Mutagenetix > Incidental Mutation

Incidental Mutation 'R4908:Matr3'

379247

Institutional Source

Beutler Lab

Gene Symbol

Matr3

Ensembl Gene

ENSMUSG00000037236

Gene Name

matrin 3

Synonyms

D030046F20Rik, 2810017I02Rik, 1110061A14Rik

MMRRC Submission

042510-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.961) question?

Stock #

R4908 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

35695191-35726888 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 35705754 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 226 (D226E)

Ref Sequence

ENSEMBL: ENSMUSP00000140846 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000166793] [ENSMUST00000186292] [ENSMUST00000186614] [ENSMUST00000186796] [ENSMUST00000187389] [ENSMUST00000187513] [ENSMUST00000190029] [ENSMUST00000188275] [ENSMUST00000189039] [ENSMUST00000190653] [ENSMUST00000188767] [ENSMUST00000188359] [ENSMUST00000189163] [ENSMUST00000190458] [ENSMUST00000190121] [ENSMUST00000187793] [ENSMUST00000187543]

AlphaFold

Q8K310

Predicted Effect

probably damaging
Transcript: ENSMUST00000166793
AA Change: D226E

PolyPhen 2 Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000125761
Gene: ENSMUSG00000037236
AA Change: D226E

Domain	Start	End	E-Value	Type
low complexity region	23	32	N/A	INTRINSIC
low complexity region	52	65	N/A	INTRINSIC
low complexity region	69	85	N/A	INTRINSIC
ZnF_U1	288	322	4.47e-6	SMART
ZnF_C2H2	291	315	2.12e1	SMART
low complexity region	351	361	N/A	INTRINSIC
low complexity region	371	386	N/A	INTRINSIC
RRM	399	469	7.74e-3	SMART
RRM	497	567	5.63e-9	SMART
low complexity region	650	675	N/A	INTRINSIC
low complexity region	710	718	N/A	INTRINSIC
ZnF_U1	797	832	1.87e-8	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000186292

SMART Domains

Protein: ENSMUSP00000139437
Gene: ENSMUSG00000037236

Domain	Start	End	E-Value	Type
low complexity region	23	32	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000186295

Predicted Effect

probably benign
Transcript: ENSMUST00000186614
AA Change: D226E

PolyPhen 2 Score 0.026 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000141189
Gene: ENSMUSG00000037236
AA Change: D226E

Domain	Start	End	E-Value	Type
low complexity region	23	32	N/A	INTRINSIC
low complexity region	52	65	N/A	INTRINSIC
low complexity region	69	85	N/A	INTRINSIC
ZnF_U1	288	322	2.6e-8	SMART
ZnF_C2H2	291	315	8.8e-2	SMART
low complexity region	351	361	N/A	INTRINSIC
low complexity region	371	386	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000186796

SMART Domains

Protein: ENSMUSP00000140128
Gene: ENSMUSG00000037236

Domain	Start	End	E-Value	Type
low complexity region	13	23	N/A	INTRINSIC
low complexity region	33	48	N/A	INTRINSIC
RRM	61	131	3.2e-5	SMART
RRM	159	229	2.4e-11	SMART
low complexity region	312	337	N/A	INTRINSIC
low complexity region	372	380	N/A	INTRINSIC
ZnF_U1	459	494	1.1e-10	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000187389
AA Change: D226E

PolyPhen 2 Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000139745
Gene: ENSMUSG00000037236
AA Change: D226E

Domain	Start	End	E-Value	Type
low complexity region	23	32	N/A	INTRINSIC
low complexity region	52	65	N/A	INTRINSIC
low complexity region	69	85	N/A	INTRINSIC
ZnF_U1	288	322	4.47e-6	SMART
ZnF_C2H2	291	315	2.12e1	SMART
low complexity region	351	361	N/A	INTRINSIC
low complexity region	371	386	N/A	INTRINSIC
RRM	399	469	7.74e-3	SMART
RRM	497	567	5.63e-9	SMART
low complexity region	650	675	N/A	INTRINSIC
low complexity region	710	718	N/A	INTRINSIC
ZnF_U1	797	832	1.87e-8	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000187513

SMART Domains

Protein: ENSMUSP00000139875
Gene: ENSMUSG00000099703

Domain	Start	End	E-Value	Type
low complexity region	23	32	N/A	INTRINSIC
low complexity region	52	65	N/A	INTRINSIC
low complexity region	69	85	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000187980

Predicted Effect

probably damaging
Transcript: ENSMUST00000190029
AA Change: D226E

PolyPhen 2 Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000140846
Gene: ENSMUSG00000037236
AA Change: D226E

Domain	Start	End	E-Value	Type
low complexity region	23	32	N/A	INTRINSIC
low complexity region	52	65	N/A	INTRINSIC
low complexity region	69	85	N/A	INTRINSIC
ZnF_U1	288	322	4.47e-6	SMART
ZnF_C2H2	291	315	2.12e1	SMART
low complexity region	351	361	N/A	INTRINSIC
low complexity region	371	386	N/A	INTRINSIC
RRM	399	469	7.74e-3	SMART
RRM	497	567	5.63e-9	SMART
low complexity region	650	675	N/A	INTRINSIC
low complexity region	710	718	N/A	INTRINSIC
ZnF_U1	797	832	1.87e-8	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000193225

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000190570

Predicted Effect

probably benign
Transcript: ENSMUST00000188275

SMART Domains

Protein: ENSMUSP00000140401
Gene: ENSMUSG00000037236

Domain	Start	End	E-Value	Type
low complexity region	63	73	N/A	INTRINSIC
low complexity region	83	98	N/A	INTRINSIC
RRM	111	181	3.2e-5	SMART
RRM	209	279	2.4e-11	SMART
low complexity region	362	387	N/A	INTRINSIC
low complexity region	422	430	N/A	INTRINSIC
ZnF_U1	509	544	1.1e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000189039

SMART Domains

Protein: ENSMUSP00000139525
Gene: ENSMUSG00000037236

Domain	Start	End	E-Value	Type
ZnF_U1	36	70	2.6e-8	SMART
ZnF_C2H2	39	63	8.8e-2	SMART
low complexity region	99	109	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000190653

SMART Domains

Protein: ENSMUSP00000141135
Gene: ENSMUSG00000037236

Domain	Start	End	E-Value	Type
low complexity region	13	23	N/A	INTRINSIC
low complexity region	33	48	N/A	INTRINSIC
RRM	61	131	3.2e-5	SMART
RRM	159	229	2.4e-11	SMART
low complexity region	312	337	N/A	INTRINSIC
low complexity region	372	380	N/A	INTRINSIC
ZnF_U1	459	494	1.1e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000188767

SMART Domains

Protein: ENSMUSP00000141027
Gene: ENSMUSG00000037236

Domain	Start	End	E-Value	Type
low complexity region	13	23	N/A	INTRINSIC
low complexity region	33	48	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000188359

SMART Domains

Protein: ENSMUSP00000140148
Gene: ENSMUSG00000037236

Domain	Start	End	E-Value	Type
low complexity region	23	32	N/A	INTRINSIC
low complexity region	52	65	N/A	INTRINSIC
low complexity region	69	85	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000189163

Predicted Effect

probably benign
Transcript: ENSMUST00000190458

SMART Domains

Protein: ENSMUSP00000139922
Gene: ENSMUSG00000099703

Domain	Start	End	E-Value	Type
low complexity region	23	32	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000190121

SMART Domains

Protein: ENSMUSP00000140853
Gene: ENSMUSG00000037236

Domain	Start	End	E-Value	Type
low complexity region	13	23	N/A	INTRINSIC
low complexity region	33	48	N/A	INTRINSIC
RRM	61	131	3.2e-5	SMART
RRM	159	229	2.4e-11	SMART
low complexity region	312	337	N/A	INTRINSIC
low complexity region	372	380	N/A	INTRINSIC
ZnF_U1	459	494	1.1e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000187793

SMART Domains

Protein: ENSMUSP00000140047
Gene: ENSMUSG00000099703

Domain	Start	End	E-Value	Type
low complexity region	13	23	N/A	INTRINSIC
SCOP:d1lvk_2	42	78	4e-3	SMART
PDB:1X4D\|A	52	102	4e-30	PDB
Blast:RRM	61	102	1e-22	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000187543

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.2%
20x: 92.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013]
PHENOTYPE: Mice homozygous for a gene-trapped allele are early embryonic lethal. Heterozygotes show congenital heart defects including abnormal heart apex morphology, subaortic ventricular septal defects, double-outlet right ventricle, bicuspid aortic valve, aorta coarctation, and patent ductus arteriosus. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 99 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110059G10Rik	T	A	9: 122,778,008 (GRCm39)	I79L	probably benign	Het
Ablim2	C	T	5: 35,959,766 (GRCm39)	R73C	possibly damaging	Het
Acaa1a	G	A	9: 119,177,772 (GRCm39)	S218N	probably benign	Het
Acsm5	A	T	7: 119,137,314 (GRCm39)	I377F	probably damaging	Het
Ahnak2	T	C	12: 112,741,706 (GRCm39)	T789A	probably benign	Het
Ak9	A	T	10: 41,296,678 (GRCm39)	T1475S	unknown	Het
AU040320	A	T	4: 126,747,081 (GRCm39)	N1028Y	probably damaging	Het
Bahcc1	T	A	11: 120,178,580 (GRCm39)	S2380T	probably benign	Het
Cadps	A	G	14: 12,536,386 (GRCm38)	Y525H	probably damaging	Het
Casp8ap2	A	G	4: 32,639,905 (GRCm39)	T320A	possibly damaging	Het
Ccdc138	A	G	10: 58,380,817 (GRCm39)	N483D	possibly damaging	Het
Ccdc39	G	A	3: 33,893,242 (GRCm39)		probably null	Het
Cd300c2	T	C	11: 114,887,772 (GRCm39)	N210S	probably damaging	Het
Cd84	A	G	1: 171,700,432 (GRCm39)	D183G	probably damaging	Het
Cep95	C	T	11: 106,702,172 (GRCm39)	P390S	probably damaging	Het
Chd9	A	T	8: 91,741,877 (GRCm39)	H1622L	possibly damaging	Het
Cilp	C	A	9: 65,185,302 (GRCm39)	Q466K	probably benign	Het
Cinp	T	A	12: 110,850,487 (GRCm39)	T5S	probably damaging	Het
Clec4a2	T	C	6: 123,119,462 (GRCm39)	L238S	probably damaging	Het
Cntrob	T	C	11: 69,211,732 (GRCm39)	Y164C	probably damaging	Het
Col6a3	A	G	1: 90,735,246 (GRCm39)	L1408P	probably damaging	Het
Cul3	G	A	1: 80,258,632 (GRCm39)	S468L	possibly damaging	Het
Dnah11	T	A	12: 118,090,618 (GRCm39)	D1081V	probably benign	Het
Dnah2	C	A	11: 69,411,973 (GRCm39)	V263L	probably benign	Het
Efna3	C	G	3: 89,222,805 (GRCm39)	R185P	probably damaging	Het
F5	A	T	1: 164,039,389 (GRCm39)	I2000F	probably damaging	Het
Fancm	G	A	12: 65,141,645 (GRCm39)	G422E	probably benign	Het
Gcnt2	A	T	13: 41,014,210 (GRCm39)	D127V	probably damaging	Het
Gm21798	G	T	15: 64,689,618 (GRCm39)		probably benign	Het
Gramd1a	A	C	7: 30,838,292 (GRCm39)	S320R	probably benign	Het
Grn	T	C	11: 102,327,344 (GRCm39)		probably benign	Het
Helq	A	T	5: 100,910,507 (GRCm39)		probably null	Het
Herc2	A	G	7: 55,827,660 (GRCm39)	I2914V	probably benign	Het
Hnrnph1	T	C	11: 50,269,237 (GRCm39)	V27A	probably damaging	Het
Hs1bp3	G	T	12: 8,374,007 (GRCm39)	G182C	probably damaging	Het
Idnk	C	T	13: 58,311,267 (GRCm39)	P78L	probably benign	Het
Il10ra	T	C	9: 45,166,919 (GRCm39)	D544G	probably benign	Het
Inpp5e	T	C	2: 26,290,918 (GRCm39)	D383G	probably damaging	Het
Jak1	A	T	4: 101,036,911 (GRCm39)	V243D	probably damaging	Het
Kcnma1	A	T	14: 23,359,220 (GRCm39)	S1036T	probably damaging	Het
Kif26a	G	A	12: 112,123,776 (GRCm39)	C127Y	probably damaging	Het
Kif2c	T	C	4: 117,023,608 (GRCm39)	E368G	probably damaging	Het
Lasp1	T	A	11: 97,724,530 (GRCm39)		probably null	Het
Lcor	T	A	19: 41,572,601 (GRCm39)	V452D	probably benign	Het
Lrrtm1	C	G	6: 77,221,661 (GRCm39)	H373D	probably benign	Het
Mmp17	G	A	5: 129,682,730 (GRCm39)	W456*	probably null	Het
Mpp4	T	C	1: 59,164,748 (GRCm39)	E463G	probably damaging	Het
Myh6	A	C	14: 55,194,419 (GRCm39)	F737V	probably damaging	Het
Nars2	T	A	7: 96,672,948 (GRCm39)	D271E	probably benign	Het
Nav2	A	G	7: 49,254,258 (GRCm39)	E2352G	probably damaging	Het
Nckap1	A	G	2: 80,353,718 (GRCm39)		probably null	Het
Nckap5	A	T	1: 125,955,324 (GRCm39)	S477R	probably damaging	Het
Nek11	T	G	9: 105,175,488 (GRCm39)	I319L	probably benign	Het
Neto2	A	G	8: 86,396,393 (GRCm39)	I84T	probably damaging	Het
Nlrp9a	A	T	7: 26,250,369 (GRCm39)	I45F	probably damaging	Het
Numa1	G	A	7: 101,662,012 (GRCm39)	R548H	probably damaging	Het
Or10a5	A	C	7: 106,635,364 (GRCm39)	M1L	probably benign	Het
Or14c39	A	C	7: 86,344,395 (GRCm39)	I244L	probably benign	Het
Or2ag1b	A	T	7: 106,288,740 (GRCm39)	L66H	probably damaging	Het
Or4c10	A	T	2: 89,760,923 (GRCm39)	M257L	probably benign	Het
Or4c100	T	A	2: 88,356,254 (GRCm39)	I109N	probably damaging	Het
Or4k36	T	A	2: 111,146,574 (GRCm39)	F250Y	probably benign	Het
Or7g25	A	G	9: 19,160,149 (GRCm39)	V182A	probably benign	Het
Or9m1	A	T	2: 87,733,533 (GRCm39)	N162K	probably damaging	Het
Pcdhb16	T	A	18: 37,612,894 (GRCm39)		probably null	Het
Pdcd10	T	C	3: 75,448,553 (GRCm39)	T4A	probably damaging	Het
Pgc	A	T	17: 48,039,819 (GRCm39)	Y71F	probably damaging	Het
Phlpp1	G	A	1: 106,317,481 (GRCm39)	G1234E	probably damaging	Het
Prr27	T	C	5: 87,990,888 (GRCm39)	F167L	probably benign	Het
Prrc2b	T	A	2: 32,116,330 (GRCm39)	S1421T	possibly damaging	Het
Pxmp2	A	G	5: 110,431,518 (GRCm39)	V75A	probably benign	Het
Pygl	A	T	12: 70,243,807 (GRCm39)	M545K	probably null	Het
Ranbp9	A	G	13: 43,574,733 (GRCm39)	Y412H	possibly damaging	Het
Rcc1	A	G	4: 132,065,064 (GRCm39)	V140A	probably damaging	Het
Reln	A	G	5: 22,184,718 (GRCm39)	V1599A	probably benign	Het
Rhebl1	A	T	15: 98,776,903 (GRCm39)	D122E	probably damaging	Het
Rock2	C	T	12: 17,009,492 (GRCm39)	L676F	probably benign	Het
Scn9a	A	T	2: 66,357,087 (GRCm39)	D1062E	probably benign	Het
Sec63	T	C	10: 42,681,186 (GRCm39)	I390T	probably damaging	Het
Slc10a6	T	C	5: 103,754,493 (GRCm39)	E346G	probably benign	Het
Slc12a3	G	A	8: 95,075,216 (GRCm39)	V737M	possibly damaging	Het
Slc12a8	T	C	16: 33,426,629 (GRCm39)		probably null	Het
Slc25a38	T	A	9: 119,949,354 (GRCm39)	I102N	probably damaging	Het
Spg7	T	A	8: 123,807,394 (GRCm39)	V390E	probably damaging	Het
Tbc1d20	T	C	2: 152,144,228 (GRCm39)	V75A	probably benign	Het
Tesk1	T	A	4: 43,445,555 (GRCm39)	C243*	probably null	Het
Ttk	T	A	9: 83,725,739 (GRCm39)	N220K	possibly damaging	Het
Ttll5	A	G	12: 85,965,948 (GRCm39)	E651G	probably benign	Het
Tubd1	T	C	11: 86,457,879 (GRCm39)	Y426H	probably damaging	Het
Uba6	T	C	5: 86,288,293 (GRCm39)		silent	Het
Ube2ql1	G	A	13: 69,852,289 (GRCm39)	R263W	probably damaging	Het
Vmn2r117	C	T	17: 23,678,812 (GRCm39)	G804D	probably damaging	Het
Vmn2r25	C	T	6: 123,805,406 (GRCm39)	E484K	probably benign	Het
Vmn2r4	T	A	3: 64,296,476 (GRCm39)	I770F	possibly damaging	Het
Vmn2r82	G	A	10: 79,214,589 (GRCm39)	V191M	probably benign	Het
Zbtb45	C	T	7: 12,742,037 (GRCm39)	V74M	probably damaging	Het
Zfp366	T	C	13: 99,370,609 (GRCm39)	V443A	possibly damaging	Het
Zfyve1	A	T	12: 83,598,345 (GRCm39)	C628S	probably damaging	Het
Zfyve26	A	T	12: 79,296,469 (GRCm39)		probably null	Het

Other mutations in Matr3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01396:Matr3	APN	18	35,721,442 (GRCm39)	missense	probably damaging	1.00
IGL03083:Matr3	APN	18	35,705,471 (GRCm39)	missense	probably damaging	0.96
IGL03117:Matr3	APN	18	35,705,710 (GRCm39)	missense	probably damaging	1.00
IGL03163:Matr3	APN	18	35,705,644 (GRCm39)	missense	probably damaging	0.99
IGL03381:Matr3	APN	18	35,712,078 (GRCm39)	splice site	probably benign
R0456:Matr3	UTSW	18	35,705,917 (GRCm39)	missense	probably damaging	1.00
R1136:Matr3	UTSW	18	35,705,948 (GRCm39)	missense	probably damaging	1.00
R1459:Matr3	UTSW	18	35,717,709 (GRCm39)	missense	probably benign	0.28
R1850:Matr3	UTSW	18	35,715,110 (GRCm39)	missense	probably damaging	1.00
R1929:Matr3	UTSW	18	35,721,378 (GRCm39)	splice site	probably benign
R2185:Matr3	UTSW	18	35,714,278 (GRCm39)	missense	probably damaging	1.00
R2366:Matr3	UTSW	18	35,721,448 (GRCm39)	missense	probably damaging	1.00
R2870:Matr3	UTSW	18	35,705,349 (GRCm39)	missense	probably benign	0.25
R2870:Matr3	UTSW	18	35,705,349 (GRCm39)	missense	probably benign	0.25
R2871:Matr3	UTSW	18	35,705,349 (GRCm39)	missense	probably benign	0.25
R2871:Matr3	UTSW	18	35,705,349 (GRCm39)	missense	probably benign	0.25
R2872:Matr3	UTSW	18	35,705,349 (GRCm39)	missense	probably benign	0.25
R2872:Matr3	UTSW	18	35,705,349 (GRCm39)	missense	probably benign	0.25
R2873:Matr3	UTSW	18	35,705,349 (GRCm39)	missense	probably benign	0.25
R3908:Matr3	UTSW	18	35,705,894 (GRCm39)	missense	probably damaging	1.00
R4400:Matr3	UTSW	18	35,716,969 (GRCm39)	missense	possibly damaging	0.80
R4417:Matr3	UTSW	18	35,705,171 (GRCm39)	missense	probably damaging	1.00
R4860:Matr3	UTSW	18	35,714,693 (GRCm39)	missense	probably damaging	1.00
R4860:Matr3	UTSW	18	35,714,693 (GRCm39)	missense	probably damaging	1.00
R4881:Matr3	UTSW	18	35,705,428 (GRCm39)	missense	probably damaging	1.00
R5084:Matr3	UTSW	18	35,715,135 (GRCm39)	missense	probably damaging	0.99
R5660:Matr3	UTSW	18	35,705,147 (GRCm39)	missense	probably damaging	0.99
R5709:Matr3	UTSW	18	35,715,015 (GRCm39)	missense	probably damaging	1.00
R5779:Matr3	UTSW	18	35,717,575 (GRCm39)	missense	possibly damaging	0.81
R5876:Matr3	UTSW	18	35,720,791 (GRCm39)	missense	probably benign
R6392:Matr3	UTSW	18	35,717,894 (GRCm39)	missense	probably benign	0.07
R7062:Matr3	UTSW	18	35,712,072 (GRCm39)	critical splice donor site	probably null
R7156:Matr3	UTSW	18	35,705,974 (GRCm39)	missense	probably damaging	0.98
R7228:Matr3	UTSW	18	35,695,537 (GRCm39)	missense	unknown
R7389:Matr3	UTSW	18	35,717,638 (GRCm39)	missense	probably benign
R8940:Matr3	UTSW	18	35,705,640 (GRCm39)	missense	probably damaging	0.98
R9071:Matr3	UTSW	18	35,705,803 (GRCm39)	missense	possibly damaging	0.94
R9159:Matr3	UTSW	18	35,712,355 (GRCm39)	missense	possibly damaging	0.71
R9205:Matr3	UTSW	18	35,720,774 (GRCm39)	missense	probably benign	0.08
R9587:Matr3	UTSW	18	35,717,876 (GRCm39)	missense	probably null	0.13

Predicted Primers

PCR Primer
(F):5'- AGGCCCTACATTGAGTTATGG -3'
(R):5'- CGGTAAGAGTCCATGGAAGTC -3'

Sequencing Primer
(F):5'- CCCTACATTGAGTTATGGTAGAGATG -3'
(R):5'- CTTCAATATTGCTACTTGGAGGAGC -3'

Posted On

2016-04-15