Incidental Mutation 'R4934:Clca3a2'
| ID |
380783 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clca3a2
|
| Ensembl Gene |
ENSMUSG00000028262 |
| Gene Name |
chloride channel accessory 3A2 |
| Synonyms |
Clca2 |
| MMRRC Submission |
042534-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.089)
|
| Stock # |
R4934 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
144502320-144525255 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 144523692 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Histidine
at position 98
(Y98H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000029929
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029929]
[ENSMUST00000159989]
|
| AlphaFold |
Q9EQR4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000029929
AA Change: Y98H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000029929
Gene: ENSMUSG00000028262
AA Change: Y98H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
VWA
|
306 |
478 |
1.5e-21 |
SMART |
|
FN3
|
758 |
857 |
5.49e0 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159643
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159989
|
| SMART Domains |
Protein: ENSMUSP00000124581
Gene: ENSMUSG00000037033
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
VWA
|
306 |
481 |
6.22e-19 |
SMART |
|
FN3
|
762 |
861 |
4.93e0 |
SMART |
|
low complexity region
|
880 |
1025 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000198543
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.0%
- 20x: 91.4%
|
| Validation Efficiency |
99% (134/135) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 125 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931428L18Rik |
A |
T |
1: 31,261,580 (GRCm39) |
|
probably benign |
Het |
| Acy1 |
T |
A |
9: 106,312,321 (GRCm39) |
I14F |
probably null |
Het |
| Ago1 |
T |
C |
4: 126,342,652 (GRCm39) |
D193G |
possibly damaging |
Het |
| Arhgap45 |
A |
T |
10: 79,856,791 (GRCm39) |
H201L |
probably damaging |
Het |
| Armc9 |
G |
A |
1: 86,140,801 (GRCm39) |
D63N |
probably damaging |
Het |
| Asb17 |
A |
T |
3: 153,556,336 (GRCm39) |
I148F |
possibly damaging |
Het |
| Atf7ip2 |
A |
G |
16: 10,059,447 (GRCm39) |
E329G |
possibly damaging |
Het |
| Atp2a1 |
T |
A |
7: 126,052,600 (GRCm39) |
D373V |
probably benign |
Het |
| Cacna1e |
G |
T |
1: 154,357,380 (GRCm39) |
Y603* |
probably null |
Het |
| Cbln4 |
G |
A |
2: 171,880,901 (GRCm39) |
T131I |
probably damaging |
Het |
| Ccdc126 |
A |
G |
6: 49,311,181 (GRCm39) |
E63G |
probably damaging |
Het |
| Ccl4 |
T |
A |
11: 83,553,504 (GRCm39) |
S6T |
unknown |
Het |
| Ccnb1 |
A |
T |
13: 100,918,209 (GRCm39) |
I146K |
possibly damaging |
Het |
| Ccr8 |
T |
A |
9: 119,923,815 (GRCm39) |
M310K |
probably benign |
Het |
| Cd180 |
A |
T |
13: 102,875,672 (GRCm39) |
|
probably null |
Het |
| Cd46 |
G |
C |
1: 194,765,107 (GRCm39) |
|
probably benign |
Het |
| Cebpb |
A |
G |
2: 167,531,005 (GRCm39) |
M22V |
probably benign |
Het |
| Cep152 |
A |
G |
2: 125,453,016 (GRCm39) |
I352T |
possibly damaging |
Het |
| Cep295 |
T |
G |
9: 15,244,456 (GRCm39) |
E1333D |
probably damaging |
Het |
| Ces4a |
A |
G |
8: 105,864,613 (GRCm39) |
H30R |
probably benign |
Het |
| Chrm3 |
A |
G |
13: 9,927,450 (GRCm39) |
Y529H |
probably damaging |
Het |
| Chrnb4 |
T |
C |
9: 54,942,101 (GRCm39) |
Y391C |
probably benign |
Het |
| Clvs1 |
C |
T |
4: 9,424,216 (GRCm39) |
H221Y |
possibly damaging |
Het |
| Col3a1 |
G |
A |
1: 45,379,112 (GRCm39) |
|
probably benign |
Het |
| Cpn2 |
T |
G |
16: 30,079,344 (GRCm39) |
N119T |
probably damaging |
Het |
| Cspg4b |
C |
A |
13: 113,504,882 (GRCm39) |
Q2004K |
probably damaging |
Het |
| Cubn |
T |
A |
2: 13,494,721 (GRCm39) |
Q109H |
probably benign |
Het |
| Cyp26b1 |
A |
G |
6: 84,553,954 (GRCm39) |
V221A |
possibly damaging |
Het |
| Cyp2e1 |
T |
G |
7: 140,350,030 (GRCm39) |
N238K |
probably damaging |
Het |
| Dst |
C |
T |
1: 34,247,669 (GRCm39) |
A1693V |
probably damaging |
Het |
| Dync2li1 |
A |
G |
17: 84,956,683 (GRCm39) |
Q281R |
probably benign |
Het |
| Enpp2 |
C |
T |
15: 54,745,543 (GRCm39) |
G318S |
probably damaging |
Het |
| Entrep1 |
T |
C |
19: 23,950,789 (GRCm39) |
*597W |
probably null |
Het |
| F13a1 |
G |
T |
13: 37,061,736 (GRCm39) |
P676T |
probably benign |
Het |
| Fam227a |
T |
C |
15: 79,521,262 (GRCm39) |
H267R |
possibly damaging |
Het |
| Fam78a |
G |
A |
2: 31,959,427 (GRCm39) |
R228C |
probably damaging |
Het |
| Fbxw25 |
T |
C |
9: 109,480,705 (GRCm39) |
N325S |
possibly damaging |
Het |
| Foxred1 |
T |
C |
9: 35,121,210 (GRCm39) |
|
probably benign |
Het |
| Fstl5 |
T |
A |
3: 76,496,272 (GRCm39) |
V345E |
probably damaging |
Het |
| Fzd8 |
GAAAAACTCA |
GA |
18: 9,214,492 (GRCm39) |
|
probably null |
Het |
| Hand1 |
T |
C |
11: 57,722,078 (GRCm39) |
R179G |
possibly damaging |
Het |
| Hk1 |
G |
T |
10: 62,194,165 (GRCm39) |
|
probably benign |
Het |
| Hmcn1 |
A |
C |
1: 150,598,286 (GRCm39) |
L1672R |
probably damaging |
Het |
| Hps5 |
G |
A |
7: 46,418,775 (GRCm39) |
Q297* |
probably null |
Het |
| Iars1 |
T |
A |
13: 49,871,460 (GRCm39) |
F699I |
probably benign |
Het |
| Ift140 |
G |
A |
17: 25,267,462 (GRCm39) |
G620E |
probably benign |
Het |
| Igkv4-80 |
A |
C |
6: 68,993,649 (GRCm39) |
S81A |
probably benign |
Het |
| Inpp4a |
T |
G |
1: 37,426,922 (GRCm39) |
Y628D |
possibly damaging |
Het |
| Itk |
C |
T |
11: 46,280,152 (GRCm39) |
R29H |
probably damaging |
Het |
| Kcnv1 |
A |
G |
15: 44,972,644 (GRCm39) |
F413S |
probably damaging |
Het |
| Klhl3 |
A |
T |
13: 58,250,231 (GRCm39) |
Y4* |
probably null |
Het |
| Lonrf1 |
C |
A |
8: 36,701,103 (GRCm39) |
C369F |
probably damaging |
Het |
| Magohb |
A |
T |
6: 131,261,558 (GRCm39) |
|
probably benign |
Het |
| Map3k4 |
G |
A |
17: 12,490,787 (GRCm39) |
R215C |
probably damaging |
Het |
| Map3k8 |
A |
T |
18: 4,339,548 (GRCm39) |
S274R |
possibly damaging |
Het |
| Masp1 |
T |
G |
16: 23,283,826 (GRCm39) |
M470L |
probably damaging |
Het |
| Mfng |
C |
T |
15: 78,648,588 (GRCm39) |
R163H |
probably benign |
Het |
| Muc4 |
A |
T |
16: 32,576,472 (GRCm39) |
|
probably benign |
Het |
| Myo1c |
T |
A |
11: 75,562,676 (GRCm39) |
V981E |
probably damaging |
Het |
| Nedd9 |
A |
T |
13: 41,492,411 (GRCm39) |
I27K |
probably damaging |
Het |
| Nkd2 |
C |
A |
13: 73,970,841 (GRCm39) |
G247V |
probably damaging |
Het |
| Nucb2 |
A |
C |
7: 116,139,199 (GRCm39) |
Q398P |
possibly damaging |
Het |
| Numa1 |
T |
A |
7: 101,660,064 (GRCm39) |
D376E |
probably benign |
Het |
| Or2w1 |
G |
A |
13: 21,317,241 (GRCm39) |
V99I |
probably benign |
Het |
| Or4c101 |
C |
T |
2: 88,389,930 (GRCm39) |
T39I |
probably benign |
Het |
| Or4n5 |
T |
C |
14: 50,133,206 (GRCm39) |
T18A |
probably benign |
Het |
| Or4p23 |
A |
T |
2: 88,576,398 (GRCm39) |
L278* |
probably null |
Het |
| Or4q3 |
C |
T |
14: 50,583,345 (GRCm39) |
V185M |
probably damaging |
Het |
| Or5b119 |
G |
A |
19: 13,456,956 (GRCm39) |
T202I |
possibly damaging |
Het |
| Or6c76b |
A |
T |
10: 129,692,896 (GRCm39) |
N170Y |
possibly damaging |
Het |
| Or8d23 |
A |
T |
9: 38,842,129 (GRCm39) |
I221F |
probably damaging |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Pamr1 |
C |
T |
2: 102,472,549 (GRCm39) |
T616I |
probably benign |
Het |
| Pcnx1 |
G |
A |
12: 82,038,599 (GRCm39) |
V1955I |
possibly damaging |
Het |
| Pira13 |
A |
G |
7: 3,825,676 (GRCm39) |
Y398H |
probably damaging |
Het |
| Plekha3 |
T |
A |
2: 76,510,571 (GRCm39) |
D35E |
possibly damaging |
Het |
| Pnpla2 |
T |
G |
7: 141,038,085 (GRCm39) |
N184K |
probably damaging |
Het |
| Polr3a |
C |
T |
14: 24,502,692 (GRCm39) |
E1216K |
probably benign |
Het |
| Ppp1r21 |
A |
T |
17: 88,852,803 (GRCm39) |
S61C |
probably damaging |
Het |
| Ppp1r21 |
G |
C |
17: 88,852,804 (GRCm39) |
S61T |
probably damaging |
Het |
| Prdm13 |
G |
T |
4: 21,678,223 (GRCm39) |
|
probably benign |
Het |
| Prss53 |
T |
C |
7: 127,487,879 (GRCm39) |
N201S |
probably benign |
Het |
| Rab11fip2 |
A |
G |
19: 59,924,290 (GRCm39) |
L338S |
probably damaging |
Het |
| Rad50 |
T |
C |
11: 53,575,102 (GRCm39) |
N546S |
probably benign |
Het |
| Ralgapa1 |
T |
C |
12: 55,809,359 (GRCm39) |
D472G |
possibly damaging |
Het |
| Rexo4 |
A |
G |
2: 26,850,346 (GRCm39) |
I277T |
probably damaging |
Het |
| Rimbp2 |
C |
T |
5: 128,865,579 (GRCm39) |
V590I |
probably benign |
Het |
| Ripor3 |
A |
G |
2: 167,824,736 (GRCm39) |
V864A |
probably benign |
Het |
| Rnpc3 |
G |
A |
3: 113,418,628 (GRCm39) |
H107Y |
possibly damaging |
Het |
| Ryr1 |
A |
T |
7: 28,767,520 (GRCm39) |
D2927E |
probably damaging |
Het |
| Samd9l |
G |
A |
6: 3,375,621 (GRCm39) |
Q547* |
probably null |
Het |
| Scaper |
T |
C |
9: 55,716,459 (GRCm39) |
E724G |
probably damaging |
Het |
| Secisbp2l |
C |
T |
2: 125,582,409 (GRCm39) |
V1016I |
probably damaging |
Het |
| Selenoo |
T |
A |
15: 88,982,970 (GRCm39) |
M499K |
probably damaging |
Het |
| Sema4a |
T |
A |
3: 88,345,568 (GRCm39) |
D505V |
probably damaging |
Het |
| Sema5a |
T |
C |
15: 32,679,310 (GRCm39) |
M863T |
probably damaging |
Het |
| Slc24a5 |
T |
C |
2: 124,929,940 (GRCm39) |
C414R |
probably damaging |
Het |
| Slc34a2 |
A |
G |
5: 53,224,942 (GRCm39) |
D361G |
probably damaging |
Het |
| Slc5a1 |
T |
C |
5: 33,261,858 (GRCm39) |
Y20H |
probably benign |
Het |
| Slx4ip |
A |
T |
2: 136,910,267 (GRCm39) |
|
probably benign |
Het |
| Snx14 |
T |
A |
9: 88,280,341 (GRCm39) |
E538V |
probably damaging |
Het |
| Sspo |
C |
A |
6: 48,442,486 (GRCm39) |
L1994I |
probably damaging |
Het |
| St13 |
G |
C |
15: 81,283,786 (GRCm39) |
R4G |
probably benign |
Het |
| Stap2 |
A |
G |
17: 56,304,901 (GRCm39) |
S294P |
possibly damaging |
Het |
| Stat1 |
C |
A |
1: 52,193,082 (GRCm39) |
Y651* |
probably null |
Het |
| Syne2 |
A |
G |
12: 75,946,046 (GRCm39) |
T373A |
probably benign |
Het |
| Tacc2 |
A |
G |
7: 130,330,318 (GRCm39) |
S201G |
probably damaging |
Het |
| Tdpoz3 |
G |
A |
3: 93,734,287 (GRCm39) |
E321K |
probably benign |
Het |
| Thumpd1 |
T |
C |
7: 119,316,002 (GRCm39) |
T316A |
probably benign |
Het |
| Tlr3 |
A |
T |
8: 45,850,072 (GRCm39) |
C866S |
probably benign |
Het |
| Tmprss11g |
T |
A |
5: 86,644,401 (GRCm39) |
I148F |
probably benign |
Het |
| Topbp1 |
T |
A |
9: 103,205,568 (GRCm39) |
|
probably benign |
Het |
| Tpm1 |
T |
C |
9: 66,935,331 (GRCm39) |
|
probably null |
Het |
| Traf3ip2 |
T |
A |
10: 39,502,096 (GRCm39) |
S81R |
probably damaging |
Het |
| Trim29 |
T |
A |
9: 43,222,265 (GRCm39) |
N31K |
probably benign |
Het |
| Ubn2 |
C |
T |
6: 38,467,433 (GRCm39) |
P563S |
probably benign |
Het |
| Usp24 |
T |
C |
4: 106,283,743 (GRCm39) |
Y2418H |
probably benign |
Het |
| Vmn2r6 |
T |
A |
3: 64,463,766 (GRCm39) |
D267V |
probably damaging |
Het |
| Wapl |
T |
A |
14: 34,414,052 (GRCm39) |
C305S |
probably benign |
Het |
| Yme1l1 |
C |
A |
2: 23,058,333 (GRCm39) |
S155* |
probably null |
Het |
| Ythdf3 |
T |
A |
3: 16,258,220 (GRCm39) |
H126Q |
probably damaging |
Het |
| Zbtb32 |
A |
T |
7: 30,290,678 (GRCm39) |
C206S |
possibly damaging |
Het |
| Zbtb47 |
T |
C |
9: 121,593,045 (GRCm39) |
V455A |
probably damaging |
Het |
| Zfp518a |
A |
T |
19: 40,902,707 (GRCm39) |
I879F |
probably benign |
Het |
| Zfp938 |
A |
T |
10: 82,062,012 (GRCm39) |
Y203N |
possibly damaging |
Het |
|
| Other mutations in Clca3a2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00419:Clca3a2
|
APN |
3 |
144,804,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01019:Clca3a2
|
APN |
3 |
144,519,388 (GRCm39) |
nonsense |
probably null |
|
|
IGL01337:Clca3a2
|
APN |
3 |
144,800,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01389:Clca3a2
|
APN |
3 |
144,783,629 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01595:Clca3a2
|
APN |
3 |
144,793,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01663:Clca3a2
|
APN |
3 |
144,522,916 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01704:Clca3a2
|
APN |
3 |
144,800,979 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01779:Clca3a2
|
APN |
3 |
144,525,139 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02066:Clca3a2
|
APN |
3 |
144,519,216 (GRCm39) |
missense |
probably benign |
|
|
IGL02301:Clca3a2
|
APN |
3 |
144,512,133 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02416:Clca3a2
|
APN |
3 |
144,790,777 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02455:Clca3a2
|
APN |
3 |
144,787,172 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02481:Clca3a2
|
APN |
3 |
144,790,701 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02526:Clca3a2
|
APN |
3 |
144,793,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02619:Clca3a2
|
APN |
3 |
144,512,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02797:Clca3a2
|
APN |
3 |
144,787,024 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02852:Clca3a2
|
APN |
3 |
144,512,104 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02901:Clca3a2
|
APN |
3 |
144,522,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03162:Clca3a2
|
APN |
3 |
144,512,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03253:Clca3a2
|
APN |
3 |
144,777,324 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL03256:Clca3a2
|
APN |
3 |
144,792,153 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL03294:Clca3a2
|
APN |
3 |
144,803,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3370:Clca3a2
|
UTSW |
3 |
144,783,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0032:Clca3a2
|
UTSW |
3 |
144,522,494 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0244:Clca3a2
|
UTSW |
3 |
144,519,659 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0479:Clca3a2
|
UTSW |
3 |
144,796,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Clca3a2
|
UTSW |
3 |
144,781,571 (GRCm39) |
splice site |
probably benign |
|
|
R0629:Clca3a2
|
UTSW |
3 |
144,778,000 (GRCm39) |
missense |
probably benign |
|
|
R1249:Clca3a2
|
UTSW |
3 |
144,508,765 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1370:Clca3a2
|
UTSW |
3 |
144,519,624 (GRCm39) |
splice site |
probably benign |
|
|
R1488:Clca3a2
|
UTSW |
3 |
144,789,925 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1523:Clca3a2
|
UTSW |
3 |
144,777,405 (GRCm39) |
nonsense |
probably null |
|
|
R1568:Clca3a2
|
UTSW |
3 |
144,781,410 (GRCm39) |
nonsense |
probably null |
|
|
R1586:Clca3a2
|
UTSW |
3 |
144,516,477 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1650:Clca3a2
|
UTSW |
3 |
144,797,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1771:Clca3a2
|
UTSW |
3 |
144,787,171 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1776:Clca3a2
|
UTSW |
3 |
144,519,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1797:Clca3a2
|
UTSW |
3 |
144,503,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1869:Clca3a2
|
UTSW |
3 |
144,512,164 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1871:Clca3a2
|
UTSW |
3 |
144,503,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1919:Clca3a2
|
UTSW |
3 |
144,516,457 (GRCm39) |
missense |
probably benign |
|
|
R1923:Clca3a2
|
UTSW |
3 |
144,511,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:Clca3a2
|
UTSW |
3 |
144,783,699 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2200:Clca3a2
|
UTSW |
3 |
144,519,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2242:Clca3a2
|
UTSW |
3 |
144,796,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2324:Clca3a2
|
UTSW |
3 |
144,512,041 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2937:Clca3a2
|
UTSW |
3 |
144,519,679 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3429:Clca3a2
|
UTSW |
3 |
144,512,088 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3434:Clca3a2
|
UTSW |
3 |
144,514,522 (GRCm39) |
unclassified |
probably benign |
|
|
R3551:Clca3a2
|
UTSW |
3 |
144,508,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3751:Clca3a2
|
UTSW |
3 |
144,777,216 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3952:Clca3a2
|
UTSW |
3 |
144,508,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4120:Clca3a2
|
UTSW |
3 |
144,516,613 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4383:Clca3a2
|
UTSW |
3 |
144,512,081 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4496:Clca3a2
|
UTSW |
3 |
144,797,926 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4518:Clca3a2
|
UTSW |
3 |
144,514,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4598:Clca3a2
|
UTSW |
3 |
144,511,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Clca3a2
|
UTSW |
3 |
144,513,112 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4802:Clca3a2
|
UTSW |
3 |
144,513,112 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4816:Clca3a2
|
UTSW |
3 |
144,516,613 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4942:Clca3a2
|
UTSW |
3 |
144,512,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4962:Clca3a2
|
UTSW |
3 |
144,783,640 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5123:Clca3a2
|
UTSW |
3 |
144,512,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Clca3a2
|
UTSW |
3 |
144,511,599 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5275:Clca3a2
|
UTSW |
3 |
144,519,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5344:Clca3a2
|
UTSW |
3 |
144,793,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5372:Clca3a2
|
UTSW |
3 |
144,503,286 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Clca3a2
|
UTSW |
3 |
144,789,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5656:Clca3a2
|
UTSW |
3 |
144,503,393 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5931:Clca3a2
|
UTSW |
3 |
144,797,886 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6059:Clca3a2
|
UTSW |
3 |
144,516,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6155:Clca3a2
|
UTSW |
3 |
144,525,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6181:Clca3a2
|
UTSW |
3 |
144,796,469 (GRCm39) |
nonsense |
probably null |
|
|
R6254:Clca3a2
|
UTSW |
3 |
144,507,895 (GRCm39) |
missense |
probably benign |
|
|
R6336:Clca3a2
|
UTSW |
3 |
144,512,239 (GRCm39) |
missense |
probably benign |
|
|
R6470:Clca3a2
|
UTSW |
3 |
144,510,024 (GRCm39) |
splice site |
probably null |
|
|
R6593:Clca3a2
|
UTSW |
3 |
144,514,338 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6598:Clca3a2
|
UTSW |
3 |
144,792,246 (GRCm39) |
nonsense |
probably null |
|
|
R6631:Clca3a2
|
UTSW |
3 |
144,519,405 (GRCm39) |
missense |
probably benign |
|
|
R6826:Clca3a2
|
UTSW |
3 |
144,523,815 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6836:Clca3a2
|
UTSW |
3 |
144,512,144 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6896:Clca3a2
|
UTSW |
3 |
144,514,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Clca3a2
|
UTSW |
3 |
144,803,545 (GRCm39) |
missense |
probably benign |
0.40 |
|
R7211:Clca3a2
|
UTSW |
3 |
144,519,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7229:Clca3a2
|
UTSW |
3 |
144,789,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7256:Clca3a2
|
UTSW |
3 |
144,796,608 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7324:Clca3a2
|
UTSW |
3 |
144,514,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7365:Clca3a2
|
UTSW |
3 |
144,804,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7411:Clca3a2
|
UTSW |
3 |
144,507,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7486:Clca3a2
|
UTSW |
3 |
144,503,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7491:Clca3a2
|
UTSW |
3 |
144,519,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7521:Clca3a2
|
UTSW |
3 |
144,507,674 (GRCm39) |
makesense |
probably null |
|
|
R7813:Clca3a2
|
UTSW |
3 |
144,790,726 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7889:Clca3a2
|
UTSW |
3 |
144,516,574 (GRCm39) |
nonsense |
probably null |
|
|
R7946:Clca3a2
|
UTSW |
3 |
144,513,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7991:Clca3a2
|
UTSW |
3 |
144,519,756 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8022:Clca3a2
|
UTSW |
3 |
144,511,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8077:Clca3a2
|
UTSW |
3 |
144,777,288 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8169:Clca3a2
|
UTSW |
3 |
144,783,653 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Clca3a2
|
UTSW |
3 |
144,793,719 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8300:Clca3a2
|
UTSW |
3 |
144,804,692 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8344:Clca3a2
|
UTSW |
3 |
144,511,703 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8350:Clca3a2
|
UTSW |
3 |
144,783,668 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8367:Clca3a2
|
UTSW |
3 |
144,523,508 (GRCm39) |
splice site |
probably null |
|
|
R8371:Clca3a2
|
UTSW |
3 |
144,513,114 (GRCm39) |
nonsense |
probably null |
|
|
R8814:Clca3a2
|
UTSW |
3 |
144,503,525 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8854:Clca3a2
|
UTSW |
3 |
144,783,852 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8876:Clca3a2
|
UTSW |
3 |
144,777,360 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8887:Clca3a2
|
UTSW |
3 |
144,790,810 (GRCm39) |
nonsense |
probably null |
|
|
R9006:Clca3a2
|
UTSW |
3 |
144,783,789 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9031:Clca3a2
|
UTSW |
3 |
144,511,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9069:Clca3a2
|
UTSW |
3 |
144,519,447 (GRCm39) |
splice site |
probably benign |
|
|
R9093:Clca3a2
|
UTSW |
3 |
144,781,481 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9190:Clca3a2
|
UTSW |
3 |
144,796,599 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9201:Clca3a2
|
UTSW |
3 |
144,519,684 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9209:Clca3a2
|
UTSW |
3 |
144,778,005 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9261:Clca3a2
|
UTSW |
3 |
144,525,158 (GRCm39) |
missense |
probably benign |
|
|
R9469:Clca3a2
|
UTSW |
3 |
144,507,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9501:Clca3a2
|
UTSW |
3 |
144,777,322 (GRCm39) |
nonsense |
probably null |
|
|
R9515:Clca3a2
|
UTSW |
3 |
144,508,808 (GRCm39) |
nonsense |
probably null |
|
|
R9569:Clca3a2
|
UTSW |
3 |
144,513,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9664:Clca3a2
|
UTSW |
3 |
144,503,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0025:Clca3a2
|
UTSW |
3 |
144,792,265 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Clca3a2
|
UTSW |
3 |
144,792,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACAAGGACTGTCTCACTTAAGTG -3'
(R):5'- TCGAGATTGCTACCACAATGC -3'
Sequencing Primer
(F):5'- TGTTTGTAACCCCACTGGAGAAG -3'
(R):5'- GAGATTGCTACCACAATGCACTTTTC -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation