Incidental Mutation 'R4893:Pnpla7'
| ID |
377373 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pnpla7
|
| Ensembl Gene |
ENSMUSG00000036833 |
| Gene Name |
patatin-like phospholipase domain containing 7 |
| Synonyms |
NRE, E430013P11Rik |
| MMRRC Submission |
042498-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.151)
|
| Stock # |
R4893 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
24866045-24944069 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 24943688 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Stop codon
at position 1314
(Y1314*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000044078
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000006646]
[ENSMUST00000045295]
[ENSMUST00000074422]
[ENSMUST00000100334]
[ENSMUST00000102931]
[ENSMUST00000114386]
[ENSMUST00000114388]
[ENSMUST00000152122]
[ENSMUST00000137913]
[ENSMUST00000116574]
[ENSMUST00000140737]
[ENSMUST00000132172]
[ENSMUST00000144520]
[ENSMUST00000155601]
|
| AlphaFold |
A2AJ88 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000006646
|
| SMART Domains |
Protein: ENSMUSP00000006646
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
281 |
292 |
N/A |
INTRINSIC |
|
low complexity region
|
361 |
375 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000045295
AA Change: Y1314*
|
| SMART Domains |
Protein: ENSMUSP00000044078
Gene: ENSMUSG00000036833
AA Change: Y1314*
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
59 |
66 |
N/A |
INTRINSIC |
|
cNMP
|
170 |
295 |
2.06e-12 |
SMART |
|
low complexity region
|
439 |
444 |
N/A |
INTRINSIC |
|
cNMP
|
481 |
600 |
1.16e-6 |
SMART |
|
cNMP
|
603 |
716 |
1.55e-7 |
SMART |
|
Pfam:Patatin
|
950 |
1116 |
3.2e-24 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074422
|
| SMART Domains |
Protein: ENSMUSP00000074022
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
258 |
269 |
N/A |
INTRINSIC |
|
low complexity region
|
338 |
352 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100334
|
| SMART Domains |
Protein: ENSMUSP00000097908
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
283 |
294 |
N/A |
INTRINSIC |
|
low complexity region
|
363 |
377 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102931
|
| SMART Domains |
Protein: ENSMUSP00000099995
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
260 |
271 |
N/A |
INTRINSIC |
|
low complexity region
|
340 |
354 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114386
|
| SMART Domains |
Protein: ENSMUSP00000110028
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
310 |
324 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114388
|
| SMART Domains |
Protein: ENSMUSP00000110030
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
331 |
345 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141584
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132082
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141866
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140733
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000138536
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135328
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128517
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152122
|
| SMART Domains |
Protein: ENSMUSP00000121580
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
Pfam:IQ
|
62 |
80 |
2.5e-4 |
PFAM |
|
low complexity region
|
114 |
125 |
N/A |
INTRINSIC |
|
low complexity region
|
194 |
208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137913
|
| SMART Domains |
Protein: ENSMUSP00000141577
Gene: ENSMUSG00000036833
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
10 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
33 |
40 |
N/A |
INTRINSIC |
|
Pfam:cNMP_binding
|
162 |
200 |
2.7e-5 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000116574
|
| SMART Domains |
Protein: ENSMUSP00000112273
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
260 |
271 |
N/A |
INTRINSIC |
|
low complexity region
|
340 |
354 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000134744
|
| SMART Domains |
Protein: ENSMUSP00000120376
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
12 |
N/A |
INTRINSIC |
|
low complexity region
|
113 |
127 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140737
|
| SMART Domains |
Protein: ENSMUSP00000141410
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132172
|
| SMART Domains |
Protein: ENSMUSP00000116106
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144520
|
| SMART Domains |
Protein: ENSMUSP00000141583
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
283 |
294 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155909
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000175104
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154359
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155601
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Human patatin-like phospholipases, such as PNPLA7, have been implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson et al., 2006 [PubMed 16799181]).[supplied by OMIM, Jun 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 69 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700030J22Rik |
A |
G |
8: 117,697,904 (GRCm39) |
I401T |
probably damaging |
Het |
| 2700049A03Rik |
A |
T |
12: 71,211,321 (GRCm39) |
E685V |
possibly damaging |
Het |
| 2700049A03Rik |
G |
T |
12: 71,211,320 (GRCm39) |
E685* |
probably null |
Het |
| Acss1 |
C |
A |
2: 150,471,786 (GRCm39) |
V323F |
probably damaging |
Het |
| Adgrf3 |
T |
G |
5: 30,405,476 (GRCm39) |
D286A |
probably benign |
Het |
| Akap5 |
T |
C |
12: 76,376,743 (GRCm39) |
V718A |
probably damaging |
Het |
| Ankk1 |
A |
G |
9: 49,326,983 (GRCm39) |
V732A |
probably benign |
Het |
| Antxr2 |
T |
A |
5: 98,151,931 (GRCm39) |
D180V |
probably damaging |
Het |
| Arfgef2 |
T |
G |
2: 166,708,876 (GRCm39) |
F1063V |
probably benign |
Het |
| Ascl5 |
A |
T |
1: 135,978,917 (GRCm39) |
I126F |
probably damaging |
Het |
| Aspm |
T |
A |
1: 139,417,577 (GRCm39) |
|
probably null |
Het |
| Atf6b |
T |
C |
17: 34,867,586 (GRCm39) |
S100P |
probably damaging |
Het |
| Baz2a |
C |
A |
10: 127,959,284 (GRCm39) |
H1266Q |
possibly damaging |
Het |
| Cdh4 |
A |
T |
2: 179,489,212 (GRCm39) |
|
probably benign |
Het |
| Celsr3 |
C |
G |
9: 108,726,620 (GRCm39) |
S3283C |
probably damaging |
Het |
| Clca4b |
C |
T |
3: 144,630,934 (GRCm39) |
V309M |
possibly damaging |
Het |
| Cnbd2 |
T |
C |
2: 156,207,104 (GRCm39) |
Y436H |
probably damaging |
Het |
| Csnk1a1 |
T |
C |
18: 61,718,372 (GRCm39) |
|
probably benign |
Het |
| Cstf1 |
C |
T |
2: 172,222,444 (GRCm39) |
R401C |
probably damaging |
Het |
| Cul3 |
A |
G |
1: 80,266,567 (GRCm39) |
I117T |
probably damaging |
Het |
| Dlgap3 |
A |
G |
4: 127,088,776 (GRCm39) |
D124G |
probably damaging |
Het |
| Dnah12 |
A |
G |
14: 26,431,325 (GRCm39) |
D381G |
possibly damaging |
Het |
| Dtna |
T |
C |
18: 23,702,724 (GRCm39) |
L85P |
probably damaging |
Het |
| Ephb2 |
A |
G |
4: 136,387,064 (GRCm39) |
I722T |
probably damaging |
Het |
| Epn3 |
A |
T |
11: 94,382,822 (GRCm39) |
F421I |
probably damaging |
Het |
| Fam83f |
T |
A |
15: 80,576,156 (GRCm39) |
L269H |
probably damaging |
Het |
| Fhip2a |
T |
A |
19: 57,370,188 (GRCm39) |
H477Q |
probably benign |
Het |
| Gata4 |
G |
A |
14: 63,439,045 (GRCm39) |
A139V |
probably benign |
Het |
| Glce |
T |
C |
9: 61,975,777 (GRCm39) |
D241G |
probably benign |
Het |
| Gm17728 |
A |
T |
17: 9,641,063 (GRCm39) |
I58F |
probably benign |
Het |
| Inhba |
A |
T |
13: 16,201,134 (GRCm39) |
D232V |
possibly damaging |
Het |
| Itgb2l |
C |
A |
16: 96,229,021 (GRCm39) |
R394L |
probably benign |
Het |
| Klhl14 |
T |
C |
18: 21,690,992 (GRCm39) |
Y486C |
probably damaging |
Het |
| Krt1 |
A |
G |
15: 101,758,555 (GRCm39) |
I203T |
probably damaging |
Het |
| Lims2 |
T |
C |
18: 32,074,864 (GRCm39) |
|
probably null |
Het |
| Lrrc31 |
T |
G |
3: 30,733,446 (GRCm39) |
I423L |
probably benign |
Het |
| Map7d1 |
C |
T |
4: 126,127,015 (GRCm39) |
D732N |
unknown |
Het |
| Mau2 |
A |
T |
8: 70,483,290 (GRCm39) |
|
probably null |
Het |
| Mbtps1 |
G |
A |
8: 120,244,932 (GRCm39) |
R840W |
probably damaging |
Het |
| Morn3 |
T |
C |
5: 123,175,745 (GRCm39) |
I214M |
probably damaging |
Het |
| Mrpl44 |
A |
G |
1: 79,755,582 (GRCm39) |
K63E |
probably damaging |
Het |
| Muc20 |
T |
C |
16: 32,615,042 (GRCm39) |
T112A |
possibly damaging |
Het |
| Myo6 |
T |
A |
9: 80,136,159 (GRCm39) |
L94Q |
probably damaging |
Het |
| Nos1 |
C |
A |
5: 118,090,942 (GRCm39) |
T1423K |
possibly damaging |
Het |
| Or2l13 |
A |
G |
16: 19,305,653 (GRCm39) |
T22A |
probably benign |
Het |
| Or2t1 |
T |
C |
14: 14,328,852 (GRCm38) |
V247A |
probably damaging |
Het |
| Pdzd2 |
T |
C |
15: 12,385,429 (GRCm39) |
T1114A |
probably benign |
Het |
| Pgm2 |
T |
C |
5: 64,263,283 (GRCm39) |
V310A |
probably benign |
Het |
| Pi4ka |
T |
C |
16: 17,194,900 (GRCm39) |
E166G |
probably benign |
Het |
| Pign |
A |
T |
1: 105,574,436 (GRCm39) |
D303E |
probably damaging |
Het |
| Pik3c3 |
G |
T |
18: 30,415,053 (GRCm39) |
V149L |
probably benign |
Het |
| Pkd1l3 |
A |
T |
8: 110,365,026 (GRCm39) |
Y1126F |
probably benign |
Het |
| Pkd2l1 |
T |
A |
19: 44,142,210 (GRCm39) |
Q516L |
probably benign |
Het |
| Pnliprp2 |
C |
A |
19: 58,759,853 (GRCm39) |
Q355K |
probably benign |
Het |
| Ppp1r1b |
A |
G |
11: 98,246,170 (GRCm39) |
T51A |
possibly damaging |
Het |
| Prkcd |
A |
T |
14: 30,321,382 (GRCm39) |
S544T |
probably damaging |
Het |
| Pusl1 |
G |
A |
4: 155,973,998 (GRCm39) |
T252I |
probably benign |
Het |
| Rnf44 |
A |
G |
13: 54,829,745 (GRCm39) |
|
probably null |
Het |
| Slc24a2 |
A |
T |
4: 87,145,145 (GRCm39) |
V303E |
probably damaging |
Het |
| Slc28a2 |
T |
A |
2: 122,285,697 (GRCm39) |
|
probably null |
Het |
| Sox8 |
T |
C |
17: 25,787,963 (GRCm39) |
D162G |
probably damaging |
Het |
| Spag1 |
T |
C |
15: 36,197,992 (GRCm39) |
|
probably null |
Het |
| Taar6 |
T |
C |
10: 23,861,298 (GRCm39) |
I83V |
probably benign |
Het |
| Tes |
T |
A |
6: 17,104,595 (GRCm39) |
C359S |
probably damaging |
Het |
| Vmn2r4 |
A |
T |
3: 64,313,676 (GRCm39) |
L435H |
probably damaging |
Het |
| Zfhx3 |
G |
T |
8: 109,683,639 (GRCm39) |
D3693Y |
unknown |
Het |
| Zfp931 |
G |
A |
2: 177,709,996 (GRCm39) |
P130L |
probably damaging |
Het |
| Zfr |
T |
G |
15: 12,136,628 (GRCm39) |
V95G |
unknown |
Het |
| Zw10 |
A |
G |
9: 48,985,325 (GRCm39) |
E587G |
possibly damaging |
Het |
|
| Other mutations in Pnpla7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00421:Pnpla7
|
APN |
2 |
24,866,327 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00765:Pnpla7
|
APN |
2 |
24,870,236 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01576:Pnpla7
|
APN |
2 |
24,906,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01626:Pnpla7
|
APN |
2 |
24,940,905 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
IGL01844:Pnpla7
|
APN |
2 |
24,940,985 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02280:Pnpla7
|
APN |
2 |
24,901,589 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02629:Pnpla7
|
APN |
2 |
24,940,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02642:Pnpla7
|
APN |
2 |
24,940,288 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL02931:Pnpla7
|
APN |
2 |
24,905,241 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL03162:Pnpla7
|
APN |
2 |
24,905,301 (GRCm39) |
unclassified |
probably benign |
|
|
PIT4495001:Pnpla7
|
UTSW |
2 |
24,932,151 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0047:Pnpla7
|
UTSW |
2 |
24,901,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0047:Pnpla7
|
UTSW |
2 |
24,901,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0064:Pnpla7
|
UTSW |
2 |
24,887,239 (GRCm39) |
nonsense |
probably null |
|
|
R0064:Pnpla7
|
UTSW |
2 |
24,887,239 (GRCm39) |
nonsense |
probably null |
|
|
R0309:Pnpla7
|
UTSW |
2 |
24,877,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0541:Pnpla7
|
UTSW |
2 |
24,885,305 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0556:Pnpla7
|
UTSW |
2 |
24,942,313 (GRCm39) |
splice site |
probably null |
|
|
R0565:Pnpla7
|
UTSW |
2 |
24,870,129 (GRCm39) |
splice site |
probably benign |
|
|
R0830:Pnpla7
|
UTSW |
2 |
24,887,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0865:Pnpla7
|
UTSW |
2 |
24,872,135 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0893:Pnpla7
|
UTSW |
2 |
24,887,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0969:Pnpla7
|
UTSW |
2 |
24,940,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1102:Pnpla7
|
UTSW |
2 |
24,886,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1551:Pnpla7
|
UTSW |
2 |
24,937,720 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1572:Pnpla7
|
UTSW |
2 |
24,905,263 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R1623:Pnpla7
|
UTSW |
2 |
24,942,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1876:Pnpla7
|
UTSW |
2 |
24,930,985 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1898:Pnpla7
|
UTSW |
2 |
24,943,796 (GRCm39) |
unclassified |
probably benign |
|
|
R1909:Pnpla7
|
UTSW |
2 |
24,887,300 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1973:Pnpla7
|
UTSW |
2 |
24,906,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2230:Pnpla7
|
UTSW |
2 |
24,941,610 (GRCm39) |
unclassified |
probably benign |
|
|
R2381:Pnpla7
|
UTSW |
2 |
24,870,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2655:Pnpla7
|
UTSW |
2 |
24,942,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3125:Pnpla7
|
UTSW |
2 |
24,932,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4223:Pnpla7
|
UTSW |
2 |
24,872,126 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4411:Pnpla7
|
UTSW |
2 |
24,941,716 (GRCm39) |
nonsense |
probably null |
|
|
R4573:Pnpla7
|
UTSW |
2 |
24,940,885 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4674:Pnpla7
|
UTSW |
2 |
24,942,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4841:Pnpla7
|
UTSW |
2 |
24,870,064 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4842:Pnpla7
|
UTSW |
2 |
24,870,064 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4941:Pnpla7
|
UTSW |
2 |
24,887,276 (GRCm39) |
splice site |
probably null |
|
|
R5116:Pnpla7
|
UTSW |
2 |
24,911,982 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5126:Pnpla7
|
UTSW |
2 |
24,870,056 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5138:Pnpla7
|
UTSW |
2 |
24,931,115 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5169:Pnpla7
|
UTSW |
2 |
24,940,321 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5188:Pnpla7
|
UTSW |
2 |
24,887,312 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5288:Pnpla7
|
UTSW |
2 |
24,931,031 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5307:Pnpla7
|
UTSW |
2 |
24,911,964 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5339:Pnpla7
|
UTSW |
2 |
24,892,949 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5384:Pnpla7
|
UTSW |
2 |
24,931,031 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5385:Pnpla7
|
UTSW |
2 |
24,931,031 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5479:Pnpla7
|
UTSW |
2 |
24,909,453 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5640:Pnpla7
|
UTSW |
2 |
24,893,013 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5662:Pnpla7
|
UTSW |
2 |
24,942,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5751:Pnpla7
|
UTSW |
2 |
24,871,790 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5874:Pnpla7
|
UTSW |
2 |
24,901,661 (GRCm39) |
missense |
probably benign |
|
|
R6284:Pnpla7
|
UTSW |
2 |
24,906,630 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6351:Pnpla7
|
UTSW |
2 |
24,901,576 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6513:Pnpla7
|
UTSW |
2 |
24,906,550 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7193:Pnpla7
|
UTSW |
2 |
24,941,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7503:Pnpla7
|
UTSW |
2 |
24,873,544 (GRCm39) |
nonsense |
probably null |
|
|
R7526:Pnpla7
|
UTSW |
2 |
24,888,678 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7791:Pnpla7
|
UTSW |
2 |
24,942,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8262:Pnpla7
|
UTSW |
2 |
24,873,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8283:Pnpla7
|
UTSW |
2 |
24,940,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8993:Pnpla7
|
UTSW |
2 |
24,943,431 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9086:Pnpla7
|
UTSW |
2 |
24,929,709 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9229:Pnpla7
|
UTSW |
2 |
24,873,503 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9494:Pnpla7
|
UTSW |
2 |
24,942,390 (GRCm39) |
nonsense |
probably null |
|
|
R9651:Pnpla7
|
UTSW |
2 |
24,892,931 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Pnpla7
|
UTSW |
2 |
24,888,771 (GRCm39) |
missense |
probably null |
0.06 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGCTGACTTCCAGAGCACTG -3'
(R):5'- TAAGGAATGGGTGCAGCCTC -3'
Sequencing Primer
(F):5'- CACTGGGATTGAGCTAGACTCTGAC -3'
(R):5'- ATGGGTGCAGCCTCAGTCTAAG -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation