Incidental Mutation 'R4916:Dnah7c'
| ID |
380018 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnah7c
|
| Ensembl Gene |
ENSMUSG00000101337 |
| Gene Name |
dynein, axonemal, heavy chain 7C |
| Synonyms |
Dnahc7c |
| MMRRC Submission |
042518-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.371)
|
| Stock # |
R4916 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
46464752-46846636 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46634168 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 1049
(L1049P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140430
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000189749]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000189749
AA Change: L1049P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000140430
Gene: ENSMUSG00000101337
AA Change: L1049P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
714 |
746 |
N/A |
INTRINSIC |
|
Pfam:DHC_N2
|
754 |
1167 |
2.2e-138 |
PFAM |
|
AAA
|
1320 |
1459 |
4e-3 |
SMART |
|
Blast:AAA
|
1601 |
1829 |
4e-87 |
BLAST |
|
AAA
|
1968 |
2116 |
8.7e-4 |
SMART |
|
Pfam:AAA_8
|
2303 |
2574 |
6.2e-73 |
PFAM |
|
Pfam:MT
|
2586 |
2935 |
5.4e-52 |
PFAM |
|
Pfam:AAA_9
|
2953 |
3183 |
7.4e-63 |
PFAM |
|
Pfam:Dynein_heavy
|
3312 |
4021 |
1.3e-250 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 95.9%
- 20x: 91.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 106 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930595D18Rik |
G |
A |
12: 111,141,369 (GRCm39) |
Q19* |
probably null |
Het |
| 6030468B19Rik |
T |
A |
11: 117,697,092 (GRCm39) |
C230* |
probably null |
Het |
| Adcy10 |
A |
G |
1: 165,345,815 (GRCm39) |
E288G |
probably damaging |
Het |
| Adnp |
T |
A |
2: 168,029,537 (GRCm39) |
T51S |
possibly damaging |
Het |
| Agap3 |
C |
A |
5: 24,683,011 (GRCm39) |
A464D |
probably damaging |
Het |
| Ago4 |
A |
C |
4: 126,400,635 (GRCm39) |
C693G |
probably damaging |
Het |
| Ahi1 |
A |
G |
10: 20,860,303 (GRCm39) |
R675G |
probably damaging |
Het |
| Amigo1 |
T |
A |
3: 108,094,981 (GRCm39) |
L160Q |
probably damaging |
Het |
| Ankrd35 |
T |
C |
3: 96,591,438 (GRCm39) |
S575P |
probably benign |
Het |
| Ano3 |
T |
A |
2: 110,601,365 (GRCm39) |
T298S |
possibly damaging |
Het |
| Ap2b1 |
T |
G |
11: 83,281,532 (GRCm39) |
F813V |
probably damaging |
Het |
| Aplnr |
T |
G |
2: 84,967,261 (GRCm39) |
F95L |
probably damaging |
Het |
| Apobec2 |
T |
C |
17: 48,730,153 (GRCm39) |
E171G |
probably benign |
Het |
| Ascc1 |
A |
G |
10: 59,840,684 (GRCm39) |
N15S |
probably benign |
Het |
| AY358078 |
T |
A |
14: 52,040,108 (GRCm39) |
Y73N |
unknown |
Het |
| B3gnt8 |
C |
A |
7: 25,328,308 (GRCm39) |
P246Q |
probably damaging |
Het |
| C2cd2l |
T |
C |
9: 44,227,857 (GRCm39) |
Q250R |
probably damaging |
Het |
| Camk2d |
T |
C |
3: 126,577,624 (GRCm39) |
Y180H |
probably damaging |
Het |
| Ccdc170 |
A |
G |
10: 4,468,971 (GRCm39) |
E167G |
probably damaging |
Het |
| Cdcp3 |
T |
A |
7: 130,776,206 (GRCm39) |
|
probably null |
Het |
| Cdyl2 |
A |
G |
8: 117,305,926 (GRCm39) |
M445T |
probably damaging |
Het |
| Clca3a1 |
T |
C |
3: 144,721,605 (GRCm39) |
D322G |
probably benign |
Het |
| Cnot10 |
C |
T |
9: 114,458,202 (GRCm39) |
M101I |
possibly damaging |
Het |
| Cntrl |
C |
T |
2: 35,055,694 (GRCm39) |
T1196M |
probably benign |
Het |
| Cybb |
C |
G |
X: 9,316,989 (GRCm39) |
D246H |
probably benign |
Het |
| Dcaf6 |
T |
C |
1: 165,247,774 (GRCm39) |
D153G |
probably damaging |
Het |
| Dennd2c |
G |
A |
3: 103,039,140 (GRCm39) |
G96E |
probably benign |
Het |
| Dhrs9 |
T |
C |
2: 69,231,752 (GRCm39) |
F304S |
probably damaging |
Het |
| Dmxl1 |
T |
C |
18: 50,010,764 (GRCm39) |
S974P |
probably damaging |
Het |
| Dnah6 |
T |
C |
6: 73,169,659 (GRCm39) |
|
probably benign |
Het |
| Dnajc2 |
T |
C |
5: 21,962,338 (GRCm39) |
K621E |
probably damaging |
Het |
| Ehbp1 |
T |
C |
11: 22,096,592 (GRCm39) |
D299G |
probably benign |
Het |
| Erap1 |
A |
G |
13: 74,794,647 (GRCm39) |
E102G |
probably benign |
Het |
| Fasn |
T |
G |
11: 120,707,472 (GRCm39) |
N799T |
probably benign |
Het |
| Fbxl20 |
T |
C |
11: 98,019,186 (GRCm39) |
D22G |
probably damaging |
Het |
| Fgfr1 |
T |
C |
8: 26,053,542 (GRCm39) |
|
probably null |
Het |
| Frzb |
A |
T |
2: 80,276,871 (GRCm39) |
I105N |
probably damaging |
Het |
| Gabrb1 |
T |
A |
5: 72,026,764 (GRCm39) |
F55Y |
probably damaging |
Het |
| Gatd1 |
G |
T |
7: 140,989,010 (GRCm39) |
C216* |
probably null |
Het |
| Gnl2 |
A |
C |
4: 124,937,485 (GRCm39) |
N255T |
probably damaging |
Het |
| Golgb1 |
A |
T |
16: 36,736,480 (GRCm39) |
Q1909L |
probably benign |
Het |
| Gpnmb |
T |
C |
6: 49,028,904 (GRCm39) |
L474P |
probably damaging |
Het |
| H60b |
T |
C |
10: 22,163,115 (GRCm39) |
V230A |
possibly damaging |
Het |
| Hmcn2 |
T |
A |
2: 31,250,992 (GRCm39) |
V818D |
probably damaging |
Het |
| Irag2 |
C |
A |
6: 145,111,027 (GRCm39) |
S277R |
probably damaging |
Het |
| Itprid1 |
C |
T |
6: 55,955,175 (GRCm39) |
P928S |
possibly damaging |
Het |
| Jade2 |
G |
T |
11: 51,707,909 (GRCm39) |
T768K |
probably benign |
Het |
| Kif28 |
T |
C |
1: 179,530,085 (GRCm39) |
H692R |
probably benign |
Het |
| Kmt2b |
T |
C |
7: 30,277,942 (GRCm39) |
N1634S |
probably damaging |
Het |
| Knop1 |
A |
G |
7: 118,445,299 (GRCm39) |
W222R |
probably damaging |
Het |
| Map1b |
T |
C |
13: 99,569,808 (GRCm39) |
D971G |
unknown |
Het |
| Mapk7 |
G |
T |
11: 61,384,475 (GRCm39) |
T77K |
probably damaging |
Het |
| Mcm6 |
A |
G |
1: 128,276,714 (GRCm39) |
L292P |
probably damaging |
Het |
| Megf8 |
T |
C |
7: 25,039,089 (GRCm39) |
L900P |
probably benign |
Het |
| Meis1 |
G |
A |
11: 18,831,776 (GRCm39) |
H421Y |
possibly damaging |
Het |
| Minar2 |
A |
T |
18: 59,205,277 (GRCm39) |
I22F |
probably damaging |
Het |
| Mllt1 |
T |
C |
17: 57,206,813 (GRCm39) |
T344A |
probably benign |
Het |
| Mta1 |
T |
A |
12: 113,100,160 (GRCm39) |
S657T |
probably benign |
Het |
| Mtus1 |
C |
A |
8: 41,453,838 (GRCm39) |
K998N |
probably damaging |
Het |
| Ncdn |
G |
A |
4: 126,643,731 (GRCm39) |
L364F |
possibly damaging |
Het |
| Ndufb7 |
T |
C |
8: 84,297,534 (GRCm39) |
L63P |
probably damaging |
Het |
| Nfix |
T |
C |
8: 85,498,458 (GRCm39) |
I172V |
probably benign |
Het |
| Nos1 |
T |
C |
5: 118,085,635 (GRCm39) |
|
probably null |
Het |
| Nrp1 |
C |
A |
8: 129,229,285 (GRCm39) |
S921* |
probably null |
Het |
| Oma1 |
T |
C |
4: 103,176,727 (GRCm39) |
|
probably null |
Het |
| Or3a1b |
A |
T |
11: 74,012,705 (GRCm39) |
I197F |
probably benign |
Het |
| Or5b106 |
T |
A |
19: 13,123,355 (GRCm39) |
I223L |
possibly damaging |
Het |
| Pcp2 |
T |
A |
8: 3,675,534 (GRCm39) |
|
probably benign |
Het |
| Pdk4 |
T |
A |
6: 5,489,157 (GRCm39) |
H250L |
possibly damaging |
Het |
| Phldb3 |
A |
G |
7: 24,323,716 (GRCm39) |
H449R |
probably benign |
Het |
| Pip4k2c |
T |
C |
10: 127,035,196 (GRCm39) |
T391A |
possibly damaging |
Het |
| Polrmt |
A |
G |
10: 79,582,385 (GRCm39) |
M1T |
probably null |
Het |
| Ppfia2 |
G |
C |
10: 106,597,978 (GRCm39) |
L180F |
probably damaging |
Het |
| Prkcg |
T |
G |
7: 3,378,781 (GRCm39) |
Y624* |
probably null |
Het |
| Psmg2 |
A |
G |
18: 67,781,926 (GRCm39) |
E164G |
probably damaging |
Het |
| Rb1 |
A |
T |
14: 73,454,131 (GRCm39) |
L589H |
probably damaging |
Het |
| Rcvrn |
A |
T |
11: 67,586,591 (GRCm39) |
I117F |
probably damaging |
Het |
| Rere |
T |
A |
4: 150,703,601 (GRCm39) |
W1528R |
probably damaging |
Het |
| Robo2 |
A |
G |
16: 73,695,803 (GRCm39) |
S1447P |
possibly damaging |
Het |
| Scfd2 |
C |
A |
5: 74,623,319 (GRCm39) |
G405W |
probably damaging |
Het |
| Scin |
T |
A |
12: 40,119,373 (GRCm39) |
I552F |
possibly damaging |
Het |
| Serpina3k |
G |
A |
12: 104,309,269 (GRCm39) |
V238M |
probably damaging |
Het |
| Slc1a6 |
G |
A |
10: 78,632,085 (GRCm39) |
V304M |
probably damaging |
Het |
| Slc20a2 |
C |
T |
8: 23,051,020 (GRCm39) |
S351L |
probably damaging |
Het |
| Slc31a2 |
T |
C |
4: 62,215,325 (GRCm39) |
V124A |
probably damaging |
Het |
| Slc38a3 |
T |
C |
9: 107,533,426 (GRCm39) |
N244S |
probably benign |
Het |
| Slc4a1 |
A |
G |
11: 102,243,279 (GRCm39) |
V784A |
probably damaging |
Het |
| Slc6a5 |
T |
C |
7: 49,598,004 (GRCm39) |
F623L |
probably benign |
Het |
| Slf2 |
T |
G |
19: 44,960,100 (GRCm39) |
D1022E |
probably damaging |
Het |
| Slfn8 |
G |
A |
11: 82,907,704 (GRCm39) |
H280Y |
probably damaging |
Het |
| Smpdl3a |
A |
T |
10: 57,677,127 (GRCm39) |
D45V |
probably damaging |
Het |
| Ssh3 |
T |
C |
19: 4,315,170 (GRCm39) |
E342G |
probably damaging |
Het |
| Tacr1 |
A |
T |
6: 82,531,922 (GRCm39) |
I273F |
probably benign |
Het |
| Tfg |
T |
A |
16: 56,514,759 (GRCm39) |
|
probably null |
Het |
| Tmem179 |
A |
G |
12: 112,468,268 (GRCm39) |
L71P |
probably damaging |
Het |
| Tmem63a |
T |
A |
1: 180,794,086 (GRCm39) |
I541N |
probably benign |
Het |
| Traj20 |
G |
A |
14: 54,436,924 (GRCm39) |
|
probably benign |
Het |
| Trappc13 |
A |
T |
13: 104,290,802 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
T |
2: 76,641,587 (GRCm39) |
L5176Q |
possibly damaging |
Het |
| Tulp1 |
A |
G |
17: 28,578,109 (GRCm39) |
L310P |
probably damaging |
Het |
| Ube3d |
A |
G |
9: 86,304,925 (GRCm39) |
Y306H |
probably damaging |
Het |
| Urb1 |
A |
T |
16: 90,580,216 (GRCm39) |
V649E |
probably damaging |
Het |
| Vps13d |
A |
G |
4: 144,709,963 (GRCm39) |
L4211P |
probably damaging |
Het |
| Vwa5b1 |
T |
A |
4: 138,321,573 (GRCm39) |
I407F |
possibly damaging |
Het |
| Vwce |
G |
T |
19: 10,624,243 (GRCm39) |
C378F |
probably damaging |
Het |
| Zfp791 |
T |
A |
8: 85,837,580 (GRCm39) |
I95L |
probably benign |
Het |
|
| Other mutations in Dnah7c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00559:Dnah7c
|
APN |
1 |
46,846,449 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL02958:Dnah7c
|
APN |
1 |
46,696,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03035:Dnah7c
|
APN |
1 |
46,563,277 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL03161:Dnah7c
|
APN |
1 |
46,506,456 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL03178:Dnah7c
|
APN |
1 |
46,506,525 (GRCm39) |
missense |
probably benign |
|
|
IGL03052:Dnah7c
|
UTSW |
1 |
46,671,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0751:Dnah7c
|
UTSW |
1 |
46,505,065 (GRCm39) |
missense |
probably benign |
|
|
R1029:Dnah7c
|
UTSW |
1 |
46,651,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3104:Dnah7c
|
UTSW |
1 |
46,837,439 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3977:Dnah7c
|
UTSW |
1 |
46,668,071 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4003:Dnah7c
|
UTSW |
1 |
46,720,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4133:Dnah7c
|
UTSW |
1 |
46,705,150 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4303:Dnah7c
|
UTSW |
1 |
46,787,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4329:Dnah7c
|
UTSW |
1 |
46,688,441 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4434:Dnah7c
|
UTSW |
1 |
46,705,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4457:Dnah7c
|
UTSW |
1 |
46,779,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Dnah7c
|
UTSW |
1 |
46,787,795 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4507:Dnah7c
|
UTSW |
1 |
46,805,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4527:Dnah7c
|
UTSW |
1 |
46,572,091 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4571:Dnah7c
|
UTSW |
1 |
46,572,376 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4589:Dnah7c
|
UTSW |
1 |
46,553,743 (GRCm39) |
nonsense |
probably null |
|
|
R4731:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4732:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4747:Dnah7c
|
UTSW |
1 |
46,572,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4845:Dnah7c
|
UTSW |
1 |
46,832,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4873:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R4875:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R5241:Dnah7c
|
UTSW |
1 |
46,569,660 (GRCm39) |
missense |
probably benign |
|
|
R5279:Dnah7c
|
UTSW |
1 |
46,558,429 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5327:Dnah7c
|
UTSW |
1 |
46,704,728 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5546:Dnah7c
|
UTSW |
1 |
46,705,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Dnah7c
|
UTSW |
1 |
46,837,395 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5637:Dnah7c
|
UTSW |
1 |
46,799,521 (GRCm39) |
splice site |
probably null |
|
|
R5639:Dnah7c
|
UTSW |
1 |
46,778,828 (GRCm39) |
missense |
probably benign |
|
|
R5663:Dnah7c
|
UTSW |
1 |
46,574,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Dnah7c
|
UTSW |
1 |
46,787,826 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5759:Dnah7c
|
UTSW |
1 |
46,654,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5771:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5784:Dnah7c
|
UTSW |
1 |
46,563,228 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5800:Dnah7c
|
UTSW |
1 |
46,686,175 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5933:Dnah7c
|
UTSW |
1 |
46,558,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5948:Dnah7c
|
UTSW |
1 |
46,711,657 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6487:Dnah7c
|
UTSW |
1 |
46,808,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6536:Dnah7c
|
UTSW |
1 |
46,697,450 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,554,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6714:Dnah7c
|
UTSW |
1 |
46,779,966 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6729:Dnah7c
|
UTSW |
1 |
46,711,681 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6763:Dnah7c
|
UTSW |
1 |
46,668,050 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6866:Dnah7c
|
UTSW |
1 |
46,696,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6880:Dnah7c
|
UTSW |
1 |
46,566,831 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6988:Dnah7c
|
UTSW |
1 |
46,705,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6995:Dnah7c
|
UTSW |
1 |
46,494,973 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7007:Dnah7c
|
UTSW |
1 |
46,571,910 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7086:Dnah7c
|
UTSW |
1 |
46,789,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7128:Dnah7c
|
UTSW |
1 |
46,566,645 (GRCm39) |
missense |
probably benign |
|
|
R7131:Dnah7c
|
UTSW |
1 |
46,720,932 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7135:Dnah7c
|
UTSW |
1 |
46,572,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Dnah7c
|
UTSW |
1 |
46,719,898 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7176:Dnah7c
|
UTSW |
1 |
46,469,969 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7221:Dnah7c
|
UTSW |
1 |
46,494,937 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7310:Dnah7c
|
UTSW |
1 |
46,636,127 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,819,935 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,823,608 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7404:Dnah7c
|
UTSW |
1 |
46,705,223 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7452:Dnah7c
|
UTSW |
1 |
46,686,196 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7515:Dnah7c
|
UTSW |
1 |
46,496,450 (GRCm39) |
missense |
probably benign |
|
|
R7534:Dnah7c
|
UTSW |
1 |
46,809,227 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7542:Dnah7c
|
UTSW |
1 |
46,823,658 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7605:Dnah7c
|
UTSW |
1 |
46,671,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Dnah7c
|
UTSW |
1 |
46,641,973 (GRCm39) |
missense |
probably benign |
|
|
R7770:Dnah7c
|
UTSW |
1 |
46,665,460 (GRCm39) |
splice site |
probably null |
|
|
R7884:Dnah7c
|
UTSW |
1 |
46,830,929 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7899:Dnah7c
|
UTSW |
1 |
46,553,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8025:Dnah7c
|
UTSW |
1 |
46,496,456 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8057:Dnah7c
|
UTSW |
1 |
46,728,112 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8191:Dnah7c
|
UTSW |
1 |
46,646,618 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8255:Dnah7c
|
UTSW |
1 |
46,698,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8428:Dnah7c
|
UTSW |
1 |
46,711,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8441:Dnah7c
|
UTSW |
1 |
46,572,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Dnah7c
|
UTSW |
1 |
46,719,952 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8559:Dnah7c
|
UTSW |
1 |
46,764,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8752:Dnah7c
|
UTSW |
1 |
46,711,701 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8869:Dnah7c
|
UTSW |
1 |
46,671,504 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9058:Dnah7c
|
UTSW |
1 |
46,805,816 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,816,896 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,704,650 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9246:Dnah7c
|
UTSW |
1 |
46,571,934 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9319:Dnah7c
|
UTSW |
1 |
46,521,168 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9388:Dnah7c
|
UTSW |
1 |
46,779,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,654,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,506,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,799,476 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,686,152 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Dnah7c
|
UTSW |
1 |
46,693,263 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCCATAATCTTTGTTCTACTAAGTGA -3'
(R):5'- GAAATGTGACCAGATGAGTGCAG -3'
Sequencing Primer
(F):5'- CACACAGTAACTTGGTCCTGAGTTG -3'
(R):5'- AGATGAGTGCAGCTGAGCCTC -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation