Mutagenetix > Incidental Mutation

Incidental Mutation 'R4906:Sec16a'

378160

Institutional Source

Beutler Lab

Gene Symbol

Sec16a

Ensembl Gene

ENSMUSG00000026924

Gene Name

SEC16 homolog A, endoplasmic reticulum export factor

Synonyms

C230052J16Rik

MMRRC Submission

042508-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.959) question?

Stock #

R4906 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

26299443-26335228 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

A to T at 26331979 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s): [ENSMUST00000091252] [ENSMUST00000114082]

AlphaFold

E9QAT4

Predicted Effect

unknown
Transcript: ENSMUST00000091252
AA Change: V12E

SMART Domains

Protein: ENSMUSP00000088796
Gene: ENSMUSG00000026924
AA Change: V12E

Domain	Start	End	E-Value	Type
low complexity region	2	21	N/A	INTRINSIC
low complexity region	204	221	N/A	INTRINSIC
low complexity region	243	254	N/A	INTRINSIC
low complexity region	371	382	N/A	INTRINSIC
low complexity region	537	561	N/A	INTRINSIC
low complexity region	608	621	N/A	INTRINSIC
low complexity region	760	777	N/A	INTRINSIC
low complexity region	1096	1105	N/A	INTRINSIC
low complexity region	1134	1150	N/A	INTRINSIC
low complexity region	1185	1195	N/A	INTRINSIC
low complexity region	1370	1392	N/A	INTRINSIC
Pfam:Sec16	1463	1565	3.1e-24	PFAM
low complexity region	1600	1614	N/A	INTRINSIC
Pfam:Sec16_C	1635	1898	2.3e-39	PFAM
low complexity region	2109	2124	N/A	INTRINSIC
low complexity region	2165	2177	N/A	INTRINSIC
low complexity region	2187	2197	N/A	INTRINSIC
low complexity region	2227	2242	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000114082
AA Change: V12E

SMART Domains

Protein: ENSMUSP00000109716
Gene: ENSMUSG00000026924
AA Change: V12E

Domain	Start	End	E-Value	Type
low complexity region	2	21	N/A	INTRINSIC
low complexity region	204	221	N/A	INTRINSIC
low complexity region	243	254	N/A	INTRINSIC
low complexity region	371	382	N/A	INTRINSIC
low complexity region	537	561	N/A	INTRINSIC
low complexity region	608	621	N/A	INTRINSIC
low complexity region	760	777	N/A	INTRINSIC
low complexity region	1096	1105	N/A	INTRINSIC
low complexity region	1134	1150	N/A	INTRINSIC
low complexity region	1185	1195	N/A	INTRINSIC
low complexity region	1370	1392	N/A	INTRINSIC
Pfam:Sec16	1464	1564	2.6e-10	PFAM
low complexity region	1600	1614	N/A	INTRINSIC
Pfam:Sec16_C	1636	1887	6.8e-45	PFAM
low complexity region	2109	2124	N/A	INTRINSIC
low complexity region	2165	2177	N/A	INTRINSIC
low complexity region	2187	2197	N/A	INTRINSIC
low complexity region	2227	2242	N/A	INTRINSIC
low complexity region	2310	2320	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000133463

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000139144

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000151521

Predicted Effect

probably benign
Transcript: ENSMUST00000153996

SMART Domains

Protein: ENSMUSP00000121179
Gene: ENSMUSG00000026924

Domain	Start	End	E-Value	Type
low complexity region	12	29	N/A	INTRINSIC
low complexity region	116	125	N/A	INTRINSIC
low complexity region	154	170	N/A	INTRINSIC
low complexity region	205	215	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000155252

Coding Region Coverage

1x: 98.9%
3x: 98.1%
10x: 95.7%
20x: 90.5%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that forms part of the Sec16 complex. This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Feb 2013]

Allele List at MGI

Other mutations in this stock

Total: 91 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
5330417H12Rik	T	C	7: 107,223,897 (GRCm39)		probably benign	Het
Ablim2	C	T	5: 35,959,766 (GRCm39)	R73C	possibly damaging	Het
Adgrf2	T	C	17: 43,022,084 (GRCm39)	I247V	probably benign	Het
Adgrv1	A	G	13: 81,418,857 (GRCm39)		probably null	Het
Ankrd22	T	A	19: 34,126,752 (GRCm39)	K26I	possibly damaging	Het
Arhgap32	T	A	9: 32,156,552 (GRCm39)		probably null	Het
Armc10	A	G	5: 21,866,522 (GRCm39)	Y262C	probably damaging	Het
Arrb2	A	G	11: 70,330,725 (GRCm39)	D374G	probably benign	Het
Ascc3	C	T	10: 50,625,227 (GRCm39)	R1675C	probably damaging	Het
Atg5	T	C	10: 44,239,046 (GRCm39)	*276R	probably null	Het
Bcl11b	G	A	12: 107,882,968 (GRCm39)	T377M	probably damaging	Het
C1s2	C	A	6: 124,612,073 (GRCm39)	E104*	probably null	Het
Carf	A	T	1: 60,180,526 (GRCm39)	H316L	probably damaging	Het
Ccdc77	A	T	6: 120,311,796 (GRCm39)	I234N	probably damaging	Het
Cd300c2	A	T	11: 114,887,826 (GRCm39)	V192E	possibly damaging	Het
Cep72	G	A	13: 74,207,584 (GRCm39)	R62C	probably damaging	Het
Clasp1	T	A	1: 118,436,640 (GRCm39)	L308*	probably null	Het
Clec2g	A	G	6: 128,956,411 (GRCm39)	S25G	probably benign	Het
Cngb1	T	C	8: 95,978,601 (GRCm39)	M1046V	probably damaging	Het
Cobll1	A	T	2: 64,928,037 (GRCm39)	D1095E	probably benign	Het
Cpeb2	A	G	5: 43,402,005 (GRCm39)	H662R	possibly damaging	Het
Cps1	A	T	1: 67,178,922 (GRCm39)	T45S	probably benign	Het
Cspp1	A	G	1: 10,152,553 (GRCm39)	Q368R	possibly damaging	Het
Dcaf6	C	A	1: 165,239,032 (GRCm39)		probably null	Het
Dcst1	T	C	3: 89,257,814 (GRCm39)	Y652C	possibly damaging	Het
Elf5	T	G	2: 103,279,918 (GRCm39)	Y225*	probably null	Het
Ermap	A	C	4: 119,046,015 (GRCm39)		probably benign	Het
Fam186b	A	T	15: 99,169,202 (GRCm39)	V915D	probably damaging	Het
Fbxo34	C	A	14: 47,766,911 (GRCm39)	N90K	probably benign	Het
Flnc	A	G	6: 29,447,524 (GRCm39)	E1109G	probably damaging	Het
Flt1	C	A	5: 147,620,749 (GRCm39)	A132S	probably benign	Het
Gabpb2	A	G	3: 95,097,947 (GRCm39)	V242A	probably benign	Het
Gas2l3	CACTCGTCATACT	CACT	10: 89,266,820 (GRCm39)		probably benign	Het
Gm21798	A	T	15: 64,689,732 (GRCm39)		probably benign	Het
Gpr179	A	T	11: 97,237,487 (GRCm39)	S345T	possibly damaging	Het
Gusb	A	T	5: 130,026,959 (GRCm39)	F377L	probably damaging	Het
Hnrnpu	T	C	1: 178,156,938 (GRCm39)		probably benign	Het
Htr3b	C	T	9: 48,848,348 (GRCm39)		probably null	Het
Iqub	A	T	6: 24,501,368 (GRCm39)	V194D	probably damaging	Het
Itga2b	A	G	11: 102,351,985 (GRCm39)	V504A	probably benign	Het
Itga4	T	A	2: 79,118,592 (GRCm39)	F430L	probably damaging	Het
Jcad	C	A	18: 4,673,762 (GRCm39)	P508H	probably damaging	Het
Jph1	T	C	1: 17,161,835 (GRCm39)	T276A	probably damaging	Het
Kansl2	A	G	15: 98,429,771 (GRCm39)	F87S	possibly damaging	Het
Kdm1b	T	C	13: 47,216,620 (GRCm39)		probably null	Het
Kif5b	C	T	18: 6,220,930 (GRCm39)	D393N	probably benign	Het
Kmt2d	A	T	15: 98,747,420 (GRCm39)		probably benign	Het
Krt75	A	G	15: 101,478,674 (GRCm39)	I320T	probably damaging	Het
Lhfpl7	T	A	5: 113,386,036 (GRCm39)	M161K	probably benign	Het
Lipo5	T	C	19: 33,443,348 (GRCm39)	N156S	unknown	Het
Mblac2	A	C	13: 81,859,706 (GRCm39)	Q19P	probably null	Het
Mdfic2	A	T	6: 98,215,080 (GRCm39)	M181K	probably damaging	Het
Mfsd4b3-ps	T	C	10: 39,824,056 (GRCm39)	H68R	probably damaging	Het
Mzb1	A	T	18: 35,781,006 (GRCm39)		probably null	Het
Nup210l	T	A	3: 90,077,337 (GRCm39)	I891N	probably benign	Het
Nwd1	G	A	8: 73,398,841 (GRCm39)	R667Q	probably damaging	Het
Oas1h	C	T	5: 121,005,172 (GRCm39)	Q207*	probably null	Het
Or13c7d	A	T	4: 43,770,476 (GRCm39)	F178L	possibly damaging	Het
Pcdh15	C	T	10: 74,340,625 (GRCm39)	R1120*	probably null	Het
Pfkl	A	G	10: 77,824,144 (GRCm39)	L748P	probably damaging	Het
Phldb2	T	A	16: 45,571,758 (GRCm39)	K473N	probably damaging	Het
Rapgef6	G	A	11: 54,443,662 (GRCm39)	V82I	probably damaging	Het
Rfc3	A	T	5: 151,570,960 (GRCm39)	L112Q	probably damaging	Het
Rsph6a	T	A	7: 18,801,997 (GRCm39)	C349S	possibly damaging	Het
Septin14	T	A	5: 129,770,030 (GRCm39)	Y222F	probably benign	Het
Skor2	T	C	18: 76,947,990 (GRCm39)	S571P	possibly damaging	Het
Slc13a5	T	A	11: 72,148,244 (GRCm39)	M264L	probably damaging	Het
Slc45a3	T	A	1: 131,909,315 (GRCm39)	V504E	probably damaging	Het
Smg1	C	T	7: 117,751,631 (GRCm39)		probably benign	Het
Smim20	A	G	5: 53,434,503 (GRCm39)	N45S	probably null	Het
Spp2	A	T	1: 88,339,991 (GRCm39)	S111C	probably damaging	Het
Sspo	A	G	6: 48,442,664 (GRCm39)		probably null	Het
Sycp2	C	T	2: 178,045,450 (GRCm39)		probably null	Het
Tas2r113	A	G	6: 132,870,521 (GRCm39)	N183S	possibly damaging	Het
Tcaf2	A	T	6: 42,606,679 (GRCm39)	M425K	probably benign	Het
Tdrp	A	G	8: 14,003,845 (GRCm39)	V164A	possibly damaging	Het
Tmbim1	A	G	1: 74,328,568 (GRCm39)	F298S	probably damaging	Het
Tmem89	A	G	9: 108,743,829 (GRCm39)		probably benign	Het
Trpm2	G	T	10: 77,768,023 (GRCm39)	C825*	probably null	Het
Tsc1	A	G	2: 28,565,201 (GRCm39)	E421G	possibly damaging	Het
Usp24	T	C	4: 106,245,834 (GRCm39)	I1364T	probably benign	Het
Vmn1r52	G	A	6: 90,155,930 (GRCm39)	G78E	possibly damaging	Het
Vmn2r73	T	G	7: 85,506,829 (GRCm39)	I828L	probably damaging	Het
Vwa5b1	A	T	4: 138,338,058 (GRCm39)	D87E	probably benign	Het
Zfp1010	T	C	2: 176,957,223 (GRCm39)	T92A	possibly damaging	Het
Zfp451	A	T	1: 33,844,465 (GRCm39)	D47E	probably damaging	Het
Zfp821	A	G	8: 110,450,841 (GRCm39)	E278G	probably damaging	Het
Zfp930	A	T	8: 69,681,597 (GRCm39)	T430S	probably benign	Het
Zfp994	G	T	17: 22,419,448 (GRCm39)	Y500*	probably null	Het
Zmat3	A	T	3: 32,397,836 (GRCm39)	I142N	probably damaging	Het
Zzef1	T	A	11: 72,792,214 (GRCm39)	I2266N	probably damaging	Het

Other mutations in Sec16a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00337:Sec16a	APN	2	26,329,499 (GRCm39)	missense	probably benign	0.15
IGL00435:Sec16a	APN	2	26,320,113 (GRCm39)	missense	probably benign	0.00
IGL00469:Sec16a	APN	2	26,318,312 (GRCm39)	missense	probably damaging	1.00
IGL01622:Sec16a	APN	2	26,328,915 (GRCm39)	missense	probably benign	0.00
IGL01623:Sec16a	APN	2	26,328,915 (GRCm39)	missense	probably benign	0.00
IGL02158:Sec16a	APN	2	26,306,644 (GRCm39)	critical splice donor site	probably null
IGL02188:Sec16a	APN	2	26,326,020 (GRCm39)	missense	probably damaging	1.00
IGL02445:Sec16a	APN	2	26,312,052 (GRCm39)	missense	probably benign
IGL02568:Sec16a	APN	2	26,326,054 (GRCm39)	missense	probably damaging	1.00
IGL02710:Sec16a	APN	2	26,320,142 (GRCm39)	missense	possibly damaging	0.75
IGL02735:Sec16a	APN	2	26,318,149 (GRCm39)	splice site	probably benign
IGL02964:Sec16a	APN	2	26,309,735 (GRCm39)	missense	probably benign	0.00
IGL03027:Sec16a	APN	2	26,313,601 (GRCm39)	missense	probably benign	0.13
IGL03073:Sec16a	APN	2	26,329,195 (GRCm39)	missense	probably benign	0.02
IGL03297:Sec16a	APN	2	26,329,202 (GRCm39)	missense	probably benign	0.05
IGL03339:Sec16a	APN	2	26,325,945 (GRCm39)	missense	probably benign
H8562:Sec16a	UTSW	2	26,331,517 (GRCm39)	missense	probably benign
IGL03050:Sec16a	UTSW	2	26,305,759 (GRCm39)	missense	probably damaging	1.00
PIT4486001:Sec16a	UTSW	2	26,315,785 (GRCm39)	missense
R0039:Sec16a	UTSW	2	26,313,926 (GRCm39)	missense	probably benign	0.03
R0095:Sec16a	UTSW	2	26,315,772 (GRCm39)	splice site	probably null
R0095:Sec16a	UTSW	2	26,315,772 (GRCm39)	splice site	probably null
R0189:Sec16a	UTSW	2	26,314,426 (GRCm39)	splice site	probably null
R0255:Sec16a	UTSW	2	26,321,198 (GRCm39)	missense	probably damaging	0.97
R0278:Sec16a	UTSW	2	26,318,328 (GRCm39)	missense	probably damaging	1.00
R0739:Sec16a	UTSW	2	26,331,063 (GRCm39)	missense	possibly damaging	0.94
R0743:Sec16a	UTSW	2	26,309,734 (GRCm39)	missense	possibly damaging	0.67
R1446:Sec16a	UTSW	2	26,313,579 (GRCm39)	missense	probably benign	0.00
R1466:Sec16a	UTSW	2	26,321,169 (GRCm39)	missense	probably damaging	0.98
R1466:Sec16a	UTSW	2	26,321,169 (GRCm39)	missense	probably damaging	0.98
R1501:Sec16a	UTSW	2	26,330,057 (GRCm39)	missense	probably benign	0.16
R1524:Sec16a	UTSW	2	26,318,394 (GRCm39)	missense	probably damaging	1.00
R1584:Sec16a	UTSW	2	26,321,169 (GRCm39)	missense	probably damaging	0.98
R1649:Sec16a	UTSW	2	26,315,536 (GRCm39)	missense	probably damaging	1.00
R1744:Sec16a	UTSW	2	26,329,198 (GRCm39)	missense	probably damaging	1.00
R1959:Sec16a	UTSW	2	26,320,144 (GRCm39)	missense	probably benign	0.00
R1973:Sec16a	UTSW	2	26,316,501 (GRCm39)	missense	probably damaging	1.00
R2005:Sec16a	UTSW	2	26,329,092 (GRCm39)	missense	probably benign	0.27
R2073:Sec16a	UTSW	2	26,330,251 (GRCm39)	missense	probably damaging	1.00
R2074:Sec16a	UTSW	2	26,330,251 (GRCm39)	missense	probably damaging	1.00
R2075:Sec16a	UTSW	2	26,330,251 (GRCm39)	missense	probably damaging	1.00
R2151:Sec16a	UTSW	2	26,303,757 (GRCm39)	intron	probably benign
R2472:Sec16a	UTSW	2	26,329,948 (GRCm39)	missense	probably damaging	1.00
R2512:Sec16a	UTSW	2	26,329,037 (GRCm39)	missense	probably benign	0.00
R2520:Sec16a	UTSW	2	26,331,368 (GRCm39)	nonsense	probably null
R2571:Sec16a	UTSW	2	26,329,343 (GRCm39)	missense	probably benign	0.08
R3105:Sec16a	UTSW	2	26,328,433 (GRCm39)	missense	probably benign	0.14
R3508:Sec16a	UTSW	2	26,315,862 (GRCm39)	missense	probably damaging	1.00
R3809:Sec16a	UTSW	2	26,331,825 (GRCm39)	missense	possibly damaging	0.71
R3912:Sec16a	UTSW	2	26,304,399 (GRCm39)	missense	probably damaging	0.97
R4292:Sec16a	UTSW	2	26,312,167 (GRCm39)	missense	probably benign	0.01
R4293:Sec16a	UTSW	2	26,312,167 (GRCm39)	missense	probably benign	0.01
R4294:Sec16a	UTSW	2	26,312,167 (GRCm39)	missense	probably benign	0.01
R4576:Sec16a	UTSW	2	26,321,131 (GRCm39)	nonsense	probably null
R4611:Sec16a	UTSW	2	26,331,817 (GRCm39)	missense	probably benign	0.04
R4627:Sec16a	UTSW	2	26,321,080 (GRCm39)	splice site	probably null
R4627:Sec16a	UTSW	2	26,319,405 (GRCm39)	missense	probably damaging	1.00
R4662:Sec16a	UTSW	2	26,320,582 (GRCm39)	missense	probably damaging	1.00
R4665:Sec16a	UTSW	2	26,302,970 (GRCm39)	intron	probably benign
R4967:Sec16a	UTSW	2	26,302,883 (GRCm39)	missense	probably benign	0.00
R4983:Sec16a	UTSW	2	26,329,531 (GRCm39)	missense	probably benign
R5033:Sec16a	UTSW	2	26,309,661 (GRCm39)	missense	probably benign	0.00
R5251:Sec16a	UTSW	2	26,329,357 (GRCm39)	missense	probably benign	0.00
R5391:Sec16a	UTSW	2	26,330,044 (GRCm39)	missense	possibly damaging	0.82
R5457:Sec16a	UTSW	2	26,330,280 (GRCm39)	missense	probably benign	0.01
R5530:Sec16a	UTSW	2	26,329,264 (GRCm39)	missense	probably benign	0.00
R5645:Sec16a	UTSW	2	26,329,907 (GRCm39)	missense	probably benign	0.01
R5661:Sec16a	UTSW	2	26,329,649 (GRCm39)	missense	probably benign	0.01
R5770:Sec16a	UTSW	2	26,304,402 (GRCm39)	missense	probably damaging	0.99
R5830:Sec16a	UTSW	2	26,330,853 (GRCm39)	missense	probably benign	0.15
R5866:Sec16a	UTSW	2	26,309,650 (GRCm39)	missense	probably benign	0.00
R5875:Sec16a	UTSW	2	26,323,379 (GRCm39)	missense	probably damaging	1.00
R5906:Sec16a	UTSW	2	26,328,843 (GRCm39)	missense	possibly damaging	0.63
R5922:Sec16a	UTSW	2	26,305,651 (GRCm39)	missense	probably benign	0.05
R6076:Sec16a	UTSW	2	26,313,954 (GRCm39)	missense	probably damaging	1.00
R6091:Sec16a	UTSW	2	26,316,482 (GRCm39)	missense	probably damaging	1.00
R6295:Sec16a	UTSW	2	26,318,253 (GRCm39)	missense	probably damaging	1.00
R6302:Sec16a	UTSW	2	26,315,817 (GRCm39)	missense	probably damaging	1.00
R6309:Sec16a	UTSW	2	26,328,583 (GRCm39)	missense	probably benign	0.00
R6459:Sec16a	UTSW	2	26,313,512 (GRCm39)	missense	probably benign	0.04
R6520:Sec16a	UTSW	2	26,316,118 (GRCm39)	missense	probably damaging	1.00
R6631:Sec16a	UTSW	2	26,329,969 (GRCm39)	missense	probably damaging	1.00
R6657:Sec16a	UTSW	2	26,315,876 (GRCm39)	nonsense	probably null
R6750:Sec16a	UTSW	2	26,330,030 (GRCm39)	missense	probably benign	0.00
R6852:Sec16a	UTSW	2	26,331,431 (GRCm39)	missense	probably damaging	0.99
R6860:Sec16a	UTSW	2	26,320,124 (GRCm39)	missense	probably damaging	1.00
R6967:Sec16a	UTSW	2	26,320,498 (GRCm39)	missense	probably damaging	1.00
R6968:Sec16a	UTSW	2	26,320,498 (GRCm39)	missense	probably damaging	1.00
R6970:Sec16a	UTSW	2	26,320,498 (GRCm39)	missense	probably damaging	1.00
R6991:Sec16a	UTSW	2	26,320,498 (GRCm39)	missense	probably damaging	1.00
R6993:Sec16a	UTSW	2	26,313,586 (GRCm39)	missense	probably damaging	0.99
R7009:Sec16a	UTSW	2	26,326,014 (GRCm39)	nonsense	probably null
R7057:Sec16a	UTSW	2	26,315,277 (GRCm39)	missense	probably damaging	1.00
R7186:Sec16a	UTSW	2	26,330,715 (GRCm39)	nonsense	probably null
R7227:Sec16a	UTSW	2	26,328,935 (GRCm39)	missense	probably benign	0.01
R7234:Sec16a	UTSW	2	26,329,780 (GRCm39)	missense	probably damaging	1.00
R7259:Sec16a	UTSW	2	26,331,604 (GRCm39)	missense	probably benign	0.00
R7326:Sec16a	UTSW	2	26,329,729 (GRCm39)	missense	unknown
R7371:Sec16a	UTSW	2	26,331,734 (GRCm39)	missense	probably benign
R7388:Sec16a	UTSW	2	26,318,376 (GRCm39)	missense
R7414:Sec16a	UTSW	2	26,313,643 (GRCm39)	missense
R7417:Sec16a	UTSW	2	26,311,409 (GRCm39)	missense
R7501:Sec16a	UTSW	2	26,331,863 (GRCm39)	missense	probably damaging	1.00
R7558:Sec16a	UTSW	2	26,329,746 (GRCm39)	missense
R7696:Sec16a	UTSW	2	26,305,645 (GRCm39)	critical splice donor site	probably null
R7981:Sec16a	UTSW	2	26,311,384 (GRCm39)	critical splice donor site	probably null
R8117:Sec16a	UTSW	2	26,331,441 (GRCm39)	missense	probably benign	0.00
R8131:Sec16a	UTSW	2	26,300,958 (GRCm39)	missense
R8163:Sec16a	UTSW	2	26,306,433 (GRCm39)	missense
R8825:Sec16a	UTSW	2	26,313,586 (GRCm39)	missense
R8855:Sec16a	UTSW	2	26,329,852 (GRCm39)	missense	probably benign	0.16
R9165:Sec16a	UTSW	2	26,313,645 (GRCm39)	missense
R9216:Sec16a	UTSW	2	26,304,401 (GRCm39)	missense
R9283:Sec16a	UTSW	2	26,313,904 (GRCm39)	missense
R9506:Sec16a	UTSW	2	26,319,384 (GRCm39)	critical splice donor site	probably null
R9581:Sec16a	UTSW	2	26,328,647 (GRCm39)	missense
R9772:Sec16a	UTSW	2	26,329,417 (GRCm39)	missense	possibly damaging	0.87
X0011:Sec16a	UTSW	2	26,305,655 (GRCm39)	missense	probably damaging	1.00
X0034:Sec16a	UTSW	2	26,306,709 (GRCm39)	missense	probably benign	0.07
X0062:Sec16a	UTSW	2	26,306,709 (GRCm39)	missense	probably benign	0.07
Z1088:Sec16a	UTSW	2	26,329,105 (GRCm39)	missense	probably damaging	0.99
Z1176:Sec16a	UTSW	2	26,328,760 (GRCm39)	missense
Z1177:Sec16a	UTSW	2	26,329,333 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- GGCTGCTTTTGGATGAACTTCC -3'
(R):5'- CCTTGTCCCTGATGATGTGG -3'

Sequencing Primer
(F):5'- GCTTTTGGATGAACTTCCTACTG -3'
(R):5'- CCCTGATGATGTGGGGCTG -3'

Posted On

2016-04-15