Incidental Mutation 'R4913:Ubr2'
| ID |
379754 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ubr2
|
| Ensembl Gene |
ENSMUSG00000023977 |
| Gene Name |
ubiquitin protein ligase E3 component n-recognin 2 |
| Synonyms |
ENSMUSG00000043296, E130209G04Rik, 9930021A08Rik |
| MMRRC Submission |
042515-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.872)
|
| Stock # |
R4913 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
47239221-47321482 bp(-) (GRCm39) |
| Type of Mutation |
splice site (5 bp from exon) |
| DNA Base Change (assembly) |
C to A
at 47270385 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000108963
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000113335]
[ENSMUST00000113337]
[ENSMUST00000225599]
|
| AlphaFold |
Q6WKZ8 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000113335
|
| SMART Domains |
Protein: ENSMUSP00000108961
Gene: ENSMUSG00000023977
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_UBR1
|
97 |
167 |
3.14e-32 |
SMART |
|
Pfam:ClpS
|
221 |
302 |
2.4e-23 |
PFAM |
|
low complexity region
|
635 |
646 |
N/A |
INTRINSIC |
|
low complexity region
|
749 |
760 |
N/A |
INTRINSIC |
|
low complexity region
|
872 |
886 |
N/A |
INTRINSIC |
|
coiled coil region
|
1019 |
1046 |
N/A |
INTRINSIC |
|
RING
|
1108 |
1213 |
7.66e-1 |
SMART |
|
low complexity region
|
1221 |
1235 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000113337
|
| SMART Domains |
Protein: ENSMUSP00000108963
Gene: ENSMUSG00000023977
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_UBR1
|
97 |
167 |
3.14e-32 |
SMART |
|
Pfam:ClpS
|
222 |
301 |
6.2e-26 |
PFAM |
|
low complexity region
|
635 |
646 |
N/A |
INTRINSIC |
|
low complexity region
|
749 |
760 |
N/A |
INTRINSIC |
|
low complexity region
|
872 |
886 |
N/A |
INTRINSIC |
|
coiled coil region
|
1019 |
1046 |
N/A |
INTRINSIC |
|
RING
|
1108 |
1213 |
7.66e-1 |
SMART |
|
low complexity region
|
1221 |
1235 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000224759
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000225599
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.0%
- 20x: 91.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
PHENOTYPE: On a mixed genetic background, female homozygotes for a targeted null mutation exhibit embryonic lethality, while males are viable, but sterile due to postnatal testicular degeneration. On an inbred background, both genders die in utero. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl4fm1 |
T |
A |
4: 144,255,381 (GRCm39) |
M267K |
possibly damaging |
Het |
| Acsm5 |
T |
C |
7: 119,133,566 (GRCm39) |
S244P |
probably damaging |
Het |
| Actr6 |
A |
G |
10: 89,550,808 (GRCm39) |
F329L |
probably benign |
Het |
| Actrt3 |
A |
G |
3: 30,652,588 (GRCm39) |
S169P |
probably benign |
Het |
| Agtpbp1 |
C |
A |
13: 59,647,886 (GRCm39) |
G645C |
probably damaging |
Het |
| AI661453 |
C |
T |
17: 47,779,480 (GRCm39) |
R1069* |
probably null |
Het |
| Akr1c6 |
T |
C |
13: 4,504,524 (GRCm39) |
I303T |
probably benign |
Het |
| Arnt |
A |
G |
3: 95,397,965 (GRCm39) |
R588G |
probably damaging |
Het |
| Atf1 |
A |
G |
15: 100,149,979 (GRCm39) |
|
probably null |
Het |
| Casp12 |
T |
C |
9: 5,358,726 (GRCm39) |
V318A |
probably damaging |
Het |
| Cblb |
C |
T |
16: 51,986,392 (GRCm39) |
P545L |
possibly damaging |
Het |
| Cc2d2a |
A |
T |
5: 43,896,665 (GRCm39) |
I1521F |
probably benign |
Het |
| Ccn2 |
T |
C |
10: 24,473,225 (GRCm39) |
C255R |
probably damaging |
Het |
| Ccnb1ip1 |
T |
A |
14: 51,029,601 (GRCm39) |
K154* |
probably null |
Het |
| Cd300a |
A |
T |
11: 114,784,198 (GRCm39) |
K69* |
probably null |
Het |
| Cdin1 |
A |
G |
2: 115,500,568 (GRCm39) |
|
probably null |
Het |
| Clec10a |
A |
G |
11: 70,060,851 (GRCm39) |
Y78C |
probably damaging |
Het |
| Cnot1 |
T |
C |
8: 96,489,695 (GRCm39) |
I503V |
possibly damaging |
Het |
| Cpa2 |
A |
G |
6: 30,554,292 (GRCm39) |
H304R |
probably damaging |
Het |
| Crb2 |
A |
T |
2: 37,680,257 (GRCm39) |
H395L |
probably benign |
Het |
| Dnah8 |
T |
A |
17: 31,038,113 (GRCm39) |
N4257K |
probably damaging |
Het |
| Dnase2a |
G |
A |
8: 85,635,477 (GRCm39) |
D25N |
probably damaging |
Het |
| Drd1 |
T |
C |
13: 54,207,186 (GRCm39) |
T343A |
probably benign |
Het |
| Emid1 |
G |
A |
11: 5,082,012 (GRCm39) |
T161I |
probably benign |
Het |
| Epn2 |
A |
G |
11: 61,425,402 (GRCm39) |
|
probably null |
Het |
| Esp36 |
A |
T |
17: 38,728,055 (GRCm39) |
N75K |
possibly damaging |
Het |
| Faf1 |
A |
G |
4: 109,792,746 (GRCm39) |
S573G |
possibly damaging |
Het |
| Fam149a |
T |
G |
8: 45,806,920 (GRCm39) |
S231R |
probably damaging |
Het |
| Fam78a |
T |
C |
2: 31,959,774 (GRCm39) |
E112G |
probably damaging |
Het |
| Fgf18 |
T |
C |
11: 33,084,316 (GRCm39) |
D46G |
probably benign |
Het |
| Fggy |
G |
A |
4: 95,585,313 (GRCm39) |
|
probably null |
Het |
| Foxb1 |
T |
C |
9: 69,666,859 (GRCm39) |
M224V |
probably benign |
Het |
| Gpr75 |
T |
C |
11: 30,841,808 (GRCm39) |
C238R |
possibly damaging |
Het |
| Gsdmc3 |
A |
G |
15: 63,730,122 (GRCm39) |
*481R |
probably null |
Het |
| H2az2 |
C |
A |
11: 6,383,750 (GRCm39) |
A57S |
probably damaging |
Het |
| Hsd17b11 |
T |
C |
5: 104,140,748 (GRCm39) |
I250V |
probably benign |
Het |
| Hus1 |
C |
A |
11: 8,946,856 (GRCm39) |
L280F |
probably benign |
Het |
| Ide |
A |
T |
19: 37,306,469 (GRCm39) |
H101Q |
unknown |
Het |
| Ido1 |
T |
C |
8: 25,074,533 (GRCm39) |
D279G |
probably benign |
Het |
| Inpp5b |
T |
C |
4: 124,674,214 (GRCm39) |
V307A |
probably benign |
Het |
| Ipo5 |
G |
A |
14: 121,172,498 (GRCm39) |
V519I |
probably damaging |
Het |
| Krba1 |
T |
C |
6: 48,383,891 (GRCm39) |
V239A |
probably benign |
Het |
| Lmod3 |
A |
G |
6: 97,224,125 (GRCm39) |
|
probably null |
Het |
| Macf1 |
T |
C |
4: 123,393,682 (GRCm39) |
D836G |
probably damaging |
Het |
| Malt1 |
G |
T |
18: 65,609,351 (GRCm39) |
C774F |
probably damaging |
Het |
| Map2k4 |
C |
A |
11: 65,600,758 (GRCm39) |
D58Y |
probably damaging |
Het |
| Mc2r |
T |
C |
18: 68,540,411 (GRCm39) |
N294S |
probably benign |
Het |
| Mybpc1 |
A |
G |
10: 88,389,116 (GRCm39) |
|
probably null |
Het |
| Mybpc3 |
A |
G |
2: 90,956,609 (GRCm39) |
E637G |
possibly damaging |
Het |
| Narf |
A |
G |
11: 121,135,469 (GRCm39) |
Q107R |
probably damaging |
Het |
| Nlrp3 |
G |
A |
11: 59,440,064 (GRCm39) |
G547D |
probably benign |
Het |
| Nucb2 |
G |
T |
7: 116,123,540 (GRCm39) |
G51* |
probably null |
Het |
| Or10al5 |
T |
A |
17: 38,063,315 (GRCm39) |
V190D |
possibly damaging |
Het |
| Otog |
C |
A |
7: 45,913,526 (GRCm39) |
D786E |
probably benign |
Het |
| Otogl |
T |
C |
10: 107,712,716 (GRCm39) |
T543A |
probably damaging |
Het |
| Pgap6 |
T |
C |
17: 26,339,513 (GRCm39) |
F584L |
probably damaging |
Het |
| Phf20l1 |
A |
G |
15: 66,476,704 (GRCm39) |
N266S |
probably benign |
Het |
| Pink1 |
G |
T |
4: 138,042,866 (GRCm39) |
S446* |
probably null |
Het |
| Pkp4 |
T |
G |
2: 59,135,794 (GRCm39) |
H186Q |
probably damaging |
Het |
| Prl3b1 |
T |
C |
13: 27,433,460 (GRCm39) |
V205A |
probably damaging |
Het |
| Prss32 |
T |
C |
17: 24,078,157 (GRCm39) |
V281A |
probably damaging |
Het |
| Psd3 |
C |
T |
8: 68,573,821 (GRCm39) |
C120Y |
probably damaging |
Het |
| Ptcra |
A |
G |
17: 47,069,574 (GRCm39) |
L99P |
probably damaging |
Het |
| Rab3gap2 |
C |
T |
1: 184,995,026 (GRCm39) |
T855I |
probably benign |
Het |
| Rabgap1l |
T |
C |
1: 160,066,111 (GRCm39) |
E199G |
probably damaging |
Het |
| Rbm44 |
T |
A |
1: 91,083,216 (GRCm39) |
C580S |
probably damaging |
Het |
| Resf1 |
C |
G |
6: 149,230,887 (GRCm39) |
S1311C |
probably damaging |
Het |
| Rhoq |
T |
C |
17: 87,302,493 (GRCm39) |
V143A |
probably benign |
Het |
| Sacs |
T |
A |
14: 61,451,246 (GRCm39) |
Y4431N |
probably benign |
Het |
| Sec24b |
A |
T |
3: 129,796,028 (GRCm39) |
S367T |
probably benign |
Het |
| Sema4c |
G |
A |
1: 36,589,266 (GRCm39) |
S620F |
probably benign |
Het |
| Slc12a1 |
G |
A |
2: 125,070,670 (GRCm39) |
G1054E |
probably damaging |
Het |
| Slc16a3 |
A |
G |
11: 120,848,794 (GRCm39) |
R417G |
probably benign |
Het |
| Slc22a29 |
A |
T |
19: 8,195,722 (GRCm39) |
S106T |
probably benign |
Het |
| Slc41a2 |
T |
C |
10: 83,149,284 (GRCm39) |
T220A |
probably damaging |
Het |
| Tap1 |
T |
C |
17: 34,412,468 (GRCm39) |
F474L |
possibly damaging |
Het |
| Tas2r106 |
G |
T |
6: 131,655,422 (GRCm39) |
A143D |
probably benign |
Het |
| Tbx6 |
A |
T |
7: 126,383,707 (GRCm39) |
|
probably null |
Het |
| Tfap2a |
T |
A |
13: 40,870,706 (GRCm39) |
N402I |
probably damaging |
Het |
| Tle3 |
T |
A |
9: 61,281,275 (GRCm39) |
V22E |
probably damaging |
Het |
| Trip4 |
T |
C |
9: 65,765,639 (GRCm39) |
I353M |
probably damaging |
Het |
| Ugdh |
A |
G |
5: 65,580,791 (GRCm39) |
|
probably null |
Het |
| Uhrf1 |
T |
C |
17: 56,622,478 (GRCm39) |
V431A |
probably damaging |
Het |
| Usp5 |
C |
G |
6: 124,799,593 (GRCm39) |
K318N |
possibly damaging |
Het |
| Zfp820 |
T |
C |
17: 22,038,200 (GRCm39) |
K376R |
probably benign |
Het |
|
| Other mutations in Ubr2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00324:Ubr2
|
APN |
17 |
47,296,986 (GRCm39) |
splice site |
probably benign |
|
|
IGL00332:Ubr2
|
APN |
17 |
47,301,916 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00518:Ubr2
|
APN |
17 |
47,303,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00693:Ubr2
|
APN |
17 |
47,283,907 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00785:Ubr2
|
APN |
17 |
47,255,791 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL01144:Ubr2
|
APN |
17 |
47,268,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01459:Ubr2
|
APN |
17 |
47,241,435 (GRCm39) |
splice site |
probably benign |
|
|
IGL01637:Ubr2
|
APN |
17 |
47,267,580 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01710:Ubr2
|
APN |
17 |
47,254,335 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01726:Ubr2
|
APN |
17 |
47,303,907 (GRCm39) |
splice site |
probably benign |
|
|
IGL01925:Ubr2
|
APN |
17 |
47,265,875 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01960:Ubr2
|
APN |
17 |
47,284,893 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL02170:Ubr2
|
APN |
17 |
47,278,123 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02308:Ubr2
|
APN |
17 |
47,245,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02387:Ubr2
|
APN |
17 |
47,274,076 (GRCm39) |
missense |
probably benign |
|
|
IGL02696:Ubr2
|
APN |
17 |
47,274,691 (GRCm39) |
missense |
probably benign |
|
|
IGL02726:Ubr2
|
APN |
17 |
47,283,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02750:Ubr2
|
APN |
17 |
47,280,208 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02934:Ubr2
|
APN |
17 |
47,268,266 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL02959:Ubr2
|
APN |
17 |
47,286,877 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03018:Ubr2
|
APN |
17 |
47,264,972 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL03343:Ubr2
|
APN |
17 |
47,262,844 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4280001:Ubr2
|
UTSW |
17 |
47,255,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0044:Ubr2
|
UTSW |
17 |
47,303,911 (GRCm39) |
splice site |
probably benign |
|
|
R0044:Ubr2
|
UTSW |
17 |
47,303,911 (GRCm39) |
splice site |
probably benign |
|
|
R0446:Ubr2
|
UTSW |
17 |
47,294,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0513:Ubr2
|
UTSW |
17 |
47,297,705 (GRCm39) |
nonsense |
probably null |
|
|
R0565:Ubr2
|
UTSW |
17 |
47,266,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0600:Ubr2
|
UTSW |
17 |
47,278,174 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0690:Ubr2
|
UTSW |
17 |
47,249,579 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0710:Ubr2
|
UTSW |
17 |
47,249,607 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0761:Ubr2
|
UTSW |
17 |
47,294,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0798:Ubr2
|
UTSW |
17 |
47,280,102 (GRCm39) |
splice site |
probably benign |
|
|
R0862:Ubr2
|
UTSW |
17 |
47,278,009 (GRCm39) |
nonsense |
probably null |
|
|
R0947:Ubr2
|
UTSW |
17 |
47,252,038 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0972:Ubr2
|
UTSW |
17 |
47,245,187 (GRCm39) |
splice site |
probably null |
|
|
R1500:Ubr2
|
UTSW |
17 |
47,297,615 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1514:Ubr2
|
UTSW |
17 |
47,311,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1533:Ubr2
|
UTSW |
17 |
47,278,173 (GRCm39) |
nonsense |
probably null |
|
|
R1554:Ubr2
|
UTSW |
17 |
47,283,877 (GRCm39) |
missense |
probably benign |
|
|
R1575:Ubr2
|
UTSW |
17 |
47,243,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1602:Ubr2
|
UTSW |
17 |
47,251,987 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1941:Ubr2
|
UTSW |
17 |
47,284,952 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1966:Ubr2
|
UTSW |
17 |
47,265,845 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2041:Ubr2
|
UTSW |
17 |
47,296,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2067:Ubr2
|
UTSW |
17 |
47,274,071 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2111:Ubr2
|
UTSW |
17 |
47,274,071 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2189:Ubr2
|
UTSW |
17 |
47,254,290 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2219:Ubr2
|
UTSW |
17 |
47,296,968 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2307:Ubr2
|
UTSW |
17 |
47,277,141 (GRCm39) |
nonsense |
probably null |
|
|
R3426:Ubr2
|
UTSW |
17 |
47,279,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3428:Ubr2
|
UTSW |
17 |
47,279,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3608:Ubr2
|
UTSW |
17 |
47,255,449 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4080:Ubr2
|
UTSW |
17 |
47,299,648 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4330:Ubr2
|
UTSW |
17 |
47,278,204 (GRCm39) |
missense |
probably null |
1.00 |
|
R4383:Ubr2
|
UTSW |
17 |
47,250,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4460:Ubr2
|
UTSW |
17 |
47,255,971 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4794:Ubr2
|
UTSW |
17 |
47,241,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Ubr2
|
UTSW |
17 |
47,296,922 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5092:Ubr2
|
UTSW |
17 |
47,280,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5209:Ubr2
|
UTSW |
17 |
47,279,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5226:Ubr2
|
UTSW |
17 |
47,294,196 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5250:Ubr2
|
UTSW |
17 |
47,241,368 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5437:Ubr2
|
UTSW |
17 |
47,274,623 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5607:Ubr2
|
UTSW |
17 |
47,245,126 (GRCm39) |
nonsense |
probably null |
|
|
R5848:Ubr2
|
UTSW |
17 |
47,267,581 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6089:Ubr2
|
UTSW |
17 |
47,293,218 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6382:Ubr2
|
UTSW |
17 |
47,268,241 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6552:Ubr2
|
UTSW |
17 |
47,277,194 (GRCm39) |
splice site |
probably null |
|
|
R6630:Ubr2
|
UTSW |
17 |
47,262,910 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R6892:Ubr2
|
UTSW |
17 |
47,245,034 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6936:Ubr2
|
UTSW |
17 |
47,283,957 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7039:Ubr2
|
UTSW |
17 |
47,321,139 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7050:Ubr2
|
UTSW |
17 |
47,272,528 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7078:Ubr2
|
UTSW |
17 |
47,266,779 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R7126:Ubr2
|
UTSW |
17 |
47,284,982 (GRCm39) |
splice site |
probably null |
|
|
R7219:Ubr2
|
UTSW |
17 |
47,246,360 (GRCm39) |
nonsense |
probably null |
|
|
R7262:Ubr2
|
UTSW |
17 |
47,311,665 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7352:Ubr2
|
UTSW |
17 |
47,241,352 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7366:Ubr2
|
UTSW |
17 |
47,266,771 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7449:Ubr2
|
UTSW |
17 |
47,275,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7496:Ubr2
|
UTSW |
17 |
47,301,917 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7759:Ubr2
|
UTSW |
17 |
47,296,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7869:Ubr2
|
UTSW |
17 |
47,301,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7916:Ubr2
|
UTSW |
17 |
47,279,308 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8236:Ubr2
|
UTSW |
17 |
47,262,835 (GRCm39) |
missense |
probably benign |
|
|
R8376:Ubr2
|
UTSW |
17 |
47,253,721 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9026:Ubr2
|
UTSW |
17 |
47,245,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9216:Ubr2
|
UTSW |
17 |
47,292,285 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9339:Ubr2
|
UTSW |
17 |
47,284,865 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9558:Ubr2
|
UTSW |
17 |
47,262,843 (GRCm39) |
missense |
probably benign |
|
|
R9606:Ubr2
|
UTSW |
17 |
47,245,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9644:Ubr2
|
UTSW |
17 |
47,266,706 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9731:Ubr2
|
UTSW |
17 |
47,274,071 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0027:Ubr2
|
UTSW |
17 |
47,311,555 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0061:Ubr2
|
UTSW |
17 |
47,281,037 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
Z1177:Ubr2
|
UTSW |
17 |
47,311,692 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1177:Ubr2
|
UTSW |
17 |
47,270,435 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Ubr2
|
UTSW |
17 |
47,321,069 (GRCm39) |
missense |
probably benign |
0.33 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCCGGTGATAACTGCCATC -3'
(R):5'- CAGGATTGGCTTTTCTCATGTTTAC -3'
Sequencing Primer
(F):5'- GGTGATAACTGCCATCCACATG -3'
(R):5'- GGCTTTTCTCATGTTTACTCTCTGG -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation