Incidental Mutation 'R0400:Prdm2'
| ID |
38118 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prdm2
|
| Ensembl Gene |
ENSMUSG00000057637 |
| Gene Name |
PR domain containing 2, with ZNF domain |
| Synonyms |
KMT8, LOC381568, E330024L24Rik, Riz1, Riz, 4833427P12Rik |
| MMRRC Submission |
038605-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0400 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
143107391-143212995 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 143111670 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Serine
at position 1706
(F1706S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101404
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000105778]
|
| AlphaFold |
A2A7B5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000105778
AA Change: F1706S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000101404
Gene: ENSMUSG00000057637
AA Change: F1706S
| Domain | Start | End | E-Value | Type |
|---|
|
SET
|
29 |
146 |
2.79e-21 |
SMART |
|
coiled coil region
|
254 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
333 |
346 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
356 |
378 |
2.95e-3 |
SMART |
|
ZnF_C2H2
|
386 |
408 |
4.79e-3 |
SMART |
|
ZnF_C2H2
|
477 |
500 |
4.17e-3 |
SMART |
|
low complexity region
|
517 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
697 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
744 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
931 |
951 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
992 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1035 |
1080 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1126 |
1148 |
3.52e-1 |
SMART |
|
ZnF_C2H2
|
1154 |
1177 |
7.55e-1 |
SMART |
|
ZnF_C2H2
|
1183 |
1206 |
4.72e-2 |
SMART |
|
low complexity region
|
1239 |
1253 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1324 |
1344 |
5.12e1 |
SMART |
|
low complexity region
|
1406 |
1423 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1446 |
1466 |
1.86e1 |
SMART |
|
low complexity region
|
1475 |
1507 |
N/A |
INTRINSIC |
|
low complexity region
|
1551 |
1568 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0628 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.8%
|
| Validation Efficiency |
97% (76/78) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
PHENOTYPE: Homozygous null mice have shortened life spans, becoming moribund due to increased incidence of tumors. Mice had a broad spectrum of unusual tumors in multiple organs, with a high incidence of diffuse large B cell lymphomas. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930505A04Rik |
T |
A |
11: 30,426,360 (GRCm38) |
H169L |
probably benign |
Het |
| 9130230L23Rik |
T |
C |
5: 65,990,356 (GRCm38) |
D28G |
unknown |
Het |
| Abca12 |
T |
A |
1: 71,259,776 (GRCm38) |
|
probably benign |
Het |
| Acsl5 |
T |
C |
19: 55,293,711 (GRCm38) |
V573A |
probably damaging |
Het |
| Agap1 |
A |
G |
1: 89,843,250 (GRCm38) |
|
probably benign |
Het |
| Arid2 |
A |
G |
15: 96,356,925 (GRCm38) |
|
probably benign |
Het |
| B430305J03Rik |
T |
A |
3: 61,364,135 (GRCm38) |
|
probably benign |
Het |
| Brsk2 |
T |
C |
7: 141,998,553 (GRCm38) |
L584P |
probably damaging |
Het |
| C2cd4c |
A |
G |
10: 79,613,209 (GRCm38) |
Y35H |
probably damaging |
Het |
| Cacul1 |
A |
G |
19: 60,563,153 (GRCm38) |
|
probably benign |
Het |
| Cers3 |
T |
C |
7: 66,764,330 (GRCm38) |
V88A |
probably benign |
Het |
| Cnnm1 |
A |
T |
19: 43,468,364 (GRCm38) |
H614L |
probably damaging |
Het |
| Col1a1 |
T |
A |
11: 94,941,369 (GRCm38) |
|
probably benign |
Het |
| Cyp1b1 |
T |
A |
17: 79,713,587 (GRCm38) |
D242V |
probably damaging |
Het |
| Cyp4a31 |
T |
C |
4: 115,563,718 (GRCm38) |
M1T |
probably null |
Het |
| Dbn1 |
C |
T |
13: 55,474,916 (GRCm38) |
E585K |
probably damaging |
Het |
| Dclk2 |
A |
T |
3: 86,813,747 (GRCm38) |
|
probably null |
Het |
| Dnah17 |
A |
G |
11: 118,082,078 (GRCm38) |
S2010P |
probably damaging |
Het |
| Dram2 |
T |
C |
3: 106,573,618 (GRCm38) |
L246P |
probably damaging |
Het |
| Dus2 |
A |
T |
8: 106,048,677 (GRCm38) |
T279S |
probably benign |
Het |
| Epn2 |
T |
C |
11: 61,532,696 (GRCm38) |
|
probably null |
Het |
| Esco2 |
C |
A |
14: 65,831,706 (GRCm38) |
V52F |
possibly damaging |
Het |
| Fbp1 |
T |
A |
13: 62,865,068 (GRCm38) |
T104S |
probably benign |
Het |
| Foxj2 |
A |
T |
6: 122,833,808 (GRCm38) |
Q249L |
possibly damaging |
Het |
| Galnt7 |
T |
C |
8: 57,583,989 (GRCm38) |
Y122C |
probably damaging |
Het |
| Gimd1 |
T |
C |
3: 132,634,827 (GRCm38) |
Y35H |
probably benign |
Het |
| Gipc2 |
A |
G |
3: 152,165,668 (GRCm38) |
F74L |
probably damaging |
Het |
| Glt1d1 |
T |
A |
5: 127,657,075 (GRCm38) |
|
probably benign |
Het |
| Hmcn2 |
A |
G |
2: 31,400,129 (GRCm38) |
T2325A |
probably damaging |
Het |
| Iffo1 |
A |
G |
6: 125,153,471 (GRCm38) |
K471R |
probably damaging |
Het |
| Ireb2 |
G |
A |
9: 54,896,498 (GRCm38) |
R491H |
probably benign |
Het |
| Isg20 |
A |
G |
7: 78,916,725 (GRCm38) |
N141D |
possibly damaging |
Het |
| Kmt5c |
G |
A |
7: 4,746,244 (GRCm38) |
R100H |
probably benign |
Het |
| Lrp1b |
T |
C |
2: 40,750,914 (GRCm38) |
D3506G |
probably benign |
Het |
| Lrrn4 |
A |
C |
2: 132,878,020 (GRCm38) |
F287V |
probably benign |
Het |
| Maco1 |
T |
C |
4: 134,828,116 (GRCm38) |
K349E |
probably benign |
Het |
| Mmrn1 |
A |
C |
6: 60,977,115 (GRCm38) |
K793N |
probably benign |
Het |
| Muc16 |
A |
G |
9: 18,510,534 (GRCm38) |
V8227A |
possibly damaging |
Het |
| Myh2 |
C |
T |
11: 67,192,598 (GRCm38) |
|
probably benign |
Het |
| Nalcn |
T |
A |
14: 123,290,960 (GRCm38) |
|
probably benign |
Het |
| Nfia |
T |
C |
4: 98,063,136 (GRCm38) |
V400A |
probably damaging |
Het |
| Nxph4 |
T |
A |
10: 127,526,258 (GRCm38) |
T255S |
possibly damaging |
Het |
| Olfm5 |
G |
A |
7: 104,154,179 (GRCm38) |
T359I |
probably damaging |
Het |
| Or1e33 |
T |
C |
11: 73,848,041 (GRCm38) |
Y28C |
probably benign |
Het |
| Or5t18 |
A |
G |
2: 86,806,651 (GRCm38) |
M116T |
probably damaging |
Het |
| Or8b44 |
A |
G |
9: 38,498,911 (GRCm38) |
M81V |
possibly damaging |
Het |
| Or8g21 |
G |
T |
9: 38,995,198 (GRCm38) |
P79Q |
probably damaging |
Het |
| Pak5 |
T |
C |
2: 136,097,579 (GRCm38) |
I545M |
possibly damaging |
Het |
| Pcdhb15 |
T |
C |
18: 37,475,895 (GRCm38) |
F727L |
probably benign |
Het |
| Pds5b |
T |
A |
5: 150,723,353 (GRCm38) |
N202K |
possibly damaging |
Het |
| Phlpp1 |
T |
A |
1: 106,392,934 (GRCm38) |
I1553N |
probably benign |
Het |
| Pink1 |
T |
C |
4: 138,317,918 (GRCm38) |
T282A |
probably damaging |
Het |
| Pycr1 |
G |
A |
11: 120,641,526 (GRCm38) |
|
probably benign |
Het |
| Rigi |
A |
G |
4: 40,235,257 (GRCm38) |
Y78H |
probably benign |
Het |
| Skint9 |
A |
G |
4: 112,414,001 (GRCm38) |
S71P |
probably damaging |
Het |
| Smad1 |
A |
G |
8: 79,371,770 (GRCm38) |
|
probably benign |
Het |
| Snapc5 |
A |
T |
9: 64,180,507 (GRCm38) |
E33D |
probably damaging |
Het |
| Snrnp40 |
T |
C |
4: 130,362,650 (GRCm38) |
L56P |
probably damaging |
Het |
| Stab2 |
A |
C |
10: 86,872,610 (GRCm38) |
I1697S |
probably damaging |
Het |
| Tfap2a |
G |
T |
13: 40,717,412 (GRCm38) |
|
probably benign |
Het |
| Tph2 |
A |
G |
10: 115,080,120 (GRCm38) |
|
probably benign |
Het |
| Triml1 |
A |
G |
8: 43,141,040 (GRCm38) |
V118A |
probably benign |
Het |
| Ttbk2 |
T |
A |
2: 120,750,242 (GRCm38) |
T538S |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,715,272 (GRCm38) |
V32569A |
possibly damaging |
Het |
| U2af1 |
T |
A |
17: 31,648,192 (GRCm38) |
Y158F |
probably benign |
Het |
| Usp7 |
A |
T |
16: 8,716,632 (GRCm38) |
|
probably benign |
Het |
| Vdr |
A |
G |
15: 97,869,351 (GRCm38) |
S179P |
probably benign |
Het |
| Vps13d |
A |
C |
4: 145,065,827 (GRCm38) |
S663A |
probably benign |
Het |
| Wdr62 |
T |
A |
7: 30,241,462 (GRCm38) |
T844S |
possibly damaging |
Het |
| Wipi1 |
C |
T |
11: 109,577,130 (GRCm38) |
R407Q |
probably damaging |
Het |
| Zbtb43 |
A |
G |
2: 33,453,897 (GRCm38) |
C439R |
probably damaging |
Het |
| Zfp507 |
T |
A |
7: 35,791,746 (GRCm38) |
H704L |
probably damaging |
Het |
| Zzef1 |
G |
A |
11: 72,895,242 (GRCm38) |
R2080K |
probably damaging |
Het |
|
| Other mutations in Prdm2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00530:Prdm2
|
APN |
4 |
143,133,759 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL00843:Prdm2
|
APN |
4 |
143,134,314 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01419:Prdm2
|
APN |
4 |
143,133,648 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01662:Prdm2
|
APN |
4 |
143,133,568 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
IGL01892:Prdm2
|
APN |
4 |
143,134,404 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02104:Prdm2
|
APN |
4 |
143,133,427 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02208:Prdm2
|
APN |
4 |
143,135,743 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02260:Prdm2
|
APN |
4 |
143,134,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02479:Prdm2
|
APN |
4 |
143,134,929 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02943:Prdm2
|
APN |
4 |
143,131,972 (GRCm38) |
missense |
probably benign |
|
|
IGL02972:Prdm2
|
APN |
4 |
143,132,166 (GRCm38) |
missense |
probably benign |
|
|
IGL03038:Prdm2
|
APN |
4 |
143,134,001 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03399:Prdm2
|
APN |
4 |
143,135,088 (GRCm38) |
missense |
probably benign |
0.07 |
|
G1patch:Prdm2
|
UTSW |
4 |
143,132,901 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
PIT4677001:Prdm2
|
UTSW |
4 |
143,135,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0088:Prdm2
|
UTSW |
4 |
143,134,954 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R0153:Prdm2
|
UTSW |
4 |
143,133,768 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0320:Prdm2
|
UTSW |
4 |
143,179,351 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0384:Prdm2
|
UTSW |
4 |
143,135,688 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0658:Prdm2
|
UTSW |
4 |
143,135,265 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0850:Prdm2
|
UTSW |
4 |
143,132,203 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1118:Prdm2
|
UTSW |
4 |
143,132,383 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R1355:Prdm2
|
UTSW |
4 |
143,131,963 (GRCm38) |
missense |
probably benign |
0.33 |
|
R1519:Prdm2
|
UTSW |
4 |
143,135,583 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1936:Prdm2
|
UTSW |
4 |
143,134,462 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1987:Prdm2
|
UTSW |
4 |
143,132,509 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R2006:Prdm2
|
UTSW |
4 |
143,131,877 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R2008:Prdm2
|
UTSW |
4 |
143,134,947 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2030:Prdm2
|
UTSW |
4 |
143,132,764 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R2112:Prdm2
|
UTSW |
4 |
143,131,936 (GRCm38) |
missense |
probably benign |
|
|
R2221:Prdm2
|
UTSW |
4 |
143,134,899 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R2223:Prdm2
|
UTSW |
4 |
143,134,899 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R2426:Prdm2
|
UTSW |
4 |
143,111,750 (GRCm38) |
nonsense |
probably null |
|
|
R2430:Prdm2
|
UTSW |
4 |
143,133,163 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R2484:Prdm2
|
UTSW |
4 |
143,135,206 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3735:Prdm2
|
UTSW |
4 |
143,134,359 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3944:Prdm2
|
UTSW |
4 |
143,131,815 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R4209:Prdm2
|
UTSW |
4 |
143,134,437 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4411:Prdm2
|
UTSW |
4 |
143,133,670 (GRCm38) |
missense |
probably benign |
0.18 |
|
R4647:Prdm2
|
UTSW |
4 |
143,132,955 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R4898:Prdm2
|
UTSW |
4 |
143,134,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5032:Prdm2
|
UTSW |
4 |
143,179,367 (GRCm38) |
nonsense |
probably null |
|
|
R5181:Prdm2
|
UTSW |
4 |
143,134,966 (GRCm38) |
missense |
probably benign |
0.35 |
|
R5513:Prdm2
|
UTSW |
4 |
143,135,893 (GRCm38) |
small deletion |
probably benign |
|
|
R5539:Prdm2
|
UTSW |
4 |
143,132,694 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R5563:Prdm2
|
UTSW |
4 |
143,134,630 (GRCm38) |
missense |
probably benign |
0.09 |
|
R5618:Prdm2
|
UTSW |
4 |
143,133,537 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5900:Prdm2
|
UTSW |
4 |
143,134,720 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5990:Prdm2
|
UTSW |
4 |
143,170,113 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6148:Prdm2
|
UTSW |
4 |
143,132,907 (GRCm38) |
missense |
probably benign |
0.33 |
|
R6166:Prdm2
|
UTSW |
4 |
143,134,736 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6223:Prdm2
|
UTSW |
4 |
143,142,207 (GRCm38) |
missense |
probably benign |
0.41 |
|
R6530:Prdm2
|
UTSW |
4 |
143,134,047 (GRCm38) |
missense |
probably benign |
0.05 |
|
R6631:Prdm2
|
UTSW |
4 |
143,134,884 (GRCm38) |
missense |
probably benign |
0.05 |
|
R6725:Prdm2
|
UTSW |
4 |
143,132,901 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R6847:Prdm2
|
UTSW |
4 |
143,132,950 (GRCm38) |
missense |
probably benign |
0.18 |
|
R7193:Prdm2
|
UTSW |
4 |
143,180,894 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7238:Prdm2
|
UTSW |
4 |
143,135,821 (GRCm38) |
missense |
probably benign |
0.35 |
|
R7292:Prdm2
|
UTSW |
4 |
143,132,901 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R7417:Prdm2
|
UTSW |
4 |
143,179,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7748:Prdm2
|
UTSW |
4 |
143,135,889 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7885:Prdm2
|
UTSW |
4 |
143,134,570 (GRCm38) |
missense |
probably benign |
0.41 |
|
R7936:Prdm2
|
UTSW |
4 |
143,135,864 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7976:Prdm2
|
UTSW |
4 |
143,133,242 (GRCm38) |
nonsense |
probably null |
|
|
R8124:Prdm2
|
UTSW |
4 |
143,135,265 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8150:Prdm2
|
UTSW |
4 |
143,132,733 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R8156:Prdm2
|
UTSW |
4 |
143,134,768 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8178:Prdm2
|
UTSW |
4 |
143,132,448 (GRCm38) |
missense |
probably benign |
0.33 |
|
R8235:Prdm2
|
UTSW |
4 |
143,132,467 (GRCm38) |
nonsense |
probably null |
|
|
R8404:Prdm2
|
UTSW |
4 |
143,135,014 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8498:Prdm2
|
UTSW |
4 |
143,180,897 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8502:Prdm2
|
UTSW |
4 |
143,135,014 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8688:Prdm2
|
UTSW |
4 |
143,111,740 (GRCm38) |
missense |
probably benign |
|
|
R8732:Prdm2
|
UTSW |
4 |
143,136,010 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8796:Prdm2
|
UTSW |
4 |
143,133,447 (GRCm38) |
missense |
probably benign |
0.33 |
|
R8874:Prdm2
|
UTSW |
4 |
143,133,215 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R8887:Prdm2
|
UTSW |
4 |
143,134,201 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9119:Prdm2
|
UTSW |
4 |
143,131,879 (GRCm38) |
nonsense |
probably null |
|
|
R9139:Prdm2
|
UTSW |
4 |
143,132,182 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9165:Prdm2
|
UTSW |
4 |
143,132,104 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R9342:Prdm2
|
UTSW |
4 |
143,134,908 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9518:Prdm2
|
UTSW |
4 |
143,134,009 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9546:Prdm2
|
UTSW |
4 |
143,134,991 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9547:Prdm2
|
UTSW |
4 |
143,134,991 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9680:Prdm2
|
UTSW |
4 |
143,132,509 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R9730:Prdm2
|
UTSW |
4 |
143,132,089 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
X0017:Prdm2
|
UTSW |
4 |
143,134,707 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ATGCACTGATCTCATCGCTGGAC -3'
(R):5'- ACTGGTTGCTGCTGATGACCTG -3'
Sequencing Primer
(F):5'- aatgggcaacatcaacacag -3'
(R):5'- TGCTGATGACCTGCGCTC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation