39,474,093 (GRCm39) |
S414A |
probably benign |
Het |
| Dpm1 |
T |
C |
2: 168,059,679 (GRCm39) |
N139S |
probably benign |
Het |
| Dpp7 |
T |
A |
2: 25,242,770 (GRCm39) |
|
probably null |
Het |
| Ednrb |
T |
C |
14: 104,057,447 (GRCm39) |
I372V |
possibly damaging |
Het |
| Edrf1 |
G |
T |
7: 133,260,339 (GRCm39) |
M83I |
probably damaging |
Het |
| Fam135a |
G |
A |
1: 24,063,334 (GRCm39) |
Q1087* |
probably null |
Het |
| Fancg |
T |
C |
4: 43,006,866 (GRCm39) |
T275A |
probably benign |
Het |
| Fbn1 |
T |
A |
2: 125,151,694 (GRCm39) |
H2520L |
probably damaging |
Het |
| Fmn2 |
T |
C |
1: 174,409,527 (GRCm39) |
S587P |
unknown |
Het |
| Foxr2 |
A |
G |
X: 151,913,312 (GRCm39) |
Q61R |
probably damaging |
Het |
| Frrs1 |
A |
G |
3: 116,696,065 (GRCm39) |
*124W |
probably null |
Het |
| Gm7535 |
T |
A |
17: 18,131,333 (GRCm39) |
|
probably benign |
Het |
| H4c1 |
T |
C |
13: 23,944,935 (GRCm39) |
D69G |
probably damaging |
Het |
| Herc3 |
T |
C |
6: 58,864,484 (GRCm39) |
V706A |
probably damaging |
Het |
| Hivep3 |
A |
G |
4: 119,980,131 (GRCm39) |
E1723G |
probably damaging |
Het |
| Igsf9b |
A |
G |
9: 27,233,946 (GRCm39) |
I382V |
probably benign |
Het |
| Ints1 |
G |
T |
5: 139,756,911 (GRCm39) |
T467N |
possibly damaging |
Het |
| Iqca1 |
G |
A |
1: 89,973,423 (GRCm39) |
T783M |
probably damaging |
Het |
| Kng1 |
A |
G |
16: 22,886,448 (GRCm39) |
K131R |
possibly damaging |
Het |
| Krt35 |
T |
C |
11: 99,983,956 (GRCm39) |
Y348C |
probably damaging |
Het |
| Ldlrad3 |
A |
G |
2: 101,943,881 (GRCm39) |
C64R |
probably damaging |
Het |
| Lilrb4b |
C |
T |
10: 51,360,616 (GRCm39) |
A272V |
possibly damaging |
Het |
| Lrrc37 |
T |
C |
11: 103,505,698 (GRCm39) |
H2090R |
probably benign |
Het |
| Ltn1 |
A |
T |
16: 87,195,697 (GRCm39) |
C1276* |
probably null |
Het |
| Matn1 |
G |
A |
4: 130,679,425 (GRCm39) |
A360T |
probably benign |
Het |
| Minpp1 |
G |
A |
19: 32,475,784 (GRCm39) |
V306I |
probably benign |
Het |
| Mkx |
G |
A |
18: 6,992,904 (GRCm39) |
R127W |
probably damaging |
Het |
| Mrpl48 |
G |
T |
7: 100,195,616 (GRCm39) |
|
probably benign |
Het |
| Ms4a2 |
A |
G |
19: 11,595,793 (GRCm39) |
L166S |
possibly damaging |
Het |
| Mtus2 |
T |
A |
5: 148,013,913 (GRCm39) |
Y235* |
probably null |
Het |
| Myh4 |
G |
T |
11: 67,131,880 (GRCm39) |
W113C |
probably damaging |
Het |
| Nav2 |
T |
A |
7: 49,198,182 (GRCm39) |
C1270* |
probably null |
Het |
| Ncoa5 |
A |
G |
2: 164,844,070 (GRCm39) |
L111P |
probably damaging |
Het |
| Nup107 |
T |
C |
10: 117,606,383 (GRCm39) |
Y453C |
probably damaging |
Het |
| Oca2 |
C |
T |
7: 55,980,106 (GRCm39) |
Q604* |
probably null |
Het |
| Or13a19 |
T |
C |
7: 139,903,014 (GRCm39) |
M134T |
probably benign |
Het |
| Or13p5 |
A |
C |
4: 118,591,885 (GRCm39) |
H53P |
probably benign |
Het |
| Or14j10 |
A |
T |
17: 37,934,782 (GRCm39) |
V248D |
probably damaging |
Het |
| Or5p58 |
T |
A |
7: 107,694,303 (GRCm39) |
N158I |
probably benign |
Het |
| Or8g33 |
T |
C |
9: 39,337,531 (GRCm39) |
T279A |
possibly damaging |
Het |
| Pde3a |
G |
T |
6: 141,416,668 (GRCm39) |
G514V |
possibly damaging |
Het |
| Pik3cb |
A |
T |
9: 98,983,381 (GRCm39) |
C76S |
probably damaging |
Het |
| Plk1 |
T |
C |
7: 121,767,828 (GRCm39) |
V411A |
probably damaging |
Het |
| Pole |
C |
T |
5: 110,472,619 (GRCm39) |
P1600L |
probably damaging |
Het |
| Prr36 |
T |
C |
8: 4,260,881 (GRCm39) |
T979A |
probably benign |
Het |
| Rdh7 |
T |
A |
10: 127,721,590 (GRCm39) |
T229S |
probably benign |
Het |
| Rnpepl1 |
A |
T |
1: 92,842,835 (GRCm39) |
T140S |
probably damaging |
Het |
| Rps6kc1 |
A |
T |
1: 190,530,891 (GRCm39) |
S947T |
probably benign |
Het |
| Rtl1 |
A |
G |
12: 109,558,138 (GRCm39) |
F1234L |
probably damaging |
Het |
| Sdc1 |
G |
A |
12: 8,841,708 (GRCm39) |
M279I |
probably damaging |
Het |
| Siae |
T |
C |
9: 37,539,096 (GRCm39) |
L169P |
possibly damaging |
Het |
| Slc22a22 |
C |
T |
15: 57,113,148 (GRCm39) |
V364I |
probably benign |
Het |
| Sltm |
G |
T |
9: 70,496,260 (GRCm39) |
V932F |
probably damaging |
Het |
| Smad1 |
A |
G |
8: 80,076,381 (GRCm39) |
L279P |
probably damaging |
Het |
| Spag17 |
G |
T |
3: 99,958,147 (GRCm39) |
G935V |
probably damaging |
Het |
| Srgap3 |
A |
G |
6: 112,723,895 (GRCm39) |
S546P |
probably damaging |
Het |
| Stxbp5 |
T |
C |
10: 9,684,844 (GRCm39) |
I519V |
probably benign |
Het |
| Syt16 |
A |
T |
12: 74,176,160 (GRCm39) |
I10F |
probably damaging |
Het |
| Trim43b |
C |
G |
9: 88,973,365 (GRCm39) |
G123R |
probably damaging |
Het |
| Ubr3 |
T |
C |
2: 69,843,475 (GRCm39) |
Y1572H |
probably damaging |
Het |
| Vmn2r44 |
A |
T |
7: 8,380,985 (GRCm39) |
W303R |
probably benign |
Het |
| Wdr93 |
T |
C |
7: 79,435,522 (GRCm39) |
Y684H |
probably damaging |
Het |
| Wnk2 |
G |
A |
13: 49,224,478 (GRCm39) |
R268C |
probably damaging |
Het |
| Zfp438 |
C |
T |
18: 5,213,776 (GRCm39) |
C394Y |
possibly damaging |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,227,724 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
31,215,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
31,215,233 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
31,217,800 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
31,215,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
31,201,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
31,192,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
31,206,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
31,205,091 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
31,187,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
31,217,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
31,208,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
31,205,473 (GRCm39) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
31,215,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
31,203,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
31,215,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
31,178,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,221,772 (GRCm39) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
31,205,478 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
31,201,232 (GRCm39) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
31,178,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
31,206,942 (GRCm39) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,227,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
31,187,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
31,201,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
31,211,128 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
31,211,062 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
31,211,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
31,208,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,221,837 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
31,203,763 (GRCm39) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
31,178,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
31,207,039 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
31,217,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
31,202,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4888:Umodl1
|
UTSW |
17 |
31,218,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
31,205,055 (GRCm39) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
31,205,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
31,203,066 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
31,199,333 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
31,201,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
31,213,761 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
31,215,256 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,221,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
31,201,325 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
31,205,121 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
31,205,273 (GRCm39) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
31,218,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
31,201,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
31,201,318 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
31,201,236 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
31,205,595 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
31,201,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
31,217,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
31,173,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
31,205,430 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
31,178,125 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
31,192,666 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
31,205,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
31,192,770 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
31,190,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
31,203,806 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
31,202,958 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
31,192,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
31,178,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
31,215,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
31,217,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
31,217,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
31,178,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCATAATTCCCCTGACCCTG -3'
(R):5'- ACAGTTCTCAGCCACTCTGG -3'
Sequencing Primer
(F):5'- TGACACCTCTCTTACCCTGAAAC -3'
(R):5'- GAGGTTTGTCAGTTACAGATCTACCC -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation