Mutagenetix > Incidental Mutation

Incidental Mutation 'R4954:Dnah2'

381492

Institutional Source

Beutler Lab

Gene Symbol

Dnah2

Ensembl Gene

ENSMUSG00000005237

Gene Name

dynein, axonemal, heavy chain 2

Synonyms

2900022L05Rik, D330014H01Rik, Dnahc2, Dnhd3

MMRRC Submission

042551-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4954 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

69311635-69439934 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 69430322 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Proline to Serine at position 79 (P79S)

Ref Sequence

ENSEMBL: ENSMUSP00000104299 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000035539] [ENSMUST00000108659]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000035539
AA Change: P79S

PolyPhen 2 Score 0.613 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000047329
Gene: ENSMUSG00000005237
AA Change: P79S

Domain	Start	End	E-Value	Type
low complexity region	4	25	N/A	INTRINSIC
Pfam:DHC_N1	273	429	6.6e-37	PFAM
Pfam:DHC_N1	432	761	1.3e-54	PFAM
Pfam:DHC_N2	1253	1668	3.4e-144	PFAM
AAA	1826	1962	2.95e-1	SMART
Pfam:AAA_5	2108	2251	1.3e-5	PFAM
AAA	2437	2584	3.63e-5	SMART
Pfam:AAA_8	2752	3022	1.1e-75	PFAM
Pfam:MT	3034	3370	8.7e-55	PFAM
Pfam:AAA_9	3386	3616	7.4e-68	PFAM
Pfam:Dynein_heavy	3748	4453	1.2e-220	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000108659
AA Change: P79S

PolyPhen 2 Score 0.613 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000104299
Gene: ENSMUSG00000005237
AA Change: P79S

Domain	Start	End	E-Value	Type
low complexity region	4	25	N/A	INTRINSIC
Pfam:DHC_N1	274	429	1.1e-47	PFAM
Pfam:DHC_N1	438	760	1.5e-75	PFAM
Pfam:DHC_N2	1255	1666	4.4e-144	PFAM
low complexity region	1711	1720	N/A	INTRINSIC
AAA	1832	1968	2.95e-1	SMART
Blast:AAA	2111	2251	2e-86	BLAST
AAA	2443	2590	3.63e-5	SMART
Pfam:AAA_8	2758	3028	5.5e-77	PFAM
Pfam:MT	3040	3376	7.6e-55	PFAM
Pfam:AAA_9	3396	3621	7.5e-94	PFAM
Pfam:Dynein_heavy	3759	4458	4.9e-264	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000149991

Meta Mutation Damage Score

0.1795

Coding Region Coverage

1x: 99.2%
3x: 98.4%
10x: 96.7%
20x: 93.7%

Validation Efficiency

100% (66/66)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]

Allele List at MGI

Other mutations in this stock

Total: 55 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb5	G	A	12: 118,875,169 (GRCm39)	H668Y	probably benign	Het
Alk	C	T	17: 72,209,687 (GRCm39)	W919*	probably null	Het
Aoc3	G	A	11: 101,222,925 (GRCm39)	G387D	probably damaging	Het
Arhgap26	T	A	18: 39,376,694 (GRCm39)	C441S	probably benign	Het
Arhgap28	C	A	17: 68,176,008 (GRCm39)	E100*	probably null	Het
Ate1	C	T	7: 130,110,748 (GRCm39)	G186D	probably benign	Het
Birc6	T	A	17: 74,919,026 (GRCm39)	L1948H	probably damaging	Het
Bmp2k	C	T	5: 97,234,623 (GRCm39)		probably benign	Het
Ccin	A	T	4: 43,985,077 (GRCm39)	I495F	probably benign	Het
Cir1	T	A	2: 73,140,848 (GRCm39)	E40D	probably benign	Het
Cyp3a57	A	T	5: 145,307,765 (GRCm39)		probably null	Het
Dennd1b	A	G	1: 138,981,124 (GRCm39)	T113A	probably damaging	Het
Dync1h1	C	A	12: 110,624,560 (GRCm39)	T3700N	probably damaging	Het
Dync2i1	T	C	12: 116,219,645 (GRCm39)	D99G	probably damaging	Het
Enpep	A	T	3: 129,077,829 (GRCm39)	I596N	probably damaging	Het
Eps15	G	A	4: 109,227,875 (GRCm39)		probably null	Het
Ext1	T	C	15: 53,207,888 (GRCm39)	D291G	probably damaging	Het
Gm12883	T	C	4: 121,252,198 (GRCm39)		noncoding transcript	Het
Gm9921	A	G	12: 45,484,383 (GRCm39)		noncoding transcript	Het
H2-T22	C	A	17: 36,352,851 (GRCm39)	W85C	probably damaging	Het
Heatr1	G	A	13: 12,422,397 (GRCm39)		probably null	Het
Hspa4l	T	A	3: 40,739,832 (GRCm39)		probably null	Het
Kcnc3	CTT	CT	7: 44,240,720 (GRCm39)		probably null	Het
Kpna1	T	C	16: 35,853,696 (GRCm39)	V442A	probably damaging	Het
Mogat2	T	C	7: 98,887,724 (GRCm39)	T17A	possibly damaging	Het
Musk	C	T	4: 58,344,222 (GRCm39)	T285I	probably damaging	Het
Myorg	G	A	4: 41,498,241 (GRCm39)	A463V	possibly damaging	Het
Nbea	T	G	3: 55,943,379 (GRCm39)	Q632P	probably damaging	Het
Ncoa3	T	C	2: 165,907,706 (GRCm39)	V1105A	probably benign	Het
Neb	T	C	2: 52,067,530 (GRCm39)		probably null	Het
Nlrp4e	A	T	7: 23,061,318 (GRCm39)	K970*	probably null	Het
Oog2	A	T	4: 143,917,302 (GRCm39)		probably benign	Het
Or13g1	T	C	7: 85,955,809 (GRCm39)	I171V	probably benign	Het
Or2a57	A	G	6: 43,213,318 (GRCm39)	M259V	probably benign	Het
Or52a24	A	G	7: 103,381,414 (GRCm39)	I94V	probably damaging	Het
Otos	T	C	1: 92,572,167 (GRCm39)	Y53C	probably damaging	Het
Oxct2a	A	T	4: 123,216,252 (GRCm39)	C376*	probably null	Het
Pate12	A	T	9: 36,344,156 (GRCm39)	K46N	probably benign	Het
Phf14	C	A	6: 11,987,619 (GRCm39)	Q633K	probably benign	Het
Pkdrej	T	A	15: 85,700,602 (GRCm39)	N1778I	probably damaging	Het
Psmc3	C	T	2: 90,885,974 (GRCm39)		probably benign	Het
Rbm33	A	T	5: 28,544,274 (GRCm39)	I177F	probably damaging	Het
Rps6ka2	A	G	17: 7,539,003 (GRCm39)	D307G	probably benign	Het
Rps6ka2	G	A	17: 7,566,685 (GRCm39)	V648I	probably benign	Het
Scn11a	C	T	9: 119,587,725 (GRCm39)	V1340M	possibly damaging	Het
Sema7a	T	C	9: 57,863,663 (GRCm39)	W279R	probably damaging	Het
Slc2a10	A	T	2: 165,356,675 (GRCm39)	I112F	probably damaging	Het
Stk4	C	A	2: 163,993,601 (GRCm39)	S77R	possibly damaging	Het
Stk4	T	A	2: 163,993,602 (GRCm39)	W78R	probably damaging	Het
Syf2	T	A	4: 134,662,283 (GRCm39)	L99*	probably null	Het
Tas2r104	A	T	6: 131,661,968 (GRCm39)	I247K	probably damaging	Het
Usp15	G	T	10: 122,967,303 (GRCm39)	R368S	probably damaging	Het
Usp5	C	G	6: 124,799,593 (GRCm39)	K318N	possibly damaging	Het
Vmn2r2	T	A	3: 64,047,905 (GRCm39)	L20F	probably benign	Het
Zcchc4	A	T	5: 52,976,559 (GRCm39)	H451L	probably damaging	Het

Other mutations in Dnah2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00087:Dnah2	APN	11	69,383,498 (GRCm39)	missense	possibly damaging	0.93
IGL00418:Dnah2	APN	11	69,385,892 (GRCm39)	splice site	probably benign
IGL00772:Dnah2	APN	11	69,342,083 (GRCm39)	missense	probably damaging	0.97
IGL00819:Dnah2	APN	11	69,364,176 (GRCm39)	critical splice donor site	probably null
IGL00827:Dnah2	APN	11	69,339,283 (GRCm39)	missense	probably damaging	1.00
IGL01060:Dnah2	APN	11	69,368,918 (GRCm39)	missense	possibly damaging	0.86
IGL01340:Dnah2	APN	11	69,384,010 (GRCm39)	missense	probably damaging	0.99
IGL01349:Dnah2	APN	11	69,366,432 (GRCm39)	missense	probably damaging	0.99
IGL01413:Dnah2	APN	11	69,323,790 (GRCm39)	missense	probably damaging	0.99
IGL01451:Dnah2	APN	11	69,365,017 (GRCm39)	splice site	probably benign
IGL01480:Dnah2	APN	11	69,349,197 (GRCm39)	missense	possibly damaging	0.91
IGL01537:Dnah2	APN	11	69,406,906 (GRCm39)	missense	probably benign	0.17
IGL01592:Dnah2	APN	11	69,321,913 (GRCm39)	missense	probably benign	0.14
IGL01612:Dnah2	APN	11	69,355,889 (GRCm39)	splice site	probably benign
IGL01667:Dnah2	APN	11	69,435,221 (GRCm39)	missense	probably benign
IGL01667:Dnah2	APN	11	69,411,767 (GRCm39)	missense	probably damaging	0.98
IGL01691:Dnah2	APN	11	69,430,269 (GRCm39)	missense	probably benign
IGL02019:Dnah2	APN	11	69,365,111 (GRCm39)	missense	probably damaging	1.00
IGL02039:Dnah2	APN	11	69,390,038 (GRCm39)	missense	probably damaging	1.00
IGL02076:Dnah2	APN	11	69,313,385 (GRCm39)	missense	probably damaging	0.99
IGL02085:Dnah2	APN	11	69,349,011 (GRCm39)	missense	probably benign	0.07
IGL02158:Dnah2	APN	11	69,348,949 (GRCm39)	missense	probably benign
IGL02381:Dnah2	APN	11	69,337,118 (GRCm39)	missense	probably benign	0.25
IGL02681:Dnah2	APN	11	69,343,759 (GRCm39)	missense	probably benign	0.40
IGL02957:Dnah2	APN	11	69,339,333 (GRCm39)	missense	possibly damaging	0.96
IGL02961:Dnah2	APN	11	69,409,240 (GRCm39)	missense	probably damaging	1.00
IGL02969:Dnah2	APN	11	69,412,013 (GRCm39)	missense	possibly damaging	0.80
IGL03117:Dnah2	APN	11	69,327,117 (GRCm39)	splice site	probably benign
IGL03120:Dnah2	APN	11	69,312,674 (GRCm39)	missense	probably damaging	1.00
IGL03183:Dnah2	APN	11	69,349,314 (GRCm39)	missense	possibly damaging	0.94
IGL03197:Dnah2	APN	11	69,350,089 (GRCm39)	missense	probably damaging	1.00
IGL03263:Dnah2	APN	11	69,420,207 (GRCm39)	critical splice donor site	probably null
IGL03333:Dnah2	APN	11	69,385,949 (GRCm39)	missense	probably damaging	1.00
IGL03338:Dnah2	APN	11	69,387,403 (GRCm39)	missense	probably benign	0.13
argyrios	UTSW	11	69,407,416 (GRCm39)	missense	possibly damaging	0.47
Aureus	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
platinum	UTSW	11	69,348,868 (GRCm39)	missense	probably damaging	0.96
R0334_dnah2_144	UTSW	11	69,327,662 (GRCm39)	missense	probably damaging	1.00
R2150_dnah2_212	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
BB005:Dnah2	UTSW	11	69,321,661 (GRCm39)	missense	probably damaging	0.98
BB015:Dnah2	UTSW	11	69,321,661 (GRCm39)	missense	probably damaging	0.98
E0370:Dnah2	UTSW	11	69,406,441 (GRCm39)	splice site	probably null
P0026:Dnah2	UTSW	11	69,355,773 (GRCm39)	missense	probably damaging	1.00
R0133:Dnah2	UTSW	11	69,311,835 (GRCm39)	missense	probably damaging	1.00
R0190:Dnah2	UTSW	11	69,326,075 (GRCm39)	missense	probably damaging	1.00
R0334:Dnah2	UTSW	11	69,327,662 (GRCm39)	missense	probably damaging	1.00
R0359:Dnah2	UTSW	11	69,420,357 (GRCm39)	missense	probably benign	0.00
R0386:Dnah2	UTSW	11	69,338,687 (GRCm39)	missense	probably damaging	1.00
R0414:Dnah2	UTSW	11	69,390,064 (GRCm39)	missense	probably benign	0.26
R0427:Dnah2	UTSW	11	69,343,705 (GRCm39)	missense	probably damaging	0.99
R0433:Dnah2	UTSW	11	69,350,114 (GRCm39)	missense	probably damaging	1.00
R0442:Dnah2	UTSW	11	69,339,368 (GRCm39)	missense	probably damaging	1.00
R0462:Dnah2	UTSW	11	69,350,027 (GRCm39)	missense	probably damaging	1.00
R0463:Dnah2	UTSW	11	69,313,952 (GRCm39)	missense	probably damaging	1.00
R0611:Dnah2	UTSW	11	69,390,020 (GRCm39)	missense	probably damaging	1.00
R0626:Dnah2	UTSW	11	69,368,509 (GRCm39)	missense	probably benign	0.07
R0924:Dnah2	UTSW	11	69,312,134 (GRCm39)	missense	probably damaging	1.00
R0968:Dnah2	UTSW	11	69,339,345 (GRCm39)	missense	possibly damaging	0.67
R1066:Dnah2	UTSW	11	69,338,645 (GRCm39)	missense	probably damaging	1.00
R1183:Dnah2	UTSW	11	69,337,474 (GRCm39)	missense	possibly damaging	0.95
R1184:Dnah2	UTSW	11	69,390,016 (GRCm39)	missense	probably damaging	1.00
R1186:Dnah2	UTSW	11	69,406,526 (GRCm39)	missense	probably damaging	0.99
R1453:Dnah2	UTSW	11	69,341,876 (GRCm39)	missense	probably damaging	0.99
R1498:Dnah2	UTSW	11	69,411,493 (GRCm39)	splice site	probably null
R1538:Dnah2	UTSW	11	69,368,028 (GRCm39)	missense	probably benign	0.17
R1574:Dnah2	UTSW	11	69,405,514 (GRCm39)	missense	probably benign	0.26
R1574:Dnah2	UTSW	11	69,405,514 (GRCm39)	missense	probably benign	0.26
R1590:Dnah2	UTSW	11	69,412,024 (GRCm39)	missense	probably benign	0.00
R1590:Dnah2	UTSW	11	69,313,580 (GRCm39)	critical splice donor site	probably null
R1655:Dnah2	UTSW	11	69,364,680 (GRCm39)	missense	probably damaging	1.00
R1695:Dnah2	UTSW	11	69,405,517 (GRCm39)	missense	possibly damaging	0.74
R1726:Dnah2	UTSW	11	69,388,715 (GRCm39)	missense	probably damaging	1.00
R1764:Dnah2	UTSW	11	69,314,369 (GRCm39)	missense	probably damaging	1.00
R1815:Dnah2	UTSW	11	69,366,400 (GRCm39)	missense	probably damaging	1.00
R1822:Dnah2	UTSW	11	69,405,630 (GRCm39)	missense	probably damaging	1.00
R1859:Dnah2	UTSW	11	69,328,712 (GRCm39)	missense	probably damaging	0.99
R1911:Dnah2	UTSW	11	69,406,578 (GRCm39)	missense	possibly damaging	0.64
R1913:Dnah2	UTSW	11	69,355,756 (GRCm39)	missense	probably damaging	1.00
R1981:Dnah2	UTSW	11	69,365,151 (GRCm39)	missense	probably damaging	1.00
R2010:Dnah2	UTSW	11	69,349,184 (GRCm39)	critical splice donor site	probably null
R2016:Dnah2	UTSW	11	69,327,896 (GRCm39)	missense	probably damaging	0.97
R2017:Dnah2	UTSW	11	69,327,896 (GRCm39)	missense	probably damaging	0.97
R2044:Dnah2	UTSW	11	69,415,066 (GRCm39)	missense	probably benign	0.14
R2077:Dnah2	UTSW	11	69,387,432 (GRCm39)	missense	possibly damaging	0.73
R2096:Dnah2	UTSW	11	69,346,742 (GRCm39)	missense	probably damaging	0.98
R2099:Dnah2	UTSW	11	69,384,063 (GRCm39)	missense	probably damaging	1.00
R2127:Dnah2	UTSW	11	69,349,011 (GRCm39)	missense	probably benign	0.02
R2128:Dnah2	UTSW	11	69,349,011 (GRCm39)	missense	probably benign	0.02
R2146:Dnah2	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
R2147:Dnah2	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
R2150:Dnah2	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
R2404:Dnah2	UTSW	11	69,328,047 (GRCm39)	missense	probably damaging	0.99
R2510:Dnah2	UTSW	11	69,415,032 (GRCm39)	nonsense	probably null
R2517:Dnah2	UTSW	11	69,407,470 (GRCm39)	missense	probably damaging	1.00
R3014:Dnah2	UTSW	11	69,321,304 (GRCm39)	missense	probably benign
R3741:Dnah2	UTSW	11	69,339,295 (GRCm39)	missense	probably damaging	1.00
R3814:Dnah2	UTSW	11	69,383,476 (GRCm39)	splice site	probably null
R3872:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3873:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3874:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3875:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3881:Dnah2	UTSW	11	69,342,173 (GRCm39)	missense	possibly damaging	0.94
R3953:Dnah2	UTSW	11	69,344,929 (GRCm39)	missense	probably damaging	1.00
R3956:Dnah2	UTSW	11	69,374,847 (GRCm39)	missense	probably benign	0.00
R4501:Dnah2	UTSW	11	69,368,485 (GRCm39)	missense	probably benign
R4515:Dnah2	UTSW	11	69,356,457 (GRCm39)	missense	possibly damaging	0.61
R4612:Dnah2	UTSW	11	69,374,193 (GRCm39)	missense	possibly damaging	0.93
R4625:Dnah2	UTSW	11	69,354,487 (GRCm39)	missense	probably damaging	1.00
R4627:Dnah2	UTSW	11	69,356,202 (GRCm39)	missense	probably damaging	1.00
R4642:Dnah2	UTSW	11	69,387,385 (GRCm39)	missense	probably benign	0.00
R4683:Dnah2	UTSW	11	69,349,768 (GRCm39)	missense	probably damaging	1.00
R4698:Dnah2	UTSW	11	69,389,358 (GRCm39)	missense	probably damaging	1.00
R4710:Dnah2	UTSW	11	69,368,903 (GRCm39)	missense	probably damaging	1.00
R4712:Dnah2	UTSW	11	69,407,416 (GRCm39)	missense	possibly damaging	0.47
R4713:Dnah2	UTSW	11	69,367,514 (GRCm39)	missense	probably damaging	1.00
R4717:Dnah2	UTSW	11	69,320,183 (GRCm39)	missense	probably benign	0.00
R4740:Dnah2	UTSW	11	69,348,868 (GRCm39)	missense	probably damaging	0.96
R4780:Dnah2	UTSW	11	69,364,697 (GRCm39)	missense	probably damaging	0.97
R4825:Dnah2	UTSW	11	69,314,031 (GRCm39)	missense	probably damaging	1.00
R4864:Dnah2	UTSW	11	69,313,416 (GRCm39)	missense	probably damaging	0.98
R4868:Dnah2	UTSW	11	69,354,474 (GRCm39)	missense	probably damaging	1.00
R4879:Dnah2	UTSW	11	69,367,517 (GRCm39)	missense	probably damaging	1.00
R4908:Dnah2	UTSW	11	69,411,973 (GRCm39)	missense	probably benign	0.00
R4911:Dnah2	UTSW	11	69,389,930 (GRCm39)	critical splice donor site	probably null
R4962:Dnah2	UTSW	11	69,346,799 (GRCm39)	nonsense	probably null
R5015:Dnah2	UTSW	11	69,388,708 (GRCm39)	missense	possibly damaging	0.89
R5049:Dnah2	UTSW	11	69,338,992 (GRCm39)	missense	probably damaging	1.00
R5055:Dnah2	UTSW	11	69,411,599 (GRCm39)	missense	possibly damaging	0.67
R5153:Dnah2	UTSW	11	69,411,759 (GRCm39)	missense	possibly damaging	0.84
R5155:Dnah2	UTSW	11	69,313,362 (GRCm39)	missense	probably damaging	1.00
R5186:Dnah2	UTSW	11	69,326,710 (GRCm39)	missense	probably damaging	1.00
R5187:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5208:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5252:Dnah2	UTSW	11	69,420,295 (GRCm39)	missense	probably damaging	0.98
R5296:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5298:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5299:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5301:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5324:Dnah2	UTSW	11	69,348,819 (GRCm39)	missense	probably benign	0.07
R5350:Dnah2	UTSW	11	69,406,862 (GRCm39)	missense	possibly damaging	0.48
R5377:Dnah2	UTSW	11	69,312,674 (GRCm39)	missense	probably damaging	1.00
R5393:Dnah2	UTSW	11	69,391,683 (GRCm39)	missense	probably benign
R5421:Dnah2	UTSW	11	69,326,462 (GRCm39)	missense	probably damaging	1.00
R5452:Dnah2	UTSW	11	69,415,209 (GRCm39)	missense	probably damaging	1.00
R5461:Dnah2	UTSW	11	69,364,177 (GRCm39)	critical splice donor site	probably null
R5474:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5476:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5477:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5510:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5527:Dnah2	UTSW	11	69,328,014 (GRCm39)	nonsense	probably null
R5566:Dnah2	UTSW	11	69,407,395 (GRCm39)	nonsense	probably null
R5587:Dnah2	UTSW	11	69,328,068 (GRCm39)	missense	probably damaging	1.00
R5628:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5688:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5690:Dnah2	UTSW	11	69,382,370 (GRCm39)	missense	probably benign	0.15
R5711:Dnah2	UTSW	11	69,326,216 (GRCm39)	missense	probably damaging	1.00
R5735:Dnah2	UTSW	11	69,321,643 (GRCm39)	missense	possibly damaging	0.93
R5826:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5913:Dnah2	UTSW	11	69,339,256 (GRCm39)	missense	probably damaging	1.00
R5914:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5960:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5961:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5961:Dnah2	UTSW	11	69,321,974 (GRCm39)	missense	probably damaging	1.00
R5977:Dnah2	UTSW	11	69,411,707 (GRCm39)	missense	possibly damaging	0.79
R6020:Dnah2	UTSW	11	69,391,665 (GRCm39)	missense	probably benign
R6036:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6036:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6050:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6086:Dnah2	UTSW	11	69,406,834 (GRCm39)	missense	probably benign	0.30
R6115:Dnah2	UTSW	11	69,337,475 (GRCm39)	missense	probably damaging	1.00
R6123:Dnah2	UTSW	11	69,409,185 (GRCm39)	missense	probably benign	0.29
R6159:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6159:Dnah2	UTSW	11	69,349,368 (GRCm39)	missense	probably damaging	1.00
R6163:Dnah2	UTSW	11	69,411,729 (GRCm39)	nonsense	probably null
R6171:Dnah2	UTSW	11	69,313,868 (GRCm39)	missense	probably damaging	1.00
R6263:Dnah2	UTSW	11	69,348,238 (GRCm39)	missense	probably damaging	1.00
R6298:Dnah2	UTSW	11	69,382,467 (GRCm39)	missense	probably benign	0.25
R6352:Dnah2	UTSW	11	69,339,053 (GRCm39)	missense	probably damaging	1.00
R6399:Dnah2	UTSW	11	69,349,344 (GRCm39)	missense	probably damaging	0.98
R6466:Dnah2	UTSW	11	69,430,241 (GRCm39)	missense	probably benign
R6478:Dnah2	UTSW	11	69,406,836 (GRCm39)	missense	probably benign	0.01
R6516:Dnah2	UTSW	11	69,356,212 (GRCm39)	missense	probably benign	0.34
R6538:Dnah2	UTSW	11	69,328,023 (GRCm39)	missense	possibly damaging	0.87
R6802:Dnah2	UTSW	11	69,314,516 (GRCm39)	missense	probably damaging	1.00
R6861:Dnah2	UTSW	11	69,346,789 (GRCm39)	missense	possibly damaging	0.64
R6869:Dnah2	UTSW	11	69,320,297 (GRCm39)	missense	probably damaging	1.00
R6894:Dnah2	UTSW	11	69,375,086 (GRCm39)	missense	probably benign	0.12
R6935:Dnah2	UTSW	11	69,312,567 (GRCm39)	missense	probably damaging	1.00
R7017:Dnah2	UTSW	11	69,382,373 (GRCm39)	nonsense	probably null
R7073:Dnah2	UTSW	11	69,321,318 (GRCm39)	nonsense	probably null
R7111:Dnah2	UTSW	11	69,337,579 (GRCm39)	splice site	probably null
R7125:Dnah2	UTSW	11	69,327,008 (GRCm39)	missense	probably damaging	0.99
R7137:Dnah2	UTSW	11	69,382,381 (GRCm39)	missense	probably damaging	1.00
R7190:Dnah2	UTSW	11	69,439,923 (GRCm39)	splice site	probably null
R7214:Dnah2	UTSW	11	69,321,935 (GRCm39)	missense	probably damaging	1.00
R7227:Dnah2	UTSW	11	69,312,222 (GRCm39)	missense	probably damaging	0.99
R7238:Dnah2	UTSW	11	69,349,972 (GRCm39)	critical splice donor site	probably null
R7256:Dnah2	UTSW	11	69,321,920 (GRCm39)	missense	probably damaging	1.00
R7267:Dnah2	UTSW	11	69,391,643 (GRCm39)	missense	probably damaging	1.00
R7420:Dnah2	UTSW	11	69,369,623 (GRCm39)	missense	possibly damaging	0.94
R7421:Dnah2	UTSW	11	69,383,631 (GRCm39)	missense	probably benign	0.25
R7437:Dnah2	UTSW	11	69,389,453 (GRCm39)	missense	probably damaging	1.00
R7461:Dnah2	UTSW	11	69,439,816 (GRCm39)	critical splice donor site	probably null
R7473:Dnah2	UTSW	11	69,382,484 (GRCm39)	missense	probably damaging	0.99
R7528:Dnah2	UTSW	11	69,391,622 (GRCm39)	missense	probably damaging	0.99
R7613:Dnah2	UTSW	11	69,439,816 (GRCm39)	critical splice donor site	probably null
R7615:Dnah2	UTSW	11	69,326,130 (GRCm39)	missense	probably damaging	0.99
R7626:Dnah2	UTSW	11	69,389,511 (GRCm39)	missense	probably damaging	0.99
R7745:Dnah2	UTSW	11	69,342,144 (GRCm39)	nonsense	probably null
R7764:Dnah2	UTSW	11	69,348,984 (GRCm39)	missense	probably benign	0.29
R7793:Dnah2	UTSW	11	69,386,040 (GRCm39)	missense	probably benign	0.00
R7819:Dnah2	UTSW	11	69,407,419 (GRCm39)	missense	probably benign	0.01
R7881:Dnah2	UTSW	11	69,322,064 (GRCm39)	missense	probably damaging	1.00
R7900:Dnah2	UTSW	11	69,409,254 (GRCm39)	missense	probably damaging	1.00
R7916:Dnah2	UTSW	11	69,311,974 (GRCm39)	critical splice acceptor site	probably null
R7921:Dnah2	UTSW	11	69,411,660 (GRCm39)	missense	probably benign
R7928:Dnah2	UTSW	11	69,321,661 (GRCm39)	missense	probably damaging	0.98
R7937:Dnah2	UTSW	11	69,408,511 (GRCm39)	nonsense	probably null
R7995:Dnah2	UTSW	11	69,411,563 (GRCm39)	missense	possibly damaging	0.77
R8202:Dnah2	UTSW	11	69,369,649 (GRCm39)	missense	probably benign	0.00
R8208:Dnah2	UTSW	11	69,411,678 (GRCm39)	missense	probably benign	0.05
R8215:Dnah2	UTSW	11	69,326,193 (GRCm39)	missense	probably damaging	1.00
R8279:Dnah2	UTSW	11	69,366,399 (GRCm39)	missense	probably damaging	1.00
R8338:Dnah2	UTSW	11	69,378,122 (GRCm39)	missense	probably damaging	1.00
R8348:Dnah2	UTSW	11	69,320,273 (GRCm39)	missense	possibly damaging	0.95
R8405:Dnah2	UTSW	11	69,349,289 (GRCm39)	missense	probably damaging	1.00
R8407:Dnah2	UTSW	11	69,350,104 (GRCm39)	missense	probably benign	0.00
R8493:Dnah2	UTSW	11	69,343,804 (GRCm39)	missense	probably damaging	1.00
R8673:Dnah2	UTSW	11	69,405,523 (GRCm39)	missense	probably benign	0.23
R8725:Dnah2	UTSW	11	69,415,005 (GRCm39)	missense	probably damaging	1.00
R8727:Dnah2	UTSW	11	69,415,005 (GRCm39)	missense	probably damaging	1.00
R8730:Dnah2	UTSW	11	69,384,087 (GRCm39)	missense	possibly damaging	0.73
R8804:Dnah2	UTSW	11	69,356,511 (GRCm39)	missense	probably benign	0.01
R8876:Dnah2	UTSW	11	69,382,348 (GRCm39)	missense	probably damaging	1.00
R8894:Dnah2	UTSW	11	69,383,048 (GRCm39)	missense	probably benign	0.01
R8938:Dnah2	UTSW	11	69,328,754 (GRCm39)	missense	probably damaging	0.99
R9044:Dnah2	UTSW	11	69,420,247 (GRCm39)	missense	probably benign
R9085:Dnah2	UTSW	11	69,320,224 (GRCm39)	missense	possibly damaging	0.69
R9110:Dnah2	UTSW	11	69,435,208 (GRCm39)	missense	probably benign
R9156:Dnah2	UTSW	11	69,313,687 (GRCm39)	missense
R9251:Dnah2	UTSW	11	69,406,619 (GRCm39)	missense	probably damaging	1.00
R9258:Dnah2	UTSW	11	69,368,079 (GRCm39)	missense	probably damaging	1.00
R9279:Dnah2	UTSW	11	69,409,104 (GRCm39)	missense	probably benign	0.01
R9318:Dnah2	UTSW	11	69,375,155 (GRCm39)	missense	probably benign	0.07
R9321:Dnah2	UTSW	11	69,338,939 (GRCm39)	critical splice donor site	probably null
R9350:Dnah2	UTSW	11	69,384,073 (GRCm39)	missense	probably benign	0.10
R9358:Dnah2	UTSW	11	69,406,592 (GRCm39)	missense	probably damaging	0.99
R9417:Dnah2	UTSW	11	69,326,990 (GRCm39)	missense	probably damaging	1.00
R9420:Dnah2	UTSW	11	69,368,942 (GRCm39)	missense	probably benign	0.09
R9438:Dnah2	UTSW	11	69,364,220 (GRCm39)	missense	probably damaging	1.00
R9469:Dnah2	UTSW	11	69,321,896 (GRCm39)	missense	probably damaging	1.00
R9487:Dnah2	UTSW	11	69,406,617 (GRCm39)	missense	possibly damaging	0.47
R9495:Dnah2	UTSW	11	69,345,208 (GRCm39)	missense	possibly damaging	0.89
R9579:Dnah2	UTSW	11	69,368,041 (GRCm39)	missense	probably damaging	1.00
R9608:Dnah2	UTSW	11	69,344,888 (GRCm39)	missense	probably null	1.00
R9651:Dnah2	UTSW	11	69,341,824 (GRCm39)	critical splice donor site	probably null
R9662:Dnah2	UTSW	11	69,343,763 (GRCm39)	missense	probably benign
RF004:Dnah2	UTSW	11	69,328,013 (GRCm39)	missense	probably benign	0.24
U24488:Dnah2	UTSW	11	69,374,648 (GRCm39)	missense	probably damaging	0.99
X0021:Dnah2	UTSW	11	69,339,388 (GRCm39)	missense	possibly damaging	0.81
Z1088:Dnah2	UTSW	11	69,321,619 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah2	UTSW	11	69,312,647 (GRCm39)	missense	possibly damaging	0.46
Z1176:Dnah2	UTSW	11	69,407,349 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah2	UTSW	11	69,407,307 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah2	UTSW	11	69,389,493 (GRCm39)	missense	probably benign	0.12
Z1176:Dnah2	UTSW	11	69,377,880 (GRCm39)	missense	possibly damaging	0.46
Z1176:Dnah2	UTSW	11	69,341,946 (GRCm39)	missense	probably benign
Z1177:Dnah2	UTSW	11	69,435,383 (GRCm39)	critical splice acceptor site	probably null
Z1177:Dnah2	UTSW	11	69,354,279 (GRCm39)	missense	possibly damaging	0.63

Predicted Primers

PCR Primer
(F):5'- GTGTCAGAAATACGCTGAAGTTAG -3'
(R):5'- GCCAGGGATTTCATTCCAAACTTTTG -3'

Sequencing Primer
(F):5'- TACGCTGAAGTTAGAATTGCATGG -3'
(R):5'- CCTTACAGCTGGATCTCATGAAGG -3'

Posted On

2016-04-27