Incidental Mutation 'R4906:Arhgap32'
| ID |
378206 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arhgap32
|
| Ensembl Gene |
ENSMUSG00000041444 |
| Gene Name |
Rho GTPase activating protein 32 |
| Synonyms |
p200RhoGAP, Grit, PX-RICS, GC-GAP, 3426406O18Rik |
| MMRRC Submission |
042508-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4906 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
32027432-32179742 bp(+) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
T to A
at 32156552 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138584
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000168954]
[ENSMUST00000168954]
[ENSMUST00000174641]
[ENSMUST00000174641]
[ENSMUST00000182802]
[ENSMUST00000183121]
[ENSMUST00000183121]
|
| AlphaFold |
Q811P8 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000168954
|
| SMART Domains |
Protein: ENSMUSP00000128448
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000168954
|
| SMART Domains |
Protein: ENSMUSP00000128448
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000174641
|
| SMART Domains |
Protein: ENSMUSP00000133898
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PX
|
132 |
226 |
5.6e-7 |
PFAM |
|
SH3
|
262 |
320 |
7.4e-11 |
SMART |
|
RhoGAP
|
383 |
564 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
581 |
647 |
9e-31 |
BLAST |
|
low complexity region
|
867 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1038 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1323 |
N/A |
INTRINSIC |
|
low complexity region
|
1346 |
1357 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1442 |
N/A |
INTRINSIC |
|
low complexity region
|
1653 |
1666 |
N/A |
INTRINSIC |
|
low complexity region
|
2040 |
2049 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000174641
|
| SMART Domains |
Protein: ENSMUSP00000133898
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PX
|
132 |
226 |
5.6e-7 |
PFAM |
|
SH3
|
262 |
320 |
7.4e-11 |
SMART |
|
RhoGAP
|
383 |
564 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
581 |
647 |
9e-31 |
BLAST |
|
low complexity region
|
867 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1038 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1323 |
N/A |
INTRINSIC |
|
low complexity region
|
1346 |
1357 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1442 |
N/A |
INTRINSIC |
|
low complexity region
|
1653 |
1666 |
N/A |
INTRINSIC |
|
low complexity region
|
2040 |
2049 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000174730
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000182802
|
| SMART Domains |
Protein: ENSMUSP00000138145
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000183121
|
| SMART Domains |
Protein: ENSMUSP00000138584
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RhoGAP
|
37 |
92 |
5.9e-11 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000183121
|
| SMART Domains |
Protein: ENSMUSP00000138584
Gene: ENSMUSG00000041444
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RhoGAP
|
37 |
92 |
5.9e-11 |
PFAM |
|
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 98.1%
- 10x: 95.7%
- 20x: 90.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a null mutation are fertile but display abnormal neurite growth. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5330417H12Rik |
T |
C |
7: 107,223,897 (GRCm39) |
|
probably benign |
Het |
| Ablim2 |
C |
T |
5: 35,959,766 (GRCm39) |
R73C |
possibly damaging |
Het |
| Adgrf2 |
T |
C |
17: 43,022,084 (GRCm39) |
I247V |
probably benign |
Het |
| Adgrv1 |
A |
G |
13: 81,418,857 (GRCm39) |
|
probably null |
Het |
| Ankrd22 |
T |
A |
19: 34,126,752 (GRCm39) |
K26I |
possibly damaging |
Het |
| Armc10 |
A |
G |
5: 21,866,522 (GRCm39) |
Y262C |
probably damaging |
Het |
| Arrb2 |
A |
G |
11: 70,330,725 (GRCm39) |
D374G |
probably benign |
Het |
| Ascc3 |
C |
T |
10: 50,625,227 (GRCm39) |
R1675C |
probably damaging |
Het |
| Atg5 |
T |
C |
10: 44,239,046 (GRCm39) |
*276R |
probably null |
Het |
| Bcl11b |
G |
A |
12: 107,882,968 (GRCm39) |
T377M |
probably damaging |
Het |
| C1s2 |
C |
A |
6: 124,612,073 (GRCm39) |
E104* |
probably null |
Het |
| Carf |
A |
T |
1: 60,180,526 (GRCm39) |
H316L |
probably damaging |
Het |
| Ccdc77 |
A |
T |
6: 120,311,796 (GRCm39) |
I234N |
probably damaging |
Het |
| Cd300c2 |
A |
T |
11: 114,887,826 (GRCm39) |
V192E |
possibly damaging |
Het |
| Cep72 |
G |
A |
13: 74,207,584 (GRCm39) |
R62C |
probably damaging |
Het |
| Clasp1 |
T |
A |
1: 118,436,640 (GRCm39) |
L308* |
probably null |
Het |
| Clec2g |
A |
G |
6: 128,956,411 (GRCm39) |
S25G |
probably benign |
Het |
| Cngb1 |
T |
C |
8: 95,978,601 (GRCm39) |
M1046V |
probably damaging |
Het |
| Cobll1 |
A |
T |
2: 64,928,037 (GRCm39) |
D1095E |
probably benign |
Het |
| Cpeb2 |
A |
G |
5: 43,402,005 (GRCm39) |
H662R |
possibly damaging |
Het |
| Cps1 |
A |
T |
1: 67,178,922 (GRCm39) |
T45S |
probably benign |
Het |
| Cspp1 |
A |
G |
1: 10,152,553 (GRCm39) |
Q368R |
possibly damaging |
Het |
| Dcaf6 |
C |
A |
1: 165,239,032 (GRCm39) |
|
probably null |
Het |
| Dcst1 |
T |
C |
3: 89,257,814 (GRCm39) |
Y652C |
possibly damaging |
Het |
| Elf5 |
T |
G |
2: 103,279,918 (GRCm39) |
Y225* |
probably null |
Het |
| Ermap |
A |
C |
4: 119,046,015 (GRCm39) |
|
probably benign |
Het |
| Fam186b |
A |
T |
15: 99,169,202 (GRCm39) |
V915D |
probably damaging |
Het |
| Fbxo34 |
C |
A |
14: 47,766,911 (GRCm39) |
N90K |
probably benign |
Het |
| Flnc |
A |
G |
6: 29,447,524 (GRCm39) |
E1109G |
probably damaging |
Het |
| Flt1 |
C |
A |
5: 147,620,749 (GRCm39) |
A132S |
probably benign |
Het |
| Gabpb2 |
A |
G |
3: 95,097,947 (GRCm39) |
V242A |
probably benign |
Het |
| Gas2l3 |
CACTCGTCATACT |
CACT |
10: 89,266,820 (GRCm39) |
|
probably benign |
Het |
| Gm21798 |
A |
T |
15: 64,689,732 (GRCm39) |
|
probably benign |
Het |
| Gpr179 |
A |
T |
11: 97,237,487 (GRCm39) |
S345T |
possibly damaging |
Het |
| Gusb |
A |
T |
5: 130,026,959 (GRCm39) |
F377L |
probably damaging |
Het |
| Hnrnpu |
T |
C |
1: 178,156,938 (GRCm39) |
|
probably benign |
Het |
| Htr3b |
C |
T |
9: 48,848,348 (GRCm39) |
|
probably null |
Het |
| Iqub |
A |
T |
6: 24,501,368 (GRCm39) |
V194D |
probably damaging |
Het |
| Itga2b |
A |
G |
11: 102,351,985 (GRCm39) |
V504A |
probably benign |
Het |
| Itga4 |
T |
A |
2: 79,118,592 (GRCm39) |
F430L |
probably damaging |
Het |
| Jcad |
C |
A |
18: 4,673,762 (GRCm39) |
P508H |
probably damaging |
Het |
| Jph1 |
T |
C |
1: 17,161,835 (GRCm39) |
T276A |
probably damaging |
Het |
| Kansl2 |
A |
G |
15: 98,429,771 (GRCm39) |
F87S |
possibly damaging |
Het |
| Kdm1b |
T |
C |
13: 47,216,620 (GRCm39) |
|
probably null |
Het |
| Kif5b |
C |
T |
18: 6,220,930 (GRCm39) |
D393N |
probably benign |
Het |
| Kmt2d |
A |
T |
15: 98,747,420 (GRCm39) |
|
probably benign |
Het |
| Krt75 |
A |
G |
15: 101,478,674 (GRCm39) |
I320T |
probably damaging |
Het |
| Lhfpl7 |
T |
A |
5: 113,386,036 (GRCm39) |
M161K |
probably benign |
Het |
| Lipo5 |
T |
C |
19: 33,443,348 (GRCm39) |
N156S |
unknown |
Het |
| Mblac2 |
A |
C |
13: 81,859,706 (GRCm39) |
Q19P |
probably null |
Het |
| Mdfic2 |
A |
T |
6: 98,215,080 (GRCm39) |
M181K |
probably damaging |
Het |
| Mfsd4b3-ps |
T |
C |
10: 39,824,056 (GRCm39) |
H68R |
probably damaging |
Het |
| Mzb1 |
A |
T |
18: 35,781,006 (GRCm39) |
|
probably null |
Het |
| Nup210l |
T |
A |
3: 90,077,337 (GRCm39) |
I891N |
probably benign |
Het |
| Nwd1 |
G |
A |
8: 73,398,841 (GRCm39) |
R667Q |
probably damaging |
Het |
| Oas1h |
C |
T |
5: 121,005,172 (GRCm39) |
Q207* |
probably null |
Het |
| Or13c7d |
A |
T |
4: 43,770,476 (GRCm39) |
F178L |
possibly damaging |
Het |
| Pcdh15 |
C |
T |
10: 74,340,625 (GRCm39) |
R1120* |
probably null |
Het |
| Pfkl |
A |
G |
10: 77,824,144 (GRCm39) |
L748P |
probably damaging |
Het |
| Phldb2 |
T |
A |
16: 45,571,758 (GRCm39) |
K473N |
probably damaging |
Het |
| Rapgef6 |
G |
A |
11: 54,443,662 (GRCm39) |
V82I |
probably damaging |
Het |
| Rfc3 |
A |
T |
5: 151,570,960 (GRCm39) |
L112Q |
probably damaging |
Het |
| Rsph6a |
T |
A |
7: 18,801,997 (GRCm39) |
C349S |
possibly damaging |
Het |
| Sec16a |
A |
T |
2: 26,331,979 (GRCm39) |
|
probably benign |
Het |
| Septin14 |
T |
A |
5: 129,770,030 (GRCm39) |
Y222F |
probably benign |
Het |
| Skor2 |
T |
C |
18: 76,947,990 (GRCm39) |
S571P |
possibly damaging |
Het |
| Slc13a5 |
T |
A |
11: 72,148,244 (GRCm39) |
M264L |
probably damaging |
Het |
| Slc45a3 |
T |
A |
1: 131,909,315 (GRCm39) |
V504E |
probably damaging |
Het |
| Smg1 |
C |
T |
7: 117,751,631 (GRCm39) |
|
probably benign |
Het |
| Smim20 |
A |
G |
5: 53,434,503 (GRCm39) |
N45S |
probably null |
Het |
| Spp2 |
A |
T |
1: 88,339,991 (GRCm39) |
S111C |
probably damaging |
Het |
| Sspo |
A |
G |
6: 48,442,664 (GRCm39) |
|
probably null |
Het |
| Sycp2 |
C |
T |
2: 178,045,450 (GRCm39) |
|
probably null |
Het |
| Tas2r113 |
A |
G |
6: 132,870,521 (GRCm39) |
N183S |
possibly damaging |
Het |
| Tcaf2 |
A |
T |
6: 42,606,679 (GRCm39) |
M425K |
probably benign |
Het |
| Tdrp |
A |
G |
8: 14,003,845 (GRCm39) |
V164A |
possibly damaging |
Het |
| Tmbim1 |
A |
G |
1: 74,328,568 (GRCm39) |
F298S |
probably damaging |
Het |
| Tmem89 |
A |
G |
9: 108,743,829 (GRCm39) |
|
probably benign |
Het |
| Trpm2 |
G |
T |
10: 77,768,023 (GRCm39) |
C825* |
probably null |
Het |
| Tsc1 |
A |
G |
2: 28,565,201 (GRCm39) |
E421G |
possibly damaging |
Het |
| Usp24 |
T |
C |
4: 106,245,834 (GRCm39) |
I1364T |
probably benign |
Het |
| Vmn1r52 |
G |
A |
6: 90,155,930 (GRCm39) |
G78E |
possibly damaging |
Het |
| Vmn2r73 |
T |
G |
7: 85,506,829 (GRCm39) |
I828L |
probably damaging |
Het |
| Vwa5b1 |
A |
T |
4: 138,338,058 (GRCm39) |
D87E |
probably benign |
Het |
| Zfp1010 |
T |
C |
2: 176,957,223 (GRCm39) |
T92A |
possibly damaging |
Het |
| Zfp451 |
A |
T |
1: 33,844,465 (GRCm39) |
D47E |
probably damaging |
Het |
| Zfp821 |
A |
G |
8: 110,450,841 (GRCm39) |
E278G |
probably damaging |
Het |
| Zfp930 |
A |
T |
8: 69,681,597 (GRCm39) |
T430S |
probably benign |
Het |
| Zfp994 |
G |
T |
17: 22,419,448 (GRCm39) |
Y500* |
probably null |
Het |
| Zmat3 |
A |
T |
3: 32,397,836 (GRCm39) |
I142N |
probably damaging |
Het |
| Zzef1 |
T |
A |
11: 72,792,214 (GRCm39) |
I2266N |
probably damaging |
Het |
|
| Other mutations in Arhgap32 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01020:Arhgap32
|
APN |
9 |
32,168,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01317:Arhgap32
|
APN |
9 |
32,168,260 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL01614:Arhgap32
|
APN |
9 |
32,171,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01791:Arhgap32
|
APN |
9 |
32,158,486 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02318:Arhgap32
|
APN |
9 |
32,170,627 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02542:Arhgap32
|
APN |
9 |
32,166,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Arhgap32
|
APN |
9 |
32,158,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02627:Arhgap32
|
APN |
9 |
32,157,302 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02927:Arhgap32
|
APN |
9 |
32,172,431 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03157:Arhgap32
|
APN |
9 |
32,170,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03286:Arhgap32
|
APN |
9 |
32,170,816 (GRCm39) |
missense |
probably benign |
0.06 |
|
PIT4445001:Arhgap32
|
UTSW |
9 |
32,172,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0004:Arhgap32
|
UTSW |
9 |
32,063,294 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0335:Arhgap32
|
UTSW |
9 |
32,171,056 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0380:Arhgap32
|
UTSW |
9 |
32,157,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0396:Arhgap32
|
UTSW |
9 |
32,156,551 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0494:Arhgap32
|
UTSW |
9 |
32,170,199 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0508:Arhgap32
|
UTSW |
9 |
32,101,364 (GRCm39) |
splice site |
probably benign |
|
|
R0856:Arhgap32
|
UTSW |
9 |
32,171,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0990:Arhgap32
|
UTSW |
9 |
32,166,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Arhgap32
|
UTSW |
9 |
32,166,608 (GRCm39) |
missense |
probably benign |
|
|
R1455:Arhgap32
|
UTSW |
9 |
32,171,381 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1515:Arhgap32
|
UTSW |
9 |
32,027,498 (GRCm39) |
missense |
probably benign |
|
|
R1523:Arhgap32
|
UTSW |
9 |
32,168,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1651:Arhgap32
|
UTSW |
9 |
32,171,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1743:Arhgap32
|
UTSW |
9 |
32,170,727 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1999:Arhgap32
|
UTSW |
9 |
32,027,436 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R2098:Arhgap32
|
UTSW |
9 |
32,171,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2150:Arhgap32
|
UTSW |
9 |
32,027,436 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R2256:Arhgap32
|
UTSW |
9 |
32,158,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2257:Arhgap32
|
UTSW |
9 |
32,158,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2989:Arhgap32
|
UTSW |
9 |
32,150,694 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R3780:Arhgap32
|
UTSW |
9 |
32,063,315 (GRCm39) |
splice site |
probably null |
|
|
R3793:Arhgap32
|
UTSW |
9 |
32,166,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3846:Arhgap32
|
UTSW |
9 |
32,101,320 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4086:Arhgap32
|
UTSW |
9 |
32,158,362 (GRCm39) |
unclassified |
probably benign |
|
|
R4177:Arhgap32
|
UTSW |
9 |
32,158,510 (GRCm39) |
missense |
probably null |
1.00 |
|
R4230:Arhgap32
|
UTSW |
9 |
32,168,770 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4280:Arhgap32
|
UTSW |
9 |
32,171,185 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4504:Arhgap32
|
UTSW |
9 |
32,093,135 (GRCm39) |
splice site |
probably null |
|
|
R4587:Arhgap32
|
UTSW |
9 |
32,172,241 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4612:Arhgap32
|
UTSW |
9 |
32,170,775 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4622:Arhgap32
|
UTSW |
9 |
32,150,644 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4670:Arhgap32
|
UTSW |
9 |
32,081,441 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4784:Arhgap32
|
UTSW |
9 |
32,172,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4784:Arhgap32
|
UTSW |
9 |
32,040,949 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4785:Arhgap32
|
UTSW |
9 |
32,040,949 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4785:Arhgap32
|
UTSW |
9 |
32,172,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5046:Arhgap32
|
UTSW |
9 |
32,168,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5360:Arhgap32
|
UTSW |
9 |
32,170,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5382:Arhgap32
|
UTSW |
9 |
32,063,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5445:Arhgap32
|
UTSW |
9 |
32,159,678 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5637:Arhgap32
|
UTSW |
9 |
32,158,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5659:Arhgap32
|
UTSW |
9 |
32,093,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5801:Arhgap32
|
UTSW |
9 |
32,167,084 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6002:Arhgap32
|
UTSW |
9 |
32,168,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6109:Arhgap32
|
UTSW |
9 |
32,171,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Arhgap32
|
UTSW |
9 |
32,159,784 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6922:Arhgap32
|
UTSW |
9 |
32,063,983 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7009:Arhgap32
|
UTSW |
9 |
32,157,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7137:Arhgap32
|
UTSW |
9 |
32,063,232 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7183:Arhgap32
|
UTSW |
9 |
32,097,679 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7251:Arhgap32
|
UTSW |
9 |
32,119,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7287:Arhgap32
|
UTSW |
9 |
32,063,993 (GRCm39) |
missense |
|
|
|
R7289:Arhgap32
|
UTSW |
9 |
32,168,234 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7289:Arhgap32
|
UTSW |
9 |
32,168,233 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7391:Arhgap32
|
UTSW |
9 |
32,093,235 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7408:Arhgap32
|
UTSW |
9 |
32,157,220 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7566:Arhgap32
|
UTSW |
9 |
32,162,018 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7584:Arhgap32
|
UTSW |
9 |
32,168,263 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7653:Arhgap32
|
UTSW |
9 |
32,168,441 (GRCm39) |
missense |
probably benign |
|
|
R7884:Arhgap32
|
UTSW |
9 |
32,171,810 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8087:Arhgap32
|
UTSW |
9 |
32,168,324 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8109:Arhgap32
|
UTSW |
9 |
32,093,150 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8131:Arhgap32
|
UTSW |
9 |
32,158,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8155:Arhgap32
|
UTSW |
9 |
32,093,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8232:Arhgap32
|
UTSW |
9 |
32,168,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8303:Arhgap32
|
UTSW |
9 |
32,172,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8304:Arhgap32
|
UTSW |
9 |
32,167,233 (GRCm39) |
nonsense |
probably null |
|
|
R8696:Arhgap32
|
UTSW |
9 |
32,159,799 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8832:Arhgap32
|
UTSW |
9 |
32,172,115 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9112:Arhgap32
|
UTSW |
9 |
32,157,309 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9170:Arhgap32
|
UTSW |
9 |
32,162,039 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9279:Arhgap32
|
UTSW |
9 |
32,168,655 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9431:Arhgap32
|
UTSW |
9 |
32,170,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9522:Arhgap32
|
UTSW |
9 |
32,027,450 (GRCm39) |
missense |
probably benign |
|
|
R9526:Arhgap32
|
UTSW |
9 |
32,172,026 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9661:Arhgap32
|
UTSW |
9 |
32,168,531 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0027:Arhgap32
|
UTSW |
9 |
32,161,937 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
X0063:Arhgap32
|
UTSW |
9 |
32,172,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Arhgap32
|
UTSW |
9 |
32,171,976 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAGGTTGCCAGGTGTAGATAC -3'
(R):5'- GGACACTGCAGATAATGAAATGTC -3'
Sequencing Primer
(F):5'- AATAAACCGGTGATGATCTTCCTCC -3'
(R):5'- TGTCATTTAGGAGGAGAATAACGTG -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation