Mutagenetix > Incidental Mutation

Incidental Mutation 'R4934:Rimbp2'

380792

Institutional Source

Beutler Lab

Gene Symbol

Rimbp2

Ensembl Gene

ENSMUSG00000029420

Gene Name

RIMS binding protein 2

Synonyms

A930033C01Rik

MMRRC Submission

042534-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4934 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

128834855-129030550 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 128865579 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Isoleucine at position 590 (V590I)

Ref Sequence

ENSEMBL: ENSMUSP00000143725 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000111346] [ENSMUST00000196085] [ENSMUST00000198941] [ENSMUST00000199537] [ENSMUST00000200470]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000111346
AA Change: V590I

PolyPhen 2 Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000106978
Gene: ENSMUSG00000029420
AA Change: V590I

Domain	Start	End	E-Value	Type
coiled coil region	1	84	N/A	INTRINSIC
low complexity region	178	187	N/A	INTRINSIC
SH3	191	254	1.61e-11	SMART
FN3	318	398	1.52e-1	SMART
FN3	412	484	3.59e-3	SMART
FN3	508	594	3.08e-2	SMART
low complexity region	598	624	N/A	INTRINSIC
low complexity region	667	677	N/A	INTRINSIC
low complexity region	774	795	N/A	INTRINSIC
low complexity region	826	842	N/A	INTRINSIC
SH3	878	942	5.24e-11	SMART
SH3	982	1045	7.17e-18	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000196085
AA Change: V590I

PolyPhen 2 Score 0.120 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000143725
Gene: ENSMUSG00000029420
AA Change: V590I

Domain	Start	End	E-Value	Type
coiled coil region	1	84	N/A	INTRINSIC
low complexity region	178	187	N/A	INTRINSIC
SH3	191	254	1e-13	SMART
FN3	318	398	7.7e-4	SMART
FN3	412	484	1.7e-5	SMART
FN3	508	594	1.6e-4	SMART
low complexity region	598	624	N/A	INTRINSIC
low complexity region	667	677	N/A	INTRINSIC
low complexity region	699	720	N/A	INTRINSIC
low complexity region	751	767	N/A	INTRINSIC
SH3	803	867	3.2e-13	SMART
SH3	907	970	4.5e-20	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000198941
AA Change: V590I

PolyPhen 2 Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000142455
Gene: ENSMUSG00000029420
AA Change: V590I

Domain	Start	End	E-Value	Type
coiled coil region	1	84	N/A	INTRINSIC
low complexity region	178	187	N/A	INTRINSIC
SH3	191	254	1.61e-11	SMART
FN3	318	398	1.52e-1	SMART
FN3	412	484	3.59e-3	SMART
FN3	508	594	3.08e-2	SMART
low complexity region	598	624	N/A	INTRINSIC
low complexity region	667	677	N/A	INTRINSIC
low complexity region	774	795	N/A	INTRINSIC
low complexity region	826	842	N/A	INTRINSIC
SH3	878	942	5.24e-11	SMART
SH3	982	1045	7.17e-18	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000199537
AA Change: V583I

PolyPhen 2 Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000143276
Gene: ENSMUSG00000029420
AA Change: V583I

Domain	Start	End	E-Value	Type
coiled coil region	1	77	N/A	INTRINSIC
low complexity region	171	180	N/A	INTRINSIC
SH3	184	247	1.61e-11	SMART
FN3	311	391	1.52e-1	SMART
FN3	405	477	3.59e-3	SMART
FN3	501	587	3.08e-2	SMART
low complexity region	591	617	N/A	INTRINSIC
low complexity region	660	670	N/A	INTRINSIC
low complexity region	767	788	N/A	INTRINSIC
low complexity region	819	835	N/A	INTRINSIC
SH3	871	935	5.24e-11	SMART
SH3	975	1038	7.17e-18	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000200470
AA Change: V583I

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000143099
Gene: ENSMUSG00000029420
AA Change: V583I

Domain	Start	End	E-Value	Type
coiled coil region	1	77	N/A	INTRINSIC
low complexity region	171	180	N/A	INTRINSIC
SH3	184	247	9.8e-14	SMART
FN3	311	391	7.5e-4	SMART
FN3	405	477	1.7e-5	SMART
FN3	501	587	1.5e-4	SMART
low complexity region	591	617	N/A	INTRINSIC
low complexity region	660	670	N/A	INTRINSIC
low complexity region	767	788	N/A	INTRINSIC
low complexity region	819	835	N/A	INTRINSIC
SH3	871	935	3.2e-13	SMART
SH3	975	1038	4.4e-20	SMART

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.0%
20x: 91.4%

Validation Efficiency

99% (134/135)

MGI Phenotype

PHENOTYPE: Homozygous knockout results in a mild neurological phenotype with changes in the synaptic transmission and plasticity of hippocampal neurons. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 125 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4931428L18Rik	A	T	1: 31,261,580 (GRCm39)		probably benign	Het
Acy1	T	A	9: 106,312,321 (GRCm39)	I14F	probably null	Het
Ago1	T	C	4: 126,342,652 (GRCm39)	D193G	possibly damaging	Het
Arhgap45	A	T	10: 79,856,791 (GRCm39)	H201L	probably damaging	Het
Armc9	G	A	1: 86,140,801 (GRCm39)	D63N	probably damaging	Het
Asb17	A	T	3: 153,556,336 (GRCm39)	I148F	possibly damaging	Het
Atf7ip2	A	G	16: 10,059,447 (GRCm39)	E329G	possibly damaging	Het
Atp2a1	T	A	7: 126,052,600 (GRCm39)	D373V	probably benign	Het
Cacna1e	G	T	1: 154,357,380 (GRCm39)	Y603*	probably null	Het
Cbln4	G	A	2: 171,880,901 (GRCm39)	T131I	probably damaging	Het
Ccdc126	A	G	6: 49,311,181 (GRCm39)	E63G	probably damaging	Het
Ccl4	T	A	11: 83,553,504 (GRCm39)	S6T	unknown	Het
Ccnb1	A	T	13: 100,918,209 (GRCm39)	I146K	possibly damaging	Het
Ccr8	T	A	9: 119,923,815 (GRCm39)	M310K	probably benign	Het
Cd180	A	T	13: 102,875,672 (GRCm39)		probably null	Het
Cd46	G	C	1: 194,765,107 (GRCm39)		probably benign	Het
Cebpb	A	G	2: 167,531,005 (GRCm39)	M22V	probably benign	Het
Cep152	A	G	2: 125,453,016 (GRCm39)	I352T	possibly damaging	Het
Cep295	T	G	9: 15,244,456 (GRCm39)	E1333D	probably damaging	Het
Ces4a	A	G	8: 105,864,613 (GRCm39)	H30R	probably benign	Het
Chrm3	A	G	13: 9,927,450 (GRCm39)	Y529H	probably damaging	Het
Chrnb4	T	C	9: 54,942,101 (GRCm39)	Y391C	probably benign	Het
Clca3a2	A	G	3: 144,523,692 (GRCm39)	Y98H	probably damaging	Het
Clvs1	C	T	4: 9,424,216 (GRCm39)	H221Y	possibly damaging	Het
Col3a1	G	A	1: 45,379,112 (GRCm39)		probably benign	Het
Cpn2	T	G	16: 30,079,344 (GRCm39)	N119T	probably damaging	Het
Cspg4b	C	A	13: 113,504,882 (GRCm39)	Q2004K	probably damaging	Het
Cubn	T	A	2: 13,494,721 (GRCm39)	Q109H	probably benign	Het
Cyp26b1	A	G	6: 84,553,954 (GRCm39)	V221A	possibly damaging	Het
Cyp2e1	T	G	7: 140,350,030 (GRCm39)	N238K	probably damaging	Het
Dst	C	T	1: 34,247,669 (GRCm39)	A1693V	probably damaging	Het
Dync2li1	A	G	17: 84,956,683 (GRCm39)	Q281R	probably benign	Het
Enpp2	C	T	15: 54,745,543 (GRCm39)	G318S	probably damaging	Het
Entrep1	T	C	19: 23,950,789 (GRCm39)	*597W	probably null	Het
F13a1	G	T	13: 37,061,736 (GRCm39)	P676T	probably benign	Het
Fam227a	T	C	15: 79,521,262 (GRCm39)	H267R	possibly damaging	Het
Fam78a	G	A	2: 31,959,427 (GRCm39)	R228C	probably damaging	Het
Fbxw25	T	C	9: 109,480,705 (GRCm39)	N325S	possibly damaging	Het
Foxred1	T	C	9: 35,121,210 (GRCm39)		probably benign	Het
Fstl5	T	A	3: 76,496,272 (GRCm39)	V345E	probably damaging	Het
Fzd8	GAAAAACTCA	GA	18: 9,214,492 (GRCm39)		probably null	Het
Hand1	T	C	11: 57,722,078 (GRCm39)	R179G	possibly damaging	Het
Hk1	G	T	10: 62,194,165 (GRCm39)		probably benign	Het
Hmcn1	A	C	1: 150,598,286 (GRCm39)	L1672R	probably damaging	Het
Hps5	G	A	7: 46,418,775 (GRCm39)	Q297*	probably null	Het
Iars1	T	A	13: 49,871,460 (GRCm39)	F699I	probably benign	Het
Ift140	G	A	17: 25,267,462 (GRCm39)	G620E	probably benign	Het
Igkv4-80	A	C	6: 68,993,649 (GRCm39)	S81A	probably benign	Het
Inpp4a	T	G	1: 37,426,922 (GRCm39)	Y628D	possibly damaging	Het
Itk	C	T	11: 46,280,152 (GRCm39)	R29H	probably damaging	Het
Kcnv1	A	G	15: 44,972,644 (GRCm39)	F413S	probably damaging	Het
Klhl3	A	T	13: 58,250,231 (GRCm39)	Y4*	probably null	Het
Lonrf1	C	A	8: 36,701,103 (GRCm39)	C369F	probably damaging	Het
Magohb	A	T	6: 131,261,558 (GRCm39)		probably benign	Het
Map3k4	G	A	17: 12,490,787 (GRCm39)	R215C	probably damaging	Het
Map3k8	A	T	18: 4,339,548 (GRCm39)	S274R	possibly damaging	Het
Masp1	T	G	16: 23,283,826 (GRCm39)	M470L	probably damaging	Het
Mfng	C	T	15: 78,648,588 (GRCm39)	R163H	probably benign	Het
Muc4	A	T	16: 32,576,472 (GRCm39)		probably benign	Het
Myo1c	T	A	11: 75,562,676 (GRCm39)	V981E	probably damaging	Het
Nedd9	A	T	13: 41,492,411 (GRCm39)	I27K	probably damaging	Het
Nkd2	C	A	13: 73,970,841 (GRCm39)	G247V	probably damaging	Het
Nucb2	A	C	7: 116,139,199 (GRCm39)	Q398P	possibly damaging	Het
Numa1	T	A	7: 101,660,064 (GRCm39)	D376E	probably benign	Het
Or2w1	G	A	13: 21,317,241 (GRCm39)	V99I	probably benign	Het
Or4c101	C	T	2: 88,389,930 (GRCm39)	T39I	probably benign	Het
Or4n5	T	C	14: 50,133,206 (GRCm39)	T18A	probably benign	Het
Or4p23	A	T	2: 88,576,398 (GRCm39)	L278*	probably null	Het
Or4q3	C	T	14: 50,583,345 (GRCm39)	V185M	probably damaging	Het
Or5b119	G	A	19: 13,456,956 (GRCm39)	T202I	possibly damaging	Het
Or6c76b	A	T	10: 129,692,896 (GRCm39)	N170Y	possibly damaging	Het
Or8d23	A	T	9: 38,842,129 (GRCm39)	I221F	probably damaging	Het
Otx1	C	A	11: 21,947,037 (GRCm39)	A91S	probably damaging	Het
Pamr1	C	T	2: 102,472,549 (GRCm39)	T616I	probably benign	Het
Pcnx1	G	A	12: 82,038,599 (GRCm39)	V1955I	possibly damaging	Het
Pira13	A	G	7: 3,825,676 (GRCm39)	Y398H	probably damaging	Het
Plekha3	T	A	2: 76,510,571 (GRCm39)	D35E	possibly damaging	Het
Pnpla2	T	G	7: 141,038,085 (GRCm39)	N184K	probably damaging	Het
Polr3a	C	T	14: 24,502,692 (GRCm39)	E1216K	probably benign	Het
Ppp1r21	A	T	17: 88,852,803 (GRCm39)	S61C	probably damaging	Het
Ppp1r21	G	C	17: 88,852,804 (GRCm39)	S61T	probably damaging	Het
Prdm13	G	T	4: 21,678,223 (GRCm39)		probably benign	Het
Prss53	T	C	7: 127,487,879 (GRCm39)	N201S	probably benign	Het
Rab11fip2	A	G	19: 59,924,290 (GRCm39)	L338S	probably damaging	Het
Rad50	T	C	11: 53,575,102 (GRCm39)	N546S	probably benign	Het
Ralgapa1	T	C	12: 55,809,359 (GRCm39)	D472G	possibly damaging	Het
Rexo4	A	G	2: 26,850,346 (GRCm39)	I277T	probably damaging	Het
Ripor3	A	G	2: 167,824,736 (GRCm39)	V864A	probably benign	Het
Rnpc3	G	A	3: 113,418,628 (GRCm39)	H107Y	possibly damaging	Het
Ryr1	A	T	7: 28,767,520 (GRCm39)	D2927E	probably damaging	Het
Samd9l	G	A	6: 3,375,621 (GRCm39)	Q547*	probably null	Het
Scaper	T	C	9: 55,716,459 (GRCm39)	E724G	probably damaging	Het
Secisbp2l	C	T	2: 125,582,409 (GRCm39)	V1016I	probably damaging	Het
Selenoo	T	A	15: 88,982,970 (GRCm39)	M499K	probably damaging	Het
Sema4a	T	A	3: 88,345,568 (GRCm39)	D505V	probably damaging	Het
Sema5a	T	C	15: 32,679,310 (GRCm39)	M863T	probably damaging	Het
Slc24a5	T	C	2: 124,929,940 (GRCm39)	C414R	probably damaging	Het
Slc34a2	A	G	5: 53,224,942 (GRCm39)	D361G	probably damaging	Het
Slc5a1	T	C	5: 33,261,858 (GRCm39)	Y20H	probably benign	Het
Slx4ip	A	T	2: 136,910,267 (GRCm39)		probably benign	Het
Snx14	T	A	9: 88,280,341 (GRCm39)	E538V	probably damaging	Het
Sspo	C	A	6: 48,442,486 (GRCm39)	L1994I	probably damaging	Het
St13	G	C	15: 81,283,786 (GRCm39)	R4G	probably benign	Het
Stap2	A	G	17: 56,304,901 (GRCm39)	S294P	possibly damaging	Het
Stat1	C	A	1: 52,193,082 (GRCm39)	Y651*	probably null	Het
Syne2	A	G	12: 75,946,046 (GRCm39)	T373A	probably benign	Het
Tacc2	A	G	7: 130,330,318 (GRCm39)	S201G	probably damaging	Het
Tdpoz3	G	A	3: 93,734,287 (GRCm39)	E321K	probably benign	Het
Thumpd1	T	C	7: 119,316,002 (GRCm39)	T316A	probably benign	Het
Tlr3	A	T	8: 45,850,072 (GRCm39)	C866S	probably benign	Het
Tmprss11g	T	A	5: 86,644,401 (GRCm39)	I148F	probably benign	Het
Topbp1	T	A	9: 103,205,568 (GRCm39)		probably benign	Het
Tpm1	T	C	9: 66,935,331 (GRCm39)		probably null	Het
Traf3ip2	T	A	10: 39,502,096 (GRCm39)	S81R	probably damaging	Het
Trim29	T	A	9: 43,222,265 (GRCm39)	N31K	probably benign	Het
Ubn2	C	T	6: 38,467,433 (GRCm39)	P563S	probably benign	Het
Usp24	T	C	4: 106,283,743 (GRCm39)	Y2418H	probably benign	Het
Vmn2r6	T	A	3: 64,463,766 (GRCm39)	D267V	probably damaging	Het
Wapl	T	A	14: 34,414,052 (GRCm39)	C305S	probably benign	Het
Yme1l1	C	A	2: 23,058,333 (GRCm39)	S155*	probably null	Het
Ythdf3	T	A	3: 16,258,220 (GRCm39)	H126Q	probably damaging	Het
Zbtb32	A	T	7: 30,290,678 (GRCm39)	C206S	possibly damaging	Het
Zbtb47	T	C	9: 121,593,045 (GRCm39)	V455A	probably damaging	Het
Zfp518a	A	T	19: 40,902,707 (GRCm39)	I879F	probably benign	Het
Zfp938	A	T	10: 82,062,012 (GRCm39)	Y203N	possibly damaging	Het

Other mutations in Rimbp2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00979:Rimbp2	APN	5	128,883,505 (GRCm39)	missense	probably benign	0.00
IGL01321:Rimbp2	APN	5	128,863,816 (GRCm39)	missense	probably benign	0.10
IGL01459:Rimbp2	APN	5	128,865,275 (GRCm39)	critical splice donor site	probably null
IGL01743:Rimbp2	APN	5	128,874,912 (GRCm39)	splice site	probably benign
IGL01975:Rimbp2	APN	5	128,874,712 (GRCm39)	missense	probably benign	0.30
IGL02269:Rimbp2	APN	5	128,851,359 (GRCm39)	missense	probably damaging	1.00
IGL02341:Rimbp2	APN	5	128,878,025 (GRCm39)	nonsense	probably null
IGL02368:Rimbp2	APN	5	128,865,218 (GRCm39)	splice site	probably null
IGL02392:Rimbp2	APN	5	128,848,861 (GRCm39)	missense	probably benign	0.01
IGL03156:Rimbp2	APN	5	128,848,821 (GRCm39)	missense	probably damaging	1.00
IGL02837:Rimbp2	UTSW	5	128,874,809 (GRCm39)	missense	probably damaging	0.98
PIT4418001:Rimbp2	UTSW	5	128,857,425 (GRCm39)	missense	probably benign	0.00
R0193:Rimbp2	UTSW	5	128,865,420 (GRCm39)	missense	probably benign	0.12
R0376:Rimbp2	UTSW	5	128,880,925 (GRCm39)	missense	probably damaging	0.98
R0377:Rimbp2	UTSW	5	128,880,925 (GRCm39)	missense	probably damaging	0.98
R0661:Rimbp2	UTSW	5	128,863,774 (GRCm39)	missense	probably benign	0.20
R1217:Rimbp2	UTSW	5	128,865,351 (GRCm39)	missense	probably benign	0.04
R1376:Rimbp2	UTSW	5	128,847,355 (GRCm39)	missense	possibly damaging	0.75
R1376:Rimbp2	UTSW	5	128,847,355 (GRCm39)	missense	possibly damaging	0.75
R1551:Rimbp2	UTSW	5	128,883,423 (GRCm39)	missense	probably damaging	0.97
R1883:Rimbp2	UTSW	5	128,880,998 (GRCm39)	missense	possibly damaging	0.93
R1970:Rimbp2	UTSW	5	128,874,305 (GRCm39)	missense	probably damaging	1.00
R2111:Rimbp2	UTSW	5	128,850,565 (GRCm39)	missense	probably damaging	1.00
R2120:Rimbp2	UTSW	5	128,865,582 (GRCm39)	missense	probably damaging	1.00
R2155:Rimbp2	UTSW	5	128,865,229 (GRCm39)	missense	probably damaging	0.99
R2332:Rimbp2	UTSW	5	128,866,705 (GRCm39)	missense	probably benign	0.42
R2370:Rimbp2	UTSW	5	128,880,908 (GRCm39)	missense	probably damaging	0.99
R2402:Rimbp2	UTSW	5	128,861,952 (GRCm39)	missense	probably damaging	1.00
R3710:Rimbp2	UTSW	5	128,866,795 (GRCm39)	missense	probably benign	0.16
R3877:Rimbp2	UTSW	5	128,850,529 (GRCm39)	missense	probably damaging	1.00
R3974:Rimbp2	UTSW	5	128,874,862 (GRCm39)	missense	probably damaging	1.00
R4257:Rimbp2	UTSW	5	128,851,324 (GRCm39)	missense	probably damaging	1.00
R4270:Rimbp2	UTSW	5	128,896,841 (GRCm39)	missense	probably benign
R4271:Rimbp2	UTSW	5	128,896,841 (GRCm39)	missense	probably benign
R4281:Rimbp2	UTSW	5	128,865,404 (GRCm39)	missense	possibly damaging	0.82
R5011:Rimbp2	UTSW	5	128,880,985 (GRCm39)	missense	probably damaging	0.98
R5173:Rimbp2	UTSW	5	128,874,712 (GRCm39)	missense	probably benign	0.30
R5288:Rimbp2	UTSW	5	128,865,656 (GRCm39)	missense	probably benign	0.00
R5305:Rimbp2	UTSW	5	128,874,445 (GRCm39)	missense	possibly damaging	0.69
R5554:Rimbp2	UTSW	5	128,857,406 (GRCm39)	missense	probably damaging	0.98
R6189:Rimbp2	UTSW	5	128,880,961 (GRCm39)	missense	probably benign
R7023:Rimbp2	UTSW	5	128,879,847 (GRCm39)	critical splice donor site	probably null
R7096:Rimbp2	UTSW	5	128,851,333 (GRCm39)	missense	probably damaging	0.99
R7451:Rimbp2	UTSW	5	128,865,435 (GRCm39)	missense	probably benign	0.00
R7789:Rimbp2	UTSW	5	128,851,399 (GRCm39)	missense	probably damaging	0.99
R7793:Rimbp2	UTSW	5	128,866,759 (GRCm39)	missense	possibly damaging	0.92
R7894:Rimbp2	UTSW	5	128,838,528 (GRCm39)	missense	probably damaging	1.00
R8300:Rimbp2	UTSW	5	128,874,835 (GRCm39)	missense	probably damaging	1.00
R8377:Rimbp2	UTSW	5	128,857,395 (GRCm39)	missense	probably damaging	1.00
R8894:Rimbp2	UTSW	5	128,850,454 (GRCm39)	missense	possibly damaging	0.78
R9002:Rimbp2	UTSW	5	128,865,356 (GRCm39)	missense	probably benign	0.11
R9075:Rimbp2	UTSW	5	128,851,312 (GRCm39)	missense	probably damaging	1.00
R9198:Rimbp2	UTSW	5	128,883,552 (GRCm39)	missense	probably damaging	0.99
R9709:Rimbp2	UTSW	5	128,874,875 (GRCm39)	missense	probably damaging	1.00
Z1177:Rimbp2	UTSW	5	128,865,244 (GRCm39)	missense	probably damaging	1.00
Z1177:Rimbp2	UTSW	5	128,850,515 (GRCm39)	missense	probably benign	0.01
Z1177:Rimbp2	UTSW	5	128,838,403 (GRCm39)	missense	probably benign	0.07
Z1177:Rimbp2	UTSW	5	128,874,695 (GRCm39)	missense	possibly damaging	0.89
Z1177:Rimbp2	UTSW	5	128,874,671 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TGCATGTCAGGTGGTTCCAAC -3'
(R):5'- CCATGCATCTGCCTTCAAGAG -3'

Sequencing Primer
(F):5'- CATGTCAGGTGGTTCCAACATGTG -3'
(R):5'- CTTCAAGAGATGCCACAGCTGG -3'

Posted On

2016-04-15