Mutagenetix > Incidental Mutation

Incidental Mutation 'R4891:Vps13b'

377321

Institutional Source

Beutler Lab

Gene Symbol

Vps13b

Ensembl Gene

ENSMUSG00000037646

Gene Name

vacuolar protein sorting 13B

Synonyms

2310042E16Rik, 1810042B05Rik, Coh1, C330002D13Rik

MMRRC Submission

042496-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4891 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

35371160-35931229 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

T to A at 35640515 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000045490 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048646]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000048646

SMART Domains

Protein: ENSMUSP00000045490
Gene: ENSMUSG00000037646

Domain	Start	End	E-Value	Type
Pfam:Chorein_N	2	120	1e-29	PFAM
low complexity region	128	137	N/A	INTRINSIC
low complexity region	143	160	N/A	INTRINSIC
low complexity region	975	984	N/A	INTRINSIC
low complexity region	1007	1018	N/A	INTRINSIC
low complexity region	1876	1883	N/A	INTRINSIC
low complexity region	2042	2054	N/A	INTRINSIC
low complexity region	2414	2423	N/A	INTRINSIC
Pfam:SHR-BD	2601	2700	8.4e-10	PFAM
low complexity region	2954	2964	N/A	INTRINSIC
Pfam:VPS13_C	3539	3706	2.6e-30	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000226579

Meta Mutation Damage Score

0.9755

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.6%
20x: 93.3%

Validation Efficiency

100% (39/39)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamts19	A	G	18: 59,033,000 (GRCm38)	Y1088C	probably damaging	Het
Cercam	C	A	2: 29,869,271 (GRCm38)		probably benign	Het
Chst1	A	G	2: 92,613,992 (GRCm38)	T270A	possibly damaging	Het
Cluh	C	T	11: 74,665,059 (GRCm38)	T816I	possibly damaging	Het
Edn3	A	G	2: 174,761,732 (GRCm38)	H91R	probably benign	Het
Fam135a	A	G	1: 24,030,328 (GRCm38)	S487P	probably benign	Het
Galns	T	A	8: 122,599,156 (GRCm38)	D212V	possibly damaging	Het
Grin2a	A	G	16: 9,657,706 (GRCm38)	V582A	possibly damaging	Het
Hs3st4	T	A	7: 124,396,829 (GRCm38)	N239K	possibly damaging	Het
Kmt2b	C	T	7: 30,576,761 (GRCm38)	W1062*	probably null	Het
Lrp1	T	C	10: 127,541,752 (GRCm38)	N4110S	probably damaging	Het
Mag	T	C	7: 30,900,368 (GRCm38)	H582R	possibly damaging	Het
Maml3	C	T	3: 51,694,510 (GRCm38)		probably benign	Het
Ndufa5	A	G	6: 24,519,247 (GRCm38)	V26A	possibly damaging	Het
Nek10	T	A	14: 14,860,986 (GRCm38)	L513M	possibly damaging	Het
Olfr206	T	A	16: 59,345,471 (GRCm38)	T77S	possibly damaging	Het
Olfr577	T	A	7: 102,973,552 (GRCm38)	I147L	probably benign	Het
Olfr71	C	T	4: 43,706,194 (GRCm38)	A125T	probably damaging	Het
Plxdc2	A	G	2: 16,712,146 (GRCm38)	H347R	probably benign	Het
Ptprn2	A	G	12: 117,233,365 (GRCm38)		probably null	Het
Rab3gap2	C	T	1: 185,259,366 (GRCm38)	A683V	probably benign	Het
Rnf157	A	G	11: 116,358,670 (GRCm38)	V240A	probably damaging	Het
Slc10a5	A	T	3: 10,334,625 (GRCm38)	V325E	possibly damaging	Het
Slc5a9	C	A	4: 111,891,744 (GRCm38)		probably null	Het
Sptbn2	C	T	19: 4,738,469 (GRCm38)	R1159C	probably damaging	Het
Stk36	A	G	1: 74,603,256 (GRCm38)	D14G	probably damaging	Het
Thap2	T	C	10: 115,372,696 (GRCm38)	K173R	probably damaging	Het
Themis2	G	T	4: 132,783,357 (GRCm38)	Q625K	probably benign	Het
Vcpip1	G	T	1: 9,748,062 (GRCm38)	P32Q	unknown	Het
Vmn1r229	A	T	17: 20,814,819 (GRCm38)	T109S	probably damaging	Het
Wdr64	A	G	1: 175,698,779 (GRCm38)		probably benign	Het
Wiz	A	G	17: 32,357,628 (GRCm38)	S642P	possibly damaging	Het
Zdhhc1	C	T	8: 105,473,017 (GRCm38)	R383Q	probably benign	Het
Zfp462	T	C	4: 55,060,055 (GRCm38)	S1194P	probably damaging	Het

Other mutations in Vps13b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00402:Vps13b	APN	15	35,926,226 (GRCm38)	missense	possibly damaging	0.52
IGL00513:Vps13b	APN	15	35,793,884 (GRCm38)	missense	probably damaging	1.00
IGL00516:Vps13b	APN	15	35,640,557 (GRCm38)	missense	probably damaging	1.00
IGL00640:Vps13b	APN	15	35,417,577 (GRCm38)	missense	probably benign
IGL00753:Vps13b	APN	15	35,372,031 (GRCm38)	missense	probably damaging	0.99
IGL00784:Vps13b	APN	15	35,846,900 (GRCm38)	missense	probably damaging	1.00
IGL01138:Vps13b	APN	15	35,446,770 (GRCm38)	splice site	probably benign
IGL01349:Vps13b	APN	15	35,793,945 (GRCm38)	missense	probably benign	0.00
IGL01403:Vps13b	APN	15	35,709,479 (GRCm38)	missense	probably benign	0.00
IGL01535:Vps13b	APN	15	35,454,957 (GRCm38)	missense	possibly damaging	0.67
IGL01571:Vps13b	APN	15	35,877,489 (GRCm38)	splice site	probably benign
IGL01642:Vps13b	APN	15	35,792,072 (GRCm38)	missense	probably benign	0.43
IGL01658:Vps13b	APN	15	35,671,333 (GRCm38)	missense	probably damaging	0.99
IGL01759:Vps13b	APN	15	35,878,789 (GRCm38)	missense	probably damaging	1.00
IGL01763:Vps13b	APN	15	35,709,799 (GRCm38)	missense	possibly damaging	0.72
IGL01906:Vps13b	APN	15	35,639,847 (GRCm38)	splice site	probably benign
IGL01982:Vps13b	APN	15	35,438,904 (GRCm38)	nonsense	probably null
IGL01997:Vps13b	APN	15	35,709,224 (GRCm38)	missense	probably damaging	1.00
IGL02041:Vps13b	APN	15	35,423,245 (GRCm38)	missense	probably damaging	0.98
IGL02073:Vps13b	APN	15	35,875,586 (GRCm38)	missense	possibly damaging	0.52
IGL02077:Vps13b	APN	15	35,910,613 (GRCm38)	missense	possibly damaging	0.68
IGL02141:Vps13b	APN	15	35,572,081 (GRCm38)	missense	probably benign	0.09
IGL02146:Vps13b	APN	15	35,646,333 (GRCm38)	missense	probably benign	0.36
IGL02197:Vps13b	APN	15	35,930,056 (GRCm38)	missense	probably benign	0.02
IGL02311:Vps13b	APN	15	35,709,514 (GRCm38)	missense	probably benign	0.08
IGL02466:Vps13b	APN	15	35,770,741 (GRCm38)	missense	possibly damaging	0.86
IGL02506:Vps13b	APN	15	35,917,162 (GRCm38)	missense	probably damaging	1.00
IGL02550:Vps13b	APN	15	35,572,096 (GRCm38)	missense	probably benign
IGL02553:Vps13b	APN	15	35,646,301 (GRCm38)	missense	probably benign	0.00
IGL02674:Vps13b	APN	15	35,639,958 (GRCm38)	missense	probably benign	0.41
IGL02690:Vps13b	APN	15	35,917,142 (GRCm38)	missense	probably damaging	1.00
IGL02731:Vps13b	APN	15	35,917,128 (GRCm38)	missense	probably benign	0.00
IGL02739:Vps13b	APN	15	35,879,900 (GRCm38)	missense	probably damaging	1.00
IGL02868:Vps13b	APN	15	35,884,519 (GRCm38)	missense	probably benign	0.03
IGL03081:Vps13b	APN	15	35,875,820 (GRCm38)	missense	probably damaging	0.97
IGL03178:Vps13b	APN	15	35,869,300 (GRCm38)	missense	probably damaging	1.00
IGL03343:Vps13b	APN	15	35,917,170 (GRCm38)	missense	possibly damaging	0.76
IGL03407:Vps13b	APN	15	35,639,866 (GRCm38)	missense	possibly damaging	0.95
IGL03410:Vps13b	APN	15	35,910,340 (GRCm38)	missense	probably benign
omlette	UTSW	15	35,671,400 (GRCm38)	missense	probably benign	0.13
swiss	UTSW	15	35,709,673 (GRCm38)	missense	possibly damaging	0.80
FR4449:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
FR4548:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
FR4737:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
FR4976:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
LCD18:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
PIT4531001:Vps13b	UTSW	15	35,878,825 (GRCm38)	missense	probably damaging	1.00
PIT4581001:Vps13b	UTSW	15	35,534,263 (GRCm38)	missense	probably damaging	1.00
PIT4618001:Vps13b	UTSW	15	35,709,240 (GRCm38)	missense	probably damaging	1.00
R0026:Vps13b	UTSW	15	35,923,301 (GRCm38)	missense	possibly damaging	0.62
R0026:Vps13b	UTSW	15	35,923,301 (GRCm38)	missense	possibly damaging	0.62
R0108:Vps13b	UTSW	15	35,572,119 (GRCm38)	missense	probably benign	0.20
R0109:Vps13b	UTSW	15	35,572,119 (GRCm38)	missense	probably benign	0.20
R0109:Vps13b	UTSW	15	35,572,119 (GRCm38)	missense	probably benign	0.20
R0116:Vps13b	UTSW	15	35,423,155 (GRCm38)	missense	probably damaging	0.99
R0123:Vps13b	UTSW	15	35,887,261 (GRCm38)	missense	probably benign	0.01
R0124:Vps13b	UTSW	15	35,576,528 (GRCm38)	critical splice donor site	probably null
R0134:Vps13b	UTSW	15	35,887,261 (GRCm38)	missense	probably benign	0.01
R0137:Vps13b	UTSW	15	35,926,219 (GRCm38)	missense	probably benign	0.06
R0195:Vps13b	UTSW	15	35,471,899 (GRCm38)	missense	probably benign	0.00
R0225:Vps13b	UTSW	15	35,887,261 (GRCm38)	missense	probably benign	0.01
R0320:Vps13b	UTSW	15	35,674,828 (GRCm38)	missense	probably damaging	0.98
R0333:Vps13b	UTSW	15	35,879,803 (GRCm38)	missense	probably damaging	1.00
R0336:Vps13b	UTSW	15	35,455,133 (GRCm38)	nonsense	probably null
R0463:Vps13b	UTSW	15	35,597,409 (GRCm38)	missense	probably damaging	0.98
R0466:Vps13b	UTSW	15	35,445,602 (GRCm38)	nonsense	probably null
R0472:Vps13b	UTSW	15	35,417,633 (GRCm38)	critical splice donor site	probably null
R0523:Vps13b	UTSW	15	35,472,050 (GRCm38)	missense	probably benign	0.20
R0602:Vps13b	UTSW	15	35,422,368 (GRCm38)	missense	probably damaging	1.00
R0612:Vps13b	UTSW	15	35,623,657 (GRCm38)	missense	probably benign	0.12
R0627:Vps13b	UTSW	15	35,371,999 (GRCm38)	nonsense	probably null
R0679:Vps13b	UTSW	15	35,709,703 (GRCm38)	missense	possibly damaging	0.73
R0742:Vps13b	UTSW	15	35,794,361 (GRCm38)	missense	probably benign	0.22
R1053:Vps13b	UTSW	15	35,652,363 (GRCm38)	missense	probably damaging	1.00
R1355:Vps13b	UTSW	15	35,422,454 (GRCm38)	missense	probably damaging	1.00
R1386:Vps13b	UTSW	15	35,923,312 (GRCm38)	missense	probably damaging	0.99
R1403:Vps13b	UTSW	15	35,709,122 (GRCm38)	splice site	probably benign
R1453:Vps13b	UTSW	15	35,422,444 (GRCm38)	missense	probably damaging	0.97
R1464:Vps13b	UTSW	15	35,709,484 (GRCm38)	missense	probably benign	0.14
R1464:Vps13b	UTSW	15	35,709,484 (GRCm38)	missense	probably benign	0.14
R1511:Vps13b	UTSW	15	35,841,573 (GRCm38)	missense	probably benign	0.00
R1511:Vps13b	UTSW	15	35,839,975 (GRCm38)	missense	probably damaging	0.99
R1513:Vps13b	UTSW	15	35,438,730 (GRCm38)	nonsense	probably null
R1536:Vps13b	UTSW	15	35,875,566 (GRCm38)	missense	probably damaging	0.98
R1537:Vps13b	UTSW	15	35,792,181 (GRCm38)	missense	possibly damaging	0.62
R1558:Vps13b	UTSW	15	35,534,319 (GRCm38)	missense	probably damaging	1.00
R1601:Vps13b	UTSW	15	35,642,436 (GRCm38)	missense	probably benign	0.11
R1653:Vps13b	UTSW	15	35,607,272 (GRCm38)	nonsense	probably null
R1695:Vps13b	UTSW	15	35,576,521 (GRCm38)	missense	probably benign	0.05
R1760:Vps13b	UTSW	15	35,884,619 (GRCm38)	missense	possibly damaging	0.54
R1785:Vps13b	UTSW	15	35,879,791 (GRCm38)	missense	probably damaging	1.00
R1786:Vps13b	UTSW	15	35,879,791 (GRCm38)	missense	probably damaging	1.00
R1803:Vps13b	UTSW	15	35,430,205 (GRCm38)	nonsense	probably null
R1804:Vps13b	UTSW	15	35,917,137 (GRCm38)	missense	probably damaging	1.00
R1808:Vps13b	UTSW	15	35,792,059 (GRCm38)	missense	probably benign	0.00
R1817:Vps13b	UTSW	15	35,910,642 (GRCm38)	missense	possibly damaging	0.86
R1818:Vps13b	UTSW	15	35,877,577 (GRCm38)	missense	probably benign	0.00
R1836:Vps13b	UTSW	15	35,910,232 (GRCm38)	missense	probably damaging	0.99
R1850:Vps13b	UTSW	15	35,674,959 (GRCm38)	splice site	probably benign
R1884:Vps13b	UTSW	15	35,430,291 (GRCm38)	splice site	probably benign
R1938:Vps13b	UTSW	15	35,709,507 (GRCm38)	missense	probably damaging	1.00
R1955:Vps13b	UTSW	15	35,925,408 (GRCm38)	critical splice donor site	probably null
R1956:Vps13b	UTSW	15	35,869,407 (GRCm38)	missense	probably damaging	1.00
R1958:Vps13b	UTSW	15	35,878,689 (GRCm38)	missense	probably damaging	0.99
R2013:Vps13b	UTSW	15	35,607,142 (GRCm38)	missense	probably damaging	0.99
R2014:Vps13b	UTSW	15	35,607,142 (GRCm38)	missense	probably damaging	0.99
R2015:Vps13b	UTSW	15	35,607,142 (GRCm38)	missense	probably damaging	0.99
R2038:Vps13b	UTSW	15	35,884,741 (GRCm38)	missense	probably damaging	1.00
R2058:Vps13b	UTSW	15	35,841,447 (GRCm38)	missense	probably damaging	1.00
R2082:Vps13b	UTSW	15	35,910,746 (GRCm38)	missense	possibly damaging	0.70
R2087:Vps13b	UTSW	15	35,597,493 (GRCm38)	missense	probably damaging	0.99
R2124:Vps13b	UTSW	15	35,646,080 (GRCm38)	missense	probably benign	0.08
R2130:Vps13b	UTSW	15	35,671,400 (GRCm38)	missense	probably benign	0.13
R2168:Vps13b	UTSW	15	35,792,188 (GRCm38)	missense	probably damaging	1.00
R2168:Vps13b	UTSW	15	35,792,189 (GRCm38)	missense	probably damaging	1.00
R2171:Vps13b	UTSW	15	35,887,197 (GRCm38)	missense	probably benign	0.44
R2221:Vps13b	UTSW	15	35,884,597 (GRCm38)	missense	probably benign
R2263:Vps13b	UTSW	15	35,646,181 (GRCm38)	missense	probably benign	0.02
R2289:Vps13b	UTSW	15	35,572,105 (GRCm38)	missense	probably damaging	1.00
R2316:Vps13b	UTSW	15	35,674,899 (GRCm38)	nonsense	probably null
R2351:Vps13b	UTSW	15	35,869,311 (GRCm38)	missense	probably damaging	1.00
R2512:Vps13b	UTSW	15	35,884,555 (GRCm38)	missense	probably benign	0.35
R3054:Vps13b	UTSW	15	35,646,361 (GRCm38)	missense	probably damaging	0.99
R3055:Vps13b	UTSW	15	35,646,361 (GRCm38)	missense	probably damaging	0.99
R3196:Vps13b	UTSW	15	35,869,395 (GRCm38)	missense	probably damaging	1.00
R3236:Vps13b	UTSW	15	35,910,304 (GRCm38)	missense	probably benign	0.40
R3404:Vps13b	UTSW	15	35,926,054 (GRCm38)	missense	probably damaging	1.00
R3722:Vps13b	UTSW	15	35,671,382 (GRCm38)	missense	probably damaging	0.99
R4077:Vps13b	UTSW	15	35,455,128 (GRCm38)	missense	probably damaging	0.99
R4153:Vps13b	UTSW	15	35,792,027 (GRCm38)	splice site	probably null
R4224:Vps13b	UTSW	15	35,876,419 (GRCm38)	missense	probably damaging	0.99
R4408:Vps13b	UTSW	15	35,709,294 (GRCm38)	missense	probably damaging	0.98
R4431:Vps13b	UTSW	15	35,770,753 (GRCm38)	missense	probably damaging	1.00
R4449:Vps13b	UTSW	15	35,876,793 (GRCm38)	missense	possibly damaging	0.86
R4508:Vps13b	UTSW	15	35,709,673 (GRCm38)	missense	possibly damaging	0.80
R4631:Vps13b	UTSW	15	35,646,132 (GRCm38)	missense	possibly damaging	0.95
R4655:Vps13b	UTSW	15	35,770,689 (GRCm38)	missense	probably benign
R4666:Vps13b	UTSW	15	35,640,544 (GRCm38)	missense	probably benign	0.13
R4684:Vps13b	UTSW	15	35,879,821 (GRCm38)	missense	probably benign
R4684:Vps13b	UTSW	15	35,841,341 (GRCm38)	missense	probably benign
R4684:Vps13b	UTSW	15	35,646,178 (GRCm38)	missense	probably damaging	0.98
R4721:Vps13b	UTSW	15	35,910,718 (GRCm38)	nonsense	probably null
R4771:Vps13b	UTSW	15	35,910,800 (GRCm38)	missense	probably damaging	1.00
R4830:Vps13b	UTSW	15	35,452,224 (GRCm38)	missense	possibly damaging	0.94
R4835:Vps13b	UTSW	15	35,869,372 (GRCm38)	missense	probably damaging	1.00
R4835:Vps13b	UTSW	15	35,910,293 (GRCm38)	missense	probably benign
R4857:Vps13b	UTSW	15	35,456,654 (GRCm38)	missense	probably benign	0.01
R5095:Vps13b	UTSW	15	35,923,202 (GRCm38)	missense	probably damaging	1.00
R5110:Vps13b	UTSW	15	35,770,809 (GRCm38)	missense	probably damaging	0.99
R5147:Vps13b	UTSW	15	35,456,678 (GRCm38)	missense	probably benign	0.32
R5153:Vps13b	UTSW	15	35,422,453 (GRCm38)	missense	probably damaging	0.99
R5257:Vps13b	UTSW	15	35,794,421 (GRCm38)	missense	possibly damaging	0.75
R5258:Vps13b	UTSW	15	35,794,421 (GRCm38)	missense	possibly damaging	0.75
R5296:Vps13b	UTSW	15	35,876,413 (GRCm38)	missense	probably damaging	1.00
R5386:Vps13b	UTSW	15	35,640,528 (GRCm38)	critical splice acceptor site	probably null
R5396:Vps13b	UTSW	15	35,886,948 (GRCm38)	missense	probably damaging	0.99
R5412:Vps13b	UTSW	15	35,533,385 (GRCm38)	missense	probably damaging	1.00
R5488:Vps13b	UTSW	15	35,770,542 (GRCm38)	missense	probably benign
R5489:Vps13b	UTSW	15	35,770,542 (GRCm38)	missense	probably benign
R5503:Vps13b	UTSW	15	35,452,166 (GRCm38)	missense	probably damaging	0.97
R5575:Vps13b	UTSW	15	35,929,919 (GRCm38)	missense	probably damaging	1.00
R5781:Vps13b	UTSW	15	35,794,035 (GRCm38)	missense	probably damaging	0.97
R5872:Vps13b	UTSW	15	35,869,351 (GRCm38)	missense	possibly damaging	0.56
R5876:Vps13b	UTSW	15	35,917,061 (GRCm38)	missense	probably damaging	0.99
R5994:Vps13b	UTSW	15	35,875,772 (GRCm38)	missense	probably damaging	1.00
R6031:Vps13b	UTSW	15	35,471,968 (GRCm38)	missense	probably damaging	1.00
R6031:Vps13b	UTSW	15	35,471,968 (GRCm38)	missense	probably damaging	1.00
R6045:Vps13b	UTSW	15	35,671,316 (GRCm38)	missense	probably damaging	0.99
R6143:Vps13b	UTSW	15	35,668,738 (GRCm38)	missense	probably damaging	0.99
R6147:Vps13b	UTSW	15	35,930,031 (GRCm38)	missense	probably benign	0.16
R6218:Vps13b	UTSW	15	35,770,464 (GRCm38)	missense	probably benign	0.00
R6447:Vps13b	UTSW	15	35,572,126 (GRCm38)	missense	probably benign	0.02
R6555:Vps13b	UTSW	15	35,846,847 (GRCm38)	missense	probably damaging	1.00
R6578:Vps13b	UTSW	15	35,446,101 (GRCm38)	missense	probably damaging	0.99
R6640:Vps13b	UTSW	15	35,617,696 (GRCm38)	missense	possibly damaging	0.93
R6645:Vps13b	UTSW	15	35,910,305 (GRCm38)	missense	probably benign	0.25
R6711:Vps13b	UTSW	15	35,887,249 (GRCm38)	missense	probably damaging	1.00
R6727:Vps13b	UTSW	15	35,770,683 (GRCm38)	missense	probably benign	0.19
R6737:Vps13b	UTSW	15	35,910,611 (GRCm38)	missense	probably damaging	1.00
R6844:Vps13b	UTSW	15	35,877,590 (GRCm38)	missense	probably benign	0.06
R6849:Vps13b	UTSW	15	35,905,309 (GRCm38)	missense	probably damaging	1.00
R6861:Vps13b	UTSW	15	35,576,395 (GRCm38)	missense	probably damaging	0.99
R6938:Vps13b	UTSW	15	35,423,198 (GRCm38)	missense	probably damaging	0.99
R6943:Vps13b	UTSW	15	35,448,689 (GRCm38)	missense	possibly damaging	0.95
R6989:Vps13b	UTSW	15	35,448,581 (GRCm38)	missense	probably benign	0.02
R7092:Vps13b	UTSW	15	35,640,634 (GRCm38)	missense	probably damaging	1.00
R7232:Vps13b	UTSW	15	35,877,557 (GRCm38)	missense	probably damaging	1.00
R7307:Vps13b	UTSW	15	35,841,545 (GRCm38)	missense	probably benign
R7400:Vps13b	UTSW	15	35,378,900 (GRCm38)	missense	probably damaging	1.00
R7414:Vps13b	UTSW	15	35,910,827 (GRCm38)	missense	probably damaging	1.00
R7497:Vps13b	UTSW	15	35,876,697 (GRCm38)	missense	probably benign	0.38
R7500:Vps13b	UTSW	15	35,910,524 (GRCm38)	missense	possibly damaging	0.74
R7603:Vps13b	UTSW	15	35,576,439 (GRCm38)	missense	probably damaging	0.98
R7605:Vps13b	UTSW	15	35,770,646 (GRCm38)	missense	probably damaging	0.97
R7849:Vps13b	UTSW	15	35,423,232 (GRCm38)	missense	probably damaging	0.99
R7984:Vps13b	UTSW	15	35,879,913 (GRCm38)	missense	probably benign
R8094:Vps13b	UTSW	15	35,668,906 (GRCm38)	critical splice donor site	probably null
R8097:Vps13b	UTSW	15	35,709,346 (GRCm38)	missense	probably benign	0.38
R8131:Vps13b	UTSW	15	35,372,109 (GRCm38)	critical splice donor site	probably null
R8139:Vps13b	UTSW	15	35,607,272 (GRCm38)	nonsense	probably null
R8174:Vps13b	UTSW	15	35,709,310 (GRCm38)	nonsense	probably null
R8225:Vps13b	UTSW	15	35,794,382 (GRCm38)	missense	probably damaging	0.99
R8239:Vps13b	UTSW	15	35,597,404 (GRCm38)	missense	probably damaging	1.00
R8244:Vps13b	UTSW	15	35,917,203 (GRCm38)	missense	probably damaging	1.00
R8303:Vps13b	UTSW	15	35,639,917 (GRCm38)	missense	probably damaging	1.00
R8311:Vps13b	UTSW	15	35,886,954 (GRCm38)	missense	probably benign	0.37
R8443:Vps13b	UTSW	15	35,455,100 (GRCm38)	missense	probably benign
R8494:Vps13b	UTSW	15	35,422,448 (GRCm38)	missense	probably damaging	0.99
R8499:Vps13b	UTSW	15	35,841,320 (GRCm38)	missense	probably damaging	1.00
R8506:Vps13b	UTSW	15	35,446,745 (GRCm38)	missense	probably benign	0.31
R8559:Vps13b	UTSW	15	35,876,642 (GRCm38)	missense	probably damaging	1.00
R8686:Vps13b	UTSW	15	35,925,389 (GRCm38)	missense	probably damaging	0.99
R8782:Vps13b	UTSW	15	35,422,337 (GRCm38)	missense	possibly damaging	0.93
R8806:Vps13b	UTSW	15	35,472,066 (GRCm38)	critical splice donor site	probably benign
R8824:Vps13b	UTSW	15	35,533,299 (GRCm38)	missense	probably damaging	0.99
R9024:Vps13b	UTSW	15	35,923,324 (GRCm38)	missense	probably damaging	0.97
R9038:Vps13b	UTSW	15	35,875,785 (GRCm38)	missense	possibly damaging	0.70
R9054:Vps13b	UTSW	15	35,422,391 (GRCm38)	missense	probably damaging	1.00
R9091:Vps13b	UTSW	15	35,770,773 (GRCm38)	missense	probably benign	0.13
R9129:Vps13b	UTSW	15	35,448,647 (GRCm38)	missense	probably damaging	1.00
R9214:Vps13b	UTSW	15	35,623,746 (GRCm38)	missense	probably damaging	0.99
R9237:Vps13b	UTSW	15	35,841,333 (GRCm38)	missense	probably damaging	1.00
R9256:Vps13b	UTSW	15	35,623,779 (GRCm38)	missense	possibly damaging	0.95
R9270:Vps13b	UTSW	15	35,770,773 (GRCm38)	missense	probably benign	0.13
R9279:Vps13b	UTSW	15	35,572,144 (GRCm38)	missense	probably damaging	0.97
R9291:Vps13b	UTSW	15	35,846,913 (GRCm38)	missense	probably damaging	1.00
R9342:Vps13b	UTSW	15	35,455,054 (GRCm38)	missense	possibly damaging	0.94
R9404:Vps13b	UTSW	15	35,876,419 (GRCm38)	missense	probably damaging	1.00
R9488:Vps13b	UTSW	15	35,447,734 (GRCm38)	missense	possibly damaging	0.77
R9509:Vps13b	UTSW	15	35,841,311 (GRCm38)	missense	possibly damaging	0.79
R9610:Vps13b	UTSW	15	35,642,409 (GRCm38)	missense	possibly damaging	0.85
R9611:Vps13b	UTSW	15	35,642,409 (GRCm38)	missense	possibly damaging	0.85
R9658:Vps13b	UTSW	15	35,623,628 (GRCm38)	missense	probably benign	0.00
R9674:Vps13b	UTSW	15	35,607,234 (GRCm38)	missense	probably damaging	0.98
R9696:Vps13b	UTSW	15	35,674,887 (GRCm38)	missense	possibly damaging	0.56
R9767:Vps13b	UTSW	15	35,910,257 (GRCm38)	missense	probably damaging	1.00
R9797:Vps13b	UTSW	15	35,674,876 (GRCm38)	missense	probably damaging	1.00
RF020:Vps13b	UTSW	15	35,925,406 (GRCm38)	missense	probably null	1.00
X0026:Vps13b	UTSW	15	35,910,646 (GRCm38)	missense	probably damaging	1.00
X0028:Vps13b	UTSW	15	35,709,431 (GRCm38)	missense	probably benign	0.00
Z1177:Vps13b	UTSW	15	35,668,885 (GRCm38)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- CAGAGATCCTTGGCTGGTAAC -3'
(R):5'- TGTAAGCAGCTCTAACAGACC -3'

Sequencing Primer
(F):5'- GATCCTTGGCTGGTAACACATTGATC -3'
(R):5'- TAACAGACCCAGCGCTCCTG -3'

Posted On

2016-03-17