Incidental Mutation 'R0244:Ep300'
| ID |
38015 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ep300
|
| Ensembl Gene |
ENSMUSG00000055024 |
| Gene Name |
E1A binding protein p300 |
| Synonyms |
KAT3B, p300 |
| MMRRC Submission |
038482-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0244 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
81585351-81652077 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 81640128 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Serine
at position 1386
(P1386S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066789
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068387]
|
| AlphaFold |
B2RWS6 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000068387
AA Change: P1386S
|
| SMART Domains |
Protein: ENSMUSP00000066789
Gene: ENSMUSG00000055024
AA Change: P1386S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
242 |
N/A |
INTRINSIC |
|
low complexity region
|
296 |
309 |
N/A |
INTRINSIC |
|
ZnF_TAZ
|
333 |
418 |
2.85e-32 |
SMART |
|
low complexity region
|
475 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
503 |
N/A |
INTRINSIC |
|
Pfam:KIX
|
567 |
647 |
7.2e-44 |
PFAM |
|
low complexity region
|
722 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
831 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
852 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
924 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
1024 |
1039 |
N/A |
INTRINSIC |
|
BROMO
|
1047 |
1157 |
6.36e-42 |
SMART |
|
Blast:KAT11
|
1227 |
1300 |
9e-22 |
BLAST |
|
KAT11
|
1305 |
1610 |
1.19e-140 |
SMART |
|
ZnF_ZZ
|
1663 |
1704 |
2.67e-15 |
SMART |
|
ZnF_TAZ
|
1728 |
1806 |
5.53e-30 |
SMART |
|
low complexity region
|
1810 |
1836 |
N/A |
INTRINSIC |
|
low complexity region
|
1847 |
1881 |
N/A |
INTRINSIC |
|
low complexity region
|
1902 |
1927 |
N/A |
INTRINSIC |
|
low complexity region
|
1962 |
1979 |
N/A |
INTRINSIC |
|
Pfam:Creb_binding
|
1993 |
2099 |
3.5e-37 |
PFAM |
|
low complexity region
|
2146 |
2158 |
N/A |
INTRINSIC |
|
low complexity region
|
2187 |
2203 |
N/A |
INTRINSIC |
|
low complexity region
|
2205 |
2244 |
N/A |
INTRINSIC |
|
low complexity region
|
2254 |
2265 |
N/A |
INTRINSIC |
|
low complexity region
|
2303 |
2346 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2405 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000187776
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205816
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206431
|
| Meta Mutation Damage Score |
0.1442 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.5%
|
| Validation Efficiency |
99% (88/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for a targeted null mutation exhibit defects of the heart, lung, and small intestine and die at midgestation; heterozygotes also show some embryonic loss. Heterozygotes for an acetyltransferase-negative mutation die by the neonatal period. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610507B11Rik |
T |
A |
11: 78,286,491 (GRCm38) |
|
probably null |
Het |
| Adamdec1 |
A |
T |
14: 68,568,723 (GRCm38) |
C434* |
probably null |
Het |
| Adprhl1 |
A |
G |
8: 13,242,391 (GRCm38) |
|
probably benign |
Het |
| Ago1 |
T |
A |
4: 126,463,706 (GRCm38) |
I59F |
possibly damaging |
Het |
| Arel1 |
T |
C |
12: 84,920,693 (GRCm38) |
T786A |
probably damaging |
Het |
| Arhgap26 |
A |
G |
18: 39,363,131 (GRCm38) |
K117R |
probably benign |
Het |
| Atp6v0b |
C |
T |
4: 117,884,622 (GRCm38) |
G204D |
probably damaging |
Het |
| Bace2 |
T |
A |
16: 97,436,773 (GRCm38) |
|
probably null |
Het |
| Camk4 |
G |
A |
18: 33,179,625 (GRCm38) |
|
probably null |
Het |
| Cdh26 |
C |
T |
2: 178,481,632 (GRCm38) |
R675C |
possibly damaging |
Het |
| Cep152 |
T |
C |
2: 125,564,214 (GRCm38) |
E1466G |
probably benign |
Het |
| Ces3b |
T |
C |
8: 105,092,635 (GRCm38) |
F441S |
probably damaging |
Het |
| Cfap52 |
T |
C |
11: 67,926,382 (GRCm38) |
T562A |
possibly damaging |
Het |
| Clca3a2 |
C |
A |
3: 144,813,898 (GRCm38) |
M238I |
possibly damaging |
Het |
| Cntnap5c |
A |
T |
17: 58,102,168 (GRCm38) |
D467V |
probably damaging |
Het |
| Col7a1 |
T |
A |
9: 108,972,184 (GRCm38) |
|
probably null |
Het |
| Cstf1 |
A |
G |
2: 172,377,710 (GRCm38) |
N247S |
possibly damaging |
Het |
| Dffb |
G |
T |
4: 153,974,615 (GRCm38) |
N68K |
probably benign |
Het |
| Duox2 |
C |
T |
2: 122,291,860 (GRCm38) |
G595S |
probably benign |
Het |
| Eftud2 |
T |
A |
11: 102,864,725 (GRCm38) |
I228F |
probably damaging |
Het |
| Elmo3 |
T |
C |
8: 105,309,171 (GRCm38) |
V578A |
probably benign |
Het |
| Elp2 |
A |
G |
18: 24,631,471 (GRCm38) |
D625G |
possibly damaging |
Het |
| Fam120b |
A |
G |
17: 15,417,637 (GRCm38) |
D610G |
probably damaging |
Het |
| Fastk |
A |
T |
5: 24,442,178 (GRCm38) |
|
probably benign |
Het |
| Fbxl6 |
A |
G |
15: 76,537,191 (GRCm38) |
S252P |
probably damaging |
Het |
| Fbxo43 |
T |
C |
15: 36,161,793 (GRCm38) |
K423E |
probably damaging |
Het |
| Filip1 |
T |
A |
9: 79,819,462 (GRCm38) |
E625V |
possibly damaging |
Het |
| Fkbp9 |
T |
A |
6: 56,856,378 (GRCm38) |
Y283* |
probably null |
Het |
| Gigyf2 |
T |
A |
1: 87,379,015 (GRCm38) |
D142E |
possibly damaging |
Het |
| Gm10142 |
T |
C |
10: 77,716,014 (GRCm38) |
|
probably null |
Het |
| Golga5 |
T |
C |
12: 102,476,188 (GRCm38) |
V262A |
probably benign |
Het |
| Hectd4 |
T |
C |
5: 121,329,605 (GRCm38) |
V2539A |
probably benign |
Het |
| Ica1 |
G |
T |
6: 8,653,632 (GRCm38) |
S335* |
probably null |
Het |
| Itga1 |
A |
T |
13: 115,006,897 (GRCm38) |
|
probably benign |
Het |
| Itgb1 |
T |
C |
8: 128,717,685 (GRCm38) |
|
probably benign |
Het |
| Itpr1 |
G |
A |
6: 108,473,589 (GRCm38) |
V1960I |
probably benign |
Het |
| Kcnh4 |
C |
T |
11: 100,746,932 (GRCm38) |
G633E |
probably benign |
Het |
| Kprp |
C |
T |
3: 92,825,411 (GRCm38) |
V111I |
probably benign |
Het |
| Lamc3 |
T |
C |
2: 31,940,721 (GRCm38) |
I1490T |
probably damaging |
Het |
| Lcp1 |
A |
T |
14: 75,227,001 (GRCm38) |
D554V |
possibly damaging |
Het |
| Lgi3 |
A |
G |
14: 70,534,698 (GRCm38) |
T228A |
probably benign |
Het |
| Lipa |
A |
T |
19: 34,501,541 (GRCm38) |
F260I |
probably damaging |
Het |
| Lrriq1 |
C |
T |
10: 103,215,773 (GRCm38) |
E373K |
probably damaging |
Het |
| Map6 |
G |
A |
7: 99,336,836 (GRCm38) |
G649D |
probably benign |
Het |
| Mccc1 |
A |
G |
3: 35,990,047 (GRCm38) |
|
probably null |
Het |
| Mical3 |
A |
T |
6: 120,957,722 (GRCm38) |
S1799T |
probably benign |
Het |
| Mmp23 |
T |
A |
4: 155,652,132 (GRCm38) |
T151S |
probably damaging |
Het |
| Myo1d |
T |
A |
11: 80,674,708 (GRCm38) |
N401I |
probably damaging |
Het |
| Myo9b |
T |
A |
8: 71,321,813 (GRCm38) |
S323T |
probably damaging |
Het |
| Nbn |
G |
T |
4: 15,979,353 (GRCm38) |
W446L |
probably benign |
Het |
| Nedd1 |
A |
T |
10: 92,716,265 (GRCm38) |
|
probably benign |
Het |
| Ngef |
C |
A |
1: 87,487,962 (GRCm38) |
|
probably benign |
Het |
| Nup153 |
A |
T |
13: 46,693,936 (GRCm38) |
N672K |
probably benign |
Het |
| Olfr1308 |
T |
C |
2: 111,961,016 (GRCm38) |
N19S |
probably benign |
Het |
| Olfr149 |
T |
A |
9: 39,702,173 (GRCm38) |
I199F |
probably damaging |
Het |
| Olfr1509 |
T |
C |
14: 52,450,512 (GRCm38) |
V33A |
probably benign |
Het |
| Olfr372 |
C |
T |
8: 72,058,400 (GRCm38) |
T240M |
probably damaging |
Het |
| Palm2 |
T |
G |
4: 57,710,177 (GRCm38) |
V374G |
possibly damaging |
Het |
| Pdlim3 |
C |
A |
8: 45,908,460 (GRCm38) |
|
probably benign |
Het |
| Pmfbp1 |
G |
A |
8: 109,541,673 (GRCm38) |
E951K |
probably damaging |
Het |
| Pop1 |
T |
A |
15: 34,515,891 (GRCm38) |
C548* |
probably null |
Het |
| Ppp1r16a |
C |
T |
15: 76,690,799 (GRCm38) |
|
probably benign |
Het |
| Ptpdc1 |
A |
T |
13: 48,585,980 (GRCm38) |
N658K |
probably benign |
Het |
| Ptprk |
A |
C |
10: 28,206,225 (GRCm38) |
E63D |
possibly damaging |
Het |
| Rtf1 |
C |
T |
2: 119,732,877 (GRCm38) |
R712W |
probably damaging |
Het |
| Samd7 |
A |
C |
3: 30,751,073 (GRCm38) |
T2P |
probably benign |
Het |
| Sft2d1 |
A |
G |
17: 8,319,422 (GRCm38) |
T52A |
probably benign |
Het |
| Slc25a26 |
A |
G |
6: 94,510,833 (GRCm38) |
H91R |
probably damaging |
Het |
| Slc5a4a |
A |
G |
10: 76,189,152 (GRCm38) |
E621G |
possibly damaging |
Het |
| Slf1 |
A |
T |
13: 77,126,632 (GRCm38) |
L28* |
probably null |
Het |
| Snapc1 |
C |
T |
12: 73,975,032 (GRCm38) |
R81C |
probably damaging |
Het |
| Sorcs2 |
G |
A |
5: 36,397,553 (GRCm38) |
|
probably benign |
Het |
| Tacc2 |
T |
C |
7: 130,751,825 (GRCm38) |
|
probably benign |
Het |
| Tas2r140 |
A |
G |
6: 133,055,327 (GRCm38) |
V156A |
possibly damaging |
Het |
| Terf2ip |
C |
A |
8: 112,018,164 (GRCm38) |
T371K |
possibly damaging |
Het |
| Tifa |
C |
T |
3: 127,796,888 (GRCm38) |
L103F |
probably damaging |
Het |
| Tmco3 |
A |
G |
8: 13,292,037 (GRCm38) |
N104D |
probably damaging |
Het |
| Tmem259 |
T |
A |
10: 79,978,963 (GRCm38) |
D240V |
probably damaging |
Het |
| Trim60 |
C |
T |
8: 65,001,048 (GRCm38) |
R183H |
probably benign |
Het |
| Trps1 |
T |
C |
15: 50,664,743 (GRCm38) |
N725D |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,814,806 (GRCm38) |
V12902M |
probably damaging |
Het |
| Ubxn4 |
G |
A |
1: 128,262,904 (GRCm38) |
E256K |
probably benign |
Het |
| Unc79 |
A |
G |
12: 103,112,891 (GRCm38) |
K1772E |
probably damaging |
Het |
| Vwde |
C |
T |
6: 13,193,126 (GRCm38) |
V405I |
probably benign |
Het |
| Wdr18 |
T |
A |
10: 79,966,408 (GRCm38) |
D290E |
probably damaging |
Het |
| Wdr92 |
T |
C |
11: 17,229,851 (GRCm38) |
L284P |
probably damaging |
Het |
| Wwc2 |
G |
A |
8: 47,900,721 (GRCm38) |
A126V |
probably benign |
Het |
| Zfp882 |
A |
T |
8: 71,913,523 (GRCm38) |
I105F |
possibly damaging |
Het |
| Zfp942 |
A |
T |
17: 21,928,572 (GRCm38) |
C359S |
probably benign |
Het |
|
| Other mutations in Ep300 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Ep300
|
APN |
15 |
81,641,418 (GRCm38) |
missense |
unknown |
|
|
IGL01128:Ep300
|
APN |
15 |
81,630,006 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01151:Ep300
|
APN |
15 |
81,623,472 (GRCm38) |
intron |
probably benign |
|
|
IGL01414:Ep300
|
APN |
15 |
81,627,266 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01564:Ep300
|
APN |
15 |
81,632,464 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01875:Ep300
|
APN |
15 |
81,640,023 (GRCm38) |
missense |
unknown |
|
|
IGL01945:Ep300
|
APN |
15 |
81,616,109 (GRCm38) |
unclassified |
probably benign |
|
|
IGL02022:Ep300
|
APN |
15 |
81,611,437 (GRCm38) |
unclassified |
probably benign |
|
|
IGL02115:Ep300
|
APN |
15 |
81,648,818 (GRCm38) |
missense |
unknown |
|
|
IGL02129:Ep300
|
APN |
15 |
81,586,636 (GRCm38) |
missense |
unknown |
|
|
IGL02145:Ep300
|
APN |
15 |
81,601,166 (GRCm38) |
missense |
unknown |
|
|
IGL02149:Ep300
|
APN |
15 |
81,628,420 (GRCm38) |
unclassified |
probably benign |
|
|
IGL02165:Ep300
|
APN |
15 |
81,641,391 (GRCm38) |
missense |
probably benign |
0.39 |
|
IGL02226:Ep300
|
APN |
15 |
81,613,412 (GRCm38) |
missense |
unknown |
|
|
IGL02610:Ep300
|
APN |
15 |
81,601,522 (GRCm38) |
missense |
unknown |
|
|
IGL02731:Ep300
|
APN |
15 |
81,648,414 (GRCm38) |
missense |
unknown |
|
|
IGL03239:Ep300
|
APN |
15 |
81,641,388 (GRCm38) |
missense |
unknown |
|
|
BB001:Ep300
|
UTSW |
15 |
81,649,502 (GRCm38) |
missense |
unknown |
|
|
BB011:Ep300
|
UTSW |
15 |
81,649,502 (GRCm38) |
missense |
unknown |
|
|
R0077:Ep300
|
UTSW |
15 |
81,641,313 (GRCm38) |
missense |
unknown |
|
|
R0145:Ep300
|
UTSW |
15 |
81,616,127 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0390:Ep300
|
UTSW |
15 |
81,640,116 (GRCm38) |
missense |
unknown |
|
|
R0534:Ep300
|
UTSW |
15 |
81,600,896 (GRCm38) |
splice site |
probably benign |
|
|
R0671:Ep300
|
UTSW |
15 |
81,616,134 (GRCm38) |
unclassified |
probably benign |
|
|
R0840:Ep300
|
UTSW |
15 |
81,644,933 (GRCm38) |
missense |
unknown |
|
|
R1166:Ep300
|
UTSW |
15 |
81,630,064 (GRCm38) |
unclassified |
probably benign |
|
|
R1737:Ep300
|
UTSW |
15 |
81,626,347 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1893:Ep300
|
UTSW |
15 |
81,631,646 (GRCm38) |
unclassified |
probably benign |
|
|
R2136:Ep300
|
UTSW |
15 |
81,640,447 (GRCm38) |
missense |
unknown |
|
|
R3427:Ep300
|
UTSW |
15 |
81,601,279 (GRCm38) |
missense |
unknown |
|
|
R3757:Ep300
|
UTSW |
15 |
81,648,589 (GRCm38) |
missense |
unknown |
|
|
R3892:Ep300
|
UTSW |
15 |
81,619,997 (GRCm38) |
unclassified |
probably benign |
|
|
R4554:Ep300
|
UTSW |
15 |
81,601,430 (GRCm38) |
missense |
unknown |
|
|
R4575:Ep300
|
UTSW |
15 |
81,611,410 (GRCm38) |
unclassified |
probably benign |
|
|
R4575:Ep300
|
UTSW |
15 |
81,649,009 (GRCm38) |
missense |
unknown |
|
|
R4577:Ep300
|
UTSW |
15 |
81,611,410 (GRCm38) |
unclassified |
probably benign |
|
|
R4577:Ep300
|
UTSW |
15 |
81,649,009 (GRCm38) |
missense |
unknown |
|
|
R4578:Ep300
|
UTSW |
15 |
81,611,410 (GRCm38) |
unclassified |
probably benign |
|
|
R4578:Ep300
|
UTSW |
15 |
81,649,009 (GRCm38) |
missense |
unknown |
|
|
R5021:Ep300
|
UTSW |
15 |
81,640,023 (GRCm38) |
missense |
unknown |
|
|
R5366:Ep300
|
UTSW |
15 |
81,616,100 (GRCm38) |
missense |
probably benign |
0.24 |
|
R5372:Ep300
|
UTSW |
15 |
81,636,830 (GRCm38) |
missense |
unknown |
|
|
R5393:Ep300
|
UTSW |
15 |
81,631,618 (GRCm38) |
unclassified |
probably benign |
|
|
R5410:Ep300
|
UTSW |
15 |
81,648,854 (GRCm38) |
missense |
unknown |
|
|
R5571:Ep300
|
UTSW |
15 |
81,643,217 (GRCm38) |
intron |
probably benign |
|
|
R5701:Ep300
|
UTSW |
15 |
81,601,495 (GRCm38) |
missense |
unknown |
|
|
R5772:Ep300
|
UTSW |
15 |
81,639,914 (GRCm38) |
intron |
probably benign |
|
|
R5825:Ep300
|
UTSW |
15 |
81,611,472 (GRCm38) |
missense |
probably benign |
0.39 |
|
R5917:Ep300
|
UTSW |
15 |
81,628,607 (GRCm38) |
unclassified |
probably benign |
|
|
R5991:Ep300
|
UTSW |
15 |
81,648,466 (GRCm38) |
missense |
unknown |
|
|
R6019:Ep300
|
UTSW |
15 |
81,641,382 (GRCm38) |
missense |
unknown |
|
|
R6144:Ep300
|
UTSW |
15 |
81,601,234 (GRCm38) |
missense |
unknown |
|
|
R6291:Ep300
|
UTSW |
15 |
81,648,507 (GRCm38) |
missense |
unknown |
|
|
R6292:Ep300
|
UTSW |
15 |
81,616,734 (GRCm38) |
unclassified |
probably benign |
|
|
R6599:Ep300
|
UTSW |
15 |
81,586,713 (GRCm38) |
missense |
unknown |
|
|
R6804:Ep300
|
UTSW |
15 |
81,641,311 (GRCm38) |
nonsense |
probably null |
|
|
R6925:Ep300
|
UTSW |
15 |
81,649,981 (GRCm38) |
missense |
probably benign |
0.32 |
|
R7327:Ep300
|
UTSW |
15 |
81,627,314 (GRCm38) |
missense |
unknown |
|
|
R7378:Ep300
|
UTSW |
15 |
81,650,545 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7388:Ep300
|
UTSW |
15 |
81,648,366 (GRCm38) |
missense |
unknown |
|
|
R7419:Ep300
|
UTSW |
15 |
81,648,514 (GRCm38) |
missense |
unknown |
|
|
R7498:Ep300
|
UTSW |
15 |
81,639,843 (GRCm38) |
missense |
unknown |
|
|
R7584:Ep300
|
UTSW |
15 |
81,628,426 (GRCm38) |
missense |
unknown |
|
|
R7605:Ep300
|
UTSW |
15 |
81,621,152 (GRCm38) |
missense |
unknown |
|
|
R7619:Ep300
|
UTSW |
15 |
81,608,198 (GRCm38) |
missense |
unknown |
|
|
R7699:Ep300
|
UTSW |
15 |
81,586,393 (GRCm38) |
start gained |
probably benign |
|
|
R7763:Ep300
|
UTSW |
15 |
81,586,583 (GRCm38) |
start gained |
probably benign |
|
|
R7775:Ep300
|
UTSW |
15 |
81,586,686 (GRCm38) |
missense |
unknown |
|
|
R7778:Ep300
|
UTSW |
15 |
81,586,686 (GRCm38) |
missense |
unknown |
|
|
R7862:Ep300
|
UTSW |
15 |
81,650,753 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7924:Ep300
|
UTSW |
15 |
81,649,502 (GRCm38) |
missense |
unknown |
|
|
R8155:Ep300
|
UTSW |
15 |
81,621,068 (GRCm38) |
missense |
unknown |
|
|
R8259:Ep300
|
UTSW |
15 |
81,639,017 (GRCm38) |
missense |
unknown |
|
|
R8276:Ep300
|
UTSW |
15 |
81,650,028 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R8331:Ep300
|
UTSW |
15 |
81,601,210 (GRCm38) |
missense |
unknown |
|
|
R8554:Ep300
|
UTSW |
15 |
81,639,027 (GRCm38) |
missense |
unknown |
|
|
R9019:Ep300
|
UTSW |
15 |
81,648,529 (GRCm38) |
missense |
unknown |
|
|
R9128:Ep300
|
UTSW |
15 |
81,649,745 (GRCm38) |
missense |
unknown |
|
|
R9379:Ep300
|
UTSW |
15 |
81,648,559 (GRCm38) |
missense |
unknown |
|
|
R9380:Ep300
|
UTSW |
15 |
81,616,044 (GRCm38) |
missense |
unknown |
|
|
R9484:Ep300
|
UTSW |
15 |
81,636,825 (GRCm38) |
missense |
unknown |
|
|
R9659:Ep300
|
UTSW |
15 |
81,621,072 (GRCm38) |
missense |
unknown |
|
|
R9690:Ep300
|
UTSW |
15 |
81,636,195 (GRCm38) |
missense |
unknown |
|
|
R9721:Ep300
|
UTSW |
15 |
81,608,315 (GRCm38) |
missense |
unknown |
|
|
RF020:Ep300
|
UTSW |
15 |
81,586,571 (GRCm38) |
start gained |
probably benign |
|
|
Z1177:Ep300
|
UTSW |
15 |
81,630,097 (GRCm38) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTGCCATCTACCAGACTTGGGACC -3'
(R):5'- TCCGCAAGCATTTAGGACGGAAG -3'
Sequencing Primer
(F):5'- CTGAATCAGGAGAGGTCACTGTTC -3'
(R):5'- CGAGGTAAGATATGTATACCCTCC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation