Incidental Mutation 'R4928:Abca14'
| ID |
381004 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca14
|
| Ensembl Gene |
ENSMUSG00000062017 |
| Gene Name |
ATP-binding cassette, sub-family A member 14 |
| Synonyms |
1700110B15Rik, 4930539G24Rik |
| MMRRC Submission |
042529-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4928 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
119803184-119924575 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 119923803 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Isoleucine
at position 1620
(N1620I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000081690
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000076272]
[ENSMUST00000084640]
[ENSMUST00000121265]
[ENSMUST00000207220]
|
| AlphaFold |
E9Q8F8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000076272
|
| SMART Domains |
Protein: ENSMUSP00000075621
Gene: ENSMUSG00000054746
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
24 |
464 |
5.7e-21 |
PFAM |
|
AAA
|
550 |
732 |
9.14e-11 |
SMART |
|
Pfam:ABC2_membrane_3
|
892 |
1293 |
7.9e-24 |
PFAM |
|
AAA
|
1381 |
1565 |
1.16e-3 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000084640
AA Change: N1620I
PolyPhen 2
Score 0.896 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000081690
Gene: ENSMUSG00000062017
AA Change: N1620I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
24 |
463 |
5.7e-23 |
PFAM |
|
AAA
|
548 |
729 |
1.59e-10 |
SMART |
|
Pfam:ABC2_membrane_3
|
902 |
1296 |
1.2e-36 |
PFAM |
|
AAA
|
1384 |
1568 |
1.33e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000121265
|
| SMART Domains |
Protein: ENSMUSP00000112821
Gene: ENSMUSG00000054746
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
24 |
464 |
2.1e-21 |
PFAM |
|
AAA
|
550 |
732 |
9.14e-11 |
SMART |
|
Pfam:ABC2_membrane_3
|
907 |
1293 |
1e-25 |
PFAM |
|
AAA
|
1381 |
1565 |
1.16e-3 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140459
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207220
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.5%
|
| Validation Efficiency |
98% (123/126) |
| Allele List at MGI |
All alleles(1) : Gene trapped(1)
|
| Other mutations in this stock |
Total: 110 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A530021J07Rik |
G |
T |
7: 82,805,086 (GRCm39) |
|
noncoding transcript |
Het |
| Aasdh |
T |
A |
5: 77,044,535 (GRCm39) |
K118N |
possibly damaging |
Het |
| Acap1 |
A |
T |
11: 69,776,641 (GRCm39) |
S149T |
possibly damaging |
Het |
| Adgre1 |
T |
A |
17: 57,751,064 (GRCm39) |
Y579* |
probably null |
Het |
| Aifm3 |
T |
C |
16: 17,318,296 (GRCm39) |
|
probably benign |
Het |
| Aldh16a1 |
A |
G |
7: 44,791,385 (GRCm39) |
W107R |
probably damaging |
Het |
| Amer2 |
A |
T |
14: 60,616,894 (GRCm39) |
H363L |
possibly damaging |
Het |
| Arhgap10 |
A |
G |
8: 78,152,957 (GRCm39) |
|
probably null |
Het |
| Arhgef6 |
A |
T |
X: 56,280,238 (GRCm39) |
D742E |
probably damaging |
Het |
| Astn2 |
A |
T |
4: 65,647,644 (GRCm39) |
N731K |
probably damaging |
Het |
| Atp1a2 |
T |
C |
1: 172,105,954 (GRCm39) |
T904A |
possibly damaging |
Het |
| Atr |
C |
T |
9: 95,789,352 (GRCm39) |
R1503W |
probably damaging |
Het |
| Cdh3 |
G |
T |
8: 107,263,242 (GRCm39) |
R97L |
probably benign |
Het |
| Chst2 |
C |
T |
9: 95,288,059 (GRCm39) |
V96I |
probably benign |
Het |
| Cit |
T |
A |
5: 116,123,856 (GRCm39) |
N1464K |
probably benign |
Het |
| Col17a1 |
A |
T |
19: 47,658,897 (GRCm39) |
|
probably null |
Het |
| Col4a3 |
G |
A |
1: 82,688,698 (GRCm39) |
|
probably benign |
Het |
| Copz1 |
T |
A |
15: 103,199,757 (GRCm39) |
S57R |
probably damaging |
Het |
| Cpped1 |
A |
T |
16: 11,646,143 (GRCm39) |
F227Y |
probably damaging |
Het |
| Cyp2j12 |
A |
T |
4: 95,990,388 (GRCm39) |
|
probably null |
Het |
| Dctn1 |
T |
A |
6: 83,166,189 (GRCm39) |
I195N |
possibly damaging |
Het |
| Dhrs7b |
A |
G |
11: 60,742,751 (GRCm39) |
I148V |
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,918,259 (GRCm39) |
D4096G |
probably damaging |
Het |
| Dnajc13 |
T |
C |
9: 104,110,837 (GRCm39) |
N145D |
possibly damaging |
Het |
| Ecpas |
A |
G |
4: 58,827,073 (GRCm39) |
V1020A |
probably damaging |
Het |
| Entrep2 |
G |
T |
7: 64,409,116 (GRCm39) |
S426* |
probably null |
Het |
| Ercc6l2 |
T |
C |
13: 64,042,627 (GRCm39) |
|
probably benign |
Het |
| Fads6 |
T |
G |
11: 115,187,387 (GRCm39) |
I103L |
probably benign |
Het |
| Fat4 |
T |
G |
3: 39,064,614 (GRCm39) |
Y4857D |
probably damaging |
Het |
| Fbxl14 |
T |
A |
6: 119,457,671 (GRCm39) |
L284Q |
probably damaging |
Het |
| Fkbp9 |
T |
C |
6: 56,826,655 (GRCm39) |
V85A |
possibly damaging |
Het |
| Galnt13 |
T |
A |
2: 54,406,577 (GRCm39) |
V9E |
probably damaging |
Het |
| Gm14412 |
A |
T |
2: 177,006,373 (GRCm39) |
S507R |
probably benign |
Het |
| Gm15142 |
T |
A |
X: 153,421,415 (GRCm39) |
|
noncoding transcript |
Het |
| Gm4787 |
T |
C |
12: 81,425,612 (GRCm39) |
E182G |
probably benign |
Het |
| Gm6811 |
C |
A |
17: 21,314,893 (GRCm39) |
|
noncoding transcript |
Het |
| Gm9791 |
A |
T |
3: 34,059,218 (GRCm39) |
|
noncoding transcript |
Het |
| Hoxb7 |
A |
T |
11: 96,180,336 (GRCm39) |
|
probably null |
Het |
| Ift122 |
T |
A |
6: 115,892,819 (GRCm39) |
|
probably benign |
Het |
| Krt28 |
C |
T |
11: 99,265,458 (GRCm39) |
V70I |
probably benign |
Het |
| Lig1 |
T |
C |
7: 13,032,664 (GRCm39) |
S459P |
probably damaging |
Het |
| Lrfn3 |
C |
T |
7: 30,060,048 (GRCm39) |
R59H |
possibly damaging |
Het |
| Mavs |
T |
C |
2: 131,088,663 (GRCm39) |
V489A |
probably benign |
Het |
| Mcm8 |
C |
T |
2: 132,681,399 (GRCm39) |
P625L |
probably benign |
Het |
| Megf10 |
G |
T |
18: 57,373,745 (GRCm39) |
R181L |
probably benign |
Het |
| Mgrn1 |
G |
A |
16: 4,745,726 (GRCm39) |
G440D |
probably benign |
Het |
| Mllt3 |
T |
C |
4: 87,700,642 (GRCm39) |
|
probably null |
Het |
| Muc5ac |
T |
A |
7: 141,371,639 (GRCm39) |
Y2613* |
probably null |
Het |
| Myh14 |
C |
T |
7: 44,284,926 (GRCm39) |
G662S |
probably benign |
Het |
| Myod1 |
T |
A |
7: 46,026,474 (GRCm39) |
N126K |
probably damaging |
Het |
| Nae1 |
A |
T |
8: 105,242,774 (GRCm39) |
H439Q |
possibly damaging |
Het |
| Narf |
T |
A |
11: 121,135,765 (GRCm39) |
V136E |
possibly damaging |
Het |
| Ncapd3 |
T |
A |
9: 26,983,031 (GRCm39) |
C926* |
probably null |
Het |
| Ndufv2 |
C |
A |
17: 66,399,653 (GRCm39) |
|
probably null |
Het |
| Neb |
T |
C |
2: 52,102,987 (GRCm39) |
S449G |
possibly damaging |
Het |
| Nek10 |
C |
T |
14: 14,930,577 (GRCm38) |
P698L |
probably damaging |
Het |
| Nox3 |
T |
A |
17: 3,685,550 (GRCm39) |
E566V |
probably null |
Het |
| Oas1a |
C |
T |
5: 121,043,787 (GRCm39) |
R115H |
probably benign |
Het |
| Or10ag60 |
C |
A |
2: 87,438,487 (GRCm39) |
L252I |
probably benign |
Het |
| Or51b6 |
A |
G |
7: 103,555,879 (GRCm39) |
T78A |
probably damaging |
Het |
| Or5w19 |
A |
G |
2: 87,698,574 (GRCm39) |
M80V |
probably benign |
Het |
| Or8k30 |
T |
A |
2: 86,339,469 (GRCm39) |
L222H |
probably damaging |
Het |
| Pbld2 |
A |
G |
10: 62,883,778 (GRCm39) |
H142R |
probably damaging |
Het |
| Pcdha4 |
C |
T |
18: 37,087,869 (GRCm39) |
T684M |
probably benign |
Het |
| Phc3 |
G |
T |
3: 31,005,068 (GRCm39) |
T175N |
probably damaging |
Het |
| Pigs |
G |
T |
11: 78,219,828 (GRCm39) |
V68L |
probably damaging |
Het |
| Pik3c2g |
T |
A |
6: 139,913,528 (GRCm39) |
D857E |
possibly damaging |
Het |
| Pitpnm3 |
G |
A |
11: 71,953,998 (GRCm39) |
P550S |
probably damaging |
Het |
| Pla2g15 |
G |
A |
8: 106,889,850 (GRCm39) |
W374* |
probably null |
Het |
| Ptpn14 |
G |
A |
1: 189,554,839 (GRCm39) |
C133Y |
probably damaging |
Het |
| Ptpn20 |
A |
G |
14: 33,336,446 (GRCm39) |
N95S |
probably benign |
Het |
| Ptrh2 |
G |
T |
11: 86,580,862 (GRCm39) |
V160F |
probably damaging |
Het |
| Rapgef3 |
T |
C |
15: 97,655,256 (GRCm39) |
D486G |
probably damaging |
Het |
| Rev3l |
T |
G |
10: 39,699,981 (GRCm39) |
S1493A |
probably benign |
Het |
| Rgs9 |
T |
A |
11: 109,116,570 (GRCm39) |
D411V |
probably benign |
Het |
| Rgsl1 |
A |
T |
1: 153,669,514 (GRCm39) |
Y291N |
probably damaging |
Het |
| Rprd2 |
A |
G |
3: 95,671,849 (GRCm39) |
Y1185H |
probably damaging |
Het |
| Rpusd3 |
A |
G |
6: 113,393,167 (GRCm39) |
|
probably benign |
Het |
| Scnn1a |
T |
C |
6: 125,299,136 (GRCm39) |
I72T |
probably damaging |
Het |
| Sdk1 |
A |
T |
5: 141,842,758 (GRCm39) |
|
probably benign |
Het |
| Sfmbt2 |
T |
C |
2: 10,450,556 (GRCm39) |
L277P |
probably benign |
Het |
| Sgf29 |
A |
G |
7: 126,264,154 (GRCm39) |
E73G |
probably damaging |
Het |
| Slc12a6 |
T |
A |
2: 112,183,306 (GRCm39) |
F764L |
probably damaging |
Het |
| Slc4a2 |
T |
C |
5: 24,640,340 (GRCm39) |
|
probably null |
Het |
| Slc9a3 |
T |
G |
13: 74,305,838 (GRCm39) |
V285G |
probably damaging |
Het |
| Slc9c1 |
A |
G |
16: 45,395,772 (GRCm39) |
T608A |
probably benign |
Het |
| Slfnl1 |
C |
T |
4: 120,392,882 (GRCm39) |
R325C |
probably damaging |
Het |
| Smarcad1 |
T |
A |
6: 65,051,898 (GRCm39) |
F344I |
probably benign |
Het |
| Snrnp70 |
A |
T |
7: 45,026,705 (GRCm39) |
|
probably null |
Het |
| Sod2 |
C |
T |
17: 13,227,073 (GRCm39) |
T9M |
probably benign |
Het |
| Spag5 |
T |
A |
11: 78,205,199 (GRCm39) |
S633T |
probably damaging |
Het |
| Spta1 |
A |
T |
1: 174,018,622 (GRCm39) |
I531L |
probably benign |
Het |
| Stra8 |
A |
G |
6: 34,910,091 (GRCm39) |
E60G |
probably benign |
Het |
| Sult2a3 |
T |
A |
7: 13,845,482 (GRCm39) |
I126F |
probably benign |
Het |
| Syt1 |
T |
C |
10: 108,340,373 (GRCm39) |
H315R |
possibly damaging |
Het |
| Tanc2 |
T |
C |
11: 105,758,588 (GRCm39) |
L783P |
probably damaging |
Het |
| Thbs2 |
C |
T |
17: 14,899,162 (GRCm39) |
C646Y |
probably damaging |
Het |
| Ticam2 |
T |
A |
18: 46,693,989 (GRCm39) |
K33* |
probably null |
Het |
| Trim17 |
T |
C |
11: 58,845,127 (GRCm39) |
|
probably benign |
Het |
| Tsr1 |
G |
A |
11: 74,798,705 (GRCm39) |
M691I |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,592,763 (GRCm39) |
I20790F |
probably damaging |
Het |
| Tubb2b |
A |
T |
13: 34,312,168 (GRCm39) |
Y208* |
probably null |
Het |
| Ubr1 |
T |
A |
2: 120,745,419 (GRCm39) |
I890F |
probably damaging |
Het |
| Usp54 |
T |
C |
14: 20,612,260 (GRCm39) |
E852G |
probably damaging |
Het |
| Vmn2r78 |
T |
C |
7: 86,603,835 (GRCm39) |
V671A |
probably damaging |
Het |
| Wipi1 |
T |
C |
11: 109,470,475 (GRCm39) |
K315E |
probably benign |
Het |
| Xrn2 |
T |
C |
2: 146,893,638 (GRCm39) |
V735A |
possibly damaging |
Het |
| Zdbf2 |
T |
A |
1: 63,347,973 (GRCm39) |
D2117E |
possibly damaging |
Het |
| Zfp287 |
A |
T |
11: 62,604,962 (GRCm39) |
C648* |
probably null |
Het |
| Zfp369 |
A |
G |
13: 65,444,614 (GRCm39) |
T586A |
possibly damaging |
Het |
|
| Other mutations in Abca14 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00486:Abca14
|
APN |
7 |
119,846,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00800:Abca14
|
APN |
7 |
119,854,613 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00845:Abca14
|
APN |
7 |
119,823,174 (GRCm39) |
splice site |
probably benign |
|
|
IGL00897:Abca14
|
APN |
7 |
119,815,348 (GRCm39) |
splice site |
probably benign |
|
|
IGL01524:Abca14
|
APN |
7 |
119,852,644 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL01747:Abca14
|
APN |
7 |
119,877,310 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02214:Abca14
|
APN |
7 |
119,893,398 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02215:Abca14
|
APN |
7 |
119,852,612 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02253:Abca14
|
APN |
7 |
119,807,182 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02302:Abca14
|
APN |
7 |
119,917,968 (GRCm39) |
splice site |
probably benign |
|
|
IGL03391:Abca14
|
APN |
7 |
119,846,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F6893:Abca14
|
UTSW |
7 |
119,924,261 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0109:Abca14
|
UTSW |
7 |
119,917,985 (GRCm39) |
nonsense |
probably null |
|
|
R0109:Abca14
|
UTSW |
7 |
119,917,985 (GRCm39) |
nonsense |
probably null |
|
|
R0265:Abca14
|
UTSW |
7 |
119,822,850 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0326:Abca14
|
UTSW |
7 |
119,823,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Abca14
|
UTSW |
7 |
119,877,703 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0418:Abca14
|
UTSW |
7 |
119,806,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0539:Abca14
|
UTSW |
7 |
119,807,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0574:Abca14
|
UTSW |
7 |
119,823,720 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0611:Abca14
|
UTSW |
7 |
119,851,479 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R0783:Abca14
|
UTSW |
7 |
119,893,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0785:Abca14
|
UTSW |
7 |
119,893,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0863:Abca14
|
UTSW |
7 |
119,815,453 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1034:Abca14
|
UTSW |
7 |
119,815,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1056:Abca14
|
UTSW |
7 |
119,924,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1072:Abca14
|
UTSW |
7 |
119,811,992 (GRCm39) |
missense |
probably benign |
|
|
R1244:Abca14
|
UTSW |
7 |
119,815,561 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1255:Abca14
|
UTSW |
7 |
119,807,016 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1271:Abca14
|
UTSW |
7 |
119,924,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1325:Abca14
|
UTSW |
7 |
119,846,545 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1457:Abca14
|
UTSW |
7 |
119,888,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1467:Abca14
|
UTSW |
7 |
119,815,405 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1467:Abca14
|
UTSW |
7 |
119,815,405 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1494:Abca14
|
UTSW |
7 |
119,815,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1551:Abca14
|
UTSW |
7 |
119,918,101 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1607:Abca14
|
UTSW |
7 |
119,850,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1739:Abca14
|
UTSW |
7 |
119,877,529 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1856:Abca14
|
UTSW |
7 |
119,877,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Abca14
|
UTSW |
7 |
119,847,190 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1892:Abca14
|
UTSW |
7 |
119,815,561 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1898:Abca14
|
UTSW |
7 |
119,850,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1958:Abca14
|
UTSW |
7 |
119,924,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2018:Abca14
|
UTSW |
7 |
119,815,408 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2039:Abca14
|
UTSW |
7 |
119,911,487 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2060:Abca14
|
UTSW |
7 |
119,826,741 (GRCm39) |
nonsense |
probably null |
|
|
R2202:Abca14
|
UTSW |
7 |
119,888,764 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2205:Abca14
|
UTSW |
7 |
119,846,503 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2360:Abca14
|
UTSW |
7 |
119,850,431 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2401:Abca14
|
UTSW |
7 |
119,882,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2426:Abca14
|
UTSW |
7 |
119,882,446 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3433:Abca14
|
UTSW |
7 |
119,893,455 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4598:Abca14
|
UTSW |
7 |
119,854,626 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4599:Abca14
|
UTSW |
7 |
119,854,626 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4700:Abca14
|
UTSW |
7 |
119,911,928 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4751:Abca14
|
UTSW |
7 |
119,911,400 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4826:Abca14
|
UTSW |
7 |
119,815,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4828:Abca14
|
UTSW |
7 |
119,815,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4837:Abca14
|
UTSW |
7 |
119,846,203 (GRCm39) |
missense |
probably benign |
|
|
R4881:Abca14
|
UTSW |
7 |
119,877,472 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4895:Abca14
|
UTSW |
7 |
119,846,572 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4990:Abca14
|
UTSW |
7 |
119,911,388 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Abca14
|
UTSW |
7 |
119,911,505 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5091:Abca14
|
UTSW |
7 |
119,851,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5158:Abca14
|
UTSW |
7 |
119,852,652 (GRCm39) |
missense |
probably benign |
|
|
R5209:Abca14
|
UTSW |
7 |
119,832,130 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5333:Abca14
|
UTSW |
7 |
119,888,769 (GRCm39) |
nonsense |
probably null |
|
|
R5424:Abca14
|
UTSW |
7 |
119,810,777 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5488:Abca14
|
UTSW |
7 |
119,851,473 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5489:Abca14
|
UTSW |
7 |
119,851,473 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5716:Abca14
|
UTSW |
7 |
119,846,217 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6450:Abca14
|
UTSW |
7 |
119,815,449 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6477:Abca14
|
UTSW |
7 |
119,924,325 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6652:Abca14
|
UTSW |
7 |
119,846,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6782:Abca14
|
UTSW |
7 |
119,847,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6874:Abca14
|
UTSW |
7 |
119,851,428 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6965:Abca14
|
UTSW |
7 |
119,882,452 (GRCm39) |
nonsense |
probably null |
|
|
R7142:Abca14
|
UTSW |
7 |
119,850,406 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7146:Abca14
|
UTSW |
7 |
119,854,520 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7202:Abca14
|
UTSW |
7 |
119,917,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7220:Abca14
|
UTSW |
7 |
119,826,667 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R7241:Abca14
|
UTSW |
7 |
119,846,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7291:Abca14
|
UTSW |
7 |
119,888,832 (GRCm39) |
nonsense |
probably null |
|
|
R7296:Abca14
|
UTSW |
7 |
119,877,534 (GRCm39) |
missense |
probably benign |
|
|
R7298:Abca14
|
UTSW |
7 |
119,807,106 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7315:Abca14
|
UTSW |
7 |
119,893,341 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7776:Abca14
|
UTSW |
7 |
119,832,214 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7820:Abca14
|
UTSW |
7 |
119,811,944 (GRCm39) |
missense |
probably benign |
0.42 |
|
R7873:Abca14
|
UTSW |
7 |
119,888,792 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8215:Abca14
|
UTSW |
7 |
119,893,425 (GRCm39) |
missense |
probably benign |
|
|
R8332:Abca14
|
UTSW |
7 |
119,815,436 (GRCm39) |
missense |
probably benign |
|
|
R8419:Abca14
|
UTSW |
7 |
119,815,489 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8444:Abca14
|
UTSW |
7 |
119,918,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8818:Abca14
|
UTSW |
7 |
119,815,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8834:Abca14
|
UTSW |
7 |
119,877,372 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8845:Abca14
|
UTSW |
7 |
119,846,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8889:Abca14
|
UTSW |
7 |
119,815,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8892:Abca14
|
UTSW |
7 |
119,815,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8894:Abca14
|
UTSW |
7 |
119,847,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8903:Abca14
|
UTSW |
7 |
119,815,526 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8950:Abca14
|
UTSW |
7 |
119,823,595 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8950:Abca14
|
UTSW |
7 |
119,823,644 (GRCm39) |
nonsense |
probably null |
|
|
R9018:Abca14
|
UTSW |
7 |
119,918,532 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9018:Abca14
|
UTSW |
7 |
119,888,763 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9110:Abca14
|
UTSW |
7 |
119,831,615 (GRCm39) |
intron |
probably benign |
|
|
R9254:Abca14
|
UTSW |
7 |
119,807,202 (GRCm39) |
nonsense |
probably null |
|
|
R9376:Abca14
|
UTSW |
7 |
119,893,438 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9378:Abca14
|
UTSW |
7 |
119,807,191 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9379:Abca14
|
UTSW |
7 |
119,807,202 (GRCm39) |
nonsense |
probably null |
|
|
R9388:Abca14
|
UTSW |
7 |
119,882,261 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9445:Abca14
|
UTSW |
7 |
119,877,691 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9522:Abca14
|
UTSW |
7 |
119,847,368 (GRCm39) |
missense |
probably null |
0.98 |
|
R9577:Abca14
|
UTSW |
7 |
119,810,768 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9627:Abca14
|
UTSW |
7 |
119,854,530 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9639:Abca14
|
UTSW |
7 |
119,893,345 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Abca14
|
UTSW |
7 |
119,851,478 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9696:Abca14
|
UTSW |
7 |
119,888,734 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9709:Abca14
|
UTSW |
7 |
119,888,739 (GRCm39) |
nonsense |
probably null |
|
|
R9780:Abca14
|
UTSW |
7 |
119,911,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Abca14
|
UTSW |
7 |
119,815,358 (GRCm39) |
missense |
probably benign |
0.14 |
|
Z1176:Abca14
|
UTSW |
7 |
119,846,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Abca14
|
UTSW |
7 |
119,917,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGGGCAACTGTCATGTACTCC -3'
(R):5'- CTGAAAGTTAACATGAGTGCTAGCAC -3'
Sequencing Primer
(F):5'- TAGAAGGTCCCCATAAGGCTCATG -3'
(R):5'- GTGCTAGCACATCCGCAATG -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation