Mutagenetix > Incidental Mutation

Incidental Mutation 'R4933:Dnah8'

380743

Institutional Source

Beutler Lab

Gene Symbol

Dnah8

Ensembl Gene

ENSMUSG00000033826

Gene Name

dynein, axonemal, heavy chain 8

Synonyms

Dnahc8, P1-Loop, Hst6.7b

MMRRC Submission

042533-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.423) question?

Stock #

R4933 (G1)

Quality Score

168

Status

Validated

Chromosome

Chromosomal Location

30624354-30875264 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 30748568 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Asparagine at position 2585 (D2585N)

Ref Sequence

ENSEMBL: ENSMUSP00000127878 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170651]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000170651
AA Change: D2585N

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000127878
Gene: ENSMUSG00000033826
AA Change: D2585N

Domain	Start	End	E-Value	Type
low complexity region	2	54	N/A	INTRINSIC
Pfam:DHC_N1	379	936	8.4e-159	PFAM
low complexity region	1069	1080	N/A	INTRINSIC
low complexity region	1224	1237	N/A	INTRINSIC
Pfam:DHC_N2	1509	1917	1.6e-134	PFAM
AAA	2082	2226	1.38e-1	SMART
AAA	2363	2516	2.04e-1	SMART
AAA	2689	2837	8.15e-2	SMART
Pfam:AAA_8	3022	3294	4e-72	PFAM
Pfam:MT	3306	3656	3.6e-48	PFAM
Pfam:AAA_9	3676	3901	6.7e-85	PFAM
Pfam:Dynein_heavy	4039	4728	8.4e-250	PFAM

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 95.4%
20x: 89.3%

Validation Efficiency

97% (73/75)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012]

Allele List at MGI

Other mutations in this stock

Total: 55 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610021A01Rik	A	G	7: 41,626,802 (GRCm38)	E643G	probably damaging	Het
4430402I18Rik	G	T	19: 28,941,775 (GRCm38)	H195N	possibly damaging	Het
Abca2	T	C	2: 25,444,827 (GRCm38)	V1937A	probably benign	Het
Acot10	A	T	15: 20,666,330 (GRCm38)	N108K	possibly damaging	Het
Agtpbp1	A	T	13: 59,500,572 (GRCm38)	M478K	probably benign	Het
Akirin1	G	A	4: 123,736,858 (GRCm38)	S191F	probably damaging	Het
Aurkb	T	C	11: 69,048,144 (GRCm38)		probably benign	Het
Cabyr	T	C	18: 12,744,492 (GRCm38)		probably benign	Het
Ccp110	A	G	7: 118,725,319 (GRCm38)	E688G	probably damaging	Het
Champ1	T	A	8: 13,879,137 (GRCm38)	S432T	probably benign	Het
Crybg1	T	A	10: 43,999,213 (GRCm38)	N633I	probably damaging	Het
Dagla	A	T	19: 10,269,715 (GRCm38)		probably null	Het
Dkkl1	A	T	7: 45,211,525 (GRCm38)	L10Q	probably null	Het
E430018J23Rik	A	G	7: 127,393,349 (GRCm38)	Y30H	probably damaging	Het
Fndc7	G	T	3: 108,876,670 (GRCm38)	Q208K	probably benign	Het
Gins4	A	T	8: 23,234,780 (GRCm38)	C53S	probably damaging	Het
Gja8	T	A	3: 96,919,035 (GRCm38)		probably benign	Het
Golph3l	T	A	3: 95,617,423 (GRCm38)	N328K	probably benign	Het
Haus6	A	C	4: 86,585,287 (GRCm38)		probably benign	Het
Hdac5	A	G	11: 102,200,563 (GRCm38)		probably benign	Het
Ide	A	G	19: 37,277,756 (GRCm38)	Y883H	unknown	Het
Igf2r	A	G	17: 12,691,877 (GRCm38)		probably null	Het
Kdm3b	T	C	18: 34,810,393 (GRCm38)	Y723H	probably damaging	Het
Kif21b	G	A	1: 136,151,325 (GRCm38)		probably null	Het
Lancl1	A	T	1: 67,021,034 (GRCm38)	N77K	probably benign	Het
Lyst	T	A	13: 13,637,764 (GRCm38)	N920K	probably damaging	Het
Lyst	G	A	13: 13,759,378 (GRCm38)	V3554I	probably benign	Het
Map1a	G	A	2: 121,305,905 (GRCm38)	A2163T	probably damaging	Het
Mapk7	G	T	11: 61,493,908 (GRCm38)		probably benign	Het
Myo10	C	A	15: 25,781,118 (GRCm38)	Q154K	probably damaging	Het
Olfr13	C	T	6: 43,174,321 (GRCm38)	L112F	probably benign	Het
Olfr132	A	G	17: 38,130,550 (GRCm38)	I214T	probably damaging	Het
Pcdhgb2	G	A	18: 37,692,214 (GRCm38)	V753M	probably benign	Het
Pnn	T	A	12: 59,070,227 (GRCm38)	L195Q	probably damaging	Het
Pot1a	A	G	6: 25,771,541 (GRCm38)	V227A	possibly damaging	Het
Ppp1r21	T	A	17: 88,547,621 (GRCm38)	D109E	probably benign	Het
Prr15l	G	A	11: 96,934,762 (GRCm38)	G73S	probably damaging	Het
Rnf148	A	G	6: 23,654,340 (GRCm38)	F219S	probably benign	Het
Rnpep	C	A	1: 135,267,026 (GRCm38)		probably benign	Het
Ryr1	T	C	7: 29,104,298 (GRCm38)	T643A	probably damaging	Het
Ryr2	A	T	13: 11,945,945 (GRCm38)	C36S	probably damaging	Het
Shc3	G	T	13: 51,442,769 (GRCm38)	T406N	probably benign	Het
Slit3	G	T	11: 35,688,593 (GRCm38)	G1199V	probably damaging	Het
Sptbn5	G	A	2: 120,050,120 (GRCm38)		noncoding transcript	Het
St8sia6	T	C	2: 13,665,442 (GRCm38)	N236D	probably damaging	Het
Stpg1	A	T	4: 135,506,416 (GRCm38)	Q3L	probably benign	Het
Sult3a1	T	A	10: 33,866,554 (GRCm38)	I59N	probably damaging	Het
Svs1	T	C	6: 48,987,492 (GRCm38)	S145P	probably damaging	Het
Vmn1r208	T	G	13: 22,772,788 (GRCm38)	I180L	probably benign	Het
Vmn2r51	A	T	7: 10,098,320 (GRCm38)	N446K	probably damaging	Het
Vmn2r63	A	T	7: 42,903,978 (GRCm38)	I618N	probably damaging	Het
Wrn	T	C	8: 33,322,343 (GRCm38)	N182S	probably benign	Het
Zfp296	G	T	7: 19,579,712 (GRCm38)	C164F	possibly damaging	Het
Zmynd8	A	G	2: 165,834,951 (GRCm38)	V249A	possibly damaging	Het
Zswim2	A	G	2: 83,925,227 (GRCm38)	L110P	probably damaging	Het

Other mutations in Dnah8

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00498:Dnah8	APN	17	30,677,176 (GRCm38)	missense	probably benign	0.06
IGL00508:Dnah8	APN	17	30,855,930 (GRCm38)	missense	probably damaging	1.00
IGL00547:Dnah8	APN	17	30,815,703 (GRCm38)	nonsense	probably null
IGL00551:Dnah8	APN	17	30,663,478 (GRCm38)	nonsense	probably null
IGL00732:Dnah8	APN	17	30,656,641 (GRCm38)	missense	probably damaging	1.00
IGL00775:Dnah8	APN	17	30,767,906 (GRCm38)	nonsense	probably null
IGL00840:Dnah8	APN	17	30,790,941 (GRCm38)	missense	probably damaging	1.00
IGL00845:Dnah8	APN	17	30,819,276 (GRCm38)	critical splice donor site	probably null
IGL00953:Dnah8	APN	17	30,706,457 (GRCm38)	nonsense	probably null
IGL00976:Dnah8	APN	17	30,851,710 (GRCm38)	missense	probably damaging	0.98
IGL01395:Dnah8	APN	17	30,636,005 (GRCm38)	missense	probably benign	0.06
IGL01467:Dnah8	APN	17	30,779,916 (GRCm38)	missense	probably damaging	1.00
IGL01469:Dnah8	APN	17	30,683,714 (GRCm38)	splice site	probably benign
IGL01515:Dnah8	APN	17	30,648,485 (GRCm38)	missense	probably benign
IGL01723:Dnah8	APN	17	30,708,471 (GRCm38)	missense	probably damaging	1.00
IGL01837:Dnah8	APN	17	30,751,591 (GRCm38)	critical splice donor site	probably null
IGL01921:Dnah8	APN	17	30,736,141 (GRCm38)	missense	probably benign
IGL01958:Dnah8	APN	17	30,855,895 (GRCm38)	splice site	probably benign
IGL01968:Dnah8	APN	17	30,656,598 (GRCm38)	nonsense	probably null
IGL02093:Dnah8	APN	17	30,717,880 (GRCm38)	missense	probably damaging	0.99
IGL02151:Dnah8	APN	17	30,648,417 (GRCm38)	missense	possibly damaging	0.50
IGL02182:Dnah8	APN	17	30,794,763 (GRCm38)	missense	possibly damaging	0.45
IGL02233:Dnah8	APN	17	30,706,513 (GRCm38)	critical splice donor site	probably null
IGL02236:Dnah8	APN	17	30,649,773 (GRCm38)	nonsense	probably null
IGL02259:Dnah8	APN	17	30,759,614 (GRCm38)	missense	probably benign
IGL02263:Dnah8	APN	17	30,729,165 (GRCm38)	missense	probably benign	0.00
IGL02303:Dnah8	APN	17	30,713,047 (GRCm38)	missense	probably benign	0.03
IGL02341:Dnah8	APN	17	30,747,257 (GRCm38)	missense	probably damaging	1.00
IGL02351:Dnah8	APN	17	30,767,811 (GRCm38)	missense	probably damaging	1.00
IGL02358:Dnah8	APN	17	30,767,811 (GRCm38)	missense	probably damaging	1.00
IGL02377:Dnah8	APN	17	30,794,796 (GRCm38)	missense	probably damaging	0.98
IGL02390:Dnah8	APN	17	30,830,845 (GRCm38)	missense	probably benign	0.01
IGL02392:Dnah8	APN	17	30,818,051 (GRCm38)	splice site	probably benign
IGL02414:Dnah8	APN	17	30,700,413 (GRCm38)	missense	probably benign
IGL02455:Dnah8	APN	17	30,672,334 (GRCm38)	missense	probably damaging	0.99
IGL02817:Dnah8	APN	17	30,668,295 (GRCm38)	missense	probably benign
IGL02831:Dnah8	APN	17	30,712,276 (GRCm38)	missense	probably benign	0.23
IGL02863:Dnah8	APN	17	30,769,697 (GRCm38)	missense	probably damaging	1.00
IGL02894:Dnah8	APN	17	30,721,110 (GRCm38)	nonsense	probably null
IGL02954:Dnah8	APN	17	30,704,835 (GRCm38)	missense	probably benign	0.30
IGL02964:Dnah8	APN	17	30,746,761 (GRCm38)	missense	probably damaging	1.00
IGL03080:Dnah8	APN	17	30,719,006 (GRCm38)	missense	probably benign	0.01
IGL03081:Dnah8	APN	17	30,686,373 (GRCm38)	splice site	probably benign
IGL03086:Dnah8	APN	17	30,742,780 (GRCm38)	missense	probably damaging	1.00
IGL03087:Dnah8	APN	17	30,784,144 (GRCm38)	missense	probably benign
IGL03176:Dnah8	APN	17	30,694,037 (GRCm38)	missense	probably benign
IGL03191:Dnah8	APN	17	30,726,830 (GRCm38)	missense	probably damaging	0.99
IGL03210:Dnah8	APN	17	30,815,665 (GRCm38)	missense	probably damaging	0.96
IGL03252:Dnah8	APN	17	30,673,920 (GRCm38)	splice site	probably null
IGL03255:Dnah8	APN	17	30,741,381 (GRCm38)	missense	probably damaging	1.00
IGL03288:Dnah8	APN	17	30,672,349 (GRCm38)	missense	probably benign
IGL03348:Dnah8	APN	17	30,746,986 (GRCm38)	missense	probably damaging	0.99
Alternator	UTSW	17	30,765,635 (GRCm38)	missense	probably benign
armature	UTSW	17	30,708,390 (GRCm38)	missense	probably benign	0.02
Brush	UTSW	17	30,746,990 (GRCm38)	missense	probably damaging	1.00
Dynos	UTSW	17	30,715,509 (GRCm38)	missense	possibly damaging	0.84
joule	UTSW	17	30,713,098 (GRCm38)	critical splice donor site	probably null
solenoid	UTSW	17	30,741,178 (GRCm38)	missense	probably damaging	1.00
FR4340:Dnah8	UTSW	17	30,635,463 (GRCm38)	small deletion	probably benign
FR4737:Dnah8	UTSW	17	30,635,477 (GRCm38)	small deletion	probably benign
FR4737:Dnah8	UTSW	17	30,635,465 (GRCm38)	small deletion	probably benign
I2288:Dnah8	UTSW	17	30,663,454 (GRCm38)	missense	probably benign
P0029:Dnah8	UTSW	17	30,765,720 (GRCm38)	missense	probably damaging	1.00
PIT4812001:Dnah8	UTSW	17	30,708,445 (GRCm38)	missense	probably benign	0.04
R0016:Dnah8	UTSW	17	30,663,316 (GRCm38)	missense	probably benign
R0035:Dnah8	UTSW	17	30,683,621 (GRCm38)	splice site	probably benign
R0035:Dnah8	UTSW	17	30,683,621 (GRCm38)	splice site	probably benign
R0062:Dnah8	UTSW	17	30,765,711 (GRCm38)	missense	probably damaging	1.00
R0062:Dnah8	UTSW	17	30,765,711 (GRCm38)	missense	probably damaging	1.00
R0087:Dnah8	UTSW	17	30,755,119 (GRCm38)	missense	probably damaging	1.00
R0090:Dnah8	UTSW	17	30,784,090 (GRCm38)	missense	probably benign	0.20
R0119:Dnah8	UTSW	17	30,715,509 (GRCm38)	missense	possibly damaging	0.84
R0164:Dnah8	UTSW	17	30,748,665 (GRCm38)	missense	probably benign
R0164:Dnah8	UTSW	17	30,748,665 (GRCm38)	missense	probably benign
R0184:Dnah8	UTSW	17	30,683,683 (GRCm38)	missense	probably benign	0.04
R0240:Dnah8	UTSW	17	30,765,679 (GRCm38)	missense	probably damaging	0.98
R0240:Dnah8	UTSW	17	30,765,679 (GRCm38)	missense	probably damaging	0.98
R0241:Dnah8	UTSW	17	30,765,679 (GRCm38)	missense	probably damaging	0.98
R0241:Dnah8	UTSW	17	30,765,679 (GRCm38)	missense	probably damaging	0.98
R0265:Dnah8	UTSW	17	30,690,271 (GRCm38)	missense	probably benign
R0268:Dnah8	UTSW	17	30,769,707 (GRCm38)	missense	probably damaging	1.00
R0282:Dnah8	UTSW	17	30,736,156 (GRCm38)	missense	probably damaging	1.00
R0299:Dnah8	UTSW	17	30,715,509 (GRCm38)	missense	possibly damaging	0.84
R0334:Dnah8	UTSW	17	30,871,351 (GRCm38)	missense	probably damaging	0.99
R0393:Dnah8	UTSW	17	30,708,390 (GRCm38)	missense	probably benign	0.02
R0423:Dnah8	UTSW	17	30,701,981 (GRCm38)	missense	probably benign
R0470:Dnah8	UTSW	17	30,708,540 (GRCm38)	splice site	probably benign
R0477:Dnah8	UTSW	17	30,755,080 (GRCm38)	missense	probably damaging	1.00
R0490:Dnah8	UTSW	17	30,700,419 (GRCm38)	missense	probably benign
R0499:Dnah8	UTSW	17	30,715,509 (GRCm38)	missense	possibly damaging	0.84
R0582:Dnah8	UTSW	17	30,718,961 (GRCm38)	missense	probably benign	0.01
R0601:Dnah8	UTSW	17	30,708,358 (GRCm38)	missense	probably benign	0.06
R0646:Dnah8	UTSW	17	30,684,173 (GRCm38)	missense	probably damaging	0.97
R0665:Dnah8	UTSW	17	30,736,155 (GRCm38)	missense	probably damaging	0.99
R0800:Dnah8	UTSW	17	30,704,662 (GRCm38)	missense	probably benign
R0843:Dnah8	UTSW	17	30,813,095 (GRCm38)	missense	probably damaging	1.00
R0940:Dnah8	UTSW	17	30,803,243 (GRCm38)	missense	probably damaging	1.00
R0964:Dnah8	UTSW	17	30,673,920 (GRCm38)	splice site	probably null
R1102:Dnah8	UTSW	17	30,854,764 (GRCm38)	splice site	probably null
R1137:Dnah8	UTSW	17	30,855,936 (GRCm38)	missense	probably damaging	1.00
R1342:Dnah8	UTSW	17	30,721,000 (GRCm38)	missense	probably damaging	0.99
R1375:Dnah8	UTSW	17	30,737,295 (GRCm38)	missense	probably damaging	1.00
R1377:Dnah8	UTSW	17	30,840,622 (GRCm38)	nonsense	probably null
R1464:Dnah8	UTSW	17	30,695,173 (GRCm38)	missense	possibly damaging	0.81
R1464:Dnah8	UTSW	17	30,695,173 (GRCm38)	missense	possibly damaging	0.81
R1470:Dnah8	UTSW	17	30,747,277 (GRCm38)	nonsense	probably null
R1470:Dnah8	UTSW	17	30,747,277 (GRCm38)	nonsense	probably null
R1497:Dnah8	UTSW	17	30,752,075 (GRCm38)	missense	probably damaging	1.00
R1513:Dnah8	UTSW	17	30,673,888 (GRCm38)	missense	probably benign
R1541:Dnah8	UTSW	17	30,747,247 (GRCm38)	missense	probably damaging	1.00
R1563:Dnah8	UTSW	17	30,635,664 (GRCm38)	missense	probably benign	0.07
R1634:Dnah8	UTSW	17	30,713,098 (GRCm38)	critical splice donor site	probably null
R1670:Dnah8	UTSW	17	30,725,124 (GRCm38)	missense	probably damaging	1.00
R1710:Dnah8	UTSW	17	30,854,940 (GRCm38)	missense	probably damaging	1.00
R1743:Dnah8	UTSW	17	30,769,651 (GRCm38)	missense	probably benign	0.28
R1761:Dnah8	UTSW	17	30,779,916 (GRCm38)	missense	probably damaging	1.00
R1785:Dnah8	UTSW	17	30,722,937 (GRCm38)	missense	probably damaging	0.98
R1804:Dnah8	UTSW	17	30,708,407 (GRCm38)	missense	probably benign	0.00
R1808:Dnah8	UTSW	17	30,684,186 (GRCm38)	missense	probably damaging	1.00
R1824:Dnah8	UTSW	17	30,731,180 (GRCm38)	missense	possibly damaging	0.67
R1836:Dnah8	UTSW	17	30,874,927 (GRCm38)	missense	possibly damaging	0.94
R1935:Dnah8	UTSW	17	30,635,505 (GRCm38)	missense	unknown
R1935:Dnah8	UTSW	17	30,726,896 (GRCm38)	splice site	probably benign
R1940:Dnah8	UTSW	17	30,731,207 (GRCm38)	missense	probably damaging	1.00
R1946:Dnah8	UTSW	17	30,712,385 (GRCm38)	missense	probably benign	0.00
R2025:Dnah8	UTSW	17	30,731,159 (GRCm38)	missense	probably damaging	0.99
R2038:Dnah8	UTSW	17	30,758,281 (GRCm38)	missense	probably damaging	1.00
R2042:Dnah8	UTSW	17	30,635,658 (GRCm38)	missense	probably benign	0.01
R2148:Dnah8	UTSW	17	30,737,258 (GRCm38)	missense	probably damaging	1.00
R2177:Dnah8	UTSW	17	30,653,393 (GRCm38)	missense	probably benign
R2180:Dnah8	UTSW	17	30,840,647 (GRCm38)	missense	probably benign	0.00
R2262:Dnah8	UTSW	17	30,673,835 (GRCm38)	missense	probably damaging	1.00
R2263:Dnah8	UTSW	17	30,673,835 (GRCm38)	missense	probably damaging	1.00
R2328:Dnah8	UTSW	17	30,794,744 (GRCm38)	missense	probably damaging	1.00
R2357:Dnah8	UTSW	17	30,771,872 (GRCm38)	missense	probably benign
R2357:Dnah8	UTSW	17	30,874,935 (GRCm38)	missense	probably benign	0.00
R2360:Dnah8	UTSW	17	30,677,204 (GRCm38)	missense	probably benign	0.22
R2496:Dnah8	UTSW	17	30,851,731 (GRCm38)	missense	probably damaging	1.00
R2497:Dnah8	UTSW	17	30,741,365 (GRCm38)	nonsense	probably null
R2509:Dnah8	UTSW	17	30,775,045 (GRCm38)	missense	probably benign	0.02
R3114:Dnah8	UTSW	17	30,833,568 (GRCm38)	missense	probably benign	0.04
R3708:Dnah8	UTSW	17	30,739,657 (GRCm38)	missense	probably damaging	0.98
R3720:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3722:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3727:Dnah8	UTSW	17	30,739,648 (GRCm38)	nonsense	probably null
R3747:Dnah8	UTSW	17	30,784,174 (GRCm38)	nonsense	probably null
R3748:Dnah8	UTSW	17	30,784,174 (GRCm38)	nonsense	probably null
R3749:Dnah8	UTSW	17	30,784,174 (GRCm38)	nonsense	probably null
R3787:Dnah8	UTSW	17	30,755,041 (GRCm38)	missense	probably damaging	1.00
R3790:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3804:Dnah8	UTSW	17	30,670,647 (GRCm38)	missense	probably benign	0.00
R3857:Dnah8	UTSW	17	30,663,422 (GRCm38)	missense	probably damaging	0.96
R3898:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3899:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3938:Dnah8	UTSW	17	30,854,937 (GRCm38)	missense	probably damaging	1.00
R3943:Dnah8	UTSW	17	30,694,065 (GRCm38)	splice site	probably benign
R4091:Dnah8	UTSW	17	30,769,839 (GRCm38)	missense	probably damaging	1.00
R4291:Dnah8	UTSW	17	30,748,559 (GRCm38)	missense	probably benign
R4326:Dnah8	UTSW	17	30,752,092 (GRCm38)	missense	probably benign	0.04
R4346:Dnah8	UTSW	17	30,725,098 (GRCm38)	missense	possibly damaging	0.92
R4429:Dnah8	UTSW	17	30,752,146 (GRCm38)	missense	probably damaging	1.00
R4457:Dnah8	UTSW	17	30,813,151 (GRCm38)	missense	probably benign
R4475:Dnah8	UTSW	17	30,656,985 (GRCm38)	missense	probably benign	0.12
R4565:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4566:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4568:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4573:Dnah8	UTSW	17	30,700,406 (GRCm38)	missense	probably benign	0.00
R4580:Dnah8	UTSW	17	30,662,052 (GRCm38)	missense	probably benign	0.00
R4585:Dnah8	UTSW	17	30,751,567 (GRCm38)	missense	probably benign	0.01
R4611:Dnah8	UTSW	17	30,684,237 (GRCm38)	missense	probably damaging	1.00
R4720:Dnah8	UTSW	17	30,683,634 (GRCm38)	missense	probably benign	0.08
R4721:Dnah8	UTSW	17	30,725,166 (GRCm38)	missense	probably damaging	1.00
R4727:Dnah8	UTSW	17	30,851,747 (GRCm38)	missense	probably damaging	1.00
R4731:Dnah8	UTSW	17	30,775,061 (GRCm38)	missense	probably null	0.02
R4732:Dnah8	UTSW	17	30,775,061 (GRCm38)	missense	probably null	0.02
R4733:Dnah8	UTSW	17	30,775,061 (GRCm38)	missense	probably null	0.02
R4798:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4814:Dnah8	UTSW	17	30,767,924 (GRCm38)	missense	probably damaging	1.00
R4892:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4894:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4900:Dnah8	UTSW	17	30,746,975 (GRCm38)	missense	probably damaging	1.00
R4901:Dnah8	UTSW	17	30,840,714 (GRCm38)	critical splice donor site	probably null
R4913:Dnah8	UTSW	17	30,819,139 (GRCm38)	missense	probably damaging	0.99
R4931:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4932:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4942:Dnah8	UTSW	17	30,729,142 (GRCm38)	missense	probably benign
R4969:Dnah8	UTSW	17	30,723,014 (GRCm38)	missense	probably damaging	1.00
R4975:Dnah8	UTSW	17	30,656,985 (GRCm38)	missense	probably benign	0.12
R4977:Dnah8	UTSW	17	30,663,301 (GRCm38)	missense	probably benign	0.00
R5001:Dnah8	UTSW	17	30,787,185 (GRCm38)	missense	probably damaging	1.00
R5011:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5013:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5014:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5024:Dnah8	UTSW	17	30,736,096 (GRCm38)	missense	probably damaging	1.00
R5075:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5075:Dnah8	UTSW	17	30,800,531 (GRCm38)	missense	probably damaging	1.00
R5075:Dnah8	UTSW	17	30,739,757 (GRCm38)	critical splice donor site	probably null
R5112:Dnah8	UTSW	17	30,731,038 (GRCm38)	missense	probably benign	0.02
R5121:Dnah8	UTSW	17	30,810,353 (GRCm38)	missense	probably benign	0.14
R5138:Dnah8	UTSW	17	30,765,597 (GRCm38)	missense	probably damaging	0.99
R5151:Dnah8	UTSW	17	30,712,295 (GRCm38)	missense	probably benign	0.06
R5191:Dnah8	UTSW	17	30,746,765 (GRCm38)	missense	probably damaging	1.00
R5238:Dnah8	UTSW	17	30,790,917 (GRCm38)	missense	probably damaging	1.00
R5260:Dnah8	UTSW	17	30,700,419 (GRCm38)	missense	probably benign
R5358:Dnah8	UTSW	17	30,746,954 (GRCm38)	missense	probably damaging	1.00
R5403:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5404:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5482:Dnah8	UTSW	17	30,800,547 (GRCm38)	missense	probably damaging	0.96
R5489:Dnah8	UTSW	17	30,790,956 (GRCm38)	missense	probably damaging	1.00
R5513:Dnah8	UTSW	17	30,752,916 (GRCm38)	missense	probably damaging	0.99
R5635:Dnah8	UTSW	17	30,706,386 (GRCm38)	missense	probably benign	0.00
R5640:Dnah8	UTSW	17	30,803,108 (GRCm38)	missense	probably damaging	1.00
R5649:Dnah8	UTSW	17	30,800,587 (GRCm38)	missense	probably benign	0.13
R5662:Dnah8	UTSW	17	30,737,333 (GRCm38)	missense	probably damaging	1.00
R5673:Dnah8	UTSW	17	30,803,261 (GRCm38)	missense	probably damaging	1.00
R5677:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5699:Dnah8	UTSW	17	30,810,324 (GRCm38)	missense	probably benign	0.22
R5737:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5738:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5739:Dnah8	UTSW	17	30,719,007 (GRCm38)	missense	probably benign	0.00
R5766:Dnah8	UTSW	17	30,690,261 (GRCm38)	missense	probably benign	0.01
R5790:Dnah8	UTSW	17	30,875,004 (GRCm38)	missense	probably damaging	0.98
R5848:Dnah8	UTSW	17	30,728,191 (GRCm38)	missense	possibly damaging	0.69
R5854:Dnah8	UTSW	17	30,794,763 (GRCm38)	missense	possibly damaging	0.45
R5885:Dnah8	UTSW	17	30,794,717 (GRCm38)	missense	probably damaging	1.00
R5886:Dnah8	UTSW	17	30,794,717 (GRCm38)	missense	probably damaging	1.00
R5887:Dnah8	UTSW	17	30,794,717 (GRCm38)	missense	probably damaging	1.00
R5899:Dnah8	UTSW	17	30,656,685 (GRCm38)	missense	probably benign	0.32
R5979:Dnah8	UTSW	17	30,815,664 (GRCm38)	nonsense	probably null
R5986:Dnah8	UTSW	17	30,851,630 (GRCm38)	missense	possibly damaging	0.83
R5999:Dnah8	UTSW	17	30,663,305 (GRCm38)	missense	probably benign	0.32
R6042:Dnah8	UTSW	17	30,747,265 (GRCm38)	missense	probably damaging	1.00
R6175:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6181:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6237:Dnah8	UTSW	17	30,747,854 (GRCm38)	nonsense	probably null
R6239:Dnah8	UTSW	17	30,810,359 (GRCm38)	missense	probably damaging	0.99
R6337:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6365:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6416:Dnah8	UTSW	17	30,765,635 (GRCm38)	missense	probably benign
R6443:Dnah8	UTSW	17	30,771,885 (GRCm38)	missense	probably benign	0.10
R6478:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6479:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6480:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6481:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6533:Dnah8	UTSW	17	30,746,990 (GRCm38)	missense	probably damaging	1.00
R6606:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6608:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6610:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6675:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6723:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6724:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6754:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6755:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6759:Dnah8	UTSW	17	30,663,292 (GRCm38)	splice site	probably null
R6765:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6766:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6778:Dnah8	UTSW	17	30,635,666 (GRCm38)	missense	probably benign	0.00
R6781:Dnah8	UTSW	17	30,765,724 (GRCm38)	frame shift	probably null
R6788:Dnah8	UTSW	17	30,648,465 (GRCm38)	missense	probably benign	0.14
R6814:Dnah8	UTSW	17	30,762,679 (GRCm38)	missense	probably damaging	1.00
R6825:Dnah8	UTSW	17	30,741,173 (GRCm38)	missense	probably damaging	1.00
R6838:Dnah8	UTSW	17	30,710,551 (GRCm38)	missense	probably damaging	1.00
R6872:Dnah8	UTSW	17	30,762,679 (GRCm38)	missense	probably damaging	1.00
R6877:Dnah8	UTSW	17	30,746,959 (GRCm38)	missense	probably damaging	1.00
R6944:Dnah8	UTSW	17	30,794,659 (GRCm38)	missense	probably benign	0.09
R6982:Dnah8	UTSW	17	30,767,925 (GRCm38)	missense	probably benign	0.03
R6984:Dnah8	UTSW	17	30,739,738 (GRCm38)	missense	probably damaging	1.00
R6987:Dnah8	UTSW	17	30,662,091 (GRCm38)	missense	possibly damaging	0.95
R6988:Dnah8	UTSW	17	30,643,275 (GRCm38)	missense	probably damaging	1.00
R7099:Dnah8	UTSW	17	30,704,724 (GRCm38)	missense	possibly damaging	0.93
R7106:Dnah8	UTSW	17	30,741,178 (GRCm38)	missense	probably damaging	1.00
R7112:Dnah8	UTSW	17	30,871,392 (GRCm38)	missense	possibly damaging	0.79
R7146:Dnah8	UTSW	17	30,769,644 (GRCm38)	missense	possibly damaging	0.90
R7146:Dnah8	UTSW	17	30,644,617 (GRCm38)	missense	probably benign	0.01
R7309:Dnah8	UTSW	17	30,875,014 (GRCm38)	missense	probably damaging	1.00
R7324:Dnah8	UTSW	17	30,784,125 (GRCm38)	missense	probably benign	0.01
R7373:Dnah8	UTSW	17	30,767,965 (GRCm38)	critical splice donor site	probably null
R7423:Dnah8	UTSW	17	30,704,769 (GRCm38)	missense	possibly damaging	0.86
R7430:Dnah8	UTSW	17	30,706,389 (GRCm38)	missense	probably damaging	0.98
R7450:Dnah8	UTSW	17	30,787,191 (GRCm38)	missense	probably damaging	0.99
R7580:Dnah8	UTSW	17	30,775,103 (GRCm38)	missense	probably damaging	0.98
R7604:Dnah8	UTSW	17	30,813,095 (GRCm38)	missense	probably damaging	1.00
R7635:Dnah8	UTSW	17	30,785,107 (GRCm38)	missense	probably damaging	1.00
R7646:Dnah8	UTSW	17	30,649,677 (GRCm38)	missense	probably benign	0.00
R7685:Dnah8	UTSW	17	30,657,973 (GRCm38)	missense	probably damaging	1.00
R7793:Dnah8	UTSW	17	30,855,944 (GRCm38)	missense	probably benign	0.20
R7827:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R7866:Dnah8	UTSW	17	30,874,927 (GRCm38)	missense	possibly damaging	0.94
R7877:Dnah8	UTSW	17	30,663,374 (GRCm38)	missense	probably benign
R7891:Dnah8	UTSW	17	30,712,289 (GRCm38)	missense	probably benign	0.09
R7977:Dnah8	UTSW	17	30,744,524 (GRCm38)	missense	probably damaging	1.00
R7987:Dnah8	UTSW	17	30,744,524 (GRCm38)	missense	probably damaging	1.00
R8025:Dnah8	UTSW	17	30,741,337 (GRCm38)	nonsense	probably null
R8076:Dnah8	UTSW	17	30,784,153 (GRCm38)	missense	possibly damaging	0.94
R8170:Dnah8	UTSW	17	30,673,823 (GRCm38)	missense	probably damaging	1.00
R8199:Dnah8	UTSW	17	30,871,419 (GRCm38)	missense	probably benign	0.06
R8253:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R8270:Dnah8	UTSW	17	30,840,713 (GRCm38)	missense	probably damaging	1.00
R8291:Dnah8	UTSW	17	30,765,727 (GRCm38)	missense	probably damaging	1.00
R8334:Dnah8	UTSW	17	30,769,831 (GRCm38)	missense	probably benign	0.12
R8348:Dnah8	UTSW	17	30,673,840 (GRCm38)	missense	probably benign
R8348:Dnah8	UTSW	17	30,736,147 (GRCm38)	missense	probably damaging	0.96
R8354:Dnah8	UTSW	17	30,643,260 (GRCm38)	missense	probably benign	0.17
R8355:Dnah8	UTSW	17	30,695,178 (GRCm38)	missense	possibly damaging	0.89
R8439:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R8448:Dnah8	UTSW	17	30,673,840 (GRCm38)	missense	probably benign
R8459:Dnah8	UTSW	17	30,725,247 (GRCm38)	critical splice donor site	probably null
R8462:Dnah8	UTSW	17	30,656,629 (GRCm38)	missense	probably damaging	1.00
R8506:Dnah8	UTSW	17	30,721,134 (GRCm38)	missense	probably benign
R8524:Dnah8	UTSW	17	30,715,498 (GRCm38)	missense	possibly damaging	0.95
R8555:Dnah8	UTSW	17	30,721,110 (GRCm38)	nonsense	probably null
R8698:Dnah8	UTSW	17	30,875,035 (GRCm38)	missense	probably damaging	1.00
R8719:Dnah8	UTSW	17	30,741,315 (GRCm38)	missense	probably damaging	0.97
R8778:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R8781:Dnah8	UTSW	17	30,725,104 (GRCm38)	missense	probably damaging	1.00
R8821:Dnah8	UTSW	17	30,794,738 (GRCm38)	missense	probably damaging	1.00
R8864:Dnah8	UTSW	17	30,762,642 (GRCm38)	missense	possibly damaging	0.95
R8885:Dnah8	UTSW	17	30,708,312 (GRCm38)	missense	possibly damaging	0.83
R8983:Dnah8	UTSW	17	30,851,654 (GRCm38)	missense	probably damaging	0.98
R8994:Dnah8	UTSW	17	30,790,833 (GRCm38)	missense	probably benign	0.05
R9031:Dnah8	UTSW	17	30,737,427 (GRCm38)	missense	probably damaging	1.00
R9068:Dnah8	UTSW	17	30,756,755 (GRCm38)	missense	possibly damaging	0.63
R9225:Dnah8	UTSW	17	30,635,673 (GRCm38)	missense	probably benign	0.01
R9280:Dnah8	UTSW	17	30,785,097 (GRCm38)	missense	possibly damaging	0.52
R9291:Dnah8	UTSW	17	30,725,125 (GRCm38)	missense	probably damaging	1.00
R9314:Dnah8	UTSW	17	30,771,883 (GRCm38)	missense	probably benign
R9347:Dnah8	UTSW	17	30,708,359 (GRCm38)	missense	probably benign	0.00
R9393:Dnah8	UTSW	17	30,653,387 (GRCm38)	missense	possibly damaging	0.53
R9415:Dnah8	UTSW	17	30,810,323 (GRCm38)	missense	probably benign	0.02
R9458:Dnah8	UTSW	17	30,830,803 (GRCm38)	missense	probably damaging	1.00
R9465:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9518:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9524:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9564:Dnah8	UTSW	17	30,713,047 (GRCm38)	missense	probably benign	0.07
R9587:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9599:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9641:Dnah8	UTSW	17	30,713,055 (GRCm38)	missense	probably benign	0.13
R9674:Dnah8	UTSW	17	30,779,138 (GRCm38)	missense	possibly damaging	0.84
R9679:Dnah8	UTSW	17	30,818,141 (GRCm38)	missense	probably benign
R9789:Dnah8	UTSW	17	30,761,130 (GRCm38)	critical splice donor site	probably null
RF027:Dnah8	UTSW	17	30,635,476 (GRCm38)	frame shift	probably null
X0001:Dnah8	UTSW	17	30,748,680 (GRCm38)	missense	probably damaging	1.00
X0013:Dnah8	UTSW	17	30,819,186 (GRCm38)	missense	possibly damaging	0.71
Z1176:Dnah8	UTSW	17	30,648,540 (GRCm38)	missense	probably benign
Z1177:Dnah8	UTSW	17	30,713,095 (GRCm38)	missense	probably null	1.00
Z1177:Dnah8	UTSW	17	30,694,033 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GGACACTCATCAGGCTATGTC -3'
(R):5'- TTAGCCGCACTTACCGTAGTC -3'

Sequencing Primer
(F):5'- GACACTCATCAGGCTATGTCTTGAG -3'
(R):5'- TACATAGTCTGCTGGGAG -3'

Posted On

2016-04-15