Incidental Mutation 'R4906:Phldb2'
| ID |
378236 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phldb2
|
| Ensembl Gene |
ENSMUSG00000033149 |
| Gene Name |
pleckstrin homology like domain, family B, member 2 |
| Synonyms |
LL5b, C820004H04Rik, LL5beta |
| MMRRC Submission |
042508-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4906 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
45566606-45773961 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 45571758 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Asparagine
at position 473
(K473N)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036355]
[ENSMUST00000076333]
|
| AlphaFold |
Q8K1N2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000036355
AA Change: K1158N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000046496
Gene: ENSMUSG00000033149
AA Change: K1158N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
coiled coil region
|
1027 |
1097 |
N/A |
INTRINSIC |
|
PH
|
1140 |
1244 |
6.45e-17 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000076333
AA Change: K1211N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000075672
Gene: ENSMUSG00000033149
AA Change: K1211N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
901 |
913 |
N/A |
INTRINSIC |
|
coiled coil region
|
1080 |
1150 |
N/A |
INTRINSIC |
|
PH
|
1193 |
1297 |
6.45e-17 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000131003
AA Change: K473N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000119718
Gene: ENSMUSG00000033149
AA Change: K473N
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
55 |
N/A |
INTRINSIC |
|
coiled coil region
|
87 |
163 |
N/A |
INTRINSIC |
|
coiled coil region
|
342 |
412 |
N/A |
INTRINSIC |
|
PH
|
456 |
560 |
6.45e-17 |
SMART |
|
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 98.1%
- 10x: 95.7%
- 20x: 90.5%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5330417H12Rik |
T |
C |
7: 107,223,897 (GRCm39) |
|
probably benign |
Het |
| Ablim2 |
C |
T |
5: 35,959,766 (GRCm39) |
R73C |
possibly damaging |
Het |
| Adgrf2 |
T |
C |
17: 43,022,084 (GRCm39) |
I247V |
probably benign |
Het |
| Adgrv1 |
A |
G |
13: 81,418,857 (GRCm39) |
|
probably null |
Het |
| Ankrd22 |
T |
A |
19: 34,126,752 (GRCm39) |
K26I |
possibly damaging |
Het |
| Arhgap32 |
T |
A |
9: 32,156,552 (GRCm39) |
|
probably null |
Het |
| Armc10 |
A |
G |
5: 21,866,522 (GRCm39) |
Y262C |
probably damaging |
Het |
| Arrb2 |
A |
G |
11: 70,330,725 (GRCm39) |
D374G |
probably benign |
Het |
| Ascc3 |
C |
T |
10: 50,625,227 (GRCm39) |
R1675C |
probably damaging |
Het |
| Atg5 |
T |
C |
10: 44,239,046 (GRCm39) |
*276R |
probably null |
Het |
| Bcl11b |
G |
A |
12: 107,882,968 (GRCm39) |
T377M |
probably damaging |
Het |
| C1s2 |
C |
A |
6: 124,612,073 (GRCm39) |
E104* |
probably null |
Het |
| Carf |
A |
T |
1: 60,180,526 (GRCm39) |
H316L |
probably damaging |
Het |
| Ccdc77 |
A |
T |
6: 120,311,796 (GRCm39) |
I234N |
probably damaging |
Het |
| Cd300c2 |
A |
T |
11: 114,887,826 (GRCm39) |
V192E |
possibly damaging |
Het |
| Cep72 |
G |
A |
13: 74,207,584 (GRCm39) |
R62C |
probably damaging |
Het |
| Clasp1 |
T |
A |
1: 118,436,640 (GRCm39) |
L308* |
probably null |
Het |
| Clec2g |
A |
G |
6: 128,956,411 (GRCm39) |
S25G |
probably benign |
Het |
| Cngb1 |
T |
C |
8: 95,978,601 (GRCm39) |
M1046V |
probably damaging |
Het |
| Cobll1 |
A |
T |
2: 64,928,037 (GRCm39) |
D1095E |
probably benign |
Het |
| Cpeb2 |
A |
G |
5: 43,402,005 (GRCm39) |
H662R |
possibly damaging |
Het |
| Cps1 |
A |
T |
1: 67,178,922 (GRCm39) |
T45S |
probably benign |
Het |
| Cspp1 |
A |
G |
1: 10,152,553 (GRCm39) |
Q368R |
possibly damaging |
Het |
| Dcaf6 |
C |
A |
1: 165,239,032 (GRCm39) |
|
probably null |
Het |
| Dcst1 |
T |
C |
3: 89,257,814 (GRCm39) |
Y652C |
possibly damaging |
Het |
| Elf5 |
T |
G |
2: 103,279,918 (GRCm39) |
Y225* |
probably null |
Het |
| Ermap |
A |
C |
4: 119,046,015 (GRCm39) |
|
probably benign |
Het |
| Fam186b |
A |
T |
15: 99,169,202 (GRCm39) |
V915D |
probably damaging |
Het |
| Fbxo34 |
C |
A |
14: 47,766,911 (GRCm39) |
N90K |
probably benign |
Het |
| Flnc |
A |
G |
6: 29,447,524 (GRCm39) |
E1109G |
probably damaging |
Het |
| Flt1 |
C |
A |
5: 147,620,749 (GRCm39) |
A132S |
probably benign |
Het |
| Gabpb2 |
A |
G |
3: 95,097,947 (GRCm39) |
V242A |
probably benign |
Het |
| Gas2l3 |
CACTCGTCATACT |
CACT |
10: 89,266,820 (GRCm39) |
|
probably benign |
Het |
| Gm21798 |
A |
T |
15: 64,689,732 (GRCm39) |
|
probably benign |
Het |
| Gpr179 |
A |
T |
11: 97,237,487 (GRCm39) |
S345T |
possibly damaging |
Het |
| Gusb |
A |
T |
5: 130,026,959 (GRCm39) |
F377L |
probably damaging |
Het |
| Hnrnpu |
T |
C |
1: 178,156,938 (GRCm39) |
|
probably benign |
Het |
| Htr3b |
C |
T |
9: 48,848,348 (GRCm39) |
|
probably null |
Het |
| Iqub |
A |
T |
6: 24,501,368 (GRCm39) |
V194D |
probably damaging |
Het |
| Itga2b |
A |
G |
11: 102,351,985 (GRCm39) |
V504A |
probably benign |
Het |
| Itga4 |
T |
A |
2: 79,118,592 (GRCm39) |
F430L |
probably damaging |
Het |
| Jcad |
C |
A |
18: 4,673,762 (GRCm39) |
P508H |
probably damaging |
Het |
| Jph1 |
T |
C |
1: 17,161,835 (GRCm39) |
T276A |
probably damaging |
Het |
| Kansl2 |
A |
G |
15: 98,429,771 (GRCm39) |
F87S |
possibly damaging |
Het |
| Kdm1b |
T |
C |
13: 47,216,620 (GRCm39) |
|
probably null |
Het |
| Kif5b |
C |
T |
18: 6,220,930 (GRCm39) |
D393N |
probably benign |
Het |
| Kmt2d |
A |
T |
15: 98,747,420 (GRCm39) |
|
probably benign |
Het |
| Krt75 |
A |
G |
15: 101,478,674 (GRCm39) |
I320T |
probably damaging |
Het |
| Lhfpl7 |
T |
A |
5: 113,386,036 (GRCm39) |
M161K |
probably benign |
Het |
| Lipo5 |
T |
C |
19: 33,443,348 (GRCm39) |
N156S |
unknown |
Het |
| Mblac2 |
A |
C |
13: 81,859,706 (GRCm39) |
Q19P |
probably null |
Het |
| Mdfic2 |
A |
T |
6: 98,215,080 (GRCm39) |
M181K |
probably damaging |
Het |
| Mfsd4b3-ps |
T |
C |
10: 39,824,056 (GRCm39) |
H68R |
probably damaging |
Het |
| Mzb1 |
A |
T |
18: 35,781,006 (GRCm39) |
|
probably null |
Het |
| Nup210l |
T |
A |
3: 90,077,337 (GRCm39) |
I891N |
probably benign |
Het |
| Nwd1 |
G |
A |
8: 73,398,841 (GRCm39) |
R667Q |
probably damaging |
Het |
| Oas1h |
C |
T |
5: 121,005,172 (GRCm39) |
Q207* |
probably null |
Het |
| Or13c7d |
A |
T |
4: 43,770,476 (GRCm39) |
F178L |
possibly damaging |
Het |
| Pcdh15 |
C |
T |
10: 74,340,625 (GRCm39) |
R1120* |
probably null |
Het |
| Pfkl |
A |
G |
10: 77,824,144 (GRCm39) |
L748P |
probably damaging |
Het |
| Rapgef6 |
G |
A |
11: 54,443,662 (GRCm39) |
V82I |
probably damaging |
Het |
| Rfc3 |
A |
T |
5: 151,570,960 (GRCm39) |
L112Q |
probably damaging |
Het |
| Rsph6a |
T |
A |
7: 18,801,997 (GRCm39) |
C349S |
possibly damaging |
Het |
| Sec16a |
A |
T |
2: 26,331,979 (GRCm39) |
|
probably benign |
Het |
| Septin14 |
T |
A |
5: 129,770,030 (GRCm39) |
Y222F |
probably benign |
Het |
| Skor2 |
T |
C |
18: 76,947,990 (GRCm39) |
S571P |
possibly damaging |
Het |
| Slc13a5 |
T |
A |
11: 72,148,244 (GRCm39) |
M264L |
probably damaging |
Het |
| Slc45a3 |
T |
A |
1: 131,909,315 (GRCm39) |
V504E |
probably damaging |
Het |
| Smg1 |
C |
T |
7: 117,751,631 (GRCm39) |
|
probably benign |
Het |
| Smim20 |
A |
G |
5: 53,434,503 (GRCm39) |
N45S |
probably null |
Het |
| Spp2 |
A |
T |
1: 88,339,991 (GRCm39) |
S111C |
probably damaging |
Het |
| Sspo |
A |
G |
6: 48,442,664 (GRCm39) |
|
probably null |
Het |
| Sycp2 |
C |
T |
2: 178,045,450 (GRCm39) |
|
probably null |
Het |
| Tas2r113 |
A |
G |
6: 132,870,521 (GRCm39) |
N183S |
possibly damaging |
Het |
| Tcaf2 |
A |
T |
6: 42,606,679 (GRCm39) |
M425K |
probably benign |
Het |
| Tdrp |
A |
G |
8: 14,003,845 (GRCm39) |
V164A |
possibly damaging |
Het |
| Tmbim1 |
A |
G |
1: 74,328,568 (GRCm39) |
F298S |
probably damaging |
Het |
| Tmem89 |
A |
G |
9: 108,743,829 (GRCm39) |
|
probably benign |
Het |
| Trpm2 |
G |
T |
10: 77,768,023 (GRCm39) |
C825* |
probably null |
Het |
| Tsc1 |
A |
G |
2: 28,565,201 (GRCm39) |
E421G |
possibly damaging |
Het |
| Usp24 |
T |
C |
4: 106,245,834 (GRCm39) |
I1364T |
probably benign |
Het |
| Vmn1r52 |
G |
A |
6: 90,155,930 (GRCm39) |
G78E |
possibly damaging |
Het |
| Vmn2r73 |
T |
G |
7: 85,506,829 (GRCm39) |
I828L |
probably damaging |
Het |
| Vwa5b1 |
A |
T |
4: 138,338,058 (GRCm39) |
D87E |
probably benign |
Het |
| Zfp1010 |
T |
C |
2: 176,957,223 (GRCm39) |
T92A |
possibly damaging |
Het |
| Zfp451 |
A |
T |
1: 33,844,465 (GRCm39) |
D47E |
probably damaging |
Het |
| Zfp821 |
A |
G |
8: 110,450,841 (GRCm39) |
E278G |
probably damaging |
Het |
| Zfp930 |
A |
T |
8: 69,681,597 (GRCm39) |
T430S |
probably benign |
Het |
| Zfp994 |
G |
T |
17: 22,419,448 (GRCm39) |
Y500* |
probably null |
Het |
| Zmat3 |
A |
T |
3: 32,397,836 (GRCm39) |
I142N |
probably damaging |
Het |
| Zzef1 |
T |
A |
11: 72,792,214 (GRCm39) |
I2266N |
probably damaging |
Het |
|
| Other mutations in Phldb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00321:Phldb2
|
APN |
16 |
45,592,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00485:Phldb2
|
APN |
16 |
45,577,551 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL00544:Phldb2
|
APN |
16 |
45,645,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00547:Phldb2
|
APN |
16 |
45,645,898 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00835:Phldb2
|
APN |
16 |
45,571,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00987:Phldb2
|
APN |
16 |
45,583,465 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL01102:Phldb2
|
APN |
16 |
45,645,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01530:Phldb2
|
APN |
16 |
45,623,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Phldb2
|
APN |
16 |
45,594,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01712:Phldb2
|
APN |
16 |
45,571,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01755:Phldb2
|
APN |
16 |
45,645,945 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01823:Phldb2
|
APN |
16 |
45,645,507 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02353:Phldb2
|
APN |
16 |
45,569,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02360:Phldb2
|
APN |
16 |
45,569,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02716:Phldb2
|
APN |
16 |
45,621,953 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0139:Phldb2
|
UTSW |
16 |
45,591,029 (GRCm39) |
splice site |
probably benign |
|
|
R0312:Phldb2
|
UTSW |
16 |
45,609,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0379:Phldb2
|
UTSW |
16 |
45,601,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0535:Phldb2
|
UTSW |
16 |
45,577,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1387:Phldb2
|
UTSW |
16 |
45,646,357 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R1444:Phldb2
|
UTSW |
16 |
45,577,616 (GRCm39) |
splice site |
probably benign |
|
|
R1487:Phldb2
|
UTSW |
16 |
45,609,387 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1501:Phldb2
|
UTSW |
16 |
45,598,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1605:Phldb2
|
UTSW |
16 |
45,591,142 (GRCm39) |
splice site |
probably benign |
|
|
R1716:Phldb2
|
UTSW |
16 |
45,595,413 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1732:Phldb2
|
UTSW |
16 |
45,577,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1779:Phldb2
|
UTSW |
16 |
45,621,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1824:Phldb2
|
UTSW |
16 |
45,646,374 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2001:Phldb2
|
UTSW |
16 |
45,594,558 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2066:Phldb2
|
UTSW |
16 |
45,591,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Phldb2
|
UTSW |
16 |
45,583,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2448:Phldb2
|
UTSW |
16 |
45,645,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2932:Phldb2
|
UTSW |
16 |
45,569,148 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3076:Phldb2
|
UTSW |
16 |
45,645,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3078:Phldb2
|
UTSW |
16 |
45,645,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3779:Phldb2
|
UTSW |
16 |
45,569,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3914:Phldb2
|
UTSW |
16 |
45,577,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4536:Phldb2
|
UTSW |
16 |
45,591,044 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4568:Phldb2
|
UTSW |
16 |
45,598,081 (GRCm39) |
nonsense |
probably null |
|
|
R4798:Phldb2
|
UTSW |
16 |
45,646,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4853:Phldb2
|
UTSW |
16 |
45,623,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4984:Phldb2
|
UTSW |
16 |
45,645,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5078:Phldb2
|
UTSW |
16 |
45,598,105 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5137:Phldb2
|
UTSW |
16 |
45,628,621 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5237:Phldb2
|
UTSW |
16 |
45,568,249 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5410:Phldb2
|
UTSW |
16 |
45,645,975 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5825:Phldb2
|
UTSW |
16 |
45,583,460 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5874:Phldb2
|
UTSW |
16 |
45,621,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5907:Phldb2
|
UTSW |
16 |
45,645,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6332:Phldb2
|
UTSW |
16 |
45,594,609 (GRCm39) |
missense |
probably benign |
|
|
R6354:Phldb2
|
UTSW |
16 |
45,645,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6355:Phldb2
|
UTSW |
16 |
45,645,701 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6383:Phldb2
|
UTSW |
16 |
45,569,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6463:Phldb2
|
UTSW |
16 |
45,595,356 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6513:Phldb2
|
UTSW |
16 |
45,568,240 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6593:Phldb2
|
UTSW |
16 |
45,645,790 (GRCm39) |
nonsense |
probably null |
|
|
R6756:Phldb2
|
UTSW |
16 |
45,628,683 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6810:Phldb2
|
UTSW |
16 |
45,569,088 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6897:Phldb2
|
UTSW |
16 |
45,598,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7010:Phldb2
|
UTSW |
16 |
45,571,868 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7142:Phldb2
|
UTSW |
16 |
45,577,539 (GRCm39) |
nonsense |
probably null |
|
|
R7149:Phldb2
|
UTSW |
16 |
45,571,895 (GRCm39) |
nonsense |
probably null |
|
|
R7249:Phldb2
|
UTSW |
16 |
45,621,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7300:Phldb2
|
UTSW |
16 |
45,645,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7328:Phldb2
|
UTSW |
16 |
45,578,572 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7515:Phldb2
|
UTSW |
16 |
45,594,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7840:Phldb2
|
UTSW |
16 |
45,571,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7988:Phldb2
|
UTSW |
16 |
45,645,934 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8159:Phldb2
|
UTSW |
16 |
45,680,747 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8353:Phldb2
|
UTSW |
16 |
45,645,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8453:Phldb2
|
UTSW |
16 |
45,645,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8969:Phldb2
|
UTSW |
16 |
45,592,496 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9058:Phldb2
|
UTSW |
16 |
45,592,604 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9106:Phldb2
|
UTSW |
16 |
45,680,757 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9278:Phldb2
|
UTSW |
16 |
45,646,308 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9324:Phldb2
|
UTSW |
16 |
45,595,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9563:Phldb2
|
UTSW |
16 |
45,645,247 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9626:Phldb2
|
UTSW |
16 |
45,592,547 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9712:Phldb2
|
UTSW |
16 |
45,595,340 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9718:Phldb2
|
UTSW |
16 |
45,601,756 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
RF008:Phldb2
|
UTSW |
16 |
45,583,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,773,871 (GRCm39) |
unclassified |
probably benign |
|
|
Z1176:Phldb2
|
UTSW |
16 |
45,646,190 (GRCm39) |
missense |
probably benign |
0.04 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,646,189 (GRCm39) |
missense |
probably benign |
0.43 |
|
Z1190:Phldb2
|
UTSW |
16 |
45,645,697 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGCCTACCAAGTTATCATTGCC -3'
(R):5'- ACGGCCATCATCTATGCAC -3'
Sequencing Primer
(F):5'- AGATAGGGTCTCATCACCGTG -3'
(R):5'- CGGCCATCATCTATGCACTATAG -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation