Mutagenetix > Incidental Mutation

Incidental Mutation 'R4911:Fsip2'

379482

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

042513-MU

Accession Numbers

Genbank: XM_913669; MGI: 2664111

Essential gene?

Probably non essential (E-score: 0.174) question?

Stock #

R4911 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

82943634-83008937 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 82981493 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Threonine at position 2719 (S2719T)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000132967
AA Change: S233T

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249
AA Change: S233T

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000143764
AA Change: S2719T

PolyPhen 2 Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: S2719T

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Meta Mutation Damage Score

0.0992

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 95.5%
20x: 89.7%

Validation Efficiency

97% (149/153)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 132 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2010111I01Rik	A	T	13: 63,170,939 (GRCm38)		probably null	Het
4430402I18Rik	G	A	19: 28,897,503 (GRCm38)		probably benign	Het
Aacs	A	G	5: 125,506,160 (GRCm38)	D260G	possibly damaging	Het
Aadacl4	T	A	4: 144,613,792 (GRCm38)	L29H	probably damaging	Het
Abca7	T	C	10: 80,012,188 (GRCm38)		probably null	Het
Adgre1	G	A	17: 57,447,832 (GRCm38)	M643I	possibly damaging	Het
Adgrl2	A	T	3: 148,890,463 (GRCm38)	M79K	probably damaging	Het
Ankrd55	T	A	13: 112,323,039 (GRCm38)		probably null	Het
Arhgap21	A	G	2: 20,858,989 (GRCm38)	I1257T	probably damaging	Het
Arhgap26	T	A	18: 38,993,637 (GRCm38)		probably benign	Het
Arhgap39	A	G	15: 76,737,805 (GRCm38)	S199P	probably damaging	Het
Arhgef5	A	G	6: 43,272,828 (GRCm38)	D171G	probably benign	Het
Atp7a	T	C	X: 106,120,374 (GRCm38)	V1305A	probably damaging	Het
B3gnt3	T	A	8: 71,692,934 (GRCm38)	R263S	probably benign	Het
B9d1	A	C	11: 61,507,671 (GRCm38)	D59A	probably benign	Het
Bag2	A	T	1: 33,748,276 (GRCm38)	I55N	probably benign	Het
Bank1	T	C	3: 136,284,243 (GRCm38)	I29V	probably benign	Het
Bbs2	A	T	8: 94,089,115 (GRCm38)	D174E	probably damaging	Het
Bmp8b	T	C	4: 123,115,237 (GRCm38)	W203R	probably damaging	Het
Cacnb2	A	T	2: 14,981,340 (GRCm38)	E359D	possibly damaging	Het
Camp	T	A	9: 109,847,583 (GRCm38)		probably null	Het
Casp4	C	T	9: 5,328,580 (GRCm38)		probably benign	Het
Ccdc110	A	T	8: 45,942,907 (GRCm38)	T612S	probably benign	Het
Cd209b	T	A	8: 3,926,640 (GRCm38)		probably null	Het
Cemip	T	C	7: 83,983,253 (GRCm38)	D367G	probably damaging	Het
Cers5	T	A	15: 99,747,079 (GRCm38)	N131I	probably damaging	Het
Chd5	T	G	4: 152,360,672 (GRCm38)	V370G	probably damaging	Het
Cipc	C	A	12: 86,952,757 (GRCm38)	Q20K	probably benign	Het
Cnr2	T	A	4: 135,917,201 (GRCm38)	F197I	possibly damaging	Het
Col7a1	G	A	9: 108,975,219 (GRCm38)	G2233S	unknown	Het
Dcdc2b	T	A	4: 129,611,267 (GRCm38)	I125F	possibly damaging	Het
Ddi2	A	G	4: 141,684,402 (GRCm38)	S400P	probably benign	Het
Ddx31	C	A	2: 28,904,684 (GRCm38)	T664K	probably benign	Het
Dhx30	C	A	9: 110,100,924 (GRCm38)	G35C	probably damaging	Het
Dmxl2	G	A	9: 54,411,653 (GRCm38)	T1576I	probably damaging	Het
Dnah1	T	C	14: 31,295,323 (GRCm38)	Y1510C	probably damaging	Het
Dnah2	C	T	11: 69,499,104 (GRCm38)		probably null	Het
Dock10	C	A	1: 80,606,236 (GRCm38)	G163C	probably damaging	Het
Edar	T	C	10: 58,621,324 (GRCm38)	N144S	probably benign	Het
Elavl2	T	A	4: 91,308,678 (GRCm38)	E54D	possibly damaging	Het
Enam	T	G	5: 88,502,314 (GRCm38)	S561A	probably benign	Het
Ercc5	C	A	1: 44,166,871 (GRCm38)	H315N	possibly damaging	Het
Esp31	A	G	17: 38,644,661 (GRCm38)	E65G	possibly damaging	Het
Faap100	T	C	11: 120,372,113 (GRCm38)	I806M	probably benign	Het
Fam159a	T	C	4: 108,377,461 (GRCm38)	T70A	probably benign	Het
Fbxw21	T	C	9: 109,145,663 (GRCm38)	Y263C	probably damaging	Het
Fv1	T	C	4: 147,869,418 (GRCm38)	V147A	probably benign	Het
Gal	T	C	19: 3,411,590 (GRCm38)	E65G	probably benign	Het
Galnt6	T	C	15: 100,716,178 (GRCm38)	T81A	probably benign	Het
Gcc2	A	G	10: 58,270,439 (GRCm38)	E399G	probably damaging	Het
Gfi1b	A	T	2: 28,610,102 (GRCm38)	C306S	probably damaging	Het
Gm10654	T	A	8: 70,931,852 (GRCm38)		noncoding transcript	Het
Gm20388	A	G	8: 123,080,604 (GRCm38)		probably benign	Het
Gm4788	T	G	1: 139,774,563 (GRCm38)	D61A	probably damaging	Het
Gm4953	T	A	1: 159,168,359 (GRCm38)		noncoding transcript	Het
Gorasp2	T	C	2: 70,688,339 (GRCm38)		probably benign	Het
Gse1	T	C	8: 120,568,466 (GRCm38)		probably benign	Het
H2-D1	A	G	17: 35,265,997 (GRCm38)	E278G	probably damaging	Het
Herc2	T	C	7: 56,227,892 (GRCm38)	L4569P	probably damaging	Het
Hgs	T	A	11: 120,477,202 (GRCm38)	S246T	probably damaging	Het
Hs2st1	T	C	3: 144,465,082 (GRCm38)	T110A	probably benign	Het
Hydin	A	G	8: 110,595,438 (GRCm38)	Y4574C	probably benign	Het
Ighv1-23	C	A	12: 114,764,752 (GRCm38)	V17F	possibly damaging	Het
Ighv8-14	A	T	12: 115,808,565 (GRCm38)		noncoding transcript	Het
Igsf21	C	T	4: 140,034,623 (GRCm38)	R248H	probably benign	Het
Il23r	T	C	6: 67,423,561 (GRCm38)	N595S	probably benign	Het
Il5ra	G	T	6: 106,715,668 (GRCm38)	P372Q	probably damaging	Het
Iltifb	T	C	10: 118,294,989 (GRCm38)	M1V	probably null	Het
Inppl1	A	G	7: 101,832,309 (GRCm38)	V222A	possibly damaging	Het
Ints10	T	C	8: 68,827,312 (GRCm38)	V697A	probably damaging	Het
Isg15	T	A	4: 156,199,760 (GRCm38)	T104S	probably benign	Het
Kif11	A	G	19: 37,417,937 (GRCm38)	T983A	probably benign	Het
Kif3b	A	T	2: 153,317,292 (GRCm38)	K338*	probably null	Het
Kpna2	T	A	11: 106,990,719 (GRCm38)	I362F	probably damaging	Het
Lama2	G	A	10: 27,138,927 (GRCm38)	T1595M	probably damaging	Het
Lrrc36	A	G	8: 105,426,935 (GRCm38)	T126A	probably benign	Het
Lrrk1	T	A	7: 66,295,454 (GRCm38)	D604V	probably damaging	Het
Map7d1	T	C	4: 126,236,691 (GRCm38)	K409E	probably damaging	Het
Mast2	T	C	4: 116,353,057 (GRCm38)	T110A	probably benign	Het
Micall2	G	A	5: 139,716,825 (GRCm38)	T221M	probably damaging	Het
Morc2b	T	A	17: 33,137,377 (GRCm38)	N474Y	probably damaging	Het
Myo1e	T	A	9: 70,343,096 (GRCm38)	M528K	probably benign	Het
Nlrp1c-ps	G	T	11: 71,260,369 (GRCm38)		noncoding transcript	Het
Nostrin	T	C	2: 69,161,142 (GRCm38)	S160P	possibly damaging	Het
Nup133	T	C	8: 123,927,131 (GRCm38)	R530G	possibly damaging	Het
Olfr452	T	A	6: 42,790,204 (GRCm38)	L55H	probably damaging	Het
Olfr488	T	C	7: 108,256,037 (GRCm38)	I34V	possibly damaging	Het
Olfr894	A	G	9: 38,219,096 (GRCm38)	E91G	probably damaging	Het
Pabpc4l	A	T	3: 46,446,162 (GRCm38)	M349K	possibly damaging	Het
Pah	G	A	10: 87,570,267 (GRCm38)	G256S	probably benign	Het
Park2	G	T	17: 10,840,472 (GRCm38)		probably benign	Het
Pigk	T	C	3: 152,740,204 (GRCm38)	S151P	probably damaging	Het
Plcd4	A	C	1: 74,564,413 (GRCm38)	T658P	possibly damaging	Het
Pld4	A	T	12: 112,764,517 (GRCm38)	S178C	probably benign	Het
Polr1a	G	A	6: 71,909,229 (GRCm38)	E23K	possibly damaging	Het
Pomt1	T	C	2: 32,241,679 (GRCm38)	S127P	probably damaging	Het
Pon2	A	G	6: 5,269,029 (GRCm38)	V215A	possibly damaging	Het
Ppp3cb	A	T	14: 20,509,440 (GRCm38)	M416K	probably damaging	Het
Prdm1	A	T	10: 44,442,052 (GRCm38)	N273K	possibly damaging	Het
Prg4	T	A	1: 150,455,823 (GRCm38)		probably benign	Het
Ptch1	G	A	13: 63,523,052 (GRCm38)	T888M	probably damaging	Het
Pusl1	T	G	4: 155,891,442 (GRCm38)		probably benign	Het
Rapgef6	A	T	11: 54,622,317 (GRCm38)	E122D	probably damaging	Het
Rif1	C	T	2: 52,110,518 (GRCm38)	T1328I	probably damaging	Het
Rngtt	T	G	4: 33,500,292 (GRCm38)		probably null	Het
Runx2	G	A	17: 44,814,192 (GRCm38)	P80L	probably damaging	Het
Samd1	A	G	8: 83,998,989 (GRCm38)		probably benign	Het
Scamp5	A	T	9: 57,451,452 (GRCm38)	F14I	probably damaging	Het
Shank3	C	T	15: 89,504,344 (GRCm38)	R380C	probably damaging	Het
Slc1a4	C	A	11: 20,332,166 (GRCm38)	A103S	probably damaging	Het
Slc39a14	A	G	14: 70,309,922 (GRCm38)	V325A	probably benign	Het
Slc5a9	C	A	4: 111,891,744 (GRCm38)		probably null	Het
Spta1	T	A	1: 174,185,647 (GRCm38)	S375T	probably damaging	Het
Sval1	A	G	6: 41,955,444 (GRCm38)	N76S	probably benign	Het
Synpo	C	T	18: 60,629,864 (GRCm38)		probably benign	Het
Sytl5	C	T	X: 9,915,602 (GRCm38)	P181L	possibly damaging	Het
Tacc1	A	G	8: 25,182,606 (GRCm38)	M111T	possibly damaging	Het
Tec	T	C	5: 72,756,351 (GRCm38)	D613G	probably benign	Het
Tecpr2	C	T	12: 110,931,487 (GRCm38)	T391I	possibly damaging	Het
Thop1	G	A	10: 81,073,291 (GRCm38)	G52D	probably damaging	Het
Tmco5	T	A	2: 116,892,208 (GRCm38)	V270D	possibly damaging	Het
Ttn	C	T	2: 76,726,629 (GRCm38)	E28265K	possibly damaging	Het
Tuft1	T	C	3: 94,635,443 (GRCm38)	D72G	probably damaging	Het
Tyrp1	C	T	4: 80,850,907 (GRCm38)		probably benign	Het
Usp9y	T	C	Y: 1,308,041 (GRCm38)	D2265G	probably damaging	Het
Vmn2r104	G	A	17: 20,030,026 (GRCm38)	A661V	probably benign	Het
Vwa5a	A	T	9: 38,737,972 (GRCm38)	N672I	probably benign	Het
Wdr95	A	T	5: 149,611,692 (GRCm38)	K772*	probably null	Het
Ybx1	T	C	4: 119,282,813 (GRCm38)	T106A	probably benign	Het
Ypel3	T	C	7: 126,777,789 (GRCm38)	S14P	probably benign	Het
Zfp518a	T	A	19: 40,915,528 (GRCm38)	S1300R	probably benign	Het
Zscan5b	A	T	7: 6,239,190 (GRCm38)	*469Y	probably null	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,990,386 (GRCm38)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,991,313 (GRCm38)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,999,819 (GRCm38)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,992,982 (GRCm38)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,977,519 (GRCm38)	missense	probably benign
IGL01554:Fsip2	APN	2	82,977,278 (GRCm38)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,991,086 (GRCm38)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,978,347 (GRCm38)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,982,639 (GRCm38)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,984,929 (GRCm38)	missense	probably benign
IGL01918:Fsip2	APN	2	82,992,138 (GRCm38)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,994,005 (GRCm38)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,993,867 (GRCm38)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,991,860 (GRCm38)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,978,721 (GRCm38)	missense	probably benign
IGL02155:Fsip2	APN	2	82,998,352 (GRCm38)	missense	probably benign
IGL02219:Fsip2	APN	2	82,977,830 (GRCm38)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,982,772 (GRCm38)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,978,793 (GRCm38)	missense	probably benign
IGL02478:Fsip2	APN	2	82,984,392 (GRCm38)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,978,855 (GRCm38)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,992,003 (GRCm38)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,949,492 (GRCm38)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,993,063 (GRCm38)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,998,318 (GRCm38)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,982,157 (GRCm38)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,951,026 (GRCm38)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,993,495 (GRCm38)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,992,357 (GRCm38)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,983,054 (GRCm38)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,990,624 (GRCm38)	intron	probably benign
IGL03076:Fsip2	APN	2	82,982,138 (GRCm38)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,978,076 (GRCm38)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,977,393 (GRCm38)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,990,470 (GRCm38)	missense	probably benign
bubblegum	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
Dao	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
engulf	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
envelope	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
gladius	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
glove	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
Katana	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
scarf	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
Sock	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
swaddle	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
wrap	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
Wrapper	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,988,412 (GRCm38)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,984,365 (GRCm38)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,984,362 (GRCm38)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,990,852 (GRCm38)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,999,857 (GRCm38)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,976,608 (GRCm38)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,984,925 (GRCm38)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,991,121 (GRCm38)	missense	probably benign
R0149:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,980,807 (GRCm38)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,985,177 (GRCm38)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,985,896 (GRCm38)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,983,333 (GRCm38)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,984,564 (GRCm38)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,991,075 (GRCm38)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,977,785 (GRCm38)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,946,952 (GRCm38)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,993,795 (GRCm38)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,977,533 (GRCm38)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,944,140 (GRCm38)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,988,958 (GRCm38)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,976,897 (GRCm38)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,986,169 (GRCm38)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,991,359 (GRCm38)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,982,339 (GRCm38)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,986,273 (GRCm38)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,985,484 (GRCm38)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,998,031 (GRCm38)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,989,436 (GRCm38)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,988,461 (GRCm38)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,975,034 (GRCm38)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,991,500 (GRCm38)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,975,226 (GRCm38)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,975,017 (GRCm38)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,981,011 (GRCm38)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,989,763 (GRCm38)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,989,408 (GRCm38)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,989,745 (GRCm38)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,998,063 (GRCm38)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,987,195 (GRCm38)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,979,811 (GRCm38)	missense	probably benign
R1520:Fsip2	UTSW	2	82,980,714 (GRCm38)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,981,587 (GRCm38)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,986,282 (GRCm38)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,978,517 (GRCm38)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,986,345 (GRCm38)	missense	probably benign
R1700:Fsip2	UTSW	2	82,991,737 (GRCm38)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,974,945 (GRCm38)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,989,912 (GRCm38)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,987,711 (GRCm38)	missense	possibly damaging	0.71
R1760:Fsip2	UTSW	2	82,984,896 (GRCm38)	missense	probably benign	0.07
R1760:Fsip2	UTSW	2	82,999,841 (GRCm38)	missense	possibly damaging	0.85
R1789:Fsip2	UTSW	2	82,977,562 (GRCm38)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,984,589 (GRCm38)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,993,257 (GRCm38)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,980,783 (GRCm38)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,986,733 (GRCm38)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,980,558 (GRCm38)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,991,550 (GRCm38)	missense	probably benign
R1965:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,979,831 (GRCm38)	missense	probably benign
R1988:Fsip2	UTSW	2	82,976,517 (GRCm38)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,989,444 (GRCm38)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R2037:Fsip2	UTSW	2	82,978,512 (GRCm38)	missense	probably damaging	0.99
R2070:Fsip2	UTSW	2	82,976,355 (GRCm38)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	83,008,815 (GRCm38)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,988,579 (GRCm38)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,990,271 (GRCm38)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,977,479 (GRCm38)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,962,751 (GRCm38)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,975,093 (GRCm38)	missense	probably benign
R2344:Fsip2	UTSW	2	82,989,913 (GRCm38)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,976,249 (GRCm38)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,980,720 (GRCm38)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,985,341 (GRCm38)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,979,610 (GRCm38)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,951,657 (GRCm38)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,978,167 (GRCm38)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,990,431 (GRCm38)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,979,045 (GRCm38)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,991,524 (GRCm38)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,986,510 (GRCm38)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,992,010 (GRCm38)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,986,727 (GRCm38)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,984,909 (GRCm38)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,988,967 (GRCm38)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,978,217 (GRCm38)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,982,714 (GRCm38)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,950,946 (GRCm38)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,989,606 (GRCm38)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,986,415 (GRCm38)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,958,662 (GRCm38)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,983,518 (GRCm38)	missense	probably benign
R4042:Fsip2	UTSW	2	82,983,552 (GRCm38)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,982,901 (GRCm38)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,987,069 (GRCm38)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,977,857 (GRCm38)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,991,206 (GRCm38)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4458:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,951,665 (GRCm38)	missense	probably benign
R4549:Fsip2	UTSW	2	82,989,628 (GRCm38)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,984,953 (GRCm38)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,986,166 (GRCm38)	missense	possibly damaging	0.71
R4583:Fsip2	UTSW	2	82,978,673 (GRCm38)	missense	probably benign	0.33
R4618:Fsip2	UTSW	2	82,987,759 (GRCm38)	missense	probably benign
R4700:Fsip2	UTSW	2	82,987,029 (GRCm38)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,974,859 (GRCm38)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,975,353 (GRCm38)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,989,285 (GRCm38)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,982,108 (GRCm38)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,987,700 (GRCm38)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,988,442 (GRCm38)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,990,171 (GRCm38)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,985,471 (GRCm38)	missense	probably benign	0.26
R4840:Fsip2	UTSW	2	82,949,395 (GRCm38)	missense	probably benign	0.01
R4865:Fsip2	UTSW	2	82,990,951 (GRCm38)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,974,858 (GRCm38)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,988,094 (GRCm38)	missense	probably benign	0.02
R4918:Fsip2	UTSW	2	82,993,770 (GRCm38)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,985,040 (GRCm38)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,946,932 (GRCm38)	missense	probably damaging	0.97
R4950:Fsip2	UTSW	2	82,977,414 (GRCm38)	missense	probably benign	0.03
R4959:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,985,878 (GRCm38)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,979,429 (GRCm38)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,989,133 (GRCm38)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,988,492 (GRCm38)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,991,116 (GRCm38)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,991,985 (GRCm38)	missense	probably benign
R5119:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,981,424 (GRCm38)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,978,572 (GRCm38)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,982,994 (GRCm38)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,993,161 (GRCm38)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,978,581 (GRCm38)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,988,145 (GRCm38)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,989,841 (GRCm38)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,975,398 (GRCm38)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,990,918 (GRCm38)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,982,228 (GRCm38)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,979,886 (GRCm38)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,985,310 (GRCm38)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,985,198 (GRCm38)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,950,912 (GRCm38)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,950,908 (GRCm38)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,962,746 (GRCm38)	missense	probably benign
R5568:Fsip2	UTSW	2	82,986,564 (GRCm38)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,998,128 (GRCm38)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,988,095 (GRCm38)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,987,494 (GRCm38)	nonsense	probably null
R5712:Fsip2	UTSW	2	83,008,848 (GRCm38)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,977,916 (GRCm38)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,984,740 (GRCm38)	missense	probably benign
R5881:Fsip2	UTSW	2	82,984,441 (GRCm38)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,992,609 (GRCm38)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,988,508 (GRCm38)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,986,748 (GRCm38)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,977,491 (GRCm38)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,963,313 (GRCm38)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,990,468 (GRCm38)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,987,939 (GRCm38)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,992,127 (GRCm38)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,985,673 (GRCm38)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,979,433 (GRCm38)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,991,044 (GRCm38)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,993,768 (GRCm38)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,987,945 (GRCm38)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,987,257 (GRCm38)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,980,727 (GRCm38)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,982,454 (GRCm38)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,989,883 (GRCm38)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,980,441 (GRCm38)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,988,898 (GRCm38)	missense	probably benign	0.16
R6349:Fsip2	UTSW	2	82,993,072 (GRCm38)	missense	probably benign	0.05
R6351:Fsip2	UTSW	2	82,992,684 (GRCm38)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,983,492 (GRCm38)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,982,313 (GRCm38)	missense	probably benign
R6621:Fsip2	UTSW	2	82,989,814 (GRCm38)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,983,227 (GRCm38)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,967,817 (GRCm38)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,979,534 (GRCm38)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,986,432 (GRCm38)	missense	probably benign
R6790:Fsip2	UTSW	2	82,990,939 (GRCm38)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,980,959 (GRCm38)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,985,200 (GRCm38)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,983,625 (GRCm38)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R6945:Fsip2	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
R6950:Fsip2	UTSW	2	82,985,988 (GRCm38)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,978,717 (GRCm38)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,948,286 (GRCm38)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,976,954 (GRCm38)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,986,925 (GRCm38)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,990,635 (GRCm38)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,990,891 (GRCm38)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,980,734 (GRCm38)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,983,152 (GRCm38)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,987,624 (GRCm38)	missense	probably benign
R7126:Fsip2	UTSW	2	82,983,141 (GRCm38)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,982,741 (GRCm38)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,981,197 (GRCm38)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,986,227 (GRCm38)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,993,237 (GRCm38)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,989,068 (GRCm38)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,983,671 (GRCm38)	missense	probably benign
R7228:Fsip2	UTSW	2	82,992,307 (GRCm38)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,982,140 (GRCm38)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,993,263 (GRCm38)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,979,081 (GRCm38)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,982,130 (GRCm38)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,980,519 (GRCm38)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,989,691 (GRCm38)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,983,118 (GRCm38)	missense	probably benign
R7343:Fsip2	UTSW	2	82,979,367 (GRCm38)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,988,796 (GRCm38)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,990,319 (GRCm38)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,985,257 (GRCm38)	missense	possibly damaging	0.53
R7426:Fsip2	UTSW	2	82,980,097 (GRCm38)	missense	probably damaging	0.98
R7450:Fsip2	UTSW	2	82,951,680 (GRCm38)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,988,550 (GRCm38)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,984,852 (GRCm38)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,993,993 (GRCm38)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,989,017 (GRCm38)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,975,241 (GRCm38)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,986,912 (GRCm38)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,981,805 (GRCm38)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,990,111 (GRCm38)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,980,908 (GRCm38)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,988,379 (GRCm38)	missense	probably benign
R7811:Fsip2	UTSW	2	82,998,453 (GRCm38)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,976,700 (GRCm38)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,977,824 (GRCm38)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,951,021 (GRCm38)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,985,776 (GRCm38)	missense	possibly damaging	0.51
R8009:Fsip2	UTSW	2	82,988,449 (GRCm38)	missense	possibly damaging	0.85
R8031:Fsip2	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
R8034:Fsip2	UTSW	2	82,989,355 (GRCm38)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,985,978 (GRCm38)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,958,673 (GRCm38)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,992,952 (GRCm38)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,975,797 (GRCm38)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,987,677 (GRCm38)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,984,744 (GRCm38)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,976,607 (GRCm38)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,990,464 (GRCm38)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,978,143 (GRCm38)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,981,002 (GRCm38)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,988,380 (GRCm38)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,990,755 (GRCm38)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,987,854 (GRCm38)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,991,895 (GRCm38)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8419:Fsip2	UTSW	2	82,978,619 (GRCm38)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,981,566 (GRCm38)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,977,086 (GRCm38)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8459:Fsip2	UTSW	2	82,979,678 (GRCm38)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,979,940 (GRCm38)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,946,992 (GRCm38)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,991,527 (GRCm38)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,984,902 (GRCm38)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,981,109 (GRCm38)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,985,478 (GRCm38)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,983,109 (GRCm38)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,991,262 (GRCm38)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,990,438 (GRCm38)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,979,180 (GRCm38)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,977,337 (GRCm38)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,986,640 (GRCm38)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,980,594 (GRCm38)	missense	probably benign
R8926:Fsip2	UTSW	2	82,993,583 (GRCm38)	missense	possibly damaging	0.84
R8991:Fsip2	UTSW	2	82,985,026 (GRCm38)	missense	probably benign	0.33
R9014:Fsip2	UTSW	2	82,976,554 (GRCm38)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,986,731 (GRCm38)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,998,201 (GRCm38)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,975,836 (GRCm38)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,976,957 (GRCm38)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,985,759 (GRCm38)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,982,826 (GRCm38)	missense	probably benign
R9149:Fsip2	UTSW	2	82,982,030 (GRCm38)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,985,230 (GRCm38)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,987,500 (GRCm38)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,990,081 (GRCm38)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,992,718 (GRCm38)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,985,614 (GRCm38)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,977,318 (GRCm38)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,988,260 (GRCm38)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,988,403 (GRCm38)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,980,695 (GRCm38)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,992,412 (GRCm38)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,989,449 (GRCm38)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,975,563 (GRCm38)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,986,358 (GRCm38)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,975,788 (GRCm38)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,986,941 (GRCm38)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,962,718 (GRCm38)	missense	probably benign
R9523:Fsip2	UTSW	2	82,977,628 (GRCm38)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,967,829 (GRCm38)	missense	probably benign
R9636:Fsip2	UTSW	2	82,990,219 (GRCm38)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,991,640 (GRCm38)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,988,928 (GRCm38)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,975,882 (GRCm38)	missense	probably benign
R9705:Fsip2	UTSW	2	82,993,290 (GRCm38)	missense	probably benign
R9739:Fsip2	UTSW	2	82,993,552 (GRCm38)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,987,897 (GRCm38)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,991,650 (GRCm38)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,979,881 (GRCm38)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,991,521 (GRCm38)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,992,532 (GRCm38)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,977,840 (GRCm38)	missense	probably benign
RF028:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,982,507 (GRCm38)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,951,020 (GRCm38)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,954,946 (GRCm38)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,976,778 (GRCm38)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,987,463 (GRCm38)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,988,634 (GRCm38)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,987,653 (GRCm38)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,975,448 (GRCm38)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,989,665 (GRCm38)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,984,524 (GRCm38)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,946,960 (GRCm38)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,987,203 (GRCm38)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- TGAAGGGAGCTATGATGACCTG -3'
(R):5'- CGTGTTAAACATGGCTCTGTG -3'

Sequencing Primer
(F):5'- AGGGAGCTATGATGACCTGTATCTTC -3'
(R):5'- AAACATGGCTCTGTGTTGTGCC -3'

Posted On

2016-04-15